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Results for "

elicitor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) ADC Cytotoxin (1) Antibiotic (1) Antibody-Drug Conjugates (ADCs) (1) Apoptosis (8) Aurora Kinase (1) Autophagy (1) Bacterial (5) Beta-secretase (1) Biochemical Assay Reagents (1) Calcium Channel (4) Caspase (1) CaSR (4) CDK (1) Checkpoint Kinase (Chk) (1) Cholecystokinin Receptor (1) Complement System (2) CXCR (1) Cytochrome P450 (1) Deubiquitinase (2) Dopamine Receptor (1) EBV (1) Endogenous Metabolite (2) Endothelin Receptor (5) ERK (1) Estrogen Receptor/ERR (2) Ferroptosis (1) Filovirus (1) FLAP (1) Fungal (1) GABA Receptor (1) GHSR (1) Guanylate Cyclase (1) HBV (1) HDAC (2) HSP (1) Influenza Virus (2) Integrin (2) Keap1-Nrf2 (1) Ligands for E3 Ligase (1) Mas-related G-protein-coupled Receptor (MRGPR) (2) MDM-2/p53 (1) Melanocortin Receptor (1) mGluR (1) Monocarboxylate Transporter (2) nAChR (1) NF-κB (2) NOD-like Receptor (NLR) (1) p38 MAPK (1) Parasite (1) PARP (1) PD-1/PD-L1 (1) PERK (1) PKC (2) Polo-like Kinase (PLK) (1) Potassium Channel (1) Prostaglandin Receptor (2) PROTACs (1) Proteasome (2) RAR/RXR (1) Reactive Oxygen Species (5) ROCK (1) ROS Kinase (1) SOD (1) Sodium Channel (2) SphK (1) Src (1) STAT (1) STING (2) TNF Receptor (1) Toll-like Receptor (TLR) (5) TRP Channel (2) VEGFR (1) Virus Protease (1) Wnt (2) α-synuclein (1)
By Research Areas:	Cancer (38) Cardiovascular Disease (10) Endocrinology (6) Infection (13) Inflammation/Immunology (25) Metabolic Disease (10) Neurological Disease (26)
Oligonucleotides:	Phospholipids (1) Antisense Oligonucleotides (2)

112

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N3570

Cerebroside B	Fungal	Infection
Cerebroside B, a sphingolipid compound, is a non-racespecific elicitor, which elicits defense responses in rice .

HY-10624

THIQ 1 Publications Verification	Melanocortin Receptor	Metabolic Disease
THIQ is the first selective agonist of the melanocortin-4 receptor (MC4R), with high affinity and potency for hMC4R (IC₅₀=1.2 nM, EC₅₀=2.1 nM) and rMC4R (IC₅₀=0.6 nM, EC₅₀=2.9 nM). THIQ maintains low potency at MC1R, MC3R and MC5R. THIQ plays a role in eliciting erectile activity in rodents. THIQ acts as a pharmacoperone of the MC4R rescuing the cell surface expression and signaling of some intracellularly retained MC4R mutants .

HY-N7697

Chitotetraose tetrahydrochloride	Others	Others
Chitotetraose tetrahydrochloride is an arbuscular mycorrhizal (AM) fungal short-chain chitin oligomer. Chitotetraose tetrahydrochloride activates the AM fungal-dependent conserved symbiosis signaling pathway (CSSP) in actinorhizal plant species .

HY-N3171

Nortrachelogenin (-)-Wikstromol; (-)-Nortrachelogenin	Apoptosis	Cancer
Nortrachelogenin ((-)-Wikstromol) from Partrinia scabiosaefolia elicits an apoptotic response in Candida albicans .

HY-103223

Phortress NSC 710305	Cytochrome P450	Cancer
Phortress is a high affinity AhR ligand that elicits antitumor activity by inducing transcription of CYP1A1 .

HY-N8491A

(+)-Dihydrocarvone	Others	Others
(+)-Dihydrocarvone elicits strong antennal responses of A. mellifera. (+)-Dihydrocarvone influences bee foraging preference for tomato .

HY-118120

GEMSA 2-Guanidinoethylmercaptosuccinic acid	Others	Neurological Disease
GEMSA is a potent inhibitor of enkephalin convertase (K_i=8.8 nM). GEMSA elicites analgesia .

HY-W780808

(E)-10-Dodecenol	Others	Endocrinology
(E)-10-Dodecenol is a sex pheromone capable of eliciting electroantennographic responses in male pea moths .

HY-P1568

Flagelin 22 Flagellin 22	Bacterial	Infection
Flagelin 22 (Flagellin 22), a fragment of bacterial flagellin, is an effective elicitor in both plants and algae .

HY-123664

Trioxifene mesylate LY133314	Others	Endocrinology
Trioxifene mesylate (LY133314) is an antiestrogenic compound. Trioxifene mesylate elicits mixed agonist-antagonist actions on estrogen target tissues .

