1. Gene
  2. MDM2 - MDM2 proto-oncogene Gene

MDM2 - MDM2 proto-oncogene Gene

Homo sapiens

Also known as HDMX; LSKB; hdm2; ACTFS

Gene ID: 4193 | Gene type: protein coding

About MDM2

Cytogenetic location: 12q15 Genomic coordinates (GRCh38): 12:68,808,172-68,850,686 (from NCBI)

This gene has 36 transcripts (splice variants), 253 orthologues, 1 paralogue and is associated with 79 phenotypes. Ubiquitous expression in colon (RPKM 13.6), bone marrow (RPKM 9.8) and 25 other tissues.

Summary

This gene encodes a nuclear-localized E3 ubiquitin Ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]

MDM2 Products(14)

mRNA Protein Name
NM_006878.3
NM_001145340.3 NP_001138812.1 E3 ubiquitin-protein ligase Mdm2 isoform i
NM_006882.3
NM_001278462.2 NP_001265391.1 E3 ubiquitin-protein ligase Mdm2 isoform l
NM_001367990.1 NP_001354919.1 E3 ubiquitin-protein ligase Mdm2 isoform 2
NM_001145339.2 NP_001138811.1 E3 ubiquitin-protein ligase Mdm2 isoform h
XM_047428853.1 XP_047284809.1 E3 ubiquitin-protein ligase Mdm2 isoform X1
NM_002392.6 NP_002383.2 E3 ubiquitin-protein ligase Mdm2 isoform a
NM_006880.2
NM_001145336.1
NM_032739.1
NM_001145337.3 NP_001138809.1 E3 ubiquitin-protein ligase Mdm2 isoform g
NM_006879.3
NM_006881.3
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables 5S rRNA binding IDA
IDA: Inferred from direct assay
24120868 GOA
enables NEDD8 ligase activity IMP
IMP: Inferred from mutant phenotype
18560357 GOA
enables SUMO transferase activity EXP
EXP: Inferred from Experiment
21900752 GOA
enables disordered domain specific binding IPI
IPI: Inferred from physical interaction
12630860 GOA
enables enzyme binding IPI
IPI: Inferred from physical interaction
15577914 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
17159902 GOA
enables ligase activity IDA
IDA: Inferred from direct assay
17142452 GOA
enables p53 binding IPI
IPI: Inferred from physical interaction
9529249 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
7791904 GOA
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
16479015 GOA
enables ribonucleoprotein complex binding IDA
IDA: Inferred from direct assay
24120868 GOA
enables ubiquitin binding IDA
IDA: Inferred from direct assay
29295817 GOA
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
15314173 GOA
enables ubiquitin protein ligase activity IMP
IMP: Inferred from mutant phenotype
16479015 GOA
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
18382127 GOA
enables ubiquitin-protein transferase activity IDA
IDA: Inferred from direct assay
9450543 GOA
enables ubiquitin-protein transferase activity IMP
IMP: Inferred from mutant phenotype
20173098 GOA
enables zinc ion binding IDA
IDA: Inferred from direct assay
10722742 GOA
Biological Process GO Annotation Evidence Reference Source
involved in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest IMP
IMP: Inferred from mutant phenotype
21726810 GOA
involved in amyloid fibril formation IMP
IMP: Inferred from mutant phenotype
12630860 GOA
involved in apoptotic process IDA
IDA: Inferred from direct assay
30879903 GOA
involved in cellular response to actinomycin D IDA
IDA: Inferred from direct assay
15314173 GOA
involved in cellular response to gamma radiation IDA
IDA: Inferred from direct assay
16213212 GOA
involved in cellular response to hypoxia IEP
IEP: Inferred from expression pattern
20810912 GOA
involved in establishment of protein localization IDA
IDA: Inferred from direct assay
10360174 GOA
involved in negative regulation of DNA damage response, signal transduction by p53 class mediator IDA
IDA: Inferred from direct assay
9529249 GOA
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
9271120 GOA
involved in negative regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
16479015 GOA
involved in negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator IMP
IMP: Inferred from mutant phenotype
17310983 GOA
involved in negative regulation of signal transduction by p53 class mediator IDA
IDA: Inferred from direct assay
16173922 GOA
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9271120 GOA
involved in positive regulation of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
17290220 GOA
involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
11278372 GOA
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
29681526 GOA
involved in protein autoubiquitination IMP
IMP: Inferred from mutant phenotype
16479015 GOA
involved in protein destabilization IDA
IDA: Inferred from direct assay
9529249 GOA
involved in protein destabilization IMP
IMP: Inferred from mutant phenotype
16479015 GOA
involved in protein localization to nucleus IDA
IDA: Inferred from direct assay
10360174 GOA
involved in protein ubiquitination IDA
IDA: Inferred from direct assay
9450543 GOA
involved in protein-containing complex assembly IDA
IDA: Inferred from direct assay
10608892 GOA
involved in proteolysis involved in protein catabolic process IMP
IMP: Inferred from mutant phenotype
25417702 GOA
acts upstream of regulation of cell cycle IDA
IDA: Inferred from direct assay
9529249 GOA
involved in regulation of protein catabolic process IDA
IDA: Inferred from direct assay
9153395 GOA
involved in response to antibiotic IEP
IEP: Inferred from expression pattern
20810912 GOA
involved in ubiquitin-dependent protein catabolic process IDA
IDA: Inferred from direct assay
11278372 GOA
involved in ubiquitin-dependent protein catabolic process IGI
IGI: Inferred from genetic interaction
17237821 GOA
acts upstream of or within ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
24506068 GOA
involved in ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
16479015 GOA
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
30879903 GOA
located in cytoplasm IMP
IMP: Inferred from mutant phenotype
15314173 GOA
colocalizes with nuclear body IDA
IDA: Inferred from direct assay
10360174 GOA
located in nucleolus IDA
IDA: Inferred from direct assay
10707090 GOA
located in nucleolus IMP
IMP: Inferred from mutant phenotype
11718560 GOA
located in nucleoplasm IDA
IDA: Inferred from direct assay
10707090 GOA
located in nucleus IDA
IDA: Inferred from direct assay
10360174 GOA
located in nucleus IMP
IMP: Inferred from mutant phenotype
15314173 GOA
part of protein-containing complex IDA
IDA: Inferred from direct assay
9529249 GOA
part of protein-containing complex IMP
IMP: Inferred from mutant phenotype
11718560 GOA
part of transcription repressor complex IPI
IPI: Inferred from physical interaction
8875929 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MDM2 Protein Structure

SWIB

SWIB: SWIB/MDM2 domain (34 - 107)

zf-RanBP

zf-RanBP: Zn-finger in Ran binding protein and others (306 - 333)

zf-C3HC4_3

zf-C3HC4_3: Zinc finger, C3HC4 type (RING finger) (443 - 490)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 497 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase Mdm2

