Search Result

Results for "

Insecticidal activity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (1) Adrenergic Receptor (4) Akt (1) Antibiotic (10) Apoptosis (11) Autophagy (6) Bacterial (12) Bcl-2 Family (2) Biochemical Assay Reagents (5) Calcium Channel (1) Carboxylesterase (1) Caspase (3) CDK (1) Cholinesterase (ChE) (3) Cytochrome P450 (1) DNA/RNA Synthesis (1) EBV (1) Endogenous Metabolite (3) Fungal (11) GABA Receptor (8) HBV (1) HSP (1) Influenza Virus (1) Interleukin Related (2) Isotope-Labeled Compounds (5) MDM-2/p53 (1) Mitochondrial Metabolism (2) Monoamine Oxidase (4) Na+/K+ ATPase (1) nAChR (4) NF-κB (4) NO Synthase (1) P-glycoprotein (2) Parasite (39) Phosphatase (1) PI3K (1) PROTAC Linkers (1) Proton Pump (2) RAD51 (2) RANKL/RANK (1) Reactive Oxygen Species (4) Sodium Channel (5) TNF Receptor (2) Tyrosinase (1) β-catenin (2)
By Research Areas:	Cancer (25) Cardiovascular Disease (2) Endocrinology (4) Infection (74) Inflammation/Immunology (17) Metabolic Disease (2) Neurological Disease (16)

By Targets:

ADC Cytotoxin (1)

Adrenergic Receptor (4)

Akt (1)

Antibiotic (10)

Apoptosis (11)

Autophagy (6)

Bacterial (12)

Bcl-2 Family (2)

Biochemical Assay Reagents (5)

Calcium Channel (1)

Carboxylesterase (1)

Caspase (3)

CDK (1)

Cholinesterase (ChE) (3)

Cytochrome P450 (1)

DNA/RNA Synthesis (1)

EBV (1)

Endogenous Metabolite (3)

Fungal (11)

GABA Receptor (8)

HBV (1)

HSP (1)

Influenza Virus (1)

Interleukin Related (2)

Isotope-Labeled Compounds (5)

MDM-2/p53 (1)

Mitochondrial Metabolism (2)

Monoamine Oxidase (4)

Na+/K+ ATPase (1)

nAChR (4)

NF-κB (4)

NO Synthase (1)

P-glycoprotein (2)

Parasite (39)

Phosphatase (1)

PI3K (1)

PROTAC Linkers (1)

Proton Pump (2)

RAD51 (2)

RANKL/RANK (1)

Reactive Oxygen Species (4)

Sodium Channel (5)

TNF Receptor (2)

Tyrosinase (1)

β-catenin (2)

By Research Areas:

Cancer (25)

Cardiovascular Disease (2)

Endocrinology (4)

Infection (74)

Inflammation/Immunology (17)

Metabolic Disease (2)

Neurological Disease (16)

133

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N3990

Hardwickiic acid 1 Publications Verification (-)-Hardwikiic acid	Sodium Channel	Infection Neurological Disease
Hardwickiic acid ((-)-Hardwikiic acid) is an antinociceptive compound that blocks Tetrodotoxin-sensitive voltage-dependent sodium channels. Hardwickiic acid shows insecticidal activity .

HY-158327

Insecticidal agent 9	Parasite	Others
Insecticidal agent 9 (Compound I-17) is an insecticide with good insecticidal activity. Insecticidal agent 9 has LC₅₀ values of 93.32 mg/L and 114.79 mg/L against Plutella xylostella and Ostrinia furnacalis respectively, and exhibits a mortality rate of up to 86.1% against Spodoptera frugiperda at a concentration of 500 mg/L. Insecticidal agent 9 can act simultaneously on the ecdysone receptor (EcR) and three chitinases (OfChtI, OfChtII, and OfChi-h), demonstrating good binding activity (to EcR) and inhibitory rates (to the three chitinases). Insecticidal agent 9 can be used in research for pest management .

HY-156256

Insecticidal agent 4	Bacterial	Infection
Insecticidal agent 4 (compound IA-8) is an aryl isoxazoline derivative with insecticidal activity against M. separate .

HY-P10390

Insecticidal agent 11	Parasite	Infection
Insecticidal agent 11 (compound Q6) is a potent *insect* growth regulator (IGR)-based insecticide. Insecticidal agent 11 shows high insecticidal activity against Diploptera punctata by inhibiting juvenile hormone (JH) biosynthesis. Insecticidal agent 11 also exhibits insecticidal activity against Plutella xylostella .

HY-168570

Insecticidal agent 16	Parasite	Infection
Insecticidal agent 16 (compound A21) is a potent insecticidal agent. Insecticidal agent 16 shows insecticidal activities against Plutella xylostella and Spodoptera frugiperda with LC₅₀ values of 1.2 and 13.2 µg/mL, respectively .

HY-N8355

Beauveriolide I	Endogenous Metabolite	Infection
Beauveriolide I is the metabolite of Entomopathogenic Fungi Beauveria sp.. Beauveriolide I (1) exhibits moderate insecticidal activities against Spodoptera litura and Callosobruchus chinensis .

