1. Gene
  2. CDKN1A - cyclin dependent kinase inhibitor 1A Gene

CDKN1A - cyclin dependent kinase inhibitor 1A Gene

Homo sapiens

Also known as P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1

Gene ID: 1026 | Gene type: protein coding

About CDKN1A

Cytogenetic location: 6p21.2 Genomic coordinates (GRCh38): 6:36,676,463-36,687,332 (from NCBI)

This gene has 8 transcripts (splice variants), 196 orthologues, 2 paralogues and is associated with 77 phenotypes. Ubiquitous expression in colon (RPKM 71.4), gall bladder (RPKM 68.8) and 24 other tissues.

Summary

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen, a DNA Polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of cyclin-dependent kinase2, and may be instrumental in the execution of Apoptosis following Caspase activation. Mice that lack this gene have the ability to regenerate damaged or missing tissue. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Sep 2015]

CDKN1A Products(10)

mRNA Protein Name
NM_000389.5 NP_000380.1 cyclin-dependent kinase inhibitor 1 isoform 1
NM_001220777.2 NP_001207706.1 cyclin-dependent kinase inhibitor 1 isoform 1
NM_001220778.2 NP_001207707.1 cyclin-dependent kinase inhibitor 1 isoform 1
NM_001291549.3 NP_001278478.1 cyclin-dependent kinase inhibitor 1 isoform 2
NM_001374509.1 NP_001361438.1 cyclin-dependent kinase inhibitor 1 isoform 2
NM_001374510.1 NP_001361439.1 cyclin-dependent kinase inhibitor 1 isoform 3
NM_001374511.1 NP_001361440.1 cyclin-dependent kinase inhibitor 1 isoform 4
NM_001374512.1 NP_001361441.1 cyclin-dependent kinase inhibitor 1 isoform 5
NM_001374513.1 NP_001361442.1 cyclin-dependent kinase inhibitor 1 isoform 1
NM_078467.3 NP_510867.1 cyclin-dependent kinase inhibitor 1 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables cyclin-dependent protein kinase activating kinase activity IDA
IDA: Inferred from direct assay
9106657 GOA
enables cyclin-dependent protein serine/threonine kinase inhibitor activity IDA
IDA: Inferred from direct assay
11463845 GOA
enables molecular function activator activity IMP
IMP: Inferred from mutant phenotype
17553787 GOA
enables molecular function inhibitor activity IDA
IDA: Inferred from direct assay
8876165 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
8756624 GOA
enables protein kinase binding IPI
IPI: Inferred from physical interaction
8876165 GOA
enables protein kinase inhibitor activity IMP
IMP: Inferred from mutant phenotype
8876165 GOA
enables protein sequestering activity EXP
EXP: Inferred from Experiment
11595739 GOA
enables protein sequestering activity IMP
IMP: Inferred from mutant phenotype
11595739 GOA
enables protein serine/threonine kinase binding IPI
IPI: Inferred from physical interaction
11463845 GOA
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
8876165 GOA
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
23026136 GOA
Biological Process GO Annotation Evidence Reference Source
involved in DNA damage response IMP
IMP: Inferred from mutant phenotype
20160708 GOA
involved in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest IDA
IDA: Inferred from direct assay
15149599 GOA
involved in Ras protein signal transduction IEP
IEP: Inferred from expression pattern
9054499 GOA
involved in cellular response to amino acid starvation IMP
IMP: Inferred from mutant phenotype
26102367 GOA
involved in cellular response to cell-matrix adhesion IMP
IMP: Inferred from mutant phenotype
17553787 GOA
involved in cellular response to ionizing radiation IMP
IMP: Inferred from mutant phenotype
20160708 GOA
acts upstream of cellular senescence IMP
IMP: Inferred from mutant phenotype
17553787 GOA
involved in cellular senescence IMP
IMP: Inferred from mutant phenotype
15149599 GOA
involved in import into nucleus IMP
IMP: Inferred from mutant phenotype
12417334 GOA
involved in mitotic G2 DNA damage checkpoint signaling IMP
IMP: Inferred from mutant phenotype
23213251 GOA
involved in negative regulation of DNA biosynthetic process IMP
IMP: Inferred from mutant phenotype
11595739 GOA
acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle IGI
IGI: Inferred from genetic interaction
21628527 GOA
involved in negative regulation of cell growth IDA
IDA: Inferred from direct assay
10208428 GOA
involved in negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
10208428 GOA
involved in negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
17553787 GOA
involved in negative regulation of cyclin-dependent protein kinase activity IMP
IMP: Inferred from mutant phenotype
8876165 GOA
involved in negative regulation of phosphorylation IDA
IDA: Inferred from direct assay
10208428 GOA
involved in negative regulation of protein binding IMP
IMP: Inferred from mutant phenotype
11595739 GOA
involved in negative regulation of vascular associated smooth muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
25681685 GOA
involved in positive regulation of fibroblast proliferation IMP
IMP: Inferred from mutant phenotype
17420273 GOA
acts upstream of or within positive regulation of protein kinase activity IDA
IDA: Inferred from direct assay
22869755 GOA
involved in positive regulation of reactive oxygen species metabolic process IMP
IMP: Inferred from mutant phenotype
20160708 GOA
involved in regulation of G1/S transition of mitotic cell cycle IDA
IDA: Inferred from direct assay
10208428 GOA
involved in regulation of G2/M transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
17553787 GOA
involved in regulation of cell cycle IDA
IDA: Inferred from direct assay
15149599 GOA
involved in regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
26102367 GOA
involved in regulation of cell cycle G1/S phase transition IMP
IMP: Inferred from mutant phenotype
23213251 GOA
Cellular Component GO Annotation Evidence Reference Source
part of PCNA-p21 complex IDA
IDA: Inferred from direct assay
18794347 GOA
part of PCNA-p21 complex IMP
IMP: Inferred from mutant phenotype
11595739 GOA
part of PCNA-p21 complex IPI
IPI: Inferred from physical interaction
11463845 GOA
part of cyclin-dependent protein kinase holoenzyme complex IDA
IDA: Inferred from direct assay
17420273 GOA
located in nucleolus IDA
IDA: Inferred from direct assay
22869755 GOA
located in nucleoplasm IDA
IDA: Inferred from direct assay
22869755 GOA
located in nucleus IDA
IDA: Inferred from direct assay
11343236 GOA
part of protein-containing complex IDA
IDA: Inferred from direct assay
22869755 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CDKN1A Protein Structure

CDI

CDI: Cyclin-dependent kinase inhibitor (19 - 69)

  • 0
  • 100
  • 164 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase inhibitor 1

