2. Gene
  3. CSNK2A1 - casein kinase 2 alpha 1 Gene

CSNK2A1 - casein kinase 2 alpha 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CKII; Cka1; Cka2; CK2A1; OCNDS

Gene ID: 1457 | Gene type: protein coding

About CSNK2A1

Cytogenetic location: 20p13 Genomic coordinates (GRCh38): 20:472,498-543,790 (from NCBI)

This gene has 48 transcripts (splice variants), 209 orthologues, 2 paralogues and is associated with 2 phenotypes. Ubiquitous expression in testis (RPKM 33.5), brain (RPKM 25.8) and 25 other tissues.

Summary

Casein Kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, Apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. Multiple transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Apr 2018]

CSNK2A1 Products(5)

mRNA Protein Name
NM_001362770.2 NP_001349699.1 casein kinase II subunit alpha isoform a
NM_001362771.2 NP_001349700.1 casein kinase II subunit alpha isoform a
NM_001895.4 NP_001886.1 casein kinase II subunit alpha isoform a
NM_177559.3 NP_808227.1 casein kinase II subunit alpha isoform a
NM_177560.3 NP_808228.1 casein kinase II subunit alpha isoform b
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
24013921 GOA
enables kinase activity IDA
IDA: Inferred from direct assay
18548200 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
10094392 GOA
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
12700239 GOA
enables protein serine/threonine kinase activity IGI
IGI: Inferred from genetic interaction
28031292 GOA
enables protein serine/threonine kinase activity IMP
IMP: Inferred from mutant phenotype
11035045 GOA
Biological Process GO Annotation Evidence Reference Source
involved in DNA damage response IDA
IDA: Inferred from direct assay
18411307 GOA
involved in double-strand break repair IDA
IDA: Inferred from direct assay
22325354 GOA
involved in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
16193064 GOA
involved in negative regulation of double-strand break repair via homologous recombination IDA
IDA: Inferred from direct assay
28512243 GOA
involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process IGI
IGI: Inferred from genetic interaction
28031292 GOA
involved in negative regulation of translation IDA
IDA: Inferred from direct assay
30765518 GOA
involved in peptidyl-serine phosphorylation IDA
IDA: Inferred from direct assay
30699359 GOA
involved in peptidyl-threonine phosphorylation IDA
IDA: Inferred from direct assay
15723517 GOA
involved in positive regulation of Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
12700239 GOA
involved in positive regulation of aggrephagy IDA
IDA: Inferred from direct assay
22017874 GOA
involved in positive regulation of cell growth IDA
IDA: Inferred from direct assay
20625391 GOA
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
20625391 GOA
involved in positive regulation of protein catabolic process IDA
IDA: Inferred from direct assay
20625391 GOA
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
18548200 GOA
involved in protein stabilization IDA
IDA: Inferred from direct assay
22184066 GOA
involved in regulation of chromosome separation IMP
IMP: Inferred from mutant phenotype
11704824 GOA
involved in symbiont-mediated disruption of host cell PML body IDA
IDA: Inferred from direct assay
20719947 GOA
Cellular Component GO Annotation Evidence Reference Source
is active in PML body IDA
IDA: Inferred from direct assay
20719947 GOA
part of PcG protein complex IDA
IDA: Inferred from direct assay
21282530 GOA
part of Sin3-type complex IDA
IDA: Inferred from direct assay
17827154 GOA
located in nucleus IDA
IDA: Inferred from direct assay
21282530 GOA
part of protein kinase CK2 complex IDA
IDA: Inferred from direct assay
15723517 GOA
part of protein kinase CK2 complex IPI
IPI: Inferred from physical interaction
22506723 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CSNK2A1 Protein Structure

Pkinase

Pkinase: Protein kinase domain (39 - 324)