HY-N8668

Eudesmane K	Others	Others
Eudesmane K exhibits insecticidal activity against main pests to crops Lipaphis erysimi, Sitobion avenae, Rhopalosiphum padi, and Aphis craccivora .

HY-151470

Chitinase-IN-5	Parasite	Others
Chitinase-IN-5 (8i) is a potent chitinase OfChi-h inhibitor with an IC₅₀ value of 0.051 μM. Chitinase-IN-5 shows good insecticidal activity, it can be used for the research of green pest control and management .

HY-N3497

Isochamaejasmin	NF-κB DNA/RNA Synthesis Parasite Apoptosis	Infection Cancer
Isochamaejasmin is a biflavonoid with anti-cancer, antiplasmodial and insecticidal activities. Isochamaejasmin displays a potent NF-κB (NF-κB) activation activity. Isochamaejasmin could cause DNA damage and induce apoptosis via the mitochondrial pathway in AW1 cells . Isochamaejasmin also has a moderate antiplasmodial activity (IC₅₀ of 7.3 μM for *P. falciparum*) and relatively low cytotoxicity (CC₅₀ of 29.0 μM) .

HY-151469

Chitinase-IN-4	Parasite	Others
Chitinase-IN-4 (compound 8f), an azo-aminopyrimidine derivative, is a potent, selective OfChi-h inhibitor with an IC₅₀ value of 0.1 μM. Chitinase-IN-4 has good insecticidal activity. Chitinase-IN-4 can be used in research of green pest control and management .

HY-B0827A

(R)-Dinotefuran (R)-MTI-446	nAChR Parasite	Infection
(R)-Dinotefuran ((R)-MTI-446), a neonicotinoid pesticide, exhibits comparative insecticidal activities (1.7-2.4 times) to typical sucking pests Aphis gossypii and Apolygus lucorum compared to racemic mixtures by inhibiting nicotinic acetylcholine receptors. (R)-Dinotefuran has a good efficacy in controlling target pests while minimizing hazard to honeybees .

HY-N11706

β-Cedrene (+)-β-Cedrene	Fungal	Infection Inflammation/Immunology
β-Cedrene ((+)-β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a K_i value of 1.6 μM .

HY-142916

Insecticidal agent 1	Others	Others
Insecticidal agent 1 displays more potent insecticidal activity than obacunone and toosendanin.

HY-162497

Insecticidal agent 12	nAChR	Others
Insecticidal agent 12 (Compound F45) has insecticidal activity (LC₅₀: 2.94 μg/mL). Insecticidal agent 12 is an nAChR inhibitor .

HY-B1973

Diflubenzuron	Others	Others
Diflubenzuron, the active ingredient of the insecticide Dimilin, is a chitin-synthesis inhibiting insecticide. Diflubenzuron possesses larvicidal and ovicidal activities .

HY-122401

Daigremontianin	Others	Infection
Daigremontianin is an insecticidal bufadienolide that can be isolated from K. daigremontiana x tubiflora. Daigremontianin shows insecticidal activity for silkworm .

HY-N12130

Celangulatin D	Others	Others
Celangulatin D (Compound 2) is an insecticidal sesquiterpene polyol ester isolated from the root bark of the natural Celastrus angulatus. Celangulatin D has insecticidal activity against armyworms. Celangulatin D can be used for insecticidal and anti-tumor research .

HY-163776

Insecticidal agent 13	Others	Others
Insecticidal agent 13 (compound A15) is a phenylpyrazole derivative with insecticidal and acaricidal activities, which can be used in the research of agricultural pest control .

HY-118428

Fluenetil M2060; TH 367-1	Others	Others
Fluenetil (M2060) is a compound with insecticidal activity.

HY-B1973S

Diflubenzuron-d4	Isotope-Labeled Compounds	Others
Diflubenzuron-d₄ is the deuterium labeled Diflubenzuron[1]. Diflubenzuron, the active ingredient of the insecticide Dimilin, is a chitin-synthesis inhibiting insecticide. Diflubenzuron possesses larvicidal and ovicidal activities[2][3].

HY-149697

Insecticidal agent 6	Parasite	Others
Insecticidal agent 6 (Compound Im) is an insect ryanodine receptors (RyRs) inhibitor, with an EC₅₀ value of 0.6308 µM against S. frugiperda RyRs. Insecticidal agent 6 has excellent insecticidal activity against lepidopteran pests and can be used for research on pests and diseases .

HY-12643

Eprinomectin MK-397	Parasite Bacterial Reactive Oxygen Species β-catenin Apoptosis Autophagy	Infection Cancer
Eprinomectin (MK-397) is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity .

HY-119649

Flonicamid IKI220	Parasite	Infection
Flonicamid (IKI220) is a novel systemic *insecticide* with selective activity against hemipterous pests. The main insecticidal mechanism of flonicamid is starvation based on the inhibition of stylet penetration to plant tissues .