CDK-interacting protein 1

CDKN1A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
CDKN1A P38936 FKBP1A Homo sapiens Q0VDC6
Validated Y2H
32814053
Intra
CDKN1A P38936 FKBP1A Homo sapiens Q0VDC6
Y2H Pooling
32814053
Intra
CDKN1A P38936 FKBP1A Homo sapiens Q0VDC6
Y2H Array
32814053
Intra
CDKN1A P38936 CDK5 Homo sapiens Q00535
Anti Tag CoIP
33961781
Intra
CDKN1A P38936 CDK5 Homo sapiens Q00535
Pull Down
30833792
Intra
CDKN1A P38936 CDK5 Homo sapiens Q00535
SPR
15890360
Intra
CDKN1A P38936 CDK14 Homo sapiens O94921
Anti Tag CoIP
33961781
Intra
CDKN1A P38936 CDK14 Homo sapiens O94921
Anti Tag CoIP
17517622
Intra
CDKN1A P38936 CDK14 Homo sapiens O94921
Y2H
17517622
Intra
CDKN1A P38936 SARS1 Homo sapiens P49591
Y2H Pooling
32814053
Intra
CDKN1A P38936 SARS1 Homo sapiens P49591
Validated Y2H
32814053
Intra
CDKN1A P38936 SARS1 Homo sapiens P49591
Y2H Array
32814053
Intra
CDKN1A P38936 EIF2S3 Homo sapiens P41091
Validated Y2H
32814053
Intra
CDKN1A P38936 EIF2S3 Homo sapiens P41091
Y2H Array
32814053
Intra
CDKN1A P38936 EIF2S3 Homo sapiens P41091
Y2H Pooling
32814053
Intra
CDKN1A P38936 SIPA1 Homo sapiens Q96FS4
Y2H
21988832
Intra
CDKN1A P38936 REL Homo sapiens Q04864-2
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 REL Homo sapiens Q04864-2
Validated Y2H
32296183
Intra
CDKN1A P38936 REL Homo sapiens Q04864-2
Y2H Array
32296183
Intra
CDKN1A P38936 HOOK2 Homo sapiens Q96ED9-2
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 HOOK2 Homo sapiens Q96ED9-2
Validated Y2H
32296183
Intra
CDKN1A P38936 HOOK2 Homo sapiens Q96ED9-2
Y2H Array
32296183
Intra
CDKN1A P38936 DMWD Homo sapiens G5E9A7
Y2H Array
32814053
Intra
CDKN1A P38936 DMWD Homo sapiens G5E9A7
Validated Y2H
32814053
Intra
CDKN1A P38936 DMWD Homo sapiens G5E9A7
Y2H Pooling
32814053
Intra
CDKN1A P38936 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra
CDKN1A P38936 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra
CDKN1A P38936 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra
CDKN1A P38936 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 MTUS2 Homo sapiens Q5JR59-3
Validated Y2H
32296183
Intra
CDKN1A P38936 STAT5B Homo sapiens P51692
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 STAT5B Homo sapiens P51692
Y2H Array
32296183
Intra
CDKN1A P38936 STAT5B Homo sapiens P51692
Validated Y2H
32296183
Intra
CDKN1A P38936 SHISA6 Homo sapiens Q6ZSJ9
Y2H Array
32296183
Intra
CDKN1A P38936 SHISA6 Homo sapiens Q6ZSJ9
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 SHISA6 Homo sapiens Q6ZSJ9
Validated Y2H
32296183
Intra
CDKN1A P38936 CDK3 Homo sapiens Q00526
LexA B52 Complement
24218572
Intra
CDKN1A P38936 CDK3 Homo sapiens Q00526
Validated Y2H
32296183
Intra
CDKN1A P38936 KIFC3 Homo sapiens Q9BVG8-5
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 KIFC3 Homo sapiens Q9BVG8-5
Validated Y2H
32296183
Intra
CDKN1A P38936 KIFC3 Homo sapiens Q9BVG8-5
Y2H Array
32296183
Intra
CDKN1A P38936 SCML2 Homo sapiens Q9UQR0-1
Pull Down
24358021
Intra
CDKN1A P38936 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
Intra
CDKN1A P38936 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
CDKN1A P38936 LRP2BP Homo sapiens Q9P2M1
Y2H Array
32296183
Intra
CDKN1A P38936 LRP2BP Homo sapiens Q9P2M1
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 LRP2BP Homo sapiens Q9P2M1
Validated Y2H
32296183
Intra
CDKN1A P38936 NABP2 Homo sapiens Q9BQ15
Anti Tag CoIP
21242961
Intra
CDKN1A P38936 NABP2 Homo sapiens Q9BQ15
Confocal
21242961
Intra
CDKN1A P38936 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
32296183
Intra
CDKN1A P38936 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra
CDKN1A P38936 ERN1 Homo sapiens O75460-2
Validated Y2H
32814053
Intra
CDKN1A P38936 ERN1 Homo sapiens O75460-2
Y2H Array
32814053
Intra
CDKN1A P38936 ERN1 Homo sapiens O75460-2
Y2H Pooling
32814053
Intra
CDKN1A P38936 q9y649_human Homo sapiens Q9Y649
Y2H Array
32814053
Intra
CDKN1A P38936 q9y649_human Homo sapiens Q9Y649
Y2H Pooling
32814053
Intra
CDKN1A P38936 q9y649_human Homo sapiens Q9Y649
Validated Y2H
32814053
Intra
CDKN1A P38936 PRKAR1B Homo sapiens P31321
Validated Y2H
32296183
Intra
CDKN1A P38936 PRKAR1B Homo sapiens P31321
Y2H Array
32296183
Intra
CDKN1A P38936 PRKAR1B Homo sapiens P31321
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 CDK4 Homo sapiens P11802
Anti Tag CoIP
33961781
Intra
CDKN1A P38936 CDK4 Homo sapiens P11802
Pull Down
30833792
Intra
CDKN1A P38936 CDK4 Homo sapiens P11802
Protein Array
15232106
Intra
CDKN1A P38936 CDK4 Homo sapiens P11802
Anti Bait CoIP
9106657
Intra
CDKN1A P38936 CDK4 Homo sapiens P11802
Pull Down
8756624
Intra
CDKN1A P38936 CDK6 Homo sapiens Q00534
Protein Array
15232106
Intra
CDKN1A P38936 SKP1 Homo sapiens P63208
Anti Bait CoIP
16376880
Intra
CDKN1A P38936 SKP1 Homo sapiens P63208
PLA
25241761
Intra
CDKN1A P38936 FGFR3 Homo sapiens P22607
Validated Y2H
32814053
Intra
CDKN1A P38936 FGFR3 Homo sapiens P22607
Y2H Array
32814053
Intra
CDKN1A P38936 FGFR3 Homo sapiens P22607
Y2H Pooling
32814053
Intra
CDKN1A P38936 GSN Homo sapiens P06396
Validated Y2H
32814053
Intra
CDKN1A P38936 GSN Homo sapiens P06396
Y2H Pooling
32814053
Intra
CDKN1A P38936 GSN Homo sapiens P06396
Y2H Array
32814053
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Y2H Array
25416956
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Anti Tag CoIP
33961781
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
SLC
27107012
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Y2H Array
32296183
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Pull Down
30833792
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
MAPPIT
25416956
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Y2H Prey Pooling
25416956
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
BiFC
25416956
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
X-Ray Diffraction
8861913
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Validated Y2H
27107012
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Anti Bait CoIP
20605778
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Y2H Array
31515488
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
BFG-2H
27107012
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Pull Down
10873631
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Anti Tag CoIP
26496610
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Y2H Pooling
16189514
Intra
CDKN1A P38936 PCNA Homo sapiens P12004
Y2H
27107012
Intra
CDKN1A P38936 TRAF1 Homo sapiens Q13077
Y2H Array
25416956
Intra
CDKN1A P38936 TRAF1 Homo sapiens Q13077
Y2H Prey Pooling
25416956
Intra
CDKN1A P38936 TP53 Homo sapiens P04637
PLA
25241761
Intra
CDKN1A P38936 TP53 Homo sapiens P04637
Y2H
21900206
Intra
CDKN1A P38936 MKRN1 Homo sapiens Q9UHC7
Anti Tag CoIP
19536131
Intra
CDKN1A P38936 MKRN1 Homo sapiens Q9UHC7
Anti Bait CoIP
19536131
Intra
CDKN1A P38936 CDC6 Homo sapiens Q99741
Protein Array
15232106
Intra
CDKN1A P38936 CDC6 Homo sapiens Q99741
PLA
25241761
Intra
CDKN1A P38936 CDC45 Homo sapiens O75419