  • 0
  • 100
  • 200
  • 300
  • 391 a.a.
Protein Preferred Names Protein Names

casein kinase II subunit alpha

CK2 catalytic subunit alpha

CSNK2A1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
CSNK2A1 P68400 LHX9 Homo sapiens Q9NQ69
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 LHX9 Homo sapiens Q9NQ69
Validated Y2H
32296183
Intra
CSNK2A1 P68400 LHX9 Homo sapiens Q9NQ69
Y2H Array
32296183
Intra
CSNK2A1 P68400 BEND7 Homo sapiens Q8N7W2-2
Y2H Array
32296183
Intra
CSNK2A1 P68400 BEND7 Homo sapiens Q8N7W2-2
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 BEND7 Homo sapiens Q8N7W2-2
Validated Y2H
32296183
Intra
CSNK2A1 P68400 KIF24 Homo sapiens Q5T7B8-2
Validated Y2H
32296183
Intra
CSNK2A1 P68400 KIF24 Homo sapiens Q5T7B8-2
Y2H Array
32296183
Intra
CSNK2A1 P68400 KIF24 Homo sapiens Q5T7B8-2
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 FAM133A Homo sapiens Q8N9E0
Validated Y2H
32296183
Intra
CSNK2A1 P68400 SLC39A7 Homo sapiens Q92504
Anti Tag CoIP
22317921
Intra
CSNK2A1 P68400 SLC39A7 Homo sapiens Q92504
PLA
22317921
Intra
CSNK2A1 P68400 SET Homo sapiens Q01105
Protein Kinase Assay
17309103
Intra
CSNK2A1 P68400 SET Homo sapiens Q01105
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 REL Homo sapiens Q04864-2
Y2H Array
32296183
Intra
CSNK2A1 P68400 REL Homo sapiens Q04864-2
Validated Y2H
32296183
Intra
CSNK2A1 P68400 REL Homo sapiens Q04864-2
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 NFYA Homo sapiens P23511-2
Y2H Array
32296183
Intra
CSNK2A1 P68400 NFYA Homo sapiens P23511-2
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 TEPSIN Homo sapiens Q96N21
Y2H Array
32296183
Intra
CSNK2A1 P68400 TEPSIN Homo sapiens Q96N21
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 TEPSIN Homo sapiens Q96N21
Validated Y2H
32296183
Intra
CSNK2A1 P68400 PIP4K2B Homo sapiens P78356-2
Y2H Array
32296183
Intra
CSNK2A1 P68400 PIP4K2B Homo sapiens P78356-2
Validated Y2H
32296183
Intra
CSNK2A1 P68400 PIP4K2B Homo sapiens P78356-2
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra
CSNK2A1 P68400 ATN1 Homo sapiens Q86V38
Validated Y2H
32296183
Intra
CSNK2A1 P68400 ATN1 Homo sapiens Q86V38
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 ATN1 Homo sapiens Q86V38
Y2H Array
32296183
Intra
CSNK2A1 P68400 ATN1 Homo sapiens Q86V38
Validated Y2H
32814053
Intra
CSNK2A1 P68400 ATN1 Homo sapiens Q86V38
Y2H Pooling
32814053
Intra
CSNK2A1 P68400 ATN1 Homo sapiens Q86V38
Y2H Array
32814053
Intra
CSNK2A1 P68400 GPATCH2L Homo sapiens Q9NWQ4-1
Validated Y2H
32296183
Intra
CSNK2A1 P68400 GPATCH2L Homo sapiens Q9NWQ4-1
Y2H Array
32296183
Intra
CSNK2A1 P68400 GPATCH2L Homo sapiens Q9NWQ4-1
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 FCHO1 Homo sapiens A0A0C3SFZ9
Y2H Array
32296183
Intra
CSNK2A1 P68400 FCHO1 Homo sapiens A0A0C3SFZ9
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 POU6F2 Homo sapiens P78424
Y2H Array
32296183
Intra
CSNK2A1 P68400 POU6F2 Homo sapiens P78424
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 POU6F2 Homo sapiens P78424
Validated Y2H
32296183
Intra
CSNK2A1 P68400 LHX3 Homo sapiens Q9UBR4-2
Y2H Array
32296183
Intra
CSNK2A1 P68400 LHX3 Homo sapiens Q9UBR4-2
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 LHX3 Homo sapiens Q9UBR4-2
Validated Y2H
32296183
Intra
CSNK2A1 P68400 CT45A1 Homo sapiens Q5HYN5
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 CT45A1 Homo sapiens Q5HYN5
Y2H Array
32296183
Intra
CSNK2A1 P68400 CT45A1 Homo sapiens Q5HYN5
Validated Y2H
32296183
Intra
CSNK2A1 P68400 GPATCH2 Homo sapiens Q9NW75-2
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 GPATCH2 Homo sapiens Q9NW75-2
Validated Y2H
