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anions

" in MedChemExpress (MCE) Product Catalog:

133

Inhibitors & Agonists

7

Fluorescent Dye

22

Biochemical Assay Reagents

5

Peptides

31

Natural
Products

5

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W042301

    Others Cardiovascular Disease
    Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE) .
    Xipamide
  • HY-130015
    HKSOX-1 (5/6-mixture)
    2 Publications Verification

    Reactive Oxygen Species Others
    HKSOX-1 is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 exhibits excellent selectivity and sensitivity towards superoxide anion radical .
    HKSOX-1 (5/6-mixture)
  • HY-N10450

    1-Ethoxycarbonyl-β-carboline

    Reactive Oxygen Species Inflammation/Immunology
    Kumujian A (1-Ethoxycarbonyl-β-carboline), an anti-inflammatory agent, inhibits both superoxide anion generation (IC50 = 4.87 μg/mL) and elastase release (IC50 = 6.29 μg/mL) .
    Kumujian A
  • HY-130017

    Reactive Oxygen Species Others
    HKSOX-1r (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1r (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical .
    HKSOX-1r (5/6-mixture)
  • HY-N9895

    Others Infection Inflammation/Immunology
    3,5-Dicaffeoyl-epi-quinic acid can be extracted from Chrysanthemum morifolium. 3,5-Dicaffeoyl-epi-quinic acid has antioxidant activities. 3,5-Dicaffeoyl-epi-quinic acid can scavenge DPPH radical and superoxide anion radical, with IC50s of 5.6 and 2.9 μg/mL respectively .
    3,5-Dicaffeoyl-epi-quinic acid
  • HY-112939

    MCI-196; Colestimide

    Others Metabolic Disease
    Colestilan (MCI-196) is a non-absorbed, non-calcium-based phosphate binder and is also a non-metallic, anion exchange resin. Colestilan is orally active and can be used for hypercholesterolaemia research .
    Colestilan
  • HY-121137

    BocMPO

    Others Others
    BMPO (BocMPO) is a cell-permeable superior spin trap with favorable chemical and spectroscopic features. BMPO (BocMPO) can be used for detecting thiyl radicals, hydroxyl radicals, superoxide anions and glutathiyl radicals .
    BMPO
  • HY-N11895

    Reactive Oxygen Species Inflammation/Immunology
    Isorabaichromone is a potent antioxidant agent. Isorabaichromone shows a potent antioxidative activity and exhibits DPPH radical and superoxide anion scavenging activities .
    Isorabaichromone
  • HY-126603

    Others Infection
    Asperlactone has anti-inflammatory activity. Asperlactone inhibits superoxide anion generation. Asperlactone is a fungal metabolite that can be isolated from isolated from Aspergillus ochraceus .
    Asperlactone
  • HY-W042301R

    Others Cardiovascular Disease
    Xipamide (Standard) is the analytical standard of Xipamide. This product is intended for research and analytical applications. Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE) .
    Xipamide (Standard)
  • HY-149422

    Fluorescent Dye Neurological Disease
    NIR-FP is a near-infrared fluorescent probe with high sensitivity and selectivity for superoxide anion O 2-. O 2- is the main precursor of ROS, and ferroptosis-mediated epilepsy models can be dynamically tracked by detecting O 2-. Ferroptosis-mediated epilepsy models include: kainic acid (HY-N2309)-induced chronic epilepsy model, Pentylenetetrazole-induced acute epilepsy model, and pilocarpine (HY-B0726A)-induced epilepsy model .
    NIR-FP
  • HY-N9095

    Others Neurological Disease
    Curculigoside C is a phenolic glucoside with potent antioxidative and neuroprotective activities. Curculigoside C shows IC50 values of 0.25 mM and 0.88 mM for hydroxyl radicals and superoxide anion radicals, respectively .
    Curculigoside C
  • HY-125792

    Reactive Oxygen Species Ras Inflammation/Immunology
    Nexinhib20 is a specific Rab27a-JFC1 interaction inhibitor with a calculated IC50 of 2.6 μM. Nexinhib20 significantly inhibits superoxide anion production. Nexinhib20 efficiently decreases exocytosis of azurophilic granules in neutrophils stimulated with fMLP, GM-CSF or both. Nexinhib20 has a significant anti-inflammatory activity .
    Nexinhib20
  • HY-121693

    MDL101114ZA free base

    VDAC RAD51 Cancer
    DIDS is a dual inhibitor of ABCA1 and VDAC1. DIDS also inhibits RAD51, inhibiting RAD51-mediated homologous pairing and strand exchange reactions. DIDS inhibits anion exchange and binding to red blood cell membranes, inhibits the activation of caspase-3 and -9, and can be used in cancer research .
    DIDS
  • HY-154912

    Others Inflammation/Immunology
    PAT1inh-B01 is a selective SLC26A6 inhibitor. PAT1inh-B01 inhibits PAT1 (a Cl -/HCO3 - exchanger)-mediated anion exchange (IC50: 350 nM). PAT1inh-B01 blocks fluid absorption in small intestine. PAT1inh-B01 can be used for research of small intestinal hyposecretory disorders .
    PAT1inh-B01
  • HY-D0086
    DIDS sodium salt
    10+ Cited Publications

