PSMB1 - proteasome 20S subunit beta 1 Gene

Homo sapiens

Also known as HC5; PSC5; PMSB1; NEDMHAL

Gene ID: 5689 | Gene type: protein coding

About PSMB1

Cytogenetic location: 6q27 Genomic coordinates (GRCh38): 6:170,535,120-170,553,307 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 216 orthologues and 18 paralogues. Ubiquitous expression in placenta (RPKM 83.1), fat (RPKM 75.6) and 25 other tissues.

Summary

The Proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave Peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified Proteasome, the immunoproteasome, is the processing of class I MHC Peptides. This gene encodes a member of the Proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq, Jul 2008]

PSMB1 Products(1)

mRNA	Protein	Name
NM_002793.4	NP_002784.1	proteasome subunit beta type-1

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	14733938	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
is active in cytoplasm	IDA IDA: Inferred from direct assay	34711951	GOA
is active in nucleus	IDA IDA: Inferred from direct assay	34711951	GOA
part of proteasome complex	IDA IDA: Inferred from direct assay	17323924	GOA
part of proteasome core complex	IDA IDA: Inferred from direct assay	34711951	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PSMB1 Protein Structure

Proteasome

0
100
200
241 a.a.

Protein Preferred Names

Protein Names

proteasome subunit beta type-1

macropain subunit C5

PSMB1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	PSMB1	P20618	KRT13	Homo sapiens	A1A4E9	Y2H Prey Pooling	25416956
Intra	PSMB1	P20618	KRT13	Homo sapiens	A1A4E9	Validated Y2H	25416956
Intra	PSMB1	P20618	KRT13	Homo sapiens	A1A4E9	Y2H Array	25416956
Intra	PSMB1	P20618	KRT40	Homo sapiens	Q6A162	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KRT40	Homo sapiens	Q6A162	Validated Y2H	32296183
Intra	PSMB1	P20618	KRT40	Homo sapiens	Q6A162	Y2H Array	32296183
Intra	PSMB1	P20618	BEND7	Homo sapiens	Q8N7W2-2	Y2H Array	32296183
Intra	PSMB1	P20618	BEND7	Homo sapiens	Q8N7W2-2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	BEND7	Homo sapiens	Q8N7W2-2	Validated Y2H	32296183
Intra	PSMB1	P20618	ZBTB32	Homo sapiens	A0A0C4DGF1	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	ZBTB32	Homo sapiens	A0A0C4DGF1	Y2H Array	32296183
Intra	PSMB1	P20618	KRTAP19-7	Homo sapiens	Q3SYF9	Y2H Array	32296183
Intra	PSMB1	P20618	KRTAP19-7	Homo sapiens	Q3SYF9	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KRTAP19-7	Homo sapiens	Q3SYF9	Validated Y2H	32296183
Intra	PSMB1	P20618	ZNF774	Homo sapiens	Q6NX45	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	ZNF774	Homo sapiens	Q6NX45	Validated Y2H	32296183
Intra	PSMB1	P20618	ZNF774	Homo sapiens	Q6NX45	Y2H Array	32296183
Intra	PSMB1	P20618	KRT34	Homo sapiens	O76011	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KRT34	Homo sapiens	O76011	Y2H Array	32296183
Intra	PSMB1	P20618	CLPP	Homo sapiens	Q16740	Validated Y2H	32296183
Intra	PSMB1	P20618	CLPP	Homo sapiens	Q16740	Y2H Array	32296183