32296183
Intra
CSNK2A1 P68400 GPATCH2 Homo sapiens Q9NW75-2
Y2H Array
32296183
Intra
CSNK2A1 P68400 JADE2 Homo sapiens A0A0C4DFT8
Y2H Array
32296183
Intra
CSNK2A1 P68400 JADE2 Homo sapiens A0A0C4DFT8
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 ZNF177 Homo sapiens Q13360-2
Validated Y2H
32296183
Intra
CSNK2A1 P68400 ZNF177 Homo sapiens Q13360-2
Y2H Array
32296183
Intra
CSNK2A1 P68400 ZNF177 Homo sapiens Q13360-2
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 ZSCAN25 Homo sapiens Q6NSZ9-2
Y2H Array
32296183
Intra
CSNK2A1 P68400 ZSCAN25 Homo sapiens Q6NSZ9-2
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
Intra
CSNK2A1 P68400 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
CSNK2A1 P68400 SIRT1 Homo sapiens Q96EB6
Anti Bait CoIP
21968188
Intra
CSNK2A1 P68400 SIRT1 Homo sapiens Q96EB6
In Gel Kinase Assay
19236849
Intra
CSNK2A1 P68400 GSC2 Homo sapiens O15499
Y2H Array
32296183
Intra
CSNK2A1 P68400 GSC2 Homo sapiens O15499
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 RNF111 Homo sapiens Q6ZNA4
Validated Y2H
25416956
Intra
CSNK2A1 P68400 RNF111 Homo sapiens Q6ZNA4
Pull Down
32707033
Intra
CSNK2A1 P68400 RNF111 Homo sapiens Q6ZNA4
Y2H Prey Pooling
25416956
Intra
CSNK2A1 P68400 PHF19 Homo sapiens Q5T6S3
Y2H Array
32296183
Intra
CSNK2A1 P68400 PHF19 Homo sapiens Q5T6S3
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 PHF19 Homo sapiens Q5T6S3
Validated Y2H
32296183
Intra
CSNK2A1 P68400 BMI1 Homo sapiens P35226
Pull Down
21282530
Intra
CSNK2A1 P68400 LTV1 Homo sapiens Q96GA3
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 LTV1 Homo sapiens Q96GA3
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 SURF6 Homo sapiens O75683
TAP
27705803
Intra
CSNK2A1 P68400 SURF6 Homo sapiens O75683
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 MEOX1 Homo sapiens P50221
Y2H Array
32296183
Intra
CSNK2A1 P68400 MEOX1 Homo sapiens P50221
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 PML Homo sapiens P29590
Protein Kinase Assay
16873060
Intra
CSNK2A1 P68400 PAX5 Homo sapiens Q02548
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 PAX5 Homo sapiens Q02548
Validated Y2H
32296183
Intra
CSNK2A1 P68400 PAX5 Homo sapiens Q02548
Y2H Array
32296183
Intra
CSNK2A1 P68400 HDAC2 Homo sapiens Q92769
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 HDAC2 Homo sapiens Q92769
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 HDAC1 Homo sapiens Q13547
Pull Down
32707033
Intra
CSNK2A1 P68400 HDAC1 Homo sapiens Q13547
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 DEK Homo sapiens P35659
Pull Down
32707033
Intra
CSNK2A1 P68400 DEK Homo sapiens P35659
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 DEK Homo sapiens P35659
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 NCL Homo sapiens P19338
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 NCL Homo sapiens P19338
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 CSNK2A2 Homo sapiens P19784
Density Sedimentation
19011756
Intra
CSNK2A1 P68400 CSNK2A2 Homo sapiens P19784
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 CSNK2A2 Homo sapiens P19784
Pull Down
32707033
Intra
CSNK2A1 P68400 CSNK2A2 Homo sapiens P19784
TAP
27705803
Intra
CSNK2A1 P68400 CSNK2A2 Homo sapiens P19784
Anti Tag CoIP
25852190
Intra
CSNK2A1 P68400 CSNK2A2 Homo sapiens P19784
Anti Tag CoIP
25519132
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
Y2H Array
32296183
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
Pull Down
32707033
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
Protein Kinase Assay
26711270
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
Density Sedimentation
