2. Gene
  3. MKRN3 - makorin ring finger protein 3 Gene

MKRN3 - makorin ring finger protein 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CPPB2; D15S9; RNF63; ZFP127; ZNF127

Gene ID: 7681 | Gene type: protein coding

About MKRN3

Cytogenetic location: 15q11.2 Genomic coordinates (GRCh38): 15:23,565,674-23,568,044 (from NCBI)

This gene has 12 transcripts (splice variants), 73 orthologues, 2 paralogues and is associated with 3 phenotypes.

Summary

The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. [provided by RefSeq, Jul 2008]

MKRN3 Products(1)

mRNA Protein Name
NM_005664.4 NP_005655.1 probable E3 ubiquitin-protein ligase makorin-3
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
22493164 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
19549727 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MKRN3 Protein Structure

zf-C3HC4

zf-C3HC4: Zinc finger, C3HC4 type (RING finger) (311 - 364)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 507 a.a.
Protein Preferred Names Protein Names

probable E3 ubiquitin-protein ligase makorin-3

RING finger protein 63

MKRN3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra MKRN3 Q13064 ADAMTSL4 Homo sapiens Q6UY14-3
Validated Y2H
32296183
Intra MKRN3 Q13064 ADAMTSL4 Homo sapiens Q6UY14-3
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ADAMTSL4 Homo sapiens Q6UY14-3
Y2H Array
32296183
Intra MKRN3 Q13064 RTP5 Homo sapiens Q14D33
Validated Y2H
32296183
Intra MKRN3 Q13064 TSGA10IP Homo sapiens Q3SY00
Validated Y2H
32296183
Intra MKRN3 Q13064 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Array
32296183
Intra MKRN3 Q13064 KRTAP19-7 Homo sapiens Q3SYF9
Validated Y2H
32296183
Intra MKRN3 Q13064 KRTAP8-1 Homo sapiens Q8IUC2
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 KRTAP8-1 Homo sapiens Q8IUC2
Validated Y2H
32296183
Intra MKRN3 Q13064 KRTAP8-1 Homo sapiens Q8IUC2
Y2H Array
32296183
Intra MKRN3 Q13064 RIBC1 Homo sapiens Q8N443
Validated Y2H
32296183
Intra MKRN3 Q13064 ODAD4 Homo sapiens Q96NG3
Validated Y2H
25416956
Intra MKRN3 Q13064 ODAD4 Homo sapiens Q96NG3
Y2H Array
25416956
Intra MKRN3 Q13064 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra MKRN3 Q13064 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 LAGE3 Homo sapiens Q14657
Validated Y2H
32296183
Intra MKRN3 Q13064 UQCC2 Homo sapiens Q9BRT2
Y2H Array
32296183
Intra MKRN3 Q13064 UQCC2 Homo sapiens Q9BRT2
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 UQCC2 Homo sapiens Q9BRT2
Validated Y2H
32296183
Intra MKRN3 Q13064 POLR1C Homo sapiens O15160
Validated Y2H
27107012
Intra MKRN3 Q13064 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra MKRN3 Q13064 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra MKRN3 Q13064 GOLGA6A Homo sapiens Q9NYA3
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 GOLGA6A Homo sapiens Q9NYA3
Validated Y2H
32296183
Intra MKRN3 Q13064 GOLGA6A Homo sapiens Q9NYA3
Y2H Array
32296183
Intra MKRN3 Q13064 KRTAP6-2 Homo sapiens Q3LI66
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 KRTAP6-2 Homo sapiens Q3LI66
Validated Y2H
32296183
Intra MKRN3 Q13064 KRTAP6-2 Homo sapiens Q3LI66
Y2H Array
32296183
Intra MKRN3 Q13064 ZIM2 Homo sapiens Q9NZV7
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ZIM2 Homo sapiens Q9NZV7
Validated Y2H
32296183
Intra MKRN3 Q13064 ZIM2 Homo sapiens Q9NZV7
Y2H Array
32296183
Intra MKRN3 Q13064 RBPMS2 Homo sapiens Q6ZRY4
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 RBPMS2 Homo sapiens Q6ZRY4
Validated Y2H
32296183
Intra MKRN3 Q13064 RBPMS2 Homo sapiens Q6ZRY4
