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Results for "

K1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) AAK1 (1) Adrenergic Receptor (2) Akt (6) Antibiotic (1) Apelin Receptor (APJ) (1) Apoptosis (2) Aurora Kinase (1) Autophagy (5) Bacterial (5) Bcr-Abl (1) Biochemical Assay Reagents (1) CaMK (3) Casein Kinase (2) CDK (5) Cyclin G-associated Kinase (GAK) (1) Drug Metabolite (2) EGFR (1) Endogenous Metabolite (14) Estrogen Receptor/ERR (1) Ferroptosis (2) FGFR (1) FLT3 (1) Fluorescent Dye (1) Fungal (1) GABA Receptor (2) GCGR (2) GLP Receptor (3) Histone Acetyltransferase (1) HIV (2) HSV (1) iGluR (1) IKK (1) Interleukin Related (1) IPK Superfamily (4) Isotope-Labeled Compounds (7) Keap1-Nrf2 (1) LIM Kinase (LIMK) (3) MAP3K (1) MAP4K (8) MAPKAPK2 (MK2) (1) MEK (4) Mesothelin (1) Mitophagy (2) Mixed Lineage Kinase (1) mTOR (4) Neuropeptide Y Receptor (1) Parasite (21) PDK-1 (3) PI3K (5) PI4K (1) PI4P5K (4) PIKfyve (1) PKA (1) PKC (2) Potassium Channel (2) Prostaglandin Receptor (2) PROTACs (2) Reactive Oxygen Species (2) Ribosomal S6 Kinase (RSK) (11) Salt-inducible Kinase (SIK) (2) SARS-CoV (2) SGK (2) Sirtuin (1) Small Interfering RNA (siRNA) (11) Sodium Channel (1) Somatostatin Receptor (1) Src (1) TGF-beta/Smad (1) TSH Receptor (1) Tyrosinase (1) ULK (2) VD/VDR (2) Virus Protease (2) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (51) Cardiovascular Disease (15) Infection (31) Inflammation/Immunology (13) Metabolic Disease (13) Neurological Disease (9)
Click Chemistry:	Azide (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (2) Mouse Pre-designed siRNA Sets (2) Human Pre-designed siRNA Sets (7) siRNAs (11)

137

Inhibitors & Agonists

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P5964A

K1 peptide TFA	GABA Receptor	Neurological Disease
K1 peptide TFA is a high-affinity peptide ligand for GABAA receptor-associated protein (GABARAP) ^[1].

HY-P990534

Anti-TSHR Antibody (K1-70) K1-70	TSH Receptor	Inflammation/Immunology
Anti-TSHR Antibody (K1-70) is a CHO-expressed human antibody that targets TSHR. Anti-TSHR Antibody (K1-70) has a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 143.54 kDa. For the isotype control of Anti-TSHR Antibody (K1-70), you can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-113164

Vitamin K1 2,3-epoxide	Endogenous Metabolite	Others
Vitamin K1 2,3-epoxide is an inactive metabolite form of Vitamin K1 (HY-N0684), which is reduced to active vitamin by microsomal epoxide reductase in the vitamin K epoxide cycle. Vitamin K1 2,3-epoxide is involved in blood clotting ^[1].

HY-N0684

Vitamin K1 4 Publications Verification Phylloquinone; Phytomenadione	Endogenous Metabolite	Cardiovascular Disease Cancer
Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-P5964

K1 peptide	GABA Receptor	Neurological Disease
K1 peptide is a high-affinity peptide ligand for GABAA receptor-associated protein (GABARAP) ^[1].

HY-P5204

Enterocin Hybrid 1 K1-EJ hybrid	Bacterial	Infection
Enterocin Hybrid 1 is a antibacterial agent, a antibacterial composition. Enterocin Hybrid 1 inhibits Vancomycin (HY-B0671)-resistant E. faecium, Staphylococcus haemoliticus ^[1].

HY-N7485

Gomisin K1 (-)-Gomisin K1	Others	Cancer
Gomisin K1 ((-)-Gomisin K1) is a lignan that exhibits anti-cancer activity. Gomisin K1 inhibits HeLa cell growth, with an IC₅₀ of 5.46 μM ^[1].

HY-N0684A

cis-Vitamin K1 cis-Phylloquinone; cis-Phytomenadione	Endogenous Metabolite	Cardiovascular Disease
Cis-Vitamin K1 is an endogenous metabolite of Vitamin K .

HY-N0684R

Vitamin K1 (Standard)	Endogenous Metabolite	Cardiovascular Disease
Vitamin K1 (Standard) is the analytical standard of Vitamin K1. This product is intended for research and analytical applications. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-P5203

Enterocin K1 EntK1	Bacterial	Infection
Enterocin K1 (EntK1) is a bacteriocin. Enterocin K1 is a ribosomal synthetic peptide. Enterocin K1 specifically targets *Enterococcus faecalis* via the Eep protein on the bacterial membrane. Enterocin K1 displays a potent antibacterial activity against VRE. Enterocin K1 can be used for related studies of VRE infections ^[1].

HY-113164S

Vitamin K1 2,3-epoxide-d7	Isotope-Labeled Compounds	Others
Vitamin K1 2,3-epoxide-d₇ is the deuterium labeled Vitamin K1 2,3-epoxide[1].

HY-127162

Prostaglandin K1 PGK1	Prostaglandin Receptor	Others
Prostaglandin K1 (compound 46) is a structurally modified analog of prostacyclin (prostanoid) with an EC₅₀ of 2800 nM for *EP1* and a K_i of 2800 nM ^[1].

HY-N0684S

Vitamin K1-d7	Endogenous Metabolite	Cardiovascular Disease
Vitamin K1-d₇ is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1][2].

HY-N0684AS

cis-Vitamin K1-d7	Endogenous Metabolite Isotope-Labeled Compounds	Others
cis-Vitamin K1-d₇ is the deuterium labeled cis-Vitamin K1, is an endogenous metabolite of Vitamin K .

HY-N0684S1

Vitamin K1-d4 Phylloquinone-d₄; Phytomenadione-d₄	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
Vitamin K1-d₄ is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1].

HY-N0684S3

Vitamin K1-13C6 Phylloquinone-¹³C₆; Phytomenadione-¹³C₆	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
Vitamin K1- ¹³C₆ is the ¹³C-labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-N0684S4

Vitamin K1-d3 Phylloquinone-d₃; Phytomenadione-d₃	Endogenous Metabolite Isotope-Labeled Compounds	Cardiovascular Disease
Vitamin K1-d₃ (Phylloquinone-d₃; Phytomenadione-d₃) is deuterium-labeled Vitamin K1 (HY-N0684) ^[1].

HY-N8383

Butyrolactone V	Parasite	Infection
Butyrolactone V is a butanolide compound. Butyrolactone V shows antiplasmodial activity against Plasmodium falciparum K1 with an IC₅₀ of 7.9 µg/ml ^[1].

