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Cycloguanil

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (2) Antibiotic (4) Antifolate (8) Apoptosis (4) Arrestin (2) Bacterial (20) Biochemical Assay Reagents (6) CXCR (2) Deubiquitinase (1) Drug Metabolite (4) EGFR (1) Endogenous Metabolite (1) Endothelin Receptor (2) ERK (1) Estrogen Receptor/ERR (1) Fungal (3) GHSR (1) HCV (1) HIF/HIF Prolyl-Hydroxylase (4) IFNAR (1) Integrin (11) Isotope-Labeled Compounds (4) MMP (2) Neurokinin Receptor (2) NF-κB (2) Nuclear Factor of activated T Cells (NFAT) (1) Opioid Receptor (2) Oxytocin Receptor (1) Parasite (11) PD-1/PD-L1 (1) PI3K (1) Proteasome (2) Radionuclide-Drug Conjugates (RDCs) (1) Raf (1) Ras (1) Reactive Oxygen Species (1) Somatostatin Receptor (5) STAT (1) Tyrosinase (1) Vasopressin Receptor (1) VEGFR (2)
By Research Areas:	Cancer (42) Cardiovascular Disease (5) Endocrinology (4) Infection (34) Inflammation/Immunology (14) Metabolic Disease (7) Neurological Disease (6)

By Targets:

Adrenergic Receptor (2)

Antibiotic (4)

Antifolate (8)

Apoptosis (4)

Arrestin (2)

Bacterial (20)

Biochemical Assay Reagents (6)

CXCR (2)

Deubiquitinase (1)

Drug Metabolite (4)

EGFR (1)

Endogenous Metabolite (1)

Endothelin Receptor (2)

ERK (1)

Estrogen Receptor/ERR (1)

Fungal (3)

GHSR (1)

HCV (1)

HIF/HIF Prolyl-Hydroxylase (4)

IFNAR (1)

Integrin (11)

Isotope-Labeled Compounds (4)

MMP (2)

Neurokinin Receptor (2)

NF-κB (2)

Nuclear Factor of activated T Cells (NFAT) (1)

Opioid Receptor (2)

Oxytocin Receptor (1)

Parasite (11)

PD-1/PD-L1 (1)

PI3K (1)

Proteasome (2)

Radionuclide-Drug Conjugates (RDCs) (1)

Raf (1)

Ras (1)

Reactive Oxygen Species (1)

Somatostatin Receptor (5)

STAT (1)

Tyrosinase (1)

Vasopressin Receptor (1)

VEGFR (2)

By Research Areas:

Cancer (42)

Cardiovascular Disease (5)

Endocrinology (4)

Infection (34)

Inflammation/Immunology (14)

Metabolic Disease (7)

Neurological Disease (6)

Inhibitors & Agonists

123

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12784A

Cycloguanil hydrochloride	Parasite Drug Metabolite	Infection
Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes .

HY-12784S

Cycloguanil-d6 1 Publications Verification Chlorguanide triazine-d₆	Antifolate	Others
Cycloguanil-d₆6 is the deuterium labeled Cycloguanil, which is a dihydrofolate reductase inhibitor.

HY-B0806

Proguanil 1 Publications Verification	Parasite Antifolate	Infection
Proguanil, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil is a dihydrofolate reductase (DHFR) inhibitor .

HY-B0806A

Proguanil hydrochloride 1 Publications Verification	Parasite Antifolate	Infection
Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor .

HY-12784

*Cycloguanil*	Parasite Drug Metabolite	Infection
Cycloguanil, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes .

HY-12784AS1

Cycloguanil-d6 hydrochloride	Isotope-Labeled Compounds Parasite Drug Metabolite	Infection
Cycloguanil-d6 hydrochloride is the deuterium labeled Cycloguanil hydrochloride. Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes .

HY-12784AS

Cycloguanil-d4 hydrochloride	Parasite Drug Metabolite	Infection
Cycloguanil-d₄ (hydrochloride) is the deuterium labeled Cycloguanil hydrochloride. Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes[1].

