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Results for "

enzyme–substrate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (1) Akt (1) Antibiotic (1) Apoptosis (1) Autophagy (1) Bcl-2 Family (1) Biochemical Assay Reagents (133) Carboxypeptidase (1) Caspase (2) Cathepsin (1) COX (1) EGFR (1) Endogenous Metabolite (17) Fatty Acid Synthase (FASN) (2) Fluorescent Dye (2) Glucosylceramide Synthase (GCS) (3) Glycosyltransferase (1) HIV (1) HSV (1) Interleukin Related (1) MMP (1) mTOR (1) NF-κB (1) NO Synthase (1) Notch (1) PARP (1) Phosphatase (2) Phospholipase (1) Reactive Oxygen Species (3) Ser/Thr Protease (1) TNF Receptor (1)
By Research Areas:	Cancer (24) Cardiovascular Disease (1) Endocrinology (8) Infection (6) Inflammation/Immunology (2) Metabolic Disease (17) Neurological Disease (5)

By Targets:

Adenosine Receptor (1)

Akt (1)

Antibiotic (1)

Apoptosis (1)

Autophagy (1)

Bcl-2 Family (1)

Biochemical Assay Reagents (133)

Carboxypeptidase (1)

Caspase (2)

Cathepsin (1)

COX (1)

EGFR (1)

Endogenous Metabolite (17)

Fatty Acid Synthase (FASN) (2)

Fluorescent Dye (2)

Glucosylceramide Synthase (GCS) (3)

Glycosyltransferase (1)

HIV (1)

HSV (1)

Interleukin Related (1)

MMP (1)

mTOR (1)

NF-κB (1)

NO Synthase (1)

Notch (1)

PARP (1)

Phosphatase (2)

Phospholipase (1)

Reactive Oxygen Species (3)

Ser/Thr Protease (1)

TNF Receptor (1)

By Research Areas:

Cancer (24)

Cardiovascular Disease (1)

Endocrinology (8)

Infection (6)

Inflammation/Immunology (2)

Metabolic Disease (17)

Neurological Disease (5)

172

Inhibitors & Agonists

Fluorescent Dye

212

Biochemical Assay Reagents

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-48999A

FSK hydrochloride	Others	Cancer
FSK hydrochloride is fluorosulfonyloxybenzoyl-l-lysine, with a long and flexible aryl fluorosulfate-containing side chain that can reach protein sites that are difficult to reach by covalent linkage. FSK hydrochloride is a modified nanomolecule that targets the epidermal growth factor receptor (EGFR), creating a covalent binding that results in irreversible binding. FSK hydrochloride captures unknown enzyme-substrate interactions in living cells through genetically encoded chemical cross-linking, targeting residues beyond Cys, and cross-linking at the binding periphery. FSK hydrochloride enables the construction of bioreactive SuFEx systems for creating covalent bonds in different proteins in vitro and in vivo .

HY-W047324

4-Aminophenyl-α-D-mannopyranoside, 98% 4-Aminophenylmannoside, 98%	Biochemical Assay Reagents	Others
4-Aminophenyl-α-D-mannopyranoside, 98% is a synthetic glycoside primarily used as a molecular tool in biochemical research for studying glycosylation processes and enzyme-substrate interactions.

HY-W017353

Pseudopelletierine	Biochemical Assay Reagents	Others
Pseudopelletierine is an alkaloid compound that can be used as a enzyme substrate .

HY-116022B

4-Nitrophenyl phosphate ditromethamine p-Nitrophenyl phosphate ditromethamine	Biochemical Assay Reagents	Others
4-Nitrophenyl phosphate ditromethamine is an enzyme substrate commonly used in biochemical assays to measure the activity of various phosphatases, including alkaline phosphatase. 4-Nitrophenylphosphate has unique chemical properties that allow it to be hydrolyzed by phosphatases, releasing a yellow product that can be detected spectrophotometrically.

