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Zinc Protoporphyrin-d<sub>2</sub>,<sup>15</sup>N<sub>2</sub>

" in MedChemExpress (MCE) Product Catalog:

100

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11

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1

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70

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2

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30

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101193
    Zinc Protoporphyrin
    Maximum Cited Publications
    40 Publications Verification

    Zn(II)-Protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9

    Reactive Oxygen Species Endogenous Metabolite Apoptosis Cardiovascular Disease Metabolic Disease Cancer
    Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .
    Zinc Protoporphyrin
  • HY-101194
    Tin protoporphyrin IX dichloride
    15+ Cited Publications

    Tin-Protoporphyrin IX; Sn-Protoporphyrin; SnPPIX

    Reactive Oxygen Species Cancer
    Tin protoporphyrin IX dichloride (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin protoporphyrin IX dichloride sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model .
    Tin protoporphyrin IX dichloride
  • HY-136476G

    Others Others
    Pt(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .
    Pt(II) protoporphyrin IX
  • HY-B1247
    Protoporphyrin IX
    10+ Cited Publications

    Endogenous Metabolite Others
    Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
    Protoporphyrin IX
  • HY-W250116

    Protoporphyrin IX cobaltic chloride

    Biochemical Assay Reagents Others
    Co(III) Protoporphyrin IX chloride (CoPP) is an effective HO-1inducer.
    Co(III) protoporphyrin IX chloride
  • HY-101193S

    Zn(II)-Protoporphyrin IX-d2,15N2; ZnPP-d2,15N2; Zinc Protoporphyrin-9-d2,15N2

    Apoptosis Endogenous Metabolite Reactive Oxygen Species Isotope-Labeled Compounds Cardiovascular Disease Metabolic Disease Cancer
    Zinc Protoporphyrin-d2, 15N2 is 15N and deuterated labeled Zinc Protoporphyrin (HY-101193). Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .
    Zinc Protoporphyrin-d2,15N2
  • HY-136476E

    Others Others
    Cr(III) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .
    Cr(III) protoporphyrin IX
  • HY-136476F

    Drug Intermediate Others
    Cd(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway .
    Cd(II) protoporphyrin IX
  • HY-B1247R

    Endogenous Metabolite Others
    Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
    Protoporphyrin IX (Standard)
  • HY-136476

    Others Others
    Mg(II) protoporphyrin IX is a precursor of chlorophyll in Chlorella. Mg(II) protoporphyrin IX is a negative effector of nuclear photosynthetic gene expression. Mg(II) protoporphyrin IX can be used for the research of signaling molecule implicated in plastid-to-nucleus communication .
    Mg(II) protoporphyrin IX
  • HY-136476A

    Biochemical Assay Reagents Others
    Mn(II) protoporphyrin IX is a potential intravenous paramagnetic magnetic resonance contrast agent. Mn(II) protoporphyrin IX maintains strong paramagnetic properties .
    Mn(II) protoporphyrin IX
  • HY-B1247A

    Endogenous Metabolite Cancer
    Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX disodium also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX disodium is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX disodium causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX disodium is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
    Protoporphyrin IX disodium
  • HY-W854721

    Manganese(III) Protoporphyrin IX Chloride

    Others Metabolic Disease
    Mn(III) protoporphyrin IX chloride is a metalloporphyrin. It induces mRNA expression of the genes encoding δ-aminolevulinate synthase and heme oxygenase (HO), enzymes that catalyze the rate-limiting steps of heme biosynthesis and degradation, respectively, in chick embryo liver cells when used at a concentration of 10 μM. Mn(III) protoporphyrin IX chloride-containing nanobialys have been used in magnetic resonance imaging (MRI) of fibrin clots in vitro. It has also been used in the synthesis of Mn(III) protoporphyrin IX-6(7)-glycyl-glycyl-L-histidine methyl ester (MnGGH), a metalloporphyrin conjugate with microperoxidase activity.
    Mn(III) Protoporphyrin IX chloride
  • HY-136476B

    Others Inflammation/Immunology Cancer
    Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair .
    Cu(II) protoporphyrin IX
  • HY-134608

    Co-PPIX

    Reactive Oxygen Species Influenza Virus Infection
    Cobalt protoporphyrin IX (Co-PPIX) is a potent and specific heme oxygenase-1 (HO-1) inducer. Cobalt protoporphyrin IX exhibits broad-spectrum antiviral activities against Influenza A virus (IAV) .
    Cobalt protoporphyrin IX
  • HY-133100

    Benzyl-ALA hydrochloride

    Endogenous Metabolite Cancer
    5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. 5-ALA benzyl ester hydrochloride induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines .
    5-ALA benzyl ester hydrochloride
  • HY-W127816

    Biochemical Assay Reagents Others
    Cr(III) Protoporphyrin IX Chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Cr(III) Protoporphyrin IX chloride
  • HY-136476C