HY-12784S1

Cycloguanil-d6(nitrate) Chlorguanide triazine-d₆ Nitrate	Isotope-Labeled Compounds Antifolate	Infection
Cycloguanil-d₆ (nitrate) is the deuterium labeled Cycloguanil, which is a dihydrofolate reductase inhibitor.

HY-B0806AS

Proguanil-d4 hydrochloride	Isotope-Labeled Compounds Parasite Antifolate	Infection
Proguanil-d₄ (hydrochloride) is the deuterium labeled Proguanil hydrochloride. Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor[1][2].

HY-B0806S1

Proguanil-d4	Antifolate Parasite	Infection
Proguanil-d₄ is the deuterium labeled Proguanil[1]. Proguanil, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil is a dihydrofolate reductase (DHFR) inhibitor[2][3].

HY-B0806R

Proguanil (Standard)	Parasite Antifolate	Infection
Proguanil (Standard) is the analytical standard of Proguanil. This product is intended for research and analytical applications. Proguanil, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil is a dihydrofolate reductase (DHFR) inhibitor .

HY-B0806AS1

Proguanil-d6 hydrochloride	Isotope-Labeled Compounds Parasite Antifolate	Infection
Proguanil-d₆ hydrochloride is the deuterium labeled Proguanil hydrochloride (HY-B0806A). Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor .

HY-P0031

Cyclo(RADfK) 1 Publications Verification	Integrin	Others
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis.

HY-101402

Cyclo(his-pro) Cyclo(histidyl-proline); Histidylproline diketopiperazine	NF-κB Endogenous Metabolite	Neurological Disease Inflammation/Immunology
Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .

HY-P0023

Cyclo(-RGDfK) Maximum Cited Publications 14 Publications Verification	Integrin	Cancer
Cyclo(-RGDfK) is a potent and selective inhibitor of the α_vβ₃ integrin, with an IC₅₀ of 0.94 nM . Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface .

HY-P0231

AZP-531 2 Publications Verification	GHSR	Metabolic Disease Endocrinology
AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.

HY-P1934

Cyclo(Phe-Pro) 4 Publications Verification Cyclo(phenylalanylprolyl); A-64863	HCV	Infection
Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)), a Vibrio vulnificus quorum-sensing molecule, inhibits retinoic acid-inducible gene-I (RIG-I) polyubiquitination, through its specific interaction with RIG-I, to blunt IRF-3 activation and type-I IFN production. Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) enhances susceptibility to hepatitis C virus (HCV), as well as Sendai and influenza viruses .

HY-126810A

NP213 TFA	Fungal	Infection
NP213 TFA is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has anti-fungal activities. NP213 TFA targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 TFA is effective and well-tolerated in resolving nail fungal infections .

HY-P0023A

Cyclo(-RGDfK) TFA Maximum Cited Publications 14 Publications Verification	Integrin	Cancer
Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the α_vβ₃ integrin, with an IC₅₀ of 0.94 nM . Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface .

HY-126810

NP213	Fungal	Infection
NP213 is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has anti-fungal activities. NP213 targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 is effective and well-tolerated in resolving nail fungal infections .

HY-107245

Segetalin B 1 Publications Verification	Estrogen Receptor/ERR	Metabolic Disease
Segetalin B, a cyclopentapeptide from Vaccaria segetalis, possesses estrogen-like activity .

HY-P1934A

Cyclo(L-Phe-L-Pro)	Fungal IFNAR Reactive Oxygen Species	Infection Inflammation/Immunology Cancer
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-P2300

Cyclo(Arg-Gly-Asp-D-Phe-Cys) Cyclo(RGDfC)	Integrin	Cancer
Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors .

HY-P1938

Cyclo(L-Pro-L-Val)	Bacterial	Infection
Cyclo(L-Pro-L-Val) is a 2,5-diketopiperazine, with toxic activity against phytopathogenic microorganisms (such as R. fascians LMG 3605). Cyclo(L-Pro-L-Val) shows toxicity similar to Chloramphenicol (HY-B0239) with comparable concentration. Cyclo(L-Pro-L-Val) can also inhibit gram-positive phytopathogenic bacterium. Cyclo(L-Pro-L-Val) has potential development as biopesticide .