Intra	PSMB1	P20618	CLPP	Homo sapiens	Q16740	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	CYTH4	Homo sapiens	Q9UIA0	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	CYTH4	Homo sapiens	Q9UIA0	Validated Y2H	32296183
Intra	PSMB1	P20618	CYTH4	Homo sapiens	Q9UIA0	Y2H Array	32296183
Intra	PSMB1	P20618	MTUS2	Homo sapiens	Q5JR59-3	Validated Y2H	32296183
Intra	PSMB1	P20618	MTUS2	Homo sapiens	Q5JR59-3	Y2H Array	32296183
Intra	PSMB1	P20618	MTUS2	Homo sapiens	Q5JR59-3	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	TRIM39	Homo sapiens	Q9HCM9-2	Y2H Array	32296183
Intra	PSMB1	P20618	TRIM39	Homo sapiens	Q9HCM9-2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	TRIM39	Homo sapiens	Q9HCM9-2	Validated Y2H	32296183
Intra	PSMB1	P20618	PIP4K2B	Homo sapiens	P78356-2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	PIP4K2B	Homo sapiens	P78356-2	Validated Y2H	32296183
Intra	PSMB1	P20618	PIP4K2B	Homo sapiens	P78356-2	Y2H Array	32296183
Intra	PSMB1	P20618	TLE5	Homo sapiens	Q08117-2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	TLE5	Homo sapiens	Q08117-2	Validated Y2H	32296183
Intra	PSMB1	P20618	TLE5	Homo sapiens	Q08117-2	Y2H Array	32296183
Intra	PSMB1	P20618	CTAG1A	Homo sapiens	P78358	Validated Y2H	32296183
Intra	PSMB1	P20618	CTAG1A	Homo sapiens	P78358	Y2H Array	32296183
Intra	PSMB1	P20618	CTAG1A	Homo sapiens	P78358	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	LCE1F	Homo sapiens	Q5T754	Validated Y2H	32296183
Intra	PSMB1	P20618	LCE1F	Homo sapiens	Q5T754	Y2H Array	32296183
Intra	PSMB1	P20618	LCE1F	Homo sapiens	Q5T754	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KRT36	Homo sapiens	O76013-2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KRT36	Homo sapiens	O76013-2	Y2H Array	32296183
Intra	PSMB1	P20618	ZNF438	Homo sapiens	Q7Z4V0	Validated Y2H	32296183
Intra	PSMB1	P20618	ZNF438	Homo sapiens	Q7Z4V0	Y2H Array	32296183
Intra	PSMB1	P20618	ZNF438	Homo sapiens	Q7Z4V0	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KRTAP15-1	Homo sapiens	Q3LI76	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KRTAP15-1	Homo sapiens	Q3LI76	Validated Y2H	32296183
Intra	PSMB1	P20618	KRTAP15-1	Homo sapiens	Q3LI76	Y2H Array	32296183
Intra	PSMB1	P20618	CAMK2G	Homo sapiens	Q13555-5	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	CAMK2G	Homo sapiens	Q13555-5	Validated Y2H	32296183
Intra	PSMB1	P20618	CAMK2G	Homo sapiens	Q13555-5	Y2H Array	32296183
Intra	PSMB1	P20618	LHX3	Homo sapiens	Q9UBR4-2	Validated Y2H	32296183
Intra	PSMB1	P20618	LHX3	Homo sapiens	Q9UBR4-2	Y2H Array	32296183
Intra	PSMB1	P20618	LHX3	Homo sapiens	Q9UBR4-2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	RIPPLY3	Homo sapiens	P57055	Y2H Array	32296183
Intra	PSMB1	P20618	RIPPLY3	Homo sapiens	P57055	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	RIPPLY3	Homo sapiens	P57055	Validated Y2H	32296183
Intra	PSMB1	P20618	LCE1C	Homo sapiens	Q5T751	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	LCE1C	Homo sapiens	Q5T751	Validated Y2H	32296183
Intra	PSMB1	P20618	LCE1C	Homo sapiens	Q5T751	Y2H Array	32296183
Intra	PSMB1	P20618	VAX1	Homo sapiens	Q5SQQ9-2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	VAX1	Homo sapiens	Q5SQQ9-2	Validated Y2H	32296183
