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Results for "

Folate

" in MedChemExpress (MCE) Product Catalog:

122

Inhibitors & Agonists

2

Fluorescent Dye

23

Biochemical Assay Reagents

5

Peptides

3

Inhibitory Antibodies

13

Natural
Products

19

Recombinant Proteins

8

Isotope-Labeled Compounds

1

Antibodies

6

Click Chemistry

11

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-47373

    PROTAC Linkers Cancer
    Folate-PEG3-C2-acid is the acid fragment of Folate-PEG3-NHS ester (HY-133493), which belongs to the PEG-type PROTAC linker and is used to synthesize PROTAC molecules.
    Folate-PEG3-C2-acid
  • HY-138484

    ADC Linker Cancer
    Folate-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
    Folate-PEG3-amine
  • HY-W440888

    DSPE-PEG(2000) Folate

    Liposome Others
    DSPE-PEG-Folate, MW 2000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 2000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 2000 form micelles/lipid bilayer and can be used to targeted drug delivery system research.
    DSPE-PEG-Folate, MW 2000
  • HY-115873

    PROTACs Cancer
    Folate-MS432, a PROTAC, is capable of degrading MEKs in a folate receptor-dependent manner in cancer cells.
    Folate-MS432
  • HY-13615

    EC-17

    Fluorescent Dye Others Cancer
    Folate-FTIC (EC-17) is a folic acid derivative that binds to fluorescein isothiocyanate (FITC) to give it fluorescent labeling properties. Folate-ftic is used to induce the formation of pseudo-immunological synapses between anti-FITC CAR T cells and target cells expressing Folate receptors (FRα or FRβ). Folate-FTIC can be used to develop controlled CAR-T cell therapies for research in non-small cell lung cancer (NSCLC) .
    Folate-FTIC
  • HY-133496

    PROTAC Linkers Cancer
    Folate-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Folate-PEG3-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Folate-PEG3-alkyne
  • HY-133494

    PROTAC Linkers Cancer
    Folate-PEG1-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Folate-PEG1-mal
  • HY-133495

    PROTAC Linkers Cancer
    Folate-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Folate-PEG2-amine
  • HY-133493

    PROTAC Linkers Cancer
    Folate-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    Folate-PEG3-NHS ester
  • HY-122378

    Pteroyl diglutamic acid; Folate monoglutamate

    Antifolate Cancer
    Diopterin is a folic acid analog that is used in leukemia research .
    Diopterin
  • HY-133383

    PROTAC Linkers Cancer
    DSPE-PEG46-Folate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    DSPE-PEG46-Folate
  • HY-126806

    Antibiotic Cancer
    Pyrrofolic acid is a folate antagonist with a low activity as a folate antagonist for Streptococcus faecalis .
    Pyrrofolic acid
  • HY-144009

    Liposome Cancer
    DSPE-PEG-Folate, MW 3350 is a PEG derivative containing folic acid. DSPE-PEG-Folate has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate form micelles/lipid bilayer and can be used to targeted drug delivery system research .
    DSPE-PEG-Folate, MW 3350
  • HY-W440890

    Liposome Cancer
    DSPE-PEG-Folate, MW 5000 is a PEG derivative containing folic acid. DSPE-PEG-Folate, MW 5000 has a targeting effect and bind to folate receptors in cancer cells. DSPE-PEG-Folate, MW 5000 form micelles/lipid bilayer and can be used to targeted drug delivery system research .
    DSPE-PEG-Folate, MW 5000
  • HY-W440715

    Liposome Others
    Cholesterol-PEG-Folate, MW 2000 is an excipient and can be used for the preparation of folate-conjugated PEG-liposomes .
    Cholesterol-PEG-Folate, MW 2000
  • HY-W440714

    Biochemical Assay Reagents Others
    Cholesterol-PEG-Folate (MW 1000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 1000) can be used in drug delivery research .
    Cholesterol-PEG-Folate (MW 1000)
  • HY-W440716

    Biochemical Assay Reagents Others
    Cholesterol-PEG-Folate (MW 3400) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 3400) can be used in drug delivery research .
    Cholesterol-PEG-Folate (MW 3400)
  • HY-W440717

    Biochemical Assay Reagents Others
    Cholesterol-PEG-Folate (MW 5000) is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG-Folate (MW 5000) can be used in drug delivery research .
    Cholesterol-PEG-Folate (MW 5000)
  • HY-127118

    Pteroyltriglutamic

    Drug Metabolite Cancer
    Pteropterin (Pteroyltriglutamic) is an active form of folate. Pteropterin shows inhibiting effect on tumor growth and has broad anticancer activity .
    Pteropterin
  • HY-127118A

    Pteroyltriglutamic monohydrate

    Drug Metabolite Folate Receptor (FR) Cancer
    Pteropterin (Pteroyltriglutamic) monohydrate is an active form of folate. Pteropterin monohydrate shows inhibiting effect on tumor growth and has broad anticancer activity .
    Pteropterin monohydrate
  • HY-121927