Protein Array
15232106
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385
Pull Down
30833792
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385
Y2H Prey Pooling
25416956
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385
Protein Array
15232106
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385
Validated Y2H
27107012
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385
BFG-2H
27107012
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385
Validated Y2H
25416956
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385
Pull Down
8756624
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385
Y2H Array
25416956
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385
Anti Tag CoIP
33961781
Intra
CDKN1A P38936 CCND1 Homo sapiens P24385
Y2H
21988832
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281
Pull Down
30833792
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281
Y2H Prey Pooling
25416956
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281
Y2H Array
21988832
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281
Protein Array
15232106
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281
PLA
25241761
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281
Validated Y2H
27107012
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281
Y2H Array
31515488
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281
BFG-2H
27107012
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281
Validated Y2H
25416956
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281
Anti Tag CoIP
26496610
Intra
CDKN1A P38936 CCND3 Homo sapiens P30281
Y2H Array
25416956
Intra
CDKN1A P38936 CCNB2 Homo sapiens O95067
Anti Tag CoIP
33961781
Intra
CDKN1A P38936 CCNB2 Homo sapiens O95067
Protein Array
15232106
Intra
CDKN1A P38936 CCNE2 Homo sapiens O96020
Pull Down
30833792
Intra
CDKN1A P38936 CCNE2 Homo sapiens O96020
Anti Tag CoIP
33961781
Intra
CDKN1A P38936 CCNE2 Homo sapiens O96020
Y2H
9840943
Intra
CDKN1A P38936 CCNE2 Homo sapiens O96020
Protein Array
15232106
Intra
CDKN1A P38936 CCNE2 Homo sapiens O96020
Anti Bait CoIP
24358021
Intra
CDKN1A P38936 CCNA1 Homo sapiens P78396
BRET
29997244
Intra
CDKN1A P38936 CCNA1 Homo sapiens P78396
Lumier
32814053
Intra
CDKN1A P38936 CCNA1 Homo sapiens P78396
Lumier
29997244
Intra
CDKN1A P38936 CCNA1 Homo sapiens P78396
Protein Array
15232106
Intra
CDKN1A P38936 CCNA1 Homo sapiens P78396
Pull Down
8756624
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941
Anti Bait CoIP
16765349
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941
Protein Array
15232106
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941
Anti Bait CoIP
17418410
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941
LexA B52 Complement
24218572
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941
Anti Bait CoIP
24358021
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941
SPR
15890360
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941
Pull Down
24358021
Intra
CDKN1A P38936 CDK2 Homo sapiens P24941
PLA
25241761
Intra
CDKN1A P38936 CDK1 Homo sapiens P06493
LexA B52 Complement
24218572
Intra
CDKN1A P38936 CDK1 Homo sapiens P06493
Anti Tag CoIP
26496610
Intra
CDKN1A P38936 CDK1 Homo sapiens P06493
Anti Tag CoIP
33961781
Intra
CDKN1A P38936 CDK1 Homo sapiens P06493
Pull Down
30833792
Intra
CDKN1A P38936 SKP2 Homo sapiens Q13309
Anti Tag CoIP
33961781
Intra
CDKN1A P38936 SKP2 Homo sapiens Q13309
Anti Bait CoIP
16376880
Intra
CDKN1A P38936 SKP2 Homo sapiens Q13309
Pull Down
30833792
Intra
CDKN1A P38936 CCNA2 Homo sapiens P20248
Pull Down
30833792
Intra
CDKN1A P38936 CCNA2 Homo sapiens P20248
Anti Tag CoIP
26496610
Intra
CDKN1A P38936 CCNA2 Homo sapiens P20248
Anti Tag CoIP
33961781
Intra
CDKN1A P38936 CCNA2 Homo sapiens P20248
SPR
15890360
Intra
CDKN1A P38936 CCNE1 Homo sapiens P24864
Anti Bait CoIP
16765349
Intra
CDKN1A P38936 CCNE1 Homo sapiens P24864
Y2H
21988832
Intra
CDKN1A P38936 CCNE1 Homo sapiens P24864
Anti Tag CoIP
33961781
Intra
CDKN1A P38936 CCNE1 Homo sapiens P24864
Pull Down
8756624
Intra
CDKN1A P38936 SPRED1 Homo sapiens Q7Z699
Y2H
21900206
Intra
CDKN1A P38936 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra
CDKN1A P38936 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra
CDKN1A P38936 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra
CDKN1A P38936 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
CDKN1A P38936 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 GOLGA2 Homo sapiens Q08379
Validated Y2H
32296183
Intra
CDKN1A P38936 INCA1 Homo sapiens Q0VD86
Y2H Array
32296183
Intra
CDKN1A P38936 INCA1 Homo sapiens Q0VD86
Validated Y2H
32296183
Intra
CDKN1A P38936 INCA1 Homo sapiens Q0VD86
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 USHBP1 Homo sapiens Q8N6Y0
Validated Y2H
32296183
Intra
CDKN1A P38936 USHBP1 Homo sapiens Q8N6Y0
Y2H Array
32296183
Intra
CDKN1A P38936 USHBP1 Homo sapiens Q8N6Y0
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 LZTS2 Homo sapiens Q9BRK4
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 LZTS2 Homo sapiens Q9BRK4
Validated Y2H
32296183
Intra
CDKN1A P38936 LZTS2 Homo sapiens Q9BRK4
Y2H Array
32296183
Intra
CDKN1A P38936 TEX11 Homo sapiens Q8IYF3
Y2H Pooling
16189514
Intra
CDKN1A P38936 TEX11 Homo sapiens Q8IYF3
Y2H Prey Pooling
25416956
Intra
CDKN1A P38936 TEX11 Homo sapiens Q8IYF3
Y2H Array
25416956
Intra
CDKN1A P38936 FNDC11 Homo sapiens Q9BVV2
Validated Y2H
32296183
Intra
CDKN1A P38936 FNDC11 Homo sapiens Q9BVV2
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 FNDC11 Homo sapiens Q9BVV2
Y2H Array
32296183
Intra
CDKN1A P38936 IKZF3 Homo sapiens Q9UKT9
Y2H Prey Pooling
25416956
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279
Anti Bait CoIP
16765349
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279
Validated Y2H
27107012
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279
BFG-2H
27107012
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279
Anti Tag CoIP
33961781
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279
Y2H Array
25416956
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279
Y2H Array
32296183
Intra
CDKN1A P38936 CCND2 Homo sapiens P30279
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 PCNA Homo sapiens Q6FI35
Anti Bait CoIP
16616141
Intra
CDKN1A P38936 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
CDKN1A P38936 KRT31 Homo sapiens Q15323
Y2H Array
25416956
Intra
CDKN1A P38936 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 KRT31 Homo sapiens Q15323
Validated Y2H
32296183
Intra
CDKN1A P38936 KRT31 Homo sapiens Q15323
Validated Y2H
25416956
Intra
CDKN1A P38936 KRTAP3-1 Homo sapiens Q9BYR8
Validated Y2H
32296183
Intra
CDKN1A P38936 KRTAP3-1 Homo sapiens Q9BYR8
Y2H Prey Pooling
32296183
Intra
CDKN1A P38936 KRTAP3-1 Homo sapiens Q9BYR8
Y2H Array
32296183
Cross
CDKN1A P38936 P27958-PRO_0000037566 Hepatitis C virus P27958-PRO_0000037566
Pull Down
10873631
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CDKN1A Proteins

