Search Result

Results for "

Anticholinergic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (3) Adrenergic Receptor (7) Apoptosis (3) Autophagy (2) Bacterial (4) Calcium Channel (9) Cholinesterase (ChE) (21) Cytochrome P450 (1) Dopamine Receptor (12) Dopamine Transporter (1) Drug Metabolite (2) Endogenous Metabolite (8) Histamine Receptor (30) iGluR (8) Influenza Virus (1) Isotope-Labeled Compounds (11) mAChR (78) mGluR (1) Mitophagy (2) NF-κB (2) NO Synthase (1) Opioid Receptor (4) Phosphodiesterase (PDE) (2) Potassium Channel (12) Sodium Channel (4)
By Research Areas:	Cancer (18) Cardiovascular Disease (5) Endocrinology (16) Infection (1) Inflammation/Immunology (31) Metabolic Disease (9) Neurological Disease (128)

By Targets:

5-HT Receptor (3)

Adrenergic Receptor (7)

Apoptosis (3)

Autophagy (2)

Bacterial (4)

Calcium Channel (9)

Cholinesterase (ChE) (21)

Cytochrome P450 (1)

Dopamine Receptor (12)

Dopamine Transporter (1)

Drug Metabolite (2)

Endogenous Metabolite (8)

Histamine Receptor (30)

iGluR (8)

Influenza Virus (1)

Isotope-Labeled Compounds (11)

mAChR (78)

mGluR (1)

Mitophagy (2)

NF-κB (2)

NO Synthase (1)

Opioid Receptor (4)

Phosphodiesterase (PDE) (2)

Potassium Channel (12)

Sodium Channel (4)

By Research Areas:

Cancer (18)

Cardiovascular Disease (5)

Endocrinology (16)

Infection (1)

Inflammation/Immunology (31)

Metabolic Disease (9)

Neurological Disease (128)

167

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0527

Amitriptyline 4 Publications Verification	Others	Metabolic Disease
Amitriptyline is a common oral anticholinergic. Amitriptyline has anticholinergic properties. Amitriptyline can be used to quantify anticholinergic adverse reactions in patients taking amitriptyline and placebo .

HY-B0547A

Homatropine Bromide	mAChR	Neurological Disease
Homatropine Bromide is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent .

HY-121773

Metoquizine	mAChR	Neurological Disease
Metoquizine is an anticholinergic agent .

HY-117633

Sultroponium Atropine sulfobetaine; A-118	Cholinesterase (ChE)	Neurological Disease
Sultroponium (A118) is an anticholinergic agent .

HY-108030

Bencycloquidium bromide	mAChR	Neurological Disease Inflammation/Immunology Cancer
Bencycloquidium bromide, a muscarinic M(3) receptor antagonist, is an anticholinergic compound that acts as an anticholinergic bronchodilator. Bencycloquidium bromide can be used in the study for rhinitis .

HY-W008613A

Amitriptyline pamoate	Others	Metabolic Disease Cancer
Amitriptyline pamoate is a common oral anticholinergic. Amitriptyline pamoate has anticholinergic properties. Amitriptyline pamoate can be used to quantify anticholinergic adverse reactions in patients taking amitriptyline and placebo .

HY-B0547

Homatropine	mAChR	Neurological Disease
Homatropine is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent .

HY-43711

Nor-benzetimide	mAChR	Neurological Disease
Nor-benzetimide is a major metabolite of Benzetimide. Benzetimide is a mAChR antagonist with anticholinergic activity .

HY-106601

Picenadol LY-150720	Opioid Receptor	Neurological Disease
Picenadol (LY-150720) is a racemic opioid that can be used in combination with other opioids. Picenadol has anticholinergic activity .

HY-B1542

Benactyzine	Cholinesterase (ChE)	Neurological Disease
Benactyzine is a competitive BChE inhibitor with a K_i of 0.01 mM. Benactyzine is an anticholinergic drug. Benactyzine has the potential for organophosphate poisoning research .

HY-105771

Parapenzolate bromide	mAChR	Neurological Disease
Parapenzolate bromide, an antispasmodic, is an orally active mAChR antagonist. Parapenzolate bromide is an anticholinergic agent .

