Search Result
Results for "
PEG8
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-153962
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Drug-Linker Conjugates for ADC
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Cancer
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SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 is a Drug-Linker Conjugate for ADC. SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 consists of the anti-cancer agent SN38 (HY-13704) and a linker Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 (HY-131157). SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 can be used for synthesis of ADCs . SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-126893
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PROTAC Linkers
ADC Linker
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Cancer
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Bis-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-133053
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Hydroxy-PEG8-acid
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PROTAC Linkers
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Cancer
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HO-PEG8-CH2CH2COOH (Hydroxy-PEG8-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-W019798
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ADC Linker
PROTAC Linkers
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Cancer
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NH2-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . NH2-PEG8-acid also is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-139322
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Biochemical Assay Reagents
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Others
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PEG-8 laurate is a single chain surfactant. PEG-8 laurate reduces the skin barrier, and acts as a penetration enhancer. PEG-8 laurate can be used to synthesize elastic vesicles .
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- HY-130555
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PROTAC Linkers
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Cancer
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PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-101530A
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PEG 8 stearate
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Biochemical Assay Reagents
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Others
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Polyoxyl 8 stearate can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-141161A
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PROTAC Linkers
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Cancer
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(S)-TCO-PEG8-acid is a click chemistry PEG linker with a terminal carboxylic acid(COOH) group. The terminal carboxylic acid is reactive with primary amine groups to form a stable amide bond. (S)-TCO-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. (S)-TCO-PEG8-acid is longer than (S)-TCO-PEG3-acid .
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- HY-W096114
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PROTAC Linkers
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Cancer
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Acid-PEG8-S-S-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-D2107
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Fluorescent Dye
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Others
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TAMRA-PEG8-NHS is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-NHS contains NHS groups that react with ammonia to form ester bonds.
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- HY-117031
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ADC Linker
PROTAC Linkers
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Cancer
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m-PEG8-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-130377
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG8-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D2110
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Fluorescent Dye
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Others
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TAMRA-PEG8-COOH is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
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- HY-130379
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ADC Linker
PROTAC Linkers
Bacterial
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Infection
Cancer
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Propargyl-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria . Propargyl-PEG8-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130376
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG8-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130165
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- HY-156379
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- HY-140268
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PROTAC Linkers
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Cancer
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DBCO-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG8-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-W019799
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ADC Linker
PROTAC Linkers
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Cancer
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Amino-PEG8-Boc is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG8-Boc is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-D2141
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Fluorescent Dye
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Others
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Cy3-PEG8-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 8 PEG units. Cy3-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-135090
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PROTAC Linkers
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Cancer
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Tos-PEG8-m is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-d). Tos-PEG8-m is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277) .
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- HY-156388
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PROTAC Linkers
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Cancer
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SCO-PEG8-COOH is a PROTAC linker and belongs to the PEG class. SCO-PEG8-COOH contains SCO and COOH that can be covalently combined with amino groups, respectively. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
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- HY-130334
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PROTAC Linkers
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Cancer
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Mal-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-133294
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HS-PEG8-OH
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PROTAC Linkers
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Cancer
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Thiol-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-D2159
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Fluorescent Dye
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Others
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Cy5-PEG8-Tetrazin is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG8-Tetrazin contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-D2114
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Fluorescent Dye
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Others
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TAMRA-PEG8-Alkyne is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-W580022
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E3 Ligase Ligand-Linker Conjugates
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Cancer
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Pomalidomide-5'-PEG8-C2-COOH is an E3 Ligase Ligand-Linker Conjugates, consisting of Pomalidomide (HY-10984) and a linker. Pomalidomide-5'-PEG8-C2-COOH can be used for synthesis of PROTACs .
