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Results for "

coagulation

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Factor VIII (3) Akt (1) Apoptosis (5) Autophagy (5) Bacterial (4) Biochemical Assay Reagents (2) Cholinesterase (ChE) (1) COX (2) DNA/RNA Synthesis (1) Drug Metabolite (1) Elastase (4) Endogenous Metabolite (8) Estrogen Receptor/ERR (1) Factor VIIa (1) Factor Xa (21) HIV (3) Integrin (1) Kallikrein (2) Liposome (1) MMP (1) NF-κB (4) NO Synthase (2) P2Y Receptor (1) PAI-1 (2) Protease Activated Receptor (PAR) (3) Proteasome (2) SARS-CoV (4) Ser/Thr Protease (1) TGF-β Receptor (1) Thrombin (13) Toll-like Receptor (TLR) (1) Tyrosinase (1)
By Research Areas:	Cancer (20) Cardiovascular Disease (38) Infection (7) Inflammation/Immunology (15) Metabolic Disease (2) Neurological Disease (3)
Oligonucleotides:	Solvents (1) Fillers (1) Aptamers (2) Cationic Lipids (1)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Omfiloctocog alfa SCT-800	Factor VIII	Metabolic Disease
Omfiloctocog alfa (SCT-800) is a recombinant factor VIII (FVIII). FVIII is an essential blood coagulation protein and a key component of the fluid phase blood coagulation system. Omfiloctocog alfa can be used for the research of Hemophilia A .

Bismuth subgallate 1 Publications Verification	Factor Xa	Others
Bismuth subgallate, a hemostatic agent, acts on coagulation factor XII (Hageman factor), leading to the activation of the coagulation cascade and improving early formation of a fibrin clot .

D-Pro-Phe-Arg-Chloromethylketone	Factor Xa Kallikrein	Cardiovascular Disease Neurological Disease
D-Pro-Phe-Arg-Chloromethylketone, a inhibitor of coagulation factor XII and plasma kallikrein, plays an important role in thrombosis and inflammation .

Vitamin K4 Acetomenaphthone	Endogenous Metabolite Apoptosis	Cardiovascular Disease Cancer
Vitamin K4 is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system. Vitamin K4 arrests the cells in S phase and induces apoptosis. Vitamin K4 can be used for the research of cancer, such as prostate cancer and osteosarcoma .

Thrombin, Pig blood	Protease Activated Receptor (PAR)	Inflammation/Immunology
Thrombin, Pig blood is a key enzyme in the coagulation cascade, responsible for converting fibrinogen into fibrin. Thrombin, Pig blood activates platelet activation, endothelial cell function, and inflammatory responses by binding to PAR-1 and PAR-4, which triggers G protein-coupled signaling pathways. Thrombin, Pig blood holds promise for research in coagulation and inflammation fields .

Turoctocog alfa	Factor VIII	Others
Turoctocog alfa is a recombinant coagulation factor VIII (FVIII) from chinese hamster ovary (CHO) cells. Turoctocog alfa can be used for researching haemophilia A .

Denecimig Mim8	Factor Xa	Cardiovascular Disease
Denecimig (Mim8) is a novel *activated coagulation* factor VIII**-mimetic human bispecific antibody with anti-FIXa and anti-FX arms that potently stimulates FX activation resulting in efficacious haemostasis in vitro and in vivo .

CM-352	MMP	Cardiovascular Disease
CM-352 (compound 5) is an inhibitor of matrix metalloproteinases (MMPs) (MMP-3: IC₅₀=15 nM; MMP-10: IC₅₀=12 nM). CM-352 has significant antifibrinolytic activity (EC₅₀=0.7 nM) and can significantly prolong blood coagulation time. CM-352 can be used in anti-bleeding research .

Vitamin K4 (Standard)	Endogenous Metabolite Apoptosis	Cardiovascular Disease Cancer
Vitamin K4 (Standard) is the analytical standard of Vitamin K4. This product is intended for research and analytical applications. Vitamin K4 is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system. Vitamin K4 arrests the cells in S phase and induces apoptosis. Vitamin K4 can be used for the research of cancer, such as prostate cancer and osteosarcoma .

Iron(II) D-gluconate dihydrate, 98% D-Gluconic acid iron(II) salt dihydrate, 98%	Biochemical Assay Reagents	Others
Iron(II) D-gluconate dihydrate, 98% is used for blood coagulation.

Vitamin K1 3 Publications Verification Phylloquinone; Phytomenadione	Endogenous Metabolite	Cardiovascular Disease
Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

Dextran Dextran 40	Bacterial	Cardiovascular Disease Cancer
Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander.

Human Factor Xa	Others	Others
Human Factor Xa is a blood coagulation protease. Human Factor Xa is used in research of novel anticoagulant development .

Difethialone LM-2219	Others	Others
Difethialone (LM-2219) is an anticoagulant rodenticide. Difethialone shows high rodenticide activity in warfarin-sensitive and resistant strains of rats and mice. Difethialone interferes with the circulation of vitamin K in the liver, preventing the synthesis of coagulation factors, resulting in the inability of the blood to coagulate properly, ultimately causing internal bleeding and death. Difethialone can be used in studies of ecological impacts .

Efmoroctocog alfa	Factor VIII	Others
Efmoroctocog alfa is a recombinant human coagulation factor VIII-Fc fusion protein (rFVIIIFc) that can be used for the research of haemophilia A .

Vitamin K	Endogenous Metabolite	Cardiovascular Disease
Vitamin K, the blood-clotting vitamin, is important for the function of numerous proteins within the body, such as the coagulation factors, osteocalcin and matrix-Gla protein.