HY-N5109

Cheilanthifoline	Parasite	Infection
Cheilanthifoline, an alkaloid, is isolated from Corydalis calliantha. Cheilanthifoline exhibits antiplasmodial activities against Plasmodium falciparum, with IC₅₀s of 0.90 μg/mL and 1.22 μg/mL for wild type (TM4) and multidrug resistant (K1) strains, respectively ^[1].

HY-106515

Tebuquine WR228258	Parasite	Infection
Tebuquine (WR228258), a 4-aminoquinoline, is a potent antimalarial agent. Tebuquine is active against the Chloroquine (HY-17589A) sensitive HB3 strain and the Chloroquine resistant K1 strain of Plasmodium falciparum with IC₅₀s of 0.9 nM and 20.8 nM, respectively ^[1].

HY-N10624

Koshidacin B	Parasite	Infection
Koshidacin B is an antiplasmodial cyclic tetrapeptide with antiplasmodial activity against *P. falciparum* FCR3 and K1 strain with IC₅₀ values of 0.89 and 0.83 μM, respectively. Koshidacin B suppresses malaria parasites in vivo, it can be used for the research of parasites infection ^[1].

HY-152614

Antimalarial agent 19	Parasite	Infection
Antimalarial agent 19 (compound 6e) is an antimalarial active agent. Antimalarial agent 19 has antimalarial activity for the blood stage of P. falciparum K1 and P. berghei with EC₅₀ values of 0.3 µM, 15.3 µM, respectively. Antimalarial agent 19 has good aqueous solubility, intestinal permeability and microsomal stability compared to gamhepathiopine ^[1].

HY-B0918

Chlorindione Chlophenadione; Indaliton; G-25766	VD/VDR	Cardiovascular Disease
Chlorindione (Chlophenadione) is a potent anticoagulant. Chlorindione also is a vitamin K1 antagonist ^[1].

HY-100332

CP 375	Biochemical Assay Reagents	Others
CP 375 is a Fe ³⁺ chelating agent, with a log K₁ value of 14.50.

HY-108003

MM 07	Apelin Receptor (APJ)	Cardiovascular Disease
MM 07 is a biased apelin receptor agonist, with a K_D of 300 nM in CHO-K1 cells and a K_D of 172 nM in human heart.

HY-P99888

Pimurutamab	EGFR	Others
Pimurutamab is a humanized IgG1-κ antibody targeting EGFR. Mainly expressed by CHO-K1 cells ^[1].

HY-N12700

Puberulic acid Ⅰ	Parasite	Infection
Puberulic acid Ⅰ possesses anti-malarial activity with an IC₅₀ value of 0.050 µM against Plasmodium falciparum K1 (chloroquine-resistant) ^[1].

HY-155354

Antimalarial agent 33	Parasite	Infection
Antimalarial agent 33 (compound 5g) has antiplasmodial activity against erythrocytic and hepatic stages of Plasmodium with an EC₅₀ of 1.1 μM for K1 P. falciparum strain. Antimalarial agent 33 demonstrats enhanced microsomal stability (T_1/2=29 min). Antimalarial agent 33 has no significant cytotoxicity against primary hepatocytes ^[1].

HY-B0918R

Chlorindione (Standard)	VD/VDR	Cardiovascular Disease
Chlorindione (Standard) is the analytical standard of Chlorindione. This product is intended for research and analytical applications. Chlorindione (Chlophenadione) is a potent anticoagulant. Chlorindione also is a vitamin K1 antagonist ^[1].

HY-126640

Phomoxanthone A	Parasite	Infection Cancer
Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis. Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC₅₀ is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL). Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC₅₀ is 0.99, 0.51 and 1.4 µg/mL, respectively ^[1].

HY-P99870

Eblasakimab ASLAN004; CSL-334; MK-6105	Interleukin Related	Others
Eblasakimab (ASLAN004; CSL-334) is a human IgG4 antibody that specifically targets IL13RA1 and is primarily expressed by CHO-K1 cells ^[1].

HY-P990009

Nisevokitug NIS-793	TGF-beta/Smad	Cancer
Nisevokitug (NIS-793) is a human, IgG2λ antibody targeting TGF-β (TGFB1/TGFB2). Nisevokitug is expressed by CHO-K1 cells ^[1].

HY-124104

Aldicarb sulfoxide	Drug Metabolite	Cardiovascular Disease Metabolic Disease
Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC₅₀ of 10 μM for both in zebrafish ^[1] .

HY-100962A

AG 99 Tyrphostin 46; Tyrphostin AG 99	Tyrosinase	Cancer
AG 99 (Tyrphostin 46), a tyrphostin derivative, is a tyrosine kinase inhibitor that increases sister chromatid exchange frequency in transformed CHO-K1 and primary CHE cells. AG 99 is promising for research of proliferative diseases ^[1].

HY-169339

Villalstonine	Parasite	Infection Cancer
Villalstonine is a bisindole alkaloid with various biological activities including anticancer, antimalarial, and antiamoebic activities. Villalstonine exhibits potent antiplasmodial activity against the multidrug-resistant K1 strain of P. falciparum with an IC₅₀ value of 0.27 μM ^[1].

HY-123335

L-796778	Somatostatin Receptor	Others
L-796778 is an agonist of the hsst3 receptor. In CHO-K1 cells expressing the hsst3 receptor, L-796778 is a partial agonist that inhibits forskolin (HY-15371)-stimulated cAMP production with an IC₅₀ value of 18 nM ^[1].

HY-170848

Antimalarial agent 48	Parasite	Infection
Antimalarial agent 48 (Compound 15a) is a triazine-class compound with antimalarial activity, showing inhibitory concentrations of 280 nM against Plasmodium falciparum K1 and 290 nM against Plasmodium falciparum FCR3. Antimalarial agent 48 is expected to be useful for research in the field of antimalarial infections ^[1].

HY-P5872

Jingzhaotoxin XI JZTX-XI	Sodium Channel	Neurological Disease
Jingzhaotoxin XI (JZTX-XI) is a sodium conductance inhibitor with an IC₅₀ of 124 nM. Jingzhaotoxin XI slows the fast inactivation (EC₅₀=1.18±0.2 μM) of Na_v1.5 expressed in Chinese hamster ovary (CHO-K1) cells ^[1].

HY-173157

Analgesic/antidepressant agent-1	iGluR	Neurological Disease Inflammation/Immunology
Analgesic/antidepressant agent-1 (Compound k1) is an orally active and BBB-penatrable N-acetamide ketamine derivative. Analgesic/antidepressant agent-1 has a strong binding affinity for the NMDA receptor, possesses analgesic, anti-inflammatory, and antidepressant activities, and has low psychomimetic activity ^[1].

HY-145379

Miaosporone A	Parasite Endogenous Metabolite	Infection
Miaosporone A, an angucyclic quinone, exhibits antimalarial activity against Plasmodium falciparum K1 and antibacterial activity against Mycobacterium tuberculosis with respective IC₅₀ values of 2.5 and 2.4 μM and displays cytotoxic activities against both cancerous (MCF-7 and NCI-H187) and nonmalignant (Vero) cells ^[1].