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- HY-141161B
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ADC Linker
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Cancer
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(R)-TCO-PEG8-acid is an ADC linker containing 8 PEG units. (R)-TCO-PEG8-acid can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
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- HY-141161
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PROTAC Linkers
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Cancer
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TCO-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-141383
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PROTAC Linkers
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Cancer
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Bromoacetamido-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130542
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PROTAC Linkers
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Cancer
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Thiol-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141333
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PROTAC Linkers
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Cancer
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Lipoamido-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140395
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PROTAC Linkers
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Cancer
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Aminooxy-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141265
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PROTAC Linkers
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Cancer
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Methyltetrazine-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-132015
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PROTAC Linkers
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Cancer
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Benzyl-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130200
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PROTAC Linkers
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Cancer
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NH2-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-115414
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PROTAC Linkers
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Cancer
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Bis-propargyl-PEG8 (compound 16e) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130374
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PROTAC Linkers
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Cancer
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Propargyl-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG8-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140273
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PROTAC Linkers
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Cancer
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DBCO-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG8-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140065
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PROTAC Linkers
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Cancer
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endo-BCN-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG8-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140316
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PROTAC Linkers
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Cancer
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m-PEG8-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG8-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-130910
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PROTAC Linkers
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Cancer
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Propargyl-PEG8-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG8-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-156385
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PROTAC Linkers
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Cancer
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SCO-PEG8-NHS SCO is a PROTAC linker and belongs to the PEG class. SCO-PEG8-NHS SCO contains SCO and NHS esters that can be covalently bound to amino groups, respectively. SCO is often used to react with amino acid residues of proteins or peptides, particularly lysine.
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- HY-156309
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Fluorescent Dye
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Others
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Coumarin-PEG8-tetrazine is a dye derivative of Coumarin (HY-N0709) containing 8 PEG units. Coumarin-PEG8-tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-126887
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PROTAC Linkers
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Cancer
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Mal-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-140454
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ADC Linker
PROTAC Linkers
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Cancer
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Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG8-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-141397
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Methyl-PEG8-t-butyl ester
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PROTAC Linkers
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Cancer
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m-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-156477
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ADC Linker
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Cancer
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Me-Tet-PEG8-NHBoc is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
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- HY-49484
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ADC Linker
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Cancer
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EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable ADC linker.
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- HY-130182
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ADC Linker
PROTAC Linkers
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Cancer
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Propargyl-PEG8-NH2 (compound 3b) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NH2 is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-130662
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PROTAC Linkers
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Cancer
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Hydroxy-PEG8-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-138711
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PROTAC Linkers
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Cancer
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Benzyl-PEG8-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- HY-149416
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Drug-Linker Conjugates for ADC
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Cancer
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Mal-PEG8-Val-Ala-PAB-SB-743921 (Compound D7) is a Drug-Linker Conjugates for ADC. Mal-PEG8-Val-Ala-PAB-SB-743921 consists of KSP inhibitor SB-743921 (HY-14661) and a linker. Mal-PEG8-Val-Ala-PAB-SB-743921 can be used for synthesis of ADCs .
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- HY-140492
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PROTAC Linkers
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Cancer
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Biotin-PEG8-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141156
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Drug-Linker Conjugates for ADC
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Cancer
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Mal-PEG8-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Mal-PEG8-Val-Cit-PAB-MMAE contains a cleavable ADC linker and a potent tubulin inhibitor MMAE (HY-15162) .
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- HY-148380
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- HY-156758
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Drug-Linker Conjugates for ADC
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Cancer
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Mal-PEG8-Val-Cit-PAB-MMAF is a drug-linker conjugate for ADC. Mal-PEG8-Val-Cit-PAB-MMAF contains a cleavable ADC linker and a potent tubulin inhibitor MMAE (HY-15162) .
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- HY-148380A
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- HY-141169B
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ADC Linker
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Cancer
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(R)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (R)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
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- HY-140070
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PROTAC Linkers
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Cancer
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endo-BCN-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG8-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-140883
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PROTAC Linkers
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Cancer
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Boc-NH-PEG8-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG8-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-135932
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PROTAC Linkers
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Cancer
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m-PEG8-O-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG8-O-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D2116
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Fluorescent Dye
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Others
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TAMRA-PEG8-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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- HY-126497
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ADC Linker
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Cancer
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LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs) .