Intra	PSMB1	P20618	VAX1	Homo sapiens	Q5SQQ9-2	Y2H Array	32296183
Intra	PSMB1	P20618	ZNF177	Homo sapiens	Q13360-2	Validated Y2H	32296183
Intra	PSMB1	P20618	ZNF177	Homo sapiens	Q13360-2	Y2H Array	32296183
Intra	PSMB1	P20618	ZNF177	Homo sapiens	Q13360-2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	TFPT	Homo sapiens	P0C1Z6	Y2H Array	32296183
Intra	PSMB1	P20618	TFPT	Homo sapiens	P0C1Z6	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KRTAP19-1	Homo sapiens	Q8IUB9	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KRTAP19-1	Homo sapiens	Q8IUB9	Validated Y2H	32296183
Intra	PSMB1	P20618	KRTAP19-1	Homo sapiens	Q8IUB9	Y2H Array	32296183
Intra	PSMB1	P20618	SCARA5	Homo sapiens	Q6ZMJ2-2	Validated Y2H	32296183
Intra	PSMB1	P20618	SCARA5	Homo sapiens	Q6ZMJ2-2	Y2H Array	32296183
Intra	PSMB1	P20618	SCARA5	Homo sapiens	Q6ZMJ2-2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	UBASH3B	Homo sapiens	Q8TF42	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	UBASH3B	Homo sapiens	Q8TF42	Validated Y2H	32296183
Intra	PSMB1	P20618	UBASH3B	Homo sapiens	Q8TF42	Y2H Array	32296183
Intra	PSMB1	P20618	KIFC3	Homo sapiens	Q9BVG8-5	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KIFC3	Homo sapiens	Q9BVG8-5	Y2H Array	32296183
Intra	PSMB1	P20618	KIFC3	Homo sapiens	Q9BVG8-5	Validated Y2H	32296183
Intra	PSMB1	P20618	RWDD2A	Homo sapiens	Q9UIY3	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	RWDD2A	Homo sapiens	Q9UIY3	Validated Y2H	32296183
Intra	PSMB1	P20618	RWDD2A	Homo sapiens	Q9UIY3	Y2H Array	32296183
Intra	PSMB1	P20618	NANOS3	Homo sapiens	P60323-2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	NANOS3	Homo sapiens	P60323-2	Validated Y2H	32296183
Intra	PSMB1	P20618	NANOS3	Homo sapiens	P60323-2	Y2H Array	32296183
Intra	PSMB1	P20618	KRTAP7-1	Homo sapiens	Q8IUC3	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KRTAP7-1	Homo sapiens	Q8IUC3	Validated Y2H	32296183
Intra	PSMB1	P20618	KRTAP7-1	Homo sapiens	Q8IUC3	Y2H Array	32296183
Intra	PSMB1	P20618	MLKL	Homo sapiens	Q8NB16-2	Y2H Array	32296183
Intra	PSMB1	P20618	MLKL	Homo sapiens	Q8NB16-2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	MLKL	Homo sapiens	Q8NB16-2	Validated Y2H	32296183
Intra	PSMB1	P20618	KIFC3	Homo sapiens	Q9BVG8	Y2H Array	25416956
Intra	PSMB1	P20618	KIFC3	Homo sapiens	Q9BVG8	Y2H Prey Pooling	25416956
Intra	PSMB1	P20618	KIFC3	Homo sapiens	Q9BVG8	Validated Y2H	25416956
Intra	PSMB1	P20618	MKRN3	Homo sapiens	Q13064	Validated Y2H	32296183
Intra	PSMB1	P20618	MKRN3	Homo sapiens	Q13064	Y2H Array	32296183
Intra	PSMB1	P20618	MKRN3	Homo sapiens	Q13064	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	GPBP1	Homo sapiens	Q86WP2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	GPBP1	Homo sapiens	Q86WP2	Validated Y2H	32296183
Intra	PSMB1	P20618	GPBP1	Homo sapiens	Q86WP2	Y2H Array	32296183
Intra	PSMB1	P20618	TTC33	Homo sapiens	Q6PID6	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	TTC33	Homo sapiens	Q6PID6	Validated Y2H	32296183
Intra	PSMB1	P20618	TTC33	Homo sapiens	Q6PID6	Y2H Array	32296183
Intra	PSMB1	P20618	JAKMIP1	Homo sapiens	Q96N16	Validated Y2H	32296183
