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Ba

" in MedChemExpress (MCE) Product Catalog:

115

Inhibitors & Agonists

6

Peptides

3

Inhibitory Antibodies

10

Natural
Products

19

Recombinant Proteins

11

Isotope-Labeled Compounds

6

Antibodies

1

Click Chemistry

5

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-114314

    HBV Infection
    BA-53038B is a HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly. BA-53038B has antiviral activity for hepatitis B virus (HBV) with an EC50 value of 3.32 μM. BA-53038B can be used for the research of chronic hepatitis B .
    BA-53038B
  • HY-P1423A

    Bombesin Receptor Metabolic Disease Cancer
    BA 1 TFA is a potent agonist for the bombesin (BB) family of receptors. BA1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM .
    BA 1 TFA
  • HY-B0460
    Tiotropium bromide monohydrate
    1 Publications Verification

    Ba-679 BR monohydrate

    mAChR Neurological Disease
    Tiotropium bromide (BA-679 BR) monohydrate is a long-acting muscarinic receptor antagonist .
    Tiotropium bromide monohydrate
  • HY-W099602

    Ba 51-090453

    Others Metabolic Disease
    Dodecane (Ba 51-090453) is an ester product.
    Dodecane
  • HY-B1486
    Oxprenolol hydrochloride
    1 Publications Verification

    Ba 39089

    Adrenergic Receptor Cardiovascular Disease
    Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle .
    Oxprenolol hydrochloride
  • HY-120577

    Others Cardiovascular Disease
    BA 41899 is a purely calcium-sensitizing agent. BA 41899 is completely devoid of phosphodiesterase (PDE) III inhibitory activity or any other known inotropic mechanism. BA 41899 can be used for the research of cardiovascular diseases, such as congestive heart failure (CHF) .
    BA 41899
  • HY-145871

    HBV Infection
    BA38017 is a potent HBV core protein assembly modulator. BA38017 inhibits HBV replication with an EC50 of 0.20 μM .
    BA38017
  • HY-P1423

    Bombesin Receptor Metabolic Disease Cancer
    BA 1 is a potent agonist for the bombesin (BB) family of receptors. BA 1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM .
    BA 1
  • HY-A0171A

    Ba-30803

    5-HT Receptor Neurological Disease
    Benzoctamine hydrochloride (Ba-30803) is a psychoactive agent with anti-anxiety effect. Benzoctamine hydrochloride blocks the central postsynaptic serotonin receptors and decreases 5-HT turnover in the brain .
    Benzoctamine hydrochloride
  • HY-B1486A

    Ba 39089 free Base

    Adrenergic Receptor Cardiovascular Disease
    Oxprenolol (Ba 39089 free base) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle .
    Oxprenolol
  • HY-163735

    Potassium Channel Cardiovascular Disease
    BA6b9 is an allosteric inhibitor of SK4 channels that targets the CaM–PIP2-binding domain with a IC50 value of 8.6 µM (WT SK4). BA6b9 inhibits SK4 channels by interacting with two specific residues, Arg191 and His192 in the S4–S5 linker. BA6b9 significantly prolongs atrial and atrioventricular effective refractory period (ERP) and reduces atrial fibrillation (AF) induction in rat isolated hearts, which has the potential to be used for the research of arrhythmia .
    BA6b9
  • HY-162596

    Ba-1049

    ROCK Neurological Disease
    NRL-1049 (BA-1049) is a ROCK2 selective inhibitor (IC50: 0.59 µM and 26 µM for ROCK2 and ROCK1 respectively). NRL-1049 reduces Lysophosphatidic acid induced ROCK activation in endothelial cells. NRL-1049 reduces lesion volume and hemorrhagic transformation in a mouse model of cavernous angiomas. NRL-1049 also preserves the BBB and suppresses seizures after brain injury, and inhibits hemorrhagic transformation after ischemic stroke in mice .
    NRL-1049
  • HY-17360
    Tiotropium Bromide
    1 Publications Verification

