Search Result
Results for "
broad-spectrum antibacterial
" in MedChemExpress (MCE) Product Catalog:
4
Biochemical Assay Reagents
9
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-B2072A
-
|
Antibiotic
Bacterial
|
Infection
|
Cephaloridine hydrate is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity .
|
-
-
- HY-B0159
-
Q-35
|
Bacterial
Antibiotic
|
Infection
|
Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections .
|
-
-
- HY-16980A
-
TP-434 dihydrochloride; TP-434-046
|
Beta-lactamase
Bacterial
|
Infection
|
Eravacycline dihydrochloride (TP-434 dihydrochloride) is a potent and broad-spectrum antibacterial agent.
|
-
-
- HY-B2072
-
|
Antibiotic
Bacterial
|
Infection
|
Cephaloridine is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity .
|
-
-
- HY-B1354
-
SM-1652 free acid; Wy-44635 free acid
|
Beta-lactamase
Antibiotic
Bacterial
|
Infection
|
Cefpiramide (SM-1652) free acid is a semisynthetic cephalosporin with broad-spectrum antibacterial activity. Cefpiramide free acid shows strong antibacterial effect on both gram-positive bacteria and gram-negative bacteria. Cefpiramide free acid is moderately susceptible to β-lactamase .
|
-
-
- HY-14762
-
|
Antibiotic
Bacterial
|
Infection
|
Besifloxacin is a fluoroquinolone antimicrobial agent. Besifloxacin can inhibit cytokine production by monocytes. Besifloxacin has broad-spectrum antibacterial activity .
|
-
-
- HY-16980
-
-
-
- HY-B0159A
-
Q-35 dihydrate
|
Bacterial
Antibiotic
|
Infection
|
Balofloxacin dihydrate (Q-35 dihydrate) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin dihydrate can be used for the research of respiratory, intestinal, and urinary tract infections .
|
-
-
- HY-105113
-
-
-
- HY-119280
-
-
-
- HY-B0159R
-
|
Bacterial
Antibiotic
|
Infection
|
Balofloxacin (Standard) is the analytical standard of Balofloxacin. This product is intended for research and analytical applications. Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections .
|
-
-
- HY-106339
-
-
-
- HY-N7115
-
|
Bacterial
Antibiotic
|
Infection
|
Sultamicillin is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .
|
-
-
- HY-N7111
-
Sultamicillin (tosilate)
|
Bacterial
Antibiotic
|
Infection
|
Sultamicillin tosylate is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .
|
-
-
- HY-132282
-
|
Bacterial
|
Infection
|
Thiamphenicol glycinate hydrochloride is a broad-spectrum antibacterial agent that can be used for respiratory tract infections research .
|
-
-
- HY-B1414
-
-
-
- HY-W588257
-
-
-
- HY-B1366
-
|
Bacterial
Antibiotic
|
Infection
|
Meclocycline Sulfosalicylate Salt is a tetracycline antibiotic with broad-spectrum antibacterial activities, preventing skin bacterial infections such as acne vulgaris .
|
-
-
- HY-156005
-
|
Bacterial
|
Others
|
Antibacterial agent 153 is a broad-spectrum antibacterial agent. Antibacterial agent 153 kills bacteria by acting on the bacterial cell membrane. Antibacterial agent 153 can be used for bacterial infections research .
|
-
-
- HY-B1374
-
-
-
- HY-135393S
-
|
Isotope-Labeled Compounds
Bacterial
|
Infection
|
Sulfadimethoxypyrimidine-d4 is a deuterium labeled Sulfadimethoxypyrimidine. Sulfadimethoxypyrimidine is a sulfonamide antibiotic with a broad-spectrum antibacterial effect[1].
|
-
-
- HY-B1825
-
|
Antibiotic
Bacterial
|
Infection
Cancer
|
Cefoxitin, a β-lactam antibiotic, is a broad-spectrum, second-generation cephalosporin. Cefoxitin has a broad spectrum antibacterial activity which includes anaerobic as well as Gram-positive and Gram-negative aerobic bacteria .
|
-
-
- HY-123451
-
|
Bacterial
|
Infection
|
ACH-702 is a potent anti-tubercular agent. ACH-702 also shows broad-spectrum antibacterial activity .
|
-
-
- HY-16487
-
TMFX; TA-167 free acid; A-62254 free acid
|
Bacterial
Antibiotic
|
Infection
|
Temafloxacin (TMFX) is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin is well tolerated in lower respiratory and genitourinary tract infections .
|
-
-
- HY-113595
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TMFX hydrochloride; TA-167; A-62254
|
Antibiotic
Bacterial
|
Infection
|
Temafloxacin (TMFX) hydrochloride is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin hydrochloride is well tolerated in lower respiratory and genitourinary tract infections .
|
-
-
- HY-108279
-
|
Antibiotic
Bacterial
|
Infection
|
Ulifloxacin is a broad-spectrum quinolone antibiotic. Ulifloxacin is the active metabolite of Prulifloxacin (HY-B0024). Ulifloxacin has anti-bacterial activity .
|
-
-
- HY-123614
-
|
Bacterial
|
Infection
|
PD 140248 hydrochloride is a quinolone broad-spectrum antibacterial agent with good in vitro bacteriostatic activity, especially having a significant inhibitory effect on Gram-positive bacteria .
|
-
-
- HY-109754
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PF-03709270
|
Bacterial
Antibiotic
|
Infection
|
Sulopenem etzadroxil (PF-03709270) is an orally available ester proagent form of sulopenem, with broad-spectrum antibacterial activity against most gram-positive and gram-negative bacteria.
|
-
-
- HY-P2460
-
|
Bacterial
Fungal
|
Infection
Inflammation/Immunology
|
SMAP-29, a promising antiinfective agent, is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide. SMAP-29 acts by permeabilizing bacterial membranes and inducing remarkable changes in the surface morphology of susceptible microorganism .
|
-
-
- HY-B1444
-
|
Bacterial
Fungal
Antibiotic
|
Infection
|
Isoconazole nitrate is a broad-spectrum antimicrobial agent with a highly effective antimycotic and gram-positive antibacterial activity, exhibiting a rapid rate of absorption and low systemic exposure potential .
|
-
-
- HY-N7066
-
|
Bacterial
Antibiotic
|
Infection
|
Difloxacin hydrochloride is a broad-spectrum antibacterial agent. Difloxacin hydrochloride inhibits bacterial DNA gyrase and exhibits a concentration-dependant bactericidal effect by interference with the activity of DNA gyrase and topoisomerase IV .
|
-
-
- HY-N7449
-
-
-
- HY-B0529
-
|
Bacterial
Parasite
Antibiotic
|
Infection
|
Azlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection .
|
-
-
- HY-N7115R
-
|
Bacterial
Antibiotic
|
Infection
|
Sultamicillin (Standard) is the analytical standard of Sultamicillin. This product is intended for research and analytical applications. Sultamicillin is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .
|
-
-
- HY-N7111R
-
|
Bacterial
Antibiotic
|
Infection
|
Sultamicillin (tosylate) (Standard) is the analytical standard of Sultamicillin (tosylate). This product is intended for research and analytical applications. Sultamicillin tosylate is a broad-spectrum and orally active beta-lactamase inhibitor, an antibiotic with antibacterial activity .
|
-
-
- HY-B1825R
-
|
Antibiotic
Bacterial
|
Infection
Cancer
|
Cefoxitin (Standard) is the analytical standard of Cefoxitin. This product is intended for research and analytical applications. Cefoxitin, a β-lactam antibiotic, is a broad-spectrum, second-generation cephalosporin. Cefoxitin has a broad spectrum antibacterial activity which includes anaerobic as well as Gram-positive and Gram-negative aerobic bacteria .
|
-
-
- HY-N0565A
-
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity .
|
-
-
- HY-N0565
-
Doxycycline
Maximum Cited Publications
88 Publications Verification
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline shows antibacterial activity and anti-cancer cell proliferation activity .
|
-
-
- HY-B1414R
-
|
Bacterial
Influenza Virus
Parasite
|
Infection
|
Chloroxylenol (Standard) is the analytical standard of Chloroxylenol. This product is intended for research and analytical applications. Chloroxylenol is a broad-spectrum antibacterial agent that can be used to control bacteria, algae, fungi and viruses .
|
-
-
- HY-105393
-
Antibiotic LB 10517 sodium
|
Bacterial
|
Infection
|
LB 10517 (sodium) is a type of cephalosporin. LB 10517 (sodium) has broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria, including Enterobacteriaceae, Pseudomonas aeruginosa, Staphylococcus, and Streptococcus .