HY-124104S

Aldicarb sulfoxide-d3	Isotope-Labeled Compounds	Metabolic Disease
Aldicarb sulfoxide-d₃ is the deuterium labled Aldicarb sulfoxide (HY-124104). Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC₅₀ of 10 μM for both in zebrafish ^[1] .

HY-N8374

Pheanthine	Parasite	Infection
Pheanthine (Compound 2) is an antiplasmodial agent, that inhibits chloroquine-resistant Plasmodium falciparum K-1 (IC₅₀ is 0.8 μM) and chloroquine-sensitive P. falciparum strain NF54 A19A (IC₅₀ of 0.03 μM). Pheanthine exhibits low cytotoxicity in human lung fibrosblast (MRC-5, IC₅₀ is 11.2 μM) and macrophages (PMM, IC₅₀ is 8 μM) ^[1].

HY-117617

CAY10669	Histone Acetyltransferase	Cancer
CAY10669 (compound 6d) is an anacardic acid (HY-N2020) derivative that inhibits histone acetyltransferase PCAF with an IC₅₀ of 662 μM ^[1]. CAY10669 enhances the SAHA-induced acetylation in HEPG2 cells, exhibits cytotoxicity in zebrafish embryo, promotes transgene expression in CHO-K1 cells ^[1] .

HY-136895

AZ12672857	Prostaglandin Receptor	Cancer
AZ12672857 is an orally active inhibitor of EphB4 (IC₅₀=1.3 nM) and Src kinases. AZ12672857 shows good inhibition of proliferation of c-Src transfected 3T3 cells (IC₅₀=2 nM) as well as autophosphorylation of EphB4 in transfected CHO-K1 cells (IC₅₀=9 nM) ^[1].

HY-N1074

Warangalone Scandenolone	Parasite PKA	Infection Inflammation/Immunology
Warangalone is an anti-malarial compound which can inhibit the growth of both strains of parasite 3D7 (chloroquine sensitive) and K1 (chloroquine resistant) with IC₅₀s of 4.8 μg/mL and 3.7 μg/mL, respectively. Warangalone can also inhibit cyclic AMP-dependent protein kinase catalytic subunit (cAK) with an IC₅₀ of 3.5 μM.

HY-161247

5-HT2A antagonist 2	5-HT Receptor	Metabolic Disease
5HT2A antagonist 2 is an orally active, selective antagonist for 5HT_2A with IC₅₀ of 14 nM. 5-HT2A antagonist 2 exhibits good chemical, hepatocyte, and plasma stability, without significant cytotoxicity in cell lines VERO, HFL-1, L929, NIH3T3, CHO-K1 ^[1].

HY-P991114

Adezkibart	FLT3	Inflammation/Immunology
Adezkibart is a human monoclonal antibody immunosuppressant targeting the human FMS-like tyrosine kinase 3 ligand (FLT3LG) target. Adezkibart is found in the Chinese hamster ovary cell line CHO-K1, which binds to FLT3LG to block the relevant signaling pathway, inhibits the immune response, and exerts immunosuppressive activity. Adezkibart is promising for research of immune-related diseases ^[1].

HY-W107616

3,7,11,15-Tetramethyl-2-hexadecen-1-ol	Endogenous Metabolite	Others
3,7,11,15-Tetramethyl-2-hexadecen-1-ol can be used to synthesize vitamin E and vitamin E's precursor vitamin K1. 3,7,11,15-Tetramethyl-2-hexadecen-1-ol regulates transcription in cells through the transcription factor PPAR-alpha and the retinoid X receptor (RXR)43 ^[1].

HY-P4146

Survodutide BI 456906	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake ^[1].

HY-157892

Antimalarial agent 38	Parasite	Infection
Antimalarial agent 38 (Compound 1) exhibits activity against antiplasmodial, which inhibits Plasmodium falciparum D6 strain, chloroquine-sensitive Thai strain and chloroquine-resistant FcB1 strain and K1 strain, with IC₅₀s of 0.5, 13, 1 and 13 μM, respectively. Antimalarial agent 38 is non-cytotoxic for mammalian cells MCR58 (IC₅₀ >140 μM). Antimalarial agent 38 improves the survival rate of Plasmodium yoelii nigeriensis infected mouse model ^[1].

Cat. No.	Product Name	Target	Research Area

HY-P5964A

K1 peptide TFA	GABA Receptor	Neurological Disease
K1 peptide TFA is a high-affinity peptide ligand for GABAA receptor-associated protein (GABARAP) ^[1].

HY-108003

MM 07	Apelin Receptor (APJ)	Cardiovascular Disease
MM 07 is a biased apelin receptor agonist, with a K_D of 300 nM in CHO-K1 cells and a K_D of 172 nM in human heart.

HY-P4146

Survodutide BI 456906	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake ^[1].

HY-P4146A

Survodutide TFA BI 456906 TFA	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake ^[1].

HY-P5964

K1 peptide	GABA Receptor	Neurological Disease
K1 peptide is a high-affinity peptide ligand for GABAA receptor-associated protein (GABARAP) ^[1].

HY-P5204

Enterocin Hybrid 1 K1-EJ hybrid	Bacterial	Infection
Enterocin Hybrid 1 is a antibacterial agent, a antibacterial composition. Enterocin Hybrid 1 inhibits Vancomycin (HY-B0671)-resistant E. faecium, Staphylococcus haemoliticus ^[1].

HY-P5203

Enterocin K1 EntK1	Bacterial	Infection
Enterocin K1 (EntK1) is a bacteriocin. Enterocin K1 is a ribosomal synthetic peptide. Enterocin K1 specifically targets *Enterococcus faecalis* via the Eep protein on the bacterial membrane. Enterocin K1 displays a potent antibacterial activity against VRE. Enterocin K1 can be used for related studies of VRE infections ^[1].

HY-P5872

Jingzhaotoxin XI JZTX-XI	Sodium Channel	Neurological Disease
Jingzhaotoxin XI (JZTX-XI) is a sodium conductance inhibitor with an IC₅₀ of 124 nM. Jingzhaotoxin XI slows the fast inactivation (EC₅₀=1.18±0.2 μM) of Na_v1.5 expressed in Chinese hamster ovary (CHO-K1) cells ^[1].

HY-P0165B

Taspoglutide acetate ITM077 acetate; R1583 acetate; BIM51077 acetate	GLP Receptor	Metabolic Disease
Taspoglutide (R1583) acetate is an agonist of the glucagon-like peptide 1 receptor (GLP-1R) with an K_i value of 1.1 nM. Taspoglutide acetate induces cAMP accumulation in CHO-K1 cells expressing human GLP-1R (EC₅₀ = 0.06 nM). Taspoglutide acetate decreases blood levels of glucose and increases blood levels of insulin in a glucose tolerance test in Zucker diabetic obese rats. Taspoglutide acetate reduces blood levels of gastric inhibitory polypeptide (GIP), plasma levels of triglycerides, and body weight in the same model ^[1] .

HY-P10843

R4K1	Estrogen Receptor/ERR	Cancer
R4K1 is a cell-permeable stapled peptide. R4K1 binds to the estrogen receptor (ER) α with high affinity and inhibits its interaction with coactivators. R4K1 can enter breast cancer cells to regulate gene transcription and inhibit cell proliferation. R4K1 can be used in the study of cancer ^[1].