HY-P0278

RGD 5+ Cited Publications	Integrin	Cancer
RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.

HY-P0278A

RGD Trifluoroacetate 5+ Cited Publications	Integrin	Cancer
RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to integrins.

HY-P1568A

Flagelin 22 TFA 3 Publications Verification Flagellin 22 TFA	Bacterial	Infection
Flagelin 22 TFA (Flagellin 22 TFA), a fragment of bacterial flagellin, is an effective elicitor in both plants and algae .

HY-135412

N-Methyl Duloxetine hydrochloride	Sodium Channel	Neurological Disease
N-Methyl Duloxetine hydrochloride is an analgesic. N-Methyl Duloxetine (hydrochloride) elicits both tonic and use-dependent block of neuronal Na ⁺ channels .

HY-N7698A

Penta-N-acetylchitopentaose	Others	Inflammation/Immunology
Penta-N-acetylchitopentaose elicits plant defense systems. Penta-N-acetylchitopentaose is a substrate for the Rhizobium leguminosarum nodulation protein NodL .

HY-119240

CCT020312 Maximum Cited Publications 24 Publications Verification	PERK Autophagy	Neurological Disease Cancer
CCT020312 is a selective EIF2AK3/PERK activator. CCT020312 elicits EIF2A phosphorylation in cells.

HY-139785

Cavrotolimod AST-008	Toll-like Receptor (TLR)	Others Cancer
Cavrotolimod is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.

HY-139785A

Cavrotolimod sodium AST-008 sodium	Toll-like Receptor (TLR)	Others
Cavrotolimod sodium is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.

HY-N10377

Anhuienoside B	Others	Others
Anhuienoside B is a natural product that can be isolated from the fresh leaves of C. anhuiensis K. F. Wu in response to abiotic stress elicitation by CuCl₂ .

HY-18719A

Endoxifen Z-isomer hydrochloride 3 Publications Verification	Estrogen Receptor/ERR Potassium Channel	Cancer
Endoxifen Z-isomer hydrochloride is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ERα).

HY-139716

IMD-catechol	NF-κB	Inflammation/Immunology
IMD-catechol is a novel imidazoquinolinone-NF-κB immunomodulator dimer that improves efficacy in a CT26 mouse colon carcinoma tumor model while eliciting minimal adjuvant toxicity.

HY-155494

trans-Stilbene-NHCO-(CH2)3-acid	Others	Inflammation/Immunology
trans-Stilbene-NHCO-(CH2)3-acid, a trans-stilbene hapten, can be used to elicit a panel of monoclonal antibodies that display a range of fluorescent spectral behavior .

HY-P10663

EBV EBNA3A (379-387)	EBV	Infection Inflammation/Immunology
EBV EBNA3A (379-387) is an antigenic epitope that may elicit the latent-specific CD8 ⁺ T cell response in HLA-B*07:02 ⁺ individuals .

HY-125648

Euphorbadienol alpha-Euphorbol	Parasite	Infection
Euphorbadienol (alpha-Euphorbol), a triterpenic compound, isolated from the latex of Euphorbia resinifera. The derivatives of Euphorbadienol can be used as elicitors of disease resistance, and has antileishmanial and antitrypanosomal activity .

HY-U00441

DPBQ 1 Publications Verification	MDM-2/p53 Apoptosis	Cancer
DPBQ activates p53 and triggers apoptosis in a polyploid-specific manner, but does not inhibit topoisomerase or bind DNA. DPBQ elicits expression and phosphorylation of p53 and this effect is specific to tetraploid cells .

HY-123963

C-178 4 Publications Verification	STING	Inflammation/Immunology
C-178 is a potent and selective covalent inhibitor of STING. C-178 binds to Cys91 and suppresses the STING responses elicited by distinct bona fide activators in mouse but not human .

HY-120989

Methyl 7(Z)-hexadecenoate	Others	Metabolic Disease
Methyl 7(Z)-hexadecenoate is a sex pheromone produced by Trogoderma glabrum. Methyl 7(Z)-hexadecenoate can elicit attractive and sexually excitatory responses in Trogoderma glabrum males .

HY-138794

XL177A	Deubiquitinase	Cancer
XL177A is a highly potent and selective irreversible USP7 inhibitor with an IC₅₀ of 0.34 nM. XL177A elicits cancer cell killing through a p53-dependent mechanism .

HY-N8804

Shatavarin IV Asparanin B	Reactive Oxygen Species	Neurological Disease Cancer
Shatavarin IV is a steroidal saponin, that can be isolated from the roots of Asparagus racemosus (Liliaceae). Shatavarin IV shows anticancer activity. Shatavarin IV elicits lifespan extension and alleviates Parkinsonism in Caenorhabditis elegans .