Cat. No. Product Name Accession Purity
HY-P700570 CDKN1A Protein, Human (GST) P38936 (S2-P164) ≥95%

Related Diseases

Diseases Alias
Multiple Endocrine Neoplasia, Type I

Multiple Endocrine Neoplasia Type 1

MEN1

Wermer Syndrome

Multiple Endocrine Neoplasia 1

Multiple Endocrine Neoplasia, Type 1

Men I

Endocrine Adenomatosis, Multiple

Mea I

Men Type I

Wermer'S Syndrome

Men1 Syndrome

Multiple Endocrine Adenomatosis

Endocrine Adenomatosis Multiple

Men 1

Familial Multiple Endocrine Neoplasia Type I

Neoplasia, Endocrine, Multiple, Type 1

Multiple Endocrine Neoplasia

Tongue Carcinoma

Tongue Cancer

Malignant Neoplasm Of Tongue

Tongue Neoplasms

Tongue Neoplasm

Hypervitaminosis A

Hypervitaminosis A, Susceptibility To

Hyperalimentation Of Vitamin A

Papilloma

Papillomatosis

Li-Fraumeni Syndrome

Sarcoma Family Syndrome Of Li And Fraumeni

Sbla Syndrome

LFS

Li-Fraumeni Familiar Cancer Susceptibility Syndrome

Sarcoma, Breast, Leukaemia And Adrenal Gland Syndrome

Lfs1

Li Fraumeni Syndrome

Sarcoma, Breast, Leukemia, And Adrenal Gland Syndrome

Lfl

Sbla Syndrome Li-Fraumeni-Like Syndrome

Li-Fraumeni Syndrome 1

Thoracic Cancer

Thoracic Tumor

Thorax Cancer

Thorax Neoplasm

Tumor Of Thorax

Thoracic Neoplasms

Human Papillomavirus Infectious Disease

Hpv

Papillomavirus Infections

Human Papilloma Virus Infection

Cervical Adenocarcinoma

Adenocarcinoma Cervix Uteri

Adenocarcinoma Of Cervix

Adenocarcinoma Of The Uterine Cervix

Adenocarcinoma Of The Cervix Uteri

Retinoblastoma

RB

Trilateral Retinoblastoma

RB1

Retinoblastoma, Trilateral

Neuroblastoma Of Retina

Rb - Retinoblastoma

Eye Cancer, Retinoblastoma

Retinal Cancer

Retinal Tumor

Glioma, Retinal

Non-Hereditary Retinoblastoma

Childhood Cancer Retinoblastoma

Malignant Neoplasm Of Retina

Retinal Neoplasms

Adenocarcinoma

Adenocarcinomas

Adenoacanthoma Of Unspecified Site

Adenocarcinoid Of Unspecified Site

Adenocarcinoid Tumour Of Unspecified Site

Adenocarcinoma And Carcinoid Combined Of Unspecified Site

Adenocarcinoma Nos

Keratoacanthoma

Ka - [Keratoacanthoma]

