2. Gene
  3. Maob - monoamine oxidase B Gene

Maob - monoamine oxidase B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MAO-B; 6330414K01Rik

Gene ID: 109731 | Gene type: protein coding

About Maob

Chromosome X: 16,575,521-16,683,605 reverse strand.GRCm39:CM001013.3

This gene has 4 transcripts (splice variants), 333 orthologues, 9 paralogues and is associated with 4 phenotypes. Biased expression in placenta adult (RPKM 125.6), liver adult (RPKM 44.7) and 11 other tissues.

Summary

Predicted to enable flavin adenine dinucleotide binding activity; identical protein binding activity; and primary amine oxidase activity. Predicted to be involved in negative regulation of serotonin secretion; neurotransmitter catabolic process; and positive regulation of dopamine metabolic process. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and Parkinson's disease. Orthologous to human MAOB (Monoamine Oxidase B). [provided by Alliance of Genome Resources, Apr 2022]

Maob Products(1)

mRNA Protein Name
NM_172778.2 NP_766366.2 amine oxidase [flavin-containing] B

Maob Protein Structure

YobN

YobN: COG1231 (5 - 450)

  • 0
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  • 520 a.a.
Protein Preferred Names Protein Names

amine oxidase [flavin-containing] B

monoamine oxidase type B

Related Agents

Approval
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0159 Paeonol 99.98% Unkown
HY-14280 Entacapone Inhibitor 99.97% Yes
HY-14199 Selegiline hydrochloride Inhibitor 99.94% Unkown
HY-A0091A Pargyline Inhibitor 99.77% Unkown
HY-A0091 Pargyline hydrochloride Inhibitor 99.91% Unkown
HY-70057 Safinamide Inhibitor 99.89% Yes
HY-14855B Tedizolid phosphate Inhibitor 99.65% Yes
HY-70057A Safinamide mesylate Inhibitor 99.87% Yes
HY-B1558A Bifemelane hydrochloride Inhibitor 99.86% Unkown
HY-14198 Selegiline Inhibitor / Unkown
HY-14280R Entacapone (Standard) Inhibitor / Unkown
HY-14280A Entacapone sodium salt Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Phase
HY-N0529 Rosmarinic acid 99.70% Phase 4
HY-129388B Pulrodemstat benzenesulfonate Inhibitor 99.12% Phase 2
HY-112623 Vafidemstat Inhibitor 99.53% Phase 2
HY-10399A Ladostigil hydrochloride Inhibitor 99.94% Phase 2
HY-10400 Ladostigil hemitartrate Inhibitor 98.90% Phase 2
HY-10399 Ladostigil Inhibitor / Phase 2
HY-129388 Pulrodemstat Methylbenzenesulfonate Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (123)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W008566 Norharmane Inhibitor 99.46% Unkown
HY-N0918 Desmethoxyyangonin Inhibitor 99.47% Unkown
HY-110130 RN-1 dihydrochloride Inhibitor 99.13% Unkown
HY-19333 OG-L002 Inhibitor 99.81% Unkown
HY-16677A Mofegiline hydrochloride Inhibitor 99.57% Unkown