Y2H Array
32296183
Intra MKRN3 Q13064 MCCD1 Homo sapiens P59942
Y2H Array
32296183
Intra MKRN3 Q13064 MCCD1 Homo sapiens P59942
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ADRA2C Homo sapiens P18825
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ADRA2C Homo sapiens P18825
Y2H Array
32296183
Intra MKRN3 Q13064 WDR25 Homo sapiens Q64LD2-2
Validated Y2H
32296183
Intra MKRN3 Q13064 WWOX Homo sapiens Q9NZC7-5
Y2H Array
32296183
Intra MKRN3 Q13064 WWOX Homo sapiens Q9NZC7-5
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 WWOX Homo sapiens Q9NZC7-5
Validated Y2H
32296183
Intra MKRN3 Q13064 HSF4 Homo sapiens Q9ULV5-2
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 HSF4 Homo sapiens Q9ULV5-2
Validated Y2H
32296183
Intra MKRN3 Q13064 HSF4 Homo sapiens Q9ULV5-2
Y2H Array
32296183
Intra MKRN3 Q13064 KRTAP19-2 Homo sapiens Q3LHN2
Y2H Array
32296183
Intra MKRN3 Q13064 KRTAP19-2 Homo sapiens Q3LHN2
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 KRTAP19-2 Homo sapiens Q3LHN2
Validated Y2H
32296183
Intra MKRN3 Q13064 POMC Homo sapiens P01189
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 POMC Homo sapiens P01189
Y2H Array
32296183
Intra MKRN3 Q13064 CERCAM Homo sapiens Q5T4B2
Validated Y2H
32296183
Intra MKRN3 Q13064 CERCAM Homo sapiens Q5T4B2
Y2H Array
32296183
Intra MKRN3 Q13064 CERCAM Homo sapiens Q5T4B2
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ZBTB42 Homo sapiens B2RXF5
Y2H Array
32296183
Intra MKRN3 Q13064 ZBTB42 Homo sapiens B2RXF5
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 NDUFB7 Homo sapiens P17568
Y2H Array
32296183
Intra MKRN3 Q13064 NDUFB7 Homo sapiens P17568
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 KRTAP19-6 Homo sapiens Q3LI70
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 KRTAP19-6 Homo sapiens Q3LI70
Validated Y2H
32296183
Intra MKRN3 Q13064 KRTAP19-6 Homo sapiens Q3LI70
Y2H Array
32296183
Intra MKRN3 Q13064 RSPO4 Homo sapiens Q2I0M5
Validated Y2H
32296183
Intra MKRN3 Q13064 RSPO4 Homo sapiens Q2I0M5
Y2H Array
32296183
Intra MKRN3 Q13064 RSPO4 Homo sapiens Q2I0M5
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 SPMIP5 Homo sapiens Q8WW14-2
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 SPMIP5 Homo sapiens Q8WW14-2
Validated Y2H
32296183
Intra MKRN3 Q13064 SPMIP5 Homo sapiens Q8WW14-2
Y2H Array
32296183
Intra MKRN3 Q13064 IGF1 Homo sapiens P05019-2
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 IGF1 Homo sapiens P05019-2
Y2H Array
32296183
Intra MKRN3 Q13064 STH Homo sapiens Q8IWL8
Validated Y2H
32296183
Intra MKRN3 Q13064 STH Homo sapiens Q8IWL8
Y2H Array
32296183
Intra MKRN3 Q13064 STH Homo sapiens Q8IWL8
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ZFP57 Homo sapiens Q9NU63-3
Validated Y2H
32296183
Intra MKRN3 Q13064 ZFP57 Homo sapiens Q9NU63-3
Y2H Array
32296183
Intra MKRN3 Q13064 ZFP57 Homo sapiens Q9NU63-3
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 PTK6 Homo sapiens Q13882
Validated Y2H
32296183
Intra MKRN3 Q13064 PTK6 Homo sapiens Q13882
Y2H Array
32296183
Intra MKRN3 Q13064 PTK6 Homo sapiens Q13882
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 KIFC3 Homo sapiens Q9BVG8-5
Validated Y2H
32296183
Intra MKRN3 Q13064 MGC50722 Homo sapiens Q8IVT4
Validated Y2H
32296183
Intra MKRN3 Q13064 TPRX1 Homo sapiens Q8N7U7-2
Validated Y2H
32296183
Intra MKRN3 Q13064 PRPF31 Homo sapiens Q8WWY3
Validated Y2H
25416956
Intra MKRN3 Q13064 PRPF31 Homo sapiens Q8WWY3
Validated Y2H
32296183
Intra MKRN3 Q13064 PRPF31 Homo sapiens Q8WWY3
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 ANKRD11 Homo sapiens X5D778