Well-Differentiated Squamous Cell Carcinoma

Bladder Cancer

Urinary Bladder Cancer

Bladder Carcinoma

Urinary Bladder Carcinoma

Bladder Neoplasm

Bladder Tumor

Cancer, Bladder

Malignant Neoplasm Of Urinary Bladder

Carcinoma Of Bladder

Bladder Cancer, Somatic

Tumor Of The Bladder

Carcinoma Of Urinary Bladder

Bladder Carcinoma Urinary

Cancer Of The Urinary Bladder

Cancer, Urinary Bladder

Malignant Bladder Neoplasm

Malignant Bladder Tumor

Neoplasm Of The Bladder

Neoplasm Of The Urinary Bladder

Tumor Of The Urinary Bladder

Urinary Bladder Neoplasm

BLC

Urothelial Carcinoma Of The Bladder

Bladder Tumors

Urinary Bladder Neoplasms

Bladder Cancer Nos

Vesical Cancer Nos

Malignant Neoplasm Of Bladder, Part Unspecified

Malignant Tumour Of Urinary Bladder

Primary Malignant Neoplasm Of Bladder

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Squamous Cell Carcinoma

Epidermoid Carcinoma

Squamous Cell Cancer

Carcinoma, Squamous Cell

Squamous Cell Skin Cancer

Malignant Squamous Cell Tumor

Squamous Carcinoma

Squamous Cell Epithelioma

Carcinoma Squamous Cell

Neoplasms, Squamous Cell

Squamous Cell Carcinoma - Category

Malignant Squamous Cell Neoplasm

Squamous Cell Carcinoma Of Skin

Ataxia-Telangiectasia

Ataxia Telangiectasia

Louis-Bar Syndrome

AT

At1

Ataxia-Telangiectasia Syndrome

Ataxia - Telangiectasia Variant

Boder-Sedgwick Syndrome

Louis Bar Syndrome

Cerebello-Oculocutaneous Telangiectasia

Immunodeficiency With Ataxia Telangiectasia

A-T

Ataxia Telangiectasia Syndrome

Atm

Telangiectasia, Cerebello-Oculocutaneous

Ataxia-Telangiectasia Variant

Endometrial Cancer

Endometrial Carcinoma

Endometrial Neoplasm

Malignant Neoplasm Of Endometrium

Endometrioid Carcinoma

Endometrial Neoplasms

Carcinoma, Endometrioid

Endometrial Cancer, Familial

Endometrial Carcinoma, Somatic

Endometrial Cancer, Susceptibility To

Endometrial Ca

Malignant Endometrial Neoplasm

Neoplasm Of Endometrium

Primary Malignant Neoplasm Of Endometrium

Tumor Of Endometrium

Carcinoma Of The Endometrium

Endometrioid Carcinoma Of Female Reproductive System

ENDMC

Carcinoma Endometrioid

Endometrial Cancers

Cancer, Endometrial

Uterine Corpus Cancer

Polyploidy

Polyploid

Polyploidy Syndrome

Malignant Pleural Mesothelioma

Malignant Mesothelioma Of Pleura

Pleural Malignant Mesothelioma

Pancreatic Adenocarcinoma

Adenocarcinoma Of The Pancreas

Adenocarcinoma Of Pancreas

Pancreas Adenocarcinoma

Malignant Exocrine Neoplasm

Primary Pancreatic Adenocarcinoma

Adenocarcinoma Of Islet Cell Of Pancreas

Islet Cell Adenocarcinoma Of Unspecified Site

Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Transitional Cell Carcinoma

Transitional Cell Neoplasm

Carcinoma, Transitional Cell

Transitional Carcinoma

Transitional Cell Tumor

Urothelial Cell Carcinoma

Carcinoma Transitional Cell

Transitional Cell Carcinoma Of Bladder

Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Cancer Of The Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary

Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Bladder Urothelial Carcinoma

Bladder Transitional Cell Carcinoma

Transitional Cell Carcinoma Of Bladder

Transitional Cell Carcinoma Of The Bladder

Urinary Bladder Urothelial Carcinoma

Urothelial Bladder Carcinoma

Carcinoma Transitional Cell Bladder

Tcc - [Transitional Cell Carcinoma] Of Bladder

Breast Ductal Carcinoma

Ductal Breast Carcinoma

Duct Carcinoma

Carcinoma, Ductal

Mammary Ductal Carcinoma

Ductal Carcinoma

Glioblastoma

Glioblastoma Multiforme

Gbm

Adult Glioblastoma Multiforme

Grade Iv Adult Astrocytic Tumor

Primary Glioblastoma Multiforme

Spongioblastoma Multiforme

Adult Glioblastoma

Primary Glioblastoma

Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas

Colon Adenocarcinoma

Adenocarcinoma Of Colon

Adenocarcinoma Of The Colon

Colonic Adenocarcinoma

Pancreatic Cancer

Pancreatic Carcinoma

Carcinoma Of Pancreas

Familial Pancreatic Carcinoma

Pancreatic Neoplasm

Pancreatic Carcinoma, Familial

Malignant Neoplasm Of Pancreas

Pancreatic Acinar Carcinoma

Pancreatic Tumor

Familial Pancreatic Cancer

Neoplasm Of The Pancreas

Cancer Of The Pancreas

Pancreatic Carcinoma, Somatic

Pancreatic Cancer, Somatic

Ca Body Of Pancreas

Ca Head Of Pancreas

Ca Tail Of Pancreas

Malignant Neoplasm Of Body Of Pancreas

Malignant Neoplasm Of Head Of Pancreas

Malignant Neoplasm Of Tail Of Pancreas

Pancreas Neoplasm

Exocrine Cancer

Exocrine Pancreas Carcinoma

Hereditary Pancreatic Cancer

Hereditary Pancreatic Carcinoma

PNCA

Pancreatic Cancer, Susceptibility To

Carcinoma Of Head Of Pancreas

Pancreatic Neoplasms

Pancreatic Tumors

Cancer, Pancreatic

Cancer Of Pancreas

Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Focal Segmental Glomerulosclerosis

Familial Idiopathic Steroid-Resistant Nephrotic Syndrome

Focal Glomerulosclerosis

Fsgs

Segmental Glomerulosclerosis

Glomerulosclerosis, Focal Segmental

Fgs

Focal Glomerular Sclerosis

Familial Idiopathic Nephrotic Syndrome

Focal Sclerosis With Hyalinosis

Glomerulosclerosis, Focal

Glomerulosclerosis Focal

Glomerulosclerosis, Segmental, Focal

Focal Segmental Glomerulosclerosis, Not Otherwise Specified

Fibrosarcoma

Neoplasms, Fibrous Tissue

Fibrocytic Tumor

Fibrosarcoma Of Soft Tissue

Fibrous Tissue Neoplasm

Cystadenocarcinoma
Coronary Restenosis
Thyroid Gland Anaplastic Carcinoma

Anaplastic Thyroid Carcinoma

Anaplastic Thyroid Cancer

Thyroid Cancer, Anaplastic

Thyroid Carcinoma, Anaplastic

Thyroid Carcinoma Anaplastic

Laryngeal Squamous Cell Carcinoma

Epidermoid Carcinoma Of The Larynx

Squamous Cell Carcinoma Of Larynx

Squamous Cell Carcinoma Of The Larynx

Squamous Cell Carcinoma Of Head And Neck

Acute Promyelocytic Leukemia

Leukemia, Acute Promyelocytic

Acute Myeloblastic Leukemia Type 3

Aml M3

APL

Leukemia, Acute Promyelocytic, Somatic

Aml With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Apml

Acute Myeloblastic Leukemia 3

Acute Myeloid Leukemia With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Acute Myeloblastic Leukaemia Type 3