HY-162108

Antitumor agent-128	Apoptosis	Cancer
Antitumor agent-128 (compound 1a) is an antitumor agent that elicits cell cycle arrest in both the G2/M and S phases, triggering apoptosis in A549 cells .

HY-N0647

Silychristin 1 Publications Verification	Monocarboxylate Transporter	Endocrinology
Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC₅₀ of 110 nM .

HY-W087988

3-Pentanol	Bacterial	Infection
3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants .

HY-132247

ErSO	Others	Cancer
ErSO is a selective anticipatory unfolded protein response (a-UPR) activator. ErSO acts through ERα to elicit strong and sustained cytotoxic activation of the a-UPR. ErSO can be used for the research of cancer .

HY-P5930

HOXB7 8–25 MDM2 32-46	Ligands for E3 Ligase	Cancer
HOXB7 8–25 (MDM2 32-46) is an MDM2-derived peptide epitope and can elicit antigen-specifc and tumor-reactive CD4 ⁺ T cell responses .

HY-N0020

Echinacoside 5+ Cited Publications	Wnt Reactive Oxygen Species	Neurological Disease
Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche deserticola, effectively inhibits Wnt/β-catenin signaling. Echinacoside elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Antiosteoporotic activity .

HY-19608

GSK1016790A 20+ Cited Publications	TRP Channel Calcium Channel	Cardiovascular Disease Metabolic Disease
GSK1016790A is a potent and selective transient receptor potential vanilloid 4 (TRPV4) channel agonist. GSK1016790A can elicit Ca ²⁺ influx and elevate intracellular Ca ²⁺ in HEK cells .

HY-N0699

Daphnoretin 1 Publications Verification Dephnoretin; Thymelol	PKC Influenza Virus	Infection
Daphnoretin (Dephnoretin), isolated from Wikstroemia indica, possesses antiviral activity . Daphnoretin likes PMA, may direct activation of protein kinase C which in turn activated NADPH oxidase and elicited respiratory burst .

HY-P3563

[Lys4] Sarafotoxin S6c	Endothelin Receptor	Cardiovascular Disease
[Lys4] Sarafotoxin S6c, a sarafotoxin analogue, is a potent and partial agonist of endothelin receptor. [Lys4] Sarafotoxin S6c elicits contraction of pig coronary artery, with an EC₅₀ of 1.5 nM .

HY-151971

Aurora Kinases-IN-3	Aurora Kinase Polo-like Kinase (PLK)	Cancer
Aurora Kinases-IN-3 (Compound 15a) is an orally active AURKB inhibitor that elicits an AURKB-suppressive activity by disrupting the mitotic localization of AURKB, rather than inhibiting its phosphorylation of H3 at Ser10 .

HY-N12277

Celosin K	Apoptosis	Neurological Disease
Celosin K (compound 8) can be isolated from the seeds of Semen Celosiae. Celosin K is a potent inhibitor of neuron injury elicited by t-BHP. Celosin K inhibits oxidative stress and apoptosis, and acts of autophagy .

HY-145056

ART615	Others	Cancer
ART615 is the related isomer of ART558. ART615, the inactive of ART558, elicits <10% Polθ inhibition at 12 µM, thus serving as a control for ART558 (IC₅₀=7.9 nM) .

HY-153556

GW297361	CDK VEGFR Src	Others
GW297361 is an oxindole CDK inhibitor that elicits a Pho85-selective response in cells. GW297361 inhibits yeast Cdk1 and Pho85 with IC₅₀s of 20 nM and 400 nM in vitro, respectively .

HY-18779

PF-4840154 1 Publications Verification	TRP Channel	Inflammation/Immunology
PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel with EC₅₀s of 97 and 23 nM, respectively. PF-4840154 elicits TrpA1-mediated nocifensive behaviour in mouse .

HY-156174

E104	Toll-like Receptor (TLR) ADC Cytotoxin	Cancer
E104 (compound 1) is a potent and selective TLR7 agonist. E104 can be delivered by antibody-drug conjugate (ADC) technology to elicit potent anticancer activity. E104 induces the activation of mouse macrophages and hPBMCs .

HY-12825

BHPI	Estrogen Receptor/ERR	Cancer
BHPI is a potent inhibitor of nuclear estrogen–ERα-regulated gene expression; elicits sustained ERα-dependent activation of the endoplasmic reticulum (EnR) stress sensor, the unfolded protein response (UPR), and persistent inhibition of protein synthesis.

HY-N7698

Tetra-N-acetylchitotetraose	Others	Inflammation/Immunology
Tetra-N-acetylchitotetraose elicits plant defense systems. Tetra-N-acetylchitotetraose is a component of the hpo-chitoo gosacchaπdes (LCOs) secreted from Rhizobia. Tetra-N-acetylchitotetraose is also a substrate for the Rhizobium leguminosarum nodulation protein NodB, a CO deacetylase .

