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Impurity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (4) Adrenergic Receptor (1) Angiotensin Receptor (5) Antibiotic (5) Autophagy (2) Bacterial (6) Biochemical Assay Reagents (6) Btk (6) Calcium Channel (1) Carbonic Anhydrase (1) Cholinesterase (ChE) (1) COX (7) Cytochrome P450 (1) DNA/RNA Synthesis (2) Dopamine Receptor (3) Drug Metabolite (138) EGFR (2) Endogenous Metabolite (1) Estrogen Receptor/ERR (2) Factor Xa (1) Fungal (2) GABA Receptor (1) Glucocorticoid Receptor (1) HCV (12) HDAC (1) Histamine Receptor (6) HIV (4) HMG-CoA Reductase (HMGCR) (2) iGluR (2) Influenza Virus (1) Isotope-Labeled Compounds (59) Keap1-Nrf2 (1) mAChR (2) Microtubule/Tubulin (3) NF-κB (1) Opioid Receptor (1) P-glycoprotein (1) PAK (1) Parasite (3) Phosphodiesterase (PDE) (3) PPAR (2) Progesterone Receptor (1) Prostaglandin Receptor (1) Reactive Oxygen Species (1) Reverse Transcriptase (1) SARS-CoV (3) SGLT (1) Thrombin (1) Toll-like Receptor (TLR) (1) VD/VDR (12) Virus Protease (3)
By Research Areas:	Cancer (41) Cardiovascular Disease (27) Endocrinology (8) Infection (35) Inflammation/Immunology (32) Metabolic Disease (21) Neurological Disease (16)
Click Chemistry:	Azide (3)

295

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Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-76937

Impurity of Doxercalciferol	VD/VDR	Endocrinology
Impurity of Doxercalciferol is an impurity of doxercalciferol, which is a synthetic analog of ergocalciferol (vitamin D2), used as a agent for secondary hyperparathyroidism and metabolic bone disease, and it suppresses parathyroid synthesis and secretion.

HY-15264

MC 1046 1 Publications Verification Impurity A of Calcipotriol	VD/VDR	Cancer
MC 1046(Impurity A of Calcipotriol) is an impurity of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.

HY-15265

Impurity F of Calcipotriol	VD/VDR	Cancer
Impurity F of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.

HY-13294

Impurity C of Alfacalcidol	VD/VDR	Metabolic Disease
Impurity of Alfacalcidol. Alfacalcidol (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.

HY-13293

Impurity C of Calcitriol	VD/VDR	Cancer
Impurity C of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

HY-13292

Impurity B of Calcitriol 1β,25-Dihydroxyvitamin-D3; 1-Epicalcitriol	VD/VDR	Cancer
Impurity B of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).

HY-131269

*Febuxostat impurity* 7**	Drug Metabolite	Others
Febuxostat impurity 7 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM .

HY-15266

24R-Calcipotriol PRI 2202; Impurity D of Calcipotriol	VD/VDR	Cancer
24R-Calcipotriol(PRI 2202) is an impurity of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.

HY-131270R

*Febuxostat impurity* 8 (Standard)**	Drug Metabolite	Others
Febuxostat impurity 8 (Standard) is the analytical standard of Febuxostat impurity 8. This product is intended for research and analytical applications. Febuxostat impurity 8 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM .

HY-131251

Cetirizine 3-chloro impurity	Drug Metabolite	Others
Cetirizine 3-chloro impurity is an impurity of Cetirizine 3-chloro .

HY-131270

*Febuxostat impurity* 8**	Drug Metabolite	Others
Febuxostat impurity 8 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM .

HY-131271

*Febuxostat impurity* 6**	Drug Metabolite	Others
Febuxostat impurity 6 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM .

HY-164226

*Rosuvastatin impurity-1*	Others	Others
Rosuvastatin impurity-1 is a reference substance of rosuvastatin impurities.

HY-164229

*Mianserin impurity-1*	Others	Others
Rosuvastatin impurity-1 is a reference substance of rosuvastatin impurities.