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- HY-126919
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PROTAC Linkers
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Cancer
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THP-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141169
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PROTAC Linkers
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Cancer
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TCO-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-141181
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PROTAC Linkers
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Cancer
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TCO-PEG8-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-141189
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PROTAC Linkers
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Cancer
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TCO-PEG8-TCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
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- HY-141330
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PROTAC Linkers
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Cancer
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m-PEG8-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140385
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PROTAC Linkers
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Cancer
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Ms-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140982
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PROTAC Linkers
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Cancer
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m-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140956
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- HY-140970
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PROTAC Linkers
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Cancer
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Mal-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140369
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PROTAC Linkers
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Cancer
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Tos-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141228
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PROTAC Linkers
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Cancer
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THP-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141173
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PROTAC Linkers
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Cancer
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TCO-PEG8-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130148
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PROTAC Linkers
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Cancer
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m-PEG8-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-133212
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PROTAC Linkers
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Cancer
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Mal-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-130348
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PROTAC Linkers
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Cancer
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OPSS-PEG8-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141368
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PROTAC Linkers
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Cancer
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Bromo-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141389
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PROTAC Linkers
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Cancer
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Bromoacetamido-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140400
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PROTAC Linkers
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Cancer
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Aminooxy-PEG8-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140891
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PROTAC Linkers
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Cancer
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Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-141270
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PROTAC Linkers
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Cancer
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Methyltetrazine-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140443
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PROTAC Linkers
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Cancer
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Cbz-aminooxy-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140950
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- HY-141273
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PROTAC Linkers
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Cancer
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Methyltetrazine-PEG8-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140894
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PROTAC Linkers
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Cancer
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Biotin-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-132013
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PROTAC Linkers
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Cancer
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Benzyl-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-132016
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PROTAC Linkers
|
Cancer
|
Benzyl-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132072
-
|
PROTAC Linkers
|
Cancer
|
THP-PEG8-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-134741
-
|
PROTAC Linkers
|
Cancer
|
Benzyl-PEG8-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138335
-
|
PROTAC Linkers
|
Cancer
|
Boc-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138337
-
|
PROTAC Linkers
|
Cancer
|
MS-PEG8-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138339
-
|
PROTAC Linkers
|
Cancer
|
Benzyl-PEG8-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138340
-
|
PROTAC Linkers
|
Cancer
|
THP-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138490
-
|
PROTAC Linkers
|
Cancer
|
Iodoacetyl-PEG8-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096066
-
|
PROTAC Linkers
|
Cancer
|
Benzyl-PEG8-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096099
-
|
PROTAC Linkers
|
Cancer
|
Nonylbenzene-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W096107
-
|
PROTAC Linkers
|
Cancer
|
Benzyl-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141169A
-
|
ADC Linker
|
Cancer
|
(S)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (S)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-W040236
-
-
- HY-130659
-
|
PROTAC Linkers
|
Cancer
|
Amino-PEG8-amine is a PEG-based (8 units) PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-48692
-
|
ADC Linker
|
Cancer
|
Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable ADC linker.
|
-
- HY-130184
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140264
-
|
PROTAC Linkers
|
Cancer
|
NH-bis(m-PEG8) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-156324
-
|
ADC Linker
|
Cancer
|
BCN-exo-PEG8-NHS is an ADC Linker containing 8 PEG units. BCN-exo-PEG8-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-140899
-
|
PROTAC Linkers
|
Cancer
|
Biotin-PEG8-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-156301A
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG8-NH2 (hydrochloride) is an ADC Linker containing 2 PEG units. Me-Tet-PEG8-NH2 (hydrochloride) can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-132252
-
MP-PEG8-Val-Ala-PABC; MP-PEG8-VA-PABC
|
ADC Linker
|
Cancer
|
Mal-PEG8-Val-Ala-PABC is a cleavable Tesirine linker used in the synthesis of Tesirine, a agent-linker conjugate for ADC .
