Please Note
•  This promotion starts from 10/01/2024 in North America only.
•  This promotion does not include inhibitor products.
•  20% off all selling Recombinant Proteins, Kits, Antibodies, Inhibitory Antibodies, Fluorescent Dye, siRNA, miRNA, Lipid Nanoparticles, and
Isotope-Labeled Compounds (including customization services) products in stock on MedChemExpress (MCE).
•  No participation if the product is purchased on the third party or other platform.
•  All rights of interpretation belong to MedChemExpress (MCE).
Recombinant Proteins
MedChemExpress (MCE) provides a comprehensive catalog of recombinant proteins include: cytokines and growth factors, viral proteins, immune checkpoint proteins, CAR-T related proteins, CD antigens, receptor proteins and enzymes.
Highlights of MCE’s Recombinant Proteins
• Superior Biological Activity
• High Purity
• Excellent Lot-to-Lot Consistency
• Specificity Guaranteed
Category Cat. No. Product Name
Enzymes &
Regulators 		HY-P7539 APT-1/LYPLA1, Human (His)
HY-P7442 ACE2, Human (HEK293, hFc, solution)
HY-P7419 Vaspin, Human
HY-P7381 Kallikrein-11, Human (Sf9)
Cytokines and
Growth Factors		 HY-P7383 LIX/CXCL5, Mouse (74a.a, CHO)
HY-P7318 AITRL/TNFSF18, Human
HY-P7362 Glia maturation factor beta/GMFB, Human
HY-P7317 4-1BB/TNFRSF9, Human (CHO, Fc)
HY-P7327 CD276/B7-H3, Human (HEK293, His)
Immune
Checkpoint
Proteins 		HY-P70060 BTN1A1, Human (HEK293, Fc)
HY-P72699 CD96, Mouse (HEK293, His)
HY-P700035AF Animal-Free CD70, Human (His)
Fc Receptors HY-P70708 Fc gamma RIII/CD16, Mouse (185a.a, HEK293, His)
HY-P72714 CD64, Mouse (273a.a, HEK293, His)
HY-P75644 Fc gamma RIIA/CD32a Protein, Human (H167R, HEK293, Fc)
HY-P75388 CD64, Rat (HEK293, His)
CD Antigens HY-P70768 CD79B, Human (Biotinylated, HEK293, His-Avi)
HY-P700436 FGFR-1 beta, Human (HEK293, hFc)
HY-P72350 Basigin/CD147, Human (Biotinylated, HEK293, Avi-His)
Fluorescent Dye
MCE offers 2,600+ high quality fluorescent dye probes, covering many popular
research fields, with high sensitivity, good stability and high fluorescence intensity to fully meet
your experimental needs and escort your experiments.
Category Cat. No. Product Name Color
PH probe HY-101883 BCECF-AM Blue
Cl- probe HY-D0936 SPQ Blue
Label Probe HY-D1792 Vari Fluor 555 SE Red
HY-D1886 Vari Fluor 647 SE /
HY-D1085 AMCA-X SE Blue
Substrate HY-W116594 X-GalNAc Blue
ROS Probe HY-D1158 HKOCl-4m Green
HY-D1156A HKSOX-1m (5/6-mixture) (hydrobromide) Green
Antibodies
MCE offers 4,000+ high-quality primary antibodies and secondary antibodies for autophagy,
apoptosis, immunity, cell cycle, and many other hot signaling pathways, covering a wide range of
popular targets to accelerate your scientific research!
Inhibitory Antibodies
MCE offers 1,700+ inhibitory antibodies manufactured under stringent quality
control processes. These include monoclonal antibodies, bispecific antibodies, fusion proteins,
rat/mouse in vivo antibodies, isotype control antibodies, etc.
Kits
MCE offers a wide range of high-quality, cost-effective,
ready-to-use kits in the areas of molecular biology, protein biology, and cell biology.
16,000+ siRNAs (HY-RS)
Pre-designed siRNA Set contains 3 siRNAs for target gene (human, mouse, or rat), a negative control,
a positive control, and a FAM-labeled negative control.
We guarantee that when the transfection efficiency exceeds 80%, at least one siRNA will silence the
target mRNA by at least 70%. If not, we will synthesize 3 new siRNAs for free.
Component Quantity Description
siRNA-1 5 nmoL Three different siRNAs are designed for different regions of the target gene.
siRNA-2
siRNA-3
siRNA Negative
Control		 5 nmoL There is no homology between negative control sequence and the target gene sequence.
FAM-labeled siRNA Negative Control 5 nmoL It is used to detect the transfection efficiency of siRNA using fluorescence microscopy or flow cytometry.
GAPDF siRNA Psositive Control 5 nmoL It is used to confirm that the RNAi experiments were performed correctly.
