2. Gene
  3. Cat - catalase Gene

Cat - catalase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as CS1; Cas1; Catl; Cs-1; Cat01

Gene ID: 24248 | Gene type: protein coding

About Cat

Summary

Enables catalase activity. Involved in several processes, including hydrogen peroxide catabolic process; response to ozone; and response to vitamin. Located in several cellular components, including Golgi apparatus; mitochondrial intermembrane space; and peroxisome. Used to study Bacterial pneumonia; brain ischemia; cholestasis; colitis; and lung disease. Biomarker of several diseases, including artery disease (multiple); auditory system disease (multiple); end stage renal disease; eye disease (multiple); and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including acatalasia; eye disease (multiple); lung disease (multiple); osteonecrosis; and pseudoxanthoma elasticum. Orthologous to human CAT (catalase). [provided by Alliance of Genome Resources, Apr 2022]

Cat Products(1)

mRNA Protein Name
NM_012520.2 NP_036652.1 catalase
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables catalase activity IDA
IDA: Inferred from direct assay
3455767 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to growth factor stimulus IEP
IEP: Inferred from expression pattern
21276205 RGD
involved in hydrogen peroxide catabolic process IDA
IDA: Inferred from direct assay
17576767 RGD
involved in hydrogen peroxide catabolic process IMP
IMP: Inferred from mutant phenotype
14713308 RGD
involved in kidney development IMP
IMP: Inferred from mutant phenotype
22733796 RGD
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
10569634 RGD
involved in response to L-ascorbic acid IEP
IEP: Inferred from expression pattern
20698742 RGD
involved in response to UV IEP
IEP: Inferred from expression pattern
12592055 RGD
involved in response to activity IEP
IEP: Inferred from expression pattern
9250541 RGD
involved in response to amitrole IEP
IEP: Inferred from expression pattern
7195942 RGD
involved in response to cadmium ion IEP
IEP: Inferred from expression pattern
18655190 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
25038876 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
9250541 RGD
involved in response to fatty acid IEP
IEP: Inferred from expression pattern
23232760 RGD
involved in response to hyperoxia IEP
IEP: Inferred from expression pattern
19895324 RGD
involved in response to hypoxia IMP
IMP: Inferred from mutant phenotype
18270324 RGD
involved in response to inactivity IEP
IEP: Inferred from expression pattern
15638087 RGD
involved in response to insulin IEP
IEP: Inferred from expression pattern
20465785 RGD
involved in response to lead ion IEP
IEP: Inferred from expression pattern
15721881 RGD
involved in response to light intensity IEP
IEP: Inferred from expression pattern
17514533 RGD
involved in response to oxidative stress IDA
IDA: Inferred from direct assay
17576767 RGD
involved in response to ozone IEP
IEP: Inferred from expression pattern
20465785 RGD
involved in response to phenylpropanoid IEP
IEP: Inferred from expression pattern
18547798 RGD
involved in response to reactive oxygen species IMP
IMP: Inferred from mutant phenotype
14713308 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
12225545 RGD
involved in response to vitamin A IEP
IEP: Inferred from expression pattern
23485553 RGD
involved in response to vitamin E IEP
IEP: Inferred from expression pattern
19641679 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
16131024 RGD
involved in ureteric bud development IMP
IMP: Inferred from mutant phenotype
22733796 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
9250541 RGD
located in peroxisomal matrix IDA
IDA: Inferred from direct assay
26961980 RGD
located in peroxisome IDA
IDA: Inferred from direct assay
14561759 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