|
-
- HY-W040133
-
|
PROTAC Linkers
|
Cancer
|
Mal-amido-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141192
-
|
PROTAC Linkers
|
Cancer
|
N-Boc-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130209
-
|
PROTAC Linkers
|
Cancer
|
S-Acetyl-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-126880
-
|
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140224
-
|
PROTAC Linkers
|
Cancer
|
Amino-PEG8-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140979
-
|
PROTAC Linkers
|
Cancer
|
Mal-amido-PEG8-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140513
-
|
PROTAC Linkers
|
Cancer
|
Active-mono-sulfone-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140503
-
|
PROTAC Linkers
|
Cancer
|
m-PEG8-ethoxycarbonyl-propanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141111
-
|
PROTAC Linkers
|
Cancer
|
m-PEG8-ethoxycarbonyl--NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140444
-
|
PROTAC Linkers
|
Cancer
|
Cbz-aminooxy-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141114
-
|
PROTAC Linkers
|
Cancer
|
m-PEG8-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132044
-
|
PROTAC Linkers
|
Cancer
|
Benzyl-PEG8-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132080
-
|
PROTAC Linkers
|
Cancer
|
Bis-PEG8-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-132084
-
|
PROTAC Linkers
|
Cancer
|
Bromoacetamido-PEG8-t-butyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138447
-
|
PROTAC Linkers
|
Cancer
|
Mal-NH-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133063
-
|
ADC Linker
PROTAC Linkers
|
Cancer
|
Fmoc-NH-PEG8-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-NH-PEG8-CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-147271
-
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
Mal-PEG8-Val-Ala-PAB-Exatecan (Compound 9b) is an antibody-drug conjugate linker (ADC linker) that binds to Nectin-4 polypeptides conjugated to chemotherapeutic agents. Mal-PEG8-Val-Ala-PAB-Exatecan can be used for cancer research .
|
-
- HY-140635
-
|
PROTAC Linkers
|
Cancer
|
Ald-CH2-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Ald-CH2-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-131088
-
|
Drug-Linker Conjugates for ADC
|
Cancer
|
N3-PEG8-Phe-Lys-PABC-Gefitinib is a agent-linker conjugate for ADC with potent antitumor activity by using the anti-tumor agent, Gefitinib (orally active EGFR tyrosine kinase inhibitor), linked via the cleavable linker N3-PEG8-Phe-Lys-PABC. N3-PEG8-Phe-Lys-PABC-Gefitinib is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-135943
-
|
PROTAC Linkers
|
Cancer
|
NH2-PEG8-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-W019793
-
-
- HY-133311
-
HO-PEG8-CH2COOtBu
|
PROTAC Linkers
|
Cancer
|
Hydroxy-PEG8-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-145943
-
-
- HY-156312
-
|
ADC Linker
|
Cancer
|
Me-Tet-PEG8-Maleimide is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-141290
-
|
PROTAC Linkers
|
Cancer
|
Bis-(m-PEG8-amido)-hexanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140378
-
|
PROTAC Linkers
|
Cancer
|
t-Boc-Aminooxy-PEG8-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-140424
-
|
PROTAC Linkers
|
Cancer
|
t-Boc-Aminooxy-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130204
-
|
PROTAC Linkers
|
Cancer
|
m-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140773
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG8-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140799
-
|
PROTAC Linkers
|
Cancer
|
Azide-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG8-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140216
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140860
-
|
PROTAC Linkers
|
Cancer
|
Trityl-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Trityl-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140815
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG8-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-132010
-
|
PROTAC Linkers
|
Cancer
|
Benzyl-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Benzyl-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-132055
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG8-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-THP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138437
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG8-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-TFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138706
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138708
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG8-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG8-NHBoc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130137
-
|
PROTAC Linkers
|
Cancer
|
m-PEG8-C10-phosphonic acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-130145
-
|
PROTAC Linkers
|
Cancer
|
m-PEG8-CH2COOH is a PEG--based PROTAC linker can be used in the synthesis of PROTACs.