18,000+ miRNAs (HY-R/HY-RI)
MCE has developed miRNA mimics & inhibitors & agomirs & antagomirs for
studying miRNA function based on mature miRNA sequences in the miRBase database.
Category Characteristic Description
miRNA mimic Similar to endogenous miRNA duplex sequences, it can mimic endogenous miRNA. Transfection reagents are required, no need to construct vectors. Suitable for cellular experiments.
miRNA inhibitor Specifically binds to mature miRNA and inhibits miRNA function.
miRNA agomir Similar to endogenous miRNA duplex sequences, it can mimic endogenous miRNA. Using special chemical modification and end labeling techniques.
It can be administered to animals by injection or other methods.
miRNA antagomir Specifically binds to mature miRNA and inhibits miRNA function.
500+ Excipients for Lipid Nanoparticles
Lipid Nanoparticles (LNPs) are lipid-based drug delivery systems for delivering nucleic acids. There are four
essential components of LNP formulations: cationic lipids, PEGylated lipids, helper lipids, and cholesterol.
MCE offers 500+ lipids that will allow you to tailor your lipid based delivery systems.
Cat. No. Product Name Description
HY-112251 D-Lin-MC3-DMA Cationic Lipids
Neutralize negative charges, facilitate encapsulation, and cell uptake in LNPs.
HY-138170 ALC-0315
HY-134541 SM-102
HY-145405 C12-200
HY-145799 5A2-SC8
HY-134781 CKK-E12
HY-112772A 98N12-5
HY-112754A DOTAP chloride
HY-138300 ALC-0159 PEGylated Lipids
A class of PEG derivatives that is attached with lipid moiety, improve circulation times for LNP encapsulated drugs and reduce non-specific uptakes.
HY-112764 DMG-PEG 2000
HY-145411 PEG2000-C-DMG
HY-112760 DSPE-mPEG2000 sodium
HY-140739 DSPE-PEG2000-Maleimide
HY-W040193 DSPC Phospholipids
The commonly used helper lipids that can facilitate cell uptake and endosomal release.
HY-109506 DPPC
HY-112005 DOPE
HY-N0322 Cholesterol Cholesterol
Increase the stability of LNPs and decrease their fluidity.
HY-113217 Cholesteryl oleate
HY-137131 DC-Chol hydrochloride
HY-W440911 DSPE-PEG-Cy5, MW 2000 Fluorescent Lipids
A class of lipids molecules attached to a fluorophore.
HY-W440915 DSPE-PEG-FITC, MW 2000
HY-W440886 DSPE-PEG-Biotin, MW 3400
Isotope-Labeled Compounds
MCE offers 8,000+ high-quality isotope-labeled compounds, all of which are stable isotope compounds (such as 2H, 13C, 15N, 17O/18O, 34S, etc.). MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. They have applications in various life science research areas, such as metabolomics, proteomics, glycomics, clinical pharmacology, deuterated drug development, etc. It has a significant advantage in tracing and internal standard quantification.
Some Advantages of MCE's Isotope-Labeled Compounds
• Different kinds of isotopic atoms: 2H (D), 13C, 15N, 17O/18O, 34S, etc
• Quantitative test accuracy can reach PPM level
• Longer tracing time, not limited by half-life
• Custom synthesis service available
Customer Validation
D-glucose-13C6 (HY-B0389A) was used to trace fatty acid (FA) metabolism in HepG2 cells stably transfected with shFASRL and its control shNC and found that after the knockdown of FASRL, newly synthesized FAs labeled with 13C were significantly reduced.

Adv. Sci (Weinh). 2022 Oct 28;10(1):e2204711.

Category Cat. No. Drug Name Description
Tracers HY-B0389A D-Glucose-13C6 Tracers research, Metabolic Flux Analysis (MFA).
HY-N0390S1 L-Glutamine-13C5
Internal Standard
for TDM		 HY-14187S Amiodarone-d10 hydrochloride Internal Standard (LCMS, LC-MS/MS, GCMS, NMR).
HY-10585S1 Valproic acid-d6
HY-17514S Itraconazole-d5
Internal Standard
for Vitamins 		HY-76814 Calcitriol-d6
HY-A0020S Eldecalcitol-d6
Internal Standard
for Newborn Screening		 HY-I1124 L-Valine-d8
HY-N0215S12 L-Phenylalanine-d5
Internal Standard
for Food		 HY-136406S Bongkrekic acid-13C28
HY-152072S Deoxynivalenol-13C15
Internal Standard
for Pesticides		 HY-B0838S Imidacloprid-d4
HY-117386S Methoxyfenozide-d9
Internal Standard
for Veterinary Medicine		 HY-B0318S1 Metronidazole-d4
HY-B0802AS Terbutaline-d9