MDM2 oncogene, E3 ubiquitin protein ligase

MDM2 proto-oncogene, E3 ubiquitin protein ligase

Mdm2, p53 E3 ubiquitin protein ligase homolog

Mdm2, transformed 3T3 cell double minute 2, p53 binding protein

double minute 2, human homolog of

p53-binding protein

oncoprotein Mdm2

MDM2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
MDM2 Q00987 FKBP3 Homo sapiens Q00688
Anti Bait CoIP
19166840
Intra
MDM2 Q00987 SET Homo sapiens Q01105
Display Tech
20195357
Intra
MDM2 Q00987 OTUB1 Homo sapiens Q96FW1
Pull Down
22124327
Intra
MDM2 Q00987 RYR2 Homo sapiens Q92736
Display Tech
20195357
Intra
MDM2 Q00987 CSNK1A1 Homo sapiens P48729
Anti Tag CoIP
20708156
Intra
MDM2 Q00987 PPM1D Homo sapiens O15297
Anti Bait CoIP
17936559
Intra
MDM2 Q00987 CSNK1A1 Homo sapiens P48729-2
Pull Down
20708156
Intra
MDM2 Q00987 RNF115 Homo sapiens Q9Y4L5
Phage Display
35044719
Intra
MDM2 Q00987 RNF115 Homo sapiens Q9Y4L5
FPS
35044719
Cross
MDM2 Q00987 P0C6X5-PRO_0000283876 Human coronavirus NL63 P0C6X5-PRO_0000283876
Anti Tag CoIP
25505178
Cross
MDM2 Q00987 P0C6X5-PRO_0000283876 Human coronavirus NL63 P0C6X5-PRO_0000283876
Confocal
25505178
Intra
MDM2 Q00987 JUND Homo sapiens P17535
Display Tech
20195357
Intra
MDM2 Q00987 JUND Homo sapiens P17535
TAP
20195357
Intra
MDM2 Q00987 PML Homo sapiens P29590
Anti Bait CoIP
12915590
Intra
MDM2 Q00987 PML Homo sapiens P29590
CoIP
12915590
Intra
MDM2 Q00987 PML Homo sapiens P29590
Imaging
12915590
Intra
MDM2 Q00987 AKT1 Homo sapiens P31749
Experimental Interac
15527798
Intra
MDM2 Q00987 AKT1 Homo sapiens P31749
PLA
25241761
Intra
MDM2 Q00987 USP7 Homo sapiens Q93009
FPS
34799561
Intra
MDM2 Q00987 USP7 Homo sapiens Q93009
Anti Bait CoIP
18566590
Intra
MDM2 Q00987 USP7 Homo sapiens Q93009
Anti Bait CoIP
17936559
Intra
MDM2 Q00987 USP7 Homo sapiens Q93009
Anti Tag CoIP
16845383
Intra
MDM2 Q00987 PML Homo sapiens P29590-5
Imaging
12915590
Intra
MDM2 Q00987 PML Homo sapiens P29590-5
Anti Bait CoIP
12915590
Intra
MDM2 Q00987 PML Homo sapiens P29590-5
CoIP
12915590
Intra
MDM2 Q00987 HNRNPK Homo sapiens P61978
Anti Bait CoIP
23092970
Intra
MDM2 Q00987 BTRC Homo sapiens Q9Y297
Anti Bait CoIP
20708156
Intra
MDM2 Q00987 BTRC Homo sapiens Q9Y297
Anti Tag CoIP
20708156
Intra
MDM2 Q00987 BTRC Homo sapiens Q9Y297
Pull Down
20708156
Intra
MDM2 Q00987 UBC Homo sapiens P0CG48
Pull Down
17290220
Intra
MDM2 Q00987 NCL Homo sapiens P19338
Far-WB
22103682
Intra
MDM2 Q00987 NCL Homo sapiens P19338
Pull Down
22103682
Intra
MDM2 Q00987 RPS3 Homo sapiens P23396
PLA
19656744
Intra
MDM2 Q00987 RPS3 Homo sapiens P23396
Ubiquitinase Assay
19656744
Intra
MDM2 Q00987 RPS3 Homo sapiens P23396
Pull Down
19656744
Intra
MDM2 Q00987 EEF1A1 Homo sapiens P68104
Pull Down
23260144
Intra
MDM2 Q00987 EEF1A1 Homo sapiens P68104
Anti Bait CoIP
17373842
Intra
MDM2 Q00987 EEF1A1 Homo sapiens P68104
Confocal
17373842
Intra
MDM2 Q00987 S100A6 Homo sapiens P06703
GMS
20591429
Intra
MDM2 Q00987 RPL23 Homo sapiens P62829
Anti Bait CoIP
17110929
Intra
MDM2 Q00987 RPS7 Homo sapiens P62081
Y2H
17310983
Intra
MDM2 Q00987 RPS7 Homo sapiens P62081
Anti Tag CoIP
17310983
Intra
MDM2 Q00987 RPS7 Homo sapiens P62081
Pull Down
17310983
Intra
MDM2 Q00987 RPS7 Homo sapiens P62081
Y2H
21988832
Intra
MDM2 Q00987 RPS7 Homo sapiens P62081
Anti Bait CoIP
17310983
Intra
MDM2 Q00987 RPL11 Homo sapiens P62913
Anti Bait CoIP
17110929
Intra
MDM2 Q00987 RPL11 Homo sapiens P62913
Anti Bait CoIP
21399665
Intra
MDM2 Q00987 RPL11 Homo sapiens P62913
Y2H
21988832
Intra
MDM2 Q00987 RPL11 Homo sapiens P62913
Anti Bait CoIP
17373842
Intra
MDM2 Q00987 RPL11 Homo sapiens P62913
Anti Tag CoIP
19713960
Intra
MDM2 Q00987 RPS27L Homo sapiens Q71UM5
Anti Tag CoIP
21170087
Intra
MDM2 Q00987 RPS27L Homo sapiens Q71UM5
Anti Bait CoIP
21170087
Intra
MDM2 Q00987 PSME3 Homo sapiens P61289
Anti Tag CoIP
18309296
Intra
MDM2 Q00987 PSME3 Homo sapiens P61289
Pull Down
18309296
Intra
MDM2 Q00987 PSME3 Homo sapiens P61289
Anti Bait CoIP
18309296
Intra
MDM2 Q00987 PSME3 Homo sapiens P61289
GMS
18309296
Intra
MDM2 Q00987 RPS27 Homo sapiens P42677
Anti Tag CoIP
21170087
Intra
MDM2 Q00987 RPS27 Homo sapiens P42677
Pull Down
21170087
Intra
MDM2 Q00987 RPS27 Homo sapiens P42677
Anti Bait CoIP
21170087
Intra
MDM2 Q00987 RPL5 Homo sapiens P46777
Anti Bait CoIP
21399665
Intra
MDM2 Q00987 RPL5 Homo sapiens P46777
Anti Bait CoIP
17373842
Intra
MDM2 Q00987 RPL5 Homo sapiens P46777
Anti Bait CoIP
17110929
Intra
MDM2 Q00987 CUL1 Homo sapiens Q13616
Anti Tag CoIP
20708156
Intra
MDM2 Q00987 CUL1 Homo sapiens Q13616
Anti Bait CoIP
20708156
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Anti Bait CoIP
15848166
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Pull Down
18485870
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Anti Bait CoIP
17310983