HY-B0547AR

Homatropine Bromide (Standard)	mAChR	Neurological Disease
Homatropine (Bromide) (Standard) is the analytical standard of Homatropine (Bromide). This product is intended for research and analytical applications. Homatropine Bromide is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent .

HY-118406

Ethybenztropine Ponalid; UK 738	mAChR	Neurological Disease
Ethybenztropine (Ponalid) is a muscarinic receptor blocker. Ethybenztropine is an anticholinergic and antihistaminergic agent .

HY-105545

Dexetimide (+)-Benzetimide; (S)-(+)-Dexetimide; Dexbenzetimide	mAChR	Neurological Disease
Dexetimide ((+)-Benzetimide; (S)-(+)-Dexetimide; Dexbenzetimide) is a piperidine anticholinergic and a high-affinity muscarinic receptor antagonist. Dexetimide can be used in studies of parkinson's disease .

HY-B1343

Pridinol mesylate	Cholinesterase (ChE)	Neurological Disease
Pridinol mesylate is an orally active and potent central *anticholinergic* agent, and acts as muscle relaxant .

HY-B1343A

Pridinol	Cholinesterase (ChE)	Neurological Disease
Pridinol is an orally active and potent central *anticholinergic* agent, and acts as muscle relaxant .

HY-105744

Leiopyrrole DV-714	Others	Neurological Disease
Leiopyrrole (DV-714), a 2-arylated pyrrole derivative, is an anticholinergic agent .

HY-N7061

Tropine	Others	Neurological Disease
Tropine is a secondary metabolite of Solanaceae plants, is an *anticholinergic* agent . Tropine is a common intermediate in the synthesis of a variety of bioactive alkaloids, including hyoscyamine and scopolamine .

HY-B2112

Valethamate bromide	Others	Others
Valethamate bromide is an ester and is a potent rapidly acting anticholinergic spasmolytic and musculotropic agent which accelerates labor by improving cervical dilation .

HY-117284

Eucatropine	mAChR	Neurological Disease
Eucatropine is a potent muscarinic acetylcholine receptor (mAChR) inhibitor with an IC₅₀ value of 0.583 μM. Eucatropine is an anticholinergic agent .

HY-B1806A

Tridihexethyl chloride Pathilon chloride	mAChR	Neurological Disease Inflammation/Immunology
Tridihexethyl (Pathilon) chloride is an orally active *anticholinergic* agent and mAChR antagonist, shows activities of antimuscarinic and anticholinergic. Tridihexethyl chloride shows pronounced antispasmodic and antisecretory effects on the gastrointestinal tract. Tridihexethyl chloride can be used in studies of peptic ulcer disease and acquired nystagmus .

HY-B1343R

Pridinol mesylate (Standard)	Cholinesterase (ChE)	Neurological Disease
Pridinol (mesylate) (Standard) is the analytical standard of Pridinol (mesylate). This product is intended for research and analytical applications. Pridinol mesylate is an orally active and potent central *anticholinergic* agent, and acts as muscle relaxant .

HY-135407S

N-Desethyl Oxybutynin-d5 hydrochloride	Isotope-Labeled Compounds Drug Metabolite	Neurological Disease
N-Desethyl Oxybutynin-d₅ (hydrochloride) is deuterium labeled N-Desethyl Oxybutynin hydrochloride. N-Desethyl Oxybutynin is the the active metabolite Oxybutynin. Oxybutynin is an anticholinergic agent that inhibits voltage-dependent K+ channels[1].

HY-116550

Piroheptine hydrochloride	Dopamine Transporter	Neurological Disease
Piroheptine hydrochloride is an anticholinergic agent to inhibit dopamine uptake. Piroheptine hydrochloride prevents loss of striatal dopamine induced by MPTP (HY-15608). Piroheptine hydrochloride can be used for research in Parkinson .

HY-B1475

Anisotropine bromide Octatropine bromide	mAChR	Neurological Disease Metabolic Disease
Anisotropine (Octatropine) bromide is an orally active *anticholinergic* muscarinic antagonist. Anisotropine bromide can inhibit gastric acid secretion and is used as an adjunct to peptic ulcers .

HY-N7061R

Tropine (Standard)	Others	Neurological Disease
Tropine (Standard) is the analytical standard of Tropine. This product is intended for research and analytical applications. Tropine is a secondary metabolite of Solanaceae plants, is an anticholinergic agent . Tropine is a common intermediate in the synthesis of a variety of bioactive alkaloids, including hyoscyamine and scopolamine .