HY-P5896

Ala5-Galanin (2-11)	Neuropeptide Y Receptor	Neurological Disease
Ala5-Galanin (2-11) is a galanin receptor 2 (GAL₂R) specific agonist with a K_i of 258 nM ^[1].

HY-P4360

Suc-Ala-Phe-Lys-AMC	Fluorescent Dye	Others
Suc-Ala-Phe-Lys-AMC is a highly sensitive fluorogenic substrate for plasmin. Suc-Ala-Phe-Lys-AMC is also used for assaying gingipain K .

HY-P1925A

GO-203 TFA 2 Publications Verification	PI3K Reactive Oxygen Species Apoptosis	Cancer
GO-203 TFA is a potent *MUC1-C* oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the *PI3K-AKT-S6K1* pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice ^[1] .

Cat. No.	Product Name

HY-K2014

PEI Transfection Reagent 10+ Cited Publications
MCE PEI Transfection Reagent is designed based on 25 kDa PEI. It has high-efficiency, low-toxicity, strong-stability, and is suitable for many cell types, such as HEK-293、HEK-293T、CHO-K1、COS-1、COS-7、NIH/3T3、Sf9、HepG2 and HeLa et, even some hard-to-transfect cells. It can also be applied to large-scale recombinant protein expression and virus production.

Cat. No.	Product Name	Target	Research Area

HY-P990534

Anti-TSHR Antibody (K1-70) K1-70	TSH Receptor	Inflammation/Immunology
Anti-TSHR Antibody (K1-70) is a CHO-expressed human antibody that targets TSHR. Anti-TSHR Antibody (K1-70) has a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 143.54 kDa. For the isotype control of Anti-TSHR Antibody (K1-70), you can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P99870

Eblasakimab ASLAN004; CSL-334; MK-6105	Interleukin Related	Others
Eblasakimab (ASLAN004; CSL-334) is a human IgG4 antibody that specifically targets IL13RA1 and is primarily expressed by CHO-K1 cells ^[1].

HY-P990009

Nisevokitug NIS-793	TGF-beta/Smad	Cancer
Nisevokitug (NIS-793) is a human, IgG2λ antibody targeting TGF-β (TGFB1/TGFB2). Nisevokitug is expressed by CHO-K1 cells ^[1].

HY-P99006

Amatuximab MORab-009	Mesothelin	Cancer
Amatuximab (MORab-009) is a chimeric, humanized IgG1/k MAb that targets the cell surface mesothelin (MSLN). Mesothelin is a glycosylphosphatidyl inositol (GPI)-anchored membrane glycoprotein, which is present in a restricted set of normal adult tissues such as the mesothelium ^[1] .

HY-P99888

Pimurutamab	EGFR	Others
Pimurutamab is a humanized IgG1-κ antibody targeting EGFR. Mainly expressed by CHO-K1 cells ^[1].

HY-P991114

Adezkibart	FLT3	Inflammation/Immunology
Adezkibart is a human monoclonal antibody immunosuppressant targeting the human FMS-like tyrosine kinase 3 ligand (FLT3LG) target. Adezkibart is found in the Chinese hamster ovary cell line CHO-K1, which binds to FLT3LG to block the relevant signaling pathway, inhibits the immune response, and exerts immunosuppressive activity. Adezkibart is promising for research of immune-related diseases ^[1].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0684

Vitamin K1 4 Publications Verification Phylloquinone; Phytomenadione	Cardiovascular Disease Quinones Structural Classification Human Gut Microbiota Metabolites Microorganisms other families Classification of Application Fields Source classification Plants Endogenous metabolite Naphthalene Quinones Disease Research Fields	Endogenous Metabolite
Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-N7485

Gomisin K1 (-)-Gomisin K1	Structural Classification Source classification Lignans Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill.	Others
Gomisin K1 ((-)-Gomisin K1) is a lignan that exhibits anti-cancer activity. Gomisin K1 inhibits HeLa cell growth, with an IC₅₀ of 5.46 μM ^[1].

HY-N0684A

cis-Vitamin K1 cis-Phylloquinone; cis-Phytomenadione	Cardiovascular Disease Quinones Structural Classification Classification of Application Fields Source classification Endogenous metabolite Naphthalene Quinones Disease Research Fields	Endogenous Metabolite
Cis-Vitamin K1 is an endogenous metabolite of Vitamin K .

HY-N0684R

Vitamin K1 (Standard)	Quinones Structural Classification Human Gut Microbiota Metabolites Microorganisms other families Source classification Plants Endogenous metabolite Naphthalene Quinones	Endogenous Metabolite
Vitamin K1 (Standard) is the analytical standard of Vitamin K1. This product is intended for research and analytical applications. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-N8383

Butyrolactone V	Infection Structural Classification Monophenols Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Disease Research Fields	Parasite
Butyrolactone V is a butanolide compound. Butyrolactone V shows antiplasmodial activity against Plasmodium falciparum K1 with an IC₅₀ of 7.9 µg/ml ^[1].

HY-N5109

Cheilanthifoline	Infection Alkaloids Structural Classification Monophenols other families Classification of Application Fields Source classification Phenols Plants Isoquinoline Alkaloids Disease Research Fields	Parasite
Cheilanthifoline, an alkaloid, is isolated from Corydalis calliantha. Cheilanthifoline exhibits antiplasmodial activities against Plasmodium falciparum, with IC₅₀s of 0.90 μg/mL and 1.22 μg/mL for wild type (TM4) and multidrug resistant (K1) strains, respectively ^[1].

HY-N10624

Koshidacin B	Structural Classification Natural Products Microorganisms	Parasite
Koshidacin B is an antiplasmodial cyclic tetrapeptide with antiplasmodial activity against *P. falciparum* FCR3 and K1 strain with IC₅₀ values of 0.89 and 0.83 μM, respectively. Koshidacin B suppresses malaria parasites in vivo, it can be used for the research of parasites infection ^[1].

HY-N12700

Puberulic acid Ⅰ	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Parasite
Puberulic acid Ⅰ possesses anti-malarial activity with an IC₅₀ value of 0.050 µM against Plasmodium falciparum K1 (chloroquine-resistant) ^[1].

HY-126640

Phomoxanthone A	Quinones Structural Classification Microorganisms Anthraquinones Source classification	Parasite
Phomoxanthone A is a xanthone dimer, which can be isolated from Phomopsis. Phomoxanthone A exhibits antimalarial and antitubercular activities against Plasmodium falciparum (K1, multidrug-resistant strain, IC₅₀ is 0.11 µg/mL) and Mycobacterium tuberculosis (H37Ra strain, MIC is 0.50 µg/mL). Phomoxanthone A exhibits cytotoxicity in cells KB, BC-1 and Vero, IC₅₀ is 0.99, 0.51 and 1.4 µg/mL, respectively ^[1].