|
-
-
- HY-W740165
-
|
Antibiotic
Drug Metabolite
|
Infection
|
Desmethyl Levofloxacin hydrochloride is an antibacterial agent with broad-spectrum antibacterial activity against a variety of pathogens. Desmethyl Levofloxacin hydrochloride effectively fights bacterial infections by inhibiting bacterial DNA synthesis. Studies on Desmethyl Levofloxacin hydrochloride have shown that it has potential in inhibiting respiratory infections .
|
-
-
- HY-N0565B
-
Doxycycline hydrochloride hemiethanolate hemihydrate; WC2031
|
Antibiotic
MMP
Bacterial
Parasite
|
Infection
Cancer
|
Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity .
|
-
-
- HY-115349
-
|
Antibiotic
Bacterial
|
Infection
Neurological Disease
Cancer
|
Neamine tetrahydrochloride, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine tetrahydrochloride is an anti-angiogenesis agent targeting angiogenin. Neamine tetrahydrochloride has potent antibacterial, antitumor and neuroprotective activities .
|
-
-
- HY-N0565C
-
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
Doxycycline calcium, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline calcium shows antibacterial activity and anti-cancer cell proliferation activity .
|
-
-
- HY-P5691
-
|
Bacterial
|
Infection
|
P1 is a broad-spectrum antimicrobial peptide. P1 shows antibacterial activity against Gram-positive and Gram-negative bacteria,such as B. anthracis spores and Carbapenem-resistant A. baumannii and K. pneumoniae .
|
-
-
- HY-B1374R
-
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
|
Florfenicol (Standard) is the analytical standard of Florfenicol. This product is intended for research and analytical applications. Florfenicol ((-)-Florfenicol) is an orally active broad-spectrum antibacterial antibiotic with anti-inflammatory, pro apoptotic, and immunomodulatory functions .
|
-
-
- HY-W018025
-
-
-
- HY-P5561
-
|
Antibiotic
Bacterial
|
Infection
|
Aurein 2.2 is a major component of the skin secretion of L.aurea. Aurein 2.2 is an antibiotic with broad-spectrum antibacterial activity against Gram positive bacteria such as Staphylococcus aureus and S. epidermidis .
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-
-
- HY-B1366R
-
|
Bacterial
Antibiotic
|
Infection
|
Meclocycline (Sulfosalicylate Salt) (Standard) is the analytical standard of Meclocycline (Sulfosalicylate Salt). This product is intended for research and analytical applications. Meclocycline Sulfosalicylate Salt is a tetracycline antibiotic with broad-spectrum antibacterial activities, preventing skin bacterial infections such as acne vulgaris .
|
-
-
- HY-16468
-
MSI-1256
|
Bacterial
HBV
FAK
Dengue virus
|
Infection
Neurological Disease
Cancer
|
Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson ,s disease mouse models .
|
-
- HY-16487R
-
|
Bacterial
Antibiotic
|
Infection
|
Temafloxacin (Standard) is the analytical standard of Temafloxacin. This product is intended for research and analytical applications. Temafloxacin (TMFX) is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin is well tolerated in lower respiratory and genitourinary tract infections .
|
-
- HY-108279R
-
|
Antibiotic
Bacterial
|
Infection
|
Ulifloxacin (Standard) is the analytical standard of Ulifloxacin. This product is intended for research and analytical applications. Ulifloxacin is a broad-spectrum quinolone antibiotic. Ulifloxacin is the active metabolite of Prulifloxacin (HY-B0024). Ulifloxacin has anti-bacterial activity .
|
-
- HY-B0692
-
-
- HY-B0692A
-
BMY-28142 chloride
|
Penicillin-binding protein (PBP)
Antibiotic
Bacterial
|
Infection
|
Cefepime (BMY-28142) chloride is a broad-spectrum and cross the blood-brain barrier cephalosporin. Cefepime chloride shows antibacterial effects against both Gram-positive and Gram-negative aerobic bacteria. Cefepime chloride induces neurotoxicity .
|
-
- HY-155546
-
|
Bacterial
|
Infection
|
Antimicrobial agent-22 (THI 6c) is a multi-target broad-spectrum antibacterial agent. Antimicrobial agent-22 has low cytotoxicity, hemolytic property, rapid bactericidal ability and good anti-biofilm activity .
|
-
- HY-P10431
-
Sea snake cathelicidin
|
Bacterial
|
Infection
Inflammation/Immunology
|
Hc-CATH (Sea snake cathelicidin) is an antibacterial peptide with broad-spectrum. Hc-CATH inhibits Shigella dysenteriae and Klebsiella pneumoniae with MIC of 0.16 mM-20.67 mM. Hc-CATH exhibits anti-inflammatory efficacy .
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-
- HY-143408
-
|
Bacterial
|
Infection
|
OYYF-175, an antimicrobial antifolate, is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 2.36 nM for Escherichia coli DHFR. OYYF-175 exhibits potent broad-spectrum antibacterial activities, especially against multi-drug resistant Gram-Negative-strains .
|
-
- HY-118547
-
2-Benzyl-4-chlorophenol
|
Bacterial
|
Infection
|
Clorofene (2-Benzyl-4-chlorophenol) is an aryl halide fungicide widely used in hospitals and homes as a broad-spectrum fungicide in general cleaning and disinfection disinfectant solutions and in soap formulations. Clorofene has antibacterial and carcinogenic activity .
|
-
- HY-N7066R
-
|
Bacterial
Antibiotic
|
Infection
|
Difloxacin (hydrochloride) (Standard) is the analytical standard of Difloxacin (hydrochloride). This product is intended for research and analytical applications. Difloxacin hydrochloride is a broad-spectrum antibacterial agent. Difloxacin hydrochloride inhibits bacterial DNA gyrase and exhibits a concentration-dependant bactericidal effect by interference with the activity of DNA gyrase and topoisomerase IV .
|
-
- HY-W140760
-
|
Others
|
Infection
Inflammation/Immunology
Cancer
|
Ceftriaxone sodium is a versatile broad-spectrum β-lactam tertiary cephalosporin antibiotic that exhibits anti-inflammatory, antitumor, antibacterial, and antioxidant properties, and functions as a covalent inhibitor of GSK3β and Aurora B, making it valuable in research related to sepsis and infective endocarditis.
|
-
- HY-N13140
-
|
Antibiotic
Bacterial
|
Infection
|
vDifficidin is an antibiotic, that can be produced by Bacillus velezensis. Difficidin exhibits broad-spectrum antibacterial activity through suppression of protein biosynthesis. Difficidin is potent in controlling plant pathogens, such as Erwinia amylovora (orchard fire blight pathogen) and Xanthomonas oryzae (rice disease pathogen) .
|
-
- HY-B0529R
-
|
Bacterial
Parasite
Antibiotic
|
Infection
|
Azlocillin (Standard) is the analytical standard of Azlocillin. This product is intended for research and analytical applications. Azlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection .
|
-
- HY-P5724
-
|
Bacterial
|
Infection
|
Nv-CATH is an antibacterial peptide of frog origin. Nv-CATH has broad-spectrum antibacterial activity against gram-positive and gram-negative bacteria. Nv-CATH significantly protects mice from fatal infections caused by Staphylococcus aureus. Nv-CATH protects mice from bacterial infection through antimicrobial immunoregulatory duality .
|
-
- HY-B1464
-
|
Bacterial
HBV
|
Infection
Inflammation/Immunology
|
Cetylpyridinium chloride, a cationic quaternary ammonium compound, is an anti-bacterial agent with broad-spectrum activity. Cetylpyridinium chloride is an effective anti-HBV capsid assembly inhibitor with an IC50 of 2.5 μM. Cetylpyridinium chloride is used in pesticides and various types of mouthwashes, and other personal care products .
|
-
- HY-B1444R
-
|
Bacterial
Fungal
Antibiotic
|
Infection
|
Isoconazole (nitrate) (Standard) is the analytical standard of Isoconazole (nitrate). This product is intended for research and analytical applications. Isoconazole nitrate is a broad-spectrum antimicrobial agent with a highly effective antimycotic and gram-positive antibacterial activity, exhibiting a rapid rate of absorption and low systemic exposure potential .