HY-N7698B

Hexa-N-acetylchitohexaose	Others	Inflammation/Immunology Cancer
Hexa-N-acetylchitohexaose is an inducer of disease resistance in crop plants, which could elicit an increase of lignification-related and antioxidative enzymes in soybean plants. Hexa-N-acetylchitohexaose is a substrate of lysozyme. Hexa-N-acetylchitohexaose shows antitumor effect .

HY-D1190

DC271	RAR/RXR	Inflammation/Immunology
DC271 is a RAR agonist that can be considered a retinoid, eliciting cellular responses consistent with the endogenous retinoid ATRA and the synthetic retinoid EC23. DC271 binds to retinoid protein machinery, including CRABPII, to translocate the endogenous retinoid ATRA into the nucleus .

HY-19711

STING agonist-1 2 Publications Verification G10	STING Virus Protease	Infection
STING agonist-1 (G10) is human-specific STING agonist that elicits antiviral activity against emerging Alphaviruses. G10 potently blocks replication of Alphavirus species Venezuelan Equine Encephalitis Virus (VEEV) with IC₉₀ of 24.57 μM .

HY-122783

Isogambogic acid	Antibiotic	Cancer
Isogambogic acid is an antibiotic and anti-cancer agent which efficiently elicit cell death in LLC and SK-LU-1 within a low micromolar range with IC₅₀s of 2.26 μM and 2.02 μM. Isogambogic acid can be used for cancer research .

Cat. No.	Product Name	Type

HY-D1190

DC271	Fluorescent Dyes/Probes
DC271 is a RAR agonist that can be considered a retinoid, eliciting cellular responses consistent with the endogenous retinoid ATRA and the synthetic retinoid EC23. DC271 binds to retinoid protein machinery, including CRABPII, to translocate the endogenous retinoid ATRA into the nucleus .

Cat. No.	Product Name	Type

HY-NP003

Collagen, Type II, from bovine snout membrane 1 Publications Verification Collagen	Native Proteins
Collagen, Type II, from bovine snout membrane is a type II collagen that can induce osteoarthritis by eliciting a strong and sustained T cell response. Type II collagen can be used to model collagen-induced arthritis in mice .

Cat. No.	Product Name	Target	Research Area

HY-P0278

RGD Maximum Cited Publications 6 Publications Verification	Integrin	Cancer
RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.

HY-P0278A

RGD Trifluoroacetate Maximum Cited Publications 6 Publications Verification	Integrin	Cancer
RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to integrins.

HY-P1568A

Flagelin 22 TFA 3 Publications Verification Flagellin 22 TFA	Bacterial	Infection
Flagelin 22 TFA (Flagellin 22 TFA), a fragment of bacterial flagellin, is an effective elicitor in both plants and algae .

HY-P2642

Peptide 78	Peptides	Inflammation/Immunology
Peptide 78, a chemotactic cytokine, a 78 amino acid protein member of the IL-8 or C-X-C chemokine supergene family. ENA-78 plays an important role in the elicitation of predominantly neutrophils (PMNs) into the joints of rheumatoid arthritis (RA) .

HY-P1568

Flagelin 22 Flagellin 22	Bacterial	Infection
Flagelin 22 (Flagellin 22), a fragment of bacterial flagellin, is an effective elicitor in both plants and algae .

HY-110183

Angiotensin A	Peptides	Cardiovascular Disease
Angiotensin A is a renin–angiotensin system (RAS) peptide that causes a vasoconstrictive effect dependent on AT₁ receptors. Angiotensin A elicits pressor and renal vasoconstrictor responses in normotensive and hypertensive rats .

HY-P10663

EBV EBNA3A (379-387)	EBV	Infection Inflammation/Immunology
EBV EBNA3A (379-387) is an antigenic epitope that may elicit the latent-specific CD8 ⁺ T cell response in HLA-B*07:02 ⁺ individuals .

HY-P10637

Orcokinin	Peptides	Others
Orcokinin (NFDEIDRSGFGFN) is a crustacean peptide eliciting potent myotropic effects in gut tissues. The first Orcokinin reported was NFDEIDRSGFGFN, isolated from abdominal nerve cord extracts of the crayfish Orconectes limosus .

HY-P5930

HOXB7 8–25 MDM2 32-46	Ligands for E3 Ligase	Cancer
HOXB7 8–25 (MDM2 32-46) is an MDM2-derived peptide epitope and can elicit antigen-specifc and tumor-reactive CD4 ⁺ T cell responses .