Validated Y2H
32296183
Intra MKRN3 Q13064 HOXD12 Homo sapiens P35452-2
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 HOXD12 Homo sapiens P35452-2
Y2H Array
32296183
Intra MKRN3 Q13064 FAM110A Homo sapiens Q9BQ89
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 FAM110A Homo sapiens Q9BQ89
Validated Y2H
32296183
Intra MKRN3 Q13064 FAM110A Homo sapiens Q9BQ89
Y2H Array
25416956
Intra MKRN3 Q13064 ACOT11 Homo sapiens Q8WXI4-2
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ACOT11 Homo sapiens Q8WXI4-2
Y2H Array
32296183
Intra MKRN3 Q13064 ACOT11 Homo sapiens Q8WXI4-2
Validated Y2H
32296183
Intra MKRN3 Q13064 CDCA4 Homo sapiens Q9BXL8
Validated Y2H
32296183
Intra MKRN3 Q13064 CDCA4 Homo sapiens Q9BXL8
Y2H Array
32296183
Intra MKRN3 Q13064 CDCA4 Homo sapiens Q9BXL8
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 KRTAP7-1 Homo sapiens Q8IUC3
Y2H Array
32296183
Intra MKRN3 Q13064 KRTAP7-1 Homo sapiens Q8IUC3
Validated Y2H
32296183
Intra MKRN3 Q13064 KRTAP7-1 Homo sapiens Q8IUC3
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 KRTAP21-2 Homo sapiens Q3LI59
Validated Y2H
32296183
Intra MKRN3 Q13064 KRTAP21-2 Homo sapiens Q3LI59
Y2H Array
32296183
Intra MKRN3 Q13064 KRTAP21-2 Homo sapiens Q3LI59
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 APBB2 Homo sapiens Q92870-2
Validated Y2H
32814053
Intra MKRN3 Q13064 APBB2 Homo sapiens Q92870-2
Y2H Array
32814053
Intra MKRN3 Q13064 APBB2 Homo sapiens Q92870-2
Y2H Pooling
32814053
Intra MKRN3 Q13064 MDM4 Homo sapiens O15151
Y2H Array
22493164
Intra MKRN3 Q13064 TCHP Homo sapiens Q9BT92
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 MDM4 Homo sapiens O15151
BFG-2H
27107012
Intra MKRN3 Q13064 MDM4 Homo sapiens O15151
Y2H Array
32296183
Intra MKRN3 Q13064 TCHP Homo sapiens Q9BT92
Y2H Array
31515488
Intra MKRN3 Q13064 MDM4 Homo sapiens O15151
Anti Tag CoIP
22493164
Intra MKRN3 Q13064 MDM4 Homo sapiens O15151
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 TCHP Homo sapiens Q9BT92
Validated Y2H
32296183
Intra MKRN3 Q13064 FARS2 Homo sapiens O95363
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 FARS2 Homo sapiens O95363
Y2H Array
25416956
Cross MKRN3 Q13064 P0C6X7-PRO_0000037311 Human SARS coronavirus P0C6X7-PRO_0000037311
Lumier
22046132
Cross MKRN3 Q13064 P0C6X7-PRO_0000037311 Human SARS coronavirus P0C6X7-PRO_0000037311
Y2H Pooling
22046132
Intra MKRN3 Q13064 BLZF1 Homo sapiens Q9H2G9
Validated Y2H
32296183
Intra MKRN3 Q13064 BLZF1 Homo sapiens Q9H2G9
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 BLZF1 Homo sapiens Q9H2G9
Y2H Array
32296183
Intra MKRN3 Q13064 KANK2 Homo sapiens Q63ZY3
Validated Y2H
32296183
Intra MKRN3 Q13064 SYNGAP1 Homo sapiens Q96PV0
Y2H Array
32296183
Intra MKRN3 Q13064 SYNGAP1 Homo sapiens Q96PV0
Validated Y2H
32296183
Intra MKRN3 Q13064 SYNGAP1 Homo sapiens Q96PV0
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 PTH1R Homo sapiens Q03431
Y2H Array
32296183
Intra MKRN3 Q13064 PTH1R Homo sapiens Q03431
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 MEOX1 Homo sapiens P50221
Y2H Array
32296183
Intra MKRN3 Q13064 MEOX1 Homo sapiens P50221
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 NABP1 Homo sapiens Q96AH0
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 NABP1 Homo sapiens Q96AH0
Y2H Array
25416956
Intra MKRN3 Q13064 TFAP2A Homo sapiens P05549
Y2H Array
25416956
Intra MKRN3 Q13064 TFAP2A Homo sapiens P05549
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 SMYD3 Homo sapiens Q9H7B4
Validated Y2H
32296183