|
-
- HY-W392026
-
PHMGH
|
Antibiotic
Bacterial
Fungal
|
Infection
|
Polyhexamethyleneguanidine (PHMGH) hydrochloride is a positively charged polymer with broad-spectrum antimicrobial activity. It exerts its antibacterial effects by binding to the cell membranes of bacteria and fungi, disrupting membrane integrity. Polyhexamethyleneguanidine hydrochloride can be applied in studies related to disinfection, water treatment, pesticides, and other fields [2]
|
-
- HY-N0565AR
-
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
Doxycycline (hydrochloride) (Standard) is the analytical standard of Doxycycline (hydrochloride). This product is intended for research and analytical applications. Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity [4] .
|
-
- HY-N0565R
-
|
MMP
Bacterial
Antibiotic
Parasite
|
Infection
Cancer
|
Doxycycline (Standard) is the analytical standard of Doxycycline. This product is intended for research and analytical applications. Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline shows antibacterial activity and anti-cancer cell proliferation activity [4] .
|
-
- HY-159809
-
|
Others
|
Infection
Inflammation/Immunology
|
Antibacterial agent 249 demonstrates broad-spectrum antimicrobial properties, effectively inhibiting the growth of Aspergillus niger, Bacillus subtilis, Pseudomonas albicans, Escherichia coli, and Staphylococcus aureus, while also exhibiting anti-inflammatory activity in vitro, making it a potential candidate for treating bacterial infections.
|
-
- HY-P10228
-
|
Fungal
Bacterial
|
Infection
|
S-Thanatin is an insect antimicrobial peptide with potent broad-spectrum antibacterial activity. S-Thanatin can inhibit the activity of Gram-negative bacteria, Gram-positive bacteria, and fungi, without cytotoxicity. The antibacterial activity of S-Thanatin is not affected by PH value, but monovalent cations (Na +/K +) can reduce its antibacterial activity against Gram-negative bacteria in a dose-dependent manner .
|
-
- HY-N7112
-
Kitasamycin
|
Bacterial
Antibiotic
|
Infection
|
Leucomycin (Kitasamycin) is an orally active macrolide antibiotic produced by Streptomyces kitasatoensis. Leucomycin has broad-spectrum antibacterial activities against gram-positive and gram-negative bacteria, mycoplasma, leptospira, spirochaetes, rickettsiae and some larger viruses .
|
-
- HY-162782A
-
|
Antibiotic
Bacterial
|
Infection
|
V–C6–Bg-PhCl TFA (compound 5e) is a biguanide-vancomycin conjugate. V–C6–Bg-PhCl TFA has broad-spectrum antibacterial activity against both Gram-negative and Gram-positive bacteria .
|
-
- HY-B0210
-
-
- HY-137139
-
|
Antibiotic
Bacterial
Farnesyl Transferase
|
Infection
Cancer
|
10'-Desmethoxystreptonigrin is an inhibitor for Ras Farnesyltransferase with an IC50 of 21 μM. 10'-Desmethoxystreptonigrin is a broad-spectrum antibiotic with antibacterial activity. 10'-Desmethoxystreptonigrin exhibits antitumor activity against P388 leukemia, without significant cytotoxicity (LD50 is 8.8 mg/kg) .
|
-
- HY-14926A
-
(S)-(-)-Nadifloxacin (arginine) hydrate; WCK-771A (arginine) hydrate
|
Antibiotic
Bacterial
|
Infection
|
Levonadifloxacin (arginine) hydrate is a broad-spectrum anti-staphylococcal agent. Levonadifloxacin (arginine) hydrate shows antibacterial activity against Methicillin (HY-121544)-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) strains, with a reduction of which phagocytized in THP-1 monocytes .
|
-
- HY-B0210C
-
-
- HY-A0208
-
Acrosoxacin
|
Bacterial
Antibiotic
|
Infection
|
Rosoxacin (Acrosoxacin) is an orally active and broad-spectrum antibacterial quinolone antibiotic. Rosoxacin inhibits Gram-negative bacteria, including N. gonorrhoeae (MIC range=0.03-0.125 µg/mL).Rosoxacin can be used in studies of urinary tract infections and certain sexually transmitted diseases .
|
-
- HY-14926
-
(S)-(-)-Nadifloxacin; WCK 771
|
Antibiotic
Bacterial
|
Infection
|
Levonadifloxacin ((S)-(-)-Nadifloxacin; WCK 771) is a broad-spectrum anti-staphylococcal agent. Levonadifloxacin shows antibacterial activity against Methicillin (HY-121544)-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) strains, with a reduction of which phagocytized in THP-1 monocytes .
|
-
- HY-N0565BR
-
|
Antibiotic
MMP
Bacterial
Parasite
|
Infection
Cancer
|
Doxycycline hyclate (Standard) is the analytical standard of Doxycycline hyclate. This product is intended for research and analytical applications. Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity .
|
-
- HY-116519
-
|
Bacterial
|
Infection
|
LY173013 is an antibacterial agent with a broad spectrum antibacterial activity. LY173013 binds to PBP 3 of E.coli and can be utilized in antibacterial research .
|
-
- HY-W250302
-
|
Biochemical Assay Reagents
|
Others
|
Methylbenzethonium chloride is a quaternary ammonium compound commonly used as a preservative and disinfectant in a variety of personal care and healthcare products. Methylbenzethonium chloride has several properties that make it suitable for these applications, including its broad-spectrum antibacterial activity against bacteria, viruses and fungi. In addition, it is used as a preservative in cosmetic and pharmaceutical formulations to prevent the growth of microorganisms.
|
-
- HY-159688
-
|
Bacterial
|
Infection
|
Cefditoren is an orally active antibiotic with broad-spectrum antibacterial activity, capable of inhibiting both Gram-negative and Gram-positive bacteria. It has a MIC50 of 0.25-0.5 mg/L against Streptococcus pneumoniae strains. Cefditoren is effective against respiratory tract infections and skin infections .
|
-
- HY-13573
-
-
- HY-B0210A
-
CP 52640-2
|
Bacterial
Antibiotic
|
Infection
|
Cefoperazone sodium salt (CP 52640-2), a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .
|
-
- HY-162923
-
|
Bacterial
Antibiotic
|
Infection
|
Antibacterial agent 244 is an orally active compound with broad-spectrum antibacterial activity, primarily targeting Gram-positive bacteria, with a MIC value of 1–4 μg/mL and low hemolytic toxicity (HC50 of 111.6 μg/mL). Antibacterial agent 244 disrupts bacterial transmembrane potential, increases membrane permeability, leading to leakage of cellular contents such as DNA and proteins, ultimately causing bacterial death. Antibacterial agent 244 can be used in research related to Gram-positive bacterial infections .
|
-
- HY-B0608
-
|
Bacterial
Antibiotic
Apoptosis
Necroptosis
|
Infection
Cancer
|
Chlorhexidine digluconate is a chlorophenyl biguanide with broad antibacterial action against both Gram (+) and (-) bacteria and fungi. Chlorhexidine digluconate is a broad-spectrum antiseptic and disinfectant. Chlorhexidine digluconate is effective to prevent and control infectious diseases of the mouth by killing bacteria in saliva and tongue. Chlorhexidine digluconate is a cytotoxic agent and induces cell necrosis and apoptosis .
|
-
- HY-B0692R
-
|
Penicillin-binding protein (PBP)
Antibiotic
Bacterial
|
Infection
Cancer
|
Cefepime (Standard) is the analytical standard of Cefepime. This product is intended for research and analytical applications. Cefepime (BMY-28142) is a broad-spectrum and cross the blood-brain barrier cephalosporin. Cefepime shows antibacterial effects against both Gram-positive and Gram-negative aerobic bacteria. Cefepime induces neurotoxicity .
|
-
- HY-123319A
-
|
Bacterial
Antibiotic
|
Infection
|
Antofloxacin is a well tolerate, orally active and broad-spectrum 8-amino-fluoroquinolone with potent antibacterial activities. Antofloxacin shows superior antibacterial activity against gyrA mutation-positive H. pylori strains, especially in Asn87- mutated strains, compared to levofloxacin. Antofloxacin is a weak, reversible inhibitor of CYP1A2 for the research of infections caused by a diverse group of bacterial species .
|
-
- HY-123319
-
|
Bacterial
Antibiotic
|
Infection
|
Antofloxacin hydrochloride is a well tolerate, orally active and broad-spectrum 8-amino-fluoroquinolone with potent antibacterial activities. Antofloxacin hydrochloride shows superior antibacterial activity against gyrA mutation-positive H. pylori strains, especially in Asn87- mutated strains, compared to levofloxacin. Antofloxacin hydrochloride is a weak, reversible inhibitor of CYP1A2 for the research of infections caused by a diverse group of bacterial species .