HY-169339

Villalstonine	Apocynaceae Structural Classification Alkaloids Other Alkaloids Source classification Alstonia angustifolia Wall. ex A.DC. Plants	Parasite
Villalstonine is a bisindole alkaloid with various biological activities including anticancer, antimalarial, and antiamoebic activities. Villalstonine exhibits potent antiplasmodial activity against the multidrug-resistant K1 strain of P. falciparum with an IC₅₀ value of 0.27 μM ^[1].

HY-145379

Miaosporone A	Infection Quinones Structural Classification Monophenols Classification of Application Fields Anthraquinones Source classification Phenols Endogenous metabolite Disease Research Fields	Parasite Endogenous Metabolite
Miaosporone A, an angucyclic quinone, exhibits antimalarial activity against Plasmodium falciparum K1 and antibacterial activity against Mycobacterium tuberculosis with respective IC₅₀ values of 2.5 and 2.4 μM and displays cytotoxic activities against both cancerous (MCF-7 and NCI-H187) and nonmalignant (Vero) cells ^[1].

HY-N8374

Pheanthine	Structural Classification Alkaloids Piperidine Alkaloids Triclisia gilletii (De Wild.) Staner Source classification Plants Menispermaceae	Parasite
Pheanthine (Compound 2) is an antiplasmodial agent, that inhibits chloroquine-resistant Plasmodium falciparum K-1 (IC₅₀ is 0.8 μM) and chloroquine-sensitive P. falciparum strain NF54 A19A (IC₅₀ of 0.03 μM). Pheanthine exhibits low cytotoxicity in human lung fibrosblast (MRC-5, IC₅₀ is 11.2 μM) and macrophages (PMM, IC₅₀ is 8 μM) ^[1].

HY-N1074

Warangalone Scandenolone	Structural Classification Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Isoflavones Erythrina variegata Linn.	Parasite PKA
Warangalone is an anti-malarial compound which can inhibit the growth of both strains of parasite 3D7 (chloroquine sensitive) and K1 (chloroquine resistant) with IC₅₀s of 4.8 μg/mL and 3.7 μg/mL, respectively. Warangalone can also inhibit cyclic AMP-dependent protein kinase catalytic subunit (cAK) with an IC₅₀ of 3.5 μM.

HY-W107616

3,7,11,15-Tetramethyl-2-hexadecen-1-ol	Structural Classification Natural Products Rudbeckia laciniata L. Source classification Plants Compositae	Endogenous Metabolite
3,7,11,15-Tetramethyl-2-hexadecen-1-ol can be used to synthesize vitamin E and vitamin E's precursor vitamin K1. 3,7,11,15-Tetramethyl-2-hexadecen-1-ol regulates transcription in cells through the transcription factor PPAR-alpha and the retinoid X receptor (RXR)43 ^[1].

HY-N6742

Borrelidin 1 Publications Verification Treponemycin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Anti-parasitic Antibacterial Disease Research Disease Research Fields	CDK Parasite Apoptosis Antibiotic
Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor which is a nitrile-containing macrolide antibiotic isolated from Streptomyces rochei ^[1]. Borrelidin is an inhibitor of Cdc28/Cln2 of the budding yeast, with an IC₅₀ of 24 μM . Borrelidin is a potent angiogenesis inhibitor, with an IC₅₀ of 0.8 nM. Borrelidin induces apoptosis in the tube-forming cells . Borrelidin has strong antimalarial activities, with IC₅₀s of 1.9 nM and 1.8 nM against K1 and FCR3 strains of Plasmodium falciparum, respectively .

HY-113513

5-HEPE	Microorganisms Source classification	Others
5(S)-HEPE is an active metabolite of eicosapentaenoic acid. It is formed from EPA by 5-lipoxygenase (5-LO). 5(S)-HEPE is an agonist of G protein-coupled receptor 119 (GPR119). It increases cAMP accumulation in CHO-K1 cells expressing human GPR119 when used at a concentration of 10 μM. 5(S)-HEPE increases glucose-induced insulin secretion from MING6 insulinoma pancreatic islets and glucagon-like peptide 1 (GLP-1) secretion from HuTu 80 adenocarcinoma cells when used at a concentration of 10 μM. Serum levels of 5(S)-HEPE are elevated in patients with hyperlipidemia.

HY-131591

Digalacturonic acid	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Digalacturonic acid is a metabolite of pectin or pectic acid. Digalacturonic acid can be used for the co-crystallization of enzymes such as proteinase K .

HY-N3260

Methyllucidone	Structural Classification Natural Products Source classification Plants Lauraceae	Reactive Oxygen Species Keap1-Nrf2 PI3K
Methyllucidone is a neuroprotective agent and an antioxidant that can be isolated from Lindera erythrocarpa Makino. Methyllucidone inhibits the ROS production, and activates antioxidant signaling pathways that include Nrf-2 and *PI3K* .

HY-N2357

Eudesmin (-)-Eudesmin; Eudesmine; (-)-Eudesmine	Infection Structural Classification Classification of Application Fields Magnoliaceae Source classification Lignans Metabolic Disease Magnolia Liliflora Desr. Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Ribosomal S6 Kinase (RSK)
Eudesmin ((-)-Eudesmin) impairs adipogenic differentiation via inhibition of *S6K1* signaling pathway. Eudesmin possesses diverse therapeutic effects, including anti-tumor, anti-inflammatory, and anti-bacterial activities ^[1].

HY-19312

3-Methyladenine Maximum Cited Publications 912 Publications Verification 3-MA	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	PI3K Autophagy Mitophagy Endogenous Metabolite
3-Methyladenine (3-MA) is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K .

HY-N3628

Coronarin A	Hedychium coronarium Koen. Structural Classification Natural Products Plants Zingiberaceae	mTOR Ribosomal S6 Kinase (RSK)
Coronarin A is an orally active natural compound that inhibits *mTORC1* and *S6K1* to increase IRS1 activity. Coronarin A shows anti-inflammatory activity and can also be used for type 2 diabetes mellitus research ^[1].

HY-N5005

Guanfu base H Atisinium chloride	Infection Alkaloids Classification of Application Fields Source classification Ranunculaceae Quinoline Alkaloids Aconitum carmichaeli Debx. Plants Disease Research Fields	Parasite
Guanfu base H (Atisinium chloride) is a diterpenoid alkaloid isolated from Aconitum coreanum and has antiplasmodial activity against the malarial *Plasmodium falciparum* strains TM4/8.2 (wild type) and K1CB1 with IC₅₀ values of 4 μM and 3.6 μM, respectively ^[1] .

HY-19312R

3-Methyladenine (Standard)	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	PI3K Autophagy Mitophagy Endogenous Metabolite
3-Methyladenine (Standard) is the analytical standard of 3-Methyladenine. This product is intended for research and analytical applications. 3-Methyladenine (3-MA) is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K .