19011756
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
X-Ray Diffraction
11574463
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
Protein Kinase Assay
24535599
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
Anti Tag CoIP
36833176
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
BRET
38225382
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
Anti Tag CoIP
25852190
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
TAP
27705803
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
Y2H
10094392
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
Anti Tag CoIP
25519132
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
Anti Bait CoIP
21968188
Intra
CSNK2A1 P68400 CSNK2B Homo sapiens P67870
Pull Down
21282530
Intra
CSNK2A1 P68400 RPS3 Homo sapiens P23396
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 RPS3 Homo sapiens P23396
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 THRAP3 Homo sapiens Q9Y2W1
Pull Down
32707033
Intra
CSNK2A1 P68400 THRAP3 Homo sapiens Q9Y2W1
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 RPS18 Homo sapiens P62269
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 RPS18 Homo sapiens P62269
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 HSP90AB1 Homo sapiens P08238
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 HSP90AB1 Homo sapiens P08238
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 SSRP1 Homo sapiens Q08945
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 SSRP1 Homo sapiens Q08945
Anti Tag CoIP
25852190
Intra
CSNK2A1 P68400 RPLP1 Homo sapiens P05386
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 RPLP1 Homo sapiens P05386
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 EIF3J Homo sapiens O75822
Pull Down
32707033
Intra
CSNK2A1 P68400 EIF3J Homo sapiens O75822
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 EIF3J Homo sapiens O75822
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 EIF3J Homo sapiens O75822
Anti Tag CoIP
33961781
Intra
CSNK2A1 P68400 EIF3J Homo sapiens O75822
Anti Tag CoIP
25852190
Intra
CSNK2A1 P68400 ZNF558 Homo sapiens Q96NG5
Validated Y2H
32296183
Intra
CSNK2A1 P68400 ZNF558 Homo sapiens Q96NG5
Y2H Array
32296183
Intra
CSNK2A1 P68400 ZNF558 Homo sapiens Q96NG5
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 NFYA Homo sapiens P23511
Y2H Prey Pooling
25416956
Intra
CSNK2A1 P68400 HOXC4 Homo sapiens P09017
Y2H Array
32296183
Intra
CSNK2A1 P68400 HOXC4 Homo sapiens P09017
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 RBM39 Homo sapiens Q14498
Validated Y2H
32296183
Intra
CSNK2A1 P68400 PRPF40A Homo sapiens O75400-2
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 SUDS3 Homo sapiens Q9H7L9
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 SUDS3 Homo sapiens Q9H7L9
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 PNN Homo sapiens Q9H307
Pull Down
32707033
Intra
CSNK2A1 P68400 PNN Homo sapiens Q9H307
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 AIP Homo sapiens O00170
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 AIP Homo sapiens O00170
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 EIF2S2 Homo sapiens P20042
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 EIF2S2 Homo sapiens P20042
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 DDX24 Homo sapiens Q9GZR7
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 DDX24 Homo sapiens Q9GZR7
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 DDX24 Homo sapiens Q9GZR7
Pull Down
32707033
Intra
CSNK2A1 P68400 KIF5C Homo sapiens O60282
Anti Bait CoIP
19011756
Intra
CSNK2A1 P68400 KIF5C Homo sapiens O60282
Density Sedimentation