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
ELISA
17875722
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Anti Bait CoIP
16845383
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Fluorescence Spectr
16432196
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Anti Tag CoIP
19098711
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
NMR
16432196
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
GMS
18309296
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Anti Bait CoIP
18309296
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Anti Bait CoIP
12915590
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Pull Down
17875722
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Pull Down
17139261
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Solution Sedimentation
16432196
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Anti Bait CoIP
17268548
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Anti Bait CoIP
15144954
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Pull Down
18309296
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Pull Down
10196247
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
ITC
16432196
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
SPR
14704432
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Peptide Array
16432196
Intra
MDM2 Q00987 TP53 Homo sapiens P04637
Anti Bait CoIP
18172499
Intra
MDM2 Q00987 RASSF1 Homo sapiens Q9NS23
Anti Bait CoIP
18566590
Intra
MDM2 Q00987 GRK2 Homo sapiens P25098
Anti Bait CoIP
17006543
Intra
MDM2 Q00987 NR0B2 Homo sapiens Q15466
Anti Bait CoIP
22575647
Intra
MDM2 Q00987 NR0B2 Homo sapiens Q15466
Anti Tag CoIP
22575647
Intra
MDM2 Q00987 GORAB Homo sapiens Q5T7V8
Anti Tag CoIP
20598683
Intra
MDM2 Q00987 MDM4 Homo sapiens O15151
Anti Tag CoIP
15604276
Intra
MDM2 Q00987 MDM4 Homo sapiens O15151
CoIP
10608892
Intra
MDM2 Q00987 MDM4 Homo sapiens O15151
Pull Down
22902369
Intra
MDM2 Q00987 MDM4 Homo sapiens O15151
Anti Bait CoIP
18566590
Intra
MDM2 Q00987 MDM4 Homo sapiens O15151
Y2H
10608892
Intra
MDM2 Q00987 PLK1 Homo sapiens P53350
Anti Bait CoIP
19833129
Intra
MDM2 Q00987 PLK1 Homo sapiens P53350
Protein Kinase Assay
19833129
Intra
MDM2 Q00987 RB1 Homo sapiens P06400
Anti Bait CoIP
20871633
Intra
MDM2 Q00987 RB1 Homo sapiens P06400
Pull Down
16374512
Intra
MDM2 Q00987 CASP3 Homo sapiens P42574
Protease Assay
21726810
Intra
MDM2 Q00987 AR Homo sapiens P10275
Anti Bait CoIP
18332867
Intra
MDM2 Q00987 CDKN2A Homo sapiens Q8N726
Anti Bait CoIP
17909018
Intra
MDM2 Q00987 CDKN2A Homo sapiens Q8N726
CoIP
19166854
Intra
MDM2 Q00987 CDKN2A Homo sapiens Q8N726
IF
12740913
Intra
MDM2 Q00987 CDKN2A Homo sapiens Q8N726
Anti Bait CoIP
18583933
Cross
MDM2 Q00987 Npm1 Mus musculus Q61937
Anti Bait CoIP
15144954
Intra
MDM2 Q00987 GNL3 Homo sapiens Q9BVP2
Anti Tag CoIP
21132010
Intra
MDM2 Q00987 ARRB1 Homo sapiens P49407
Anti Tag CoIP
19879840
Intra
MDM2 Q00987 S100A1 Homo sapiens P23297
GMS
20591429
Intra
MDM2 Q00987 GNL3L Homo sapiens Q9NVN8
Anti Tag CoIP
21132010
Intra
MDM2 Q00987 CSNK1E Homo sapiens P49674
Anti Tag CoIP
20708156
Intra
MDM2 Q00987 CSNK1D Homo sapiens P48730
Anti Tag CoIP
20708156
Intra
MDM2 Q00987 CSNK1D Homo sapiens P48730
IF
20708156
Intra
MDM2 Q00987 S100A2 Homo sapiens P29034
GMS
20591429
Intra
MDM2 Q00987 RYBP Homo sapiens Q8N488
Anti Bait CoIP
19098711
Intra
MDM2 Q00987 RYBP Homo sapiens Q8N488
Y2H
19098711
Intra
MDM2 Q00987 RYBP Homo sapiens Q8N488
Anti Tag CoIP
19098711
Intra
MDM2 Q00987 RYBP Homo sapiens Q8N488
Pull Down
19098711
Intra
MDM2 Q00987 DAXX Homo sapiens Q9UER7
Anti Tag CoIP
16845383
Intra
MDM2 Q00987 DAXX Homo sapiens Q9UER7
Anti Bait CoIP
18566590
Intra
MDM2 Q00987 DAXX Homo sapiens Q9UER7
IF
15364927
Intra
MDM2 Q00987 DAXX Homo sapiens Q9UER7
Anti Tag CoIP
18566590
Intra
MDM2 Q00987 DAXX Homo sapiens Q9UER7
Anti Bait CoIP
16845383
Intra
MDM2 Q00987 ESR1 Homo sapiens P03372
Y2H
11178989
Intra
MDM2 Q00987 ESR1 Homo sapiens P03372
Pull Down
11178989
Intra
MDM2 Q00987 NPM1 Homo sapiens P06748
Anti Bait CoIP
22510990
Intra
MDM2 Q00987 DLG4 Homo sapiens P78352
Pull Down
23260144
Cross
MDM2 Q00987 Fkbp3 Mus musculus Q62446
Pull Down
19166840
Intra
MDM2 Q00987 JUN Homo sapiens P05412
Display Tech
20195357
Intra
MDM2 Q00987 JMY Homo sapiens Q8N9B5
Anti Bait CoIP
17170761
Intra
MDM2 Q00987 KIAA1671 Homo sapiens Q9BY89
Phage Display
35044719
Intra
MDM2 Q00987 RRM2B Homo sapiens Q7LG56
Anti Bait CoIP
19015526
Intra
MDM2 Q00987 NUMB Homo sapiens P49757
Anti Bait CoIP
18172499
Intra
MDM2 Q00987 NUMB Homo sapiens P49757
FPS
35044719
Cross
MDM2 Q00987 Arrb2 Rattus norvegicus P29067
FRET
17984062
Cross
MDM2 Q00987 Arrb2 Rattus norvegicus P29067
BRET
17984062
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Malignant Fibrous Histiocytoma