HY-P5033

Cyclo(Gly-His)	Bacterial	Cancer
Cyclo(Gly-His) is a liposome-encapsulated cyclic dipeptide with antimicrobial and anticancer activity. Cyclo(Gly-His) has cytotoxicity for HeLa and MCF-7 cell with IC₅₀ values of 1.699 mM and 0.358 mM, respectively. Cyclo(Gly-His) can be used for the research of drug delivery systems .

HY-P5314

OK2	EGFR STAT	Others
OK2, a specific inhibitor of the CCN2/EGFR interaction, efficiently blocks CCN2/EGFR interaction through binding to the CT domain of CCN2. OK2 can be used for kidney fibrosis and chronic kidney disease research .

HY-P1935

Cyclo(Ala-Pro)	Biochemical Assay Reagents	Cancer
Cyclo(Ala-Pro) is an anticancer agent that is toxic to cancer cells such as A549, HCT-116 and HepG2 .

HY-P5038

Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) c(GRGDSP)	Integrin	Cancer
Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide. Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) is a synthetic α5β1 integrin ligand that competitively inhibits the binding of invasin (Inv) to α5β1 integrin expressed on Caco-2 cells .

HY-P5698

Cyclopetide 1	Bacterial	Infection
Cyclopetide 1 (Compound 1) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 25 μg/mL .

HY-P5699

Cyclopetide 2	Bacterial	Infection
Cyclopetide 2 (Compound 2) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 50 μg/mL .

HY-P10052

CBO-P11	VEGFR	Cancer
CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is modified with a nearinfrared cyanine dye bearing an alkyne function, allowing both “click” coupling on azido-modified nanoparticles and fluorescence labelling .

HY-P10222

Cyclo(CRLLIF)	HIF/HIF Prolyl-Hydroxylase	Cancer
Cyclo CRLLIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2, which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β, with affinity for HIF1-α and HIF2-α PAS-B domains K_D of 14.5 and 10.2 μM, respectively .

HY-P10223

Cyclo(CRVIIF)	HIF/HIF Prolyl-Hydroxylase	Cancer
Cyclo CRVIIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2, which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β, with affinity for HIF1-α and HIF2-α PAS-B domains K_D of 65 and 123 μM, respectively .

HY-P10221A

Cyclo(CKLIIF) TFA	HIF/HIF Prolyl-Hydroxylase	Cancer
Cyclo CKLIIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2, which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β, with affinity for HIF1-α and HIF2-α PAS-B domains K_D of 2.6 and 2.2 μM, respectively .

HY-P3119

Desotamide Desotamide A	Bacterial	Infection
Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs=16, 12.5, and 32 μg/mL, respectively).

HY-139425

Cyclo(Pro-Ala)	Biochemical Assay Reagents	Cancer
Cyclo(Pro-Ala) is an anticancer agent that has toxic to cancer cells such as A549, HCT-116, and HepG2 .

HY-P10426

cyclo(CLLFVY)	HIF/HIF Prolyl-Hydroxylase VEGFR	Cancer
cyclo(CLLFVY) is an inhibitor for hypoxia inducible factor-1 (HIF-1), with IC₅₀ of 19 μM (in U2OS) and 16 μM (in MCF-7). cyclo(CLLFVY) binds to the PAS-B domain of HIF-1α, inhibits HIF-1 dimerization and transcriptional activity. cyclo(CLLFVY) downregulates the expression of hypoxia response genes, such as VEGF and CAIX, exhibits antitumor against the HIF-1 associated cancers .

HY-P6294

Pseudostellarin G	Tyrosinase	Others
Pseudostellarin G is a natural cyclic octapeptide. Pseudostellarin G has the activity of inhibiting tyrosinase. Pseudostellarin G can inhibit the production of melanin .

HY-N11955

Cyclo(Ile-Leu)	Others	Others
Cyclo(Ile-Leu) is a Alkaloids product that can be isolated from From Penicillium oxalicum .