    Others Others
    Ni(II) protoporphyrin IX is a metalloporphyrin that has a low tendency toward axial ligation, becomes distorted when bound to ferrochelatase .
    Ni(II) protoporphyrin IX
  • HY-108774

    Rosuvastatin Zinc

    HMG-CoA Reductase (HMGCR) Cardiovascular Disease Metabolic Disease
    Rosuvastatin zinc salt (Rosuvastatin zinc) is a zinc-containing form of Rosuvastatin (HY-17504A). Rosuvastatin is a HMG-CoA reductase inhibitor and can be used for atherosclerosis research .
    Rosuvastatin zinc salt
  • HY-21170E

    Zinc(II) Triflate

    Biochemical Assay Reagents Others
    Zinc trifluoromethanesulfonate (Zinc(II) Triflate) is a biological molecule.
    Zinc trifluoromethanesulfonate
  • HY-B0278

    Zinc bacitracin

    Bacterial Antibiotic Infection
    Bacitracin Zinc is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle .
    Bacitracin Zinc
  • HY-B0278R

    Zinc bacitracin (Standard)

    Bacterial Antibiotic Infection
    Bacitracin Zinc (Standard) is the analytical standard of Bacitracin Zinc (HY-B0278). Bacitracin Zinc (Standard) is a complex formed by the binding of Bacitracin (HY-107193) with zinc ions. Bacitracin Zinc (Standard) is an orally active polypeptide antibiotic with bactericidal properties. Bacitracin Zinc (Standard) can cause DNA and deoxyribose damage, as well as improve the gut microbiota of broiler and beef cattle .
    Bacitracin (Zinc) (Standard)
  • HY-115682

    Mas-related G-protein-coupled Receptor (MRGPR) Others
    (S)-ZINC-3573 is an inactive enantiomer of ZINC-3573. (R)-ZINC-3573 is a selective MRGPRX2 agonist. (S)-ZINC-3573 and (R)-ZINC3573 are effective and internally controlled probe-pairs for investigating the biology of primate-exclusive receptor .
    (S)-ZINC-3573
  • HY-N3025

    Others Metabolic Disease
    Zinc sulfate heptahydrate is a hydrate that is the heptahydrate form of zinc sulfate. Zinc sulfate heptahydrate is a dietary supplement used for zinc deficiency and to prevent the condition in those at high risk .
    Zinc sulfate heptahydrate
  • HY-134570
    ZINC40099027
    1 Publications Verification

    FAK Metabolic Disease
    ZINC40099027 is a FAK activator. ZINC40099027 promotes FAK phosphorylation, inducing mucosal healing in murine models. ZINC40099027 can be used for Gastroduodenal ulcer disease research .
    ZINC40099027
  • HY-N0157A
    Orotic acid zinc
    2 Publications Verification

    6-Carboxyuracil Zinc; Vitamin B13 Zinc

    Nucleoside Antimetabolite/Analog Endogenous Metabolite Metabolic Disease
    Orotic acid (zinc), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid (zinc) is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid (zinc) can induce hepatic steatosis and hepatomegaly in rats .
    Orotic acid zinc
  • HY-162321

    Ras Cancer
    ZINC57632462 (ACA-6) is a non-covalent allosteric KRAS inhibitor. ZINC57632462 disrupts nucleotide exchange and inhibits RAS-effector interaction. ZINC57632462 can be used for the research of cancer .
    ZINC57632462
  • HY-Y0939

    Zinc perchlorate hexahydrate

    Biochemical Assay Reagents Others
    Zinc diperchlorate hexahydrate (Zinc perchlorate hexahydrate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    Zinc diperchlorate hexahydrate
  • HY-146783

    PAK Cancer
    ZINC194100678 is a potent PAK1 inhibitor with an IC50 value of 8.37 μM. ZINC194100678 can inhibit MDA-MB-231 cell proliferation. ZINC194100678 can be used for researching anticancer .
    ZINC194100678
  • HY-168048

    Proteasome Cancer
    ZINC09518833 is a α-ketoamide nonpeptidic proteasome inhibitor with an IC50 value of 12.4 μM. ZINC09518833 binds both primed and nonprimed sites of the proteasome. ZINC09518833 is promising for research of multiple myeloma (MM) .
    ZINC09518833
  • HY-120465

    Others Infection
    ZINC36617540 is a novel Nef protein inhibitor with anti-HIV activity. ZINC36617540 exhibits superior binding affinity by binding to Nef protein. ZINC36617540 shows a similar binding mode to the prototype molecule B9 in molecular docking. The mechanism of action of ZINC36617540 mainly depends on its hydrophobic and electrostatic interactions with Nef protein .
    ZINC36617540
  • HY-B1817

