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stabilizers

" in MedChemExpress (MCE) Product Catalog:

129

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40

Biochemical Assay Reagents

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6

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108285

    Others Inflammation/Immunology
    (Rac)-Telmesteine is a protease inhibitor and is thus a suitable enzyme stabilizer extracted from patent WO 2017220302 A1, compound II-1. (Rac)-Telmesteine can be used as an enzyme stabilizer in protease-containing detergents and cleaning agents .
    (Rac)-Telmesteine
  • HY-153767

    MDM-2/p53 Cancer
    PK095 is a p53 mutant stabilizer. PK095 can be used for research of cancer .
    PK095
  • HY-109027

    N91115

    GSNOR CFTR Inflammation/Immunology
    Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor. Cavosonstat is a CFTR stabilizer, and can be used for cystic fibrosis research .
    Cavosonstat
  • HY-156125

    Estrogen Receptor/ERR Others
    14-3-3σ/ERα stabilizer-1 (Compound 181) is a covalent 14-3-3σ/ERα stabilizer. 14-3-3σ/ERα stabilizer-1 can be used for research of molecular glues .
    14-3-3σ/ERα stabilizer-1
  • HY-145890

    Others Inflammation/Immunology
    LC kinetic stabilizer-2 is a potent  amyloidogenic immunoglobulin light chain (LC) kinetic stabilizer with an EC50 of 24 nM .
    LC kinetic stabilizer-2
  • HY-Y0102

    2-Mercaptobenzoic acid

    Biochemical Assay Reagents Others
    Thiosalicylic acid (2-Mercaptobenzoic acid) is a stabilizer that can be used in the synthesis of metal nanoparticles. Thiosalicylic acid is a biomaterial or organic compound that can be used in life science research .
    Thiosalicylic acid
  • HY-W115798

    Magnesium citrate tribasic nonahydrate, 99%

    Biochemical Assay Reagents Others
    Trimagnesium dicitrate nonahydrate, 99% (Magnesium citrate tribasic nonahydrate, 99%) is an orally active magnesium salt of citric acid in the nonahydrate form. Trimagnesium dicitrate nonahydrate, 99% used as a stabilizer and anticaking agent in food supplements in solid and chewable forms .
    Trimagnesium dicitrate nonahydrate, 99%
  • HY-113811

    DIXDS; Diproxide

    Others Others
    Diisopropyl xanthogen disulfide (DIXDS) is a superaccelerator for natural rubber and latex, styrene-butadiene rubber and latex, nitrile butadiene rubber and recycled rubber. It can also be used as a neoprene rubber modifier and an insoluble sulfur stabilizer .
    Diisopropyl xanthogen disulfide
  • HY-155206

    5-HT Receptor Neurological Disease
    (+)-OSU6162 is an stabilizer on dopaminergic and serotonergic brain signaling. (+)-OSU6162 is a partial agonist of 5-HT2A receptor. (+)-OSU6162 can be used for neurological research .
    (+)-OSU6162
  • HY-162838

    Others Others
    TCF199 is an allosteric stabilizer that stabilizes the 14-3-3/TAZ peptide interaction, binding to the 14-3-3ζ/E R α peptide and 14-3-3ζ/Chibby peptide. TCF199 has a Kd value of 122 μM for its interaction with 14-3-3/TAZ .
    TCF199
  • HY-153193

    GLP Receptor Metabolic Disease
    LSN3160440 is an allosteric modulator of GLP-1R, which acts as a protein–protein interaction (PPI) stabilizer or molecular glue to assist in the adhesion of inactive GLP-1 (9-36) NH2 on GLP-1R .
    LSN3160440
  • HY-B1619
    Cromolyn
    3 Publications Verification

    Cromoglicic acid

    Others Inflammation/Immunology
    Cromolyn is a mast cell stabilizer. Cromolyn has the potential for the research of bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis .
    Cromolyn
  • HY-16967

    G-quadruplex Cancer
    MM41 is a potent stabilizer of human telomeric and gene promoter DNA quadruplexes. MM41 is potently against the MIA PaCa-2 pancreatic cancer cell line with IC50 value of <10 nM .
    MM41
  • HY-N7059