|
-
- HY-130066
-
|
Antibiotic
Bacterial
|
Infection
|
Fortimicin C is an antibiotic, which can be isolated from Micromonospora olivoasterospora. Fortimicin C exhibits broad-spectrum antibacterial activity, inhibits Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumoniae, Salmonella typhosa and Serratia marcescens, with MICs of 0.16-0.64 μg/mL. Fortimicin C is resistant against aminoglycoside inactivating enzymes .
|
-
- HY-W018025R
-
|
Bacterial
Fungal
Parasite
Endogenous Metabolite
|
Infection
Inflammation/Immunology
|
5,6-Dihydroxyindole (Standard) is the analytical standard of 5,6-Dihydroxyindole. This product is intended for research and analytical applications. 5,6-Dihydroxyindole, a melanin precursor, has a broad-spectrum antibacterial, antifungal, antiviral, antiparasitic activity. 5,6-Dihydroxyindole has cytotoxic effects and is strongly toxic against various pathogens .
|
-
- HY-W740053
-
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
Cancer
|
Meropenem sodium is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem sodium has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
|
-
- HY-B1050
-
SB-265805S; LB-20304a
|
Bacterial
Antibiotic
DNA/RNA Synthesis
Topoisomerase
|
Infection
|
Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections .
|
-
- HY-B0798
-
SM-1652; Wy-44635
|
Bacterial
Antibiotic
|
Infection
|
Cefpiramide sodium (SM-1652; Wy-44635) is a new Pseudomonas-active cephalosporin with a broad spectrum of antibacterial activity.
|
-
- HY-N7125
-
|
Bacterial
|
Others
|
Cinnamyl acetate has a wide application in the flavor and fragrance industry . Cinnamyl acetate is a new broad spectrum antibacterial agent .
|
-
- HY-13678
-
SM 7338
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
Cancer
|
Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
|
-
- HY-B1257
-
Sodium cefmetazole
|
Bacterial
Antibiotic
|
Infection
|
Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
|
-
- HY-B1595
-
CS 1170
|
Antibiotic
Bacterial
|
Infection
|
Cefmetazole (CS 1170) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative and anaerobic bacteria. Cefmetazole binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
|
-
- HY-B0226A
-
(E)-Nitrofural
|
Bacterial
Parasite
|
Infection
|
(E)-Nitrofurazone ((E)-Nitrofural) is a topical broad-spectrum antibacterial agent effective against both Gram-negative and Gram-positive bacteria. (E)-Nitrofurazone also possesses antiprotozoal and antiparasitic activities. (E)-Nitrofurazone is commonly used in the research of superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, trypanosomiasis, and acute bacillary dysentery .
|
-
- HY-B1464R
-
|
Bacterial
HBV
|
Infection
Inflammation/Immunology
|
Cetylpyridinium (chloride) (Standard) is the analytical standard of Cetylpyridinium (chloride). This product is intended for research and analytical applications. Cetylpyridinium chloride, a cationic quaternary ammonium compound, is an anti-bacterial agent with broad-spectrum activity. Cetylpyridinium chloride is an effective anti-HBV capsid assembly inhibitor with an IC50 of 2.5 μM. Cetylpyridinium chloride is used in pesticides and various types of mouthwashes, and other personal care products .
|
-
- HY-16764A
-
JNJ-Q2 hydrochloride
|
Bacterial
|
Infection
Inflammation/Immunology
|
Acorafloxacin hydrochloride (JNJ-Q2 hydrochloride) is a broad-spectrum fluoroquinolone anti-bacterial drug being developed for the treatment of acute bacterial skin and skin-structure infections and community-acquired pneumonia .
Acorafloxacin hydrochloride (Avarofloxacin ) is an aminoethylidenylpiperidine fluoroquinolone that demonstrates antibacterial effect against numerous Gram-positive bacteria with a mean 0.12 mg/L MIC90 value .
Acorafloxacin hydrochloride (JNJ-Q2) has potential for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections .
|
-
- HY-13678A
-
SM 7338 trihydrate
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
Cancer
|
Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
|
-
- HY-N3139
-
|
Bacterial
|
Infection
|
Ombuin, isolated from Zanthoxylum armatum, displays broad spectrum antibacterial effect with MIC ranges from 125 to 500 μg/mL .
|
-
- HY-B0210S
-
-
- HY-10581A
-
AM-1155 hydrochloride; BMS-206584 hydrochloride; PD135432 hydrochloride
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml) . Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo.
|
-
- HY-10581B
-
AM-1155 mesylate; BMS-206584 mesylate; PD135432 mesylate
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
Gatifloxacin mesylate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin mesylate inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml) . Gatifloxacin mesylate can be used to treat bacterial conjunctivitis in vivo.
|
-
- HY-14865C
-
PTK0796 hydrochloride; Amadacycline hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
- HY-16764
-
JNJ-Q2
|
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial agent being developed for the treatment of acute bacterial skin and skin-structure infections and community-acquired pneumonia with oral activity. Avarofloxacin (JNJ-Q2) is an aminoethylidenylpiperidine fluoroquinolone that demonstrates antibacterial effect against numerous Gram-positive bacteria with a mean 0.12 mg/L MIC90 value. Avarofloxacin (JNJ-Q2) has potential for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections .
|
-
- HY-14865
-
PTK 0796; Amadacycline
|
Bacterial
Antibiotic
|
Infection
|
Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
- HY-14865A
-
PTK 0796 mesylate; Amadacycline mesylate
|
Bacterial
Antibiotic
|
Infection
|
Omadacycline (PTK 0796) mesylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline mesylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline mesylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline mesylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
- HY-14865B
-
PTK 0796 tosylate; Amadacycline tosylate
|
Bacterial
Antibiotic
|
Infection
|
Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
- HY-B1050R
-
|
Bacterial
Antibiotic
DNA/RNA Synthesis
Topoisomerase
|
Infection
|
Gemifloxacin (mesylate) (Standard) is the analytical standard of Gemifloxacin (mesylate). This product is intended for research and analytical applications. Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections .
|
-
- HY-B0210R
-
|
Bacterial
Antibiotic
|
Infection
|
Cefoperazone (Standard) is the analytical standard of Cefoperazone. This product is intended for research and analytical applications. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .
|
-
- HY-139618
-
|
Bacterial
Antibiotic
|
Infection
|
DuP-721 is a broad spectrum and orally active antibacterial agent against a variety of clinically susceptible and resistant bacteria, especially M. tuberculosis .
|
-
- HY-10581
-
AM-1155; BMS-206584; PD135432
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
Gatifloxacin (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50=0.109 μg/ml) . Gatifloxacin can be used to treat bacterial conjunctivitis in vivo.
|
-
- HY-10581C
-
AM-1155 sesquihydrate; BMS-206584 sesquihydrate; PD135432 sesquihydrate
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
Inflammation/Immunology
|
Gatifloxacin sesquihydrate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin sesquihydrate inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml) . Gatifloxacin sesquihydrate can be used to treat bacterial conjunctivitis in vivo.
|
-
- HY-17452
-
ME 1206
|
Beta-lactamase
Bacterial
|
Infection
Inflammation/Immunology
|
Cefditoren sodium (ME 1206) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren sodium has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren sodium can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .
|
-
- HY-16745A
-
KRP-AM1977 hydrochloride
|
Others
|
Infection
|
Lascufloxacin (KRP-AM1977) hydrochloride is a potent antibacterial compound candidate with broad-spectrum activity against various clinical isolates. Lascufloxacin hydrochloride shows the most potent activity against Gram-positive bacteria compared to other tested quinolones. Lascufloxacin hydrochloride demonstrates incomplete cross-resistance against existing quinolone-resistant strains. Lascufloxacin hydrochloride has potent inhibitory activity against both wild-type and mutated target enzymes.
|
-
- HY-13678S
-
SM 7338-d6
|
Bacterial
Antibiotic
|
Infection
|
Meropenem-d6 is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2].
|
-
- HY-146165
-
|
Beta-lactamase
Bacterial
|
Infection
|
Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity .
|
-
- HY-B0608R
-
|
Bacterial
Antibiotic
Apoptosis
Necroptosis
|
Infection
Cancer
|
Chlorhexidine (digluconate) (Standard) is the analytical standard of Chlorhexidine (digluconate). This product is intended for research and analytical applications. Chlorhexidine digluconate is a chlorophenyl biguanide with broad antibacterial action against both Gram (+) and (-) bacteria and fungi. Chlorhexidine digluconate is a broad-spectrum antiseptic and disinfectant. Chlorhexidine digluconate is effective to prevent and control infectious diseases of the mouth by killing bacteria in saliva and tongue. Chlorhexidine digluconate is a cytotoxic agent and induces cell necrosis and apoptosis .