    Biochemical Assay Reagents Others
    Zinc acetate, 99% is a biological molecule.
    Zinc acetate
  • HY-119287

    Fluorescent Dye Others
    TSQ is a cytosolic zinc ion fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λmax ~470 nm). TSQ can combine with Zn 2+ in the presence of Ca 2+ and Mg 2+ to produce blue fluorescence .
    TSQ
  • HY-B0914A
    10-Undecenoic acid zinc salt
    1 Publications Verification

    Zinc undecylenate

    Fungal DNA/RNA Synthesis Infection
    10-Undecenoic acid zinc salt is a RNA-dependent RNA polymerase (RdRp) inhibitor, with an IC50 of 1.13, 21.33 and 1.79 μM for WT-RdRp, D535ARdRp and D692A-RdRp, respectively. 10-Undecenoic acid zinc salt reduces infectious virus yield in Huh7 cells with an EC50 of 7.43 μM. 10-Undecenoic acid zinc salt has anti-infective and anti-fungal activity. 10-Undecenoic acid zinc salt can be used for the research of Zika virus (ZIKV) .
    10-Undecenoic acid zinc salt
  • HY-103061

    Cytochrome P450 Cardiovascular Disease
    Dehydro-ZINC39395747 is a derivative of ZINC39395747. ZINC39395747 is a potent cytochrome b5 reductase 3 (CYB5R3) inhibitor with an IC50 of 9.14 μM and a Kd of 1.11 μM. ZINC39395747 can increase NO bioavailability in vascular cells .
    Dehydro-ZINC39395747
  • HY-B0572R

    Cuproptosis Proton Pump Bacterial Fungal Infection Metabolic Disease
    Zinc Pyrithione (Standard) is the analytical standard of Zinc Pyrithione. This product is intended for research and analytical applications. Zinc Pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump . Zinc Pyrithione is also a copper ionophore that delivers copper into cells and is a useful tool for studying cuproptosis .
    Zinc Pyrithione (Standard)
  • HY-170542

    PARP Cancer
    ZINC20906412 is a poly(ADP-ribose) polymerase-10 (PARP10) inhibitor. ZINC20906412 can be used for the research of cancer .
    ZINC20906412
  • HY-148364

    Akt Cancer
    ZINC00784494 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00784494 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00784494 has good potential for research in inflammatory breast cancer (IBC) .
    ZINC00784494
  • HY-Q45780
    ZINC00640089
    2 Publications Verification

    Akt Cancer
    ZINC00640089 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00640089 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00640089 has good potential for research in inflammatory breast cancer (IBC) .
    ZINC00640089
  • HY-W099569

    Zinc octadecanoate

    Biochemical Assay Reagents Others
    Zinc stearate is a Zinc distearate. Zinc stearate can be used as an excipient, such as lubricants for tablets and capsules. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
    Zinc stearate
  • HY-157889

    HDAC Cancer
    ZINC000028464438 is a selective HDAC11 inhibitor with an IC50 of 3.5 µM. ZINC000028464438 shows almost no inhibition for other HDAC subtypes .
    ZINC000028464438
  • HY-123241

    Sirtuin Metabolic Disease Cancer
    ZINC08792229 is a potent SIRT1 inhibitor. ZINC08792229 has the potential for research on SIRT1 related diseases, such as ageing, diabetes, cancers .
    ZINC08792229
  • HY-W414898

    Biochemical Assay Reagents Others
    Zinc dihydrogen phosphate can be used as an analytical reagent and preservative. Zinc dihydrogen phosphate is a kind of biological materials or organic compounds that are widely used in life science research .
    Zinc dihydrogen phosphate
  • HY-169256

    SARS-CoV Infection
    ZINC4497834 is an inhibitor of SARS-CoV-2 major protease Mpro. ZINC4497834 can be used in anti-COVID19 research .
    ZINC4497834
  • HY-101244

    ROCK Cancer
    ZINC00881524 is a ROCK inhibitor.
    ZINC00881524
  • HY-W094709

    Biochemical Assay Reagents Others
    Zinc sulfate monohydrate is a biochemical reagent.
    Zinc sulfate monohydrate
  • HY-B1818

    Biochemical Assay Reagents Others
    Zinc monocarbonate is a biological molecule.
    Zinc carbonate
  • HY-B1820

    Biochemical Assay Reagents Others
    Zinc sulphate is a biological molecule.
    Zinc sulphate
  • HY-B1821

    Biochemical Assay Reagents Others
    Zinc monosulfide is a biological molecule.
    Zinc sulfide
  • HY-D0950A

    DNA Stain Others
    Methyl Green zinc chloride is a potent fluorescent dye. Methyl Green zinc chloride is a DNA stains of cells and electrophoretic gels. Methyl Green zinc chloride can be used as direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm .
    Methyl Green zinc chloride

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