    Bacterial Infection
    Lactobionic acid is a bionic acid naturally found in the Caspian Sea yogurt and chemically constituted of a gluconic acid bonded to a galactose. Lactobionic acid has antioxidant, antimicrobial, chelating, stabilizer, acidulant, and moisturizing properties .
    Lactobionic acid
  • HY-159063

    Biochemical Assay Reagents Others
    Soy Polysaccharides are biochemical reagents that can be added to beverages, sauces, and dairy products as thickeners, emulsifiers, and dietary fiber ingredients. Soy Polysaccharides are non-toxic, hydrophilic, and biodegradable, allowing for widespread application in various food sectors. Additionally, Soy Polysaccharides serve as effective stabilizers in oil/water emulsions. Even under acidic conditions, Soy Polysaccharides can stabilize β-conglycinin-based emulsions to prevent flocculation .
    Soy Polysaccharides
  • HY-149513

    c-Myc Apoptosis Cancer
    EP12 is a c-Myc inhibitor. EP12 is a c-Myc G4 stabilizer. EP12 induces apoptosis and DNA damage in multiple myeloma cells. EP12 disrupts the nuclear translocation of P65/P50 by interfering with the NF-κB signaling pathway. EP12 inhibits multiple myeloma growth .
    EP12
  • HY-108468

    Cryptochrome Metabolic Disease
    KL001 is a first-in-class cryptochrome (CRY, a flavoproteins that are sensitive to blue light, and is involved in the circadian rhythms of plants and animals) stabilizer which specifically interacts with CRY1 and CRY2. KL001 prevents ubiquitin-dependent degradation of CRY, resulting in lengthening of the circadian period. KL001 has the potential to control fasting hormone-induced gluconeogenesis .
    KL001
  • HY-W250308

    Epsilon-polylysine (MW 3800-4200); ε-Polylysine (MW 3800-4200); ε-PL (MW 3800-4200)

    Bacterial Others
    Epsilon-polylysine is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine is also used as a liposome stabilizer .
    ε-Poly-L-lysine (MW 3800-4200)
  • HY-W250308A

    Epsilon-polylysine hydrochloride (MV 2000-5000); ε-Polylysine hydrochloride (MV 2000-5000); ε-PL hydrochloride (MV 2000-5000)

    Bacterial Infection
    ε-Poly-L-lysine hydrochloride (MV 2000-5000) is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine hydrochloride inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine hydrochloride has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine hydrochloride can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine hydrochloride is also used as a liposome stabilizer .
    ε-Poly-L-lysine hydrochloride (MV 2000-5000)
  • HY-126127

    Others Inflammation/Immunology
    BRL 22321 free base is a stabilizer with similar mast cell stabilizing activity to Cromolyn sodium (HY-B0320A) and also has some smooth muscle relaxant activity. BRL 22321 free base is more potent than Cromolyn sodium (HY-B0320A) in inhibiting rat passive cutaneous and peritoneal anaphylaxis and antigen-induced histamine release from passively sensitized rat peritoneal cells .
    BRL 22321 free base
  • HY-W094474
    Lithium chloride hydrate
    1 Publications Verification

    hydrate/monohydrateortrihydrate

    GSK-3 Apoptosis Infection Neurological Disease
    Lithium chloride hydrate, an orally active mood stabilizer, is a potent virus inhibitor and effective immunomodulatory agent. Lithium chloride hydrate has antidepressant activity by inhibiting GSK3β and promoting neurogenesis. Lithium chloride hydrate alleviates cognition dysfunction and the symptoms of acute mania and depression. Lithium chloride hydrate can also be used for research of virus infection and Alzheimer's disease .
    Lithium chloride hydrate
  • HY-122815

    Fusicoccin A

    Apoptosis Cancer
    Fusicoccin (Fusicoccin A), a fungal pytotoxin, is a stabilizer of specific 14-3-3 protein-protein interactions. Fusicoccin sabilizes H +-ATPase/14-3-3 cmplex in pants, maintaining the enzyme in activated state. Fusicoccin also stabilizes 14-3-3 protein interactions with binding partners containing a C-terminal 14-3-3 recognition motif (a mode 3 motif), such as ERα, GPIbα, TASK3, CTFR, and p53. Fusicoccin induces apoptosis in cancer cells and has anticancer activity .
    Fusicoccin
  • HY-149779