Intra MKRN3 Q13064 SMYD3 Homo sapiens Q9H7B4
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 SLPI Homo sapiens P03973
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 SLPI Homo sapiens P03973
Y2H Array
32296183
Intra MKRN3 Q13064 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra MKRN3 Q13064 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 SMARCD1 Homo sapiens Q96GM5
Validated Y2H
32296183
Intra MKRN3 Q13064 GADD45GIP1 Homo sapiens Q8TAE8
Validated Y2H
32296183
Intra MKRN3 Q13064 TARDBP Homo sapiens Q13148
Validated Y2H
32814053
Intra MKRN3 Q13064 TARDBP Homo sapiens Q13148
Y2H Array
32814053
Intra MKRN3 Q13064 TARDBP Homo sapiens Q13148
Y2H Pooling
32814053
Intra MKRN3 Q13064 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra MKRN3 Q13064 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ZNF688 Homo sapiens P0C7X2
Y2H Array
32296183
Intra MKRN3 Q13064 ZNF688 Homo sapiens P0C7X2
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 UBE2K Homo sapiens P61086
Y2H Array
32814053
Intra MKRN3 Q13064 UBE2K Homo sapiens P61086
Validated Y2H
32814053
Intra MKRN3 Q13064 UBE2K Homo sapiens P61086
Y2H Pooling
32814053
Intra MKRN3 Q13064 SFN Homo sapiens P31947
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 SFN Homo sapiens P31947
Y2H Array
25416956
Intra MKRN3 Q13064 PMP22 Homo sapiens A0A6Q8PF08
Validated Y2H
32814053
Intra MKRN3 Q13064 PMP22 Homo sapiens A0A6Q8PF08
Y2H Pooling
32814053
Intra MKRN3 Q13064 PMP22 Homo sapiens A0A6Q8PF08
Y2H Array
32814053
Intra MKRN3 Q13064 BCL2L11 Homo sapiens O43521
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 BCL2L11 Homo sapiens O43521
Y2H Array
32296183
Intra MKRN3 Q13064 EFEMP1 Homo sapiens Q12805
Y2H Array
32296183
Intra MKRN3 Q13064 EFEMP1 Homo sapiens Q12805
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ZNF835 Homo sapiens Q9Y2P0
Y2H Array
32296183
Intra MKRN3 Q13064 ZNF835 Homo sapiens Q9Y2P0
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ZNF835 Homo sapiens Q9Y2P0
Validated Y2H
32296183
Intra MKRN3 Q13064 PKN1 Homo sapiens Q16512
Validated Y2H
32296183
Intra MKRN3 Q13064 ARMC5 Homo sapiens Q96C12
Validated Y2H
32296183
Intra MKRN3 Q13064 ARMC5 Homo sapiens Q96C12
Y2H Array
32296183
Intra MKRN3 Q13064 ARMC5 Homo sapiens Q96C12
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 KLHL38 Homo sapiens Q2WGJ6
Validated Y2H
32296183
Intra MKRN3 Q13064 ZNF587 Homo sapiens Q96SQ5
Validated Y2H
32296183
Intra MKRN3 Q13064 TCEA2 Homo sapiens Q15560
Validated Y2H
25416956
Intra MKRN3 Q13064 TCEA2 Homo sapiens Q15560
Y2H Array
25416956
Intra MKRN3 Q13064 TCEA2 Homo sapiens Q15560
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Intra MKRN3 Q13064 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ECSIT Homo sapiens Q9BQ95
Validated Y2H
32296183
Intra MKRN3 Q13064 ECSIT Homo sapiens Q9BQ95
Y2H Array
32296183
Intra MKRN3 Q13064 ECSIT Homo sapiens Q9BQ95
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 HEXB Homo sapiens P07686
Y2H Pooling
32814053
Intra MKRN3 Q13064 HEXB Homo sapiens P07686
Validated Y2H
32814053
Intra MKRN3 Q13064 HEXB Homo sapiens P07686
Y2H Array
32814053
Intra MKRN3 Q13064 ANTKMT Homo sapiens Q9BQD7
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ANTKMT Homo sapiens Q9BQD7
Y2H Array
32296183
Intra MKRN3 Q13064 ANTKMT Homo sapiens Q9BQD7
Validated Y2H
32296183
Intra MKRN3 Q13064 INO80B Homo sapiens Q9C086
Validated Y2H
32296183
Intra MKRN3 Q13064 MAGED1 Homo sapiens Q9Y5V3
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 MAGED1 Homo sapiens Q9Y5V3
Validated Y2H
32296183