HY-164228

*Vericiguat impurity-3*	Others	Others
Vericiguat impurity-3 is an impurity of Vericiguat (HY-16774). Vericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator .

HY-131272R

*Febuxostat dicarboxylic acid impurity* (Standard)**	Drug Metabolite	Others
Febuxostat dicarboxylic acid impurity (Standard) is the analytical standard of Febuxostat dicarboxylic acid impurity. This product is intended for research and analytical applications. Febuxostat dicarboxylic acid impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM .

HY-131273R

*Febuxostat amide impurity* (Standard)**	Drug Metabolite	Others
Febuxostat amide impurity (Standard) is the analytical standard of Febuxostat amide impurity. This product is intended for research and analytical applications. Febuxostat amide impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM

HY-131272

Febuxostat dicarboxylic acid impurity	Drug Metabolite	Others
Febuxostat dicarboxylic acid impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM .

HY-131273

Febuxostat amide impurity	Drug Metabolite	Others
Febuxostat amide impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K_i of 0.6 nM

HY-133777

*Ciprofibrate impurity* A**	PPAR	Cancer
Ciprofibrate impurity A is an impurity of Ciprofibrate. Ciprofibrate (Win35833) is a potent peroxisome proliferator, increases the phosphorylation level of the PPARalpha .

HY-100663

*Gefitinib impurity* 2**	EGFR	Others Cancer
Gefitinib impurity 2 is the impurity of Gefitinib. Gefitinib (ZD1839; HY-50895) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC₅₀ of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC₅₀ of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity .

HY-134686

*Edoxaban impurity* 4**	Factor Xa Thrombin	Cardiovascular Disease
Edoxaban impurity 4 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with K_is of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention .

HY-133774

*Trityl olmesartan medoxomil impurity* III**	Drug Metabolite	Others
Trityl olmesartan medoxomil impurity III is an impurity of Trityl olmesartan medoxomil. Trityl olmesartan medoxomil is an intermediate of Olmesartan medoxomil .

HY-141410

Fluticasone dimer impurity	Drug Metabolite	Others
Fluticasone dimer impurity is a dimeric impurity of Fluticasone Propionate . Fluticasone propionate is a corticosteroid with comparatively high receptor affinity and topical activity .

HY-131255

Ziprasidone amino acid Ziprasidone Impurity C; Ziprasidone open ring Impurity	5-HT Receptor Dopamine Receptor	Neurological Disease
Ziprasidone amino acid (Ziprasidone Impurity C) is an impurity of Ziprasidone. Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist. Ziprasidone exhibits potent effects of antipsychotic activity .

HY-131265

*Mesalamine impurity* P**	PPAR PAK NF-κB	Inflammation/Immunology Cancer
Mesalamine impurity P is an impurity of Mesalamine (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB .

HY-131276R

*Olmesartan lactone impurity* (Standard)**	Angiotensin Receptor	Cardiovascular Disease
Olmesartan lactone impurity (Standard) is the analytical standard of Olmesartan lactone impurity. This product is intended for research and analytical applications. Olmesartan lactone impurity is a cyclic ester impurity of Olmesartan. Olmesartan is an angiotensin II receptor (AT1R) antagonist and has the potential for high blood pressure study .

HY-131276

Olmesartan lactone impurity	Angiotensin Receptor	Cardiovascular Disease
Olmesartan lactone impurity is a cyclic ester impurity of Olmesartan. Olmesartan is an angiotensin II receptor (AT1R) antagonist and has the potential for high blood pressure study .

HY-400785

*Dapagliflozin impurity* A**	Others	Cancer
Dapagliflozin impurity A (Compound A) is a dapagliflozin peroxide, a genotoxic impurity, can cause damage to human genetic material at very low concentrations, leading to genetic mutations and possibly tumorigenesis .