Undifferentiated Pleomorphic Sarcoma

Ups

Fibroxanthosarcoma

Mfh

Malignant Fibrohistiocytic Tumors

Histiocytoma, Malignant Fibrous

Histiocytoma, Fibrous, Malignant

Heart Cancer

Malignant Neoplasm Of Heart

Heart Neoplasm

Cardiac Tumor

Malignant Cardiac Tumor

Tumour Of Heart

Heart Neoplasms

Cardiac Carcinoma

Adult Liposarcoma
Embryonal Rhabdomyosarcoma

Rhabdomyosarcoma, Embryonal

Rhabdomyosarcoma Embryonal

Botryoid Rhabdomyosarcoma

Erms

Spindle Cell Rhabdomyosarcomas

Synovium Cancer

Malignant Tumor Of Synovium

Synovial Neoplasm

Liposarcoma

Lipomatous Cancer

Lipoma Of Spermatic Cord

Spermatic Cord Lipoma

Oligodendroglioma

Oligodendroglial Neoplasm

Oligodendroglial Tumor

Oligodendroglial Tumors

Well Differentiated Oligodendroglioma

Inflammatory Myofibroblastic Tumor

Inflammatory Fibrosarcoma

Gastroesophageal Reflux

Gastroesophageal Reflux Disease

Gerd

GER

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Acid Reflux

Gastresophageal Reflux

Gastro-Esophageal Reflux

Gerd - Gastro-Esophageal Reflux Disease

Chondroid Lipoma
Ischemic Fasciitis

Atypical Decubital Fibroplasia

Retinal Cancer

Malignant Neoplasm Of Retina

Retinal Neoplasms

Malignant Retinal Neoplasm

Malignant Tumor Of Retina

Neoplasm Of Retina

Retinal Tumor

Retinal Neoplasm

Cancer Of The Retina

Malignant Retinal Tumour

Malignant Tumour Of Retina

Primary Malignant Neoplasm Of Retina

Benign Meningioma

Meningioma, Benign

Retinoblastoma

RB

Trilateral Retinoblastoma

RB1

Retinoblastoma, Trilateral

Neuroblastoma Of Retina

Rb - Retinoblastoma

Eye Cancer, Retinoblastoma

Retinal Cancer

Retinal Tumor

Glioma, Retinal

Non-Hereditary Retinoblastoma

Childhood Cancer Retinoblastoma

Malignant Neoplasm Of Retina

Retinal Neoplasms

Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Protection Against

Lung Cancer, Susceptibility To

Adenocarcinoma Of Lung, Somatic

Nonsmall Cell Lung Cancer

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma

Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1

Bone Osteosarcoma

Osteosarcoma Of Bone

Primary Osteosarcoma Of Bone

Osteogenic Sarcoma

Osteosarcoma

OSRC

Osteosarcoma, Somatic

Neoplasms, Bone Tissue

Bone Tissue Neoplasm

Osteoid Sarcoma

Skeletal Sarcoma

Osteosarcoma Of Bone

Bone Sarcoma

Accelerated Tumor Formation

Accelerated Tumor Formation, Susceptibility To

ACTFS

Tumor Formation, Accelerated, Susceptibility To

B-Cell Lymphoma

Lymphoma, B-Cell

B-Cell Lymphomas

B-Cell Lymphocytic Neoplasm

Lymphoma B-Cell

B-Cell Lymphoma Nos

Cellular Myxoid Liposarcoma

Round Cell Liposarcoma

Long Qt Syndrome

Romano-Ward Syndrome

Long Q-T Syndrome

Lqt

Qt Syndrome, Long

Congenital Long Qt Syndrome

Familial Long Qt Syndrome

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Medulloblastoma

MDB

Cpnet

Localized Primitive Neuroectodermal Tumor

Classic Medulloblastoma

Desmoplastic/Nodular Medulloblastoma

Medulloblastoma With Extensive Nodularity

Desmoplastic Medulloblastoma

Medulloblastoma, Somatic

Medulloblastoma, Desmoplastic

Brain Medulloblastoma

Cns Pnet

Infratentorial Primitive Neuroectodermal Tumor

Mben

Medulloblastoma Desmoplastic

Neuroectodermal Tumors, Primitive

Medulloblastomas

Medulloblastoma, With Extensive Nodularity

Medulloblastoma Of Unspecified Site

Medullomyoblastoma Of Unspecified Site

Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer

Bladder Cancer

Urinary Bladder Cancer

Bladder Carcinoma

Urinary Bladder Carcinoma

Bladder Neoplasm

Bladder Tumor

Cancer, Bladder

Malignant Neoplasm Of Urinary Bladder

Carcinoma Of Bladder

Bladder Cancer, Somatic

Tumor Of The Bladder

Carcinoma Of Urinary Bladder

Bladder Carcinoma Urinary

Cancer Of The Urinary Bladder

Cancer, Urinary Bladder

Malignant Bladder Neoplasm

Malignant Bladder Tumor

Neoplasm Of The Bladder

Neoplasm Of The Urinary Bladder

Tumor Of The Urinary Bladder

Urinary Bladder Neoplasm

BLC

Urothelial Carcinoma Of The Bladder

Bladder Tumors

Urinary Bladder Neoplasms

Bladder Cancer Nos

Vesical Cancer Nos

Malignant Neoplasm Of Bladder, Part Unspecified

Malignant Tumour Of Urinary Bladder

Primary Malignant Neoplasm Of Bladder

Melanoma, Cutaneous Malignant 1

Familial Melanoma

Melanoma, Cutaneous Malignant, Susceptibility To, 1

CMM1

Melanoma, Cutaneous Malignant

Cmm

Melanoma, Malignant

Familial Atypical Mole-Malignant Melanoma Syndrome

Fammm

Melanoma, Familial

Mlm

Dysplastic Nevus Syndrome, Hereditary

Dns

B-K Mole Syndrome

Melanoma, Cutaneous Malignant, 1

Malignant Melanoma, Cutaneous

Melanoma, Cutaneous, Malignant, Susceptibility To, Type 1

Dysplastic Nevus Syndrome

Cutaneous Melanoma

Familial Atypical Mole Melanoma Syndrome

Hereditary Melanoma

Lessel-Kubisch Syndrome

LSKB

Aortic Malignant Tumor

Aortic Malignant Neoplasm

Malignant Aortic Neoplasm

Esophageal Cancer

Esophageal Carcinoma

Carcinoma Of Esophagus

Esophageal Squamous Cell Carcinoma, Somatic

Esophageal Carcinoma, Somatic

Esophagus Cancer

Gastric Cardia Adenocarcinoma

Esophageal Neoplasms

Esophageal Cancer, Somatic

Cancer Of Esophagus

Cancer Of Oesophagus

Carcinoma Of Oesophagus

Ca Lower Third Oesophagus

Ca Middle Third Oesophagus

Malignant Neoplasm Of Distal Third Of Esophagus

Malignant Neoplasm Of Lower Third Of Oesophagus

Malignant Neoplasm Of Middle Third Of Oesophagus

Malignant Neoplasm Of Proximal Third Of Esophagus

Malignant Neoplasm Of Upper Third Esophagus

Malignant Tumor Of Abdominal Esophagus

Malignant Tumor Of Distal Third Of Esophagus

Malignant Tumor Of Proximal Third Of Esophagus

Malignant Tumor Of The Middle Third Of The Esophagus

ESCR

Aerodigestive Tract Cancer

Escc

Esophageal Squamous Cell Carcinoma

Cancer, Esophageal

Malignant Neoplasm Of Esophagus

Squamous Cell Carcinoma Of Esophagus

Malignant Neoplasm Of Middle Third Of Esophagus

Lipomatosis, Multiple

Lipoma

Familial Multiple Lipomatosis

Lipomatosis, Familial Multiple

Benign Lipomatous Tumor

Lipomatous Neoplasm

Multiple Lipomatosis

Fml

Lipo

Benign Tumor Of Adipose Tissue

Lipomatous Tumor

Tumor Of Adipose Tissue

Neoplasms, Adipose Tissue

Lipomas

Spindle Cell Liposarcoma
Esophageal Lipoma

Lipoma Of Esophagus

Adenocarcinoma

Adenocarcinomas

Adenoacanthoma Of Unspecified Site

Adenocarcinoid Of Unspecified Site

Adenocarcinoid Tumour Of Unspecified Site

Adenocarcinoma And Carcinoid Combined Of Unspecified Site

Adenocarcinoma Nos

Heart Sarcoma

Cardiac Sarcoma

Sarcoma Of Heart

Progeroid Syndrome
Infiltrating Angiolipoma

Angiolipoma, Infiltrating

Glioblastoma Classical Subtype
Cheilitis
Retroperitoneal Sarcoma
Infiltrating Lipoma