    Ba679 BR

    mAChR Neurological Disease
    Tiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.
    Tiotropium Bromide
  • HY-108742
    Abaloparatide
    1 Publications Verification

    Ba 058; BIM 44058

    PTHR Arrestin Metabolic Disease Cancer
    Abaloparatide (BA 058) is a parathyroid hormone receptor 1 (PTHR1) analog. Abaloparatide also is a selective PTHR1 activator. Abaloparatide enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide enhances bone formation and cortical structure in mice. Abaloparatide has the potential for the research of osteoporosis .
    Abaloparatide
  • HY-P9988

    Ba301

    ADC Antibody TAM Receptor Cancer
    Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE (HY-15162) via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011) .
    Mecbotamab
  • HY-145622

    Ba3011; CAB-Axl-ADC; CAB-anti-Axl-ADC

    TAM Receptor Cancer
    Mecbotamab vedotin (BA301) is an IgG1 antibody inhibitor of anti-(human tyrosine kinase receptor AXL) (human-Mus musculus monoclonal BA301 γ1-chain). Mecbotamab vedotin can be used to make immunoconjugates for Methods of Axl-expressing cancers research .
    Mecbotamab vedotin
  • HY-106564A

    Ba 598Br; Flubron

    Others Inflammation/Immunology
    Flutropium bromide (Ba 598Br) is a organic bromide salt of flutropium. Flutropium bromide shows an anticholinergic effect. Flutropium bromide effectively suppresses spasms and it can be used for the research of asthma and chronic obstructive pulmonary disease .
    Flutropium bromide
  • HY-108742A
    Abaloparatide TFA
    1 Publications Verification

    Ba 058 TFA; BIM 44058 TFA

    Arrestin PTHR Metabolic Disease Endocrinology Cancer
    Abaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 (PTHR1) analogue. Abaloparatide TFA also is a selective PTHR1 activator. Abaloparatide TFA enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide TFA enhances bone formation and cortical structure in mice. Abaloparatide TFA has the potential for the research of osteoporosis .
    Abaloparatide TFA
  • HY-103370

    Ba 7602-06

    Chloride Channel Inflammation/Immunology
    Talniflumate (BA 7602-06) is the proagent of Niflumic acid (HY-B0493), exerting its activity in the body through conversion to niflumic acid by esterase . Talniflumate is an orally active Ca 2+-activated Cl - channel (CaCC) blocker. Talniflumate can be used as an analgesic and anti-inflammatory agent in cystic fibrosis mouse model of distal intestinal obstructive syndrome .
    Talniflumate
  • HY-17360R

    Ba679 BR (Standard)

    mAChR Neurological Disease
    Tiotropium (Bromide) (Standard) is the analytical standard of Tiotropium (Bromide). This product is intended for research and analytical applications. Tiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.
    Tiotropium Bromide (Standard)
  • HY-B1486S

    Ba 39089-d7

    Adrenergic Receptor Cardiovascular Disease
    Oxprenolol-d7 (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle[1].
    Oxprenolol-d7 hydrochloride
  • HY-17360S

    Ba679 BR-d3

    Isotope-Labeled Compounds mAChR Neurological Disease
    Tiotropium-d3 (bromide) is the deuterium labeled Tiotropium (Bromide). Tiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.
    Tiotropium-d3 bromide
  • HY-17360S1

    Ba679 BR-d6

    Isotope-Labeled Compounds mAChR Neurological Disease
    Tiotropium-d6 (bromide) is deuterium labeled Tiotropium (Bromide). Tiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.
    Tiotropium-d6 bromide
  • HY-145627