HY-N7939

Celangulin XIX	Others	Others
Celangulin XIX is a insecticidal that can be isolated from Celastrus angulatu. Celangulin XIX has strong insecticidal activity against Mythimna separate with an ED₅₀ of 73.3 μg/g .

HY-130423

Milbemycin A3	Others	Others
Milbemycin A3 is an insecticide with acaricidal and nematocidal activities .

HY-N1418

(S)-(-)-Tetrahydroberberine (-)-Canadine; (S)-(-)-Canadine	Others	Inflammation/Immunology
(S)-(-)-Tetrahydroberberine is an alkaloid and intermediate in the biosynthesis of berberine with insecticidal activity .

HY-B0834

(±)-Indoxacarb (RS)-Indoxacarb; DPX-JW062	Sodium Channel	Neurological Disease
Indoxacarb ((±)-Indoxacarb; DPX-JW062) is a broad-spectrum oxadiazine insecticide with high insecticidal activity and low mammalian toxicity. Indoxacarb blocks insect _{sodium channels} (Sodium Channel) in nerve preparations and isolated neurons .

HY-B1973R

Diflubenzuron (Standard)	Others	Others
Diflubenzuron (Standard) is the analytical standard of Diflubenzuron. This product is intended for research and analytical applications. Diflubenzuron, the active ingredient of the insecticide Dimilin, is a chitin-synthesis inhibiting insecticide. Diflubenzuron possesses larvicidal and ovicidal activities .

HY-N12093

Cevadine	Sodium Channel Parasite	Infection
Cevadine is a voltage-sensitive sodium channel agonist. Cevadine has *insecticidal* activity .

HY-N3156

Odoratone Dehydroodoratol	Others	Others
Odoratone (Dehydroodoratol) has insecticidal activity (LC₅₀: 154 ppm) .

HY-167826

Spiropidion	Others	Others
Spiropidion is a novel tetrameric acid pesticide with highly effective insecticidal and acaricidal activity .

HY-149864

Insecticidal agent 3	Others	Others
Insecticidal agent 3 is a multichitinase inhibitors, belongs to insect growth regulators (IGRs)，with K_is of 0.8μM, 11.9 μM, and 2.3 μM for Of ChtI, Of ChtII, and Of Chi-h, respectively. Insecticidal agent 3 exhibits insecticidal activity against two lepidopteran pests by interfering with normal insect growth and molting .

HY-12643R

Eprinomectin (Standard) MK-397 (Standard)	Parasite Bacterial Reactive Oxygen Species β-catenin Apoptosis Autophagy	Infection Cancer
Eprinomectin (Standard) is the analytical standard of Eprinomectin. This product is intended for research and analytical applications. Eprinomectin is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity .

HY-W775317

Benzpyrimoxan NNI-1501	Others	Infection
Benzpyrimoxan (NNI-1501) is an insecticide that shows remarkable activity against nymphs of rice planthoppers .

HY-12643S

Eprinomectin-d3 MK-397-d₃	Isotope-Labeled Compounds	Infection Cancer
Eprinomectin-d₃ (MK-397-d₃) is the deuterium-labeled Eprinomectin (HY-12643). Eprinomectin is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity .

HY-119649R

Flonicamid (Standard)	Parasite	Infection
Flonicamid (Standard) is the analytical standard of Flonicamid. This product is intended for research and analytical applications. Flonicamid (IKI220) is a novel systemic insecticide with selective activity against hemipterous pests. The main insecticidal mechanism of flonicamid is starvation based on the inhibition of stylet penetration to plant tissues .

HY-N3507

Euojaponine D	Others	Others
Euojaponine D is a sesquiterpene alkaloids from Euonymus japonica (Celastraceae). Celastraceae has potent insecticidal activity .

HY-153732

Insecticidal agent 2	Parasite	Infection
Insecticidal agent 2 (example 2) is a pesticide that exhibits potent growth-retarding activity against pests .

HY-N1520

Rediocide A	Others	Infection
Rediocide A is a highly modified daphnane with potent insecticidal activity. Rediocide A can be isolated from Trigonostemon reidioides .

HY-N12548

Thamnosmonin	Others	Others
Thamnosmonin is a coumarin that can be isolated from Sida acuta and Sida rhombifolia. Thamnosmonin has insecticidal activity .

HY-125040

Isariin C	Endogenous Metabolite	Inflammation/Immunology
Isariin C is a flavonoid glycoside with antioxidant activity. Isariin C activates angiogenesis. Isariin C exhibits insecticidal activity in certain insects .

HY-B0834R

(±)-Indoxacarb (Standard)	Sodium Channel	Neurological Disease
Indoxacarb (Standard) is the analytical standard of Indoxacarb. This product is intended for research and analytical applications. Indoxacarb ((±)-Indoxacarb; DPX-JW062) is a broad-spectrum oxadiazine insecticide with high insecticidal activity and low mammalian toxicity. Indoxacarb blocks insect sodium channels (Sodium Channel) in nerve preparations and isolated neurons .