Acute Myeloid Leukaemia M3

Acute Myeloid Leukemia M3

Acute Promyelocytic Leukaemia

M3 Anll

Myeloid Leukemia, Acute, M3

Leukemia Promyelocytic Acute

Leukemia, Promyelocytic, Acute

Leukemia, Acute, Promyelocytic

Rectum Cancer

Malignant Neoplasm Of Rectum

Rectal Cancer

Cancer Of Rectum

Carcinoma Of Rectum

Carcinoma Of The Rectum

Malignant Rectal Tumor

Malignant Rectum Tumor

Malignant Tumor Of Rectum

Rectal Carcinoma

Rectal Cancers

Cancer, Rectal

Ureteral Obstruction
Lymphoblastic Lymphoma

Lymphoma, Lymphoblastic

Lymphoma Lymphoblastic

Precursor Cell Lymphoblastic Lymphoma

Precursor Cell Lymphoblastic Leukemia Lymphoma

Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

Cervical Cancer

Cervical Cancer, Somatic

Neoplasm Of Uterine Cervix

Cervix Cancer

Uterine Cervical Neoplasm

Cervical Neoplasm

Cervix Uteri Cancer

Tumor Of The Cervix Uteri

CERCA

Uterine Cervical Cancer

Neoplasms Cervical

Uterine Cervical Neoplasms

Cervical Cancers

Cancer, Cervical, Somatic

Malignant Tumor Of Cervix

Cervix Carcinoma

Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour

Kaposi Sarcoma

Kaposi'S Sarcoma

Kaposi Sarcoma, Susceptibility To

Kaposi'S Sarcoma Of Lung

Kaposi'S Sarcoma Of Palate

Kaposi'S Sarcoma Of Soft Tissue

Kaposi'S Sarcoma-Associated Herpesvirus

Multiple Idiopathic Pigmented Hemangiosarcoma

Multiple Idiopathic Pigmented Hemangiosarcoma, Susceptibility To

African Lymphadenopathic Kaposi'S Sarcoma

Anal Kaposi'S Sarcoma

Cardiac Kaposi'S Sarcoma

Central Nervous System Kaposi'S Sarcoma

Conjunctival Kaposi'S Sarcoma

Corneal Kaposi'S Sarcoma

Cutaneous Kaposi'S Sarcoma

Esophageal Kaposi'S Sarcoma

Gallbladder Kaposi'S Sarcoma

Gastric Kaposi'S Sarcoma

Intestinal Kaposi'S Sarcoma

Kaposi'S Sarcoma Of Anus

Kaposi'S Sarcoma Of Central Nervous System

Kaposi'S Sarcoma Of Conjunctiva

Kaposi'S Sarcoma Of Cornea

Kaposi'S Sarcoma Of Esophagus

Kaposi'S Sarcoma Of Gastrointestinal Sites

Kaposi'S Sarcoma Of Heart

Kaposi'S Sarcoma Of Lymph Nodes

Kaposi'S Sarcoma Of Penis

Kaposi'S Sarcoma Of Skin

Kaposi'S Sarcoma Of Soft Tissues

Kaposi'S Sarcoma Of The Cns

Kaposi'S Sarcoma Of The Gallbladder

Kaposi'S Sarcoma Of The Prostate

Kaposi'S Sarcoma, Lung

Kaposi'S Sarcoma, Skin

Lymph Node Kaposi'S Sarcoma

Lymphadenopathic Kaposi'S Sarcoma

Palate Kaposi'S Sarcoma

Penis Kaposi'S Sarcoma

Prostate Kaposi'S Sarcoma

Pulmonary Kaposi'S Sarcoma

Soft Tissue Kaposi'S Sarcoma

Hhv8

Human Herpesvirus 8

Kshv

Kaposi Sarcoma Herpesvirus

Mediterranean Kaposi Sarcoma

Non Aids Related Kaposi Sarcoma

Sarcoma, Kaposi

Sarcoma, Kaposi, Susceptibility To

Non-Aids-Related Kaposi Sarcoma

Angiolymphoid Hyperplasia

Angiofollicular Ganglionic Hyperplasia

Multi-Centric Castleman'S Disease

Suppressor Of Tumorigenicity 3

Cervical Carcinoma

ST3

Tumor-Suppressor Gene, Hela Cell Type

Tshl

Cervical Carcinoma, Tumor-Suppressor Gene Involved In

Ccts

Cervix Carcinoma

Gastric Cancer

Stomach Cancer

Gastric Carcinoma

Stomach Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach

Barrett Esophagus

Barrett'S Esophagus

Barrett Esophagus/Esophageal Adenocarcinoma

Barrett Metaplasia

Barrett'S Ulcer Of Esophagus

Ulcerative Esophagitis

Barrett'S Esophagus With Esophagitis

Barrett'S Oesophagus

Barretts Syndrome

Barrett Syndrome

BE

Peptic Ulcer Of Esophagus

Adenocarcinoma Of Esophagus

Plasmacytoma

Solitary Plasmacytoma

Solitary Myeloma

Myeloma - Solitary

Myeloma, Solitary

Plasmacytoma - Category

Solitary Osseous Plasmacytoma

Solitary Plasmacytoma Without Mention Of Remission

Localised Malignant Plasma Cell Tumour Nos

Plasmacytoma Nos

Esophageal Cancer

Esophageal Carcinoma

Carcinoma Of Esophagus

Esophageal Squamous Cell Carcinoma, Somatic

Esophageal Carcinoma, Somatic

Esophagus Cancer

Gastric Cardia Adenocarcinoma

Esophageal Neoplasms

Esophageal Cancer, Somatic

Cancer Of Esophagus

Cancer Of Oesophagus

Carcinoma Of Oesophagus

Ca Lower Third Oesophagus

Ca Middle Third Oesophagus

Malignant Neoplasm Of Distal Third Of Esophagus

Malignant Neoplasm Of Lower Third Of Oesophagus

Malignant Neoplasm Of Middle Third Of Oesophagus

Malignant Neoplasm Of Proximal Third Of Esophagus

Malignant Neoplasm Of Upper Third Esophagus

Malignant Tumor Of Abdominal Esophagus

Malignant Tumor Of Distal Third Of Esophagus

Malignant Tumor Of Proximal Third Of Esophagus

Malignant Tumor Of The Middle Third Of The Esophagus

ESCR

Aerodigestive Tract Cancer

Escc

Esophageal Squamous Cell Carcinoma

Cancer, Esophageal

Malignant Neoplasm Of Esophagus

Squamous Cell Carcinoma Of Esophagus

Malignant Neoplasm Of Middle Third Of Esophagus

Skin Melanoma

Cutaneous Melanoma

Malignant Ear Melanoma

Malignant Lip Melanoma

Malignant Lower Limb Melanoma

Malignant Melanoma Of Ear And/Or External Auricular Canal

Malignant Melanoma Of Skin Of Lower Limb

Malignant Melanoma Of Skin Of Trunk Except Scrotum

Malignant Melanoma Of Skin Of Upper Limb

Malignant Neck Melanoma

Malignant Scalp Melanoma

Malignant Trunk Melanoma

Malignant Upper Limb Melanoma

Melanoma, Cutaneous Malignant

Melanoma

Malignant Melanoma Of Skin

Melanoma Nos

Malignant Mole, Meaning Melanoma Of Unspecified Site

Melanoma Of Unspecified Site

Cutaneous Malignant Melanoma

Mm - [Malignant Melanoma]