    Ba3021; Anti-ROR2 ADC; CAB-ROR2-ADC

    Antibody-Drug Conjugates (ADCs) Microtubule/Tubulin Cancer
    Ozuriftamab vedotin (BA3021), an antibody-drug conjugate (ADC), is a conditionally active biologic (CAB) anti-receptor tyrosine kinase orphan receptor 2 (ROR2) humanized monoclonal antibody Ozuriftamab (HY-145626) conjugated to VcMMAE (HY-15575). Ozuriftamab vedotin has antitumor activities .
    Ozuriftamab vedotin
  • HY-U00007

    Ba 2652; StilBamidin

    Fungal Infection Cancer
    Stilbamidine is a diamidine compound derived from Stilbene and used chiefly in the form of its crystalline isethionate salt in treating various fungal infections.
    Stilbamidine
  • HY-U00007A
    Stilbamidine dihydrochloride
    1 Publications Verification

    Ba 2652 dihydrochloride; StilBamidin dihydrochloride

    Fungal Infection Cancer
    Stilbamidine dihydrochloride is a diamidine compound derived from Stilbene and used chiefly in the form of its crystalline isethionate salt in treating various fungal infections.
    Stilbamidine dihydrochloride
  • HY-119614

    Ba-32644

    Parasite Bacterial Infection
    Niridazole is an anaerobic and microaerophilic bacterial inhibitor with IC50 values ranging from 0.0037 to 1.0 μg/mL .
    Niridazole
  • HY-145626

    Ba302

    ADC Antibody Cancer
    Ozuriftamab is a naked human IgG1 kappa antibody of receptor tyrosine kinase-like orphan receptor 2 ROR2, can be used to synthesis ADC .
    Ozuriftamab
  • HY-41700

    (R)-Alanine; Ba 2776; D-α-Alanine

    Endogenous Metabolite Neurological Disease
    D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR .
    D-Alanine
  • HY-A0171

    Ba-30803 free Base

    Others Neurological Disease
    Benzoctamine is an orally active and potent psychoactive agent which possesses tranquillizing properties. Benzoctamine increases the turnover rate of catecholamines. Benzoctamine enhances the [3H]noradrenaline uptake in the rat heart. Benzoctamine also accelerated the disappearance of intracisternally injected [3H]noradrenaline .
    Benzoctamine
  • HY-118384
    Sangivamycin
    2 Publications Verification

    NSC 65346; Ba-90912

    PKC Nucleoside Antimetabolite/Analog Cancer
    Sangivamycin (NSC 65346), a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an Ki of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers .
    Sangivamycin
  • HY-41700S1

    (R)-Alanine-d4; Ba 2776-d4; D-α-Alanine-d4

    Endogenous Metabolite Others
    D-Alanine-d4 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.
    D-Alanine-d4
  • HY-41700S

    (R)-Alanine-d3; Ba 2776-d3; D-α-Alanine-d3

    Isotope-Labeled Compounds Endogenous Metabolite Others
    D-Alanine-d3 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.
    D-Alanine-d3
  • HY-41700S2

    (R)-Alanine-d1; Ba 2776-d1; D-α-Alanine-d1

    Isotope-Labeled Compounds Endogenous Metabolite Neurological Disease
    D-Alanine-d is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR[1].
    D-Alanine-d1
  • HY-41700S3

    (R)-Alanine-d7; Ba 2776-d7; D-α-Alanine-d7

    Endogenous Metabolite Neurological Disease
    D-Alanine-d7 is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.
    D-Alanine-d7
  • HY-N0309R

    Aldose Reductase Metabolic Disease
    Soyasaponin Ba (Standard) is the analytical standard of Soyasaponin Ba. This product is intended for research and analytical applications. Soyasaponin Ba is a soyasaponin isolated from Phaseolus vulgaris, acts as an aldose reductase inhibitors (ARI) .
    Soyasaponin Ba (Standard)
  • HY-N10443

    Parasite Apoptosis Autophagy Reactive Oxygen Species Infection
    Mammea A/BA has potent activity against Trypanosoma cruzi (T. cruzi). Mammea A/BA induces mitochondrial dysfunction, reactive oxygen species (ROS) production and DNA fragmentation, and increases number of acidic vacuoles. Mammea A/BA can induce apoptosis, autophagy and necrosis. Mammea A/BA can be used for researching chagas disease .
    Mammea A/BA
  • HY-126432S