Gabexate mesylate 4 Publications Verification FOY	Proteasome Factor Xa	Inflammation/Immunology
Gabexate mesylate (FOY) is is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. Gabexate mesylate inhibits human thrombin, urokinase, plasmin, and Factor Xa with K_is of 0.97, 1.3, 1.6, and 8.5 μM, respectively. Gabexate mesylate binds to human and bovine tryptase with K_is of 3.4 nM and 18 μM, respectively. Gabexate mesylate exerts an anticoagulant effect on the clotting activity of thrombin and has anti-inflammatory effect by viainhibition of NF-κB, proinflammatory cytokines, and nitric oxide. Gabexate mesylate is used for pancreatitis and disseminated intravascular coagulation .

Fibrin	Others	Cardiovascular Disease Cancer
Fibrin, isolated from bovine blood, is an insoluble protein produced in response to bleeding. Fibrin is the major component of the blood clot and is used for coagulation .

Human Factor XIIa Beta	Others	Others
Human Factor XIIa Beta is the active fragment of coagulation factor XII, that participates in the intrinsic pathway of coagulation, and leads to the formation of blood clots. Human Factor XIIa Beta also participates in the kinin-generating pathway, which leads to the release of bradykinin (vasodilator). Human Factor XIIa Beta stimulates the release of catecholamines, and mediates its cardiovascular effects through a noncholinergic angiotensin-converting enzyme (ACE)-regulated mechanism .

Human Factor XIa	Others	Others
Human Factor XIa is a blood coagulation protease. Human Factor XIa activates the Factor IX and Factor V, resulting in the generation of thrombin and fibrin .

SA-152	Others	Others
SA-152 is an organophosphorus inhibitor. SA-152 modulates the fibrinogen coagulation and TAME esterase activity of bovine α-thrombin .

Gabexate mesylate (Standard)	Proteasome Factor Xa	Inflammation/Immunology
Gabexate (mesylate) (Standard) is the analytical standard of Gabexate (mesylate). This product is intended for research and analytical applications. Gabexate mesylate (FOY) is is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. Gabexate mesylate inhibits human thrombin, urokinase, plasmin, and Factor Xa with Kis of 0.97, 1.3, 1.6, and 8.5 μM, respectively. Gabexate mesylate binds to human and bovine tryptase with Kis of 3.4 nM and 18 μM, respectively. Gabexate mesylate exerts an anticoagulant effect on the clotting activity of thrombin and has anti-inflammatory effect by viainhibition of NF-κB, proinflammatory cytokines, and nitric oxide. Gabexate mesylate is used for pancreatitis and disseminated intravascular coagulation .

Methoxycarbonyl-D-Nle-Gly-Arg-pNA	Factor Xa	Others
Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin that can serve as a substrate for coagulation factors IXa (FIXa) and Xa (FXa) .

EMD 495235	Factor Xa	Cardiovascular Disease
EMD 495235 is a potent and orally active coagulation factor Xa inhibitor with an IC₅₀ of 5.5 nM and a K_i of 6.8 nM. EMD 495235 shows anticoagulant activities .

Difethialone (Standard)	Others	Others
Difethialone (Standard) is the analytical standard of Difethialone. This product is intended for research and analytical applications. Difethialone (LM-2219) is an anticoagulant rodenticide. Difethialone shows high rodenticide activity in warfarin-sensitive and resistant strains of rats and mice. Difethialone interferes with the circulation of vitamin K in the liver, preventing the synthesis of coagulation factors, resulting in the inability of the blood to coagulate properly, ultimately causing internal bleeding and death. Difethialone can be used in studies of ecological impacts .

AS1468240	Factor Xa	Others
AS1468240 is an orally active inhibitor for anticoagulant factor Xa (fXa), that inhibits human fXa with IC₅₀ of 8.7 nM. AS1468240 prolongs the coagulation time in mice .

Bovine fibrinogen (from plasma) FGA; FGA protein	NF-κB	Inflammation/Immunology
Bovine fibrinogen (from fibrinogen) is a native fibrinogen from bovine plasma. Bovine fibrinogen (from fibrinogen) can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 .

Thrombin (MW 37kDa) 5 Publications Verification	Thrombin	Neurological Disease
Thrombin (MW 37kDa) is a Na ⁺-activated, allosteric serine protease that plays opposing functional roles in blood coagulation. Thrombin recognition sequence and can be used to digest GST-tagged proteins.

Vitamin K1 (Standard)	Endogenous Metabolite	Cardiovascular Disease
Vitamin K1 (Standard) is the analytical standard of Vitamin K1. This product is intended for research and analytical applications. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

Human Factor Alpha XIIa	Others	Others
Human Factor Alpha XIIa is a blood coagulation protease, which increases the clotting potential. Human Factor Alpha XIIa exhibits a fibrinolysis protein homologous heavy chain, indicating its function in fibrinolysis .

Heparin sodium salt 35+ Cited Publications Sodium heparin; Sodium heparinate	Thrombin Factor Xa Autophagy	Cardiovascular Disease Cancer
Heparin sodium salt (Sodium heparin) is an anticoagulant which binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. Heparin sodium salt significantly inhibits exosome-cell interactions.

Thrombin Receptor Activator for Peptide 5 (TRAP-5)	Protease Activated Receptor (PAR)	Cardiovascular Disease
Thrombin Receptor Activator for Peptide 5 (TRAP-5) is also called Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), used in the research of coronary heart disease (CHD).

Bovine Factor IXa Beta	Others	Others
Bovine Factor IXa Beta is an inactive and highly specific enzyme, with a minimal extended substrate recognition site and a preference for particular amino acid residues at specific subsites. Bovine Factor IXa Beta plays a role in the blood coagulation cascade .

Asundexian 1 Publications Verification BAY-2433334	Factor Xa	Cardiovascular Disease
Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC₅₀ of 1 nM .

Fostemsavir sodium BMS-663068 sodium	Others	Infection
Fostemsavir sodium (BMS-663068 sodium) is an HIV-1 attachment inhibitor with antiviral activity against multidrug-resistant HIV-1. Co-inhibition with fostemsavir sodium also showed a trend toward reduction in markers of monocyte activation and coagulation abnormalities .