HY-169169

Insecticidal agent 14	Parasite	Infection
Insecticidal agent 14 (compound 8a) shows potent insecticidal activity against Plutella xylostella and Mythimna separata, with LC₅₀ values of 0.79 and 9.17 mg/L against P. xylostella, respectively, and 3.58 and 83.09 mg/L against M. separata, respectively .

HY-12779

Cyantraniliprole HGW-86	Parasite	Others
Cyantraniliprole (HGW-86) is a potent and selective aniline receptor activator with oral activity. Cyantraniliprole has insecticidal and antioxidant activity .

HY-N1304

Shyobunone Shyobunon	Others	Others
Shyobunone (Shyobunon) is a nature product that could be isolated from Acorus calamus rhizomes. Shyobunone has insecticidal and repellant activity .

HY-N6689

Destruxin A 1 Publications Verification	Antibiotic	Infection Cancer
Destruxin A (DA) is a cyclo-peptidic mycotoxin from the entomopathogenic fungus Metarhizium anisopliae, with insecticidal, anti-viral and antiproliferative activities .

HY-W011035

Dodecamethylpentasiloxane	Parasite	Infection
Dodecamethylpentasiloxane is a component of siloxanes and can be used as silicone oil. Dodecamethylpentasiloxane exhibits insecticidal activity against bed bug .

HY-133216

Bupirimate	Fungal	Infection
Bupirimate possesses antifungal activity. Bupirimate is compatible with most of fungicides, insecticides and adjuvants, with very limited exceptions on some crops .

HY-126872

Nikkomycin I	Antibiotic Fungal	Infection
Nikkomycin I is a nucleoside peptide antibiotic found in Streptomyces tendae of the genus Streptomyces, with high antifungal, insecticidal, and acaricidal activities .

HY-N0263

Toosendanin 4 Publications Verification	Others	Inflammation/Immunology
Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities .

Cat. No.	Product Name	Type

HY-W127493

1-Hexacosanol Ceryl Alcohol	Cell Assay Reagents
1-Hexacosanol is a compound in the bioactive fraction of plant extracts that mediates insecticidal activity. 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects .

HY-W127474

Ethyl pentadecanoate	Drug Delivery
Ethyl pentadecanoate is an organic compound that is commonly used as a flavoring and food additive, and can also be used in industrial manufacturing, such as the production of lubricants and surfactants. In addition, Ethyl pentadecanoate has biological activities such as antibacterial, insecticidal and antiseptic.

HY-W127493R

1-Hexacosanol (Standard)

Cell Assay Reagents

1-Hexacosanol (Standard) is the analytical standard of 1-Hexacosanol. This product is intended for research and analytical applications. 1-Hexacosanol is a compound in the bioactive fraction of plant extracts that mediates insecticidal activity. 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects .

Cat. No.	Product Name	Target	Research Area

HY-N6689

Destruxin A 1 Publications Verification	Antibiotic	Infection Cancer
Destruxin A (DA) is a cyclo-peptidic mycotoxin from the entomopathogenic fungus Metarhizium anisopliae, with insecticidal, anti-viral and antiproliferative activities .

HY-P10390

Insecticidal agent 11	Parasite	Infection
Insecticidal agent 11 (compound Q6) is a potent *insect* growth regulator (IGR)-based insecticide. Insecticidal agent 11 shows high insecticidal activity against Diploptera punctata by inhibiting juvenile hormone (JH) biosynthesis. Insecticidal agent 11 also exhibits insecticidal activity against Plutella xylostella .

HY-125040

Isariin C	Endogenous Metabolite	Inflammation/Immunology
Isariin C is a flavonoid glycoside with antioxidant activity. Isariin C activates angiogenesis. Isariin C exhibits insecticidal activity in certain insects .

HY-P3100

Orfamide A	Parasite	Infection
Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC₅₀ value of 34.5 μg/mL .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N3990

Hardwickiic acid 1 Publications Verification (-)-Hardwikiic acid	Classification of Application Fields Neurological Disease Pueraria tuberosa (Roxb. ex Willd.) DC. Source classification Plants Compositae Infection other families Terpenoids Croton tiglium Linn. Diterpenoids Euphorbiaceae Disease Research Fields	Sodium Channel
Hardwickiic acid ((-)-Hardwikiic acid) is an antinociceptive compound that blocks Tetrodotoxin-sensitive voltage-dependent sodium channels. Hardwickiic acid shows insecticidal activity .

HY-N1418

(S)-(-)-Tetrahydroberberine (-)-Canadine; (S)-(-)-Canadine	Alkaloids Structural Classification Classification of Application Fields Source classification Corydalis ophiocarpa Hook. f. et Thoms. Plants Isoquinoline Alkaloids Inflammation/Immunology Disease Research Fields Papaveraceae	Others
(S)-(-)-Tetrahydroberberine is an alkaloid and intermediate in the biosynthesis of berberine with insecticidal activity .