Cheilitis
Burkitt Lymphoma

Burkitt'S Lymphoma

BL

Burkitt Lymphoma, Somatic

Burkitt Lymphoma/Leukaemia

Burkitt'S Tumor

Burkitt'S Tumor Or Lymphoma

Malignant Lymphoma, Burkitt'S Type

Small Non-Cleaved Cell Lymphoma, Burkitt'S Type

Small Non-Cleaved Cell Lymphoma

Burkitt Tumor

Burkitts Lymphoma

Lymphoma, Small Noncleaved-Cell

Burkitt Tumour

Diffuse Small Noncleaved Malignant Burkitt Lymphoma

Malignant Burkitt Lymphoma

“Burkitt-Like” Lymphoma

Undifferentiated Burkitt Lymphoma

Small Noncleaved Cell Burkitt Lymphoma

B-Cell Lymphoma

Lymphoma, B-Cell

B-Cell Lymphomas

B-Cell Lymphocytic Neoplasm

Lymphoma B-Cell

B-Cell Lymphoma Nos

Arthritis

Inflammatory Joint Disease

Inflammatory Disorder Of Joint

Prolactinoma

Prolactin-Producing Pituitary Gland Adenoma

Prolactin-Secreting Pituitary Adenoma

Forbes-Albright Syndrome

Lactotroph Adenoma

Prl-Secreting Pituitary Adenoma

Prloma

Pituitary Lactotrophic Adenoma

Familial Prolactinoma

Pituitary Adenoma, Prolactin-Secreting

Prolactinoma Of Pituitary Gland

PSPA

Shigellosis

Dysentery, Bacillary

Bacillary Dysentery

Shigella Boydii Infectious Disease

Shigella Flexneri Infectious Disease

Shigella Gastroenteritis

Shigella Sonnei Infectious Disease

Shigella Infections

Cockayne Syndrome

Cockayne'S Syndrome

Dwarfism-Retinal Atrophy-Deafness Syndrome

Neill-Dingwall Syndrome

Progeria-Like Syndrome

Progeroid Nanism

Cs

Basal Cell Carcinoma

Basal Cell Cancer

Basal Cell Neoplasm

Basal Cell Carcinoma Of Skin

Malignant Basal Cell Tumor

Basal Cell Tumor

Epithelioma Basal Cell

Malignant Basal Cell Neoplasm

Rodent Ulcer

Carcinoma Basal Cell

Neoplasms, Basal Cell

Basal Cell Carcinomas

Experimental Organism Basal Cell Carcinoma

Nodulo-Ulcerative Basal Cell Carcinoma

Basalioma

Basal Cell Epithelioma Of Skin

Bcc - [Basal Cell Carcinoma] Of Skin

Rodent Ulcer Of Skin

Rodent Ulcer Of Unspecified Site

Basal Cell Epithelioma Of Unspecified Site

Retinal Cancer

Malignant Neoplasm Of Retina

Retinal Neoplasms

Malignant Retinal Neoplasm

Malignant Tumor Of Retina

Neoplasm Of Retina

Retinal Tumor

Retinal Neoplasm

Cancer Of The Retina

Malignant Retinal Tumour

Malignant Tumour Of Retina

Primary Malignant Neoplasm Of Retina

Hepatoblastoma
Leukodystrophy, Hypomyelinating, 8, With Or Without Oligodontia And/Or Hypogonadotropic Hypogonadism

Hypomyelinating Leukodystrophy 8 With Or Without Oligodontia And-Or Hypogonadotropic Hypogonadism

HLD8

Cerebellar Hypoplasia With Endosteal Sclerosis

4h Leukodystrophy 2

Endosteal Sclerosis-Cerebellar Hypoplasia Syndrome

Leukodystrophy, Hypomyelinating, Type 8, With/Without Oligodontia And/Or Hypogonadotropic Hypogonadism

Brain Cancer

Adult Brain Tumor

Malignant Neoplasm Of Brain

Brain Neoplasms

Brain Neoplasm

Neoplasm Of Brain

Primary Malignant Neoplasm Of Brain

Brain Tumors

Adult Malignant Brain Neoplasm

Brain Neoplasm, Adult

Bt - Brain Tumour

Malignant Brain Tumour

Malignant Primary Brain Neoplasm

Malignant Primary Brain Tumor

Malignant Tumor Of Adult Brain

Malignant Tumor Of Brain

Primary Brain Neoplasm

Primary Brain Tumor

Tumor Of The Brain

Brain Tumor, Adult

Brain Tumor Primary

Malignant Primary Brain Tumors

Primary Brain Tumors

Cancer, Brain

Brain Tumor, Primary

Rhabdomyosarcoma
Cervical Squamous Cell Carcinoma

Squamous Cell Carcinoma Of The Cervix Uteri

Squamous Cell Carcinoma Of Cervix

Osteogenic Sarcoma

Osteosarcoma

OSRC

Osteosarcoma, Somatic

Neoplasms, Bone Tissue

Bone Tissue Neoplasm

Osteoid Sarcoma

Skeletal Sarcoma

Osteosarcoma Of Bone

Bone Sarcoma

High Grade Glioma

Malignant Glioma

Glial Cell Tumor

Glioma, Malignant

Malignant Neuroglial Tumor

Neuroglial Tumor

Glioma

Malignant Gliomas

Leukemia, Chronic Myeloid

Chronic Myeloid Leukemia

Chronic Myelogenous Leukemia

CML

Chronic Granulocytic Leukemia

Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib

Chronic Myeloid Leukaemia

Chronic Granulocytic Leukaemia

Chronic Myelogenous Leukaemia

Myeloid Leukemia, Chronic

Leukemia, Chronic Myelogenous

Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic

Cml - Chronic Myelogenous Leukemia

Cgl

Chronic Myelocytic Leukemia

Leukemia, Chronic Myeloid, Atypical

ACML

Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative

Myeloid Leukemia Chronic

Leukemia, Myeloid, Chronic

Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative

Cml- [Chronic Myeloid Leukaemia]

Cgl - [Chronic Granulocytic Leukaemia]