    Isotope-Labeled Compounds Others
    (Rac)-BA-1049-d5 is deuterated labeled (Rac)-BA-1049.
    (Rac)-BA-1049-d5
  • HY-N0309
    Soyasaponin Ba
    1 Publications Verification

    Aldose Reductase Metabolic Disease
    Soyasaponin Ba is a soyasaponin isolated from Phaseolus vulgaris, acts as an aldose reductase inhibitors (ARI) .
    Soyasaponin Ba
  • HY-121726

    mTOR Autophagy Cardiovascular Disease
    3HOI-BA-01 is amTORinhibitor.3HOI-BA-01reduces infarct size and inducedautophagyin a murine myocardial ischemia/reperfusion injury model .
    3HOI-BA-01
  • HY-R01674

    MicroRNA Cancer
    hsa-miR-548ba mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-548ba mimic
    hsa-miR-548ba mimic
  • HY-RI01674

    MicroRNA Cancer
    hsa-miR-548ba inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-548ba inhibitor
    hsa-miR-548ba inhibitor
  • HY-RS05607

    Small Interfering RNA (siRNA) Others

    GP1BA Human Pre-designed siRNA Set A contains three designed siRNAs for GP1BA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GP1BA Human Pre-designed siRNA Set A
    GP1BA Human Pre-designed siRNA Set A
  • HY-R01674A

    MicroRNA Cancer
    hsa-miR-548ba agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-548ba agomir
    hsa-miR-548ba agomir
  • HY-RI01674A

    MicroRNA Cancer
    hsa-miR-548ba antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-548ba antagomir
    hsa-miR-548ba antagomir
  • HY-110173

    G protein-coupled Bile Acid Receptor 1 Metabolic Disease
    TC-G 1005 is a potent, selective and orally active agonist of the BA receptor Takeda G protein-coupled receptor 5 (TGR5), with EC50s of 0.72 and 6.2 nM for hTGR5 and mTGR5, respectively. TC-G 1005 can reduce glucose levels in vivo .
    TC-G 1005
  • HY-149304

    SARS-CoV Infection
    SARS-CoV-2-IN-40 (Compound 19) is a SARS-CoV-2 inhibitor. SARS-CoV-2-IN-40 inhibits SARS-CoV-2 BA.1 and BA.5 variant infection of Calu3 lung cells, with IC50s of 100 nM and 160 nM respectively .
    SARS-CoV-2-IN-40
  • HY-163076

    Apoptosis Others
    Anticancer agent 174 (BA-3) is an anticancer agent. Anticancer agent 174 induces tumor cell apoptosis through the mitochondrial pathway. Anticancer agent 174 inhibits cancer cell proliferation in melanoma mouse xenograft model .
    Anticancer agent 174
  • HY-149315

    SARS-CoV Infection
    SARS-CoV-2-IN-48 (compound 19) is a SARS-CoV-2 inhibitor with an IC50 of 2.7 μM for Omicron BA.1. SARS-CoV-2-IN-48 shows antiviral activities .
    SARS-CoV-2-IN-48
  • HY-163366

    Trk Receptor Cancer
    TRK-IN-28 (compound 30f) is a TRK inhibitor with the IC50 values of 0.55 nM, 25.1 nM and 5.4 nM against TRK WT, TRK G595R and TRK G667C, respectively. TRK-IN-2 shows antiproliferative activity with IC50 values of 9.5, 3.7, 205.0 and 48.3 nM against Ba/F3-ETV6-TRKA WT, Ba/F3-ETV6-TRKB WT, Ba/F3-LMNA-TRK G595R and Ba/F3-LMNA-TRKA G667C, respectively .
    TRK-IN-28

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