HY-N8355

Beauveriolide I	Infection Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Disease Research Fields	Endogenous Metabolite
Beauveriolide I is the metabolite of Entomopathogenic Fungi Beauveria sp.. Beauveriolide I (1) exhibits moderate insecticidal activities against Spodoptera litura and Callosobruchus chinensis .

HY-N8668

Eudesmane K	Classification of Application Fields Mucuna pruriens (L.) DC. Terpenoids Sesquiterpenes Source classification Other Diseases Plants Compositae Disease Research Fields	Others
Eudesmane K exhibits insecticidal activity against main pests to crops Lipaphis erysimi, Sitobion avenae, Rhopalosiphum padi, and Aphis craccivora .

HY-N3497

Isochamaejasmin	Structural Classification Flavonoids Thymelaeaceae Stellera chamaejasme Linn. Plants Other Flavonoids	NF-κB DNA/RNA Synthesis Parasite Apoptosis
Isochamaejasmin is a biflavonoid with anti-cancer, antiplasmodial and insecticidal activities. Isochamaejasmin displays a potent NF-κB (NF-κB) activation activity. Isochamaejasmin could cause DNA damage and induce apoptosis via the mitochondrial pathway in AW1 cells . Isochamaejasmin also has a moderate antiplasmodial activity (IC₅₀ of 7.3 μM for *P. falciparum*) and relatively low cytotoxicity (CC₅₀ of 29.0 μM) .

HY-N11706

β-Cedrene (+)-β-Cedrene	Centaurea kotschyi (Boiss.) Hayek Structural Classification Natural Products Source classification Plants Compositae	Fungal
β-Cedrene ((+)-β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a K_i value of 1.6 μM .

HY-N12130

Celangulatin D	Structural Classification Terpenoids Sesquiterpenes Source classification Celastraceae Celastrus angulatus Maxim. Plants	Others
Celangulatin D (Compound 2) is an insecticidal sesquiterpene polyol ester isolated from the root bark of the natural Celastrus angulatus. Celangulatin D has insecticidal activity against armyworms. Celangulatin D can be used for insecticidal and anti-tumor research .

HY-N7939

Celangulin XIX	Structural Classification Terpenoids Sesquiterpenes Source classification Celastraceae Celastrus angulatus Maxim. Plants	Others
Celangulin XIX is a insecticidal that can be isolated from Celastrus angulatu. Celangulin XIX has strong insecticidal activity against Mythimna separate with an ED₅₀ of 73.3 μg/g .

HY-N12093

Cevadine	Structural Classification Alkaloids Other Alkaloids Source classification Veratrum oblongum Loes. Plants Melanthiaceae	Sodium Channel Parasite
Cevadine is a voltage-sensitive sodium channel agonist. Cevadine has *insecticidal* activity .

HY-N3156

Odoratone Dehydroodoratol	Triterpenes Structural Classification Terpenoids Toona sinensis (A. Juss.) Roem. Source classification Plants Meliaceae	Others
Odoratone (Dehydroodoratol) has insecticidal activity (LC₅₀: 154 ppm) .

HY-N3507

Euojaponine D	Alkaloids Classification of Application Fields Source classification Other Diseases Celastraceae Pyridine Alkaloids Plants Tripterygium wilfordii Hook. f. Disease Research Fields	Others
Euojaponine D is a sesquiterpene alkaloids from Euonymus japonica (Celastraceae). Celastraceae has potent insecticidal activity .

HY-N1520

Rediocide A	Structural Classification Terpenoids Source classification Diterpenoids Euphorbiaceae Plants	Others
Rediocide A is a highly modified daphnane with potent insecticidal activity. Rediocide A can be isolated from Trigonostemon reidioides .

HY-N12548

Thamnosmonin	Structural Classification Source classification Coumarins Camellia japonica L. Phenylpropanoids Plants Theaceae	Others
Thamnosmonin is a coumarin that can be isolated from Sida acuta and Sida rhombifolia. Thamnosmonin has insecticidal activity .

HY-N1304

Shyobunone Shyobunon	Structural Classification Araceae Terpenoids Sesquiterpenes Source classification Acorus calamus L. Plants	Others
Shyobunone (Shyobunon) is a nature product that could be isolated from Acorus calamus rhizomes. Shyobunone has insecticidal and repellant activity .

HY-N6689

Destruxin A 1 Publications Verification	Infection Structural Classification Microorganisms Classification of Application Fields Cyclopeptides Source classification Disease Research Fields Biological Pesticide Research Agricultural Research	Antibiotic
Destruxin A (DA) is a cyclo-peptidic mycotoxin from the entomopathogenic fungus Metarhizium anisopliae, with insecticidal, anti-viral and antiproliferative activities .

HY-126872

Nikkomycin I	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Fungal
Nikkomycin I is a nucleoside peptide antibiotic found in Streptomyces tendae of the genus Streptomyces, with high antifungal, insecticidal, and acaricidal activities .