    MDL101114ZA

    VDAC RAD51 Cancer
    DIDS sodium salt (MDL101114ZA) is a dual inhibitor of ABCA1 and VDAC1. DIDS also inhibits RAD51, inhibiting RAD51-mediated homologous pairing and strand exchange reactions. DIDS inhibits anion exchange and binding to red blood cell membranes, inhibits the activation of caspase-3 and -9, and can be used in cancer research .
    DIDS sodium salt
  • HY-154912A

    Others Inflammation/Immunology
    PAT1inh-B01 hydrocholide is a selective SLC26A6 inhibitor. PAT1inh-B01 hydrocholide inhibits PAT1 (a Cl -/HCO3 - exchanger)-mediated anion exchange (IC50: 350 nM). PAT1inh-B01 hydrocholide blocks fluid absorption in small intestine. PAT1inh-B01 hydrocholide can be used for research of small intestinal hyposecretory disorders .
    PAT1inh-B01 hydrochloride
  • HY-122009

    Indoxyl-β-D-glucoside

    Fluorescent Dye OAT Others
    Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4 .
    Indican
  • HY-157238

    Others Others
    AEX anion-exchange resin 2 is a AEX commonly used filler and is a strong anion exchange medium, Particle size: ~90μm. AEX anion-exchange resin 2 can be used in Ion exchange chromatography
    AEX Anion-exchange resin 2
  • HY-157239

    Others Cancer
    AEX HQ Anion-exchange resin (POROS 50HQ) is AEX commonly used filler. AEX HQ Anion-exchange resin is HQ strong anion exchange resin and can purify targeting protein .
    AEX HQ Anion-exchange resin
  • HY-W115727B

    PAM,Anion,Mw 18 million

    Biochemical Assay Reagents Others
    Polyacrylamide,Anion,Mw 18 million (PAM,Anion,Mw 18 million) can be used to synthesize water-soluble polymers. Polyacrylamide,Anion,Mw 18 million is a biomaterial or organic compound that can be used as a biomaterial or organic compound related to life science research .
    Polyacrylamide,Anion,Mw 18 million
  • HY-D0876

    Biochemical Assay Reagents Others
    POPSO is a zwitterionic buffer, increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC50 value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5 .
    POPSO
  • HY-157236

    Others Others
    AEX Anion-exchange resin 1 is a strong anion exchange chromatography resin, based on monodisperse polystyrene/divinylbenzene (PS-DVB), with a particle size of 50 μm and an ionic ligand of –CH2N + (CH3)3. AEX Anion-exchange resin 1 can be used for the separation and purification of biological macromolecules such as proteins, antibodies, and viral vaccines.
    AEX Anion-exchange resin 1
  • HY-W115727A

    PAM,Anion,Mw 14-16 million

    Biochemical Assay Reagents Others
    Polyacrylamide,Anion,Mw 14-16 million (PAM,Anion,Mw 14-16 million) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    Polyacrylamide,Anion,Mw 14-16 million
  • HY-W115727

    PAM,Anion,Mw 10-12 million

    Biochemical Assay Reagents Others
    Polyacrylamide,Anion,Mw 10-12 million (PAM,Anion,Mw 10-12 million) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    Polyacrylamide,Anion,Mw 10-12 million
  • HY-148682

    Glycyrrhetic acid 3-O-hydrogen sulfate

    OAT 11β-HSD Drug Metabolite Metabolic Disease Inflammation/Immunology
    18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)) is a potent type 2 11β-hydroxysteroid dehydrogenase (11β-HSD2) inhibitor with an IC50 of 0.10 µM using rat kidney microsome. 18β-Glycyrrhetyl-3-O-sulfate is the major metabolite of Glycyrrhetinic acid (GA). 18β-Glycyrrhetyl-3-O-sulfate is the substrate of organic anion transporter (OAT) 1 and OAT3. 18β-Glycyrrhetyl-3-O-sulfate has anti-inflammatory effects and has the potential for pseudohyperaldosteronism research .
    18β-Glycyrrhetyl-3-O-sulfate
  • HY-103703

    Others Others
    DEAE Cross-linked dextran A 25 is a weak anion exchanger .
    DEAE Cross-linked dextran A 25
  • HY-142655

    Farnesyl Transferase Infection
    Ftase inhibitor III is an anion-dependent Farnesyltransferase inhibitor from a phenotypic screen.
    Ftase inhibitor III
  • HY-137148

    Others Cancer
    DIOA is a potent acid-sensitive outwardly rectifying (ASOR) anion channel antagonist .
    DIOA
  • HY-N8217

    Others Inflammation/Immunology
    4-O-Cinnamoylquinic acid could inhibit superoxide anion generation in human neutrophils .
    4-O-Cinnamoylquinic acid
  • HY-107959