HY-N7204 4-Hydroxyderricin 99.97% Unkown
HY-E70074 Monoamine oxidase, plasma / Unkown
HY-131036 MAO-IN-M30 dihydrochloride Inhibitor 99.25% Unkown
HY-14201 Lazabemide Inhibitor 99.95% Unkown
HY-100588 VU0364770 Agonist 99.93% Unkown
HY-103164 (E)-8-(3-Chlorostyryl)caffeine 99.00% Unkown
HY-127109 Tisolagiline Inhibitor 99.97% Unkown
HY-156255 MAO-B-IN-25 Inhibitor 99.11% Unkown
HY-N9540 Methyl citrate Inhibitor ≥98.0% Unkown
HY-W001601 Budipine Antagonist 99.41% Unkown
HY-129388A Pulrodemstat Inhibitor / Unkown
HY-119532 Nordeprenyl / Unkown
HY-121072 ASS234 Inhibitor / Unkown
HY-132907 MAO-B-IN-2 Inhibitor 99.05% Unkown
HY-14280S Entacapone-d10 Inhibitor ≥98.0% Unkown
HY-D0004 Azure B Inhibitor 98.13% Unkown
HY-W010130 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone Inhibitor 99.96% Unkown
HY-117173 (Rac)-Rasagiline Inhibitor / Unkown
HY-114915 PSB-1434 Inhibitor 98.05% Unkown
HY-115986 MAO-B-IN-5 Inhibitor / Unkown
HY-115987 MAO-B-IN-6 Inhibitor / Unkown
HY-116097 PSB-1491 Inhibitor / Unkown
HY-117502 SL-25.1188 Inhibitor / Unkown
HY-120419 PF9601N Inhibitor 99.85% Unkown
HY-120826 A2AAR/hMAO-B-IN-1 Inhibitor / Unkown
HY-127109A Tisolagiline methylsulfate Inhibitor / Unkown
HY-130205 Milacemide hydrochloride Inhibitor / Unkown
HY-14202 Lazabemide hydrochloride Inhibitor / Unkown
HY-14203 (R)-Safinamide Inhibitor 99.88% Unkown
HY-143244 Monoamine Oxidase B inhibitor 1 Inhibitor / Unkown
HY-143245 Monoamine Oxidase B inhibitor 2 Inhibitor / Unkown
HY-143329 MAO-B-IN-3 Inhibitor / Unkown
HY-143330 MAO-B-IN-4 Inhibitor / Unkown
HY-143438 2-PAT Inhibitor / Unkown
HY-144673 LSD1-IN-12 Inhibitor / Unkown
HY-144756 LSD1-IN-15 Inhibitor / Unkown
HY-144757 LSD1-IN-16 Inhibitor / Unkown
HY-144758 LSD1-IN-17 Inhibitor / Unkown
HY-144824 Monoamine oxidase/Aromatase-IN-1 Inhibitor / Unkown
HY-145845 HDAC1/MAO-B-IN-1 Inhibitor / Unkown
HY-146149 MAO-B-IN-11 Inhibitor / Unkown
HY-146150 MAO-B-IN-12 Inhibitor / Unkown
HY-146312 AChE/BChE/MAO-B-IN-1 Inhibitor 99.57% Unkown
HY-146314 MAO-B-IN-9 Inhibitor 99.70% Unkown
HY-146347 MAO-B-IN-10 Inhibitor / Unkown
HY-146677 5-HT6R/MAO-B modulator 1 / Unkown
HY-146762 MAO-B-IN-7 Inhibitor / Unkown
HY-146958 MAO-B-IN-8 Inhibitor 98.03% Unkown
HY-147362 MAO-B-IN-14 Inhibitor / Unkown
HY-147953 MAO-B-IN-13 Inhibitor / Unkown
HY-149242 MAO-B-IN-20 Inhibitor / Unkown
HY-149477 IHC3 Inhibitor / Unkown
HY-149527 MAO-B-IN-23 Inhibitor / Unkown
HY-149528 MAO-B-IN-24 Inhibitor / Unkown
HY-149820 MAO-B-IN-22 Inhibitor / Unkown
HY-149978 LSD1-IN-26 / Unkown
HY-149984 MAO-B-IN-21 Inhibitor / Unkown
HY-150563 Neuroinflammatory-IN-2 Inhibitor / Unkown
HY-151094 FTEAA Inhibitor / Unkown
HY-151208 MAO-B-IN-16 Inhibitor / Unkown