Intra	PSMB1	P20618	JAKMIP1	Homo sapiens	Q96N16	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	JAKMIP1	Homo sapiens	Q96N16	Y2H Array	32296183
Intra	PSMB1	P20618	LZTFL1	Homo sapiens	Q9NQ48	Validated Y2H	32296183
Intra	PSMB1	P20618	LZTFL1	Homo sapiens	Q9NQ48	Y2H Array	32296183
Intra	PSMB1	P20618	LZTFL1	Homo sapiens	Q9NQ48	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	IMPACT	Homo sapiens	Q9P2X3	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	IMPACT	Homo sapiens	Q9P2X3	Validated Y2H	32296183
Intra	PSMB1	P20618	IMPACT	Homo sapiens	Q9P2X3	Y2H Array	32296183
Intra	PSMB1	P20618	MRNIP	Homo sapiens	Q6NTE8	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	MRNIP	Homo sapiens	Q6NTE8	Y2H Array	32296183
Intra	PSMB1	P20618	MRNIP	Homo sapiens	Q6NTE8	Validated Y2H	32296183
Intra	PSMB1	P20618	LDB2	Homo sapiens	O43679	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	LDB2	Homo sapiens	O43679	Y2H Array	32296183
Intra	PSMB1	P20618	XPA	Homo sapiens	P23025	Validated Y2H	32296183
Intra	PSMB1	P20618	XPA	Homo sapiens	P23025	Y2H Array	32296183
Intra	PSMB1	P20618	XPA	Homo sapiens	P23025	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	PYCR3	Homo sapiens	Q53H96	Y2H Array	32296183
Intra	PSMB1	P20618	PYCR3	Homo sapiens	Q53H96	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	PYCR3	Homo sapiens	Q53H96	Validated Y2H	32296183
Intra	PSMB1	P20618	SMAD3	Homo sapiens	P84022	Validated Y2H	32296183
Intra	PSMB1	P20618	SMAD3	Homo sapiens	P84022	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	SMAD3	Homo sapiens	P84022	Y2H Array	32296183
Intra	PSMB1	P20618	CCM2L	Homo sapiens	Q9NUG4	Validated Y2H	32296183
Intra	PSMB1	P20618	CCM2L	Homo sapiens	Q9NUG4	Y2H Array	32296183
Intra	PSMB1	P20618	CCM2L	Homo sapiens	Q9NUG4	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	TRAF2	Homo sapiens	Q12933	Validated Y2H	32296183
Intra	PSMB1	P20618	TRAF2	Homo sapiens	Q12933	Y2H Array	32296183
Intra	PSMB1	P20618	TRAF2	Homo sapiens	Q12933	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	GEMIN4	Homo sapiens	P57678	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	GEMIN4	Homo sapiens	P57678	Validated Y2H	32296183
Intra	PSMB1	P20618	GEMIN4	Homo sapiens	P57678	Y2H Array	32296183
Intra	PSMB1	P20618	PSMB5	Homo sapiens	P28074	Anti Tag CoIP	33961781
Intra	PSMB1	P20618	PSMB5	Homo sapiens	P28074	Y2H	17948026
Intra	PSMB1	P20618	PSMB5	Homo sapiens	P28074	Y2H	14733938
Intra	PSMB1	P20618	PSMB5	Homo sapiens	P28074	Anti Tag CoIP	28514442
Intra	PSMB1	P20618	SMARCB1	Homo sapiens	Q12824-2	Validated Y2H	32296183
Intra	PSMB1	P20618	SMARCB1	Homo sapiens	Q12824-2	Y2H Array	32296183
Intra	PSMB1	P20618	SMARCB1	Homo sapiens	Q12824-2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	TRAF1	Homo sapiens	Q13077	Validated Y2H	32296183
Intra	PSMB1	P20618	TRAF1	Homo sapiens	Q13077	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	TRAF1	Homo sapiens	Q13077	Y2H Array	25416956
Intra	PSMB1	P20618	TRAF1	Homo sapiens	Q13077	Y2H Array	32296183
Intra	PSMB1	P20618	PSMD4	Homo sapiens	P55036	Anti Tag CoIP	35271311
Intra	PSMB1	P20618	PSMB2	Homo sapiens	P49721	Anti Tag CoIP	35271311
Intra	PSMB1	P20618	PSMB2	Homo sapiens	P49721	Y2H	17948026