Human α-Thrombin EC 3.4.21.5; Human Alpha Thrombin	Thrombin	Cardiovascular Disease
Human α-thrombin is a multifunctional serine protease that plays a pivotal role in the coagulation pathway. Human α-thrombin cleaves fibrinogen and converts it into fibrin. Human α-thrombin can stimulate platelet activation and stabilize fibrin polymers .

ONO-EI-601	Drug Metabolite	Others
ONO-EI-601 is the major metabolite of human neutrophil elastase inhibitor ONO-5046. ONO-5046 has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .

Scutellarein tetramethyl ether 1 Publications Verification 4',5,6,7-Tetramethoxyflavone	Bacterial COX NO Synthase NF-κB	Infection Inflammation/Immunology Cancer
Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is a bioactive compound extracted from Eupatorium odoratum. Scutellarein tetramethyl ether exhibits anti-inflammatory, antibacterial, pro-coagulant, and anti-tumor activities. Scutellarein tetramethyl ether exerts its anti-inflammatory effects by modulating the NF-κB pathway and regulates bacterial resistance through the inhibition of efflux pumps. Additionally, Scutellarein tetramethyl ether accelerates coagulation time via the endogenous coagulation pathway. Studies have shown that Scutellarein tetramethyl ether can effectively inhibit the growth of the liver cancer cell line HepG2 (IC₅₀= 20.08 μg/mL) .

Sivelestat 15+ Cited Publications EI546; LY544349; ONO5046	Elastase SARS-CoV	Cancer
Sivelestat (EI546) is a competitive inhibitor of human neutrophil elastase, with an IC₅₀ of 44 nM and a K_i of 200 nM. Sivelestat (EI546) has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .

Sivelestat sodium 15+ Cited Publications ONO5046-Na; Sodium sivelestat; EI546 sodium; LY544349 sodium	Elastase SARS-CoV	Cancer
Sivelestat (EI546) sodium is a competitive inhibitor of human neutrophil elastase, with an IC₅₀ of 44 nM and a K_i of 200 nM. Sivelestat (EI546) sodium has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19 .

Benzoyloxypaeoniflorin	Tyrosinase NF-κB	Inflammation/Immunology
Benzoyloxypaeoniflorin, isolated from the root of Paeonia suffruticosa, is a tyrosinase inhibitor against mushroom tyrosinase with IC₅₀ of 0.453 mM. Benzoyloxypaeoniflorin is NF-κB Inhibitor and contributes to improving blood circulation through its inhibitory effect on both platelet aggregation and blood coagulation .

TM5007	PAI-1	Inflammation/Immunology Cancer
TM5007 is a poent and orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) with an IC₅₀ of 29 μM. TM5007 enhance fibrinolysis activity and inhibits coagulation. TM5007 also prevents the fibrotic process initiated by bleomycin in mouse lung .

Cat. No.	Product Name

HY-L136

Coagulation and Anti-coagulation Compound Library

1,034 compounds

Coagulation, also known as clotting, is the process in which blood changes from a liquid to a solid gel to form a blood clot. Thrombin, which is accurately and evenly generated in the injured part of blood vessels, is a key effector enzyme of the blood coagulation system and participates in many important biological processes, such as platelet activation, fibrinogen conversion to fibrin network, coagulation feedback amplification, etc. At the same time, to avoid the accidental formation of thrombus in the body, there is also an anticoagulant mechanism that inhibits blood coagulation.

Normal coagulation mechanism represents a balance between the pro-coagulant pathway in the injured site and anti-coagulant pathway beyond it. The blood coagulation system may be out of balance during the perioperative period or critical illness, which may lead to thrombosis or excessive bleeding. Therefore, the physiological study of coagulation balance is an important basis for clinical diagnosis and treatment of the abnormal coagulation process.

MCE supplies a unique collection of 1,034 compounds targeting key proteins in coagulation and anti-coagulation system. MCE Coagulation and Anti-coagulation Compound Library is a useful tool for study the mechanism of coagulation and anticoagulation.

HY-L193

PBCRBS Traditional Chinese Medicine Compound Library

1,063 compounds

Since ancient times, promoting blood circulation for removing blood stasis (PBCRBS) has been one of the most popular research contents in the area of traditional Chinese medicine (TCM) and integrated medicine. Rhizoma, Persicae Semen, Carthami Flos, Curcumae Longae Rhizoma and so on are common TCM with PBCRBS characteristic. Studies have shown that the mechanism of action of PBCRBS TCM is to promote blood circulation (improving cardiovascular and cerebrovascular functions, physical and chemical properties of blood, platelet and coagulation system and other physiological functions) and remove blood stasis (anti-myocardial ischemia, cerebral ischemia, inhibition of platelet aggregation, anti-coagulation, anti-thrombosis, etc.). Not only that, PBCRBS TCM has anti-infection, inhibit inflammation, regulate immune function, inhibit immune response, inhibit abnormal tissue proliferation and other functions. Therefore, PBCRBS TCM has high research value in all- field disease research fields.

MCE can supply 1,063 monomer component from more than a hundred sources of PBCRBS TCM, which can be used in TCM studies, drug development and mechanism-based studies.

HY-L197

Vitamin Compound Library

143 compounds

Vitamins are a category of trace organic compounds essential for maintaining normal physiological functions in living organisms. They are classified into fat-soluble and water-soluble vitamins. Fat-soluble vitamins play a role in maintaining vision, bone health, reproductive functions, and blood coagulation. Water-soluble vitamins are involved in energy metabolism, nervous system function, and cellular repair processes. Most vitamins cannot be synthesized by the organism and must be obtained through diet. In recent years, vitamins and their derivatives have become increasingly important in the field of drug development due to their extensive physiological activities. Additionally, vitamins and their derivatives can be used to construct research platforms for vitamin metabolism, which helps to delve into the metabolic pathways and dynamic changes of vitamins within the body and aids in identifying new biomarkers for certain diseases.