    Calcium Channel Cardiovascular Disease
    RyR2 stabilizer-1 (compound 12a) is a potent RyR2 stabilizer and SERCA2a activator with EC50s of 2.7 μM for RyR2 and 383 nM for SERCA2. RyR2 stabilizer-1 inhibits Ca 2+ leakage from the SR RyR2 while promoting SERCA2 to pump Ca 2+ back to SR, which make RyR2 stabilizer-1 possible to prevent cardiac arrhythmias .
    RyR2 stabilizer-1
  • HY-159658

    Transthyretin (TTR) Metabolic Disease
    TTR stabilizer 1 (compound 1) is a Transthyretin (TTR) stabilizer, with an EC50 of 0.031 μM .
    TTR stabilizer 1
  • HY-145889

    Others Others
    LC kinetic stabilizer-1 (compound 21) is a potent and selective amyloidogenic immunoglobulin light chain kinetic stabilizer with EC50s of 140 and 74.1 nM for WIL-FL * and WIL-FL * T46L/F49Y, respectively. WIL-FL is an amyloidogenic FL LC dimer .
    LC kinetic stabilizer-1
  • HY-159502

    Parasite Infection
    Surlorian is a ryanodine receptor (RyR) stabilizer .
    Surlorian
  • HY-15278
    Epothilone D
    3 Publications Verification

    KOS 862

    Microtubule/Tubulin Fungal Bacterial Antibiotic Infection Cancer
    Epothilone D (KOS 862) is a potent microtubule stabilizer.
    Epothilone D
  • HY-B2233A

    Biochemical Assay Reagents Others
    Calcium phosphorylcholine chloride, 98% is used as a stabilizer or enhancer in experiments.
    Calcium phosphorylcholine chloride, 98%
  • HY-N11067

    Apoptosis Cancer
    Taccalonolide E is a microtubule stabilizer and induces cancer cell apoptosis.
    Taccalonolide E
  • HY-108567

    Biochemical Assay Reagents Others
    Bisphenol A diglycidyl ether, 85% is used as a stabilizer and embedding agent.
    Bisphenol A diglycidyl ether, 85%
  • HY-111297

    Others Cancer
    BMVC4 is a G-quadruplex (G4) stabilizer of the human telomeric sequence d[AG3(T2AG3)3]. Screening by circular dichroism (CD) spectroscopy revealed that BMVC4 is more suitable as the core molecule of G4 stabilizers than BMVC. The results showed that BMVC4-12C and BMVC4-8C3O are better candidates for G4 stabilizers and are worthy of further study. A simple and rapid screening method based on Cu2+-induced G4 unfolding can be used to find better G4 stabilizers for potential anticancer applications. CD results showed that the trivalent cations of 9-substituted BMVC derivatives are more suitable as G4 stabilizers than the divalent cations of BMVC. In addition, by monitoring the disappearance of the 291 nm CD band of human telomeres after Cu2+ addition, it was found that the core molecule of G4 stabilizer BMVC4 has better stability.
    BMVC4
  • HY-145937

    MDM-2/p53 Cancer
    PK9327 is a small-molecule stabilizer targeting cavity-creating p53 cancer mutations.
    PK9327
  • HY-B0538A

    TWT-8152; BMY 26517

    Histamine Receptor Inflammation/Immunology Endocrinology
    Pemirolast potassium (TWT-8152) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.
    Pemirolast potassium
  • HY-13656

    KOS-1803

    Microtubule/Tubulin Cancer
    Isofludelone (KOS-1803) is a potential microtubule stabilizer for the treatment of solid tumors. Isofludelone has antitumor activity .
    Isofludelone
  • HY-Y1175A

    Biochemical Assay Reagents Others
    Calcium acetate monohydrate, ACS, 99% is a monohydrate form of calcium acetate used to precipitate oxalates in solution; it also serves as a stabilizer, buffer, and chelating agent.
    Calcium acetate monohydrate,ACS, 99%
  • HY-135776

    o-BMVC

    G-quadruplex Cancer
    BMVC2 (o-BMVC) is a bisubstitute carbazole derivative of BMVC. BMVC2 is a G-quadruplex (G4) stabilizer .
    BMVC2
  • HY-15595