HY-N0263

Toosendanin 4 Publications Verification	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Melia toosendan Sieb. et Zucc. Plants Meliaceae Inflammation/Immunology Disease Research Fields	Others
Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities .

HY-108970

Bafilomycin D	Structural Classification Natural Products Microorganisms Source classification	Proton Pump Bacterial Fungal
Bafilomycin D is a specific inhibitor of vacuolar-type ATPase (V-ATPase). Bafilomycin D has antimicrobial, insecticidal, herbicidal and cytotoxic activity .

HY-114720

Laureatin	Structural Classification Natural Products Microorganisms Source classification	Others
Laureatin is an active product that can be isolated from the marine algae Laurencia nipponica. Laureatin exhibits potent insecticidal activity against mosquitos .

HY-N4250

Periplocoside N	Infection other families Classification of Application Fields Source classification Plants Disease Research Fields Steroids	Others
Periplocoside N, a pregnane glycoside isolated from root powder of Periploca sepium, possesses insecticidal activities against the red imported fire ant .

HY-N3068

Picrasin B Nigakilactone I; Simalikalactone B	Structural Classification Natural Products Simaroubaceae Ketones, Aldehydes, Acids Source classification Plants Picrasma chinensis P. Y. Chen	Others
Picrasin B (Nigakilactone I) can be isolated from the bark of Picrasma quassioides. Picrasin B shows antifeedant and insecticidal activity against Diamondback Moth .

HY-123135

Scirpusin B	Bolboschoenus maritimus Source classification Cyperaceae Plants	Others
Scirpusin B (compound 5) is a dimeric antioxidant isolated from Scirpus maritimus L.. Scirpusin B exhibits antitumor, antifungal, insecticidal, and plant growth inhibitory activities.

HY-N7144A

Citronellyl acetate	Infection Natural Products Microorganisms Classification of Application Fields Source classification Pelargonium hortorum Plants Disease Research Fields Geraniaceae	Apoptosis
Citronellyl acetate is a monoterpene product of the secondary metabolism of plants, with antinociceptive activity. Citronellyl acetate exhibits pro-apoptotic activity in human hepatoma cells. Citronellyl acetate shows fungicidal, larvicidal, bactericidal and repelling/insecticidal effects .

HY-N9496

Piperitone	Infection Structural Classification Other Monoterpenes other families Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields	Others
Piperitone is as a powerful repellent and antiappetent agent. Piperitone is very toxic to Cymbopogon schoenanthus (C. schoenanthus) adults, newly laid eggs and to neonate larvae. Insecticidal activity .

HY-N1418A

(R)-(+)-Tetrahydroberberine (+)-Canadine; (R)-(+)-Canadine	Structural Classification Alkaloids Corydalis cava (L.) Schweigg. & Körte Microorganisms Classification of Application Fields Other Alkaloids Source classification Plants Inflammation/Immunology Disease Research Fields Papaveraceae	Others
(R)-(+)-Tetrahydroberberine is the isomer of (S)-(-)-Tetrahydroberberine (HY-N1418), and can be used as an experimental control. (S)-(-)-Tetrahydroberberine is an alkaloid and intermediate in the biosynthesis of berberine with insecticidal activity .

HY-N0238

Atractylodin 1 Publications Verification Atractydin	Infection Structural Classification Natural Products Classification of Application Fields Source classification Plants Compositae Disease Research Fields Erythrina sigmoidea Hua	Others
Atractylodin (Atractydin) is an orally active active ingredient obtained from the rhizome of Atractylodes lancea and A. chinensis. Atractylodin is a natural insecticide. Atractylodin has anti-inflammatory activity .

HY-N10743

Pipercide	Structural Classification Natural Products Source classification Piperaceae Plants Piper nigrum Linn.	Parasite
Pipercide is an amide of piper nigrum fruits. Pipercide has larvicidal activity to mosquito. Pipercide acts on the nervous system and induces repetitive discharge on the central nerve cord. Pipercide can be used as an insecticide .

HY-126744

Juncin E	Structural Classification Terpenoids Marine natural products Source classification Other marine organisms Diterpenoids	Others
Juncin E is a diterpenoid found in the soft coral Junceella juncea that exhibits significant insecticidal activity against the larvae of two important agricultural pests: southern corn rootworm and tobacco armyworm ^[2].

HY-126741

Azadirachtin 2 Publications Verification	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Other Diseases Azadirachta indica A. Juss. Plants Meliaceae Disease Research Fields Biological Pesticide Research Agricultural Research	Apoptosis Parasite NF-κB Bcl-2 Family Caspase
Azadirachtin is an oral active triterpenoid compound with anticancer, antimalarial, anti-inflammatory, and insecticidal activities. Azadirachtin induces cell apoptosis through the mitochondrial pathway (by inhibiting Bcl-2/Bax ratio or activating Apaf-1 and caspase-3) or through death receptors (by inhibiting TNFR activation). Additionally, Azadirachtin exerts its anti-inflammatory effects by inhibiting NF-кB signaling pathway activation, and it exhibits insecticidal activity by inducing apoptosis in insect cells .

HY-133721

Chamaechromone	Flavonoids Classification of Application Fields Thymelaeaceae Source classification Phenols Polyphenols Plants Biflavones Disease Research Fields Inflammation/Immunology Stellera chamaejasme L.	HBV
Chamaechromone is a biflavonoid ingredient isolated from the roots of Stellera chamaejasme L. (Thymelaeaceae). Chamaechromone possesses anti-hepatitis B virus (HBV) effects against the surface antigen of HBV (HBsAg) secretion and has insecticidal activities .

HY-N7144AR

Citronellyl acetate (Standard)	Structural Classification Natural Products Microorganisms Source classification Pelargonium hortorum Plants Geraniaceae	Apoptosis
Citronellyl acetate (Standard) is the analytical standard of Citronellyl acetate. This product is intended for research and analytical applications. Citronellyl acetate is a monoterpene product of the secondary metabolism of plants, with antinociceptive activity. Citronellyl acetate exhibits pro-apoptotic activity in human hepatoma cells. Citronellyl acetate shows fungicidal, larvicidal, bactericidal and repelling/insecticidal effects .

HY-W089538

2-Ethyl-6-methylphenol	Infection Monophenols other families Classification of Application Fields Source classification Phenols Plants Disease Research Fields	Bacterial
2-Ethyl-6-methylphenol, an alkylphenol, is isolated form the tumorigenic neutral subfraction of cigarette smoke condensate. 2-Ethyl-6-methylphenol exhibits insecticidal and bactericidal activities .

HY-N12131

Ejaponine A	Structural Classification Terpenoids Sesquiterpenes Source classification Euonymus japonicus Thunb. Celastraceae Plants	Others
Ejaponine A (Compound 1) is an insecticidal sesquiterpene ester. Ejaponine A is obtained from the natural Euonymus japonicus. Ejaponine A has Mythimna separata killing activity (LD₅₀89.2 μgg ^-1). Ejaponine A is used to kill Mythimna separata .

HY-Y0946

Acetamide	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Biochemical Assay Reagents
Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity. Acetamide derivatives may has antioxidant activity and potential anti-inflammatory activity. Acetamide holds promise for research in the fields of anti-inflammatory and cancer studies .

HY-N9496R

Piperitone (Standard)	Structural Classification Other Monoterpenes other families Terpenoids Source classification Plants	Others
Piperitone (Standard) is the analytical standard of Piperitone. This product is intended for research and analytical applications. Piperitone is as a powerful repellent and antiappetent agent. Piperitone is very toxic to Cymbopogon schoenanthus (C. schoenanthus) adults, newly laid eggs and to neonate larvae. Insecticidal activity .

HY-119604

Cafamycin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Cafamycin is a polyether antibiotic active against gram-positive bacteria, including Staphylococcus aureus. Cafamycin also demonstrates insecticidal and antiprotozoal activities. Cafamycin is isolated from the culture fluid of Streptomyces sp., an organism producing the anthracycline antibiotic galtamycin .

HY-138800

Spinosad 3 Publications Verification	Structural Classification Natural Products Microorganisms Neurological Disease Classification of Application Fields Source classification Disease Research Fields Biological Pesticide Research Agricultural Research	nAChR
Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete (Saccharopolyspora spinosa), is a biological neurotoxic insecticide with a broader action spectrum. Spinosad targets the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. Spinosad has an excellent environmental and mammalian toxicological profile. Larvicidal activity .

HY-W024365

3-tert-Butyl-4-methoxyphenol	Structural Classification Monophenols Source classification Jatropha curcas Linn. Phenols Euphorbiaceae Plants	PROTAC Linkers
3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system .

HY-Y0946R

Acetamide (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Biochemical Assay Reagents
Acetamide (Standard) is the analytical standard of Acetamide. This product is intended for research and analytical applications. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity. Acetamide derivatives may has antioxidant activity and potential anti-inflammatory activity. Acetamide holds promise for research in the fields of anti-inflammatory and cancer studies .

HY-N8472

Chrodrimanin B	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	GABA Receptor
Chrodrimanin B, a metabolite of a fungal, is a potent, non-open-channel-blocking antagonist on?B.?mori GABAR RDL with an IC₅₀?of 1.13 nM. Chrodrimanin B attenuates the peak current amplitude of the GABA response of RDL with an IC₅₀?of 1.66 nM.?Chrodrimanin B, a meroterpenoid, shows insecticidal activity .

HY-133108

Azadirachtin B	Infection Structural Classification Natural Products other families Classification of Application Fields Source classification Metabolic Disease Plants Inflammation/Immunology Disease Research Fields Biological Pesticide Research Agricultural Research	EBV Parasite Phosphatase Influenza Virus
Azadirachtin B is an limonoid isolated from seed kernels of Azadirachta indica. Azadirachtin B increases alkaline phosphatase (ALP) activity and stimulates osteoblast differentiation. Azadirachtin B is active against the Epstein-Barr virus early antigen (EBV-EA). Azadirachtin B has insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral and osteogenic properties .