|
-
- HY-141003
-
|
PROTAC Linkers
|
Cancer
|
3,4-Dibromo-Mal-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138533
-
|
PROTAC Linkers
|
Cancer
|
Thiol-C10-amide-PEG8 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130742
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG8-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG8-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130192
-
|
PROTAC Linkers
|
Cancer
|
Cbz-NH-PEG8-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133301
-
|
PROTAC Linkers
|
Cancer
|
HO-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-133342
-
|
PROTAC Linkers
|
Cancer
|
H2N-PEG8-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-144078
-
|
PROTAC Linkers
|
Cancer
|
Bromo-PEG8-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130228
-
|
PROTAC Linkers
|
Cancer
|
N3-PEG8-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . N3-PEG8-CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-133469
-
|
PROTAC Linkers
|
Cancer
|
Methyltetrazine-PEG8-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG8-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138377
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG8-C-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-C-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-141007
-
|
PROTAC Linkers
|
Cancer
|
3,4-Dibromo-Mal-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-101159
-
|
ADC Linker
|
Cancer
|
Mal-amido-PEG8-C2-acid (example 142) is a nonclaevable ADC linker, extracted from patent US2018339985 .
|
-
- HY-163675
-
|
ADC Linker
|
Cancer
|
Maleimide-PEG8-Val-Ala-PAB is an ADC linker composed of the cleavable Val-Ala-PAB (HY-125933) linker and the probe molecule Maleimide (HY-W007324). Maleimide-PEG8-Val-Ala-PAB can be used to connect Cetuximab (HY-P9905) monoclonal antibody and CDK inhibitor SNS-032 (HY-10008) to synthesize antibody-drug conjugates (ADCs) .
|
-
- HY-135942
-
|
PROTAC Linkers
|
Cancer
|
Cbz-NH-PEG8-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138406
-
|
PROTAC Linkers
|
Cancer
|
Boc-NH-PEG8-C2-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-138532
-
|
PROTAC Linkers
|
Cancer
|
m-PEG8-amide-C10-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-145246
-
-
- HY-148425
-
|
ADC Linker
|
Cancer
|
Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-158348
-
-
- HY-140767
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG8-C1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-C1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-138391
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG8-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-141316
-
|
PROTAC Linkers
|
Cancer
|
m-PEG8-(CH2)12-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-49206
-
|
ADC Linker
|
Cancer
|
CbzNH-PEG8-amide-bis(pentayl-5OBz) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
|
-
- HY-140459
-
|
PROTAC Linkers
|
Cancer
|
2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-141146
-
|
ADC Linker
|
Cancer
|
Mal-amido-PEG8-val-gly-PAB-OH is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-141051
-
|
PROTAC Linkers
|
Cancer
|
N-(m-PEG9)-N'-(propargyl-PEG8)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(m-PEG9)-N'-(propargyl-PEG8)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140774
-
|
PROTAC Linkers
|
Cancer
|
Azido-PEG8-CH2COO-PFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-CH2COO-PFP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140470
-
|
PROTAC Linkers
|
Cancer
|
Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-130863
-
|
PROTAC Linkers
|
Cancer
|
Mal-NH-PEG8-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-139957
-
-
- HY-W040135
-
-
- HY-131157
-
|
ADC Linker
|
Cancer
|
Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a cleavable antibody agent conjugate linker used in the synthesis of antibody-drug conjugates (ADCs) . Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-147231
-
|
Others
|
Cancer
|
SG3400 delate (Mal-amido-PEG8) (compound 21) is an intermediate for the synthesis of ADC molecules. SG3400 delete is an effective toxin molecule with anticancer activity. SG3400 delete can be used in cancer research .