HY-151209 MAO-B-IN-15 Inhibitor / Unkown
HY-151210 MAO-B-IN-17 Inhibitor ≥99.0% Unkown
HY-151800 MAO-A/B-IN-2 Inhibitor / Unkown
HY-152109 AChE/MAO-IN-1 Inhibitor / Unkown
HY-152110 AChE/MAO-IN-2 Inhibitor / Unkown
HY-152111 AChE/MAO-B-IN-3 Inhibitor / Unkown
HY-152112 AChE/BChE/MAO-B-IN-2 Inhibitor / Unkown
HY-152113 AChE/BChE/MAO-B-IN-3 Inhibitor / Unkown
HY-152114 AChE/BChE/MAO-B-IN-4 Inhibitor / Unkown
HY-154977 ETAP Inhibitor / Unkown
HY-155330 PZ-1922 / Unkown
HY-155330A PZ-1922 free base / Unkown
HY-156348 MAO-B-IN-26 Inhibitor / Unkown
HY-157087 AChE/MAO-B-IN-4 Inhibitor / Unkown
HY-157089 AChE/MAO-B-IN-5 Inhibitor / Unkown
HY-157517 MAO-B-IN-29 Inhibitor / Unkown
HY-157934 MAO-IN-4 Inhibitor / Unkown
HY-157981 AChE-IN-60 Inhibitor / Unkown
HY-157982 BChE-IN-28 Inhibitor / Unkown
HY-158092 ChEs/MAOs-IN-2 Inhibitor / Unkown
HY-158732 MAO-B-IN-33 Inhibitor / Unkown
HY-159106 MeSeI / Unkown
HY-160002 MAO-B-IN-27 Inhibitor / Unkown
HY-161240 MAO-B-IN-30 Inhibitor 98.53% Unkown
HY-162061 ChEs/MAOs-IN-1 Inhibitor / Unkown
HY-162303 C175-0062 Inhibitor / Unkown
HY-162606 MAO-A/B-IN-3 Inhibitor / Unkown
HY-162760 COMT-IN-1 Inhibitor / Unkown
HY-163322 MAO-A inhibitor 2 Inhibitor / Unkown
HY-163380 CA/MAO-B-IN-1 Inhibitor 98.34% Unkown
HY-163474 MAO-B-IN-32 Inhibitor / Unkown
HY-163879 hMAO-B-IN-9 Inhibitor / Unkown
HY-16731 Sembragiline Inhibitor / Unkown
HY-168590 MAO-B-IN-36 Inhibitor / Unkown
HY-169156 HDAC6-IN-49 Inhibitor / Unkown
HY-70057S1 Safinamide-d4-1 Inhibitor / Unkown
HY-N12134 Methyl piperate Inhibitor / Unkown
HY-N1636 1-Methyl-2-nonyl-4(1H)-quinolone Inhibitor / Unkown
HY-N1638 1-Methyl-2-undecyl-4(1H)-quinolone Inhibitor / Unkown
HY-RS08022 MAOB Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS08023 Maob Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS08024 Maob Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W035384 MAO-B ligand-1 Inhibitor / Unkown
HY-W205529 RO 16-6491 free base / Unkown
HY-W269511 NW-1689 / Unkown
HY-W335927 MAO-B-IN-19 Inhibitor / Unkown
HY-103164A 8-(3-Chlorostyryl)caffeine / Unkown
HY-10399B (S)-Ladostigil Inhibitor / Unkown
HY-105041 Tedizolid phosphate sodium Inhibitor / Unkown
HY-116765 MAO-B-IN-35 / Unkown
HY-123556 SZV-558 Inhibitor / Unkown
HY-123665 PSB-1410 Inhibitor / Unkown
HY-134664 8α-(2-Methylacryloyloxy)-hirsutinolide-13-O-acetate Inhibitor / Unkown
HY-164649 Atibeprone Inhibitor / Unkown
HY-19333A OG-L002 hydrochloride Inhibitor / Unkown
HY-N13041 Acacetin 7-O-(6-O-malonylglucoside) Inhibitor / Unkown
HY-W029600 6,7-Dimethylisatin Inhibitor / Unkown
HY-W792513 WAY-620147 Inhibitor ≥98.0% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Maob NCBI NCBI:4129