HY-130767

Naphthol AS-TR phosphate	Biochemical Assay Reagents	Others
Naphthol AS-TR Phosphate is a water-soluble dye commonly used as an enzyme substrate in various biochemical assays to detect alkaline phosphatase activity. Naphthol AS-TR Phosphate has unique chemical properties that allow it to be hydrolyzed by alkaline phosphatase to form a colored product that can be detected spectrophotometrically. This makes it a useful tool for monitoring enzyme activity in biological samples such as serum or urine.

HY-126877

3-Deaza-2'-deoxyadenosine	HSV	Infection
3-Deaza-2 '-deoxyadenosine is a nucleoside analog synthesized from 2' -deoxyadenosine. 3-Deaza-2 '-deoxyadenosine inhibits RNA synthesis by binding to ribose fragments of ribonucleotides, thereby preventing the formation of enzyme-substrate complexes, thereby preventing chain elongation, It can also inhibit DNA synthesis by binding deoxyribose fragments of DNA and preventing DNA polymerase from adding nucleotides to the growth chain. 3-Deaza-2 '-deoxyadenosine has antiviral activity .

HY-134459

4-Nitrophenyl Laurate	Others	Others
4-Nitrophenyl Laurate is a class of 4-nitrophenyl ester, which can be used as enzyme substrate .

HY-D1534

H-L-Ile-Amc TFA	Biochemical Assay Reagents	Others
H-L-Ile-Amc (TFA) is an enzyme substrate, and can detect the yeasts and molds in the sample using aminopeptidase substrates .

HY-W283889

Blue caprate	Biochemical Assay Reagents	Others
Blue caprate is a chromogenic enzyme substrate typically used to detect lipase activity. It is hydrolyzed by lipase to produce a blue-purple product (biosynth: EB04034).

HY-137613

Sp-TTPαS	HIV	Infection Inflammation/Immunology
Sp-TTPαS is a competitivesterile alpha motif and HD domain containing protein 1 (SAMHD1) catalysis inhibitor. Sp-TTPαS competitively inhibits TTP hydrolysis with a K_i value of 46 µM .

HY-W288676

6-Fluoro-3-indolyl-β-D-galactopyranoside	Biochemical Assay Reagents	Others
6-Fluoro-3-indolyl-β-D-galactopyranoside is a chromogenic enzyme substrate commonly used in microbiology to detect the expression of β-galactosidase in bacterial colonies.

HY-W550907

5-Bromo-4-chloro-3-indolyl-α-D-maltotrioside	Biochemical Assay Reagents	Others
5-Bromo-4-chloro-3-indolyl-α-D-maltotrioside is an enzyme substrate with chemiluminescent properties. It is used in diagnostic assays to detect bacterial and fungal infections and other diseases.

HY-P3363

Z-DEVD-AMC	Caspase	Cancer
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .

HY-W101382

5-Bromo-6-chloro-3-indolyl-N-acetyl-β-D-glucosaminide, 98%	Biochemical Assay Reagents	Others
5-Bromo-6-chloro-3-indolyl-N-acetyl-β-D-glucosaminide, 98% is a chromogenic substrate used to measure β-galactosidase activity in food, enzyme substrates, and culture media.

HY-W104635

6-Bromo-2-naphthyl-β-D-galactopyranoside 6-Bromo-2-naphthyl-beta-D-galactopyranoside	Biochemical Assay Reagents	Others
6-Bromo-2-naphthyl-β-D-galactopyranoside is a chromogenic substrate commonly used to measure β-galactosidase enzyme activity in food, enzyme substrates, and culture media. Upon hydrolysis by β-galactosidase, it generates a yellow precipitate indicating the enzyme's presence.

HY-18743

Coelenterazine 3 Publications Verification	Reactive Oxygen Species	Cancer
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate coelenterazine has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in chemiluminescent detection of peroxynitrite .

HY-D0146

Resorufin benzyl ether BzRes; 7-Benzyloxyresorufin; 7-Benzyloxyphenoxazone	Fluorescent Dye	Others
Resorufin benzyl ether (BzRes), a fluorogenic enzyme substrate, can be used to detect CYP3A4 enzyme activity. Resorufin benzyl ether modified with a recognizing moiety boronate, can be used for ONOO ^- detection via a self-immolation mechanism. Ex/Em=530-570 nm/590 nm .