MCE included 143 vitamins and their derivatives, including Vitamin A, Vitamin B, Vitamin D, etc., which is a good tool for studying vitamin metabolism.

Cat. No.	Product Name	Type

HY-112624

Dextran Dextran 40	Drug Delivery
Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander.

HY-145405

C12-200 5+ Cited Publications	Drug Delivery
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .

HY-116282

Dextran sulfate sodium salt (MW 5000)

1 Publications Verification

DSS (MW 5000); DXS (MW 5000)

Carbohydrates

Dextran sulfate sodium salt (MW 5000) is a polymer of anhydroglucose with a molecular weight of 5000. Dextran sulfate sodium salt (MW 5000) can be used to induce acute colitis and cause apoptosis of colonic epithelial cells in mice. The concentration dose used in the study was 5% (in feed, w/w). The sulfated polysaccharide dextran sulfate is also an effective inhibitor of HIV. Dextran sulfate sodium salt (MW 5000) can significantly inhibit HIV-1 replication at a concentration that does not significantly inhibit the blood coagulation process. Dextran sulfate sodium salt (MW 5000) protects MT-4 cells from HIV-1-induced cellular pathogenicity. Dextran sulfate-induced colitis can be inhibited by Puerarin (HY-N0145), Baicalein (HY-N0196), β-Caryophyllene (HY-N1415).

HY-W105875

Iron(II) D-gluconate dihydrate, 98% D-Gluconic acid iron(II) salt dihydrate, 98%	Chelators
Iron(II) D-gluconate dihydrate, 98% is used for blood coagulation.

HY-NP018

Bovine fibrinogen (from plasma) FGA; FGA protein	Native Proteins
Bovine fibrinogen (from fibrinogen) is a native fibrinogen from bovine plasma. Bovine fibrinogen (from fibrinogen) can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 .

HY-126944

2-Aminobenzanilide 2-Amino-N-phenylbenzamide	Indicators
2-Aminobenzamide is a neutral and stable compound used as fluorescent tag, numerously in Glycan analysis. 2-aminobenzamide acts as the starting material for several important reactions like Bargellini reaction as an competent ambident nucleophile. Specifically 2-aminobenzamide and its derivatives are used in the blood coagulation cascade .

Cat. No.	Product Name	Target	Research Area

HY-P4245

D-Pro-Phe-Arg-Chloromethylketone	Factor Xa Kallikrein	Cardiovascular Disease Neurological Disease
D-Pro-Phe-Arg-Chloromethylketone, a inhibitor of coagulation factor XII and plasma kallikrein, plays an important role in thrombosis and inflammation .

HY-P3235

E-76	Peptides	Others
E-76 is a peptide with anticoagulant activity. E-76 inhibits blood coagulation by specifically binding to exogenous coagulation factor VIIa (FVIIa). E-76 can be used to study blood coagulation-related diseases .

HY-P4908

S-(1,2-Dicarboxyethyl)glutathione	Peptides	Cardiovascular Disease
S-(1,2-Dicarboxyethyl)glutathione is a peptide that inhibits blood coagulation and platelet aggregation .

HY-P4576

Methoxycarbonyl-D-Nle-Gly-Arg-pNA	Factor Xa	Others
Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin that can serve as a substrate for coagulation factors IXa (FIXa) and Xa (FXa) .

HY-P1536

Thrombin Receptor Activator for Peptide 5 (TRAP-5)	Protease Activated Receptor (PAR)	Cardiovascular Disease
Thrombin Receptor Activator for Peptide 5 (TRAP-5) is also called Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), used in the research of coronary heart disease (CHD).

HY-P5372

Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2	Protease Activated Receptor (PAR)	Others
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biological active peptide. (Protease activated receptor 1 (PAR-1) belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. This peptide is a PAR-1 selective agonist displaying a high level of specificity to PAR-1 over PAR-2. The specificity of peptide was evaluated in cell-based calcium signaling assay using HEK293 cells. PAR-1 selective agonists can be used to study PAR-1 activation in vivo. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type'.)

Cat. No.	Product Name	Target	Research Area

HY-P99769

Omfiloctocog alfa SCT-800	Factor VIII	Metabolic Disease
Omfiloctocog alfa (SCT-800) is a recombinant factor VIII (FVIII). FVIII is an essential blood coagulation protein and a key component of the fluid phase blood coagulation system. Omfiloctocog alfa can be used for the research of Hemophilia A .

HY-112935

Nonacog alfa BAX326; coagulation Factor IX [Recombinant]	Inhibitory Antibodies	Others
Nonacog alfa (BAX326) is a recombinant human factor IX that can be used for the research of haemophilia B .

HY-P990060

Denecimig Mim8	Factor Xa	Cardiovascular Disease
Denecimig (Mim8) is a novel *activated coagulation* factor VIII**-mimetic human bispecific antibody with anti-FIXa and anti-FX arms that potently stimulates FX activation resulting in efficacious haemostasis in vitro and in vivo .

HY-112998

Efmoroctocog alfa	Factor VIII	Others
Efmoroctocog alfa is a recombinant human coagulation factor VIII-Fc fusion protein (rFVIIIFc) that can be used for the research of haemophilia A .

Species:	Human (12) Mouse (6) Rat (2) Cynomolgus (2) Rabbit (2) Pig (2) Canine (1)
Tag:	His (25) SUMO (1) Fc (2)
Source:	HEK293 (22) CHO (1) P. pastoris (1) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P73045

	Coagulation Factor VII/F7 Protein, Mouse (CHO, His) coagulation factor VII; Eptacog alfa; F7; FVII coagulation protein; SPCA	Mouse	CHO
	Coagulation Factor VII (F7) protein lacks crucial conserved residue(s) needed for propagating feature annotation. Coagulation Factor VII/F7 Protein, Mouse (CHO, His) is the recombinant mouse-derived Coagulation Factor VII/F7 protein, expressed by CHO , with C-His labeled tag. The total length of Coagulation Factor VII/F7 Protein, Mouse (CHO, His) is 422 a.a., with molecular weight of 56-63 kDa.