|
-
- HY-117108
-
|
Antibiotic
Bacterial
|
Infection
|
Nocardicin A is a beta-lactam antibiotic with selective antibacterial activity. Nocardicin A has moderate antibacterial activity against a broad spectrum of Gram-negative bacteria including Proteus and Pseudomonas; it has no inhibitory effect on Staphylococcus, Mycobacterium, fungi, and yeast .
|
-
- HY-B1802B
-
A-61827 hydrochloride
|
Antibiotic
Bacterial
|
Infection
|
Tosufloxacin (A-61827) hydrochloride is an orally active fluoroquinolone antibiotic. Tosufloxacin hydrochloride shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-13573R
-
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
Biapenem (Standard) is the analytical standard of Biapenem. This product is intended for research and analytical applications. Biapenem (CLI 86815; L 627; LJC 10627) a parenteral carbapenem antibacterial agent with a broad spectrum.
|
-
- HY-B0210AR
-
|
Bacterial
Antibiotic
|
Infection
|
Cefoperazone (sodium salt) (Standard) is the analytical standard of Cefoperazone (sodium salt). This product is intended for research and analytical applications. Cefoperazone sodium salt (CP 52640-2), a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .
|
-
- HY-B1802A
-
A-61827 tosylate hydrate; T-3262
|
Bacterial
Antibiotic
|
Infection
|
Tosufloxacin tosylate hydrate (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-P3459
-
|
Bacterial
|
Infection
|
Tet-213 is a antimicrobial peptide. Tet-213 has broad spectrum antibacterial activity. Tet-213 can promote infected wound repair .
|
-
- HY-B1802
-
A-61827
|
Antibiotic
Bacterial
|
Infection
|
Tosufloxacin (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-B1802C
-
A-61827 tosylate
|
Antibiotic
Bacterial
|
Infection
|
Tosufloxacin (A-61827) tosylate is an orally active fluoroquinolone antibiotic. Tosufloxacin tosylate shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-W799435
-
A-61827 hydrate
|
Antibiotic
Bacterial
|
Infection
|
Tosufloxacin (A-61827) tosylate is an orally active fluoroquinolone antibiotic. Tosufloxacin tosylate shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-17452A
-
Cefditoren pivoxyl; Cefditoren pivaloyloxymethyl ester; ME 1207
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
Cefditoren Pivoxil (ME 1207) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .
|
-
- HY-10581AS
-
AM-1155-d3 hydrochloride; BMS-206584-d3 hydrochloride; PD135432-d3 hydrochloride
|
Isotope-Labeled Compounds
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
Gatifloxacin-d3 (hydrochloride) is the deuterium labeled Gatifloxacin (hydrochloride). Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo.
|
-
- HY-13678R
-
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
Cancer
|
Meropenem (Standard) is the analytical standard of Meropenem. This product is intended for research and analytical applications. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
|
-
- HY-B1257R
-
|
Bacterial
Antibiotic
|
Infection
Cancer
|
Cefmetazole (sodium) (Standard) is the analytical standard of Cefmetazole (sodium). This product is intended for research and analytical applications. Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
|
-
- HY-17452B
-
Cefditoren pivoxyl hydrochloride; Cefditoren pivaloyloxymethyl ester hydrochloride; ME 1207 hydrochloride
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
Cefditoren Pivoxil (ME 1207) hydrochloride is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .
|
-
- HY-13678AR
-
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
Cancer
|
Meropenem (trihydrate) (Standard) is the analytical standard of Meropenem (trihydrate). This product is intended for research and analytical applications. Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem trihydrate has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
|
-
- HY-13678S1
-
SM 7338-d6-1
|
Bacterial
Antibiotic
|
Infection
|
Meropenem-d6-1 (SM 7338-d6-1) is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
|
-
- HY-14879D
-
AVE1330A
|
Others
|
Infection
|
ent-Avibactam sodium (AVE1330A) is a new β-lactamase inhibitor with broad-spectrum antibacterial activity. ent-Avibactam sodium, in combination with ceftazidime, exhibits significant inhibitory effects on Enterobacteriaceae that produce Ambler class A and class C beta-lactamases. The IC50 value of ent-Avibactam sodium is much lower than the commonly used β-lactamase inhibitors clavulanic acid and ticarbonitrile, showing its ability to inhibit TEM-1 and P99 enzyme efficiency .
|
-
- HY-P3459A
-
|
Bacterial
|
Infection
|
Tet-213 TFA is a antimicrobial peptide. Tet-213 TFA has broad spectrum antibacterial activity. Tet-213 TFA can promote infected wound repair .
|
-
- HY-N7125R
-
|
Bacterial
|
Others
|
Cinnamyl acetate (Standard) is the analytical standard of Cinnamyl acetate. This product is intended for research and analytical applications. Cinnamyl acetate has a wide application in the flavor and fragrance industry . Cinnamyl acetate is a new broad spectrum antibacterial agent .
|
-
- HY-14865BR
-
|
Bacterial
Antibiotic
|
Infection
|
Omadacycline (tosylate) (Standard) is the analytical standard of Omadacycline (tosylate). This product is intended for research and analytical applications. Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
- HY-14865R
-
|
Bacterial
Antibiotic
|
Infection
|
Omadacycline (Standard) is the analytical standard of Omadacycline. This product is intended for research and analytical applications. Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
- HY-B0771
-
SCE-2787
|
Bacterial
Antibiotic
|
Infection
|
Cefozopran (SCE-2787) is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .
|
-
- HY-B0771A
-
SCE-2787 hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
Cefozopran (SCE-2787) hydrochloride is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran hydrochloride, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .
|
-
- HY-107330
-
|
Antibiotic
|
Others
|
(6R,7S)-Cefminox sodium heptahydrate is an isomer of Cefminox sodium heptahydrate. Cefminox sodium heptahydrate is a β-lactam cephalosporin antibiotic, which exhibits a broad spectrum of antibacterial activity .
|
-
- HY-123162A
-
Fortimicin A disulfate; KW-1070 disulfate
|
Antibiotic
Bacterial
|
Infection
|
Astromicin disulfate is a water-soluble aminoglycoside antibiotic that can be isolated from the genus Micromonospora. Astromicin disulfate exhibits broad spectrum antibacterial activity against gram positive and negative bacteria .
|
-
- HY-10581R
-
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
|
Gatifloxacin (Standard) is the analytical standard of Gatifloxacin. This product is intended for research and analytical applications. Gatifloxacin (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50=0.109 μg/ml) . Gatifloxacin can be used to treat bacterial conjunctivitis in vivo.
|
-
- HY-A0059
-
NF 113; SAP 113; Methylmercadone
|
Bacterial
Parasite
Antibiotic
Fungal
Apoptosis
STAT
Interleukin Related
TNF Receptor
|
Infection
Inflammation/Immunology
Cancer
|
Nifuratel (NF 113) is an orally active broad-spectrum antibiotic with antiprotozoal, antibacterial, anticancer and anti-inflammatory activities, and has good inhibitory effects on Candida and Trichomonas. Nifuratel is also a STAT3 inhibitor, which significantly inhibits the growth and proliferation of human gastric cancer cells and induces apoptosis. In addition, Nifuratel also inhibits mast cell-mediated antigen hypersensitivity reactions and can be used in the study of IgE-mediated allergic diseases .
|
-
- HY-B0239
-
|
Antibiotic
Bacterial
HIF/HIF Prolyl-Hydroxylase
VEGFR
Autophagy
Apoptosis
Beclin1
JNK
Akt
MMP
|
Infection
Cancer
|
Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .
|
-
- HY-10581CR
-
|
Bacterial
Topoisomerase
Antibiotic
|
Infection
Inflammation/Immunology
|
Gatifloxacin (sesquihydrate) (Standard) is the analytical standard of Gatifloxacin (sesquihydrate). This product is intended for research and analytical applications. Gatifloxacin sesquihydrate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin sesquihydrate inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml) . Gatifloxacin sesquihydrate can be used to treat bacterial conjunctivitis?in vivo.
|
-
- HY-B1190A
-
BL-S 578 hydrate
|
Bacterial
Antibiotic
|
Infection
|
Cefadroxil hydrate (BL-S 578 hydrate) is an orally active and first-generation cephalosporin with a broad spectrum antibacterial activity. Cefadroxil hydrate (BL-S 578 hydrate) also acts as a substrate of the peptide transporter PEPT1 and PEPT2 .