HY-118406B

Ethybenztropine hydrobromide Ponalid hydrobromide; UK 738 hydrobromide	mAChR	Neurological Disease
Ethybenztropine hydrobromide (Ponalid hydrobromide) is an anticholinergic drug with antiparkinsonian activity. Ethybenztropine hydrobromide may also act as a dopamine reuptake inhibitor. Ethybenztropine hydrobromide is commonly used to suppress Parkinson's disease .

HY-105853

Pitofenone	Others	Neurological Disease
Pitofenone is an orally active antispasmodic agent with *anticholinergic* and musculotropic activities in various smooth muscles. Pitofenone can be utilized in spasm research .

HY-167649

Poskine	Others	Neurological Disease
Poskine is an anticholinergic agent and a central nervous system depressant. Poskine can be utilized in research related to Parkinson's disease and travel sickness .

HY-117501

Dexchlorpheniramine	Histamine Receptor	Inflammation/Immunology
Dexchlorpheniramine is an potent and blood-brain barrier (BBB) penetrant histamine 1 (H1) receptor antagonist with anticholinergic properties. Dexchlorpheniramine can be used for researching allergies .

HY-B0761

(R,R)-Glycopyrrolate (R,R)-Glycopyrronium bromide; (R,R)-Glycopyrrolate bromide	mAChR	Neurological Disease
(R,R)-Glycopyrrolate ((R,R)-Glycopyrronium (bromide); (R,R)-Glycopyrrolate (bromide)) is an *anticholinergic* agent. (R,R)-Glycopyrrolate ((R,R)-Glycopyrronium (bromide); (R,R)-Glycopyrrolate (bromide)) has the ability to reduce the frequency of drooling in vivo with developmental disabilities .

HY-107922

Ethopropazine hydrochloride Isothazine hydrochloride; Lysivane hydrochloride; Parsidol hydrochloride	Cholinesterase (ChE)	Neurological Disease
Ethopropazine (Isothazine) hydrochloride is a potent, selective BChE inhibitor and a poor AChE inhibitor. Ethopropazine hydrochloride is a phenothiazine compound with anticholinergic properties. Ethopropazine hydrochloride can be used for the research of Parkinson’s disease .

HY-B1667

Isopropamide iodide	Others	Metabolic Disease
Isopropamide iodide is a long-acting quaternary anticholinergic agent. Isopropamide iodide is used in peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility .

HY-14786

Darotropium bromide GSK233705	mAChR	Neurological Disease Inflammation/Immunology
Darotropium bromide (GSK233705), a long-acting muscarinic antagonist and an inhaled anticholinergic, can be used for the research of chronic obstructive pulmonary disease (COPD) .

HY-118406A

Ethybenztropine hydrochloride Ponalid hydrochloride; UK 738 hydrochloride	mAChR	Neurological Disease
Ethybenztropine hydrochloride (Ponalid hydrochloride) is an anticholinergic drug with antiparkinsonian activity. Ethybenztropine hydrochloride may also have dopamine reuptake inhibitory effects. Ethybenztropine hydrochloride is used to improve motor symptoms in patients with Parkinson's disease. Ethybenztropine hydrochloride exerts its inhibitory effects by regulating the balance of neurotransmitters .

HY-116408A

Propiverine hydrochloride	mAChR Calcium Channel	Neurological Disease
Propiverine hydrochloride is a bladder spasmolytic with calcium antagonistic and anticholinergic properties. Propiverine hydrochloride can be used for the research of overactive blaqdder and urinary incontinence .

HY-B0548AS

Hydroxyzine D4 dihydrochloride	Histamine Receptor	Neurological Disease Inflammation/Immunology Endocrinology
Hydroxyzine-d₄ (dihydrochloride) is deuterium labeled Hydroxyzine. Hydroxyzine is a heterocyclic histamine H1-receptor antagonist. Hydroxyzine has anticholinergic, anxiolytic and analgesic properties[1].

HY-105790

Piperilate Pipethanate	Cholinesterase (ChE)	Cardiovascular Disease
Piperilate (Pipethanate) is one of the mixtures of hetrazepine derivative PAF antagonists with anticholinergics, can be used for bronchial asthma research. Piperilate also causes hypotension and rescues mice poisoned by the organophosphates .