catalase

Related Agents

Approval
Bioactive Molecules (25)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0988 Deferoxamine mesylate 99.94% Unkown
HY-B1625 Deferoxamine 99.76% Yes
HY-Y0682 Ethylenediaminetetraacetic acid ≥98.0% Unkown
HY-B0193A Prazosin hydrochloride 99.51% Unkown
HY-P0163 Gramicidin Inhibitor ≥98.0% Unkown
HY-B1221 Flufenamic acid 99.93% Unkown
HY-75161 (-)-Menthol Activator 99.79% Unkown
HY-B1836 Meldonium Activator 99.82% Unkown
HY-B1203A Fludrocortisone acetate 99.37% Unkown
HY-N7075 Inulin / Yes
HY-B1213 Trimipramine maleate 99.82% Unkown
HY-109556 Insulin Detemir Activator ≥95.0% Unkown
HY-119572 Sodium zirconium cyclosilicate ≥95.0% Unkown
HY-B0565 Ronidazole Inhibitor 99.79% Unkown
HY-B1836A Meldonium dihydrate Activator ≥99.0% Unkown
HY-B1833 Afloqualone Agonist 99.94% Unkown
HY-103354 Proglumide sodium Antagonist 99.85% Yes
HY-B1330 Proglumide Antagonist 99.84% Yes
HY-B1009 Ethylenediaminetetraacetic acid trisodium salt ≥98.0% Unkown
HY-118874 Oblimersen / Unkown
HY-103354A Proglumide hemicalcium Antagonist / Unkown
HY-16094 Bethanidine sulfate Antagonist / Unkown
HY-B0193AR Prazosin hydrochloride (Standard) / Unkown
HY-B1213A Trimipramine / Unkown
HY-B2143 Montmorillonite / Unkown
Clinical Phase
Bioactive Molecules (17)
Cat. No. Product Name Effect
Purity Phase
HY-N6687 Calcimycin 99.12% Phase 4
HY-Y0682B Ethylenediaminetetraacetic acid tetrasodium ≥98.0% Phase 4
HY-Y0682A Ethylenediaminetetraacetic acid disodium dihydrate 99.9% Phase 4
HY-W105700 Ethylenediaminetetraacetic acid sodium hydrate ≥98.0% Phase 4
HY-N6687A Calcimycin hemicalcium salt / Phase 4
HY-N6687B Calcimycin hemimagnesium / Phase 4
HY-103586 GS-441524 Inhibitor 99.89% Phase 3
HY-142118 Trabedersen Inhibitor 90.45% Phase 3
HY-145728 Alicaforsen Inhibitor / Phase 3
HY-149101 Riboxin / Phase 3
HY-P2141 TRV-120027 Agonist 98.11% Phase 2
HY-P2141A TRV-120027 TFA Agonist 99.69% Phase 2
HY-A0157B Dimethothiazine hydrochloride Antagonist / Phase 2
HY-P10515 AcrAP2 Inhibitor / Phase 2
HY-100973A Adenosine 5′-diphosphoribose sodium 99.03% Phase 1
HY-15533 LY 3000328 Inhibitor 98.00% Phase 1
HY-103586A GS-441524 hydrochloride Inhibitor / Phase 1
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99305 Metelimumab Inhibitor 98.98% Phase 2
HY-P99474 Bertilimumab Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (169)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13434 Ionomycin ≥99.0% Unkown
HY-P1410 GsMTx4 Inhibitor 99.80% Unkown
HY-101840 EIPA 99.73% Unkown
HY-13434A Ionomycin calcium ≥98.0% Unkown
HY-P1410A GsMTx4 TFA Inhibitor 99.80% Unkown
HY-152182 ML-SA5 Agonist 99.57% Unkown
HY-146245 ODN 1826 / Unkown
HY-129555 Surfactin Inhibitor 98.96% Unkown
HY-P1471 Adrenomedullin (AM) (22-52), human Antagonist 99.61% Unkown
HY-B1793 Tetraethylammonium chloride Inhibitor ≥98.0% Unkown
HY-101840A EIPA hydrochloride 98.31% Unkown
HY-14710 AZ3146 Inhibitor 99.92% Unkown
HY-19960 BCTC 98.03% Unkown
HY-100231 Cathepsin inhibitor 1 Inhibitor 99.28% Unkown
HY-19408 Pyr10 Inhibitor 99.42% Unkown
HY-150726 ODN 1668 / Unkown
HY-135869 Mito-apocynin (C11) Inhibitor 99.24% Unkown
HY-120601 Alizarin Red S sodium ≥95.0% Unkown
HY-W040129 Chromomycin A3 Inhibitor 99.66% Unkown
HY-D0193 Ponceau 4R 99.09% Unkown
HY-N1378 (E)-Cardamonin 99.84% Unkown
HY-122605 TRPM4-IN-1 Inhibitor 99.98% Unkown
HY-19976 RN-1747 Agonist 99.25% Unkown
HY-107740 Pseudoisocyanine iodide Inhibitor 99.92% Unkown