Species:	Human (8) Mouse (6)
Tag:	GFP (1) His (11) Tag Free (1) GST (3) Flag (1)
Source:	HEK293 (7) Sf9 insect cells (5) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P70100

	Collectin-11/CL-K1 Protein, Human (HEK293, His) rHuCollectin-11/CL-K1, His; Collectin-11; Collectin Kidney Protein 1; CL-K1; COLEC11	Human	HEK293
	Collectin-11/CL-K1 is an important lectin in innate immunity, apoptosis, and embryogenesis that recognizes sugars presenting high mannose oligosaccharides with at least one terminal α-1,2-linked mannose epitope protein. It also recognizes fucosylated glycans and lipopolysaccharides. Collectin-11/CL-K1 Protein, Human (HEK293, His) is the recombinant human-derived Collectin-11/CL-K1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Collectin-11/CL-K1 Protein, Human (HEK293, His) is 246 a.a., with molecular weight of 30-35 kDa.

HY-P70067

	Collectin-11/CL-K1 Protein, Mouse (HEK293, His) rMuCollectin-11, His ; Collectin-11; Collectin Kidney Protein 1; CL-K1; Colec11	Mouse	HEK293
	Collectin-11/CL-K1 Protein is a secreted protein that activates tyrosine kinase receptors (EGFR, HER3) and ERK, JNK, and AKT signaling pathways to promote cell proliferation. Collectin-11/CL-K1 Protein plays an important role in innate immunity and apoptosis. Collectin-11/CL-K1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Collectin-11/CL-K1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Collectin-11/CL-K1 Protein, Mouse (HEK293, His) is 246 a.a., with molecular weight of 30-35 kDa.

HY-P76588

	S6K1/RPS6KB1 Protein, Human (sf9, GST) Ribosomal protein S6 kinase beta-1; S6K1; P70S6K1; p70 S6KA; RPS6KB1; STK14A	Human	Sf9 insect cells
	S6K1/RPS6KB1 is a kinase downstream of mTOR that regulates cellular processes critical for proliferation, growth, and cell cycle. It phosphorylates EIF4B, RPS6 and EEF2K and regulates protein synthesis by inhibiting the pro-apoptotic function of BAD, thereby enhancing cell survival. S6K1/RPS6KB1 Protein, Human (sf9, GST) is the recombinant human-derived S6K1/RPS6KB1 protein, expressed by Sf9 insect cells , with N-GST labeled tag.

HY-P78033

	Semaphorin-7A/SEMA7A Protein, Human (HEK293, His) Semaphorin-7A; Semaphorin-K1; Semaphorin-L; Sema L; CD108; CD108MGC126696; CDw108; H-SEMA-K1; H-Sema-L; JMH; MGC126692; Sema7A; SEMAK1; SEMAL	Human	HEK293
	Semaphorin-7A (SEMA7A) plays a key role in integrin-mediated signaling, affecting multiple cellular functions, including cell migration and immune responses. SEMA7A promotes focal adhesion complex formation, activates PTK2/FAK1 and induces phosphorylation of MAPK1 and MAPK3. Semaphorin-7A/SEMA7A Protein, Human (HEK293, His) is the recombinant human-derived Semaphorin-7A/SEMA7A protein, expressed by HEK293 , with C-8*His labeled tag.

HY-P78035

	Semaphorin-7A/SEMA7A Protein, Mouse (HEK293, His) Semaphorin-7A; Semaphorin-K1; Semaphorin-L; Sema L; CD108; CD108MGC126696; CDw108; H-SEMA-K1; H-Sema-L; JMH; MGC126692; Sema7A; SEMAK1; SEMAL	Mouse	HEK293
	Semaphorin-7A/SEMA7A proteins critically regulate integrin-mediated signaling, affecting cell migration and immune responses.It promotes focal adhesion complex formation, activates PTK2/FAK1, and leads to the phosphorylation of MAPK1 and MAPK3.Semaphorin-7A/SEMA7A Protein, Mouse (HEK293, His) is the recombinant mouse-derived Semaphorin-7A/SEMA7A protein, expressed by HEK293 , with C-His labeled tag.

HY-P78035A

	Semaphorin-7A/SEMA7A Protein, Mouse (HEK293, C-6His) Semaphorin-7A; Semaphorin-K1; Semaphorin-L; Sema L; CD108; CD108MGC126696; CDw108; H-SEMA-K1; H-Sema-L; JMH; MGC126692; Sema7A; SEMAK1; SEMAL	Mouse	HEK293
	Semaphorin-7A/SEMA7A proteins critically regulate integrin-mediated signaling, affecting cell migration and immune responses. It promotes focal adhesion complex formation, activates PTK2/FAK1, and leads to the phosphorylation of MAPK1 and MAPK3. Semaphorin-7A/SEMA7A Protein, Mouse (HEK293, C-6His) is the recombinant mouse-derived Semaphorin-7A/SEMA7A, expressed by HEK293 , with C-6*His labeled tag. ,

HY-P70302

	Kallikrein-1 Protein, Mouse (HEK293, His) rMuKallikrein-1, His ; Glandular kallikrein K1; KAL-B; Renal kallikrein; Tissue kallikrein-6; mGK-6	Mouse	HEK293
	Kallikrein-1 protein is a member of the glandular kallikrein family and plays a vital role in enzyme activity by cleaving the Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin..This proteolysis is critical for the production of bradykinin, a bioactive peptide involved in multiple physiological processes, including blood pressure regulation, inflammation, and vascular permeability.Kallikrein-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Kallikrein-1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P701835

	VKOR1 Protein, Human (HEK293, GFP, His) VKORC1; Vitamin K epoxide reductase complex subunit 1; Vitamin K1 2; 3-epoxide reductase subunit 1	Human	HEK293
	As the catalytic subunit of the VKOR complex, the VKOR1 protein is crucial in vitamin K metabolism and is essential for the reduction of inactive vitamin K 2,3-epoxide to the active form. This process is critical for γ-carboxylation of proteins and is particularly important for blood coagulation and the synthesis of coagulation factors. VKOR1 Protein, Human (HEK293, GFP, His) is the recombinant human-derived VKOR1 protein, expressed by HEK293 , with C-10*His, GFP labeled tag. The total length of VKOR1 Protein, Human (HEK293, GFP, His) is 163 a.a., .

HY-P702742

	MAP4K1 Protein, Human (sf9) MAP4K1; mitogen-activated protein kinase kinase kinase kinase 1	Human	Sf9 insect cells
	MAP4K1 Protein, Human (sf9) is the recombinant human-derived MAP4K1, expressed by Sf9 insect cells , with tag Free labeled tag. ,

HY-P703585

	MAP2K1 Protein, Human (Sf9, Flag) MEK1; PRKMK1	Human	Sf9 insect cells
	MAP2K1 Protein, Human (Sf9, Flag) is the recombinant human-derived MAP2K1, expressed by Sf9 insect cells , with Flag labeled tag. ,

HY-P77427

	IP6K1/IHPK1 Protein, Human (sf9, His-GST) Inositol hexakisphosphate kinase 1; InsP6 kinase 1; IHPK1; KIAA0263	Human	Sf9 insect cells
	IP6K1, also known as the IHPK1 protein, plays a crucial role in cell signaling by catalyzing the conversion of inositol hexaphosphate (InsP6) to inositol diphosphate pentaphosphate (InsP7/PP-InsP5). In addition, this enzyme is also involved in the conversion of 1,3,4,5,6-pentaphosphate (InsP5) to PP-InsP4. IP6K1/IHPK1 Protein, Human (sf9, His-GST) is the recombinant human-derived IP6K1/IHPK1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of IP6K1/IHPK1 Protein, Human (sf9, His-GST) is 441 a.a., with molecular weight of ~88 kDa.