Intra MKRN3 Q13064 MAGED1 Homo sapiens Q9Y5V3
Y2H Array
32296183
Intra MKRN3 Q13064 MRPS6 Homo sapiens P82932
Y2H Array
25416956
Intra MKRN3 Q13064 MRPS6 Homo sapiens P82932
Validated Y2H
25416956
Intra MKRN3 Q13064 MRPL38 Homo sapiens Q96DV4
Validated Y2H
32296183
Intra MKRN3 Q13064 MRPL38 Homo sapiens Q96DV4
Y2H Array
32296183
Intra MKRN3 Q13064 MRPL38 Homo sapiens Q96DV4
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 STMN3 Homo sapiens Q9NZ72
Validated Y2H
32296183
Intra MKRN3 Q13064 STMN3 Homo sapiens Q9NZ72
Y2H Array
32296183
Intra MKRN3 Q13064 STMN3 Homo sapiens Q9NZ72
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 TCL1B Homo sapiens O95988
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 TCL1B Homo sapiens O95988
Y2H Array
32296183
Intra MKRN3 Q13064 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra MKRN3 Q13064 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
32296183
Intra MKRN3 Q13064 CRACR2A Homo sapiens Q9BSW2
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 CRACR2A Homo sapiens Q9BSW2
Y2H Array
25416956
Intra MKRN3 Q13064 USHBP1 Homo sapiens Q8N6Y0
Validated Y2H
32296183
Intra MKRN3 Q13064 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 HOXA1 Homo sapiens P49639
Y2H Array
32296183
Intra MKRN3 Q13064 CCDC185 Homo sapiens Q8N715
Validated Y2H
32296183
Intra MKRN3 Q13064 RASD1 Homo sapiens Q9Y272
Validated Y2H
32296183
Intra MKRN3 Q13064 SORBS3 Homo sapiens O60504
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 SORBS3 Homo sapiens O60504
Y2H Array
32296183
Intra MKRN3 Q13064 FAM124B Homo sapiens Q9H5Z6
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 FAM124B Homo sapiens Q9H5Z6
Y2H Array
25416956
Intra MKRN3 Q13064 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Intra MKRN3 Q13064 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
Intra MKRN3 Q13064 TADA2A Homo sapiens O75478
Y2H Array
32296183
Intra MKRN3 Q13064 TADA2A Homo sapiens O75478
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 APEX2 Homo sapiens Q9UBZ4
Validated Y2H
32296183
Intra MKRN3 Q13064 BATF2 Homo sapiens Q8N1L9
Y2H Array
32296183
Intra MKRN3 Q13064 BATF2 Homo sapiens Q8N1L9
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 BATF2 Homo sapiens Q8N1L9
Validated Y2H
32296183
Intra MKRN3 Q13064 UBE2D1 Homo sapiens P51668
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 UBE2D1 Homo sapiens P51668
Y2H Array
19549727
Intra MKRN3 Q13064 ENKD1 Homo sapiens Q9H0I2
Validated Y2H
25416956
Intra MKRN3 Q13064 ENKD1 Homo sapiens Q9H0I2
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 ENKD1 Homo sapiens Q9H0I2
Y2H Array
25416956
Intra MKRN3 Q13064 ZNF414 Homo sapiens Q96IQ9
Validated Y2H
32296183
Intra MKRN3 Q13064 CCDC120 Homo sapiens Q96HB5
Validated Y2H
32296183
Intra MKRN3 Q13064 SF1 Homo sapiens Q15637
Validated Y2H
25416956
Intra MKRN3 Q13064 SF1 Homo sapiens Q15637
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 NME4 Homo sapiens O00746
Y2H Array
32296183
Intra MKRN3 Q13064 NME4 Homo sapiens O00746
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 BEX2 Homo sapiens Q9BXY8
Y2H Array
25416956
Intra MKRN3 Q13064 BEX2 Homo sapiens Q9BXY8
Validated Y2H
25416956
Intra MKRN3 Q13064 BEX2 Homo sapiens Q9BXY8
Validated Y2H
32296183
Intra MKRN3 Q13064 ATOSB Homo sapiens Q7L5A3
Validated Y2H
32296183
Intra MKRN3 Q13064 TASOR2 Homo sapiens Q5VWN6
Validated Y2H
32296183
Intra MKRN3 Q13064 MYOZ2 Homo sapiens Q9NPC6
Validated Y2H
32296183
Intra MKRN3 Q13064 MYOZ2 Homo sapiens Q9NPC6
Y2H Array
32296183
Intra MKRN3 Q13064 MYOZ2 Homo sapiens Q9NPC6
