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RDC

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Apoptosis (1) Autophagy (1) HIF/HIF Prolyl-Hydroxylase (1) Isotope-Labeled Compounds (1) Opioid Receptor (1) Radionuclide-Drug Conjugates (RDCs) (2) Reactive Oxygen Species (1)
By Research Areas:	Cancer (2) Neurological Disease (2)

Inhibitors & Agonists

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-123689

Samidorphan ALKS-33; RDC-0313	Opioid Receptor	Neurological Disease
Samidorphan (ALKS-33) is an orally active opioid system modulator that has a high affinity for binding with μ‐opioid, κ‐opioid, and δ‐opioid receptors. Samidorphan acts as an antagonist at μ‐opioid receptors and acts as a partial agonist at k-opioid and δ‐opioid receptors. Samidorphan primarily acts as an opioid receptor antagonist in vivo .

HY-132989

Mal-Deferoxamine	Reactive Oxygen Species Apoptosis Autophagy HIF/HIF Prolyl-Hydroxylase Akt Radionuclide-Drug Conjugates (RDCs)	Cancer
Mal-Deferoxamine is a maleamide (Mal)-containing Deferoxamine (HY-B1625). Mal selectively covalently binds to sulfur groups to produce a linking reaction. Mal-Deferoxamine can be combined with radionuclides to synthesize radionuclide drug conjugates (RDCs). RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy. .

HY-123689S

Samidorphan-d4 ALKS-33-d₄; RDC-0313-d₄	Isotope-Labeled Compounds	Neurological Disease
Samidorphan-d4 is the deuterium labeled Samidorphan(HY-123689).Samidorphan (ALKS-33) is an orally active opioid system modulator that has a high affinity for binding with μ‐opioid, κ‐opioid, and δ‐opioid receptors. Samidorphan acts as an antagonist at μ‐opioid receptors and acts as a partial agonist at k-opioid and δ‐opioid receptors. Samidorphan primarily acts as an opioid receptor antagonist in vivo .

HY-W087028

NOTA-NHS ester	Radionuclide-Drug Conjugates (RDCs) Others	Cancer
NOTA-NHS ester is a molecule related to radiolabeling drugs (RDC) that can be used for fluorescent labeling and radioactive nuclide labeling applications .

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HY-P700537

	ACKR3 Protein, Human (His-SUMO) RDC1; CXCR7; RDC-1; CMKOR1; CXC-R7; CXCR-7; GPR159	Human	E. coli
	ACKR3, an atypical chemokine receptor, precisely controls chemokine levels and localization through high-affinity binding, operating independently of ligand-driven signal transduction. It serves as an interceptor, internalizing receptor, and chemokine-scavenger for CXCL11 and CXCL12/SDF1, inducing beta-arrestin recruitment, ligand internalization, and MAPK pathway activation. Essential for regulating CXCR4 in interneurons and promoting survival in glioma cells, ACKR3 also influences malignant hematopoietic cell adhesion and migration. Its regulatory roles extend to heart valve development, axon guidance, and HIV infection collaboration with CXCR4. ACKR3 Protein, Human (His-SUMO) is the recombinant human-derived ACKR3 protein, expressed by E. coli, with N-SUMO, N-6*His labeled tag. The total length of ACKR3 Protein, Human (His-SUMO) is 40 a.a., with molecular weight of 20.5 kDa.

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Cat. No.	Product Name	Chemical Structure

HY-123689S

Samidorphan-d4
Samidorphan-d4 is the deuterium labeled Samidorphan(HY-123689).Samidorphan (ALKS-33) is an orally active opioid system modulator that has a high affinity for binding with μ‐opioid, κ‐opioid, and δ‐opioid receptors. Samidorphan acts as an antagonist at μ‐opioid receptors and acts as a partial agonist at k-opioid and δ‐opioid receptors. Samidorphan primarily acts as an opioid receptor antagonist in vivo .

Samidorphan-d4

Samidorphan-d4 is the deuterium labeled Samidorphan(HY-123689).Samidorphan (ALKS-33) is an orally active opioid system modulator that has a high affinity for binding with μ‐opioid, κ‐opioid, and δ‐opioid receptors. Samidorphan acts as an antagonist at μ‐opioid receptors and acts as a partial agonist at k-opioid and δ‐opioid receptors. Samidorphan primarily acts as an opioid receptor antagonist in vivo .

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HY-P83212

	RDC1 Antibody (YA2957) RDC1; CXCR7; RDC-1; CMKOR1; CXC-R7; CXCR-7; GPR159	WB	Human, Mouse, Rat
	RDC1 Antibody (YA2957) is a biotin-conjugated non-conjugated IgG antibody, targeting RDC1, with a predicted molecular weight of 41 kDa (observed band size: 41 kDa). RDC1 Antibody (YA2957) can be used for WB experiment in human, mouse, rat background.

HY-P81524

	VIPR1 Antibody (YA1269) vasoactive inTinal peptide receptor 1; II; HVR1; RDC1; V1RG; VIPR; VIRG; VAPC1; VPAC1; VPAC1R; VIP-R-1; VPCAP1R; PACAP-R2; PACAP-R-2	IHC-P	Human
	VIPR1 Antibody (YA1269) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1269), targeting VIPR1. VIPR1 Antibody (YA1269) can be used for IHC-P experiment in human background.

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