HY-P74239

	Coagulation Factor VII/F7 Protein, Human (HEK293, His) coagulation factor VII; Eptacog alfa; F7; FVII coagulation protein; SPCA	Human	HEK293
	Coagulation factor VII (F7) initiates the extrinsic pathway of blood coagulation. As a circulating zymogen, F7 is activated to F7a through proteolysis induced by factor Xa, factor XIIa, factor IXa, or thrombin. In the presence of tissue factor and calcium ions, F7a catalyzes limited proteolysis of factor X, converting it to factor Xa. F7a can also convert factor IX to factor IXa, emphasizing its pivotal role in coagulation cascades. Coagulation Factor VII/F7 Protein, Human (HEK293, His) is the recombinant human-derived Coagulation Factor VII/F7 protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor VII/F7 Protein, Human (HEK293, His) is 406 a.a., with molecular weight of ~50 kDa.

HY-P72189

	Coagulation Factor XII/F12 Protein, Pig (His) F12 coagulation factor XII; EC 3.4.21.38; Hageman factor; HAF; coagulation factor XIIa heavy chain; coagulation factor XIIa light chain	Pig	E. coli
	Coagulation factor XII (F12) is a serum glycoprotein that plays multiple roles in initiating blood coagulation, fibrinolysis, and the production of bradykinin and angiotensin. It is involved in these complex processes, including cleavage of prekallikrein to form kallikrein, which subsequently cleaves factor XII initially to α-factor XIIa and then, after trypsin cleavage, to β-factor XIIa. Coagulation Factor XII/F12 Protein, Pig (His) is the recombinant pig-derived Coagulation Factor XII/F12 protein, expressed by E. coli , with N-6*His labeled tag. The total length of Coagulation Factor XII/F12 Protein, Pig (His) is 352 a.a., with molecular weight of ~43.8 kDa.

HY-P72944

	Coagulation Factor II/F2 Protein, Mouse (HEK293, His) Prothrombin; coagulation factor II	Mouse	HEK293
	Coagulation Factor II/F2, also known as thrombin, functions as a pivotal serine protease. Its enzymatic action involves cleaving bonds after Arg and Lys residues, facilitating the conversion of fibrinogen to fibrin. Thrombin additionally activates key factors like V, VII, VIII, XIII, and, in conjunction with thrombomodulin, protein C. Beyond blood homeostasis, thrombin plays a role in inflammation and the complex dynamics of wound healing. Coagulation Factor II/F2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Coagulation Factor II/F2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor II/F2 Protein, Mouse (HEK293, His) is 594 a.a., with molecular weight of ~85 kDa.

HY-P74241

	Coagulation Factor II/F2 Protein, Rat (HEK293, His) Prothrombin; coagulation factor II	Rat	HEK293
	The factor II/F2 protein (also known as thrombin) plays a key role in blood homeostasis, inflammation, and wound healing. As a multifunctional enzyme, it catalyzes the conversion of fibrinogen into fibrin to form the coagulation network. Coagulation Factor II/F2 Protein, Rat (HEK293, His) is the recombinant rat-derived Coagulation Factor II/F2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P72188

	Coagulation Factor XI/F11 Protein, Human (His) coagulation factor XI; coagulation factor XIa light chain; F11; FA11_HUMAN; FXI; MGC141891; Plasma thromboplastin antecedent; Platelet coagulation factor XI ; PTA	Human	E. coli
	Coagulation factor XI (F11) occupies a central position in the middle phase of the intrinsic pathway of blood coagulation, where it assumes the key role of activating factor IX. This complex process plays a key role in the chain of events that lead to the formation of a blood clot. Coagulation Factor XI/F11 Protein, Human (His) is the recombinant human-derived Coagulation Factor XI/F11 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70231

	Coagulation factor IX/F9 Protein, Human (HEK293, His) rHucoagulation factor IX/F9, His; F9; coagulation factor IX; Christmas factor; Plasma thromboplastin component; coagulation factor IXa light chain; coagulation factor IXa heavy chain	Human	HEK293
	Factor IX (F9) is a vitamin K-dependent plasma protein that plays a critical role in the intrinsic pathway of coagulation. Factor IX coordinates the conversion of factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa. Coagulation factor IX/F9 Protein, Human (HEK293, His) is the recombinant human-derived Coagulation factor IX/F9 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P700565

	Coagulation factor VII/F7 Protein, Human (His-SUMO) coagulation factor VII; Eptacog alfa; F7; FVII coagulation protein; SPCA	Human	E. coli
	Coagulation factor VII (F7) initiates the extrinsic pathway of blood coagulation. As a circulating zymogen, F7 is activated to F7a through proteolysis induced by factor Xa, factor XIIa, factor IXa, or thrombin. In the presence of tissue factor and calcium ions, F7a catalyzes limited proteolysis of factor X, converting it to factor Xa. F7a can also convert factor IX to factor IXa, emphasizing its pivotal role in coagulation cascades. Coagulation factor VII/F7 Protein, Human (His-SUMO) is the recombinant human-derived Coagulation factor VII/F7 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

HY-P73046

	Coagulation Factor XI/F11 Protein, Human (HEK293, His) coagulation factor XI; coagulation factor XIa light chain; PTA; FXI; F11	Human	HEK293
	Coagulation factor XI (F11) occupies a central position in the middle phase of the intrinsic pathway of blood coagulation, where it assumes the key role of activating factor IX. This complex process plays a key role in the chain of events that lead to the formation of a blood clot. Coagulation Factor XI/F11 Protein, Human (HEK293, His) is the recombinant human-derived Coagulation Factor XI/F11 protein, expressed by HEK293 , with C-His labeled tag.