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 STN1 Homo sapiens Q9H668
Validated Y2H
32296183
Intra MKRN3 Q13064 STN1 Homo sapiens Q9H668
Y2H Array
32296183
Intra MKRN3 Q13064 STN1 Homo sapiens Q9H668
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 IKZF3 Homo sapiens Q9UKT9
Y2H Array
32296183
Intra MKRN3 Q13064 IKZF3 Homo sapiens Q9UKT9
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 IKZF3 Homo sapiens Q9UKT9
Validated Y2H
32296183
Intra MKRN3 Q13064 SCNM1 Homo sapiens Q9BWG6
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 SCNM1 Homo sapiens Q9BWG6
Validated Y2H
32296183
Intra MKRN3 Q13064 TXNDC11 Homo sapiens Q6PKC3
Validated Y2H
32296183
Intra MKRN3 Q13064 TXNDC11 Homo sapiens Q6PKC3
Y2H Array
32296183
Intra MKRN3 Q13064 TXNDC11 Homo sapiens Q6PKC3
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ERCC1 Homo sapiens P07992
Validated Y2H
25416956
Intra MKRN3 Q13064 ERCC1 Homo sapiens P07992
Y2H Prey Pooling
25416956
Intra MKRN3 Q13064 TENT5B Homo sapiens Q96A09
Y2H Array
32296183
Intra MKRN3 Q13064 TENT5B Homo sapiens Q96A09
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 TENT5B Homo sapiens Q96A09
Validated Y2H
32296183
Intra MKRN3 Q13064 KLF1 Homo sapiens Q13351
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 KLF1 Homo sapiens Q13351
Validated Y2H
32296183
Intra MKRN3 Q13064 KLF1 Homo sapiens Q13351
Y2H Array
32296183
Intra MKRN3 Q13064 SPATA8 Homo sapiens Q6RVD6
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 SPATA8 Homo sapiens Q6RVD6
Validated Y2H
32296183
Intra MKRN3 Q13064 SPATA8 Homo sapiens Q6RVD6
Y2H Array
32296183
Intra MKRN3 Q13064 AVPI1 Homo sapiens Q5T686
Validated Y2H
32296183
Intra MKRN3 Q13064 AVPI1 Homo sapiens Q5T686
Y2H Array
32296183
Intra MKRN3 Q13064 AVPI1 Homo sapiens Q5T686
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 TSPAN4 Homo sapiens O14817
Y2H Array
32296183
Intra MKRN3 Q13064 TSPAN4 Homo sapiens O14817
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 VPS9D1 Homo sapiens Q9Y2B5
Validated Y2H
32296183
Intra MKRN3 Q13064 LASP1 Homo sapiens Q14847-2
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 LASP1 Homo sapiens Q14847-2
Validated Y2H
32296183
Intra MKRN3 Q13064 LASP1 Homo sapiens Q14847-2
Y2H Array
32296183
Intra MKRN3 Q13064 GATA1 Homo sapiens P15976-2
Y2H Array
32296183
Intra MKRN3 Q13064 GATA1 Homo sapiens P15976-2
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 TTC23 Homo sapiens Q5W5X9-3
Validated Y2H
32296183
Intra MKRN3 Q13064 MIF4GD Homo sapiens A9UHW6-2
Y2H Array
32296183
Intra MKRN3 Q13064 MIF4GD Homo sapiens A9UHW6-2
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ECM1 Homo sapiens Q16610
Y2H Array
32296183
Intra MKRN3 Q13064 ECM1 Homo sapiens Q16610
Validated Y2H
32296183
Intra MKRN3 Q13064 ECM1 Homo sapiens Q16610
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ARID5A Homo sapiens Q03989
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 ARID5A Homo sapiens Q03989
Y2H Array
32296183
Intra MKRN3 Q13064 BPIFA1 Homo sapiens Q9NP55
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 BPIFA1 Homo sapiens Q9NP55
Validated Y2H
32296183
Intra MKRN3 Q13064 BPIFA1 Homo sapiens Q9NP55
Y2H Array
32296183
Intra MKRN3 Q13064 MORN3 Homo sapiens Q6PF18
Y2H Prey Pooling
32296183
Intra MKRN3 Q13064 MORN3 Homo sapiens Q6PF18
Validated Y2H
32296183
Intra MKRN3 Q13064 MORN3 Homo sapiens Q6PF18
Y2H Array
32296183
Intra MKRN3 Q13064 KRT86 Homo sapiens O43790
Y2H Array
32296183
Intra MKRN3 Q13064 KRT86 Homo sapiens O43790
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Precocious Puberty, Central, 2