HY-P4820A

*SYNV-cyclo(CGGYF) TFA*	Bacterial	Inflammation/Immunology
SYNV-cyclo(CGGYF) TFA is a Staphylococcus hominis (S. hominis) C5 autoinducing peptide. SYNV-cyclo(CGGYF) TFA inhibits S. aureus activity. SYNV-cyclo(CGGYF) TFA has the potential for the research of S. aureus-mediated epithelial damage and inflammation .

HY-P4820

*SYNV-cyclo(CGGYF)*	Bacterial	Inflammation/Immunology
SYNV-cyclo(CGGYF) is a Staphylococcus hominis (S. hominis) C5 autoinducing peptide. SYNV-cyclo(CGGYF) inhibits S. aureus activity. SYNV-cyclo(CGGYF) has the potential for the research of S. aureus-mediated epithelial damage and inflammation .

HY-P3227

Cyclo(Ala-Arg-Gly-Asp-Mamb) XJ735	Integrin	Inflammation/Immunology
Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective RGD peptide antagonist and has the potential for Pulmonary arterial hypertension Research .

HY-P5712

Gramicidin S Gramicidin soviet	Antibiotic Bacterial	Infection
Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic. Gramicidin S is active against Gram-negative and Gram-positive bacteria by perturbing integrity of the bacterial membranes. Gramicidin S also inhibits cytochrome bd quinol oxidase .

HY-P1201

Cyclosomatostatin	Somatostatin Receptor	Cancer
Cyclosomatostatin is a potent somatostatin (SST) receptor antagonist. Cyclosomatostatin can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size and sphere-formation in colorectal cancer (CRC) cells .

HY-P1201A

Cyclosomatostatin TFA	Somatostatin Receptor	Cancer
Cyclosomatostatin TFA is a potent somatostatin (SST) receptor antagonist. Cyclosomatostatin TFA can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size and sphere-formation in colorectal cancer (CRC) cells .

HY-149205

CXJ-2	PI3K ERK	Inflammation/Immunology
CXJ-2 is a cyclic peptide, and exhibits moderate affinity toward elastin derived peptides (EDPs). CXJ-2 exhibits potent activities to inhibit the PI3K/ERK pathway and decrease hepatic stellate cell proliferation and migration. CXJ-2 possesses potent antifibrotic efficacy .

HY-P5840

Cyclo(RGDyC)	Biochemical Assay Reagents	Cancer
Cyclo(RGDyC) is a cyclic pentapeptide with anti-angiogenic abilities. Cyclo(RGDyC) can be combined with liposome delivery systems for research on ocular neovascular diseases and cancer .

HY-P1613A

Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA Cyclo(RGDfV) TFA; C(RGDfV) TFA	Integrin Apoptosis	Cancer
Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) (Cyclo(RGDfV) (TFA))is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) can be used for the research of acute myeloid leukemia .

HY-P1613

Cyclo(Arg-Gly-Asp-D-Phe-Val) Cyclo(RGDfV); C(RGDfV)	Integrin Apoptosis	Cancer
Cyclo(Arg-Gly-Asp-D-Phe-Val) (Cyclo(RGDfV)) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) can be used for the research of acute myeloid leukemia .

HY-P3557

Mibenratide	Adrenergic Receptor	Cardiovascular Disease
Mibenratide, a small cyclic peptide, is an adrenergic β1 receptor antagonist. Mibenratide can be used for heart failure research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-107245

Segetalin B 1 Publications Verification	Vaccaria segetalis (Neck.) Garcke Classification of Application Fields Cyclopeptides Source classification Metabolic Disease Plants Disease Research Fields Caryophyllaceae	Estrogen Receptor/ERR
Segetalin B, a cyclopentapeptide from Vaccaria segetalis, possesses estrogen-like activity .

HY-P1934A

Cyclo(L-Phe-L-Pro)	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields Cancer	Fungal IFNAR Reactive Oxygen Species
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC₅₀ of 24 µM in the DPPH assay .

HY-P1938

Cyclo(L-Pro-L-Val)	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Cyclo(L-Pro-L-Val) is a 2,5-diketopiperazine, with toxic activity against phytopathogenic microorganisms (such as R. fascians LMG 3605). Cyclo(L-Pro-L-Val) shows toxicity similar to Chloramphenicol (HY-B0239) with comparable concentration. Cyclo(L-Pro-L-Val) can also inhibit gram-positive phytopathogenic bacterium. Cyclo(L-Pro-L-Val) has potential development as biopesticide .