Intramuscular Lipoma

Squamous Cell Carcinoma

Epidermoid Carcinoma

Squamous Cell Cancer

Carcinoma, Squamous Cell

Malignant Squamous Cell Tumor

Squamous Carcinoma

Squamous Cell Epithelioma

Squamous Cell Skin Cancer

Carcinoma Squamous Cell

Neoplasms, Squamous Cell

Squamous Cell Carcinoma - Category

Malignant Squamous Cell Neoplasm

Squamous Cell Carcinoma Of Skin

Brain Cancer

Malignant Neoplasm Of Brain

Adult Brain Tumor

Brain Neoplasms

Brain Neoplasm

Neoplasm Of Brain

Primary Malignant Neoplasm Of Brain

Brain Tumors

Adult Malignant Brain Neoplasm

Brain Neoplasm, Adult

Bt - Brain Tumour

Malignant Brain Tumour

Malignant Primary Brain Neoplasm

Malignant Primary Brain Tumor

Malignant Tumor Of Adult Brain

Malignant Tumor Of Brain

Primary Brain Neoplasm

Primary Brain Tumor

Tumor Of The Brain

Brain Tumor, Adult

Brain Tumor Primary

Malignant Primary Brain Tumors

Primary Brain Tumors

Cancer, Brain

Brain Tumor, Primary

Pleomorphic Liposarcoma

Pls

Liposarcoma Pleomorphic

Liposarcoma, Pleomorphic

Myxoid Liposarcoma

Myxoid/Round Cell Liposarcoma

Liposarcoma, Myxoid

Mrcls

Myxoliposarcoma

MXLIPO

Liposarcoma Myxoid

Liposarcoma

Spindle Cell Sarcoma

Sarcoma

Sarcoma Spindle Cell

Sarcoma, Spindle Cell

Sarcoma - Category

Gliosarcoma

Glioblastoma With Sarcomatous Component

Sarcomatous Glioblastoma

Leiomyosarcoma

Leiomyosarcomas

Dermatofibrosarcoma Protuberans

DFSP

Dermatofibrosarcoma

Giant Cell Fibroblastoma

Metastatic Dermatofibrosarcoma Protuberans

Familial Dermatofibrosarcoma Protuberans

Darier-Ferrand Tumor

Darier-Hoffmann Tumor

Fibrosarcomatous Osteosarcoma

Fibroblastic Osteosarcoma

Fibrosarcomatous Osteogenic Sarcoma

Gastric Liposarcoma

Liposarcoma Of The Stomach

Autonomic Nervous System Neoplasm

Tumor Of Autonomic Nervous System

Well-Differentiated Liposarcoma

Atypical Lipomatous Tumor

Atypical Lipoma

Alt

Wdls

Liposarcoma, Well Differentiated

Pleomorphic Lipoma

Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia

Aase Syndrome

Erythrogenesis Imperfecta

Anemia, Diamond-Blackfan

Aase-Smith Ii Syndrome

Bds

Blackfan-Diamond Anemia

Congenital Prca

Congenital Hypoplastic Anemia

Congenital Hypoplastic Anemia, Blackfan-Diamond Type

Dba

Blackfan - Diamond Syndrome

Chronic Constitutional Pure Red Cell Anaemia

Anemia Diamond Blackfan Type

Anemia Congenital Erythroid Hypoplastic

Aregenerative Anemia Chronic Congenital

Blackfan Diamond Syndrome

Red Cell Aplasia, Pure Hereditary

Aase-Smith Syndrome Ii

Bda

Blackfan Diamond Anemia

Blackfan-Diamond Disease

Blackfan-Diamond Syndrome

Chronic Congenital Agenerative Anemia

Congenital Erythroid Hypoplastic Anemia

Congenital Hypoplastic Anemia Of Blackfan And Diamond

Congenital Pure Red Cell Anemia

Hypoplastic Congenital Anemia

Inherited Erythroblastopenia

Pure Hereditary Red Cell Aplasia

Anemia, Hypoplastic, Congenital

Anemia Hypoplastic Congenital

Fanconi Anemia

Constitutional Aplastic Anemia

Diamond-Blackfan Anemia 1

Aase Smith Syndrome 2

Congenital Red Cell Aplasia

Red Cell Aplasia Of Infants

Pure Red Cell Aplasia Of Infants

Congenital Red Cell Aplastic Anaemia

Congenital Pure Red Cell Anaemia

Congenital Erythroid Hypoplasia

Pearson Marrow-Pancreas Syndrome

Muscle Cancer

Myosarcoma

Malignant Neoplasm Of Muscle

Malignant Tumor Of Muscle

Malignant Tumor Of The Muscle

Muscle Neoplasms

Myomatous Neoplasm

Dyskeratosis Congenita

Dyskeratosis Congenita Autosomal Dominant

Dc

Dkc

Zinsser-Engman-Cole Syndrome

Dyskeratosis Congenita, Autosomal Dominant

Autosomal Dominant Dyskeratosis Congenita

Dkca

Dyskeratosis Congenita Scoggins Type

Zinsser-Cole-Engman Syndrome

X-Linked Dyskeratosis Congenita

Hoyeraal-Hreidarsson Syndrome

Gastrointestinal Stromal Tumor

GIST

Gastrointestinal Stromal Tumors

Gastrointestinal Stromal Sarcoma

Gastrointestinal Stromal Tumor, Familial

Gant

Gastrointestinal Stromal Tumour

Stromal Tumor Of Gastrointestinal Tract

Stromal Tumour Of Gastrointestinal Tract

Gastrointestinal Stromal Neoplasm

Paraganglioma And Gastric Stromal Sarcoma

Plexosarcoma

Esophagus Verrucous Carcinoma

Oesophagus Verrucous Carcinoma

Verrucous Carcinoma Of Esophagus

Verrucous Carcinoma Of Oesophagus

Verrucous Carcinoma Of The Esophagus

Periosteal Osteogenic Sarcoma

Periosteal Osteosarcoma

Parosteal Osteosarcoma

Maxillary Sinus Adenocarcinoma

Adenocarcinoma Of Maxillary Sinus

Adenocarcinoma Of The Maxillary Sinus

Diffuse Large B-Cell Lymphoma

Dlbcl

Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

Large B-Cell Diffuse Lymphoma

Lymphoma, Large B-Cell, Diffuse

Dlbcl - [Diffuse Large B-Cell Lymphoma]