|
-
- HY-135933
-
|
PROTAC Linkers
|
Cancer
|
Boc-NH-PEG8-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-160247
-
|
Drug-Linker Conjugates for ADC
|
Others
|
Boc-Lys-PEG8-N-bis(D-glucose) (compound 89-5) is a drug linker that can be used in the synthesis of antibody-drug conjugates (ADCs) extracted from patent WO2023280227A2 .
|
-
- HY-145249
-
|
PROTAC Linkers
|
Inflammation/Immunology
|
ATP-PEG8-Biotin is a PEG-based linker that incorporates ATP. ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation .
|
-
- HY-131912
-
-
- HY-130375
-
|
PROTAC Linkers
|
Cancer
|
Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG8-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-145399
-
SG 3932
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
Mal-PEG8-amide-Val-Ala-(4-NH2)-Exatecan is a Drug-Linker Conjugates for ADC, which comprises a topoisomerase inhibitor and a linker for ligand unit connecting. Mal-PEG8-amide-Val-Ala-(4-NH2)-Exatecan can be used to synthesis antibody-drug conjugate (ADC) .
|
-
- HY-128945
-
|
ADC Linker
|
Inflammation/Immunology
Cancer
|
CL2A is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker .
|
-
- HY-128945A
-
|
ADC Linker
|
Inflammation/Immunology
Cancer
|
CL2A TFA is a claevable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A TFA is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker .
|
-
- HY-D2117
-
|
Fluorescent Dye
|
Others
|
TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-132288
-
|
E3 Ligase Ligand-Linker Conjugates
|
Cancer
|
Pom-8PEG, an E3 ligase ligand-linker conjugate, incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase and an 8-unit PEG linker. Pom-8PEG can be used in the synthesis of PROTAC, such as IDO1 PROTAC degrader .
|
-
- HY-161780
-
|
Drug-Linker Conjugates for ADC
CDK
|
Cancer
|
Maleimide-Val-Ala-PAB-SNS032 is a conjugate of ADC toxin and linker. SNS032 is an inhibitor for CDK, inhibiting the cell cycle at G1/S phase and cell viability of cancer cells. Maleimide-Val-Ala-PAB is a cleavable ADC linker. Maleimide-Val-Ala-PAB-SNS032 can be utilized for the synthesis of ADC molecules .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-D2107
-
|
Fluorescent Dyes/Probes
|
TAMRA-PEG8-NHS is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-NHS contains NHS groups that react with ammonia to form ester bonds.
|
-
- HY-D2110
-
|
Fluorescent Dyes/Probes
|
TAMRA-PEG8-COOH is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-D2141
-
|
Fluorescent Dyes/Probes
|
Cy3-PEG8-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 8 PEG units. Cy3-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D2159
-
|
Fluorescent Dyes/Probes
|
Cy5-PEG8-Tetrazin is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG8-Tetrazin contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D2114
-
|
Fluorescent Dyes/Probes
|
TAMRA-PEG8-Alkyne is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-156309
-
|
Fluorescent Dyes/Probes
|
Coumarin-PEG8-tetrazine is a dye derivative of Coumarin (HY-N0709) containing 8 PEG units. Coumarin-PEG8-tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D2116
-
|
Fluorescent Dyes/Probes
|
TAMRA-PEG8-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D2117
-
|
Fluorescent Dyes/Probes
|
TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
Cat. No. |
Product Name |
Type |
-
- HY-140956
-
|
Drug Delivery
|
DSPE-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
Cat. No. |
Product Name |
|
Classification |
-
- HY-153962
-
|
|
Azide
|
SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 is a Drug-Linker Conjugate for ADC. SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 consists of the anti-cancer agent SN38 (HY-13704) and a linker Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 (HY-131157). SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 can be used for synthesis of ADCs . SN38-PAB-Lys(MMT)-oxydiacetamide-PEG8-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-130376
-
|
|
PROTAC Synthesis
ADC Synthesis
Alkynes
|
Propargyl-PEG8-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130377