HY-105790A

Piperilate hydrochloride	Cholinesterase (ChE)	Cardiovascular Disease
Piperilate (Pipethanate) hydrochloride is one of the mixtures of hetrazepine derivative PAF antagonists with anticholinergics, can be used for bronchial asthma research. Piperilate hydrochloride also causes hypotension and rescues mice poisoned by the organophosphates .

HY-B1483

Methapyrilene hydrochloride Thenylpyramine hydrochloride	Histamine Receptor	Inflammation/Immunology
Methapyrilene (Thenylpyramine) hydrochloride is an orally active H1-receptor antihistamine and an anticholinergic agent of the pyridine chemical class. Methapyrilene hydrochloride has hepatotoxicity and can be used as a hepatotoxin that cause periportal hepatic necrosis in vivo

HY-107922R

Ethopropazine hydrochloride (Standard)	Cholinesterase (ChE)	Neurological Disease
Ethopropazine (hydrochloride) (Standard) is the analytical standard of Ethopropazine (hydrochloride). This product is intended for research and analytical applications. Ethopropazine (Isothazine) hydrochloride is a potent, selective BChE inhibitor and a poor AChE inhibitor. Ethopropazine hydrochloride is a phenothiazine compound with anticholinergic properties. Ethopropazine hydrochloride can be used for the research of Parkinson’s disease .

HY-106564A

Flutropium bromide Ba 598Br; Flubron	Others	Inflammation/Immunology
Flutropium bromide (Ba 598Br) is a organic bromide salt of flutropium. Flutropium bromide shows an anticholinergic effect. Flutropium bromide effectively suppresses spasms and it can be used for the research of asthma and chronic obstructive pulmonary disease .

HY-14263

Pericyazine Propericiazine; RP 8909	Dopamine Receptor	Neurological Disease
Pericyazine (Propericiazine) is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis . Pericyazine is a selective D2-dopamine receptor antagonist . Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects .

HY-111130

Methapyrilene	Histamine Receptor mAChR	Neurological Disease Cancer
Methapyrilene is a histamine antagonist, a pyridine chemical with anticholinergic activity. Methapyrilene can cause target organ-specific epigenetic alterations, such as a decrease in DNA methylation levels. Methapyrilene induces hepatocellular carcinoma in rats .

HY-16489

Terodiline	Potassium Channel mAChR Calcium Channel	Metabolic Disease
Terodiline, an antispasmodic agent, blocks hERG current with the IC₅₀ of 375 nM. Terodiline has both *anticholinergic* and calcium antagonist properties, and effectively reduces abnormal bladder contractions caused by detrusor instability. Terodiline can be used for the research of urinary incontinence .

HY-B1667R

Isopropamide iodide (Standard)	Others	Metabolic Disease
Isopropamide (iodide) (Standard) is the analytical standard of Isopropamide (iodide). This product is intended for research and analytical applications. Isopropamide iodide is a long-acting quaternary anticholinergic agent. Isopropamide iodide is used in peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility .

HY-N9337

Amaroswerin	NO Synthase	Metabolic Disease Inflammation/Immunology Cancer
Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC₅₀ value of 5.42 μg/mL in RAW264.7 cells .

HY-B0520A

Benztropine mesylate 5 Publications Verification Benzatropine mesylate; Benzotropine mesylate; Benztropine methanesulfonate	Dopamine Receptor mAChR Histamine Receptor	Neurological Disease Cancer
Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D₂ dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects .

HY-109013

Sofpironium bromide BBI 4000	mAChR	Neurological Disease
Sofpironium bromide (BBI 4000) is an anticholinergic agent used in the study of primary axillary hyperhidrosis (PAH). Sofpironium bromide reduces sweating by inhibiting M3 muscarinic receptors in eccrine glands at the application site. Sofpironium bromide also has a high afnity for the M1, M2, M4 and M5 subtypes .

HY-120081A

Metixene hydrochloride hydrate 1 Publications Verification	Others	Neurological Disease
Metixene (Piperidine) hydrochloride hydrate is an anticholinergic and antiparkinsonian agent. Metixene hydrochloride hydrate potently inhibits binding of quinuclidinyl benzilate (QNB) with the muscarinic receptor, IC₅₀ and K_i values of 55 nM and 15 nM, respectively. Metixene hydrochloride hydrate can be used for the research of parkinsonian .