HY-101402

Cyclo(his-pro) Cyclo(histidyl-proline); Histidylproline diketopiperazine	Structural Classification Natural Products Source classification Endogenous metabolite	NF-κB Endogenous Metabolite
Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone . Cyclo(his-pro) could inhibit NF-κB nuclear accumulation. Cyclo(his-pro) can cross the brain-blood-barrier and affect diverse inflammatory and stress responses .

HY-P1935

Cyclo(Ala-Pro)	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Biochemical Assay Reagents
Cyclo(Ala-Pro) is an anticancer agent that is toxic to cancer cells such as A549, HCT-116 and HepG2 .

HY-P5698

Cyclopetide 1	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Cyclopetide 1 (Compound 1) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 25 μg/mL .

HY-P5699

Cyclopetide 2	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	Bacterial
Cyclopetide 2 (Compound 2) is an antimicrobial peptide with moderate activity against B. subtilis, with a MIC of 50 μg/mL .

HY-P6293

Heterophyllin A	Structural Classification Natural Products Pseudostellaria heterophylla (Miq.) Pax Source classification Plants Caryophyllaceae	Others
Heterophyllin A can be isolated from the aboveground parts of Elaeagnus angustifolia.

HY-N13127

Segetalin C	Structural Classification Natural Products Source classification Plants Vaccaria hispanica Caryophyllaceae	Others
Segetalin C is a cyclic peptide that increases uterine weight in ovariectomized rats (2.5 mg/kg).

HY-P6294

Pseudostellarin G	Structural Classification Natural Products Pseudostellaria heterophylla (Miq.) Pax Source classification Plants Caryophyllaceae	Tyrosinase
Pseudostellarin G is a natural cyclic octapeptide. Pseudostellarin G has the activity of inhibiting tyrosinase. Pseudostellarin G can inhibit the production of melanin .

HY-P1936

Cyclo(Gly-L-Pro)	Structural Classification Alkaloids Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Source classification Plants Araliaceae	Others
Cyclo(Gly-L-Pro) is a Alkaloids product that can be isolated from the roots of Panax notoginseng (Burk.)F.H.Chen .

HY-P5751

Cyclo(Ile-Val)	Structural Classification Alkaloids Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Other Alkaloids Source classification Plants Araliaceae	Others
Cyclo(Ile-Val) is a Alkaloids product that can be isolated from the roots of Panax notoginseng (Burk.)F.H.Chen .

HY-N11955

Cyclo(Ile-Leu)	Structural Classification Alkaloids Microorganisms Other Alkaloids Marine natural products Source classification Endogenous metabolite	Others
Cyclo(Ile-Leu) is a Alkaloids product that can be isolated from From Penicillium oxalicum .

HY-P1680

Astin C Asterin	Structural Classification Natural Products Source classification Plants Compositae Erythrina latissima E. Mey.	Others
Astin C (Asterin) is a cyclic pentapeptide with anticancer and anti-inflammatory properties .

HY-P2040

Nodularin	Structural Classification other families Cyclopeptides Ketones, Aldehydes, Acids Marine natural products Source classification Plants	Others
Nodularin is a potent hepatotoxin, tumor promoter, and protein phosphatase inhibitor .

HY-W019721

Cyclosporin D	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Nuclear Factor of activated T Cells (NFAT)
Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .

HY-P2005

Malformin C	Structural Classification Natural Products Microorganisms Source classification	Others
Malformin C is an algicidal peptide can be isolated from Aspergillus and exhibits dose-dependent algicidal activity. Malformin C induces a significant increase in ROS levels in algal cells, resulting in impaired SOD activity and high production of MDA content .

HY-P5957

Omphalotin A	Structural Classification Microorganisms Cyclopeptides Source classification	Parasite
Omphalotin A is a cyclic peptide, and shows nematicidal activity .

Cat. No.	Product Name	Chemical Structure