HY-P3563

[Lys4] Sarafotoxin S6c	Endothelin Receptor	Cardiovascular Disease
[Lys4] Sarafotoxin S6c, a sarafotoxin analogue, is a potent and partial agonist of endothelin receptor. [Lys4] Sarafotoxin S6c elicits contraction of pig coronary artery, with an EC₅₀ of 1.5 nM .

HY-P5453

CFP10 (71–85)	Peptides	Others
CFP10 (71–85) is a biological active peptide. (CFP1071–85, that elicited IFN-γ production and CTL activity by both CD4+ and CD8+ T cells from persons expressing multiple MHC class II and class I molecules)

HY-W650842

Boc-Asp(OBzl)-CMK	Caspase	Cancer
Boc-Asp(OBzl)-CMK is an inhibitor for IL-1 converting enzyme (ICE, caspase1). Boc-Asp(OBzl)-CMK prevents death of CHP100 neuroblastoma cell, and IL-1β release elicited by the viral coat protein .

HY-P3419

PAMP-12 (unmodified)	Mas-related G-protein-coupled Receptor (MRGPR)	Cardiovascular Disease
PAMP-12 (unmodified) is a potent MRGPRX2 (MrgX2) agonist (EC₅₀=20-50 nM). PAMP-12 (unmodified) is an endogenous peptide that elicit hypotension through inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells .

HY-P3419A

PAMP-12 (unmodified) (TFA)	Mas-related G-protein-coupled Receptor (MRGPR)	Cardiovascular Disease
PAMP-12 (unmodified) TFA is a potent MRGPRX2 (MrgX2) agonist (EC₅₀=20-50 nM). PAMP-12 (unmodified) is an endogenous peptide that elicit hypotension through inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells .

HY-P1112

Sarafotoxin S6a	Endothelin Receptor	Cardiovascular Disease Neurological Disease
Sarafotoxin S6a, a sarafotoxin analogue, is a endothelin receptor agonist and has an ET_A/ET_B selectivity profile similar to that of Endothelin-3 (HY-P0204). Sarafotoxin S6a elicits the pig coronary artery with an EC₅₀ value of 7.5 nM .

HY-P5782

δ-Theraphotoxin-Hm1a toxin	Sodium Channel	Neurological Disease
δ-Theraphotoxin-Hm1a toxin is a selective Na_v1.1 activator. δ-Theraphotoxin-Hm1a toxin elicits pain and touch sensitivity. δ-Theraphotoxin-Hm1a toxin can be used for the research of irritable bowel syndrome .

HY-P1112A

Sarafotoxin S6a TFA	Endothelin Receptor	Cardiovascular Disease Neurological Disease
Sarafotoxin S6a TFA , a sarafotoxin analogue, is a endothelin receptor agonist and has an ET_A/ET_B selectivity profile similar to that of Endothelin-3 (HY-P0204). Sarafotoxin S6a TFA elicits the pig coronary artery with an EC₅₀ value of 7.5 nM .

HY-P10400

AtPep1	Peptides	Inflammation/Immunology
AtPep1 is a plant elicitor peptide. AtPep1 activates transcription of the defensive gene defensin (PDF1.2) and activates the synthesis of H₂O₂, which are components of the innate immune response against pathogens. AtPep1 can be isolated from extracts of Arabidopsis leaves .

HY-P4042

Hepatitis B Virus Receptor Binding Fragment hepatitis B peptide 4980	HBV	Infection Inflammation/Immunology
Hepatitis B Virus Receptor Binding Fragment (hepatitis B peptide 4980) is a synthetic peptide analog which specifically binds to Hep G2 cells. Hepatitis B Virus Receptor Binding Fragment is a promising immunogen expected to elicit protective antibodies based on the concept of the attachment blockade pathway of virus neutralization .

HY-P1016

BQ-3020	Endothelin Receptor	Cardiovascular Disease
BQ-3020 is a selective endothelin receptor (ET_B receptor) agonist that displaces [ ¹²⁵I] ET-1 binding to ET_B receptors, with an IC₅₀ value of 0.2 nM. BQ-3020 elicits vasoconstriction in the rabbit pulmonary artery. BQ-3020 makes relaxation of the pig urinary bladder neck and can be used for cardiovascular disease research ¹ ².

HY-P1016B

BQ-3020 ammonium	Endothelin Receptor	Cardiovascular Disease
BQ-3020 ammonium is a selective endothelin receptor (ET_B receptor) agonist. BQ-3020 ammonium inhibits [ ¹²⁵I] ET-1 binding to ET_B receptors, with an IC₅₀ value of 0.2 nM. BQ-3020 ammonium elicits vasoconstriction in the rabbit pulmonary artery. BQ-3020 ammonium makes relaxation of the pig urinary bladder neck and can be used for cardiovascular disease research . .