-
|
|
Alkynes
PROTAC Synthesis
ADC Synthesis
|
Propargyl-PEG8-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-bromide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130379
-
|
|
ADC Synthesis
PROTAC Synthesis
Alkynes
|
Propargyl-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria . Propargyl-PEG8-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-156379
-
-
- HY-140268
-
|
|
PROTAC Synthesis
DBCO
|
DBCO-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG8-acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-D2141
-
|
|
Labeling and Fluorescence Imaging
Alkynes
|
Cy3-PEG8-Alkyne is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 8 PEG units. Cy3-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D2159
-
|
|
Tetrazine
|
Cy5-PEG8-Tetrazin is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 7 PEG units. Cy5-PEG8-Tetrazin contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-D2114
-
|
|
Alkynes
Labeling and Fluorescence Imaging
|
TAMRA-PEG8-Alkyne is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Alkyne contains Alkyne groups and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141161B
-
|
|
TCO
|
(R)-TCO-PEG8-acid is an ADC linker containing 8 PEG units. (R)-TCO-PEG8-acid can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-141161
-
|
|
TCO
|
TCO-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141265
-
|
|
Tetrazine
|
Methyltetrazine-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-115414
-
|
|
PROTAC Synthesis
Alkynes
|
Bis-propargyl-PEG8 (compound 16e) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-130374
-
|
|
PROTAC Synthesis
Alkynes
|
Propargyl-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG8-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140273
-
|
|
PROTAC Synthesis
DBCO
|
DBCO-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG8-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140065
-
|
|
BCN
PROTAC Synthesis
|
endo-BCN-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG8-acid is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140316
-
|
|
DBCO
PROTAC Synthesis
|
m-PEG8-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG8-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-130910
-
|
|
PROTAC Synthesis
Alkynes
|
Propargyl-PEG8-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG8-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-156309
-
|
|
Labeling and Fluorescence Imaging
Tetrazine
|
Coumarin-PEG8-tetrazine is a dye derivative of Coumarin (HY-N0709) containing 8 PEG units. Coumarin-PEG8-tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-140454
-
|
|
ADC Synthesis
PROTAC Synthesis
Azide
|
Azido-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG8-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-156497
-
-
- HY-156477
-
|
|
Tetrazine
|
Me-Tet-PEG8-NHBoc is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-NHBoc can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-130182
-
|
|
ADC Synthesis
Alkynes
PROTAC Synthesis
|
Propargyl-PEG8-NH2 (compound 3b) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NH2 is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG8-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140070
-
|
|
BCN
PROTAC Synthesis
|
endo-BCN-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG8-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140883
-
|
|
PROTAC Synthesis
Alkynes
|
Boc-NH-PEG8-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Boc-NH-PEG8-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-135932
-
|
|
PROTAC Synthesis
Alkynes
|
m-PEG8-O-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . m-PEG8-O-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D2116
-
|
|
Labeling and Fluorescence Imaging
Tetrazine
|
TAMRA-PEG8-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-141169
-
|
|
TCO
|
TCO-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141181
-
|
|
TCO
|
TCO-PEG8-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141189
-
|
|
TCO
|
TCO-PEG8-TCO is a PEG-based PROTAC linker can be used in the synthesis of PROTACs .