Intra	PSMB1	P20618	PSMA1	Homo sapiens	P25786	Validated Y2H	32296183
Intra	PSMB1	P20618	PSMA1	Homo sapiens	P25786	Y2H Array	32296183
Intra	PSMB1	P20618	PSMA1	Homo sapiens	P25786	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	PSMA1	Homo sapiens	P25786	Anti Tag CoIP	33961781
Intra	PSMB1	P20618	GADD45GIP1	Homo sapiens	Q8TAE8	Y2H Array	32296183
Intra	PSMB1	P20618	GADD45GIP1	Homo sapiens	Q8TAE8	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	GADD45GIP1	Homo sapiens	Q8TAE8	Validated Y2H	32296183
Intra	PSMB1	P20618	FAM136A	Homo sapiens	Q96C01	Validated Y2H	32296183
Intra	PSMB1	P20618	FAM136A	Homo sapiens	Q96C01	Y2H Array	32296183
Intra	PSMB1	P20618	FAM136A	Homo sapiens	Q96C01	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	RNF8	Homo sapiens	O76064	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	RNF8	Homo sapiens	O76064	Y2H Array	32296183
Intra	PSMB1	P20618	COG6	Homo sapiens	Q9Y2V7	Y2H Array	32296183
Intra	PSMB1	P20618	COG6	Homo sapiens	Q9Y2V7	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	COG6	Homo sapiens	Q9Y2V7	Validated Y2H	32296183
Intra	PSMB1	P20618	THAP6	Homo sapiens	Q8TBB0	Y2H Array	32296183
Intra	PSMB1	P20618	THAP6	Homo sapiens	Q8TBB0	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	THAP6	Homo sapiens	Q8TBB0	Validated Y2H	32296183
Intra	PSMB1	P20618	ZNF688	Homo sapiens	P0C7X2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	ZNF688	Homo sapiens	P0C7X2	Y2H Array	32296183
Intra	PSMB1	P20618	GEMIN2	Homo sapiens	O14893	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	GEMIN2	Homo sapiens	O14893	Y2H Array	32296183
Intra	PSMB1	P20618	HTT	Homo sapiens	P42858	Y2H Array	32814053
Intra	PSMB1	P20618	HTT	Homo sapiens	P42858	Y2H Pooling	32814053
Intra	PSMB1	P20618	HTT	Homo sapiens	P42858	Validated Y2H	32814053
Intra	PSMB1	P20618	BIRC7	Homo sapiens	Q96CA5	Validated Y2H	32296183
Intra	PSMB1	P20618	BIRC7	Homo sapiens	Q96CA5	Y2H Array	32296183
Intra	PSMB1	P20618	BIRC7	Homo sapiens	Q96CA5	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	OTUD7B	Homo sapiens	Q6GQQ9	Y2H Array	32296183
Intra	PSMB1	P20618	OTUD7B	Homo sapiens	Q6GQQ9	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	OTUD7B	Homo sapiens	Q6GQQ9	Validated Y2H	32296183
Intra	PSMB1	P20618	OIP5	Homo sapiens	O43482	Y2H Array	32296183
Intra	PSMB1	P20618	OIP5	Homo sapiens	O43482	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	PSMB7	Homo sapiens	Q99436	Anti Tag CoIP	35271311
Intra	PSMB1	P20618	PSMB7	Homo sapiens	Q99436	Y2H	14733938
Intra	PSMB1	P20618	PSMB7	Homo sapiens	Q99436	Anti Tag CoIP	33961781
Intra	PSMB1	P20618	PSMB7	Homo sapiens	Q99436	Anti Tag CoIP	28514442
Intra	PSMB1	P20618	PSMB3	Homo sapiens	P49720	Y2H	17948026
Intra	PSMB1	P20618	PSMB3	Homo sapiens	P49720	Y2H	14733938
Intra	PSMB1	P20618	PSMB4	Homo sapiens	P28070	Y2H Array	32296183
Intra	PSMB1	P20618	PSMB4	Homo sapiens	P28070	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	PSMB4	Homo sapiens	P28070	Anti Tag CoIP	33961781
Intra	PSMB1	P20618	PSMB4	Homo sapiens	P28070	Anti Tag CoIP	28514442
Intra	PSMB1	P20618	PSMB4	Homo sapiens	P28070	Validated Y2H	32296183