CPPB2

Central Precocious Puberty 2

Precocious Puberty, Central 2

Precocious Puberty, Central, Type 2
Idiopathic Central Precocious Puberty
Prader-Willi Syndrome

Prader-Labhart-Willi Syndrome

PWS

Willi-Prader Syndrome

Prader-Willi Syndrome Due To Translocation

Prader-Willi Syndrome Due To Imprinting Mutation

Prader-Willi Syndrome Due To Maternal Uniparental Disomy Of Chromosome 15

Prader Willi Syndrome

Upd(15)Mat
Central Precocious Puberty

Cpp

Gonadotropin-Dependant Precocious Puberty

Gonadotropin-Dependent Precocious Puberty

Precocious Puberty, Central
Precocious Puberty

Familial Precocious Puberty

Idiopathic Sexual Precocity

Sexual Precocity

Puberty Precocious

Cryptogenic Sexual Precocity
Angelman Syndrome

AS

Happy Puppet Syndrome

Happy Puppet Syndrome, Formerly

Puppetlike Syndrome
Temple Syndrome

Uniparental Disomy, Maternal, Chromosome 14

Temple Syndrome Due To Paternal 14q32.2 Microdeletion

Paternal Del(14)(Q32.2)

Temple Syndrome Due To Paternal 14q32.2 Hypomethylation

Temple Syndrome Due To Maternal Uniparental Disomy Of Chromosome 14

Upd(14)Mat
Precocious Puberty, Male-Limited

Testotoxicosis

Familial Male-Limited Precocious Puberty

Leydig Cell Adenoma, Somatic, With Precocious Puberty

FMPP

Familial Testotoxicosis

Sexual Precocity, Familial, Gonadotropin-Independent

Familial Gonadotropin-Independent Male-Limited Sexual Precocity

Male-Limited Precocious Puberty

Pubertas Praecox

Gonadotropin-Independent Familial Sexual Precocity

Testotoxicosis, Familial

Precocious Puberty, Male

Precocious Puberty, Male Limited

Familial Gonadotrophin-Independent Sexual Precocity

Gipp

Gonadotrophin-Independent Precocious Puberty

Precocious Pseudopuberty

Familial Male Precocious Puberty

Precocious Puberty In Males

Puberty, Precocious

Precocious Puberty
Schaaf-Yang Syndrome

Prader-Willi-Like Syndrome

Chitayat-Hall Syndrome

SHFYNG

Pwls

Magel2-Related Prader-Willi-Like Syndrome

Magel2-Related Pwls

Arthrogryposis, Distal, With Hypopituitarism, Mental Retardation, And Facial Anomalies

Distal Arthrogryposis With Hypopituitarism, Intellectual Disability And Facial A

Distal Arthrogryposis With Hypopituitarism, Intellectual Disability And Facial Anomalies

Pws Due To A Point Mutation

Pws Due To Point Mutation

Prader-Willi Syndrome Due To A Point Mutation

Prader-Willi Syndrome Due To Point Mutation

Pws-Like
Hypogonadotropic Hypogonadism

Klinefelter Syndrome

Klinefelter'S Syndrome

Xxy Syndrome

Xxy Trisomy

Hypogonadotropism

47, Xxy

Congenital Idiopathic Hypogonadotropic Hypogonadism

Isolated Congenital Gonadotropin Deficiency

47,Xxy Syndrome

47, Xxy Syndrome

Klinefelters Syndrome

Hypogonadism

Klinefelter Syndrome In Males

Klinefelter Syndrome, Unspecified

Klinefelter Syndrome Karyotype 47, Xxy
Chromosomal Disease

Chromosomal Disorders

Congenital Chromosomal Disease
Intrauterine Growth Retardation, Metaphyseal Dysplasia, Adrenal Hypoplasia Congenita, And Genital Anomalies