    G-quadruplex Telomerase Cancer
    360A is a selective stabilizer of G-quadruplex, and also inhibits telomerase activity with an IC50 of 300 nM for telomerase in TRAP-G4 assay.
    360A
  • HY-14270

    U-42585E free acid

    Histamine Receptor Inflammation/Immunology Endocrinology
    Lodoxamide (U-42585E free acid) is an antiallergic compound acting as a mast-cell stabilizer for the treatment of asthma and allergic conjunctivitis.
    Lodoxamide
  • HY-138694

    Antibiotic Infection
    5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities .
    5-Benzyloxygramine
  • HY-15595A
    360A iodide
    2 Publications Verification

    360 A iodide

    G-quadruplex Telomerase Cancer
    360A iodide is a selective stabilizer of G-quadruplex, and also inhibits telomerase activity with an IC50 of 300 nM for telomerase in TRAP-G4 assay.
    360A iodide
  • HY-126899

    Microtubule/Tubulin Cancer
    TPI-287, a blood-brain barrier-permeable microtubule stabilizer, can significantly reduce metastatic colonization of breast cancer in the brain .
    TPI-287
  • HY-17029
    Epothilone B
    5 Publications Verification

    EPO 906; Patupilone

    Microtubule/Tubulin Fungal Apoptosis Antibiotic Bacterial Infection Cancer
    Epothilone B is a microtubule stabilizer with a Ki of 0.71μM. It acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation.
    Epothilone B
  • HY-43747

    Acetobromo-α-D-glucose, contains 1% CaCO3 as stabilizer; Acetobromo-alpha-D-glucose, contains 1% CaCO3 as stabilizer

    Biochemical Assay Reagents Others
    α-Acetobromoglucose, contains 1% CaCO3 as stabilizer is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    α-Acetobromoglucose, contains 1% CaCO3 as stabilizer
  • HY-B1620D

    PVP K25; Polyvidone K25; Povidone K25

    Biochemical Assay Reagents Others
    Polyvinylpyrrolidone K25 is a multifunctional synthetic polymer. Polyvinylpyrrolidone K25 can be used as stabilizer, emulsifier, suspension agent, solubilizer, protective colloid and complexing agent .
    Polyvinylpyrrolidone K25
  • HY-B1620E

    PVP K60; Polyvidone K60; Povidone K60

    Biochemical Assay Reagents Others
    Polyvinylpyrrolidone K60 is a multifunctional synthetic polymer. Polyvinylpyrrolidone K60 can be used as stabilizer, emulsifier, suspension agent, solubilizer, protective colloid and complexing agent .
    Polyvinylpyrrolidone K60
  • HY-15278A

    (16R)-KOS 862

    Others Infection Cancer
    (16R)-Epothilone D is the isomer of Epothilone D (HY-15278), and can be used as an experimental control. Epothilone D (KOS 862) is a potent microtubule stabilizer.
    (16R)-Epothilone D
  • HY-119506
    KL044
    1 Publications Verification

    Cryptochrome Metabolic Disease
    KL044, a stabilizer of the clock protein cryptochrome (CRY) , is a potent chemical probe with a pEC50 value of 7.32, leading to the extension of the circadian period and repression of Per2 activity .
    KL044
  • HY-109165

    AG10

    Transthyretin (TTR) Metabolic Disease Endocrinology
    Acoramidis (AG10) is an orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin). Acoramidis (AG10) is used in the study for transthyretin amyloidosis .
    Acoramidis
  • HY-109165A

    AG10 hydrochloride

    Transthyretin (TTR) Metabolic Disease Endocrinology
    Acoramidis (AG10) hydrochloride is an orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin). Acoramidis (AG10) hydrochloride is used in the study for transthyretin amyloidosis .
    Acoramidis hydrochloride
  • HY-B1068
    Tyloxapol
    3 Publications Verification

    Triton WR1339

    Biochemical Assay Reagents Metabolic Disease
    Tyloxapol (Triton WR1339) is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surface active stabilizer. Tyloxapol (Triton WR1339) is used to induce hyperlipidemia in animals .
    Tyloxapol

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