Cat. No.	Product Name	Type

HY-W354753

Homatropine hydrochloride	Biochemical Assay Reagents
Homatropine hydrochloride is an orally active anticholinergic agent that rapidly dilates pupils and has cycloplegic effects. Homatropine hydrochloride also has antitussive activity. Homatropine hydrochloride can be used in research on eye diseases and coughs .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7061

Tropine	Alkaloids Structural Classification Microorganisms Other Alkaloids Source classification Plants Solanaceae Przewalskia tangutica Maximo.	Others
Tropine is a secondary metabolite of Solanaceae plants, is an *anticholinergic* agent . Tropine is a common intermediate in the synthesis of a variety of bioactive alkaloids, including hyoscyamine and scopolamine .

HY-N9337

Amaroswerin	Iridoids Classification of Application Fields Terpenoids Source classification Gentianaceae Phenols Polyphenols Metabolic Disease Swertia mussotii Franch. Plants Disease Research Fields Inflammation/Immunology	NO Synthase
Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC₅₀ value of 5.42 μg/mL in RAW264.7 cells .

HY-U00082

Tigloidin Tigloyl pseudotropine; Tiglylpseudotropine; Tiglyssin	Alkaloids Classification of Application Fields Datura innoxia Miller Source classification Plants Solanaceae Disease Research Fields Inflammation/Immunology	Others
Tigloidin is an analogue of atropine, with anticholinergic activity.

HY-B0303A

Diphenhydramine hydrochloride 5 Publications Verification	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Histamine Receptor Endogenous Metabolite Bacterial Apoptosis
Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-B0303

Diphenhydramine 5 Publications Verification	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Histamine Receptor Bacterial Endogenous Metabolite iGluR
Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-N6608

Physostigmine 1 Publications Verification Eserine	Alkaloids Lablab purpureus (L.) Sweet Leguminosae Source classification Plants Indole Alkaloids	Cholinesterase (ChE)
Physostigmine (Eserine) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine is also an antidote for anticholinergic poisoning .

HY-N7061R

Tropine (Standard)	Alkaloids Structural Classification Microorganisms Other Alkaloids Source classification Solanaceae Plants Przewalskia tangutica Maximo.	Others
Tropine (Standard) is the analytical standard of Tropine. This product is intended for research and analytical applications. Tropine is a secondary metabolite of Solanaceae plants, is an anticholinergic agent . Tropine is a common intermediate in the synthesis of a variety of bioactive alkaloids, including hyoscyamine and scopolamine .

HY-105790

Piperilate Pipethanate	Cardiovascular Disease Classification of Application Fields Disease Research Fields	Cholinesterase (ChE)
Piperilate (Pipethanate) is one of the mixtures of hetrazepine derivative PAF antagonists with anticholinergics, can be used for bronchial asthma research. Piperilate also causes hypotension and rescues mice poisoned by the organophosphates .

HY-B0303R

Diphenhydramine (Standard)	Structural Classification Alkaloids Other Alkaloids Source classification Endogenous metabolite	Histamine Receptor Bacterial Endogenous Metabolite iGluR
Diphenhydramine (Standard) is the analytical standard of Diphenhydramine. This product is intended for research and analytical applications. Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) .

HY-N0584B

Anisodamine hydrochloride 6-Hydroxyhyoscyamine hydrochloride	Structural Classification Alkaloids Pyrrole Alkaloids Anisodus tanguticus (Maxinowicz) Pascher Source classification Plants Solanaceae	Adrenergic Receptor
Anisodamine hydrochloride is an anticholinergic and α1 adrenergic receptor antagonist. Anisodamine hydrochloride can be used for improving blood flow in circulatory disorders such as septic shock, Anisodamine hydrochloride displays a spectrum of pharmacological effects similar to Atropine (HY-B1205) and Sopolamine (HY-B2065) including inhibition of salivation, gastrointestinal and sweat secretion, gastrointestinal motility, respiratory secretion and urinary bladder contraction in vivo .

Cat. No.	Product Name	Chemical Structure

HY-B0267AS

Oxybutynin-d11 chloride
Oxybutynin-d₁₁ (chloride) is the deuterium labeled Oxybutynin chloride. Oxybutynin chloride is an anticholinergic agent, which inhibits vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM[1].