HY-P4846

Ac-Pro-Gly-Pro-OH	CXCR	Inflammation/Immunology
Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and can be used as CXCR2 agonist. Ac-Pro-Gly-Pro-OH elicits bactericidal activity and inhibits lung inflammation, reducing immune cell apoptosis. Ac-Pro-Gly-Pro-OH enhances the production of type 1 cytokines (IFN-γ and IL-12) but inhibits the production of proinflammatory cytokines. Ac-Pro-Gly-Pro-OH has the potential for the research of sepsis .

HY-P10639

C5aR2 agonist P32	Complement System	Inflammation/Immunology
C5aR2 agonist P32 (Ac-RHYPYWR-OH) is a C5aR2-selective agonist. C5aR2 agonist P32 has been shown to elicit multiple immunomodulatory activities, both by down-regulating the C5aR1-mediated cell signalling, and acting in a C5aR1-independent fashion, in vitro and in vivo .

HY-P10639A

C5aR2 agonist P32 acetate	Complement System	Inflammation/Immunology
C5aR2 agonist P32 (Ac-RHYPYWR-OH) acetate is a C5aR2-selective agonist. C5aR2 agonist P32 acetate has been shown to elicit multiple immunomodulatory activities, both by down-regulating the C5aR1-mediated cell signalling, and acting in a C5aR1-independent fashion, in vitro and in vivo .

HY-P1080

ω-Agatoxin IVA	Calcium Channel	Neurological Disease
ω-Agatoxin IVA is a potent, selective P/Q type Ca ²⁺ (Cav2.1) channel blocker with IC₅₀s of 2 nM and 90 nM for P-type and Q-type Ca ²⁺ channels, respectively. ω-Agatoxin IVA (IC₅₀, 30-225 nM) inhibits glutamate exocytosis and calcium influx elicited by high potassium. ω-Agatoxin IVA also blocks the high potassium-induced release of serotonin and norepinephrine. ω-Agatoxin IVA has no effect on L-type or N-type calcium channels .

HY-P1080A

ω-Agatoxin IVA TFA	Calcium Channel	Neurological Disease
ω-Agatoxin IVA TFA is a potent, selective P/Q type Ca ²⁺ (Cav2.1) channel blocker with IC₅₀s of 2 nM and 90 nM for P-type and Q-type Ca ²⁺ channels, respectively. ω-Agatoxin IVA TFA (IC₅₀, 30-225 nM) inhibits glutamate exocytosis and calcium influx elicited by high potassium. ω-Agatoxin IVA TFA also blocks the high potassium-induced release of serotonin and norepinephrine. ω-Agatoxin IVA TFA has no effect on L-type or N-type calcium channels .

HY-P5502

Influenza NP (311-325)	Peptides	Others
Influenza NP (311-325) is a biological active peptide. (This peptide is amino acids 311 to 325 fragment of the influenza virus nucleoprotein (NP). This bona fide MHC class II restricted epitope from influenza virus was used to study the host immunoresponse during the infection. This peptide elicits the strongest gamma interferon (IFN-gamma) production in the intracellular cytokine assays. It does not stimulate CD8 T-cells in mice.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)

Cat. No.	Product Name	Target	Research Area

HY-P99276

Abagovomab Anti-Human CA-125 Recombinant Antibody	Inhibitory Antibodies	Cancer
Abagovomab (Anti-Human CA-125 Recombinant Antibody) is a murine monoclonal anti-idiotypic antibody, against the tumor-associated antigen, CA-125. Abagovomab is generated by a mouse hybridoma, can imitate the human TAA, CA-125. Abagovomab can elicit humoral and cellular immune responses against ovarian cancer (oc) .

HY-P99683

Ladiratuzumab vedotin SGN-LIV1A	Antibody-Drug Conjugates (ADCs)	Cancer
Ladiratuzumab vedotin (SGN-LIV1A) is a LIV-1 targeting antibody drug conjugate (ADC) (IC₅₀: 5.6 nM for LIV-1). Ladiratuzumab vedotin consists of humanized IgG1 monoclonal antibody, MMAE and a protease-cleavable linker. Ladiratuzumab vedotin can drive immunogenic cell death (ICD) to elicit an immune response. Ladiratuzumab vedotin can be used for research of breast cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N3570

Cerebroside B	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Fungal
Cerebroside B, a sphingolipid compound, is a non-racespecific elicitor, which elicits defense responses in rice .

HY-N7697

Chitotetraose tetrahydrochloride	Polysaccharides Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields Saccharides	Others
Chitotetraose tetrahydrochloride is an arbuscular mycorrhizal (AM) fungal short-chain chitin oligomer. Chitotetraose tetrahydrochloride activates the AM fungal-dependent conserved symbiosis signaling pathway (CSSP) in actinorhizal plant species .

HY-N3171

Nortrachelogenin (-)-Wikstromol; (-)-Nortrachelogenin	Structural Classification Natural Products other families Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	Apoptosis
Nortrachelogenin ((-)-Wikstromol) from Partrinia scabiosaefolia elicits an apoptotic response in Candida albicans .