HY-109051A

Arfolitixorin calcium	Endogenous Metabolite Others	Others
Arfolitixorin calcium is a bioactive compound that acts as an enzyme substrate. Arfolitixorin calcium is used as a substrate for methylenetetrahydrofolate reductase to generate 5-methyltetrahydrofolate. Arfolitixorin calcium may have potential applications in neurobiological research, particularly in studies related to gene expression and metabolism. Research on arfolitixorin calcium helps reveal the functional genetics of bird genes .

HY-B1746

Pyridoxamine 5′-phosphate	Endogenous Metabolite	Neurological Disease
Pyridoxamine 5′-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5′-phosphate is the aminated form of pyridoxal 5'-phosphate hydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5′-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate .

HY-147112

MNP-GAL	Biochemical Assay Reagents	Others
MNP-GAL is MNPs coated with galactose. MNP-Gal can be used as substrate for the assay of NAG and beta-d-galactosidase .

HY-W011704

Phosphoenolpyruvic acid cyclohexylammonium salt	Endogenous Metabolite	Others
Phosphoenolpyruvic acid cyclohexylammonium salt is the cyclohexylammonium salt form of phosphoenolpyruvic acid. Phosphoenolpyruvic acid cyclohexylammonium salt is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid cyclohexylammonium salt also exhibits cytoprotective and anti-oxidative properties .

HY-W013865

2-Nitrophenyl b-D-xylopyranoside	Biochemical Assay Reagents	Others
2-Nitrophenyl β-D-xylopyranoside is a synthetic sugar derivative that can be used to study the interaction mechanisms between enzymes, proteins, and carbohydrates. 2-Nitrophenyl b-D-xylopyranoside is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W040116

MUF-diNAG 4-Methylumbelliferyl N,N-diacetyl-β-D-chitobioside	Biochemical Assay Reagents	Others
MUF-diNAG (4-Methylumbelliferyl N,N-diacetyl-β-D-chitobioside) can be used as a fluorescent substrate. MUF-diNAG is a kind of biological materials or organic compounds that are widely used in life science research .

HY-131475

Naphthol AS-BI phosphate	Biochemical Assay Reagents	Others
Naphthol AS-BI phosphate is a substrate for acid and alkaline phosphatase and can be used in fluorescence assays. Naphthol AS-BI phosphate is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W010365

Rhodanine	Biochemical Assay Reagents	Others
Rhodanine, which can be used for anticonvulsant, antibacterial, antiviral, and antidiabetic activities, is used to determine tanninase in tannic acid-degrading fungal cultures. Rhodanine is a biomaterial or organic compound that can be used as a research-related biomaterial or organic compound in life sciences .

HY-15906

AMPPD Lumi-Phos Plus; Lumigen PPD; PPD	Phosphatase	Others
AMPPD, a 1,2-dioxo-cyclohexane derivative, is a biochemistry ultrasensitive alkaline phosphatase substrate.

HY-15911

CNP-AFU 2-Chloro-4-nitrophenyl α-L-fucopyranoside	Biochemical Assay Reagents	Others
CNP-AFU (2-Chloro-4-nitrophenyl α-L-fucopyranoside) is a substrate for alpha-L-fucosidase(AFU).

HY-15926

ONPG 4 Publications Verification 2-Nitrophenyl β-D-galactopyranoside	Biochemical Assay Reagents	Others
ONPG is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity.

HY-15927

4-Nitrophenyl β-D-glucopyranoside 1 Publications Verification	Biochemical Assay Reagents	Others
4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside can be used to measure of β-glucosidase activity .

HY-15936

γ-GT	Biochemical Assay Reagents	Others
γ-GT(63699-78-5) is a substrate for γ-glutamyl transferase in biochemical test.