HY-131256

*Cetirizine Impurity* C**	Histamine Receptor	Inflammation/Immunology Endocrinology
Cetirizine Impurity C is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist ^{[1] ^{^{[2] ^.}}}

HY-131256A

*Cetirizine Impurity* C dihydrochloride**	Histamine Receptor	Inflammation/Immunology Endocrinology
Cetirizine Impurity C dihydrochloride is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist ^{[1] ^{^{[2] ^.}}}

HY-133780

*Afatinib impurity* 11**	EGFR Autophagy	Cancer
Afatinib impurity 11 is an impurity of Afatinib. Afatinib is an irreversible EGFR family inhibitor with IC₅₀s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR ^wt, EGFR ^L858R, EGFR ^L858R/T790M and HER2, respectively .

HY-121899

1-Oxo Ibuprofen Ibuprofen EP Impurity J	Drug Metabolite	Others
1-Oxo Ibuprofen (Ibuprofen EP impurity J) is a degradation product and a potential impurity in preparations of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC₅₀s of 13 μM and 370 μM, respectively .

HY-107495

*Betahistine EP Impurity* C** NSC19005	Histamine Receptor	Inflammation/Immunology
Betahistine EP Impurity C (NSC19005) is an impurity of Betahistine . Betahistine is a potent, orally active and well-tolerated histamine H1 receptor agonist and H3 receptor antagonist used for the study of rheumatoid arthritis (RA) .

HY-100069

*Fluazinam impurity* 1**	Fungal	Infection
Fluazinam impurity 1 is an impurity of Fluazinam with antifungal activity. Fluazinam impurity 1 is active against *Sphaerotheca fuliginea, Pyricularia oryzae* and *Rhizoctonia solani* .

HY-100069R

*Fluazinam impurity* 1 (Standard)**	Fungal	Infection
Fluazinam impurity 1 (Standard) is the analytical standard of Fluazinam impurity 1. This product is intended for research and analytical applications. Fluazinam impurity 1 is an impurity of Fluazinam with antifungal activity. Fluazinam impurity 1 is active against Sphaerotheca fuliginea, Pyricularia oryzae and Rhizoctonia solani .

HY-W568314

*Vericiguat impurity-1*	Others	Others
Vericiguat impurity-1 is the impurity of Vericiguat (HY-16774). Vericiguat impurity-1 can be used as impurity standards in impurity analysis, to develop selective and quantitative methods to determine impurities .

HY-164227

*Vericiguat impurity-2*	Biochemical Assay Reagents	Others
Vericiguat impurity-2 is the impurity of Vericiguat (HY-16774). Vericiguat impurity-2 can be used as impurity standards in impurity analysis, in order to develop selective and quantitative methods to determine impurities .

HY-W103960

*Mirabegron impurity-1*	Others	Metabolic Disease
Mirabegron impurity-1 is a potent and selective β₃- adrenergic receptor agonist. Mirabegron impurity-1 has the activity of inhibiting metabolism. Mirabegron impurity-1 can be used in the study of the treatment of bladder impurity .

HY-W103960R

*Mirabegron impurity-1 (Standard)*	Others	Metabolic Disease
Mirabegron impurity-1 (Standard) is the analytical standard of Mirabegron impurity-1. This product is intended for research and analytical applications. Mirabegron impurity-1 is a potent and selective β3- adrenergic receptor agonist. Mirabegron impurity-1 has the activity of inhibiting metabolism. Mirabegron impurity-1 can be used in the study of the treatment of bladder impurity .

HY-131281

*Ivabradine impurity* 1**	Drug Metabolite	Others
Ivabradine impurity 1 is an Ivabradine impurity. Ivabradine is an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel blocker .

HY-131282

*Ivabradine impurity* 2**	Drug Metabolite	Others
Ivabradine impurity 2 is an Ivabradine impurity. Ivabradine is an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel blocker .

HY-136589

*Verapamil EP Impurity* C hydrochloride** NSC-609249 hydrochloride	Calcium Channel P-glycoprotein Cytochrome P450	Metabolic Disease
NSC-609249 hydrochloride is an *impurity* of Verapamil (HY-14275). Verapamil is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor .

HY-W059210

*Ruxolitinib impurity-1*	Biochemical Assay Reagents	Others
Ruxolitinib impurity-1 is the impurity of Ruxolitinib (HY-50856), which can be used safety analysis of Ruxolitinib therapy .

HY-131258

*Ibuprofen impurity* 1**	COX	Inflammation/Immunology
Ibuprofen impurity 1 is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC₅₀s of 13 μM and 370 μM, respectively .

HY-133779R

*Gefitinib impurity* 5 (Standard)**	Drug Metabolite	Others Cancer
Gefitinib impurity 5 (Standard) is the analytical standard of Gefitinib impurity 5. This product is intended for research and analytical applications. Gefitinib impurity 5 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity .

HY-75035

*Calcipotriol Impurity* C**	VD/VDR	Inflammation/Immunology
Calcipotriol Impurity C is the impurity of Calcipotriol, Calcipotriol is a ligand of VDR-like receptors.

HY-136124

*Cetilistat impurity* 1**	Drug Metabolite	Others
Cetilistat impurity 1 is an impurity of Cetilistat. Cetilistat, an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC₅₀s of 54.8 nM, and 5.95 nM, respectively .

HY-133248

*Daclatasvir Impurity* C**	Drug Metabolite	Others
Daclatasvir Impurity C is the impurity of Daclatasvir. Daclatasvir is a potent HCV NS5A protein inhibitor .

HY-133247

*Daclatasvir Impurity* B**	Drug Metabolite	Others
Daclatasvir Impurity B is the impurity of Daclatasvir. Daclatasvir is a potent HCV NS5A protein inhibitor .

Cat. No.	Product Name	Type

HY-I0959

5-Chlorouracil Fluorouracil Impurity	Biochemical Assay Reagents
5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W035903

Ethanolamine hydrochloride

2-Aminoethanol hydrochloride

Buffer Reagents

Ethanolamine hydrochloride, is an organic compound used in various industrial applications. It is a white or colorless solid that is soluble in water and has a faint odor. One of the major uses of Ethanolamine hydrochloride is in the production of detergents and surfactants. Used as a raw material in the manufacture of compounds such as ethylenediaminetetraacetic acid (EDTA) and diethanolamine, which are commonly used in household and industrial cleaning products. Ethanolamine hydrochloride is also used in the synthesis of pharmaceuticals, agrochemicals and rubber processing agents. It acts as a buffer in certain chemical reactions, helping to adjust pH and maintain stability. Ethanolamine hydrochloride can be used for gas purification and metal corrosion inhibitor. Its ability to react with acid gases such as carbon dioxide and sulfur dioxide makes it useful for removing impurities from natural gas and other industrial gases. Overall, Ethanolamine hydrochloride is a multifunctional compound with many potential industrial applications. Its ability to act as a buffer, chelating agent, and corrosion inhibitor makes it an important tool in a variety of industries.

HY-I0959R

5-Chlorouracil (Standard)	Biochemical Assay Reagents
5-Chlorouracil (Standard) is the analytical standard of 5-Chlorouracil. This product is intended for research and analytical applications. 5-Chlorouracil (Fluorouracil Impurity) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name

HY-K1041

Seamless DNA Assembly Plus Kit 1 Publications Verification
MCE Seamless DNA Assembly Plus Kit contains an optimized mix of recombinase, reaction buffer, and additional cofactors that significantly improve the cloning efficiency and tolerance to impurities. This product can complete multiple DNA fragments recombination and takes only 5 minutes for single fragment, and the positive rate is more than 95%.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-100663

*Gefitinib impurity* 2**	Classification of Application Fields Disease Research Fields Cancer	EGFR
Gefitinib impurity 2 is the impurity of Gefitinib. Gefitinib (ZD1839; HY-50895) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC₅₀ of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC₅₀ of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity .

HY-131257

*Gefitinib impurity* 1**	Classification of Application Fields Disease Research Fields Cancer	Drug Metabolite
Gefitinib impurity 1 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC₅₀ of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC₅₀ of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity .

HY-133779

*Gefitinib impurity* 5**	Classification of Application Fields Disease Research Fields Cancer	Drug Metabolite
Gefitinib impurity 5 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC₅₀ of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC₅₀ of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity .

HY-W016644

(S)-1-Benzylpyrrolidin-3-ol	Cardiovascular Disease Classification of Application Fields Disease Research Fields	Others
(S)-1-Benzylpyrrolidin-3-ol (Compound 14) can be used to synthesis impurities of the anti-hypertensive agent Barnidipine hydrochloride (HY-107322) .

HY-112023

Lumisterol 3 (>90%) 9β,10α-Cholesta-5,7-dien-3β-ol; Cholecalciferol EP Impurity C	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Lumisterol 3 (>90%) (9β,10α-Cholesta-5,7-dien-3β-ol) is a normal human secosterooid metabolite from the class of vitamin D3 photoisomer derivatives. Lumisterol 3 (>90%) is used in the preparation of vitamin D .

HY-W778546

7-epi-10-Deacetyl baccatin III	Structural Classification Terpenoids Source classification Taxaceae Diterpenoids Plants Taxus baccata L.	Others
7-epi-10-Deacetyl baccatin III can be isolated from the degradation impurities in Docetaxel (HY-B0011) .

HY-W778547

7-epi-10-Oxo-10-deacetyl baccatin III 10-Dehydrobaccatin V	Structural Classification Terpenoids Source classification Taxaceae Diterpenoids Plants Taxus baccata L.	Others
7-epi-10-Oxo-10-deacetyl baccatin III (10-Dehydrobaccatin V) can be isolated from the degradation impurities in Docetaxel (HY-B0011) .

HY-131279

Olmesartan ethyl ester	Cardiovascular Disease Classification of Application Fields Disease Research Fields	Drug Metabolite
Olmesartan ethyl ester (compound 11) is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to in the high blood pressure study .

HY-116161

Bimatoprost isopropyl ester	Cardiovascular Disease Classification of Application Fields Disease Research Fields	Others
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC₅₀ values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.

Cat. No.	Product Name	Chemical Structure

HY-142217S

*Quetiapine dimer impurity-d8*
Quetiapine dimer impurity-d₈ is the deuterium labeled Quetiapine dimer impurity[1].

HY-W021399S

*Lidocaine impurity* 5-d6**
Lidocaine impurity 5-d₆ is deuterium labeled Lidocaine impurity 5.

HY-143951S

*Disulfiram impurity* 1-d10**
Disulfiram impurity 1-d₁₀ is the deuterium labeled Disulfiram impurity 1[1].

HY-143954S

*Epinephrine impurity* 19-d3 hydrochloride**
Epinephrine impurity 19-d₃ (hydrochloride) is the deuterium labeled Epinephrine impurity 19[1].

HY-143956S

*Fluorofenidone impurity* 1-d3**
Fluorofenidone impurity 1-d₃ is the deuterium labeled Fluorofenidone impurity 1[1].

HY-143961S

*Givinostat impurity* 5-d4**
Givinostat impurity 5-d₄ is the deuterium labeled Givinostat impurity 5[1].

HY-143968S

*Ketotifen impurity* 3-d4**
Ketotifen impurity 3-d₄ is the deuterium labeled Ketotifen impurity 3[1].

HY-143970S

*Ivabradine impurity* 7-d6**
Ivabradine impurity 7-d₆ is the deuterium labeled Ivabradine impurity 7[1].

HY-143974S

*Imiquimod impurity* 1-d6**
Imiquimod impurity 1-d₆ is the deuterium labeled Imiquimod impurity 1[1].

HY-143975S

*Loxapine impurity* 2-d8**
Loxapine impurity 2-d₈ is the deuterium labeled Loxapine impurity 2[1].