HY-B0303AS1

Diphenhydramine-d5 hydrochloride
Diphenhydramine-d₅ (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].

HY-B0303AS

Diphenhydramine-d6 hydrochloride
Diphenhydramine-d₆ (hydrochloride) is the deuterium labeled Diphenhydramine hydrochloride. Diphenhydramine hydrochloride is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB)[1][2].

HY-135407S

N-Desethyl Oxybutynin-d5 hydrochloride
N-Desethyl Oxybutynin-d₅ (hydrochloride) is deuterium labeled N-Desethyl Oxybutynin hydrochloride. N-Desethyl Oxybutynin is the the active metabolite Oxybutynin. Oxybutynin is an anticholinergic agent that inhibits voltage-dependent K+ channels[1].

HY-B0548AS

Hydroxyzine D4 dihydrochloride
Hydroxyzine-d₄ (dihydrochloride) is deuterium labeled Hydroxyzine. Hydroxyzine is a heterocyclic histamine H1-receptor antagonist. Hydroxyzine has anticholinergic, anxiolytic and analgesic properties[1].

HY-B0267BS

Oxybutynin-d5 hydrochloride

Oxybutynin-d₅ hydrochloride is deuterated labeled (R)-Oxybutynin hydrochloride (HY-B0267B). (R)-Oxybutynin hydrochloride, a (R)-isomer of Oxybutynin hydrochloride, is an orally active muscarinic receptor antagonist. (R)-Oxybutynin hydrochloride has antimuscarinic, antispasmodic and anticholinergic activity, competitively antagonizes Carbachol-induced contractions. (R)-Oxybutynin hydrochloride can be used for researching incontinence due to neurogenic bladder dysfunction . (R)-Oxybutynin hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-133153S

Fenpiverinium-d3 bromide
Fenpiverinium-d₃ (bromide) is a deuterium labeled Fenpiverinium bromide. Fenpiverinium bromide has anti-cholinergic and anti-spasmodic effects[1].

HY-116408AS

Propiverine-d7 hydrochloride
Propiverine-d₇ (hydrochloride) is the deuterium labeled Propiverine hydrochloride. Propiverine hydrochloride is a bladder spasmolytic with calcium antagonistic and anticholinergic properties. Propiverine hydrochloride can be used for the research of overactive blaqdder and urinary incontinence[1][2].

HY-B1470S

Azaperone-d4
Azaperone-d₄ is the deuterium labeled Azaperone. Azaperone (R-1929) acts as a dopamine antagonist but also has some antihistaminic and anticholinergic properties. Azaperone is a pyridinylpiperazine and butyrophenone neuroleptic agent with antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.

HY-B1296S1

Promethazine-d4
Promethazine-d4 is a deuterated-labeled promethazine (HY-B0781). Promethazine is an orally active H1 receptor and mAChR antagonist with antihistamine (H1), sedative, antiemetic, anticholinergic, and anti-motion sickness properties .

HY-N6608S

Physostigmine-d3

Physostigmine-d₃ is the deuterium labeled Physostigmine. Physostigmine (Eserine) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine is also an antidote for anticholinergic poisoning[1][2][3][4].

HY-108974S

Drotaverine-d10 hydrochloride

Drotaverine-d₁₀ (hydrochloride) is the deuterium labeled Drotaverine hydrochloride. Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3',5'-cyclic adenosine monophosphate. Drotaverine hydrochloride exhibits in vivo antispasmodic efficacy without anticholinergic effects[1][2].

HY-B0520AS1

Benztropine-d3 mesylate

Benztropine-d₃ (mesylate) is the deuterium labeled Benztropine mesylate[1]. Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects[2][3].

HY-B0520AS

Benztropine-13C,d3 mesylate

Benztropine- ¹³C,d₃ (mesylate) is the ¹³C- and deuterium labeled Benztropine (mesylate). Benztropine mesylate (Benzatropine mesylate) is an orally active centrally acting anticholinergic agent that can be used for Parkinson's disease research. Benztropine mesylate is an anti-histamine agent and a dopamine re-uptake inhibitor. Benztropine mesylate is also a human D2 dopamine receptor allosteric antagonist. Benztropine mesylate also has anti-CSCs (cancer stem cells) effects[1][2].

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks