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Results for "

serpin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) Biochemical Assay Reagents (1) PAI-1 (3) Ser/Thr Protease (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Infection (1) Neurological Disease (1)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Targets Recommended: Serpin

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-33299

Serpin B9-IN-1 BTCA	Biochemical Assay Reagents	Cancer
Serpin B9-IN-1 (BTCA) is an inhibitor that specifically targets Serpin B9 (SB9); SB9 is a natural inhibitor of granzyme B (GrB) , but may promote the metastasis of lung cancer cells into the bone marrow. SB9-overexpressing cancer cells promote proliferation and metastasis in an immune cell-dependent manner by binding to GrB. Inhibition of SB9 by Serpin B9-IN-1 significantly inhibits immunotherapy of lung cancer bone metastases in the caudal artery (CA) mouse model (LCBM) .

HY-E70194

Endoproteinase Glu-C V8 protease; Glu-C	Ser/Thr Protease	Others
Endoproteinase GluC (V8 protease) is a serine proteinase. Endoproteinase GluC is able to hydrolyze some serpins and all classes of mammalian immunoglobulins .

HY-150514

ARN1468	PAI-1	Infection
ARN1468 (compound 5) is an orally active and potent *serpins* inhibitor. ARN1468 can inhibit serpins activity would set the protease free to further reduce prion accumulation. ARN1468 shows anti-prion effect in ScGT1 RML, ScGT1 22L, ScN2a RML, and ScN2a 22L cell lines, with EC₅₀ values of 8.64, 19.3, 11.2, and 6.27 μM .

HY-14759

Aleplasinin PAZ-417	PAI-1 Amyloid-β	Neurological Disease
Aleplastinin (PAZ-417) is an orally active, blood-brain barrier permeable, selective SERPINE1 (PAI-1) inhibitor (IC₅₀=655 nM). Aleplastinin activates the tissue type plasminogen activator (tPA)/fibrinolysis cascade by inhibiting PAI-1, thereby promoting the degradation of amyloid-β (Aβ) oligomers and monomers. Aleplastinin can significantly reduce plasma and brain Aβ levels, improve memory impairment, and reverse cognitive impairment. Aleplastinin can be used for research on Alzheimer's disease .

HY-RS12707

SERPINB11 Human Pre-designed siRNA Set A EPIPIN; serpin11	Small Interfering RNA (siRNA)	Others
SERPINB11 Human Pre-designed siRNA Set A contains three designed siRNAs for SERPINB11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SERPINB11 Human Pre-designed siRNA Set A SERPINB11 Human Pre-designed siRNA Set A

HY-P991422

Stromab DS9231; TS-23; CSL-301	PAI-1	Cardiovascular Disease
Stromab (DS9231; TS-23; CSL-301) is a human IgG1 monoclonal antibody (mAb) targeting Serpin F2. Stromab can be used in schaemic stroke, Pulmonary embolism, Myocardial infarction and Thrombosis research. Recommended isotype control: Human IgG1 lambda, Isotype Control (HY-P99992) .

Cat. No.	Product Name	Target	Research Area

HY-P991422

Stromab DS9231; TS-23; CSL-301	PAI-1	Cardiovascular Disease
Stromab (DS9231; TS-23; CSL-301) is a human IgG1 monoclonal antibody (mAb) targeting Serpin F2. Stromab can be used in schaemic stroke, Pulmonary embolism, Myocardial infarction and Thrombosis research. Recommended isotype control: Human IgG1 lambda, Isotype Control (HY-P99992) .

Recombinant Proteins Recommended:

Serpin (Protease Inhibitor)

Species:	Human (34) Mouse (27) Rat (8) Cynomolgus (2) Pig (1)
Tag:	His (63) Tag Free (5) Avi (1) Myc (1) GST (1) Trx (1) Fc (3)
Source:	HEK293 (56) CHO (1) Sf9 insect cells (7) P. pastoris (1) E. coli (7)

Cat. No.	Compare	Product Name	Species	Source

HY-P7385A

	Serpin B5/Maspin Protein, Human (His) rHuMaspin; serpin B5; PI-5	Human	E. coli
	Serpin B5/Maspin Protein is a tumor suppressor and a unique member of the serpin family. Maspin inhibits cancer cell invasion, attachment to the extracellular matrix, increases sensitivity to apoptosis, and inhibits angiogenesis. Maspin interacting with diverse group of intercellular and extracellular proteins, regulating cell adhesion, motility, apoptosis, and critically involved in mammary gland development. Maspin acts as an endogenous inhibitor of histone deacetylase (HDAC1). Serpin B5/Maspin Protein, Human (His) is the recombinant human-derived Serpin B5/Maspin protein, expressed by E. coli , with C-6*His labeled tag.

HY-P76060

	Serpin A11 Protein, Mouse (HEK293, His) serpin A11; serpina11; Gm895	Mouse	HEK293
	Serpin A11 protein is a member of the serpin family and is an important serine protease inhibitor that regulates proteolytic activity. Its study deepens our understanding of cellular processes related to proteolysis and has potential applications in therapy. Serpin A11 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A11 protein, expressed by HEK293 , with C-His labeled tag.

HY-P7385

	Serpin B5/Maspin Protein, Human (375 a.a) rHuMaspin; serpin B5; PI-5	Human	E. coli
	Serpin B5/Maspin Protein, Human (375 a.a) could inhibit invasion and motility of mammary tumors. Maspin Protein, Human is also found to be a potent angiogenesis inhibitor.

HY-P73651

	Serpin A8/Angiotensinogen Protein, Rat (HEK293, His) Angiotensinogen; serpin A8; AGT; serpinA8	Rat	HEK293
	Serpin A8 (or angiotensinogen) is a key regulator of the renin-angiotensin system, affecting blood pressure, fluid and electrolyte balance.As a vasoconstrictor, it directly affects vascular smooth muscle and affects myocardial contractility and heart rate through the sympathetic nervous system.Serpin A8/Angiotensinogen Protein, Rat (HEK293, His) is the recombinant rat-derived Serpin A8/Angiotensinogen protein, expressed by HEK293 , with C-His labeled tag.

HY-P73652

	Serpin A8/Angiotensinogen Protein, Mouse (HEK293, His) Angiotensinogen; serpin A8; AGT; serpinA8	Mouse	HEK293
	Serpin A8 (or angiotensinogen) is an important regulator in the renin-angiotensin system, fine-tuning blood pressure and electrolyte balance. This multifunctional protein acts as a potent vasoconstrictor, affecting vascular smooth muscle and affecting cardiac function via the sympathetic nervous system. Serpin A8/Angiotensinogen Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A8/Angiotensinogen protein, expressed by HEK293 , with C-His labeled tag.

HY-P73653

	Serpin A8/Angiotensinogen Protein, Human (HEK293, His) Angiotensinogen; serpin A8; AGT; serpinA8	Human	HEK293
	Serpin A8/angiotensinogen protein is an important component of the renin-angiotensin system (RAS), which regulates blood pressure, fluid balance, and electrolyte homeostasis. Serpin A8/Angiotensinogen Protein, Human (HEK293, His) is the recombinant human-derived Serpin A8/Angiotensinogen protein, expressed by HEK293 , with C-His labeled tag.

HY-P72477

	Serpin A8/Angiotensinogen Protein, Human (HEK293, His, solution) Angiotensinogen; serpin A8; AGT and serpinA8	Human	HEK293
	Serpin A8/angiotensinogen protein is an important component of the renin-angiotensin system (RAS), which regulates blood pressure, fluid balance, and electrolyte homeostasis. Serpin A8/Angiotensinogen Protein, Human (HEK293, His, solution) is the recombinant human-derived Serpin A8/Angiotensinogen protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P74556

	Serpin A1 Protein, Rat (HEK293, His) Alpha-1-antiproteinase; serpin A1; A1A	Rat	HEK293
	The serpin A1 protein is a vigilant guardian in cell regulation, effectively inhibiting elastase and providing a strong barrier to its enzymatic activity.Serpin A1 has moderate affinity for plasmin and thrombin and exhibits versatility in binding a range of serine proteases.Serpin A1 Protein, Rat (HEK293, His) is the recombinant rat-derived Serpin A1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P71304

	Serpin B12 Protein, Human (HEK293, His) serpinB12; serpin B12; Serine Protease Inhibitor-clade B12	Human	HEK293
	Serpin B12 Protein inhibits trypsin and plasmin, excluding thrombin, coagulation factor Xa, or urokinase-type plasminogen activator. It may have a role in cell differentiation, interacting with SLFN12 in a pathway regulating differentiation, and potentially interacting with USP14. Serpin B12 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B12 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73372

	Serpin F1 Protein, Mouse (HEK293, His) 1 Publications Verification Pigment epithelium-derived factor; Pedf; Sdf3; Caspin; serpin F1	Mouse	HEK293
	Serpin F1 is a neurotrophin that significantly induces extensive neuronal differentiation of retinoblastoma cells and exhibits potent anti-angiogenic effects.Its unique conformation lacks the S (stress) to R (relaxation) transition typical of active serpins, resulting in a lack of serpin activity.Serpin F1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin F1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P73412

	Serpin A3 Protein, Human (HEK293, His) Alpha-1-Antichymotrypsin; ACT; serpin A3; serpinA3; AACT	Human	HEK293
	Serpin A3 protein is a serine protease inhibitor on chromosome 14 that affects protease targeting through tissue-specific polymorphisms. Sequence variants are associated with Alzheimer's disease, while deficiencies are associated with liver disease. Serpin A3 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A3 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74557

	Serpin F1 Protein, Rat (HEK293, His) Pigment epithelium-derived factor; Pedf; Sdf3; Caspin; serpin F1	Rat	HEK293
	Serpin F1 protein is part of the secreted Frizzled-related protein (sFRP) family and regulates the Wnt signaling pathway. As a member, Serpin F1 may interact with Wnt ligands and Frizzled receptors to regulate key cellular processes. Serpin F1 Protein, Rat (HEK293, His) is the recombinant rat-derived Serpin F1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P77197

	Serpin B12 Protein, Mouse (sf9, His) serpinB12; serpin B12; Serine Protease Inhibitor-clade B12	Mouse	Sf9 insect cells
	Serpin B12 inhibits trypsin and plasmin but not thrombin, coagulation factor Xa, and urokinase-type plasminogen activator. Additionally, it interacts with SLFN12, contributing to cellular differentiation pathways, showcasing its multifunctional nature beyond classical protease inhibition. Serpin B12 Protein, Mouse (sf9, His) is the recombinant mouse-derived Serpin B12 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P71079

	Serpin A7 Protein, Human (HEK293, His) Thyroxine-Binding Globulin; serpin A7; T4-Binding Globulin; serpinA7; TBG	Human	HEK293
	Serpin A7, or thyroxine-binding globulin (TBG), acts as a glycoprotein carrier for thyroid hormones, specifically binding and transporting thyroxine (T4) and triiodothyronine (T3). TBG regulates the availability and distribution of thyroid hormones critical for physiological processes like metabolism and growth. Mutations in the SERPINA7 gene can affect TBG function, influencing thyroid hormone levels. Serpin A7 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A7 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73656

	Serpin A7 Protein, Mouse (HEK293, His) Thyroxine-Binding Globulin; serpin A7; T4-Binding Globulin; serpinA7; TBG	Mouse	HEK293
	Serpin A7 protein binds hormones and inhibits serine-type endopeptidase activity. It is involved in negative regulation of endopeptidase activity, response to vitamin A, and thyroid hormone transport. It is located in the extracellular region and is active in the extracellular space. Serpin A7 is orthologous to human SERPINA7 and is expressed primarily in liver E18, liver E14.5, and two other tissues. Serpin A7 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A7 protein, expressed by HEK293 , with C-His labeled tag.

HY-P77198

	Serpin B4 Protein, Human (sf9, His) serpin B4; Leupin; Peptidase inhibitor 11; PI-11; SCCA-2	Human	Sf9 insect cells
	Serpin B4 is a protease inhibitor that may modulate the host immune response against tumor cells, suggesting a crucial role in fine-tuning immune balance. Its ability to inhibit proteases emphasizes its importance in influencing key regulatory pathways, enhancing the immune system's effectiveness against cancer cells. Serpin B4 Protein, Human (sf9, His) is the recombinant human-derived Serpin B4 protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P73336

	Serpin E1 Protein, Rat (HEK293, Fc) Plasminogen activator inhibitor 1; PAI-1; serpin E1; serpine1; Planh1	Rat	HEK293
	Serpin E1 is a serine protease inhibitor that regulates TMPRSS7 and inhibits tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU).It can significantly downregulate fibrinolysis and control thrombus degradation.Serpin E1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Serpin E1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P73655

	Serpin E1 Protein, Rat (HEK293, His) Plasminogen activator inhibitor 1; PAI-1; serpin E1; serpine1; Planh1	Rat	HEK293
	Serpin E1 Protein, Rat (HEK293, His) is one important member of the serine proteinase inhibitor E superfamily that plays a crucial role in the fibrinolytic system. The Serpin E1 protein is a single-chain glycoprotein composed of 379 amino acids. The active site of the protein is Arg346-Met347. SERPINE1 encodes plasminogen activator inhibitor type 1 (PAI-1), which serves as the primary inhibitor of urokinase plasminogen activator (uPA) and tissue-type plasminogen activator (tPA). The Serpin E1 protein can quickly inhibit the formation of plasmin. Serpin E1 can be transcribed through several signaling cascades, including pro-fibrogenic and pro-inflammatory pathways. Serpin E1 is a serine proteinase inhibitor, serves as an important regulator of extracellular matrix remodeling. Serpin E1 Protein, Rat (HEK293, His) is the recombinant rat-derived Serpin E1 protein, expressed by HEK293 , with C-His, C-10*His labeled tag.

HY-P70584

	Serpin F1 Protein, Mouse (375a.a) Pigment epithelium-derived factor; Pedf; Sdf3; Caspin; serpin F1; Stromal cell-derived factor 3.	Mouse	E. coli
	Serpin F1 is a neurotrophin that significantly induces extensive neuronal differentiation of retinoblastoma cells and exhibits potent anti-angiogenic effects.Its unique conformation lacks the S (stress) to R (relaxation) transition typical of active serpins, resulting in a lack of serpin activity.Serpin F1 Protein, Mouse is the recombinant mouse-derived Serpin F1 protein, expressed by E.coli , with tag free.

HY-P71292

	Serpin A10 Protein, Human (HEK293, His) Protein Z-Dependent Protease Inhibitor; PZ-Fependent Protease Inhibitor; PZI; serpin A10; serpinA10; ZPI	Human	HEK293
	Serpin A10 protein inhibits coagulation proteases, such as factor Xa, in the presence of PROZ, calcium, and phospholipids. It can also inhibit factor XIa without cofactors. Serpin A10 interacts with PROZ to exert its inhibitory effects on these coagulation factors. Serpin A10 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A10 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71302

	Serpin A3N Protein, Mouse (HEK293, His) Serine protease inhibitor A3N; serpin A3N; serpina3n; Spi2	Mouse	HEK293
	The serpin A3N protein is ubiquitously found in a variety of tissues, showing elevated expression in the brain, heart, liver, lung, spleen, testis, and thymus, implying a variety of physiological functions.In contrast, it shows lower expression in bone marrow, kidney, and skeletal muscle, suggesting a tissue-specific pattern of regulation.Serpin A3N Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A3N protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71841

	Serpin A3N Protein, Mouse (P.pastoris, His) serpina3n; Spi2; Serine protease inhibitor A3N; serpin A3N	Mouse	P. pastoris
	The serpin A3N protein is ubiquitously found in a variety of tissues, showing elevated expression in the brain, heart, liver, lung, spleen, testis, and thymus, implying a variety of physiological functions.In contrast, it shows lower expression in bone marrow, kidney, and skeletal muscle, suggesting a tissue-specific pattern of regulation.Serpin A3N Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Serpin A3N protein, expressed by P.pastoris , with N-6*His labeled tag.

HY-P73526

	Serpin G1 Protein, Human (HEK293, His) C1IN; C1INH; serpinG1; serpin G1; Plasma protease C1 inhibitor	Human	HEK293
	Serpin G1, also known as C1 inhibitor, controls C1 complex activation by forming a proteolytically inactive complex with C1r or C1s proteases. Their interactions regulate physiological pathways such as complement activation, coagulation, fibrinolysis, and kinin production. Serpin G1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin G1 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P73654

	Serpin G1 Protein, Rat (HEK293, His) C1IN; C1INH; serpinG1; serpin G1; Plasma protease C1 inhibitor	Rat	HEK293
	Serpin G1 protein binds complement and inhibits serine-type endopeptidases. It is located in the extracellular space and is involved in aging. Serpin G1 Protein, Rat (HEK293, His) is the recombinant rat-derived Serpin G1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74558

	Serpin A3N Protein, Rat (HEK293, His) serpina3n; Spi2; Serine protease inhibitor A3N; serpin A3N	Rat	HEK293
	The Serpin A3N Protein, belonging to the serpin family, is predominantly expressed in the liver, where it regulates protease activity.As a serine protease inhibitor, Serpin A3N plays a crucial role in modulating enzymatic processes within the liver, highlighting its significance in hepatic functions and maintaining the balance of proteolytic activities in this vital organ.Serpin A3N Protein, Rat (HEK293, His) is the recombinant rat-derived Serpin A3N protein, expressed by HEK293 , with C-His labeled tag.

HY-P76639

	Serpin A10 Protein, Mouse (HEK293, His) Protein Z-Dependent Protease Inhibitor; PZ-Fependent Protease Inhibitor; PZI; serpin A10; serpinA10; ZPI	Mouse	HEK293
	Serpin A10 Protein, an inhibitor, regulates by inhibiting the activity of coagulation protease factor Xa in the presence of PROZ, calcium, and phospholipids. It also shows inhibitory effects on factor XIa even without cofactors, highlighting its versatility in modulating key components of the coagulation cascade. Serpin A10 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A10 protein, expressed by HEK293 , with C-His labeled tag.

HY-P7491

	Serpin A1a Protein, Mouse (HEK293, His) rMuAlpha-1-antitrypsin 1-1, His; serpin A1a; Alpha-1-antitrypsin 1-1	Mouse	HEK293
	Alpha-1 protease inhibitor 1 Protein, Mouse (HEK293, His) is a mouse recombinant Serpin A1a with a His tag at the C-terminus. Alpha-1 protease inhibitor 1 Protein, Mouse (HEK293, His) is produced by Mammalian expression system.

HY-P71293

	Serpin D1 Protein, Mouse (HEK293, His) Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; serpin D1	Mouse	HEK293
	Serpin D1 is a thrombin inhibitor that is activated by glycosaminoglycans such as heparin or dermatan sulfate. In the presence of dermatan sulfate, HC-II surpasses antithrombin III (AT) as the primary thrombin inhibitor. Serpin D1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin D1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71306

	Serpin B9 Protein, Human (HEK293, His) Cytoplasmic antiproteinase 3; Peptidase inhibitor 9; CAP3; PI-9; serpin B9	Human	HEK293
	The Serpin B9 Protein, a member of the serpin family, crucially regulates immune responses by specifically inhibiting granzyme B, a protease involved in immune cell-mediated apoptosis. Acting as a potent inhibitor, Serpin B9 modulates granzyme B's cytotoxic activity, fine-tuning immune responses and preventing unwarranted cell death, emphasizing its significance in maintaining immune balance. Serpin B9 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B9 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71133

	Serpin E1 Protein, Mouse (HEK293, His) 1 Publications Verification Plasminogen activator inhibitor 1; Endothelial plasminogen activator inhibitor; serpin E1; Mr1; Pai1; Planh1	Mouse	HEK293
	Serpin E1 protein is a serine protease inhibitor that regulates TMPRSS7 and is a major inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU).It can significantly downregulate fibrinolysis and control thrombus degradation.Serpin E1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin E1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71143

	Serpin A4 Protein, Human (HEK293, His) Kallistatin; Kallikrein Inhibitor; Peptidase Inhibitor 4; PI-4; serpin A4; serpinA4; KST; PI4	Human	HEK293
	Serpin A4 Protein inhibits tissue kallikrein's amidolytic and kininogenase activities by forming a heat- and SDS-stable equimolar complex with the enzyme. Tissue kallikrein concurrently cleaves the reactive site of Serpin A4, producing a small C-terminal fragment. The protein, existing as a monomer and occasionally forming homodimers, demonstrates its regulatory role in modulating tissue kallikrein-mediated enzymatic activities. Serpin A4 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A4 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70498

	Serpin F1 Protein, Human (HEK293, His) Pigment Epithelium-Derived Factor; PEDF; Cell Proliferation-Inducing Gene 35 Protein; EPC-1; serpin F1; serpinF1; PEDF	Human	HEK293
	Serpin F1 protein, a neurotrophic factor, crucially promotes extensive neuronal differentiation in retinoblastoma cells and serves as a potent inhibitor of angiogenesis. Unlike active serpins, Serpin F1 does not undergo the typical S (stressed) to R (relaxed) conformational transition, lacking serine protease inhibitory activity. It also interacts with PNPLA2, enhancing the phospholipase A2 activity of PNPLA2. Serpin F1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin F1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71054

	Serpin A3 Protein, Human (K267R, HEK293, His) Alpha-1-Antichymotrypsin; ACT; Cell Growth-Inhibiting Gene 24/25 Protein; serpin A3; serpinA3; AACT	Human	HEK293
	Serpin A3 Proteinas, with unclear physiological function, inhibits neutrophil cathepsin G and mast cell chymase, involved in angiotensin-1 to angiotensin-2 conversion. Serpin A3 also interacts with DNAJC1. Serpin A3 Protein, Human (K267R, HEK293, His) is the recombinant human-derived Serpin A3 protein, expressed by HEK293 , with C-6*His labeled tag and K267R mutation.

HY-P70970

	Serpin B6 Protein, Human (Trx-His) serpin B6; Cytoplasmic Antiproteinase; CAP; Peptidase Inhibitor 6; PI-6; Placental Thrombin Inhibitor; serpinB6; PI6; PTI	Human	E. coli
	Serpin B6 protein acts as a potential modulator of serine proteases in the brain or blood. It inhibits cathepsin G, kallikrein 8, and thrombin, suggesting a role in protease regulation. Serpin B6 Protein, Human (Trx-His) is the recombinant human-derived Serpin B6 protein, expressed by E. coli , with N-Trx, N-6*His labeled tag.

HY-P71077

	Serpin E1 Protein, Human (HEK293, His) 1 Publications Verification Plasminogen Activator Inhibitor 1; PAI; PAI-1; Endothelial Plasminogen Activator Inhibitor; serpin E1; serpinE1; PAI1; PLANH1	Human	HEK293
	Serpin E1 is a serine protease inhibitor that regulates various cellular processes by inhibiting TMPRSS7, tissue-type plasminogen activator (PLAT), and urokinase-type plasminogen activator (PLAU). During fibrinolysis, it downregulates PLAT to control thrombus degradation and acts as a PLAU inhibitor to regulate cell adhesion. Serpin E1 Protein, Human (HEK293, His) is the recombinant human-derived Serpin E1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70498A

	Serpin F1 Protein, Human (HEK293, N-His) Pigment Epithelium-Derived Factor; PEDF; Cell Proliferation-Inducing Gene 35 Protein; EPC-1; serpin F1; serpinF1; PEDF	Human	HEK293
	Serpin F1 protein, a neurotrophic factor, crucially promotes extensive neuronal differentiation in retinoblastoma cells and serves as a potent inhibitor of angiogenesis. Unlike active serpins, Serpin F1 does not undergo the typical S (stressed) to R (relaxed) conformational transition, lacking serine protease inhibitory activity. It also interacts with PNPLA2, enhancing the phospholipase A2 activity of PNPLA2. Serpin F1 Protein, Human (HEK293, N-His) is the recombinant human-derived Serpin F1 protein, expressed by HEK293 , with N-6*His labeled tag.

HY-P76640

	Serpin B6 Protein, Human (sf9, His) serpin B6; Cytoplasmic Antiproteinase; CAP; Peptidase Inhibitor 6; PI-6; Placental Thrombin Inhibitor; serpinB6; PI6; PTI	Human	Sf9 insect cells
	Serpin B6 protein acts as a potential modulator of serine proteases in the brain or blood. It inhibits cathepsin G, kallikrein 8, and thrombin, suggesting a role in protease regulation. Serpin B6 Protein, Human (sf9, His) is the recombinant human-derived Serpin B6 protein, expressed by Sf9 insect cells , with N-His labeled tag.

HY-P71297

	Serpin G1 Protein, Mouse (HEK293, His) serpin G1; Plasma protease C1 inhibitor; C1 Inh; C1 esterase inhibitor; C1-inhibiting factor; serping1; C1nh	Mouse	HEK293
	Serpin G1 protein, also known as C1 inhibitor, regulates complement activation, coagulation, fibrinolysis, and kinin production. It forms an inactive complex with C1r or C1s protease and controls C1 complex activation. Serpin G1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin G1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72055

	Serpin A5 Protein, Mouse (sf9, His) serpina5; Pci; Plasma serine protease inhibitor; Plasminogen activator inhibitor 3; PAI-3; PAI3; Protein C inhibitor; PCI; serpin A5	Mouse	Sf9 insect cells
	Serpin A5 protein is a heparin-dependent serine protease inhibitor that controls proteolytic activity in body fluids. It binds irreversibly to the serine activation site, inactivating serine proteases and regulating intravascular and extravascular proteolysis. Serpin A5 Protein, Mouse (sf9, His) is the recombinant mouse-derived Serpin A5 protein, expressed by sf9 insect cells , with N-10*His labeled tag.

HY-P73657

	Serpin A6 Protein, Mouse (HEK293, His) Corticosteroid-binding globulin; CBG; Transcortin; serpinA6	Mouse	HEK293
	Serpin A6 Protein serves as the primary transport protein for glucocorticoids and progestins in the blood of nearly all vertebrate species. Serpin A6 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A6 protein, expressed by HEK293 , with C-His labeled tag.

HY-P73658

	Serpin A6 Protein, Human (HEK293, His) Corticosteroid-binding globulin; CBG; Transcortin; serpinA6	Human	HEK293
	Serpin A6 Protein functions as a vital transport protein, facilitating the transport of glucocorticoids and progestins in the bloodstream across various vertebrate species. Serpin A6 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A6 protein, expressed by HEK293 , with C-His labeled tag.

HY-P7542

	Serpin A1 Protein, Human (HEK293, His) rHuserpin A1/alpha-1-Antitrypsin, His; Alpha-1-Antitrypsin; Alpha-1 Protease Inhibitor; Alpha-1-Antiproteinase; serpin A1; serpinA1; AAT; PI	Human	HEK293
	Serpin A1 Protein, Human (HEK293, His) produced in HEK293 cells is a mouse recombinant Serpin A1a with a His tag at the C-terminus. Alpha-1 Antitrypsin Exerts a hepatoprotective effect on immune-mediated hepatitis and acetaminophen-induced liver injury.

HY-P71039

	Serpin I2 Protein, Human (HEK293, His) serpinI2; serpin I2; Myoepithelium-derived serine protease inhibitor; Pancreas-specific protein TSA2004; Peptidase inhibitor 14; PI-14; MEPI; PI14	Human	HEK293
	Serpin I2 Protein, is a member of the serpin (serine protease inhibitor) superfamily. Serpin I2 (pancpin) is an inhibitory serpin targeting pancreatic elastase and chymotrypsin. Serpin I2 is downregulated in pancreatic and breast cancer, and associated with acinar cell apoptosis and pancreatic insufficiency when absent in mice. Serpin I2 is associated with refractive error and has the potential for further investigations of the genetic susceptibility to myopia research. Serpin I2 Protein, Human (HEK293, His) is the recombinant human-derived Serpin I2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71142

	Serpin B3 Protein, Human (HEK293, His) serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 3; Squamous cell carcinoma antigen 1; T4-A; SCCA1	Human	HEK293
	The Serpin B3 protein exhibits versatility in cellular regulation and may act as a papain-like cysteine protease inhibitor to modulate immune responses against tumor cells. Its dual role extends to inhibiting UV-induced apoptosis by inhibiting c-Jun NH(2)-terminal kinase (JNK1) activity, suggesting that Serpin B3 is involved in the stress response. Serpin B3 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B3 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73659

	Serpin A6 Protein, Human (Biotinylated, HEK293, His-Avi) Corticosteroid-binding globulin; CBG; Transcortin; serpinA6	Human	HEK293
	Serpin A6 Protein functions as a vital transport protein, facilitating the transport of glucocorticoids and progestins in the bloodstream across various vertebrate species. Serpin A6 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Serpin A6 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P70975

	Serpin A5 Protein, Human (HEK293, His) 2 Publications Verification Plasma Serine Protease Inhibitor; Acrosomal Serine Protease Inhibitor; Plasminogen Activator Inhibitor 3; PAI-3; PAI3; Protein C Inhibitor; PCI; serpin A5; serpinA5; PCI; PLANH3; PROCI	Human	HEK293
	Plasma serine protease inhibitor (SERPINA5) is a glycoproteins that inhibit serine proteases. SERPINA5 is involved in the regulation of intravascular and extravascular proteolytic activities, controls the sperm motility and fertilization and protect components of the genital tract. SERPINA5 also inhibits urinary-type plasminogen activator-dependent tumor cell invasion and metastasis. Serpin A5 Protein, Human (HEK293, His) is the recombinant human-derived Serpin A5 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71085

	Serpin E2 Protein, Human (HEK293, His) Glia-derived Nexin; GDN; Peptidase inhibitor 7; PI-7; Protease nexin 1; PN-1; Protease nexin I; serpin E2; serpinE2; PI7; PN1	Human	HEK293
	Serpin E2 is a serine protease inhibitor that inhibits thrombin, trypsin, and urokinase. Its unique role in promoting neurite extension involves specific inhibition of thrombin activity. Serpin E2 Protein, Human (HEK293, His) is the recombinant human-derived Serpin E2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P77196

	SERPINB10 Protein, Mouse (sf9, His) serpin B10; Bomapin; Peptidase inhibitor 10; PI-10	Mouse	Sf9 insect cells
	SERPINB10 is an important protease inhibitor that may regulate protease activity in hematopoiesis and TNF-induced apoptosis. SERPINB10 acts in both the cytoplasm and the nucleus, demonstrating versatility in influencing key cellular processes. SERPINB10 Protein, Mouse (sf9, His) is the recombinant mouse-derived SERPINB10 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P77195

	Serpin A3C Protein, Mouse (HEK293, His) Serine protease inhibitor A3C; Kallikrein-binding protein; KBP; Klkbp	Mouse	HEK293
	Serpin A3C Protein, with its reactive center loop (RCL), guides interactions with target proteases.Binding leads to protease cleavage at the RCL, forming a stable serpin-protease complex, inactivating the protease.Variability in Serpin A3C's RCL sequences among Serpina3 paralogs may influence the specificity of target protease interactions, showcasing the protein's adaptability.Serpin A3C Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin A3C protein, expressed by HEK293 , with C-His labeled tag.