|
-
- HY-108402
-
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts .
|
-
- HY-N11667
-
|
Others
|
Infection
Cancer
|
18-O-Demethylpederin is a pederin analogue. Pederin is a natural polyketide compound extracted from Paederus for the first time. It is a non-protein insect toxin with a broad spectrum of biological activities, including antibacterial, antiviral, and antitumor .
|
-
- HY-120203
-
|
Antibiotic
Bacterial
|
Infection
|
DA 1131 is an anionic Carbapenem antibiotic. DA 1131 has broad spectrum antibacterial activity for both gram-positive and gram-negative organisms. DA 1131 is resistant to degradation by various types of β-lactamases .
|
-
- HY-108402A
-
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
Cefodizime sodium is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime sodium has no renal toxic effect, good tolerance and immune regulation activity, and can be used for the research of severe infections of the respiratory and urinary tracts .
|
-
- HY-W032013S2
-
-
- HY-17452AR
-
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
Inflammation/Immunology
|
Cefditoren Pivoxil (Standard) is the analytical standard of Cefditoren Pivoxil. This product is intended for research and analytical applications. Cefditoren Pivoxil (ME 1207) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections .
|
-
- HY-B1119
-
|
Bacterial
Fungal
Antibiotic
Apoptosis
|
Infection
Cancer
|
Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 µM and 10 µM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
|
-
- HY-121268A
-
|
Antibiotic
Bacterial
|
Infection
Inflammation/Immunology
Cancer
|
Demeclocycline (calcium) is an orally active tetracycline antibiotic that inhibits the binding of aminoacyl tRNA by binding to the 30S ribosomal subunit, thereby affecting protein synthesis. Demeclocycline (calcium) exhibits antibacterial activity against a broad spectrum of bacterial infections .
|
-
- HY-B1802CR
-
|
Antibiotic
Bacterial
|
Infection
|
Tosufloxacin (tosylate) (Standard) is the analytical standard of Tosufloxacin (tosylate). This product is intended for research and analytical applications. Tosufloxacin (A-61827) tosylate is an orally active fluoroquinolone antibiotic. Tosufloxacin tosylate shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria .
|
-
- HY-B0239R
-
|
Antibiotic
Bacterial
HIF/HIF Prolyl-Hydroxylase
VEGFR
Autophagy
Apoptosis
Beclin1
JNK
Akt
MMP
|
Infection
Cancer
|
Chloramphenicol (Standard) is the analytical standard of Chloramphenicol. This product is intended for research and analytical applications. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research .
|
-
- HY-N8213
-
-
- HY-N7101
-
U-76,252; CS-807
|
Bacterial
Antibiotic
Penicillin-binding protein (PBP)
|
Infection
|
Cefpodoxime proxetil is an orally administered broad spectrum third-generation cephalosporin. Cefpodoxime proxetil has anti-bacterial activity. Cefpodoxime proxetil binds to penicillin binding proteins (PBPs) which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis .
|
-
- HY-W250308
-
Epsilon-polylysine (MW 3800-4200); ε-Polylysine (MW 3800-4200); ε-PL (MW 3800-4200)
|
Bacterial
|
Others
|
Epsilon-polylysine is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine is also used as a liposome stabilizer .
|
-
- HY-B0239S2
-
|
JNK
Apoptosis
VEGFR
MMP
Bacterial
Akt
Autophagy
HIF/HIF Prolyl-Hydroxylase
Antibiotic
Beclin1
|
Cancer
|
Threo-Chloramphenicol-d6 is the deuterium labeled Chloramphenicol[1]. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research[2][3][4].
|
-
- HY-B1119R
-
|
Bacterial
Fungal
Antibiotic
Apoptosis
|
Infection
Cancer
|
Triclosan (Standard) is the analytical standard of Triclosan. This product is intended for research and analytical applications. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 µM and 10 µM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
|
-
- HY-117736
-
|
Penicillin-binding protein (PBP)
Bacterial
|
Infection
Inflammation/Immunology
|
Ro 09-1428 is a broad-spectrum parenteral cephalosporin. Ro 09-1428 has potent antibacterial activities against Pseudomonas aeruginosa and Acinetobacter caloaceticus, with MIC90s of 0.39 and 6.25 μg/mL, respectively, better than Ceftazidime (HY-B0593). Additionally, Ro 09-1428 shows high activity against Escherichia coli, Kkbsielia pneumoniae, Proteus mirabilis, P. aeruginosa, staphylococci, and more. Ro 09-1428 preferentially attacks PBP 3 for target in E. coli and P. aeruginosa, which is promising for research of septicemias and serious P. aeruginosa infections .
|
-
- HY-B0771AR
-
|
Bacterial
Antibiotic
|
Infection
|
Cefozopran (hydrochloride) (Standard) is the analytical standard of Cefozopran (hydrochloride). This product is intended for research and analytical applications. Cefozopran (SCE-2787) hydrochloride is a semi-synthetic, parenteral, fourth-generation cephalosporin. Cefozopran hydrochloride, an antibiotic, has a broad spectrum of antibacterial activity, inhibiting most of the gram-negative and gram-positive organisms .
|
-
- HY-155007
-
|
Bacterial
|
Infection
|
DNA gyrase B-IN-2 (Compound E) is a 2-aminobenzothiazole-based DNA gyrase B inhibitor with promising activity against ESKAPE bacterial pathogens. DNA gyrase B-IN-2 showed low nanomolar inhibition of DNA gyrase (IC50 < 10 nM) and broad-spectrum antibacterial activity against pathogens belonging to the ESKAPE group, with the minimum inhibitory concentration < 0.03 μg/mL for most Gram-positive strains and 4–16 μg/mL against Gram-negative E. coli, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae.DNA gyrase B-IN-2 can be used for the research of infection .
|
-
- HY-W250308A
-
Epsilon-polylysine hydrochloride (MV 2000-5000); ε-Polylysine hydrochloride (MV 2000-5000); ε-PL hydrochloride (MV 2000-5000)
|
Bacterial
|
Infection
|
ε-Poly-L-lysine hydrochloride (MV 2000-5000) is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine hydrochloride inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine hydrochloride has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine hydrochloride can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine hydrochloride is also used as a liposome stabilizer .
|
-
- HY-149155
-
|
Others
|
Infection
|
o-Cymen-5-ol is a broad-spectrum antimicrobial agent with direct antimicrobial activity. o-Cymen-5-ol showed effective minimum inhibitory concentrations (MICs) against a variety of bacteria and fungi, such as Streptococcus mutans and Candida albicans. The combination of o-Cymen-5-ol and zinc showed synergistic effects, enhancing the inhibitory effect against oral pathogens. o-Cymen-5-ol was able to inhibit the glycolysis process and co-enhanced this effect with zinc. o-Cymen-5-ol showed a stronger antibacterial effect in toothpaste than placebo .
|
-
- HY-108402R
-
|
Penicillin-binding protein (PBP)
Bacterial
Antibiotic
|
Infection
|
Cefodizime (Standard) is the analytical standard of Cefodizime. This product is intended for research and analytical applications. Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts .
|
-
- HY-B1805
-
3,4,4′-Trichlorocarbanilide
|
Bacterial
|
Infection
|
Triclocarban (3,4,4′-Trichlorocarbanilide), a broad spectrum antibacterial compound, is widely used in a broad range of applications such as the production of soaps, skin creams, toothpastes and deodorants. Triclocarban is a potential endocrine-disrupting chemical with the capacity to modulate androgen and estrogen activities as well as other hormone-mediated biological processes .
|
-
- HY-126637
-
|
Bacterial
Fungal
|
Infection
|
Marasmic acid is a sesquiterpenoid with unsaturated dialdehyde functionality, first isolated from the Basidiomycete Marasmus conigenus. Marasmic acid has antibacterial, antifungal, cytotoxic and mutagenic activities, and its broad-spectrum activity is related to the α,β-unsaturated aldehyde group. However, its detailed biological mechanism of action has not been clarified. Previous studies have suggested that marasmic acid may exert its effects by reacting with endogenous nucleophiles or forming pyrrole derivatives. This study found that marasmic acid interferes with the membrane sensor histidine kinase MoSln1p of M. oryzae, superactivates the HOG pathway and causes cell death, indicating that its mechanism of action is different from other unsaturated dialdehyde sesquiterpenoids.