Chronic Myelocytic Leukaemia

Lung Cancer Susceptibility 3

Lung Adenocarcinoma

Adenocarcinoma Of Lung

LNCR3

Adenocarcinoma Of Lung, Susceptibility To

Bronchogenic Lung Adenocarcinoma

Nonsmall Cell Adenocarcinoma

Adenocarcinoma Lung

Lung Adenocarcinomas

Non-Small Cell Adenocarcinoma

Medulloblastoma

MDB

Cpnet

Localized Primitive Neuroectodermal Tumor

Classic Medulloblastoma

Medulloblastoma Predisposition Syndrome

Medulloblastoma, Somatic

Brain Medulloblastoma

Cns Pnet

Infratentorial Primitive Neuroectodermal Tumor

Neuroectodermal Tumors, Primitive

Medulloblastomas

Desmoplastic Medulloblastoma

Medulloblastoma, With Extensive Nodularity

Medulloblastoma Of Unspecified Site

Medullomyoblastoma Of Unspecified Site

Ocular Cancer

Eye Neoplasm

Eye Carcinoma

Eye Cancer

Eye Neoplasms

Malignant Eye Neoplasm

Neoplasm Of Eye

Neoplasm Of Eye Proper

Ocular Tumor

Carcinoma Of Eye

Ocular Carcinoma

Malignant Tumor Of Eye

Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma

Skin Papilloma

Cutaneous Papilloma

Papilloma Of Skin

Papilloma Skin

Squamous Cell Carcinoma, Head And Neck

Squamous Cell Carcinoma Of The Head And Neck

HNSCC

Head And Neck Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Lip

Squamous Cell Carcinoma, Head And Neck, Somatic

Carcinoma Of The Head And Neck

Squamous Cell Carcinomas Of Head And Neck

Scchn

Squamous Cell Carcinoma Of The Hypopharynx

Squamous Cell Carcinoma Of The Oropharynx

Squamous Cell Carcinoma Of Salivary Glands

Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses

Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses

Squamous Cell Carcinoma Of The Oral Cavity

Squamous Cell Carcinoma Of The Lip

Carcinoma, Squamous Cell Of Head And Neck

Lip Squamous Cell Carcinoma

Carcinoma, Squamous Cell, Head And Neck

Salivary Gland Squamous Cell Carcinoma

Cancer Of Head And Neck

Squamous Cell Carcinoma Of Oropharynx Nos

Pheochromocytoma

Pheochromocytoma, Susceptibility To

Phaeochromocytoma

Adrenal Gland Chromaffin Paraganglioma

Adrenal Gland Chromaffinoma

Adrenal Gland Paraganglioma

Adrenal Gland Pheochromocytoma

Chromaffin Paraganglioma Of The Adrenal Gland

Intraadrenal Paraganglioma

PCC

Chromaffin Cell Tumor

Medullary Chromaffinoma

Medullary Paraganglioma

Pheochromoblastoma

Pheochromocytomas

Chromaffin Cell Neoplasm

Pheochromocytoma, Malignant

Lung Adenoma

Adenoma Of Lung

Pulmonary Adenoma

Muscular Dystrophy

Muscular Dystrophies

Congenital Md

Congenital Muscular Dystrophy

Cmd

Mdc

Dystrophy, Muscular

Gower'S Muscular Dystrophy

Progressive Musclular Dystrophy

Pseudohypertrophic Atrophy

Pseudohypertrophic Muscle Paralysis

Pseudohypertrophic Muscular Atrophy

Pseudohypertrophic Muscular Dystrophy

Pseudohypertrophic Paralysis

Pseudomuscular Hypertrophy

Thrombocytopenia

Low Platelet Count

Low Platelets

Decreased Platelets

Platelet Dysfunction Nos

Retinal Disease

Retinal Diseases

Retinal Disorder

Retinal Disorders

Myeloma, Multiple

Multiple Myeloma

Plasma Cell Myeloma

Kahler Disease

Myelomatosis

Medullary Plasmacytoma

Multiple Myeloma, Resistance To

Myeloma

Plasma Cell Dyscrasia

Kahler'S Disease

Multiple Myeloma, Susceptibility To

Myeloma - Multiple

Kahler-Bozzolo Disease

Plasma Cell Myelomas

MM

Plasma Cell Neoplasm

Primary Systemic Amyloidosis

Primary Amyloidosis

Immunoglobulin Deposition Disease

Plasmacytic Myeloma

Multiple Myelomata

Multiple Myeloma Nos

Multiple Myeloma Without Mention Of Remission

Monostotic Plasma Cell Myeloma

Mm - [Multiple Myeloma]

Melanoma, Cutaneous Malignant 1

Familial Melanoma

Melanoma, Cutaneous Malignant, Susceptibility To, 1

Melanoma, Malignant

CMM1

Melanoma, Cutaneous Malignant

Cmm

Familial Atypical Mole-Malignant Melanoma Syndrome

Fammm

Melanoma, Familial

Mlm

Dysplastic Nevus Syndrome, Hereditary

Dns

B-K Mole Syndrome

Melanoma, Cutaneous Malignant, 1

Malignant Melanoma, Cutaneous

Melanoma, Cutaneous, Malignant, Susceptibility To, Type 1

Dysplastic Nevus Syndrome

Cutaneous Melanoma

Familial Atypical Mole Melanoma Syndrome

Hereditary Melanoma

Fanconi Anemia, Complementation Group A

Fanconi Anemia

Fanconi Pancytopenia

Fanconi Anemia Complementation Group A

FANCA

Fa

Fanconi Panmyelopathy

Fanconi'S Anemia

Fanconi Anaemia

Fanconi'S Anaemia

Fanconi Hypoplastic Anemia

Estren-Dameshek Variant Of Fanconi Anemia

Estren-Dameshek Variant Of Fanconi Pancytopenia

Fanconi Anemia Estren-Dameshek Variant

Fanconis Anemia

Colonic Benign Neoplasm

Colon Neoplasm

Colonic Mass

Colonic Tumor

Neoplasm Of Colon

Neoplasm Of The Colon

Colonic Neoplasms

Colon Cancer

Colon Carcinoma Nos

Colonic Cancer

Metastatic Colon Cancer Nos

Breast Adenocarcinoma

Mammary Adenocarcinoma

Adenocarcinoma Of Breast

Eye Disease

Eye Diseases

Abnormality Of The Eye

Toxoplasma Oculopathy

Leukemia, Acute Myeloid

Acute Myeloid Leukemia

Leukemia, Acute Myelogenous

Acute Myelogenous Leukemia

AML

Leukemia, Acute Myeloid, Susceptibility To

Acute Myeloblastic Leukemia

Leukemia, Acute Myeloid, Reduced Survival In, Somatic

Acute Myeloid Leukaemia

Leukemia, Myelocytic, Acute

Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

Secondary Aml

Acute Myelocytic Leukemia

Acute Myeloid Leukemia, Somatic

Leukemia, Acute Myeloid, Somatic

Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

Acute Myeloblastic Leukaemia

Acute Myelogenous Leukaemia

Aml - Acute Myeloid Leukemia

Acute Myeloid Leukemia With Cebpa Somatic Mutations

Aml With Cebpa Somatic Mutations

Inherited Acute Myeloid Leukemia

Familial Aml

Inherited Aml

Pure Familial Aml

Pure Familial Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

Therapy-Related Aml And Myelodysplastic Syndrome

Acute Myeloid Leukemia, Secondary

Acute Non-Lymphoblastic Leukemia

Acute Non-Lymphocytic Leukemia

Acute Biphenotypic Leukemia

Acute Undifferentiated Leukemia

Acute Myeloblastic Leukaemia With Multilineage Dysplasia

Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus CDKN1A VGNC VGNC:60713
Mus musculus CDKN1A MGD MGI:104556
Bos taurus CDKN1A VGNC VGNC:27142
Canis familiaris CDKN1A VGNC VGNC:39068
Rattus norvegicus CDKN1A RGD RGD:69328
Macaca mulatta CDKN1A VGNC VGNC:70988
Others CDKN1A NCBI