HY-P71294

	Serpin E2 Protein, Mouse (HEK293, His) Glia-derived nexin; GDN; Peptidase inhibitor 7; PI-7; Protease nexin 1; PN-1; Protease nexin I; Serine protease-inhibitor 4; serpin E2; Pi7; Pn1; Spi4	Mouse	HEK293
	Serpin E2, a serine protease inhibitor, inhibits thrombin, trypsin, and urokinase, with a notable role in promoting neurite extension by specifically inhibiting thrombin.Its ability to bind heparin underscores interactions with glycosaminoglycans.The multifaceted inhibitory functions of Serpin E2 highlight its significance in regulating serine protease activities and potential impact on cellular processes, particularly in neurodevelopment.Serpin E2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Serpin E2 protein, expressed by HEK293 , with C-10*His labeled tag.

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HY-P82352

	Angiotensinogen Antibody (YA2097) Angiotensinogen; serpin A8; AGT; serpinA8; Des-Asp[1]-angiotensin II; Serine (or cysteine) proteinase inhibitor	WB, IHC-P, IP	Mouse
	Angiotensinogen Antibody (YA2097) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2097), targeting Angiotensinogen, with a predicted molecular weight of 52 kDa (observed band size: 52 kDa). Angiotensinogen Antibody (YA2097) can be used for WB, IHC-P, IP experiment in mouse background.

HY-P81377

	alpha 1-Antitrypsin Antibody (YA1122) serpinA1; AAT; PI; Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; serpin A1	IHC-P	Human
	alpha 1-Antitrypsin Antibody (YA1122) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1122), targeting alpha 1-Antitrypsin. alpha 1-Antitrypsin Antibody (YA1122) can be used for IHC-P experiment in human background.

HY-P81779

	PAI1 Antibody (YA1524) serpinE1; PAI1; PLANH1; Plasminogen activator inhibitor 1; PAI; PAI-1; Endothelial plasminogen activator inhibitor; serpin E1	WB	Human, Mouse
	PAI1 Antibody (YA1524) is a non-conjugated IgG antibody, targeting PAI1, with a predicted molecular weight of 45 kDa (observed band size: 45 kDa). PAI1 Antibody (YA1524) can be used for WB experiment in human, mouse background.

HY-P82235

	SERPING1 Antibody (YA1980) serpinG1; C1IN; C1NH; Plasma protease C1 inhibitor; C1 Inh; C1Inh; C1 esterase inhibitor; C1-inhibiting factor; serpin G1	WB, IP	Human, Mouse, Rat
	SERPING1 Antibody (YA1980) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1980), targeting SERPING1, with a predicted molecular weight of 55 kDa (observed band size: 100 kDa). SERPING1 Antibody (YA1980) can be used for WB, IP experiment in human, mouse, rat background.

HY-P85030

	AGT Antibody (YA4722) AGT; serpinA8; Angiotensinogen; serpin A8	WB, ELISA	Human

HY-P83607

	Antithrombin III Antibody (YA3352) Antithrombin; Antithrombin III; AT 3; AT III; AT3; AT3D; ATIII; Heparin cofactor I; serpin C1; serpin family C member 1; serpinC1; THPH7	WB, ICC/IF	Human
	Antithrombin III Antibody (YA3352) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3352), targeting Antithrombin III, with a predicted molecular weight of 53 kDa (observed band size: 53 kDa). Antithrombin III Antibody (YA3352) can be used for WB, ICC/IF experiment in human background.

HY-P85847

	Maspin Antibody (YA5539) serpinB5; PI5; serpin B5; Maspin; Peptidase inhibitor 5; PI-5	IHC-P, WB, ICC/IF, ELISA	Human

HY-P85025

	AAT Antibody (YA4717) serpinA1; AAT; PI; Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; serpin A1	WB, ELISA	Human, Mouse

HY-P81358

	AACT Antibody (YA1103) serpinA3; AACT; GIG24; GIG25; Alpha-1-antichymotrypsin; ACT; Cell growth-inhibiting gene 24/25 protein; serpin A3	IHC-P	Human
	AACT Antibody (YA1103) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1103), targeting AACT. AACT Antibody (YA1103) can be used for IHC-P experiment in human background.

HY-P81942

	PEDF Antibody (YA1687) serpinF1; PEDF; PIG35; Pigment epithelium-derived factor; PEDF; Cell proliferation-inducing gene 35 protein; EPC-1; serpin F1	WB, FC	Human
	PEDF Antibody (YA1687) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1687), targeting PEDF, with a predicted molecular weight of 46 kDa (observed band size: 46 kDa). PEDF Antibody (YA1687) can be used for WB, FC experiment in human background.

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