Intra	PSMB1	P20618	GTPBP2	Homo sapiens	Q9BX10	Y2H Array	32296183
Intra	PSMB1	P20618	GTPBP2	Homo sapiens	Q9BX10	Validated Y2H	32296183
Intra	PSMB1	P20618	GTPBP2	Homo sapiens	Q9BX10	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	POMP	Homo sapiens	Q9Y244	Anti Tag CoIP	28514442
Intra	PSMB1	P20618	POMP	Homo sapiens	Q9Y244	Anti Tag CoIP	33961781
Intra	PSMB1	P20618	POMP	Homo sapiens	Q9Y244	Anti Tag CoIP	35271311
Intra	PSMB1	P20618	SH3GL1	Homo sapiens	Q99961	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	SH3GL1	Homo sapiens	Q99961	Validated Y2H	32296183
Intra	PSMB1	P20618	SH3GL1	Homo sapiens	Q99961	Y2H Array	32296183
Intra	PSMB1	P20618	AGR2	Homo sapiens	O95994	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	AGR2	Homo sapiens	O95994	Y2H Array	32296183
Intra	PSMB1	P20618	STMN2	Homo sapiens	Q93045	Validated Y2H	32296183
Intra	PSMB1	P20618	STMN2	Homo sapiens	Q93045	Y2H Array	32296183
Intra	PSMB1	P20618	STMN2	Homo sapiens	Q93045	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KATNBL1	Homo sapiens	Q9H079	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KATNBL1	Homo sapiens	Q9H079	Validated Y2H	32296183
Intra	PSMB1	P20618	KATNBL1	Homo sapiens	Q9H079	Y2H Array	32296183
Intra	PSMB1	P20618	GRIPAP1	Homo sapiens	Q4V328	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	GRIPAP1	Homo sapiens	Q4V328	Validated Y2H	32296183
Intra	PSMB1	P20618	GRIPAP1	Homo sapiens	Q4V328	Y2H Array	32296183
Intra	PSMB1	P20618	TRIM27	Homo sapiens	P14373	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	TRIM27	Homo sapiens	P14373	Y2H Array	25416956
Intra	PSMB1	P20618	TRIM27	Homo sapiens	P14373	Y2H Array	32296183
Intra	PSMB1	P20618	AHSP	Homo sapiens	Q9NZD4	Y2H Array	32296183
Intra	PSMB1	P20618	AHSP	Homo sapiens	Q9NZD4	Validated Y2H	32296183
Intra	PSMB1	P20618	AHSP	Homo sapiens	Q9NZD4	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	WFS1	Homo sapiens	O76024	Y2H Pooling	32814053
Intra	PSMB1	P20618	WFS1	Homo sapiens	O76024	Validated Y2H	32814053
Intra	PSMB1	P20618	WFS1	Homo sapiens	O76024	Y2H Array	32814053
Intra	PSMB1	P20618	LENG1	Homo sapiens	Q96BZ8	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	LENG1	Homo sapiens	Q96BZ8	Validated Y2H	32296183
Intra	PSMB1	P20618	LENG1	Homo sapiens	Q96BZ8	Y2H Array	32296183
Intra	PSMB1	P20618	MAPRE3	Homo sapiens	Q9UPY8	Validated Y2H	25416956
Intra	PSMB1	P20618	MAPRE3	Homo sapiens	Q9UPY8	Y2H Array	25416956
Intra	PSMB1	P20618	KRT15	Homo sapiens	P19012	Y2H Prey Pooling	25416956
Intra	PSMB1	P20618	KRT15	Homo sapiens	P19012	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KRT15	Homo sapiens	P19012	Y2H Array	25416956
Intra	PSMB1	P20618	KRT15	Homo sapiens	P19012	Y2H Array	32296183
Intra	PSMB1	P20618	TRIM23	Homo sapiens	P36406	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	TRIM23	Homo sapiens	P36406	Y2H Array	32296183
Intra	PSMB1	P20618	TRIM23	Homo sapiens	P36406	Validated Y2H	32296183
Intra	PSMB1	P20618	HMG20A	Homo sapiens	Q9NP66	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	HMG20A	Homo sapiens	Q9NP66	Validated Y2H	32296183
Intra	PSMB1	P20618	HMG20A	Homo sapiens	Q9NP66	Y2H Array	32296183