HY-P73825

	MEK1 Protein, Mouse (sf9, His-GST) Dual specificity mitogen-activated protein kinase kinase 1; MAPKK 1; MEK 1; Map2K1	Mouse	Sf9 insect cells
	The MEK1 protein is a dual-specificity kinase that plays a crucial role in the MAP kinase pathway.MEK1 regulates various cellular processes such as growth, adhesion, survival, and differentiation, as well as transcription, metabolism, and cytoskeletal rearrangements.MEK1 Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived MEK1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P70931

	MAPKSP1 Protein, Human (His) Ragulator Complex Protein LAMTOR3; Late Endosomal/Lysosomal Adaptor and MAPK and MTOR Activator 3; MEK-Binding Partner 1; Mp1; Mitogen-Activated Protein Kinase Kinase 1-Interacting Protein 1; Mitogen-Activated Protein Kinase Scaffold Protein 1; LAMTOR3; MAP2K1IP	Human	E. coli
	The MAPKSP1 protein, also known as porphobilinogen deaminase (HMBS), is crucial in the heme biosynthetic pathway and catalyzes the sequential polymerization of four porphobilinogen molecules to form hydroxymethyl bixane. The process begins with the assembly of the dipyrromethane cofactor of porphobilinogen or preuroporphyrinogen. MAPKSP1 Protein, Human (His) is the recombinant human-derived MAPKSP1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of MAPKSP1 Protein, Human (His) is 124 a.a., with molecular weight of ~15.0 kDa.

HY-P700593

	MAP3K1 Protein, Mouse (His) MEKK; MEKK1; SRXY6; MEKK 1; MAPKKK1; MAP/ERK kinase kinase 1; MAPK/ERK kinase kinase 1; MEK kinase 1; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase; mitogen-activated protein kinase kinase kinase 1	Mouse	E. coli
	MAP3K1 is a key component of the protein kinase signal transduction cascade and plays a crucial role in cell signaling pathways.Through its kinase activity, MAP3K1 coordinates the activation of the ERK and JNK kinase pathways by phosphorylating MAP2K1 and MAP2K4.MAP3K1 Protein, Mouse (His) is the recombinant mouse-derived MAP3K1 protein, expressed by E.coli , with N-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-N0684S

Vitamin K1-d7
Vitamin K1-d₇ is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1][2].

HY-N0684AS

cis-Vitamin K1-d7
cis-Vitamin K1-d₇ is the deuterium labeled cis-Vitamin K1, is an endogenous metabolite of Vitamin K .

HY-113164S

Vitamin K1 2,3-epoxide-d7
Vitamin K1 2,3-epoxide-d₇ is the deuterium labeled Vitamin K1 2,3-epoxide[1].

HY-N0684S1

Vitamin K1-d4
Vitamin K1-d₄ is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1].

HY-N0684S3

Vitamin K1-13C6
Vitamin K1- ¹³C₆ is the ¹³C-labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-N0684S4

Vitamin K1-d3
Vitamin K1-d₃ (Phylloquinone-d₃; Phytomenadione-d₃) is deuterium-labeled Vitamin K1 (HY-N0684) ^[1].

HY-124104S

Aldicarb sulfoxide-d3
Aldicarb sulfoxide-d₃ is the deuterium labled Aldicarb sulfoxide (HY-124104). Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC₅₀ of 10 μM for both in zebrafish ^[1] .

HY-10042S

Odanacatib-d4
Odanacatib-d4 is the deuterium labeled Odanacatib (HY-10042). Odanacatib is a potent and selective inhibitor of cathepsin K, with an IC₅₀ of 0.2 nM for human cathepsin K .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80580

	CaMK1 Antibody CaM K1; CaM KI; CaMK 1; CAMK I; CaMK1 alpha; CAMK1 PEN; CaMKI alpha	WB	Mouse, Rat
	CaMK1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 41 kDa, targeting to CaMK1. It can be used for WB assays with tag free, in the background of Mouse, Rat.

HY-P82920

	Cytokeratin 1 Antibody (YA2665) 67 kDa cytokeratin; CK1; EHK; Epidermolytic hyperkeratosis 1; EPPK; Hair alpha protein; K1; Keratin; KRT 1; KRT1A; NEPPK; type II cytoskeletal 1; Type-II keratin Kb1	WB	Human, Mouse, Rat
	Cytokeratin 1 Antibody (YA2665) is a non-conjugated IgG antibody, targeting Cytokeratin 1, with a predicted molecular weight of 66 kDa (observed band size: 66 kDa). Cytokeratin 1 Antibody (YA2665) can be used for WB experiment in human, mouse, rat background.

HY-P81748

	Cytokeratin 15 Antibody (YA1493) CK-15; CK15; cytokeratin15; K15; K1C15; K1CO; keratin 15; Keratin-15; keratin-15; beta; KRT15; KRTB; type I cytoskeletal 15	WB, IHC-P, ICC/IF, FC	Human, Mouse
	Cytokeratin 15 Antibody (YA1493) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1493), targeting Cytokeratin 15, with a predicted molecular weight of 49 kDa. Cytokeratin 15 Antibody (YA1493) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse background.

HY-P81183

	Cytokeratin 19 Antibody 40 kDa keratin intermediate filament; CK 19; cK19; CK19; CK-19; KRT19; Cytokeratin19; Cytokeratin-19; K19; K1cs; Keratin 19; Keratin-19; Keratin type I 40 kD; Keratin type i 40kD; Keratin type I cytoskeletal 19; krt19; mgc15366; K1C19_HUMAN; Keratin, type I cytoskeletal 19; Keratin, type I, 40 kd.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human
	Cytokeratin 19 Antibody is an unconjugated, approximately 44 kDa, rabbit-derived, anti-Cytokeratin 19 polyclonal antibody. Cytokeratin 19 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human and predicted: mouse, rat, chicken, dog, pig, cow, horse, rabbit background without labeling.

HY-P81183A

	Cytokeratin 19 Antibody(PBS only) 40 kDa keratin intermediate filament; CK 19; cK19; CK19; CK-19; KRT19; Cytokeratin19; Cytokeratin-19; K19; K1cs; Keratin 19; Keratin-19; Keratin type I 40 kD; Keratin type i 40kD; Keratin type I cytoskeletal 19; krt19; mgc15366; K1C19_HUMAN; Keratin, type I cytoskeletal 19; Keratin, type I, 40 kd.	WB, IHC-P, IHC-F, ICC/IF, FC, ELISA	Human, Mouse
	Cytokeratin 19 Antibody is an unconjugated, approximately 44 kDa, rabbit-derived, anti-Cytokeratin 19 polyclonal antibody. Cytokeratin 19 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, and predicted: rat, chicken, dog, pig, cow, horse, rabbit background without labeling.