|
-
- HY-P3350
-
|
Bacterial
|
Infection
|
LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].
|
-
- HY-128932
-
MT-141
|
Bacterial
PPAR
Prostaglandin Receptor
Antibiotic
|
Infection
Cardiovascular Disease
Endocrinology
|
Cefminox sodium (MT-141) is a semisynthetic cephamycin, which exhibits a broad spectrum of antibacterial activity . Cefminox sodium (MT-141) also acts as a dual agonist of prostacyclin receptor (IP) and PPARγ, upregulates cAMP production and PTEN expression and inhibits Akt/mTOR signaling. Cefminox sodium (MT-141) also prevents pulmonary arterial hypertension .
|
-
- HY-N7101R
-
|
Bacterial
Antibiotic
Penicillin-binding protein (PBP)
|
Infection
|
Cefpodoxime Proxetil (Standard) is the analytical standard of Cefpodoxime Proxetil. This product is intended for research and analytical applications. Cefpodoxime proxetil is an orally administered broad spectrum third-generation cephalosporin. Cefpodoxime proxetil has anti-bacterial activity. Cefpodoxime proxetil binds to penicillin binding proteins (PBPs) which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis .
|
-
- HY-146075
-
|
Beta-lactamase
Bacterial
|
Infection
|
β-Lactamase-IN-8 (compound 20) is a potent and oral bioavailable broad-spectrum cyclic boronate β-lactamase inhibitor. β-Lactamase-IN-8 can be used for researching antibacteria .
|
-
- HY-B1805S
-
3,4,4′-Trichlorocarbanilide-d4
|
Bacterial
|
Infection
|
Triclocarban-d4 is the deuterium labeled Triclocarban. Triclocarban (3,4,4′-Trichlorocarbanilide), a broad spectrum antibacterial compound, is widely used in a broad range of applications such as the production of soaps, skin creams, toothpastes and deodorants. Triclocarban is a potential endocrine-disrupting chemical with the capacity to modulate androgen and estrogen activities as well as other hormone-mediated biological processes[1][2][3].
|
-
- HY-P3626
-
SPL7013 free base
|
Bacterial
HCV
SARS-CoV
|
Infection
|
Astodrimer (SPL7013 free base) is a large (3-4 nm, ~ 16.5 kDa), negatively charged, highly-branched dendrimer, is a potent virucidal agent. Astodrimer shows antiviral and virucidal activity against a broad spectrum of viruses, including SARS-CoV-2, HIV-1, HSV-1, HSV-2, HPV. Astodrimer also has antibacterial properties .
|
-
- HY-128932R
-
|
Bacterial
PPAR
Prostaglandin Receptor
Antibiotic
|
Infection
Cardiovascular Disease
Endocrinology
|
Cefminox (sodium) (Standard) is the analytical standard of Cefminox (sodium). This product is intended for research and analytical applications. Cefminox sodium (MT-141) is a semisynthetic cephamycin, which exhibits a broad spectrum of antibacterial activity . Cefminox sodium (MT-141) also acts as a dual agonist of prostacyclin receptor (IP) and PPARγ, upregulates cAMP production and PTEN expression and inhibits Akt/mTOR signaling. Cefminox sodium (MT-141) also prevents pulmonary arterial hypertension .
|
-
- HY-139554
-
KBP-7072
|
Bacterial
|
Infection
|
Zifanocycline (KBP-7072) is a semisynthetic third-generation aminomethylcycline antibiotic that inhibits the normal function of the bacterial ribosome. Zifanocycline exhibits a broad spectrum of in vitro antibacterial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline is available in both oral and injectable formulations. Zifanocycline can be used for the research of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .
|
-
- HY-B0712
-
Ro 13-9904 free acid
|
Bacterial
Antibiotic
GSK-3
Aurora Kinase
|
Infection
Inflammation/Immunology
Cancer
|
Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .
|
-
- HY-B0712A
-
Ro 13-9904 sodium hydrate
|
Bacterial
Antibiotic
GSK-3
Aurora Kinase
|
Infection
Cancer
|
Ceftriaxone sodium hydrate (Ro 13-9904 sodium hydrate) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium hydrate is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone sodium hydrate is an inhibitor of Aurora B. Ceftriaxone sodium hydrate has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium hydrate can be used in the study of bacterial infections and meningitis .
|
-
- HY-B0712B
-
Ro 13-9904
|
Antibiotic
GSK-3
Bacterial
Aurora Kinase
|
Infection
Inflammation/Immunology
Cancer
|
Ceftriaxone sodium salt (Ro 13-9904) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium salt is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone sodium salt is an inhibitor of Aurora B. Ceftriaxone sodium salt has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium salt can be used in the study of bacterial infections and meningitis .
|
-
- HY-105088A
-
MSI 78
|
Bacterial
|
Infection
|
Pexiganan acetate (MSI 78) is the acetate salt form of Pexiganan (HY-105088). Pexiganan acetate is an orally active broad-spectrum antimicrobial peptide, which inhibits 99% gram-positive and Gram-negative aerobic bacteria through disruption of cell membrane/cells permeability. Pexiganan acetate can be used in the research of infections, such as diabetic foot ulcer infections .
|
-
- HY-D0027
-
Coumarin 120; AMC
|
Fluorescent Dye
Antibiotic
Fungal
|
Infection
|
7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively.
|
-
- HY-B0712AR
-
|
Bacterial
Antibiotic
GSK-3
Aurora Kinase
|
Infection
Cancer
|
Ceftriaxone (sodium hydrate) (Standard) is the analytical standard of Ceftriaxone (sodium hydrate). This product is intended for research and analytical applications. Ceftriaxone sodium hydrate (Ro 13-9904 sodium hydrate) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone sodium hydrate is a covalent inhibitor of GSK3β with IC50 value of 0.78 μM. Ceftriaxone sodium hydrate is an inhibitor of Aurora B. Ceftriaxone sodium hydrate has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone sodium hydrate can be used in the study of bacterial infections and meningitis .
|
-
- HY-B0455B
-
SC47111A (aspartate)
|
Bacterial
Antibiotic
|
Infection
|
Lomefloxacin (SC47111A) aspartate is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin aspartate can be used for researching respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. .
|
-
- HY-B0712S1
-
Ro 13-9904-13C2,d3 triethylammonium salt
|
Antibiotic
Aurora Kinase
GSK-3
Bacterial
Isotope-Labeled Compounds
|
Infection
Inflammation/Immunology
Cancer
|
Ceftriaxone- 13C2,d3 triethylammonium salt is 13C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .
|
-
- HY-16745
-
KRP-AM1977
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
Lascufloxacin (KRP-AM1977X) is a potent and orally active fluoroquinolone antibacterial agent. Lascufloxacin potently inhibits infections caused by various pathogens, including quinolone-resistant strains. Lascufloxacin has the potential for various infectious diseases treatment, including lower respiratory tract infections .
|
-
- HY-D0027R
-
|
Fluorescent Dye
Antibiotic
Fungal
|
Infection
|
7-Amino-4-methylcoumarin (Standard) is the analytical standard of 7-Amino-4-methylcoumarin. This product is intended for research and analytical applications. 7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively. [4]
|
-
Cat. No. |
Product Name |
Type |
-
- HY-D0027
-
Coumarin 120; AMC
|
Fluorescent Dyes/Probes
|
7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively.
|
-
- HY-D0027R
-
|
Fluorescent Dyes/Probes
|
7-Amino-4-methylcoumarin (Standard) is the analytical standard of 7-Amino-4-methylcoumarin. This product is intended for research and analytical applications. 7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively. [4]
|
Cat. No. |
Product Name |
Type |
-
- HY-W250302
-
|
Biochemical Assay Reagents
|
Methylbenzethonium chloride is a quaternary ammonium compound commonly used as a preservative and disinfectant in a variety of personal care and healthcare products. Methylbenzethonium chloride has several properties that make it suitable for these applications, including its broad-spectrum antibacterial activity against bacteria, viruses and fungi. In addition, it is used as a preservative in cosmetic and pharmaceutical formulations to prevent the growth of microorganisms.
|
-
- HY-W250308
-
Epsilon-polylysine (MW 3800-4200); ε-Polylysine (MW 3800-4200); ε-PL (MW 3800-4200)
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Cell Assay Reagents
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Epsilon-polylysine is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine is also used as a liposome stabilizer .