HY-D0714

Tetrazolium Red 3 Publications Verification 2,3,5-Triphenyltetrazolium chloride; TPTZ; TTC	Biochemical Assay Reagents	Cardiovascular Disease
Tetrazolium Red (2,3,5-Triphenyltetrazolium chloride; TTC) is a not brain-penetrant, colorless, water-soluble dye that is reduced by mitochondrial enzymes to a deep red, water-insoluble compound (formazan) mainly in the mitochondria of living cells. Tetrazolium Red is used to observe the activity of dehydrogenase, and it turns colorless to red when exposed to hydrogen. Tetrazolium Red distinguishes between surviving and infarcted brain tissue after stroke. Tetrazolium Red has been used to stain heart tissue to measure the extent of acute lesions and also used to stain brain tissue to detect the size of the infarcted area. The absorption wavelength of Tetrazolium Red is 570 nm .

HY-D0183

ATP-polyamine-biotin 1 Publications Verification	Biochemical Assay Reagents	Others
ATP-polyamine-biotin, the first cell-permeable ATP analogue, is an efficient kinase cosubstrate. ATP-polyamine-biotin promotes biotin labeling of kinase substrates in live cells .

HY-W039911

4-Nitrophenyl α-D-galactopyranoside PNP-alpha-D-Gal; PNP-α-D-Gal	Biochemical Assay Reagents	Others
4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates .

HY-116022A

4-Nitrophenyl phosphate disodium hexahydrate 3 Publications Verification p-Nitrophenyl phosphate disodium hexahydrate	Biochemical Assay Reagents	Others
4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm .

HY-128851A

Coenzyme A trilithium	Endogenous Metabolite Fatty Acid Synthase (FASN)	Metabolic Disease
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-W016412

Coenzyme Q0 2 Publications Verification CoQ0	Apoptosis Autophagy EGFR Akt mTOR Caspase Bcl-2 Family Reactive Oxygen Species PARP COX NO Synthase TNF Receptor Interleukin Related MMP NF-κB	Neurological Disease Inflammation/Immunology Cancer
Coenzyme Q0 (CoQ0) is a potent, oral active ubiquinone compound can be derived from Antrodia cinnamomea. Coenzyme Q0 induces apoptosis and autophagy, suppresses of HER-2/AKT/mTOR signaling to potentiate the apoptosis and autophagy mechanisms. Coenzyme Q0 regulates NFκB/AP-1 activation and enhances Nrf2 stabilization in attenuation of inflammation and redox imbalance. Coenzyme Q0 has anti-angiogenic activity through downregulation of MMP-9/NF-κB and upregulation of HO-1 signaling .

HY-134421

2-Butenoyl coenzyme A lithium	Biochemical Assay Reagents	Others
2-Butenoyl coenzyme A (lithium), an active compound, can be used as a substrate for plasmodium falciparum enyl-ACP reductases and other enyl-CoA reductases. 2-Butenoyl coenzyme A lithium can be used as a substrate analogue to study the kinetics of β-hydroxyacyl-acyl-carrier protein (ACP) dehydratase (FabZ) .

HY-134423

Stearoyl coenzyme A lithium Stearoyl-CoA lithium	Biochemical Assay Reagents	Others
Stearoyl coenzyme A (Stearoyl-CoA) lithium is an active compound that can be used as a substrate for the determination of stearoyl-Coenzyme desaturase in microsomes .

HY-114294A

DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate HMG-CoA disodium hydrate	Biochemical Assay Reagents	Metabolic Disease
DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium hydrate is a disodium salt compound of HMG-CoA, is a intermediate of terpenes and ketone bodies. DL-3-Hydroxy-3-methylglutaryl coenzyme A disodium also involves in ester metabolism in vivo, as a precursor for cholesterol synthesis, and regulates cholesterol synthesis by coupling LDL receptor .

HY-134136A

Octanoyl coenzyme A lithium	Biochemical Assay Reagents	Cancer
Octanoyl coenzyme A lithium is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A lithium can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

HY-141474

Glutaryl coenzyme A lithium	Biochemical Assay Reagents	Others
Glutaryl coenzyme A lithium is a Glutaryl coenzyme A derivative. Glutaryl coenzyme A is an important endogenous metabolites. Glutaryl coenzyme A lithium can be used in HMG-CoA or Glutaryl-CoA related experiment.