HY-P81181

	CK18 Antibody 1 Publications Verification K1C18_HUMAN; Keratin, type I cytoskeletal 18; KRT18; CYK18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18 (CK-18); Keratin-18 (K18); PIG46; Keratin 18	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse, Rat
	CK18 Antibody is an unconjugated, approximately 48 kDa, rabbit-derived, anti-CK18 polyclonal antibody. CK18 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, mouse, rat, and predicted: dog, pig, cow, horse, rabbit background without labeling.

HY-P83053

	DAP Kinase 1 Antibody (YA2798) DAK1; DAP K1; DAP kinase 1; DAPK 1; DAPK; DAPK1; DAPK1_HUMAN; Death Associated Protein Kinase 1; Death-associated protein kinase 1	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	DAP Kinase 1 Antibody (YA2798) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2798), targeting DAP Kinase 1, with a predicted molecular weight of 160 kDa (observed band size: 160 kDa). DAP Kinase 1 Antibody (YA2798) can be used for WB, IHC-P, ICC/IF experiment in human, mouse, rat background.

HY-P81899

	PIP5K1C Antibody (YA1644) AI115456; AI835305; Pip5kIgamma	WB, IP	Human, Mouse
	PIP5K1C Antibody (YA1644) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1644), targeting PIP5K1C, with a predicted molecular weight of 72 kDa (observed band size: 90,87 kDa). PIP5K1C Antibody (YA1644) can be used for WB, IP experiment in human, mouse background.

HY-P83487

	Semaphorin 7A Antibody (YA3232) JMH; CD108; SEMAL; CDw108; SEMAK1; H-Sema-L; H-SEMA-K1	WB, IHC-P, IP	Human
	Semaphorin 7A Antibody (YA3232) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3232), targeting Semaphorin 7A, with a predicted molecular weight of 75 kDa (observed band size: 75 kDa). Semaphorin 7A Antibody (YA3232) can be used for WB, IHC-P, IP experiment in human background.

HY-P81250

	Cytokeratin 19 Antibody (YA924) 40 kDa keratin intermediate filament; CK 19; cK19; CK19; CK-19; KRT19; Cytokeratin19; Cytokeratin-19; K19; K1cs; Keratin 19; Keratin-19; Keratin type I 40 kD; Keratin type i 40kD; Keratin type I cytoskeletal 19; krt19; mgc15366; K1C19_HUMAN; Keratin, type I cytoskeletal 19; Keratin, type I, 40 kd	WB, IHC-P, IHC-F, ICC/IF	Human
	Cytokeratin 19 Antibody is an unconjugated, approximately 44 kDa, mouse-derived, anti-Cytokeratin 19 monoclonal antibody. Cytokeratin 19 Antibody can be used for: WB,IHC-F,IHC-P,ICC/IF expriments in human background without labeling.

HY-P81209

	S6K1 Antibody 70 kDa ribosomal protein S6 kinase 1 antibody; KS6B1_HUMAN antibody; p70 alpha antibody; P70 beta 1 antibody p70 ribosomal S6 kinase alpha antibody; p70 ribosomal S6 kinase beta 1 antibody; p70 S6 kinase alpha antibody; P70 S6 Kinase antibody; p70 S6 kinase, alpha 1 antibody; p70 S6 kinase, alpha 2 antibody; p70 S6K antibody; p70 S6K-alpha antibody; p70 S6KA antibody; p70(S6K) alpha antibody; p70(S6K)-alpha antibody; p70-alpha antibody; p70-S6K 1 antibody; p70-S6K antibody; P70S6K antibody; P70S6K1 antibody; p70S6Kb antibody; PS6K antibody; Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody; Ribosomal protein S6 kinase beta 1 antibody; Ribosomal protein S6 kinase beta-1 antibody; Ribosomal protein S6 kinase I antibody; RPS6KB1 antibody; S6K antibody; S6K-beta-1 antibody; S6K1 antibody; Serine/threonine kinase 14 alpha antibody; Serine/threonine-protein kinase 14A antibody; STK14A antibody	WB, ELISA, IHC-P, IHC-F, ICC/IF	Human, Rat
	S6K1 Antibody is an unconjugated, approximately 59 kDa, rabbit-derived, anti-S6K1 monoclonal antibody. S6K1 Antibody can be used for: WB, ICC/IF, IP expriments in human, rat, mouse background without labeling.

HY-P82336

	Phospho-Glutamate Receptor 1 (AMPA Subtype) (Ser845) Antibody (YA2081) GRIA1; GLUH1; GLUR1; Glutamate receptor 1; GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic; AMPA 1; GluA1	WB	Human, Rat
	Phospho-Glutamate Receptor 1 (AMPA Subtype) (Ser845) Antibody (YA2081) is a non-conjugated IgG antibody, targeting Phospho-Glutamate Receptor 1 (AMPA Subtype) (Ser845), with a predicted molecular weight of 102 kDa (observed band size: 102 kDa). Phospho-Glutamate Receptor 1 (AMPA Subtype) (Ser845) Antibody (YA2081) can be used for WB experiment in human, rat background.

HY-P80832

	Phospho-MEK1 (Ser298) Antibody MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1	WB, ICC/IF	Human, Mouse, Rat
	Phospho-MEK1 (Ser298) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 43 kDa, targeting to Phospho-MEK1 (Ser298). It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80833

	Phospho-MEK1 (Thr292) Antibody MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1	WB	Mouse, Rat
	Phospho-MEK1 (Thr292) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 43 kDa, targeting to Phospho-MEK1 (Thr292). It can be used for WB assays with tag free, in the background of Mouse, Rat.

HY-P83702

	Cytokeratin 17 Antibody (YA3438) 39.1 antibody; CK 17 antibody; CK17 antibody; CK-17 antibody; Cytokeratin-17 antibody; K17 antibody; K1C17_HUMAN antibody; Keratin 17 antibody; keratin 17 epitope S1 antibody; keratin 17 epitope S2 antibody; keratin 17 epitope S4 antibody; Keratin 17, type I antibody; Keratin antibody; Keratin type I cytoskeletal 17 antibody; keratin, type i cytoskeletal 17 [version 1] antibody; Keratin-17 antibody; KRT17 antibody; PC antibody; PC2 antibody; PCHC1 antibody; type I cytoskeletal 17 antibody;	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	Cytokeratin 17 Antibody (YA3438) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3438), targeting Cytokeratin 17, with a predicted molecular weight of 48 kDa (observed band size: 48 kDa). Cytokeratin 17 Antibody (YA3438) can be used for WB, IF-Cell, IF-Tissue, IHC-P experiment in human, Mouse, Rat background.

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Cat. No.	Product Name		Classification

HY-152233

Reverse transcriptase-IN-4		Azide
Reverse transcriptase-IN-4 (compound F10) is a potent and selective non-nucleoside reverse transcriptase (NNRT) inhibitor with an EC₅₀ value of 0.053 μM for wild-type HIV-1 and an EC₅₀ value of 0.26 μM for HIV-1 mutant E138K . Reverse transcriptase-IN-4 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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