Diffuse Large Beta Cell Lymphoma

Peripheral Nervous System Disease

Peripheral Neuropathy

Peripheral Nerve Disease

Peripheral Nerve Disorders

Neuropathy, Peripheral

Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation

Malignant Pleural Mesothelioma

Malignant Mesothelioma Of Pleura

Pleural Malignant Mesothelioma

Advanced Sleep Phase Syndrome, Familial, 1

Advanced Sleep Phase Syndrome 1

FASPS1

Familial Advanced Sleep Phase Syndrome 1

Sleep Phase Syndrome, Advanced, Familial, Type 1

Telangiectatic Osteogenic Sarcoma

Telangiectatic Osteosarcoma

Bone Sarcoma
Skeletal Muscle Cancer

Malignant Tumor Of Skeletal Muscle

Skeletal Muscle Neoplasm

Transitional Cell Carcinoma

Transitional Cell Neoplasm

Carcinoma, Transitional Cell

Transitional Carcinoma

Transitional Cell Tumor

Urothelial Cell Carcinoma

Carcinoma Transitional Cell

Transitional Cell Carcinoma Of Bladder

Lymphoma, Non-Hodgkin, Familial

Non-Hodgkin Lymphoma

Lymphoma, Non-Hodgkin

NHL

Lymphoma, Non-Hodgkin, Somatic

Lymphoma, Follicular, Somatic

Familial Non-Hodgkin Lymphoma

Lymphoma Non-Hodgkins

Follicular Lymphoma, Somatic

Lymphosarcoma

Non-Hodgkins Lymphoma

Fanconi Anemia, Complementation Group A

Fanconi Anemia

Fanconi Pancytopenia

Fanconi Anemia Complementation Group A

FANCA

Fa

Fanconi Panmyelopathy

Fanconi'S Anemia

Fanconi Anaemia

Fanconi'S Anaemia

Fanconi Hypoplastic Anemia

Estren-Dameshek Variant Of Fanconi Anemia

Estren-Dameshek Variant Of Fanconi Pancytopenia

Fanconi Anemia Estren-Dameshek Variant

Fanconis Anemia

Conventional Osteosarcoma

Intracortical Osteosarcoma

Conventional Central Osteosarcoma

Intracortical Osteogenic Sarcoma

Medullary Osteosarcoma

Colon Leiomyosarcoma

Colonic Leiomyosarcoma

Aplastic Anemia

Aplastic Anemia, Susceptibility To

Anemia Aplastic

Idiopathic Aplastic Anemia

Secondary Aplastic Anemia

Idiopathic Bone Marrow Failure

Aplastic Anemia Idiopathic

AA

Anemia, Aplastic

Aplastic Anemia, Idiopathic

Erythroid Aplasia

Aa - [Aplastic Anaemia]

Haematopoietic Aplasia

Aleukia Haemorrhagica

Anaemia Due To Decreased Red Cell Production

Aplasia Bone Marrow

Aplastic Bone Marrow

Hypoplastic Anaemia Nos

Myeloid Bone Marrow Aplasia

Pancytopenia

Panhaematopenia

Hypoproliferative Anaemia

Medullary Hypoplasia

Red Blood Cells Hypoplastic Anaemia

Panmyelophthisis

Panhemocytopenia

Refractive Hypoproliferative Anaemia

Toxic Anaemia

Toxic Aplastic Anaemia

Aplastic Anaemia Due To Toxic Cause

Idiopathic Aplastic Anaemia Nos

Mixed Liposarcoma

Mixed-Type Liposarcoma

Myxoid/Round Cell Liposarcoma

Glioblastoma

Glioblastoma Multiforme

Gbm

Adult Glioblastoma Multiforme

Grade Iv Adult Astrocytic Tumor

Primary Glioblastoma Multiforme

Spongioblastoma Multiforme

Adult Glioblastoma

Primary Glioblastoma

Thymus Lipoma

Thymolipoma

Heart Leiomyosarcoma

Leiomyosarcoma Of Heart

Cardiac Leiomyosarcoma

Inflammatory Liposarcoma
Extraosseous Osteosarcoma

Extraskeletal Osteosarcoma

Extraskeletal Osteogenic Sarcoma

Mesenchymal Cell Neoplasm

Benign Miscellaneous Mesenchymal Tumor

Mesenchymal Tumor

Mesenchymal Tumors

Diffuse Lipomatosis
Chondrosarcoma

Cartilaginous Cancer

Chondrosarcoma Of Bone

Primary Chondrosarcoma Of The Bone

CHDSA

Li-Fraumeni Syndrome

Sarcoma Family Syndrome Of Li And Fraumeni

Sbla Syndrome

LFS

Li-Fraumeni Familiar Cancer Susceptibility Syndrome

Sarcoma, Breast, Leukaemia And Adrenal Gland Syndrome

Lfs1

Li Fraumeni Syndrome

Sarcoma, Breast, Leukemia, And Adrenal Gland Syndrome

Lfl

Sbla Syndrome Li-Fraumeni-Like Syndrome

Li-Fraumeni Syndrome 1

Lymphoma

Lymphoid Cancer

Lymphomas

Lymphoid Cancers

Lymphoid Neoplasm

Lymphoma Nos

Nhl - [Non-Hodgkin Lymphoma]

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Nos

Non-Hodgkin Malignant Lymphoma Nos

Immune System Organ Benign Neoplasm
Ataxia-Telangiectasia

Ataxia Telangiectasia

Louis-Bar Syndrome

AT

At1

Ataxia-Telangiectasia Syndrome

Ataxia - Telangiectasia Variant

Boder-Sedgwick Syndrome

Louis Bar Syndrome

Cerebello-Oculocutaneous Telangiectasia

Immunodeficiency With Ataxia Telangiectasia

A-T

Ataxia Telangiectasia Syndrome

Atm

Telangiectasia, Cerebello-Oculocutaneous

Ataxia-Telangiectasia Variant

Spindle Cell Lipoma
Breast Cancer

Breast Carcinoma

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Male Breast Cancer

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Connective Tissue Benign Neoplasm

Soft Tissue Neoplasms

Mesenchymal Tissue Neoplasm

Neoplasm Of Soft Tissue

Neoplasm Of Soft Tissues

Soft Tissue Benign Neoplasm

Tumor Of The Soft Tissue

Soft Tissue Neoplasm

Sarcoma, Synovial

Synovial Sarcoma

Synovialosarcoma

Synovial Cell Sarcoma

Sarcoma Synovial

Conventional Lipoma

Classic Type Lipoma

Paratesticular Lipoma
Peripheral Nervous System Neoplasm

Nerve Sheath Neoplasm

Peripheral Nervous System Neoplasms

Neoplasm Of Peripheral Nerve

Tumor Of Pns

Nerve Sheath Neoplasms

Nerve Sheath Tumors

Mediastinal Mesenchymal Tumor

Mediastinal Mesenchymal Tumour

Soft Tissue Tumor Of Mediastinum

Soft Tissue Tumour Of Mediastinum

Chordoma

CHDM

Notochordoma

Notochordal Sarcoma

Chordoma, Susceptibility To

Chordocarcinoma

Chordoepithelioma

Anaplastic Ependymoma

Ependymoma, Anaplastic

Undifferentiated Ependymoma

Childhood Liposarcoma

Pediatric Liposarcoma

Childhood Acute Lymphocytic Leukemia

Childhood Acute Lymphoblastic Leukemia

Childhood All

Pediatric Acute Lymphoblastic Leukemia

Lymphoblastic Leukemia Acute Childhood

Lipoma Of Colon

Colonic Lipoma

Colon Lipoma

Parosteal Osteosarcoma

Juxtacortical Osteosarcoma

Parosteal Osteogenic Sarcoma

Osteosarcoma, Juxtacortical

Peripheral Osteosarcoma

Surface Osteosarcoma

Bone Surface Osteosarcoma

Leukemia, Chronic Lymphocytic

Chronic Lymphocytic Leukemia

B-Cell Chronic Lymphocytic Leukemia

CLL

B-Cell Chronic Lymphoid Leukemia

Chronic Lymphatic Leukemia

Chronic Lymphocytic Leukaemia

Lymphoplasmacytic Leukemia

Small Lymphocytic Lymphoma

Leukemia, Chronic Lymphatic

B-Cell Chronic Lymphocytic Leukaemia

Chronic Lymphatic Leukaemia

Lymphoplasmacytic Leukaemia

B Cell Chronic Lymphocytic Leukemia

Chronic B-Cell Lymphocytic Leukemia

Leukemia, Lymphocytic, Chronic

B-Cll

Chronic Lymphoid Leukemia

Leukemia Lymphocytic Chronic

Lymphoma Small Lymphocytic

Leukemia, Lymphocytic, Chronic, B-Cell

Pancreas Sarcoma

Sarcoma Of Pancreas

Sclerosing Liposarcoma
Pleomorphic Adenoma

Mixed Tumor Of The Salivary Gland

Adenoma Pleomorphic

Adenoma, Pleomorphic

Mixed Salivary Gland Tumor

Mixed Tumor, Not Otherwise Specified

Melanoma, Uveal

Uveal Melanoma

Choroidal Melanoma

Melanoma Of Uvea

Iris Melanoma

Malignant Melanoma Of Choroid

Malignant Melanoma Of Iris

Mantle Cell Lymphoma

Lymphoma, Mantle Cell

Lcm

Mcl

Mantle Zone Lymphoma

Lymphoma Mantle-Cell

Lymphoma, Mantle-Cell

Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse

Malignant Lymphoma - Lymphocytic, Intermediate Differentiation

Diffuse Small Cleaved-Cell Lymphoma

Diffuse Small Cleaved Cell Malignant Lymphoma

Small Cleaved Cell Non-Hodgkin Lymphoma

Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma

Malignant Lymphomatous Polyposis

Malignant Small Cell, Noncleaved, Diffuse Lymphoma

Malignant Undifferentiated Cell, Non-Burkitt Lymphoma

Cleaved Cell Lymphoma

Small Cell Mantle Cell Lymphoma

Small Cleaved Cell Malignant Lymphoma

Rhabdomyosarcoma
Large Intestine Lipoma

Lipoma Of Large Intestine

Colorectal Lipoma

Spermatic Cord Cancer

Malignant Tumor Of Spermatic Cord

Malignant Tumor Of The Spermatic Cord

Spermatic Cord Ca

Malignant Neoplasm Of Spermatic Cord

Chest Wall Lipoma

Lipoma Of The Chest Wall

Lipoma Of Chest Wall

Pancreatic Adenocarcinoma

Adenocarcinoma Of Pancreas

Adenocarcinoma Of The Pancreas

Pancreas Adenocarcinoma

Malignant Exocrine Neoplasm

Primary Pancreatic Adenocarcinoma

Adenocarcinoma Of Islet Cell Of Pancreas

Islet Cell Adenocarcinoma Of Unspecified Site

Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site

Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma

Familial Retinoblastoma

Hereditary Retinoblastoma

Retinoblastoma

Giant Cell Glioblastoma

Monstrocellular Sarcoma

Malignant Peripheral Nerve Sheath Tumor

Mpnst

Malignant Neurilemmoma

Neurofibrosarcoma

Malignant Neurofibroma

Malignant Schwannoma

Neurogenic Sarcoma

Malignant Neoplasm Of The Peripheral Nerve Sheath

Schwannoma, Malignant

Malignant Peripheral Nerve Sheath Tumors

Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Cancer Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary

Pleomorphic Lipoma

Lipoma

Lipoma Pleomorphic

Lipomatosis, Multiple

Acute Promyelocytic Leukemia

Leukemia, Acute Promyelocytic

Acute Myeloblastic Leukemia Type 3

Aml M3

APL

Leukemia, Acute Promyelocytic, Somatic

Aml With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Apml

Acute Myeloblastic Leukemia 3

Acute Myeloid Leukemia With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Acute Myeloblastic Leukaemia Type 3

Acute Myeloid Leukaemia M3

Acute Myeloid Leukemia M3

Acute Promyelocytic Leukaemia

M3 Anll

Myeloid Leukemia, Acute, M3

Leukemia Promyelocytic Acute

Leukemia, Promyelocytic, Acute

Leukemia, Acute, Promyelocytic

Dedifferentiated Liposarcoma

Ddls

Liposarcoma Dedifferentiated

Liposarcoma, Dedifferentiated

Myxofibrosarcoma

Fibromyxosarcoma

Fibromyxoid Sarcoma

Myxoid Malignant Fibrous Histiocytoma

Dermatofibrosarcoma Protuberans, Myxoid

Sarcoma

Connective And Soft Tissue Neoplasm

Tumor Of Soft Tissue And Skeleton

Sarcomas

Sarcoma - Category

Myositis Ossificans

Myisitis Ossificans

Ossification - Muscle

Meningioma, Familial

Meningioma

Familial Meningioma

Meningioma, Familial, Susceptibility To

Meningeal Neoplasm

Meningeal Neoplasms

Meningiomas

Meningioma, Nf2-Related, Somatic

Meningioma, Sis-Related

Meningothelial Cell Tumor

Neoplasm Of The Meninges

Primary Meningeal Tumor

Familial Multiple Meningioma

MNGMA

Meningioma, Benign, No Icd-O Subtype

Intracranial Meningioma

Meningothelial Cell Neoplasm

Supratentorial Meningioma

Primary Neoplasm Of Spinal Meninges

Benign Intracranial Meningioma

Benign Meningioma

Meningeal Tumours

Meningeal Sarcoma Of Unspecified Site

Meningothelial Sarcoma Of Unspecified Site

Kidney Liposarcoma

Liposarcoma Of Kidney

Breast Liposarcoma

Liposarcoma Of The Breast

Endometrial Cancer

Endometrial Carcinoma

Endometrial Neoplasm

Malignant Neoplasm Of Endometrium

Endometrioid Carcinoma

Endometrial Neoplasms

Carcinoma, Endometrioid

Endometrial Cancer, Familial

Endometrial Carcinoma, Somatic

Endometrial Cancer, Susceptibility To

Endometrial Ca

Malignant Endometrial Neoplasm

Neoplasm Of Endometrium

Primary Malignant Neoplasm Of Endometrium

Tumor Of Endometrium

Carcinoma Of The Endometrium

Endometrioid Carcinoma Of Female Reproductive System

ENDMC

Carcinoma Endometrioid

Endometrial Cancers

Cancer, Endometrial

Uterine Corpus Cancer

Glioma
Malignant Inflammatory Fibrous Histiocytoma

Inflammatory Mfh

Xanthosarcoma

Eye Disease

Eye Diseases

Abnormality Of The Eye

Toxoplasma Oculopathy

Liposarcoma Of Bone

Liposarcoma Of The Bone

Wilms Tumor 1

Nephroblastoma

Wilms Tumor

WT1

Wilms' Tumor

Bilateral Wilms Tumor

Wilms Tumor, Type 1

Wilms Tumor, Somatic

Adult Nephroblastoma

Wt1 Disorder

Renal Embryonic Tumor

Adult Kidney Wilms Tumor

Childhood Kidney Wilms Tumor

Nonanaplastic Kidney Wilms Tumor

Leukemia, Acute Myeloid

Acute Myeloid Leukemia

Leukemia, Acute Myelogenous

Acute Myelogenous Leukemia

AML

Leukemia, Acute Myeloid, Susceptibility To

Acute Myeloblastic Leukemia

Leukemia, Acute Myeloid, Reduced Survival In, Somatic

Acute Myeloid Leukaemia

Leukemia, Myelocytic, Acute

Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome

Secondary Aml

Acute Myelocytic Leukemia

Leukemia, Myeloid, Acute

Acute Myeloid Leukemia, Somatic

Leukemia, Acute Myeloid, Somatic

Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic

Acute Myeloblastic Leukaemia

Acute Myelogenous Leukaemia

Aml - Acute Myeloid Leukemia

Acute Myeloid Leukemia With Cebpa Somatic Mutations

Aml With Cebpa Somatic Mutations

Inherited Acute Myeloid Leukemia

Familial Aml

Inherited Aml

Pure Familial Aml

Pure Familial Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia

Therapy-Related Aml And Myelodysplastic Syndrome

Acute Myeloid Leukemia, Secondary

Acute Non-Lymphoblastic Leukemia

Acute Non-Lymphocytic Leukemia

Acute Biphenotypic Leukemia

Acute Undifferentiated Leukemia

Acute Myeloblastic Leukaemia With Multilineage Dysplasia

Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission

Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Anaplastic Oligodendroglioma
Angiolipoma
High Grade Glioma