HY-P700599

	Coagulation Factor XII/F12 Protein, Pig (P. pastoris, His) F12 coagulation factor XII; EC 3.4.21.38; Hageman factor; HAF; coagulation factor XIIa heavy chain; coagulation factor XIIa light chain	Pig	P. pastoris
	Coagulation factor XII (F12) is a serum glycoprotein that plays multiple roles in initiating blood coagulation, fibrinolysis, and the production of bradykinin and angiotensin. It is involved in these complex processes, including cleavage of prekallikrein to form kallikrein, which subsequently cleaves factor XII initially to α-factor XIIa and then, after trypsin cleavage, to β-factor XIIa. Coagulation Factor XII/F12 Protein, Pig (P. pastoris, His) is the recombinant pig-derived F12/Coagulation Factor XII, Pig, expressed by P. pastoris , with N-6*His labeled tag.

HY-P74240

	Coagulation Factor IX/F9 Protein, Mouse (HEK293, His) coagulation Factor IX; F9; FIX; HEMB; PTC	Mouse	HEK293
	Coagulation Factor IX/F9 Protein, a vital vitamin K-dependent plasma protein, is pivotal in the intrinsic blood coagulation pathway. Its role includes converting factor X into its active form, a process facilitated by Ca(2+) ions, phospholipids, and factor VIIIa. Coagulation Factor IX/F9 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Coagulation Factor IX/F9 protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor IX/F9 Protein, Mouse (HEK293, His) is 471 a.a., with molecular weight of 60-95 kDa.

HY-P700978

	Coagulation Factor XI/F11 Protein, Cynomolgus (HEK293, His) FXI; PTA; F11; coagulation factor XI	Cynomolgus	HEK293
	Coagulation factor XI (F11) occupies a central position in the middle phase of the intrinsic pathway of blood coagulation, where it assumes the key role of activating factor IX. This complex process plays a key role in the chain of events that lead to the formation of a blood clot. Coagulation Factor XI/F11 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Coagulation Factor XI/F11 protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor XI/F11 Protein, Cynomolgus (HEK293, His) is 607 a.a., with molecular weight of 70-85 kDa.

HY-P74238

	Coagulation factor XIII B/F13B Protein, Human (HEK293, His) coagulation factor XIII B chain; F13B	Human	HEK293
	Coagulation factor XIII B/F13B Proteinas, the B chain of factor XIII, lacks catalytic activity but stabilizes A subunits and regulates thrombin-initiated transglutaminase formation. Functioning as a tetramer with two A chains (F13A1) and two B chains (F13B), it structurally supports the factor XIII complex, emphasizing its regulatory role in blood coagulation, particularly in transglutaminase activation by thrombin. Coagulation factor XIII B/F13B Protein, Human (HEK293, His) is the recombinant human-derived Coagulation factor XIII B/F13B protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation factor XIII B/F13B Protein, Human (HEK293, His) is 641 a.a., with molecular weight of 80-90 kDa.

HY-P70215

	Coagulation Factor X/F10 Protein, Mouse (HEK293, His) rMucoagulation factor X/FX, His; F10; coagulation factor X; Stuart factor	Mouse	HEK293
	Coagulation Factor X/F10 Protein, a crucial vitamin K-dependent glycoprotein, is central to blood clotting. It produces Factor Xa, essential for converting prothrombin to thrombin, a process facilitated by factor Va, calcium, and phospholipid in the intricate cascade of blood coagulation. Coagulation Factor X/F10 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Coagulation Factor X/F10 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Coagulation Factor X/F10 Protein, Mouse (HEK293, His) is 461 a.a., with molecular weight of ~55.0 kDa.

HY-P7860

	Coagulation Factor X/F10 Protein, Human (HEK293, Fc) rHucoagulation Factor X/F10, Fc; coagulation factor X; Stuart factor; Stuart-Prower factor	Human	HEK293
	Factor X (F10) is a vitamin K-dependent glycoprotein that plays a key role in the blood coagulation process as factor Xa. Factor Xa, along with factor Va, calcium, and phospholipids, coordinates the conversion of prothrombin to thrombin, a key step in the coagulation cascade. Coagulation Factor X/F10 Protein, Human (HEK293, Fc) is the recombinant human-derived Coagulation Factor X/F10 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Coagulation Factor X/F10 Protein, Human (HEK293, Fc) is 457 a.a., with molecular weight of 80-130 & 25 kDa, respectively.

HY-P700695

	Coagulation Factor III/F3 Protein, Canine (HEK293, His) Tissue factor; coagulation Factor III; TF; Thromboplastin; CD142; F3; FLJ17960; TFA	Canine	HEK293
	Coagulation Factor III (F3), or Tissue Factor (TF), initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex critically activates factors IX or X through limited proteolysis, initiating the coagulation cascade on the cell surface. F3's interaction with HSPE, inhibited by heparin, promotes the generation of activated factor X, emphasizing its central role in regulating hemostatic processes. Coagulation Factor III/F3 Protein, Canine (HEK293, His) is the recombinant canine-derived Coagulation Factor III/F3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor III/F3 Protein, Canine (HEK293, His) is 214 a.a., with molecular weight of 35-45 kDa.

HY-P70226

	Coagulation factor XIII A/F13A Protein, Human (HEK293, His) rHucoagulation factor XIII A chain/F13A, His; coagulation Factor XIII A Chain; coagulation Factor XIIIa; Protein-Glutamine Gamma-Glutamyltransferase A Chain; Transglutaminase A Chain; F13A1; F13A	Human	HEK293
	Coagulation factor XIII A chain is the A chain of factor XIII. As a coagulation factor, Factor XIII A chain alters clot stabilization and bleeding. Factor XIII A chain regulates multiple aspects of wound healing: stabilizes fibrin clots and extracellular matrix, modulates monocyte functions, promote angiogenesis, and upregulates proangiogenic early growth response transcription factor 1. Coagulation factor XIII A/F13A Protein, Human (HEK293, His) is the recombinant human-derived Coagulation factor XIII A/F13A protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Coagulation factor XIII A/F13A Protein, Human (HEK293, His) is 694 a.a., with molecular weight of 80-90 kDa.