Intra	PSMB1	P20618	HOXA1	Homo sapiens	P49639	Validated Y2H	32296183
Intra	PSMB1	P20618	HOXA1	Homo sapiens	P49639	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	HOXA1	Homo sapiens	P49639	Y2H Array	32296183
Intra	PSMB1	P20618	FAM50B	Homo sapiens	Q9Y247	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	FAM50B	Homo sapiens	Q9Y247	Validated Y2H	32296183
Intra	PSMB1	P20618	FAM50B	Homo sapiens	Q9Y247	Y2H Array	32296183
Intra	PSMB1	P20618	NME4	Homo sapiens	O00746	Y2H Array	32296183
Intra	PSMB1	P20618	NME4	Homo sapiens	O00746	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	TOLLIP	Homo sapiens	Q9H0E2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	TOLLIP	Homo sapiens	Q9H0E2	Validated Y2H	32296183
Intra	PSMB1	P20618	TOLLIP	Homo sapiens	Q9H0E2	Y2H Array	32296183
Intra	PSMB1	P20618	RPRD1B	Homo sapiens	Q9NQG5	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	RPRD1B	Homo sapiens	Q9NQG5	Validated Y2H	32296183
Intra	PSMB1	P20618	RPRD1B	Homo sapiens	Q9NQG5	Y2H Array	32296183
Intra	PSMB1	P20618	DDI1	Homo sapiens	Q8WTU0	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	DDI1	Homo sapiens	Q8WTU0	Validated Y2H	32296183
Intra	PSMB1	P20618	DDI1	Homo sapiens	Q8WTU0	Y2H Array	32296183
Intra	PSMB1	P20618	NDUFV1	Homo sapiens	P49821	Y2H Array	32814053
Intra	PSMB1	P20618	NDUFV1	Homo sapiens	P49821	Y2H Pooling	32814053
Intra	PSMB1	P20618	NDUFV1	Homo sapiens	P49821	Validated Y2H	32814053
Intra	PSMB1	P20618	RYBP	Homo sapiens	Q8N488	Y2H Array	32296183
Intra	PSMB1	P20618	RYBP	Homo sapiens	Q8N488	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	RYBP	Homo sapiens	Q8N488	Validated Y2H	32296183
Intra	PSMB1	P20618	ARNT2	Homo sapiens	Q9HBZ2	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	ARNT2	Homo sapiens	Q9HBZ2	Y2H Array	32296183
Intra	PSMB1	P20618	LIN7B	Homo sapiens	Q9HAP6	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	LIN7B	Homo sapiens	Q9HAP6	Validated Y2H	32296183
Intra	PSMB1	P20618	LIN7B	Homo sapiens	Q9HAP6	Y2H Array	32296183
Intra	PSMB1	P20618	LMO1	Homo sapiens	P25800	Validated Y2H	32296183
Intra	PSMB1	P20618	LMO1	Homo sapiens	P25800	Y2H Array	32296183
Intra	PSMB1	P20618	LMO1	Homo sapiens	P25800	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KHDC4	Homo sapiens	Q7Z7F0-4	Validated Y2H	32296183
Intra	PSMB1	P20618	KHDC4	Homo sapiens	Q7Z7F0-4	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	KHDC4	Homo sapiens	Q7Z7F0-4	Y2H Array	32296183
Intra	PSMB1	P20618	KRT31	Homo sapiens	Q15323	Validated Y2H	32296183
Intra	PSMB1	P20618	KRT31	Homo sapiens	Q15323	Y2H Array	32296183
Intra	PSMB1	P20618	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	PLEKHG4	Homo sapiens	Q58EX7	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	PLEKHG4	Homo sapiens	Q58EX7	Validated Y2H	32296183
Intra	PSMB1	P20618	BPIFA1	Homo sapiens	Q9NP55	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	BPIFA1	Homo sapiens	Q9NP55	Validated Y2H	32296183
Intra	PSMB1	P20618	BPIFA1	Homo sapiens	Q9NP55	Y2H Array	32296183
Intra	PSMB1	P20618	CDC14B	Homo sapiens	O60729	Y2H Prey Pooling	32296183
Intra	PSMB1	P20618	CDC14B	Homo sapiens	O60729	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