|
-
- HY-141173
-
|
|
TCO
|
TCO-PEG8-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141270
-
|
|
Tetrazine
|
Methyltetrazine-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141273
-
|
|
Tetrazine
|
Methyltetrazine-PEG8-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-141169A
-
|
|
TCO
|
(S)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (S)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-130184
-
|
|
PROTAC Synthesis
ADC Synthesis
Azide
|
Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-156324
-
|
|
BCN
|
BCN-exo-PEG8-NHS is an ADC Linker containing 8 PEG units. BCN-exo-PEG8-NHS contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-156301A
-
|
|
Tetrazine
|
Me-Tet-PEG8-NH2 (hydrochloride) is an ADC Linker containing 2 PEG units. Me-Tet-PEG8-NH2 (hydrochloride) can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.
|
-
- HY-140635
-
|
|
Azide
PROTAC Synthesis
|
Ald-CH2-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Ald-CH2-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-131088
-
|
|
Azide
|
N3-PEG8-Phe-Lys-PABC-Gefitinib is a agent-linker conjugate for ADC with potent antitumor activity by using the anti-tumor agent, Gefitinib (orally active EGFR tyrosine kinase inhibitor), linked via the cleavable linker N3-PEG8-Phe-Lys-PABC. N3-PEG8-Phe-Lys-PABC-Gefitinib is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-156312
-
|
|
Tetrazine
|
Me-Tet-PEG8-Maleimide is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-130204
-
|
|
PROTAC Synthesis
Azide
|
m-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140773
-
|
|
Azide
PROTAC Synthesis
|
Azido-PEG8-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140799
-
|
|
PROTAC Synthesis
Azide
|
Azide-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azide-PEG8-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140216
-
|
|
Azide
PROTAC Synthesis
|
Azido-PEG8-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-amine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140860
-
|
|
Azide
PROTAC Synthesis
|
Trityl-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Trityl-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-140815
-
|
|
Azide
PROTAC Synthesis
|
Azido-PEG8-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-132010
-
|
|
PROTAC Synthesis
Azide
|
Benzyl-PEG8-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Benzyl-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-132055
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Azide
PROTAC Synthesis
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Azido-PEG8-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-THP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-138437
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Azide
PROTAC Synthesis
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Azido-PEG8-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-TFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-138706
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PROTAC Synthesis
Azide
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Azido-PEG8-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG8-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-138708
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PROTAC Synthesis
Azide
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Azido-PEG8-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG8-NHBoc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-130742
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Azide
PROTAC Synthesis
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Azido-PEG8-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs . Azido-PEG8-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-130228
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Azide
PROTAC Synthesis
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N3-PEG8-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . N3-PEG8-CH2COOH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-133469
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Tetrazine
Azide
PROTAC Synthesis
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Methyltetrazine-PEG8-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG8-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-138377
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Azide
PROTAC Synthesis
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Azido-PEG8-C-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-C-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-140767
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Azide
PROTAC Synthesis
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Azido-PEG8-C1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-C1-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-138391
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Azide
PROTAC Synthesis
Alkynes
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Azido-PEG8-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-140459
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PROTAC Synthesis
Azide
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2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-141051
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Alkynes
PROTAC Synthesis
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N-(m-PEG9)-N'-(propargyl-PEG8)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . N-(m-PEG9)-N'-(propargyl-PEG8)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140774
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Azide
PROTAC Synthesis
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Azido-PEG8-CH2COO-PFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG8-CH2COO-PFP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-131157
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ADC Synthesis
Azide
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Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a cleavable antibody agent conjugate linker used in the synthesis of antibody-drug conjugates (ADCs) . Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-130375
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PROTAC Synthesis
Alkynes
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Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs . Propargyl-PEG8-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D2117
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Tetrazine
Labeling and Fluorescence Imaging
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TAMRA-PEG4-Me-Tet is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG8-Me-Tet contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
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Cat. No. |
Product Name |
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Classification |
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- HY-101530A
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PEG 8 stearate
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Emulsifiers
Bases
Solubilizing Agents
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Polyoxyl 8 stearate can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-140956
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Pegylated Lipids
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DSPE-PEG8-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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- HY-140950
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Pegylated Lipids
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m-PEG8-DSPE is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
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