HY-P74236

	Coagulation Factor XIV/PROC Protein, Mouse (HEK293, His) Vitamin K-dependent protein C; APC; Protein C; PROC	Mouse	HEK293
	Factor XIV/PROC protein (or protein C) is an important vitamin K-dependent serine protease that regulates blood clotting.Protein C plays a crucial role in inactivating factors Va and VIIIa and regulating the coagulation cascade in the presence of calcium ions and phospholipids.Coagulation Factor XIV/PROC Protein, Mouse (HEK293, His) is the recombinant mouse-derived Coagulation Factor XIV/PROC protein, expressed by HEK293 , with C-His labeled tag.

HY-P74237

	Coagulation Factor XIV/PROC Protein, Human (HEK293, His) Vitamin K-dependent protein C; APC; Protein C; PROC	Human	HEK293
	Coagulation Factor XIV/PROC is a vital vitamin K-dependent serine protease regulating blood coagulation. Active Protein C inactivates factors Va and VIIIa in the presence of calcium ions and phospholipids, maintaining the intricate balance of coagulation pathways. Its protective effect on endothelial cell barrier function underscores a broader impact on vascular integrity. Coagulation Factor XIV/PROC Protein, Human (HEK293, His) is the recombinant human-derived Coagulation Factor XIV/PROC protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor XIV/PROC Protein, Human (HEK293, His) is 443 a.a., with molecular weight of 56-64 & 45 kDa, respectively.

HY-P71127

	Tissue Factor Protein, Mouse (HEK293, His) Tissue factor; TF; coagulation factor III;	Mouse	HEK293
	Tissue factor (TF) initiates blood coagulation by forming a complex with circulating factor VII or VIIa, thus forming the [TF:VIIa] complex. This complex is capable of specific limited proteolysis of factors IX or X and plays a key role in normal hemostasis by initiating the coagulation protease cascade. Tissue Factor Protein, Mouse (HEK293, His) is the recombinant mouse-derived Tissue Factor protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Tissue Factor Protein, Mouse (HEK293, His) is 223 a.a., with molecular weight of 35-42 kDa.

HY-P78592

	Tissue Factor Protein, Cynomolgus (HEK293, His) coagulation Factor III; Tissue Factor; TF; F3; CD142	Cynomolgus	HEK293
	F3 Protein, a cell surface receptor, plays a significant role in regulating blood coagulation and promoting cell adhesion. Dysregulation of F3 Protein has been associated with various disorders, including thrombosis and cancer. Targeting F3 Protein may offer potential therapeutic interventions in these conditions by inhibiting blood clot formation and preventing tumor cell adhesion and metastasis. Tissue Factor Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Tissue Factor protein, expressed by HEK293 , with C-His labeled tag.

HY-P73592

	Tissue Factor Protein, Rat (HEK293, His) CD142; coagulation Factor III; F3; TF; TFA; Tissue Factor	Rat	HEK293
	Tissue Factor Protein plays a critical role in blood coagulation.It binds to coagulation factors, activating clotting cascades.Tissue Factor Protein interacts with cells, promoting thrombosis and inflammation.Understanding its functions can aid in developing treatments for blood disorders and cardiovascular diseases.Tissue Factor Protein, Rat (HEK293, His) is the recombinant rat-derived Tissue Factor protein, expressed by HEK293 , with C-His labeled tag.

HY-P73594

	Tissue Factor Protein, Rabbit (HEK293, His) CD142; coagulation Factor III; F3; TF; TFA; Tissue Factor	Rabbit	HEK293
	Tissue Factor Protein initiates blood coagulation by binding to coagulation factors. It activates clotting cascades and interacts with cells to promote thrombosis and inflammation. Understanding Tissue Factor Protein's functions is crucial for developing treatments for cardiovascular diseases and blood disorders. Tissue Factor Protein, Rabbit (HEK293, His) is the recombinant Rabbit-derived Tissue Factor protein, expressed by HEK293 , with C-His labeled tag. The total length of Tissue Factor Protein, Rabbit (HEK293, His) is 218 a.a., with molecular weight of ~26.4 kDa.

HY-P7787

	Tissue Factor Protein, Human (HEK293, His) rHuCD142, His; Tissue Factor; TF; coagulation Factor III; Thromboplastin; CD142; F3	Human	HEK293
	Tissue Factor Protein, Human (HEK293, His) is a recombinant human CD142 expressed in HEK 293 cells with a His tag at the C-terminus. Coagulation Factor III/CD142 Protein is a principal regulator of oncogenic neoangiogenesis and controls therefore the cancerous process.

HY-P7787A

	Tissue Factor Protein, Human (HEK293, Fc) rHuCD142, His; Tissue Factor; TF; coagulation Factor III; Thromboplastin; CD142; F3	Human	HEK293
	Tissue Factor Protein, Human (HEK293, Fc) is a recombinant human CD142 expressed in HEK 293 cells with a Fc tag at the C-terminus. Coagulation Factor III/CD142 Protein is a principal regulator of oncogenic neoangiogenesis and controls therefore the cancerous process.

HY-P700431

	TFPI Protein, Rabbit (HEK293, His) TFPI; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); LACI; tissue factor pathway inhibitor; EPI; extrinsic pathway inhibitor; TFI; TFPI1; anti-convertin	Rabbit	HEK293
	TFPI Protein inhibits factor X (Xa) directly and, in an Xa-dependent manner, hinders the activity of VIIa/tissue factor, possibly by forming a quaternary complex with Xa, TFPI, VIIa, and tissue factor. This multifunctional protein has antithrombotic properties and associates with lipoproteins in plasma, highlighting its crucial role in regulating the coagulation pathway. TFPI Protein, Rabbit (HEK293, His) is the recombinant Rabbit-derived TFPI protein, expressed by HEK293 , with N-10*His labeled tag. The total length of TFPI Protein, Rabbit (HEK293, His) is 276 a.a., with molecular weight of 55 kDa.