Image Syndrome

IMAGE

Intrauterine Growth Retardation-Metaphyseal Dysplasia-Adrenal Hypoplasia Congenita-Genital Anomalies Syndrome

Intrauterine Growth Restriction, Metaphyseal Dysplasia, Adrenal Hypoplasia Congenita, And Genital Anomalies

Intrauterine Growth Restriction, Metaphyseal Dysplasia, Adrenal Hypoplasia Congenita, Genital Abnormalities

Intrauterine Growth Restriction, Metaphyseal Dysplasia, Adrenal Hypoplasia Congenita, Genital Anomalies

Image Anomaly

Image Association

Fetal Growth Retardation

Pyle Metaphyseal Dysplasia
Esotropia

Convergence In Manifest Squint

Crossed Eyes

Internal Strabismus

Convergent Concomitant Strabismus

Convergent Squint

Convergent Strabismus

Cross-Eye
Kagami-Ogata Syndrome

Paternal Uniparental Disomy Of Chromosome 14

Uniparental Disomy, Paternal, Chromosome 14

Kos

Mca Due To 14q32.2 Maternally Expressed Gene Defect

Paternal Uniparental Disomy 14

Kagami-Ogata Syndrome Due To Maternal 14q32.2 Microdeletion

Maternal Del(14)(Q32.2)

Maternal Monosomy 14q32.2

Kagami-Ogata Syndrome Due To Maternal 14q32.2 Hypermethylation

Kagami-Ogata Syndrome Due To Paternal Uniparental Disomy Of Chromosome 14

Upd(14)Pat
Premature Menopause

Primary Ovarian Insufficiency

Premature Ovarian Failure

Hypergonadotropic Hypogonadism

Premature Ovarian Insufficiency

Menopause - Premature

Menopause Praecox

Menopause Premature

Menopause, Premature

Female Hypergonadotropic Hypogonadism

Hypergonadotrophic Ovarian Failure

Primary Female Hypogonadism

Pof - [Premature Ovarian Failure]

Ovarian Failure

Ovarian Secretion Suppression

Ovary Hyposecretion

Ovary Secretion Deficiency

Premature Menopause Nos
Cryptorchidism, Unilateral Or Bilateral

Cryptorchidism

Undescended Testicle

Undescended Testis

Cryptorchism

Undescended Testicles

CRYPTO

Impaired Testicular Descent

Cryptosporidiosis

Retained Testis

Unilateral Cryptorchidism

Unilateral Undescended Testis

Nondescent Unilateral Testicle

Unilateral Cryptorchism

Ectopic Testis, Unilateral

Bilateral Cryptorchidism

Bilateral Cryptorchism

Bilateral Nondescent Testicle

Bilateral Undescended Testes

Bilateral Ectopic Testes
Beckwith-Wiedemann Syndrome

Wiedemann-Beckwith Syndrome

BWS

Exomphalos-Macroglossia-Gigantism Syndrome

Emg Syndrome

Beckwith-Wiedemann Syndrome Due To Cdkn1c Mutation

Emg Abnormality

Wbs

Exomphalos Macroglossia Gigantism Syndrome

Beckwith-Wiedemann Syndrome Due To Nsd1 Mutation

Macroglossia Exomphalos Gigantism
Strabismus

Strabismus, Susceptibility To

Strabismus, Susceptibility To, 1

Strabismus 1
Kallmann Syndrome

Hypogonadism With Anosmia

Kallman'S Syndrome

Anosmic Hypogonadism

Anosmic Idiopathic Hypogonadotropic Hypogonadism

Hypogonadotropic Hypogonadism And Anosmia

Hypogonadotropic Hypogonadism-Anosmia Syndrome

Olfacto-Genital Pathological Sequence

Familial Hypogonadism With Anosmia

Kallman Syndrome

Dysplasia Olfactogenitalis Of De Morsier

Kallmann'S Syndrome

Congenital Hypogonadotropic Hypogonadism With Anosmia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08481 MKRN3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MKRN3 RGD RGD:1311197
Canis familiaris MKRN3 VGNC VGNC:43253
Mus musculus MKRN3 MGD MGI:2181178
Others MKRN3 NCBI