HY-N0647

Silychristin 1 Publications Verification	Structural Classification Classification of Application Fields Source classification Cyamopsis tetragonoloba (L.) Taub. Plants Compositae Flavanonols Flavonoids Glycine soya Phenols Polyphenols Disease Research Fields Endocrinology	Monocarboxylate Transporter
Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC₅₀ of 110 nM .

HY-W087988

3-Pentanol	Infection Structural Classification Natural Products Animals Classification of Application Fields Source classification Disease Research Fields	Bacterial
3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants .

HY-N8491A

(+)-Dihydrocarvone	Structural Classification Endopappus macrocarpus Sch.Bip. Terpenoids Labiatae Sesquiterpenes Source classification Plants	Others
(+)-Dihydrocarvone elicits strong antennal responses of A. mellifera. (+)-Dihydrocarvone influences bee foraging preference for tomato .

HY-W780808

(E)-10-Dodecenol	Structural Classification Natural Products Animals Source classification	Others
(E)-10-Dodecenol is a sex pheromone capable of eliciting electroantennographic responses in male pea moths .

HY-125648

Euphorbadienol alpha-Euphorbol	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Euphorbia wallichii Euphorbiaceae Plants Disease Research Fields	Parasite
Euphorbadienol (alpha-Euphorbol), a triterpenic compound, isolated from the latex of Euphorbia resinifera. The derivatives of Euphorbadienol can be used as elicitors of disease resistance, and has antileishmanial and antitrypanosomal activity .

HY-120989

Methyl 7(Z)-hexadecenoate	Structural Classification Natural Products Animals Source classification	Others
Methyl 7(Z)-hexadecenoate is a sex pheromone produced by Trogoderma glabrum. Methyl 7(Z)-hexadecenoate can elicit attractive and sexually excitatory responses in Trogoderma glabrum males .

HY-N8804

Shatavarin IV Asparanin B	Structural Classification Natural Products Source classification Plants Asparagaceae Juss.	Reactive Oxygen Species
Shatavarin IV is a steroidal saponin, that can be isolated from the roots of Asparagus racemosus (Liliaceae). Shatavarin IV shows anticancer activity. Shatavarin IV elicits lifespan extension and alleviates Parkinsonism in Caenorhabditis elegans .

HY-N0020

Echinacoside Maximum Cited Publications 10 Publications Verification	Structural Classification Simple Phenylpropanols Cistanche deserticola Ma Source classification Phenols Polyphenols Orobanchaceae Phenylpropanoids Plants	Wnt Reactive Oxygen Species
Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche deserticola, effectively inhibits Wnt/β-catenin signaling. Echinacoside elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Antiosteoporotic activity .

HY-N0699

Daphnoretin 1 Publications Verification Dephnoretin; Thymelol	Infection Structural Classification Monophenols Classification of Application Fields Thymelaeaceae Source classification Coumarins Phenols Phenylpropanoids Plants Disease Research Fields Wikstroemia indica	PKC Influenza Virus
Daphnoretin (Dephnoretin), isolated from Wikstroemia indica, possesses antiviral activity . Daphnoretin likes PMA, may direct activation of protein kinase C which in turn activated NADPH oxidase and elicited respiratory burst .

HY-N12277

Celosin K	Structural Classification Celosia argentea Linn. Polysaccharides Source classification Amaranthaceae Plants Saccharides	Apoptosis
Celosin K (compound 8) can be isolated from the seeds of Semen Celosiae. Celosin K is a potent inhibitor of neuron injury elicited by t-BHP. Celosin K inhibits oxidative stress and apoptosis, and acts of autophagy .

HY-122783

Isogambogic acid	Structural Classification Xanthones Source classification Guttiferae Phenols Plants Garcinia hanburyi Hook. f.	Antibiotic
Isogambogic acid is an antibiotic and anti-cancer agent which efficiently elicit cell death in LLC and SK-LU-1 within a low micromolar range with IC₅₀s of 2.26 μM and 2.02 μM. Isogambogic acid can be used for cancer research .

HY-N2166

Tomatine α-Tomatine; Lycopersicin; Tomatin	Structural Classification Source classification Solanum lycopersicum L. Solanaceae Plants Steroids	Proteasome Apoptosis
Tomatine is a glycoalkaloid, found in the tomato plant (Lycopersicon esculentum Mill.). Tomatine elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine promotes the upregulation of nuclear apoptosis inducing factor (AIF) in neuroblastoma cells. Tomatine also inhibits 20S proteasome activity .

HY-121252

Dopal	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite Reactive Oxygen Species α-synuclein
Dopal is an aldehyde that can be generated in Parkinson's disease by enzymatic degradation of dopamine. Dopal can generate reactive oxygen species, and triggers aggregation of α-synuclein. DOPAL elicits α-synuclein accumulation and hampers α-synuclein clearance in primary neurons .