19011756
Intra
CSNK2A1 P68400 KIF5C Homo sapiens O60282
Protein Kinase Assay
19011756
Intra
CSNK2A1 P68400 KIF5C Homo sapiens O60282
Y2H
19011756
Intra
CSNK2A1 P68400 MAF1 Homo sapiens Q9H063
Protein Kinase Assay
21383183
Intra
CSNK2A1 P68400 MAF1 Homo sapiens Q9H063
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 RNF2 Homo sapiens Q99496
Pull Down
32707033
Intra
CSNK2A1 P68400 RNF2 Homo sapiens Q99496
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 RNF2 Homo sapiens Q99496
TAP
27705803
Intra
CSNK2A1 P68400 RNF2 Homo sapiens Q99496
Anti Tag CoIP
33961781
Intra
CSNK2A1 P68400 TRIM41 Homo sapiens Q8WV44
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 TRIM41 Homo sapiens Q8WV44
Y2H Array
32296183
Intra
CSNK2A1 P68400 TRIM41 Homo sapiens Q8WV44
Validated Y2H
32296183
Intra
CSNK2A1 P68400 ZNF440 Homo sapiens Q8IYI8
Validated Y2H
32296183
Intra
CSNK2A1 P68400 ZNF440 Homo sapiens Q8IYI8
Y2H Array
32296183
Intra
CSNK2A1 P68400 ZNF440 Homo sapiens Q8IYI8
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 DVL3 Homo sapiens Q92997
Validated Y2H
32296183
Intra
CSNK2A1 P68400 THAP1 Homo sapiens Q9NVV9
Y2H Array
32296183
Intra
CSNK2A1 P68400 THAP1 Homo sapiens Q9NVV9
Validated Y2H
25416956
Intra
CSNK2A1 P68400 THAP1 Homo sapiens Q9NVV9
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 THAP1 Homo sapiens Q9NVV9
Validated Y2H
32296183
Intra
CSNK2A1 P68400 THAP1 Homo sapiens Q9NVV9
Y2H Array
25416956
Intra
CSNK2A1 P68400 MMTAG2 Homo sapiens Q9BU76
Validated Y2H
32296183
Intra
CSNK2A1 P68400 MMTAG2 Homo sapiens Q9BU76
Pull Down
32707033
Intra
CSNK2A1 P68400 CCDC116 Homo sapiens Q8IYX3
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 CCDC116 Homo sapiens Q8IYX3
Validated Y2H
32296183
Intra
CSNK2A1 P68400 CCDC116 Homo sapiens Q8IYX3
Y2H Array
32296183
Intra
CSNK2A1 P68400 ZNF670 Homo sapiens Q9BS34
Y2H Array
32296183
Intra
CSNK2A1 P68400 ZNF670 Homo sapiens Q9BS34
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 ZNF670 Homo sapiens Q9BS34
Validated Y2H
32296183
Intra
CSNK2A1 P68400 STAC3 Homo sapiens Q96MF2
Y2H Prey Pooling
25416956
Intra
CSNK2A1 P68400 STAC3 Homo sapiens Q96MF2
Validated Y2H
32296183
Intra
CSNK2A1 P68400 STAC3 Homo sapiens Q96MF2
Validated Y2H
25416956
Intra
CSNK2A1 P68400 STAC3 Homo sapiens Q96MF2
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 STAC3 Homo sapiens Q96MF2
Y2H Array
32296183
Intra
CSNK2A1 P68400 PAX6 Homo sapiens P26367
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 PAX6 Homo sapiens P26367
Y2H Array
32296183
Intra
CSNK2A1 P68400 SF3B2 Homo sapiens Q13435
Anti Tag CoIP
35271311
Intra
CSNK2A1 P68400 SF3B2 Homo sapiens Q13435
Protein Kinase Assay
22113938
Intra
CSNK2A1 P68400 KEAP1 Homo sapiens Q14145
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 KEAP1 Homo sapiens Q14145
Validated Y2H
32296183
Intra
CSNK2A1 P68400 KEAP1 Homo sapiens Q14145
Y2H Array
32296183
Intra
CSNK2A1 P68400 LHX8 Homo sapiens Q68G74
Validated Y2H
32296183
Intra
CSNK2A1 P68400 LHX8 Homo sapiens Q68G74
Y2H Array
32296183
Intra
CSNK2A1 P68400 LHX8 Homo sapiens Q68G74
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 TSPYL2 Homo sapiens Q9H2G4
Y2H Array
32296183
Intra
CSNK2A1 P68400 TSPYL2 Homo sapiens Q9H2G4
Anti Tag CoIP
33961781
Intra
CSNK2A1 P68400 TSPYL2 Homo sapiens Q9H2G4
Pull Down
32707033
Intra
CSNK2A1 P68400 TSPYL2 Homo sapiens Q9H2G4
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 TSPYL2 Homo sapiens Q9H2G4
Validated Y2H
32296183
Intra
CSNK2A1 P68400 SNAI2 Homo sapiens O43623
Y2H Prey Pooling
32296183
Intra
CSNK2A1 P68400 SNAI2 Homo sapiens O43623
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant CSNK2A1 Proteins