PSMB1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P83718	PSMB1 Antibody	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat

Related Diseases

Diseases

Alias

Neurodevelopmental Disorder With Microcephaly, Hypotonia, And Absent Language

NEDMHAL

Hypocalciuric Hypercalcemia, Familial, Type I

HHC1	Familial Hypocalciuric Hypercalcemia 1
Fhh1	Familial Benign Hypercalcemia 1
Fbh1	Hypocalciuric Hypercalcemia, Type I
Fhh Type 1	Hhc
Fhh	Hypercalcemia, Familial Benign
Hypocalciuric Hypercalcemia Type I	Familial Hypocalciuric Hypercalcemia Type 1
Hypocalciuric Hypercalcemia, Familial, Type 1	Familial Hypocalciuric Hypercalcemia Type I
Familial Benign Hypercalcemia Type 1	Hypercalcemia, Familial Benign Type 1
Hypocalciuric Hypercalcemia, Familial 1	Familial Benign Hypocalciuric Hypercalcemia 1
Fbhh1

Cystic Fibrosis

Mucoviscidosis	CF
Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis	Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis
Cystic Fibrosis Lung Disease, Modifier Of	Cystic Fibrosis Of Pancreas
Fibrocystic Disease Of Pancreas	Cf - [Cystic Fibrosis]
Cystic Fibrosis Nos	Fibrocystic Disease
Fibrocystic Disease Of The Pancreas	Mucoviscidosis Of Pancreas
Nonproliferative Fibrocystic Disease	Pancreatic Cystic Fibrosis

Microcephaly

Microencephaly	Microcephalus
Microcephalic	Nanocephaly
Congenital Microcephaly	Brain Hypoplasia
Brain Nondevelopment	Cephalic Hypoplasia
Undeveloped Cerebrum	Undeveloped Brain
Micrencephalon	Micrencephaly

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11299	PSMB1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	PSMB1	VGNC	VGNC:69107
Rattus norvegicus	PSMB1	RGD	RGD:621092
Bos taurus	PSMB1	VGNC	VGNC:33444
Mus musculus	PSMB1	MGD	MGI:104884
Canis familiaris	PSMB1	VGNC	VGNC:54344
Macaca mulatta	PSMB1	VGNC	VGNC:76442

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