HY-P70095

	DCBLD2 Protein, Human (HEK293, His) rHuDiscoidin, CUB and LCCL domain-containing protein 2/ DCBLD2, His; Discoidin; CUB and LCCL domain-containing protein 2; DCBLD2; CUB; LCCL and coagulation factor V/VIII-homology domains protein 1; Endothelial and smooth muscle cell-derived neuropilin-like protein; DCBLD2; CLCP1; ESDN;	Human	HEK293
	DCBLD2 Protein is a novel platelet membrane receptor that recruits TRAF6 through EGFR phosphorylation and stimulates AKT to promote tumorigenesis. The DCBLD2 Protein has multiple functions during development as well as in vascular and tumor biology, such as influencing cell proliferation and tumorigenesis. DCBLD2 Protein, Human (HEK293, His) is the recombinant human-derived DCBLD2 protein, expressed by HEK293 , with C-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-B1192S

Estradiol benzoate-d3
Estradiol benzoate-d₃ is the deuterium labeled Estradiol benzoate. Estradiol Benzoate (β-Estradiol 3-benzoate), a proagent of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability[1][2][3][4].

HY-N0684S3

Vitamin K1-13C6
Vitamin K1- ¹³C₆ is the ¹³C-labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-N0684S

Vitamin K1-d7
Vitamin K1-d₇ is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1][2].

HY-N0684S1

Vitamin K1-d4
Vitamin K1-d₄ is the deuterium labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism[1].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81886

	Factor XIIIa Antibody (YA1631) coagulation factor XIIIa; F13A; F13a1; Fibrin stabilizing factor; A subunit; Fibrinoligase; TGase; Transglutaminase A chain	WB, IHC-P	Human
	Factor XIIIa Antibody (YA1631) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1631), targeting Factor XIIIa, with a predicted molecular weight of 83 kDa (observed band size: 83 kDa). Factor XIIIa Antibody (YA1631) can be used for WB, IHC-P experiment in human background.

HY-P81608

	Factor IX Antibody (YA1353) coagulation factor IX; Christmas factor; Plasma thromboplastin component; PTC [Cleaved into: coagulation factor IXa light chain; coagulation factor IXa heavy chain]	WB	Human
	Factor IX Antibody (YA1353) is a biotin-conjugated non-conjugated IgG antibody, targeting Factor IX, with a predicted molecular weight of 52 kDa (observed band size: 52 kDa). Factor IX Antibody (YA1353) can be used for WB experiment in human background.

HY-P81243

	F2 Antibody Des-gamma-carboxy (abnormal)prothrombin; Des-Gamma-carboxy-prothrombin; coagulation factor II (thrombin); coagulation factor II; DCP; Factor II; Prepro coagulation factor II; Prothrombin; prothrombin B-chain; PT; RPRGL2; serine protease; THPH1; THRB; THRB_HUMAN; Thrombin heavy chain.	WB, IP	Human
	F2 Antibody is a biotin-conjugated non-conjugated IgG antibody, targeting F2, with a predicted molecular weight of 70 kDa (observed band size: 76 kDa). F2 Antibody can be used for WB, IP experiment in human background.

HY-P82726

	Tissue Factor Antibody (YA2471) F3; Tissue factor; TF; coagulation factor III; Thromboplastin; CD antigen CD142	WB, IHC-P	Human, Mouse, Rat
	Tissue Factor Antibody (YA2471) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2471), targeting Tissue Factor, with a predicted molecular weight of 33 kDa (observed band size: 45 kDa). Tissue Factor Antibody (YA2471) can be used for WB, IHC-P experiment in human, mouse, rat background.

HY-P82716

	Protein C Antibody (YA2461) PROC; Vitamin K-dependent protein C; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV	WB	Human
	Protein C Antibody (YA2461) is a biotin-conjugated non-conjugated IgG antibody, targeting Protein C, with a predicted molecular weight of 52 kDa (observed band size: 52 kDa). Protein C Antibody (YA2461) can be used for WB experiment in human background.

HY-P81604

	Factor X Antibody (YA1349) Activated factor Xa heavy chain; coagulation factor X; F10; factor Xa; FXA; Prothrombinase; Stuart factor	WB, IHC-P	Human
	Factor X Antibody (YA1349) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1349), targeting Factor X, with a predicted molecular weight of 55 kDa (observed band size: 74 kDa). Factor X Antibody (YA1349) can be used for WB, IHC-P experiment in human background.

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Cat. No.	Product Name		Classification

HY-112624

Dextran Dextran 40		Fillers
Dextran (Dextran 40) has an inhibitory effect on thrombocyte aggregation and coagulation factors and is used as a plasma volume expander.

HY-145405

C12-200 5+ Cited Publications		Cationic Lipids
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .

HY-Y0320

Dimethyl sulfoxide 130+ Cited Publications DMSO		Solvents
Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties . MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition).

HY-153836

Anivamersen		Aptamers
Anivamersen is an RNA aptamer to reverse the anticoagulant effect of the parenteral factor IXa inhibitor pegnivacogin. REG1 is a novel anticoagulation system consisting of pegnivacogin, an RNA aptamer inhibitor of coagulation factor IXa, and anivamersen, a complementary sequence reversal oligonucleotide.

HY-153836A

Anivamersen sodium		Aptamers
Anivamersen sodium is an RNA aptamer to reverse the anticoagulant effect of the parenteral factor IXa inhibitor pegnivacogin. REG1 is a novel anticoagulation system consisting of pegnivacogin, an RNA aptamer inhibitor of coagulation factor IXa, and anivamersen, a complementary sequence reversal oligonucleotide.

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