Cat. No. Product Name Accession Purity
HY-P76263 CSNK2A1 Protein, Human (sf9, GST) P68400-1 (M1-Q391) ≥95%
HY-P700596 CSNK2A1 Protein, Human (His-SUMO) P68400 (R8-N350) ≥95%

CSNK2A1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P83088 CSNK2A1 Antibody (YA2833) WB Human, Mouse, Rat

Related Diseases

Diseases Alias
Okur-Chung Neurodevelopmental Syndrome

OCNDS

Csnk2a1-Related Neurodevelopmental Syndrome
Prostate Stromal Sarcoma

Stromal Sarcoma Of The Prostate
Trichorhinophalangeal Syndrome, Type I

Trichorhinophalangeal Dysplasia Type I

TRPS1

Trichorhinophalangeal Syndrome Type I

Trps I

Trichorhinophalangeal Syndrome Type 1

Type I Trichorhinophalangeal Syndrome

Giedion Syndrome

Trp Syndrome

Tricho-Rhino-Phalangeal Syndrome 1

Trichorhinophalangeal Syndrome, Type Iii
Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon
Connective Tissue Disease

Connective Tissue Diseases

Connective Tissue Disorder

Abnormality Of Connective Tissue

Disorder Of Connective Tissue

Connective Tissue Disorders
Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation
Malaria