HY-143984S

*Minodronic acid impurity* 2-d4**
Minodronic acid impurity 2-d₄ is the deuterium labeled Minodronic acid impurity 2[1].

HY-143988S

*Nefazodone impurity* 3-d6**
Nefazodone impurity 3-d₆ is the deuterium labeled Nefazodone impurity 3[1].

HY-144146S

*Pramipexole impurity* 7-d10**
Pramipexole impurity 7-d₁₀ is the deuterium labeled Pramipexole impurity 7[1].

HY-144913S

*Bempedoic acid impurity* 1-d4**
Bempedoic acid impurity 1-d₄ is the deuterium labeled Bempedoic acid impurity 1[1].

HY-143938S

*Cyclobenzaprine impurity* 2-d3 hydrochloride**
Cyclobenzaprine impurity 2-d₃ (hydrochloride) is the deuterium labeled Cyclobenzaprine impurity 2 hydrochloride[1].

HY-143960S

*Givinostat impurity* 1-d10 hydrochloride**
Givinostat impurity 1-d₁₀ (hydrochloride) is the deuterium labeled Givinostat impurity 1 hydrochloride[1].

HY-144141S

*Nortriptyline impurity* 3-d3 hydrochloride**
Nortriptyline impurity 3-d₃ (hydrochloride) is the deuterium labeled Nortriptyline impurity 3 hydrochloride[1].

HY-144142S

*Orphenadrine impurity* 6-d3 hydrochloride**
Orphenadrine impurity 6-d₃ (hydrochloride) is the deuterium labeled Orphenadrine impurity 6 hydrochloride[1].

HY-143965S

*Imidacloprid impurity* 2-d4 hydrochloride**
Imidacloprid impurity 2-d₄ (hydrochloride) is the deuterium labeled Imidacloprid impurity 2-d₄ (hydrochloride)[1].

HY-142592S

*Clozapine EP impurity* D-d8**
Clozapine EP impurity D-d₈ is the deuterium labeled Clozapine EP impurity D[1].

HY-143907S

*Atorvastatin EP impurity* H-d5**
Atorvastatin EP impurity H-d₅ is the deuterium labeled Atorvastatin EP impurity H[1].

HY-143986S

*DM50 impurity* 1-d9**
DM50 impurity 1-d₉ is the deuterium labeled DM50 impurity 1[1].

HY-143987S

*DM51 impurity* 1-d9**
DM51 impurity 1-d₉ is the deuterium labeled DM51 impurity 1[1].

HY-143990S

*Modafinil EP impurity* B-d5**
Modafinil EP impurity B-d₅ is the deuterium labeled Modafinil EP impurity B[1].

HY-144242S

*Voriconazole EP impurity* D-d3**
Voriconazole EP impurity D-d₃ is the deuterium labeled Voriconazole EP impurity D[1].

HY-143941S

*Hydroxychloroquine EP impurity* D-d5 dihydrochloride**
Hydroxychloroquine EP impurity D-d₅ (dihydrochloride) is the deuterium labeled Hydroxychloroquine EP impurity D dihydrochloride[1].

HY-143977S

*Loxapine impurity* 3-d8 iodide**
Loxapine impurity 3-d₈ (iodide) is the deuterium labeled Loxapine impurity 3 iodide[1].

HY-143982S

*Mianserin EP impurity* E-d4 hydrochloride**
Mianserin EP impurity E-d₄ (hydrochloride) is the deuterium labeled Mianserin EP impurity E hydrochloride[1].

HY-144203S

*Trospium EP impurity* C-d8 chloride**
Trospium EP impurity C-d₈ (chloride) is the deuterium labeled Trospium EP impurity C chloride[1].

HY-143986S1

*DM50 impurity* 1-d9-1**
DM50 impurity 1-d₉-1 is the deuterium labeled DM50 impurity 1[1].

HY-143925S

*Betahistine impurity* 5-13C,d3**
Betahistine impurity 5- ¹³C,d₃ is the ¹³C- and deuterium labeled Betahistine impurity 5[1].