HY-W013579 (S)-(+)-Carvone 99.26% Unkown
HY-110374 NVS-CECR2-1 99.40% Unkown
HY-129096 IDT307 99.76% Unkown
HY-112776A BN82002 hydrochloride Inhibitor 99.36% Unkown
HY-146584 Cathepsin C-IN-5 Inhibitor 95.70% Unkown
HY-P2324 Gramicidin A Inhibitor 98.10% Unkown
HY-144256 CHD1Li 6.11 Inhibitor 99.54% Unkown
HY-108460 A-784168 Inhibitor ≥99.0% Unkown
HY-N2003 D-Tetrahydropalmatine Antagonist 99.84% Unkown
HY-P5601A Thanatin TFA Inhibitor 99.51% Unkown
HY-17630 Edasalonexent Inhibitor 99.17% Yes
HY-P1077A CALP1 TFA 99.86% Unkown
HY-131897 1-Stearoyl-2-arachidonoyl-sn-glycerol Activator ≥99.0% Unkown
HY-N6790 Nonactin ≥99.0% Unkown
HY-W014106 Tetraethylammonium tetrafluoroborate ≥98.0% Unkown
HY-W018574 Tetraoctylammonium bromide ≥98.0% Unkown
HY-107535 AS1269574 99.84% Unkown
HY-P2887 Acetate kinase (ACK) / Unkown
HY-160610A Carbamoyl phosphate dilithium salt / Unkown
HY-121065 BN-82685 Inhibitor 99.05% Unkown
HY-135868 Mito-apocynin (C2) Inhibitor 98.38% Unkown
HY-139192 Brophenexin 99.59% Unkown
HY-139192A Brophenexin free base 99.24% Unkown
HY-P1770 Adrenomedullin (16-31), human 98.50% Unkown
HY-W011052 Tetrapentylammonium bromide ≥98.0% Unkown
HY-W011972 Bromocholine bromide ≥98.0% Unkown
HY-117865 GNE-886 Inhibitor 99.81% Unkown
HY-149203A MQA-P TFA 97.36% Unkown
HY-W006212 1,4,7-Triazonane 99.62% Unkown
HY-133825 Cyazofamid Inhibitor 98.08% Unkown
HY-148129 TRPC6-IN-3 Inhibitor 99.62% Unkown
HY-10656 SB-657510 Antagonist 99.84% Unkown
HY-108446 GSK 1562590 hydrochloride Antagonist ≥99.0% Unkown
HY-111527 PPZ2 99.70% Unkown
HY-112776 BN82002 Inhibitor / Unkown
HY-B1221S1 Flufenamic acid-13C6 / Unkown
HY-W011087 Benzyldimethyltetradecylammonium chloride 99.70% Unkown
HY-W014408 Tetraethylammonium bromide ≥98.0% Unkown
HY-W025784 Kalibor 99.62% Unkown
HY-147774 Cathepsin K inhibitor 6 Inhibitor 98.18% Unkown
HY-171152 NSC 357754 Inhibitor / Unkown
HY-76632 4-Hydroxyisophthalic acid Activator 99.51% Unkown
HY-109077 Tigolaner 98.53% Unkown
HY-111297 BMVC4 / Unkown
HY-114671 Taprostene Agonist / Unkown
HY-125870 Gellan gum, for cell culture / Unkown
HY-137155 Dapsone hydroxylamine Inhibitor 94.92% Unkown
HY-E70191 β-1,4-Galactosyltransferase 2 / Unkown
HY-E70387 Ligninase / Unkown
HY-W012450 Trimethylphenylammonium bromide ≥98.0% Unkown
HY-W014536 N,N,N-Trimethyloctan-1-aminium chloride ≥99.0% Unkown
HY-W127701 [Bmpip][NTf2] ≥97.0% Unkown
HY-W127739 Zineb / Unkown
HY-Y0682S EDTA-d12 98.00% Unkown
HY-158222 Alginate Methacryloyl (MW 50000) / Unkown
HY-N8707 Homobutein Inhibitor 98.35% Unkown
HY-W739372 Poly(sodium 4-styrenesulfonate) / Unkown
HY-100057 BMY 28674 Antagonist / Unkown
HY-10290 MK-0674 Inhibitor / Unkown
HY-103216A RWJ52353 hydrochloride Agonist / Unkown
HY-107129 MK-3577 Antagonist / Unkown
HY-107345 Droxicam Inhibitor / Unkown
HY-107644 AQ-RA 741 Antagonist / Unkown
HY-107756 LOE 908 hydrochloride Inhibitor / Unkown
HY-111525 Monactin Inhibitor / Unkown
HY-113778 15-keto-17-phenyl trinor Prostaglandin F2α / Unkown
HY-115371 Butaperazine dimaleate / Unkown
HY-116161 Bimatoprost isopropyl ester / Unkown
HY-116264 CatB-IN-1 / Unkown
HY-116478 L-3373 Inhibitor / Unkown
HY-117774 AHR-2244 hydrochloride / Unkown
HY-117817 Ranelic acid / Unkown
HY-120685 WAY-125971 Antagonist / Unkown
HY-121670 Ambenoxan / Unkown
HY-121670A Ambenoxan hydrochloride / Unkown
HY-124514 UC-857993 Inhibitor / Unkown
HY-126115 15(S)-Latanoprost Inhibitor / Unkown