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- HY-W250308A
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Epsilon-polylysine hydrochloride (MV 2000-5000); ε-Polylysine hydrochloride (MV 2000-5000); ε-PL hydrochloride (MV 2000-5000)
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Cell Assay Reagents
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ε-Poly-L-lysine hydrochloride (MV 2000-5000) is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine hydrochloride inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine hydrochloride has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine hydrochloride can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine hydrochloride is also used as a liposome stabilizer .
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- HY-W740053
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Microbial Culture
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Meropenem sodium is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem sodium has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P2460
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Bacterial
Fungal
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Infection
Inflammation/Immunology
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SMAP-29, a promising antiinfective agent, is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide. SMAP-29 acts by permeabilizing bacterial membranes and inducing remarkable changes in the surface morphology of susceptible microorganism .
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- HY-P3459A
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Bacterial
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Infection
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Tet-213 TFA is a antimicrobial peptide. Tet-213 TFA has broad spectrum antibacterial activity. Tet-213 TFA can promote infected wound repair .
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- HY-P5691
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Bacterial
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Infection
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P1 is a broad-spectrum antimicrobial peptide. P1 shows antibacterial activity against Gram-positive and Gram-negative bacteria,such as B. anthracis spores and Carbapenem-resistant A. baumannii and K. pneumoniae .
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- HY-P5561
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Antibiotic
Bacterial
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Infection
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Aurein 2.2 is a major component of the skin secretion of L.aurea. Aurein 2.2 is an antibiotic with broad-spectrum antibacterial activity against Gram positive bacteria such as Staphylococcus aureus and S. epidermidis .
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- HY-P10431
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Sea snake cathelicidin
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Bacterial
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Infection
Inflammation/Immunology
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Hc-CATH (Sea snake cathelicidin) is an antibacterial peptide with broad-spectrum. Hc-CATH inhibits Shigella dysenteriae and Klebsiella pneumoniae with MIC of 0.16 mM-20.67 mM. Hc-CATH exhibits anti-inflammatory efficacy .
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- HY-P5724
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Bacterial
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Infection
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Nv-CATH is an antibacterial peptide of frog origin. Nv-CATH has broad-spectrum antibacterial activity against gram-positive and gram-negative bacteria. Nv-CATH significantly protects mice from fatal infections caused by Staphylococcus aureus. Nv-CATH protects mice from bacterial infection through antimicrobial immunoregulatory duality .
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- HY-P10228
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Fungal
Bacterial
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Infection
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S-Thanatin is an insect antimicrobial peptide with potent broad-spectrum antibacterial activity. S-Thanatin can inhibit the activity of Gram-negative bacteria, Gram-positive bacteria, and fungi, without cytotoxicity. The antibacterial activity of S-Thanatin is not affected by PH value, but monovalent cations (Na +/K +) can reduce its antibacterial activity against Gram-negative bacteria in a dose-dependent manner .
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- HY-P3459
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Bacterial
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Infection
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Tet-213 is a antimicrobial peptide. Tet-213 has broad spectrum antibacterial activity. Tet-213 can promote infected wound repair .
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- HY-P3350
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Bacterial
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Infection
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LS-BF1 is a stable and low toxic cationic antimicrobial peptide. LS-BF1 displays broad spectrum of antibacterial activity, including the challenging ESKAPE pathogens, by cell membrane disruptive mechanism. LS-BF1 shows good in vivo efficacy for elimination of bacteria in a mouse infection model[1].
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- HY-P3626
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SPL7013 free base
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Bacterial
HCV
SARS-CoV
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Infection
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Astodrimer (SPL7013 free base) is a large (3-4 nm, ~ 16.5 kDa), negatively charged, highly-branched dendrimer, is a potent virucidal agent. Astodrimer shows antiviral and virucidal activity against a broad spectrum of viruses, including SARS-CoV-2, HIV-1, HSV-1, HSV-2, HPV. Astodrimer also has antibacterial properties .
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- HY-105088A
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MSI 78
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Bacterial
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Infection
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Pexiganan acetate (MSI 78) is the acetate salt form of Pexiganan (HY-105088). Pexiganan acetate is an orally active broad-spectrum antimicrobial peptide, which inhibits 99% gram-positive and Gram-negative aerobic bacteria through disruption of cell membrane/cells permeability. Pexiganan acetate can be used in the research of infections, such as diabetic foot ulcer infections .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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- HY-N7111
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- HY-N7449
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- HY-W018025
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- HY-16468
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- HY-N7112
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- HY-N13140
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- HY-B0529R
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Microorganisms
Source classification
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Bacterial
Parasite
Antibiotic
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Azlocillin (Standard) is the analytical standard of Azlocillin. This product is intended for research and analytical applications. Azlocillin, an antibiotic, is a semisynthetic penicillin, and has broad-spectrum antibacterial activity. Azlocillin is active against drug-tolerant B. burgdorferi sensu stricto JLB31 infection .
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- HY-137139
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- HY-130066
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- HY-W018025R
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- HY-N7125
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- HY-13678
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- HY-N3139
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- HY-117108
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- HY-B1802A
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- HY-13678R
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- HY-N7125R
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- HY-B0239
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- HY-N11667
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- HY-B0239R
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- HY-N8213
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- HY-126637
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Structural Classification
Microorganisms
Antibiotics
Source classification
Other Antibiotics
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Bacterial
Fungal
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Marasmic acid is a sesquiterpenoid with unsaturated dialdehyde functionality, first isolated from the Basidiomycete Marasmus conigenus. Marasmic acid has antibacterial, antifungal, cytotoxic and mutagenic activities, and its broad-spectrum activity is related to the α,β-unsaturated aldehyde group. However, its detailed biological mechanism of action has not been clarified. Previous studies have suggested that marasmic acid may exert its effects by reacting with endogenous nucleophiles or forming pyrrole derivatives. This study found that marasmic acid interferes with the membrane sensor histidine kinase MoSln1p of M. oryzae, superactivates the HOG pathway and causes cell death, indicating that its mechanism of action is different from other unsaturated dialdehyde sesquiterpenoids.
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- HY-105088A
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MSI 78
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Structural Classification
Natural Products
Animals
Source classification
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Bacterial
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Pexiganan acetate (MSI 78) is the acetate salt form of Pexiganan (HY-105088). Pexiganan acetate is an orally active broad-spectrum antimicrobial peptide, which inhibits 99% gram-positive and Gram-negative aerobic bacteria through disruption of cell membrane/cells permeability. Pexiganan acetate can be used in the research of infections, such as diabetic foot ulcer infections .
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Cat. No. |
Product Name |
Chemical Structure |
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- HY-B0210S
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Cefoperazone-d5 is deuterium labeled Cefoperazone. Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity[1].
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- HY-13678S
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Meropenem-d6 is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL)[1][2].
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- HY-B1805S
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Triclocarban-d4 is the deuterium labeled Triclocarban. Triclocarban (3,4,4′-Trichlorocarbanilide), a broad spectrum antibacterial compound, is widely used in a broad range of applications such as the production of soaps, skin creams, toothpastes and deodorants. Triclocarban is a potential endocrine-disrupting chemical with the capacity to modulate androgen and estrogen activities as well as other hormone-mediated biological processes[1][2][3].
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- HY-135393S
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Sulfadimethoxypyrimidine-d4 is a deuterium labeled Sulfadimethoxypyrimidine. Sulfadimethoxypyrimidine is a sulfonamide antibiotic with a broad-spectrum antibacterial effect[1].
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- HY-10581AS
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Gatifloxacin-d3 (hydrochloride) is the deuterium labeled Gatifloxacin (hydrochloride). Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo.
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- HY-13678S1
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Meropenem-d6-1 (SM 7338-d6-1) is the deuterium labeled Meropenem. Meropenem (SM 7338) is a carbapenem antibiotic with broad-spectrum antibacterial activity. Meropenem has activity against susceptible and resistant N. gonorrhoeae (MIC value of 0.02-0.06 mg/mL), H. influenzae (MIC value of 0.03-0.12 mg/mL), and H. ducreyi (MIC value of 0.015-0.12 mg/mL) .
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- HY-W032013S2
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1-Octanol-d2-1 is deuterated labeled Cinnamyl acetate (HY-N7125). Cinnamyl acetate has a wide application in the flavor and fragrance industry . Cinnamyl acetate is a new broad spectrum antibacterial agent .
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- HY-B0239S2
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Threo-Chloramphenicol-d6 is the deuterium labeled Chloramphenicol[1]. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research[2][3][4].
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- HY-B0712S1
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Ceftriaxone- 13C2,d3 triethylammonium salt is 13C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .
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