    Others
    Colestipol hydrochloride, a hypocholesterolemic bile acid‐binding anion‐exchange polymer, is used in the study of hypercholesterolaemia .
    Colestipol hydrochloride
  • HY-W155121

    N,N-Bis(3-D-gluconamidopropyl)cholamide

    Biochemical Assay Reagents Others
    Big CHAP are aqueous micelles of anionic cholate analogues .
    Big CHAP
  • HY-U00005

    Reactive Oxygen Species Inflammation/Immunology
    AD 0261 is a radical scavenger which displays strong inhibitory action on the generation of lipid peroxides and superoxide anions.
    AD 0261
  • HY-N2183

    Quercetin 3-O-sophoroside

    Others Others
    Baimaside (Quercetin 3-O-sophoroside) is isolated from the flowers of A. venetum, is a scavenger of superoxide anions .
    Baimaside
  • HY-141490

    Others Others
    Beta-D-Glucopyranosyl nitromethane, as a salt of a strongly basic anion exchanger in the OH cycle, is a glycosyl derivative of nitromethane .
    Beta-D-Glucopyranosyl nitromethane
  • HY-Y0569H

    Biochemical Assay Reagents Others
    Magnesium D-gluconate hydrate, 98% is a strong chelating agent that chelates calcium, iron, aluminum, copper, and other heavy metal anions.
    Magnesium D-gluconate hydrate, 98%
  • HY-100244

    Chloride Channel Neurological Disease
    NS1652 is a reversible anion conductance inhibitor, blocks chloride channel, with an IC50 of 1.6 μM in human and mouse red blood cells.
    NS1652
  • HY-W127701

    1-Butyl-1-methylpiperidinium bis(trifluoromethylsulfonyl)imide

    Biochemical Assay Reagents Others
    [Bmpip][NTf2] is composed of 1-butyl-1-methylimidazolium cation and bis(trifluoromethylsulfonyl)imide anion.
    [Bmpip][NTf2]
  • HY-156468

    Others Inflammation/Immunology
    Antioxidant agent-17 (compound 59) is a potent inhibitor of superoxide anion generation activity, with an IC50 of 9.06 nM .
    Antioxidant agent-17
  • HY-N1579
    Pyrogallol
    3 Publications Verification

    Endogenous Metabolite Fungal Apoptosis Infection
    Pyrogallol is a polyphenol compound, which has anti-fungal and anti-psoriatic properties. Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions.
    Pyrogallol
  • HY-D0217
    Sulfobromophthalein disodium salt
    3 Publications Verification

    Bromosulfophthalein disodium salt

    Fluorescent Dye Metabolic Disease
    Sulfobromophthalein (Bromosulfophthalein) disodium salt is an organic anion dye used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of agents and metabolites .
    Sulfobromophthalein disodium salt
  • HY-109987

    Parasite Infection
    ISPA-28 is a specific plasmodial surface anion channel (PSAC) antagonist. ISPA-28 binds directly and reversibly to CLAG3 .
    ISPA-28
  • HY-N11564

    Elastase Inflammation/Immunology
    Aristololactam IIIa exhibits significant inhibitory effects on superoxide anion generation and elastase release with IC50 values of 0.12 and 0.20 μg/mL, respectively .
    Aristololactam IIIa
  • HY-N8447

    Others Others
    3'-O-Methylmurraol is a coumarinthat can be found in Cnidium monnieri. 3'-O-Methylmurraol inhibits superoxide radical anion generation and elastase release .
    3'-O-Methylmurraol
  • HY-N9447
    Norbergenin
    1 Publications Verification

    Reactive Oxygen Species Neurological Disease
    Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC50 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging) .
    Norbergenin
  • HY-161502

    Fluorescent Dye Others
    DHX-SP is a fluorescent probe, which visualizes superoxide anion (O2 ·–) and peroxynitrite (ONOO ) during ferroptosis of PC12 cells and in the Parkinson’s disease model .
    DHX-SP
  • HY-N12914

    (+)-Tanzawaic acid B; GS-1302-1; 10-Deoxytanzawaic acid E

    Reactive Oxygen Species Others
    Tanzawaic acid B ((+)-Tanzawaic acid B; GS-1302-1; 10-Deoxytanzawaic acid E) is a superoxide anion production inhibitor and can be isolated from Penicillium citrinum .
    Tanzawaic acid B
  • HY-100322

    Chloride Channel Cardiovascular Disease
    H100 is a Cl - transport inhibitor, with partial effects against both the NaK2Cl cotransporter and the Band 3 anion exchanger, but no effect against KCl cotransporter, in human erythrocytes.
    H100
  • HY-149276
    SLC26A3-IN-2
    1 Publications Verification

    GLUT Metabolic Disease
    SLC26A3-IN-2 is an orally active inhibitor of anion exchanger protein SLC26A3 (IC50=360 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea .
    SLC26A3-IN-2
  • HY-149802

    GLUT Metabolic Disease
    SLC26A3-IN-1 is an inhibitor of anion exchanger protein SLC26A3 (IC50=340 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea .
    SLC26A3-IN-1

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