HY-N0647R

Silychristin (Standard)	Flavanonols Structural Classification Flavonoids Glycine soya Source classification Phenols Polyphenols Cyamopsis tetragonoloba (L.) Taub. Plants Compositae	Monocarboxylate Transporter
Silychristin (Standard) is the analytical standard of Silychristin. This product is intended for research and analytical applications. Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM .

HY-W780787

(E,Z)-3,13-Octadecadienyl acetate E3,Z13-18:Ac	Structural Classification Natural Products Animals Source classification	Others
(E,Z)-3,13-Octadecadienyl acetate (E3,Z13-18:Ac) is an insect sex pheromone that elicits attraction in male lesser peachtree borers (Lesser Peachtree Borer), which can be isolated from female lesser peachtree borers .

HY-N0020R

Echinacoside (Standard)	Structural Classification Simple Phenylpropanols Cistanche deserticola Ma Source classification Phenols Polyphenols Orobanchaceae Phenylpropanoids Plants	Wnt Reactive Oxygen Species
Echinacoside (Standard) is the analytical standard of Echinacoside. This product is intended for research and analytical applications. Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche deserticola, effectively inhibits Wnt/β-catenin signaling. Echinacoside elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Antiosteoporotic activity .

HY-N0699R

Daphnoretin (Standard)	Structural Classification Monophenols Thymelaeaceae Source classification Coumarins Phenols Phenylpropanoids Plants Wikstroemia indica	PKC Influenza Virus
Daphnoretin (Standard) is the analytical standard of Daphnoretin. This product is intended for research and analytical applications. Daphnoretin (Dephnoretin), isolated from Wikstroemia indica, possesses antiviral activity . Daphnoretin likes PMA, may direct activation of protein kinase C which in turn activated NADPH oxidase and elicited respiratory burst .

HY-W087988R

3-Pentanol (Standard)	Structural Classification Natural Products Animals Source classification	Bacterial
3-Pentanol (Standard) is the analytical standard of 3-Pentanol. This product is intended for research and analytical applications. 3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants .

HY-N0394R

L-Cystine (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Source classification Amino acids Endogenous metabolite	Endogenous Metabolite Ferroptosis ROS Kinase Keap1-Nrf2
L-Cystine (Standard) is the analytical standard of L-Cystine. This product is intended for research and analytical applications. L-Cystine, the extracellular form of L-Cysteine (HY-Y0337), is a nutritionally dispensable semiessential sulfur-containing amino acid, occurring in proteins of plants and animals. L-Cystine induces Nrf2 protein elevation in a Keap1 (HY-P75897)-dependent manner and activates Nrf2 transcription factor. L-cystine can elicit cytoprotection by reducing ROS generation and protecting against oxidant- or doxorubicin-induced apoptosis. The reduced reabsorption of L-Cystine in renal tubules and its poor solubility in urine are the important causes of cystine precipitation and cystine crystal formation eventually leading to kidney stones. L-Cystine combined with L-theanine (HY-15121) enhances the production of antigen-specific IgG by increasing glutathione (GSH) levels and T helper 2 (Th2) mediated responses in mice. L-Cystine is promising for research of cystinuria and cystinosis

Cat. No.	Product Name	Chemical Structure

HY-W087988S

3-Pentanol-d5
3-Pentanol-d₅ is the deuterium labeled 3-Pentanol[1]. 3-Pentanol is an active organic compound produced by plants and is a component of emitted insect sex pheromones. 3-pentanol elicits plant immunity against microbial pathogens and an insect pest in crop plants[2].

Cat. No.	Product Name		Classification

HY-139785

Cavrotolimod AST-008		Antisense Oligonucleotides
Cavrotolimod is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.

HY-139785A

Cavrotolimod sodium AST-008 sodium		Antisense Oligonucleotides
Cavrotolimod sodium is an immunostimulatory spherical nucleic acid (SNA) modified with type B CpG oligonucleotides designed to agonize TLR9 and elicit immune responses useful in oncology applications.

HY-157693

C18:1 Cyclic LPA		Phospholipids
C18:1 Cyclic LPA is a naturally occurring analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA), characterized by the formation of a 5-membered ring between its sn-2 hydroxy group and the sn-3 phosphate. This unique structure allows C18:1 Cyclic LPA to influence a variety of cellular functions, such as inhibiting cell cycle progression, promoting the formation of stress fibers, curtailing tumor cell invasiveness and metastasis, and modulating the differentiation and survival of neuronal cells. Notably, many of these cellular effects elicited by C18:1 Cyclic LPA appear to counter those induced by LPA, despite the activation of seemingly similar receptor populations.

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