HY-126763 ATI22-107 Inhibitor / Unkown
HY-129846 IBTP iodide / Unkown
HY-131897S 1-Stearoyl-2-Arachidonoyl-d8-sn-Glycerol Activator / Unkown
HY-136894 Rhod-5N / Unkown
HY-143714 Cathepsin K inhibitor 2 Inhibitor / Unkown
HY-145150 TRPC5-IN-1 Inhibitor / Unkown
HY-146580 Cathepsin C-IN-3 Inhibitor / Unkown
HY-146581 Cathepsin C-IN-4 Inhibitor / Unkown
HY-147186 5,5'-Difluoro BAPTA / Unkown
HY-147333 Trimipramine N-oxide / Unkown
HY-148156 Hydroxydione Inhibitor / Unkown
HY-148162 Kayexalate / Unkown
HY-153613 Ac-PLVE-FMK Inhibitor ≥98.0% Unkown
HY-153614 Ac-VLPE-FMK Inhibitor ≥99.0% Unkown
HY-155254 Sodium ionophore VI / Unkown
HY-156045A Cross-linked dextran G 10 / Unkown
HY-157441 AChE/Aβ-IN-4 Inhibitor / Unkown
HY-157915 HFPB / Unkown
HY-158222A Alginate Methacryloyl (MW 300000) / Unkown
HY-161772 (S)-Gebr32a Inhibitor / Unkown
HY-172387 CM Cross-linked dextran C 25 / Unkown
HY-172387A CM Cross-linked dextran C 50 / Unkown
HY-A0157 Dimethothiazine Antagonist / Unkown
HY-A0157A Dimethothiazine mesylate Antagonist / Unkown
HY-B0565S Ronidazole-d3 Inhibitor / Unkown
HY-B1221S Flufenamic acid-d4 / Unkown
HY-D1640 5',5-Difluoro BAPTA tetrapotassium / Unkown
HY-E70373 λ Protein phosphatase / Unkown
HY-N14351 Ferrocin A Inhibitor / Unkown
HY-N7857 19(R)-Hydroxy-prostaglandin F2α / Unkown
HY-P10228 S-Thanatin Inhibitor / Unkown
HY-P10652 hsBCL9CT-24 Inhibitor / Unkown
HY-P1077 CALP1 98.44% Unkown
HY-P1471A Adrenomedullin (AM) (22-52), human TFA Antagonist / Unkown
HY-P1770A Adrenomedullin (16-31), human TFA / Unkown
HY-P2324A Gramicidin A TFA Inhibitor / Unkown
HY-P3711 SPAI-1 Inhibitor / Unkown
HY-P5601 Thanatin Inhibitor / Unkown
HY-RS01982 CAT Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-W010736A 1,2-Dipalmitoyl-rac-glycerol / Unkown
HY-W011122 Tributylbenzylammonium bromide ≥98.0% Unkown
HY-W013231 N-Benzyl-N,N-diethylethanaminium iodide / Unkown
HY-W075836 Ferrocenylmethyltrimethylammonium iodide / Unkown
HY-W105699 EDTA tetrasodium tetrahydrate ≥97.0% Unkown
HY-Y0682S1 Ethylenediaminetetraacetic acid-d16 / Unkown
HY-106699 Taprostene sodium Agonist / Unkown
HY-116889 15-Keto latanoprost acid / Unkown
HY-124894 (+)-Benalaxyl Inhibitor / Unkown
HY-126605 Trinactin Inhibitor / Unkown
HY-130325 α-Guanidinoglutaric acid Inhibitor / Unkown
HY-134268 8-Br-7-CH-ADPR Antagonist / Unkown
HY-137639 Sp-8-Br-cGMPS Agonist / Unkown
HY-139120 19(R)-hydroxy Prostaglandin E2 / Unkown
HY-148034 Plm IV inhibitor-1 Inhibitor / Unkown
HY-14830 SAR 97276 Inhibitor / Unkown
HY-157240 CEX Ion-exchange resin / Unkown
HY-157241 CEX Cation-exchange resin 1 / Unkown
HY-157242 CEX Polishing resin / Unkown
HY-157243 CEX Cation-exchange resin 2 / Unkown
HY-163073 Anti-MRSA agent 9 Inhibitor / Unkown
HY-168363 Ciclotizolam Ligand / Unkown
HY-170993 Antimicrobial agent-39 Inhibitor / Unkown
HY-D2319 Mito Flipper-TR 27 / Unkown
HY-N9928 Echinenone Inhibitor / Unkown
HY-W013264A Tetrabutylammonium chloride monohydrate / Unkown
HY-W103463 1-Phenyl-2-pyrrolidinone Inhibitor 99.86% Unkown
HY-W654254 Malachite green-d5 oxalate / Unkown
HY-W781133 cDPCP / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99627 Frunevetmab 95.00% Unkown
HY-P99695 Lerdelimumab Inhibitor / Unkown
HY-P990562 CAT-2200 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cat NCBI NCBI:847
Felis catus Cat NCBI NCBI:101093891
Canis lupus familiaris Cat NCBI
Mus musculus Cat NCBI NCBI:12359