HY-128851B

Coenzyme A sodium	Endogenous Metabolite Fatty Acid Synthase (FASN)	Metabolic Disease
Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-134424

Propionyl coenzyme A lithium	Endogenous Metabolite	Metabolic Disease
Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms .

HY-134425

β-Methylcrotonyl coenzyme A lithium	Endogenous Metabolite	Metabolic Disease
β-Methylcrotonyl coenzyme A lithium is an intermediate in leucine metabolism and can be used as a substrate to study the specificity and kinetics of β-methylcrotonyl coenzyme A carboxylase (MCCase) .

HY-134426

DL-β-Hydroxybutyryl coenzyme A lithium	Endogenous Metabolite	Metabolic Disease
DL-β-Hydroxybutyryl coenzyme A lithium is an intermediate in the fermentation of butyric acid and the metabolism of lysine and tryptophan, and is produced from β-hydroxybutyric acid by short-chain-CoA synthase .

HY-134428

Arachidonoyl coenzyme A lithium	Endogenous Metabolite	Metabolic Disease
Arachidonoyl coenzyme A lithium is an unsaturated fatty acyl coenzyme A, formed by the condensation of the thiol group of coenzyme A with the carboxyl group of arachidonic acid .

HY-134438

Hexanoyl coenzyme A trilithium	Endogenous Metabolite	Metabolic Disease
Hexanoyl coenzyme A trilithium is a hexanoyl-based medium-chain fatty acyl coenzyme A that is present in all organisms. Hexanoyl coenzyme A trilithium can be used as a precursor for cannabinoid biosynthesis and acts as a competitive inhibitor of medium-chain acyl coenzyme A dehydrogenase (MCAD) .

HY-B0445A

NAD sodium Maximum Cited Publications 24 Publications Verification β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine Dinucleotide sodium	Endogenous Metabolite	Metabolic Disease
NAD (β-Nicotinamide Adenine Dinucleotide) sodium is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP .

HY-126388

Trypsin Inhibitor, soybean	Ser/Thr Protease	Others
Trypsin Inhibitor, soybean is a potent and reversible inhibitor of trypsin .

HY-153101

Gal-G2-CNP	Biochemical Assay Reagents	Others
Gal-G2-CNP, a galactopyranosylmaltoside, can be used as substrate for the determination of novel amylase and pancreatic amylase .

Cat. No.	Product Name	Type

HY-P3363

Z-DEVD-AMC	Chromogenic Substrates
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .

HY-18743

Coelenterazine

3 Publications Verification

Fluorescent Dyes/Probes

Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate coelenterazine has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in chemiluminescent detection of peroxynitrite .

HY-D0719

Fluorescein Diacetate 4 Publications Verification 3,6-Diacetoxyfluoran; Di-O-acetylfluorescein	Dyes Enzyme Substrates
Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.

HY-D0146

Resorufin benzyl ether BzRes; 7-Benzyloxyresorufin; 7-Benzyloxyphenoxazone	Dyes
Resorufin benzyl ether (BzRes), a fluorogenic enzyme substrate, can be used to detect CYP3A4 enzyme activity. Resorufin benzyl ether modified with a recognizing moiety boronate, can be used for ONOO ^- detection via a self-immolation mechanism. Ex/Em=530-570 nm/590 nm .

HY-D0719R

Fluorescein Diacetate (Standard)	Dyes Enzyme Substrates
Fluorescein Diacetate (Standard) is the analytical standard of Fluorescein Diacetate. This product is intended for research and analytical applications. Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.

HY-15560A

Hoechst 34580 trihydrochloride	DNA Stain Enzyme Substrates
Hoechst 34580 (trihydrochloride) is a biochemical assay reagent.

Cat. No.	Product Name	Target	Research Area

HY-P3363

Z-DEVD-AMC	Caspase	Cancer
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .

HY-114150

D-Val-Leu-Arg-pNA	Peptides	Others
D-Val-Leu-Arg-pNA is a glandular kininoreleasing enzyme substrate that also acts as a substrate for tissue-type plasminogen activator (t-PA) with no apparent affinity for fibrin .

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enzyme–substrate

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

NaturalProducts

Natural
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