    CH-1504

    Antifolate Dihydrofolate reductase (DHFR) Inflammation/Immunology
    Mobiletrex is an anti folate and dihydrofolate reductase inhibitor that can be used in research on rheumatoid arthritis .
    Mobiletrex
  • HY-W037823

    Biochemical Assay Reagents Others
    Pterin-6-carboxylic acid serves as a precursor for the formation of folate, which plays a critical role in cell growth, development, and repair. Pterine-6-carboxylic acid has been studied for its potential as a fluorescent dye .
    Pterin-6-carboxylic acid
  • HY-10822A

    BGC 945 trisodium; Idetrexed trisodium; CB 300945 trisodium

    Thymidylate Synthase Cancer
    ONX 0801 (BGC 945) trisodium is a thymidylate synthase (TS) inhibitor, targeted to α-folate receptor–overexpressing tumors .
    ONX 0801 trisodium
  • HY-137267

    Antifolate Cancer
    10-Methyl-10-deazaaminopterin is a folate analog and an antifolate. 10-Methyl-10-deazaaminopterin can be used for the research of cancer .
    10-Methyl-10-deazaaminopterin
  • HY-109051

    Endogenous Metabolite Cancer
    Arfolitixorin is a potent 5-Fluorouracil (5-FU) moderator. Arfolitixorin is an immediately active form of Folate, [6R]-5,10-methylenetetrahydrofolate ([6R]-MTHF). Arfolitixorin is potent for the research of metastatic colorectal cancer .
    Arfolitixorin
  • HY-109051C

    Endogenous Metabolite Cancer
    Arfolitixorin sulfate is a potent 5-Fluorouracil (5-FU) moderator. Arfolitixorin sulfate is an immediately active form of Folate, [6R]-5,10-methylenetetrahydrofolate ([6R]-MTHF). Arfolitixorin sulfate is potent for the research of metastatic colorectal cancer .
    Arfolitixorin sulfate
  • HY-13728

    ZD 9331; BGC9331

    Thymidylate Synthase Cancer
    Plevitrexed (ZD 9331; BGC 9331) is an orally active and potent thymidylate synthase (TS) inhibitor with a Ki of 0.44 nM. Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is used for gastric cancer in clinical . Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Plevitrexed
  • HY-147699

    Antifolate Cancer
    FRα-IN-1 (Compound 4) is a tumor-targeting agent. FRα-IN-1 shows selective anticancer activity towards folate receptors (FRα and FRβ) expression cells .
    FRα-IN-1
  • HY-124093

    Thymidylate Synthase Bacterial Infection Cancer
    8-Deazahomofolic acid is an inhibitor of thymidylate synthase (TS) and other folate-related enzymes. 8-Deazahomofolic acid shows inhibitory activity against folate-dependent S. faecium, L. casei, and MTX (HY-14519) resistant strains. 8-Deazahomofolic acid also inhibits the growth of L1210 leukemia cells, with an IC50 value of 87.5 μM. 8-Deazahomofolic acid can be used in research on bacterial infections and tumors .
    8-Deazahomofolic acid
  • HY-121256

    Thymidylate Synthase Antifolate Dihydrofolate reductase (DHFR) Others
    Chlorasquin inhibits thymidylate synthetase with an approximate Ki value of 4.9 μM. Chlorasquin is also a folate antagonist, testing the Methotrexate (HY-14519) effect. Chlorasquin binds tighter to dihydrofolate reductase at alkaline pH than does Methotrexate, which is promising for research of antipsoriatic agents .
    Chlorasquin
  • HY-W040821
    DL-Homocysteine
    2 Publications Verification

    Endogenous Metabolite Neurological Disease
    DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. DL-Homocysteine is correlated with Vitamin B12, renal functions and folate levels, affects the cross-sectional cognition indirectly through white matter microstructural integrity .
    DL-Homocysteine
  • HY-167411

    Biochemical Assay Reagents Others
    PLLA5000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA5000-PEG5000-FOL can be used in drug delivery research .
    PLLA5000-PEG5000-FOL
  • HY-167412

    Biochemical Assay Reagents Others
    PLLA5000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA5000-PEG2000-FOL can be used in drug delivery research .
    PLLA5000-PEG2000-FOL
  • HY-167413

    Biochemical Assay Reagents Others
    PLLA20000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA20000-PEG5000-FOL can be used in drug delivery research .
    PLLA20000-PEG5000-FOL
  • HY-167414

    Biochemical Assay Reagents Others
    PLLA20000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA20000-PEG2000-FOL can be used in drug delivery research .
    PLLA20000-PEG2000-FOL
  • HY-167415

    Biochemical Assay Reagents Others
    PLLA10000-PEG5000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA10000-PEG5000-FOL can be used in drug delivery research .
    PLLA10000-PEG5000-FOL
  • HY-167416

    Biochemical Assay Reagents Others
    PLLA10000-PEG2000-FOL is a polylactic acid derivative. Polylactic acid derivatives have strong binding affinity to folate receptors and clear biodegradability. PLLA10000-PEG2000-FOL can be used in drug delivery research .
    PLLA10000-PEG2000-FOL
  • HY-B1497