Malignant Glioma

Glial Cell Tumor

Glioma, Malignant

Malignant Neuroglial Tumor

Neuroglial Tumor

Glioma

Malignant Gliomas

Mediastinum Liposarcoma

Liposarcoma Of Mediastinum

Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas

Ewing Sarcoma

Neuroepithelioma

Ewing'S Tumor

Ewings Sarcoma

Ewing'S Sarcoma

Peripheral Neuroepithelioma

Primitive Neuroectodermal Tumor

ES

Ewings Sarcoma-Primitive Neuroectodermal Tumor

Localized Peripheral Primitive Neuroectodermal Tumor

Peripheral Primitive Neuroectodermal Tumor

Ewing Tumor

Sarcoma, Ewing'S

Extraosseous Ewing Tumor

Askin Tumor

Ewing'S Family Localized Tumor

Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Localized Ewing Sarcoma

Localized Ewing'S Sarcoma

Localized Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Localized Ewing'S Tumor

Pnet Of Thoracopulmonary Region

Ewing Family Of Tumors

Tumor Of The Ewing Family

Skeletal Ewing Sarcoma

Osseous Ewing Sarcoma

Ppnet

Peripheral Pnet

Extraskeletal Ewing Sarcoma

Eoe

Extraosseous Ewing Sarcoma

Extraskeletal Ewing Tumor

Esft

Ewing Sarcoma Family Of Tumors

Pne

Pnet

Pnet Of The Chest Wall

Sarcoma, Ewing

Neuroectodermal Tumors, Primitive, Peripheral

Neuroectodermal Tumor, Primitive

Disorder Of Eye

Askin'S Tumor

Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor

Neuroepithelioma, Peripheral

Lymphoma, Hodgkin, Classic

Hodgkin Lymphoma

Hodgkin Disease

Hodgkin'S Lymphoma

Hodgkins Lymphoma

Classic Hodgkin Lymphoma

CHL

Hodgkin Lymphoma, Susceptibility To

Hl

Hodgkin'S Sarcoma

Stage I Subdiaphragmatic Hodgkin Lymphoma

Stage Ii Subdiaphragmatic Hodgkin Lymphoma

Lymphoma, Hodgkin'S

Classic Hodgkin Disease

Hodgkin'S Disease

Lymphoma, Hodgkin, Susceptibility To

Hodgkin'S Disease Of Intrapelvic Lymph Nodes

Hodgkin'S Disease Of Lymph Nodes Of Inguinal Region And/Or Lower Limb

Malignant Lymphogranuloma

Malignant Lymphogranulomatosis

Malignant Hodgkin Lymphoma

Classical Hodgkin Lymphoma, Type Not Specified

Uterine Sarcoma

Sarcoma Of The Uterus

Uterine Corpus Sarcoma

Hemangiopericytoma, Malignant

Hemangiopericytoma

Haemangiopericytic Meningioma

Malignant Hemangiopericytoma

Solitary Fibrous Tumor

Myelodysplastic Syndrome

Myelodysplastic Syndromes

Myelodysplasia

MDS

Myelodysplastic Syndrome Included

Myelodysplastic Syndrome, Susceptibility To, Included

Myelodysplastic Syndrome, Somatic

Myelodysplastic Syndrome, Susceptibility To

Hepatoblastoma
Nasopharyngeal Carcinoma

Malignant Neoplasm Of Nasopharynx

Npc

Nasopharyngeal Cancer

Nasopharyngeal Carcinoma 1

Nasopharynx Carcinoma

Nasopharyngeal Neoplasms

Npca

Carcinoma Of Nasopharynx

Malignant Nasopharyngeal Tumor

Nasopharynx Cancer

Squamous Cell Carcinoma Of The Nasopharynx

Nasopharyngeal Neoplasm

Cancer Of Nasopharynx

Anaplastic Astrocytoma

Grade Iii Astrocytoma

Grade Iii Astrocytic Tumor

Astrocytoma, Anaplastic

Breast Adenocarcinoma

Mammary Adenocarcinoma

Adenocarcinoma Of Breast

Retroperitoneal Fibrosis

Idiopathic Retroperitoneal Fibrosis

Ormond Disease

Igg4-Related Retroperitoneal Fibrosis

Ormond'S Disease

Rpf - [Retroperitoneal Fibrosis]

Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon

Desmoid Tumor

Aggressive Fibromatosis

Desmoid Type Fibromatosis

Familial Infiltrative Fibromatosis

Desmoid Disorder, Hereditary

Fif

Fibromatosis, Familial Infiltrative

Deep Fibromatosis

Desmoid Fibromatosis

Hereditary Desmoid Disease

Musculoaponeurotic Fibromatosis

Desmoid-Type Fibromatosis

Fibromatosis, Aggressive

Desmoid Disease, Hereditary

Musculo-Aponeurotic Fibromatosis

Rhabdomyosarcoma 2

Alveolar Rhabdomyosarcoma

Rhabdomyosarcoma, Alveolar

Rhabdomyosarcoma Alveolar

RMS2

Rmsa

Rhabdomyosarcoma 2, Alveolar

Alveolar Childhood Rhabdomyosarcoma

Arms

Rhabdomyosarcoma, Type 2

Ocular Cancer

Eye Carcinoma

Eye Neoplasm

Eye Cancer

Eye Neoplasms

Malignant Eye Neoplasm

Neoplasm Of Eye

Neoplasm Of Eye Proper

Ocular Tumor

Carcinoma Of Eye

Ocular Carcinoma

Malignant Tumor Of Eye

Angiosarcoma

Hemangiosarcoma

Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour

Pleomorphic Rhabdomyosarcoma

Adult Pleomorphic Rhabdomyosarcoma

Anaplastic Rhabdomyosarcoma

Pleomorphic Rhabdomyosarcoma, Adult Type

Malignant Mesenchymoma

Malignant Mesenchymal Tumor

Mesenchymoma, Malignant

Sarcoma

Rat Malignant Renal Mesenchymal Tumor

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Felis catus MDM2 VGNC VGNC:68223
Mus musculus MDM2 MGD MGI:96952
Macaca mulatta MDM2 VGNC VGNC:74692
Rattus norvegicus MDM2 RGD RGD:1305332
Canis familiaris MDM2 VGNC VGNC:43106
Bos taurus MDM2 VGNC VGNC:31336
Others MDM2 NCBI