HY-107577

Gedunin	Infection Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Plants Inflammation/Immunology Disease Research Fields	HSP
Gedunin is a limonoid with anti-cancer, anti-viral, anti-inflammatory and insecticidal activities. Gedunin acts as a potent Hsp90 inhibitor and induces the degradation of Hsp90-dependent client proteins. Geduni may obstructs the entry of SARS-CoV-2 virus into human host cells and can be used for COVID-19 research .

HY-138800R

Spinosad (Standard)	Structural Classification Natural Products Microorganisms Source classification	nAChR
Spinosad (Standard) is the analytical standard of Spinosad. This product is intended for research and analytical applications. Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete (Saccharopolyspora spinosa), is a biological neurotoxic insecticide with a broader action spectrum. Spinosad targets the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. Spinosad has an excellent environmental and mammalian toxicological profile. Larvicidal activity .

HY-121618

α-Thujone	Infection Other Monoterpenes Platycladus orientalis (Linn.) Franco Cupressaceae Classification of Application Fields Neurological Disease Terpenoids Source classification Plants Disease Research Fields	GABA Receptor Reactive Oxygen Species Parasite Apoptosis Autophagy
α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC₅₀ for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier .

HY-N6690

Destruxin B	Infection Structural Classification Microorganisms Classification of Application Fields Cyclopeptides Source classification Disease Research Fields	Bcl-2 Family Caspase Apoptosis
Destruxin B, isolated from entomopathogenic fungus Metarhizium anisopliae, is one of the cyclodepsipeptides with insecticidal and anticancer activities. Destruxin B induces apoptosis via a Bcl-2 Family-dependent mitochondrial pathway in human nonsmall cell lung cancer cells . Destruxin B significantly activates caspase-3 and reduces tumor cell proliferation through caspase-mediated apoptosis, not only in vitro but also in vivo .

HY-114936

Piericidin A 1 Publications Verification AR-054	Structural Classification Neurological Disease Classification of Application Fields Source classification Anti-parasitic Antibacterial Disease Research Other Antibiotics Infection Microorganisms Antibiotics Anticancer Disease Research Fields	Bacterial ADC Cytotoxin Antibiotic Mitochondrial Metabolism
Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity .

HY-N6739

Beauvericin	Cardiovascular Disease Structural Classification Human Gut Microbiota Metabolites Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Endogenous metabolite Disease Research Fields	Bacterial Apoptosis Fungal PI3K Akt TNF Receptor Interleukin Related
Beauvericin is a cyclohexapeptide Fusarium toxin with insecticidal, antibacterial, anticancer, antiviral and cytotoxic activities. Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis, thereby inhibiting the growth of HCC. In addition, Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages .

HY-N3980

Guaiol Champacol; Guaiac alcohol	Infection Structural Classification Natural Products Classification of Application Fields Source classification Distemonanthus benthamianus Baill. Plants Compositae Disease Research Fields	Autophagy RAD51
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC₅₀ of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions ^[4]

HY-W050154R

Kojic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Parasite Tyrosinase NF-κB CDK
Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields .

HY-N3980R

Guaiol (Standard)	Structural Classification Natural Products Source classification Distemonanthus benthamianus Baill. Plants Compositae	Autophagy RAD51
Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]

Cat. No.	Product Name	Chemical Structure

HY-Y0055S

Phenothiazine-d8
Phenothiazine-d₈ is the deuterium labeled Phenothiazine. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases[1][2].

HY-B1973S

Diflubenzuron-d4
Diflubenzuron-d₄ is the deuterium labeled Diflubenzuron[1]. Diflubenzuron, the active ingredient of the insecticide Dimilin, is a chitin-synthesis inhibiting insecticide. Diflubenzuron possesses larvicidal and ovicidal activities[2][3].

HY-12643S

Eprinomectin-d3
Eprinomectin-d₃ (MK-397-d₃) is the deuterium-labeled Eprinomectin (HY-12643). Eprinomectin is a type of avermectin. Eprinomectin, as a broad-spectrum fungicide, has insecticidal, insecticidal and acaricidal activities. Eprinomectin induces apoptosis and autophagy in prostate cancer cells and has antitumor activity .

HY-132409S

Monocrotophos-d6
Monocrotophos-d₆ is the deuterium labeled Monocrotophos. Monocrotophos. Monocrotophos is an organophosphate insecticide with broad application in crops. Monocrotophos inhibits the activity of the acetylcholine esterase (AChE) enzyme and affects the neurotransmission between neurons[1].

HY-B1111S1

Amitraz-d3
Amitraz-d₃ is the deuterium labeled Amitraz. Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis.

HY-B1111S

Amitraz-d6
Amitraz-d6 (BTS-27419-d6) is the deuterium labeled Amitraz. Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis.

HY-B0822S1

Fipronil-13C6

Fipronil- ¹³C₆ is the ¹³C-labeled Fipronil. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Insecticidal activity

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products