HY-143985S

*Maytansinoid DM4 impurity* 5-d6**
Maytansinoid DM4 impurity 5-d₆ is the deuterium labeled Maytansinoid DM4 impurity 5[1].

HY-143992S

*Maytansinoid DM4 impurity* 2-d6**
Maytansinoid DM4 impurity 2-d₆ is the deuterium labeled Maytansinoid DM4 impurity 2[1].

HY-143993S

*Maytansinoid DM4 impurity* 3-d6**
Maytansinoid DM4 impurity 3-d₆ is the deuterium labeled Maytansinoid DM4 impurity 3[1].

HY-143997S

*(Rac)-Nicotine EP impurity* A-d4 hydrochloride**
(Rac)-Nicotine EP impurity A-d₄ (hydrochloride) is the deuterium labeled (Rac)-Nicotine EP impurity A hydrochloride[1].

HY-144221S

*Tiotropium bromide EP impurity* A-d6**
Tiotropium bromide EP impurity A-d₆ is the deuterium labeled Tiotropium bromide EP impurity A[1].

HY-143963S

Irbesartan impurity 20-d4

Irbesartan impurity 20-d₄ is the deuterium labeled Irbesartan impurity 20[1]. Irbesartan impurity 20-d4 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-143964S

Irbesartan impurity 14-d4

Irbesartan impurity 14-d₄ is the deuterium labeled Irbesartan impurity 14[1]. Irbesartan impurity 14-d4 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-143980S

Losartan impurity 21-d4

Losartan impurity 21-d₄ is the deuterium labeled Losartan impurity 21[1]. Losartan impurity 21-d4 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-144150S

*Pelubiprofen impurity* 2-13C2,d6**
Pelubiprofen impurity 2- ¹³C₂,d₆ is the ¹³C- and deuterium labeled Pelubiprofen impurity 2[1].

HY-W178868S

*Lodoxamide impurity* 1-d5**
Lodoxamide impurity 1-d₅ is deuterium labeled n-Ethyl-2-hydroxyacetamide.

HY-W270557S

*Lodoxamide impurity* 2-d10**
Lodoxamide impurity 2-d₁₀ is deuterium labeled 2-(Diethylamino)-2-oxoacetic acid.

HY-13204S2

*rel-Biperiden EP impurity* A-d5**
rel-Biperiden EP impurity A-d₅ is deuterium labeled Biperiden (hydrochloride).

HY-13204S3

*rel-Biperiden EP impurity* B-d5**
rel-Biperiden EP impurity B-d₅ is deuterium labeled Biperiden (hydrochloride).

HY-W728503S

N-Nitroso Vonoprazan-13C,d3
N-Nitroso Vonoprazan-13C,d3 is the 13C- and deuterium labeled N-Nitroso Vonoprazan. N-Nitroso Vonoprazan is an impurity of Vonoprazan .

HY-20390S

*Lapatinib impurity* 18-d4**
Lapatinib impurity 18-d₄ is deuterium labeled 3-Chloro-4-((3-fluorobenzyl)oxy)aniline.

HY-Z2106S

*Vonoprazan impurity* 11-d5 fumarate**
Vonoprazan impurity 11-d₅ (fumarate) is deuterium labeled 1-(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-((5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylmethanamine (Vonoprazan Impurity).

HY-W336012S

*Metoprolol EP impurity* O-d7 hydrochloride**
Metoprolol EP impurity O-d₇ (hydrochloride) is the deuterium labeled 3,3'-(Isopropylazanediyl)bis(1-(4-(2-methoxyethyl)phenoxy)propan-2-ol)[1].

HY-14881S2

*Bedaquiline impurity* 2-d6**
Bedaquiline impurity 2-d₆ is deuterium labeled Bedaquiline. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit[1]. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis[2].

HY-104077S2

*Remdesivir impurity* 9-d4**
Remdesivir impurity 9-d₄ is deuterium labeled Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].

Cat. No.	Product Name		Classification