Malaria, Susceptibility To

Malaria, Resistance To

Malaria, Cerebral

Cerebral Malaria

Malaria, Severe, Susceptibility To

Malaria, Severe, Resistance To

Malaria, Cerebral, Susceptibility To

Induced Malaria

Malaria, Vivax, Protection Against

Malaria, Severe

Malaria, Cerebral, Reduced Risk Of

Malaria, Protection Against

Resistance To Malaria Due To G6pd Deficiency

Malaria Due To G6pd Deficiency

Malarial Encephalitis

CM

Malaria Cerebral

Susceptibility To Malaria

Acute Pernicious Fever

Aestivo-Autumnal Fever

Aestivo Autumnal Malaria

Chagres Fever

Continued Malaria Fever

Estivo-Autumnal Fever

Estivo-Autumnal Malaria

Estivo-Autumnal Malarial Fever

Falciparum Fever

Malignant Tertian Fever

Malignant Tertian Malaria

Pernicious Intermittent Fever

Pernicious Malaria

Quotidian Malaria

Subtertian Fever

Subtertian Malaria Fever

Subtertian Malignant Tertian Malaria

Tropical Malaria

Algid Malaria

Bilious Haemoglobinuric Fever

Black Water Fever

Blackwater Fever

Malarial Blackwater Fever

Severe Malarial Falciparum

West African Fever

Malarial Haematinuria

Haemoglobinuric Fever

Haemoglobinuric Malaria

Severe Plasmodium Falciparum Malaria

Malarial Haemoglobinuria

Malarial Haematuria

Falciparum Malaria [Malignant Tertian]

Malaria Tropica

Malarial Shock

Chagres Virus Disease

Malignant Malaria

Mtm - [Malignant Tertian Malaria]

Tm -[Malignant Tertian Malaria]

Panama Fever

St - [Subtertian Malaria]

Malarial Quotidian

Benign Tertian Malaria

Tertian Ague

Vivax Fever

Plasmodium Vivax Malaria Nos

Btm - [Benign Tertian Malaria]

Bt - [Benign Tertian Malaria]

Vivax Malaria

Benign Tertian Vivax Malaria

Tertian Malaria

Quartan Malaria

Quartan Ague

Quartan Fever

Plasmodium Malariae Malaria Nos

Quartan Malarial

Malaria By Plasmodium Malariae

Malariae Malaria

Ovale Tertian Malaria

Plasmodium Ovale Fever

Malaria Fever By Plasmodium Ovale

Ovale Malaria

Malaria By Plasmodium Ovale

Malarial Ovale

Marsh Fever

Remittent Congestive Fever

Coastal Fever

Remittent Gastric Fever

Miasmatic Fever

Congestive Remittent Fever

Intermittent Fever

Jungle Fever

Paludism

Cameroon Fever

Ague

Corsican Fever

Intermittent Bilious Fever

Disease Due To Plasmodiidae

Malarial Fever

Plasmodiosis

Remittent Fever

Roman Fever

Malaria Fever Nos

Malaria Nos

Paludal Fever

Clinically Diagnosed Malaria

Clinically Diagnosed Malaria Without Parasitological Confirmation

Congestive Fever

Malarial Cachexia

Marsh Cachexia

Paludal Cachexia

Recurrent Malaria

Remittent Malaria
Dyskeratosis Congenita

Dyskeratosis Congenita Autosomal Dominant

Dc

Dkc

Zinsser-Engman-Cole Syndrome

Dyskeratosis Congenita, Autosomal Dominant

Autosomal Dominant Dyskeratosis Congenita

Dkca

Dyskeratosis Congenita Scoggins Type

Zinsser-Cole-Engman Syndrome

X-Linked Dyskeratosis Congenita

Hoyeraal-Hreidarsson Syndrome
Lissencephaly

Pachygyria

Broad Gyri Of Cerebrum

Large Gyri Of Cerebrum

Macrogyria
Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
Autism Spectrum Disorder

Asd

Autism Spectrum Disorders

Autistic Continuum

Pervasive Developmental Disorder

Pervasive Development Disorder

Autistic Behavior

Autistic Disorder

Autistic

Autistic Disorder Of Childhood Onset

Infantile Autism

Childhood Autism

Kanner Syndrome

Pervasive Developmental Delay Nos

Pervasive Developmental Disorder, Not Otherwise Specified
Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-157478 CSNK2A-IN-1 Inhibitor 98.46% Unkown
HY-RS03251 CSNK2A1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-163783 CSNK2-IN-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CSNK2A1 MGD MGI:88543
Rattus norvegicus CSNK2A1 RGD RGD:621663