    AgSD

    Bacterial DNA/RNA Synthesis Antibiotic Infection
    Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication .
    Silver sulfadiazine
  • HY-P10501

    Antifolate Cancer
    FRα-targeting peptide C7 is a selective peptide ligand for folate receptor α (FRα) that has specific binding to FRα expressing cells and in vivo tumor targeting ability. FRα-targeting peptide C7 can be used in the research of tumor diagnosis and treatment .
    FRα-targeting peptide C7
  • HY-P99153

    MORAb-003

    Antibiotic Cancer
    Farletuzumab (MORAb-003) is a potent folate receptor-alpha (FRα) inhibitor. Farletuzumab is a humanized monoclonal antibody with high affinity for FRα. Farletuzumab possesses growth-inhibitory functions on cells overexpressing FRα. Farletuzumab can be used in research of cancer .
    Farletuzumab
  • HY-B1497R

    Bacterial DNA/RNA Synthesis Antibiotic Infection
    Silver sulfadiazine (Standard) is the analytical standard of Silver sulfadiazine. This product is intended for research and analytical applications. Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication .
    Silver sulfadiazine (Standard)
  • HY-10824

    PT523

    Antifolate Dihydrofolate reductase (DHFR) Cancer
    Talotrexin (PT523), an analog of Aminopterin (HY-14518), is a nonpolyglutamatable classic antifolate. Talotrexin is a RFC (reduced folate carrier) specific inhibitor and selectively inhibits RFC transport. Talotrexin shows antitumor activity by targeting DHFR to inhibit tumor growth .
    Talotrexin
  • HY-14520
    Tetrahydrofolic acid
    3 Publications Verification

    L-5,6,7,8-Tetrahydrofolic acid; L-Tetrahydrofolic acid

    Endogenous Metabolite Metabolic Disease
    Tetrahydrofolic acid (L-5,6,7,8-Tetrahydrofolic acid) is the biologically active vitamin B9 folate derivative. Tetrahydrofolic acid is a donor of one-carbon groups for amino acids, nucleic acids, and lipids. Tetrahydrofolic acid serves as an acceptor of free formaldehyde, producing 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid .
    Tetrahydrofolic acid
  • HY-14520B

    L-5,6,7,8-Tetrahydrofolic acid trihydrochloride; L-Tetrahydrofolic acid trihydrochloride

    Endogenous Metabolite Metabolic Disease
    Tetrahydrofolic acid (L-5,6,7,8-Tetrahydrofolic acid) trihydrochloride is the biologically active vitamin B9 folate derivative. Tetrahydrofolic acid trihydrochloride is a donor of one-carbon groups for amino acids, nucleic acids, and lipids. Tetrahydrofolic acid trihydrochloride serves as an acceptor of free formaldehyde, producing 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid .
    Tetrahydrofolic acid trihydrochloride
  • HY-10824A

    PT523 monoammonium

    Dihydrofolate reductase (DHFR) Antifolate Cancer
    Talotrexin monoammonium is the monoammonium salt form of Talotrexin (HY-10824). Talotrexin monoammonium is an analog of Aminopterin (HY-14518), and is a nonpolyglutamatable classic antifolate. Talotrexin monoammonium is a reduced folate carrier (RFC) specific inhibitor and selectively inhibits RFC transport. Talotrexin monoammonium shows antitumor activity by targeting DHFR to inhibit tumor growth .
    Talotrexin monoammonium
  • HY-P99612

    MORAb-202

    Antibody-Drug Conjugates (ADCs) Cancer
    Farletuzumab ecteribulin (MORAb-202) is an antibody-drug conjugate (ADC), consisting of the humanized anti-human folate receptor alpha (FRA) antibody Farletuzumab (HY-P99153) conjugated via reduced interchain disulfide bonds to Mal-PEG2-Val-Cit-PAB-eribulin. Farletuzumab ecteribulin has a agent-to-antibody ratio of 4.0. Farletuzumab ecteribulin is highly cytotoxic to FRA-positive cells in vitro. Farletuzumab ecteribulin has potent antitumor activity.
    Farletuzumab ecteribulin
  • HY-155880

    mPEG-NH2 (MW 350)

    Biochemical Assay Reagents Cancer
    mPEG-amine (MW 350) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
    mPEG-amine (MW 350)
  • HY-155881

    mPEG-NH2 (MW 550)

    Biochemical Assay Reagents Cancer
    mPEG-amine (MW 550) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
    mPEG-amine (MW 550)
  • HY-155882

    mPEG-NH2 (MW 750)

    Biochemical Assay Reagents Cancer
    mPEG-amine (MW 750) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
    mPEG-amine (MW 750)
  • HY-155883

    mPEG-NH2 (MW 3400)

    Biochemical Assay Reagents Cancer
    mPEG-amine (MW 3400) can synthesize folate-conjugated polymer micelles for encapsulation of anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR).
    mPEG-amine (MW 3400)

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