Search Result

Results for "

gram-negative bacterial

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (170) ADC Linker (1) Antibiotic (104) Apoptosis (2) Aurora Kinase (6) Autophagy (2) Bcl-2 Family (3) Beta-lactamase (4) DNA/RNA Synthesis (17) Drug Metabolite (2) Endogenous Metabolite (2) Fluorescent Dye (1) Fungal (6) GSK-3 (6) Isotope-Labeled Compounds (13) NF-κB (1) Nucleoside Antimetabolite/Analog (2) Parasite (10) PD-1/PD-L1 (1) PDI (1) Penicillin-binding protein (PBP) (10) Platelet-activating Factor Receptor (PAFR) (1) PROTAC Linkers (1) Reactive Oxygen Species (1) Topoisomerase (8)
By Research Areas:	Cancer (24) Cardiovascular Disease (1) Infection (173) Inflammation/Immunology (14) Metabolic Disease (2)
Click Chemistry:	ADC Synthesis (1) PROTAC Synthesis (1) Alkynes (1)

179

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Targets Recommended: Bacterial

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-A0253

Cefacetrile Cephacetrile; Cephacetril	Bacterial Antibiotic	Infection
Cefacetrile (Cephacetrile) is a broad-spectrum antibiotic that is effective in gram-positive and gram-negative bacterial infection .

HY-B1466

Mezlocillin sodium BAY-f 1353 sodium	Bacterial Antibiotic	Infection
Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research .

HY-B1118

Secnidazole RP-14539; PM-185184	Parasite Antibiotic Bacterial	Infection
Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .

HY-158682

LpxC-IN-13	Bacterial	Infection
LpxC-IN-13 (Compound 13) is a LpxC inhibitor, with an IC₅₀ 18.06 nM. LpxC-IN-13 effectively inhibits Gram-negative bacterial infection .

HY-142127

Ribostamycin Vistamycin; SF-733	Bacterial Antibiotic PDI	Infection
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI .

HY-A0253R

Cefacetrile (Standard)	Bacterial Antibiotic	Infection
Cefacetrile (Standard) is the analytical standard of Cefacetrile. This product is intended for research and analytical applications. Cefacetrile (Cephacetrile) is a broad-spectrum antibiotic that is effective in gram-positive and gram-negative bacterial infection .

HY-B1466A

Mezlocillin BAY-f 1353	Antibiotic Bacterial	Infection
Mezlocillin (BAY-f 1353) is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin is active against both gram-negative and gram-positive bacteria. Mezlocillin can be used in bacterial infection research .

HY-N7139

Penicillin G Benzylpenicillin	Antibiotic Bacterial	Infection
Penicillin G is a potent penicillinantibiotic. Penicillin G can be used for bacterial infection. Penicillin G has potent activity against all Gram-positive bacteria and Gram-negative cocci .

HY-161689

Antibacterial agent 220	Bacterial	Infection
Antibacterial agent 220 is a potent antibacterial agent that can directly destroy bacterial cell membranes. Antibacterial agent 220 effectively combats Gram-positive and and Gram-negative pathogens, including drug-resistant strains .

HY-B1466R

Mezlocillin sodium (Standard) BAY-f 1353 sodium (Standard)	Bacterial Antibiotic	Infection
Mezlocillin (sodium) (Standard) is the analytical standard of Mezlocillin (sodium). This product is intended for research and analytical applications. Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research[1][2].

HY-B1118A

Secnidazole hemihydrate RP-14539 hemihydrate; PM-185184 hemihydrate	Antibiotic Bacterial Parasite	Infection
Secnidazole (RP-14539) hemihydrate is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole hemihydrate, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole hemihydrate has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole hemihydrate can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .

HY-U00380

Tigemonam	Bacterial Antibiotic	Infection
Tigemonam is a monobactam, with potent activity against Gram-negative aerobic bacterial pathogens.

HY-B1828

Spectinomycin	Antibiotic Bacterial	Infection
Spectinomycin is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin acts by selectively targeting to the *bacterial* ribosome and interrupting protein synthesis. Spectinomycin is also a noncompetitive inhibitor of td intron RNA .

HY-B0438

Spectinomycin dihydrochloride 3 Publications Verification	Bacterial Antibiotic	Infection
Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the *bacterial* ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an K_i value of 7.2 mM ^- .

HY-B1118R

Secnidazole (Standard)	Parasite Antibiotic Bacterial	Infection
Secnidazole (Standard) is the analytical standard of Secnidazole. This product is intended for research and analytical applications. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis .

HY-B1828A

Spectinomycin dihydrochloride pentahydrate 3 Publications Verification Spectinomycin hydrochloride hydrate	Bacterial Antibiotic	Infection
Spectinomycin dihydrochloride pentahydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride pentahydrate acts by selectively targeting to the *bacterial* ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride pentahydrate is also a noncompetitive inhibitor of td intron RNA with an K_i value of 7.2 mM ^- .

HY-W928617

Spectinomycin sulfate hydrate	Antibiotic Bacterial	Infection
Spectinomycin sulfate hydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin sulfate hydrate acts by selectively targeting to the *bacterial* ribosome and interrupting protein synthesis. Spectinomycin sulfate hydrate is also a noncompetitive inhibitor of td intron RNA with an K_i value of 7.2 mM ^- .

HY-130379

Propargyl-PEG8-acid	ADC Linker PROTAC Linkers Bacterial	Infection Cancer
Propargyl-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria . Propargyl-PEG8-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B1190

Cefadroxil 1 Publications Verification BL-S 578	Bacterial Antibiotic	Infection
Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.

HY-143415

Metallo-β-lactamase-IN-7	Beta-lactamase Bacterial	Infection
Metallo-β-lactamase-IN-7 is a potent VIM-Type metallo-β-lactamase inhibitor with IC₅₀s of 0.019 μM, 13.64 μM, 0.38 μM for VIM-2, VIM-1 and VIM-5. Metallo-β-lactamase-IN-7 potentiate antibacterial activity of Meropenem against the Gram-negative bacterial strains .

HY-Q50147

Antimicrobial agent-21	Bacterial	Infection
Antimicrobial agent-21 (Compound IIm) is a *bacterial* inhibitor. Antimicrobial agent-21 is active against gram-positive and gram-negative bacterial .

HY-161364

Antibacterial agent 200	Bacterial	Inflammation/Immunology
Antibacterial agent 200 (pyridyl HH 7), a unique hydrazyl hydroxycoumarin (HH), has strong antibacterial efficacy and broad antibacterial spectrum with MIC values ranging from 0.5 to 32 μg/mL for Gram-positive and Gram-negative bacteria. Antibacterial agent 200 exhibits a good inhibition against Pseudomonas aeruginosa 27853 with a low MIC value of 0.5 μg/mL. Antibacterial agent 200 can eradicate the integrity of bacterial membrane, result in the leakage of intracellular proteins, and interact with bacterial DNA gyrase via non-covalent binding .

HY-118797

Malioxamycin	Antibiotic Bacterial	Infection
Malioxamycin is an antibiotic that inhibits Gram-negative bacteria by inhibiting peptidoglycan synthesis in bacterial cell walls and promoting the formation of spheroplasts .

HY-122071

Bicyclomycin	Antibiotic Bacterial	Infection
Bicyclomycin is an antibiotic. Bicyclomycin has *anti-Bacterial* activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa .

HY-B0438R

Spectinomycin dihydrochloride (Standard)	Bacterial Antibiotic	Infection
Spectinomycin (dihydrochloride) (Standard) is the analytical standard of Spectinomycin (dihydrochloride). This product is intended for research and analytical applications. Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM[1]-[5].

HY-B1174

Bekanamycin Kanamycin B	Antibiotic Bacterial	Infection
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .

HY-14456A

MAC13243 1 Publications Verification	Bacterial	Infection
MAC13243, an antibacterial agent, is an inhibitor of bacterial lipoprotein targeting chaperone, LolA. MAC13243 is an antibacterial agent with Gram-negative selectivity .

HY-149309

Topoisomerase inhibitor 2	Topoisomerase	Infection
Topoisomerase inhibitor 2 (18C) is a bacterial topoisomeraseinhibitor that exhibits potent broad-spectrum activity against multidrug-resistant Gram-negative bacteria .

HY-P10546

Polyalanine peptide pALA	Bacterial	Infection
Polyalanine peptide (pALA) is an antimicrobial peptide that targets biofilms and Gram-negative bacteria and is non-toxic to mammalian cells. Polyalanine peptide forms an α-helical conformation that effectively permeabilizes Gram-negative bacterial membranes, thereby inducing lethal cell leakage. Polyalanine peptide can be used in anti-infection research .

HY-14865

Omadacycline Maximum Cited Publications 23 Publications Verification PTK 0796; Amadacycline	Bacterial Antibiotic	Infection
Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .

HY-14865B

Omadacycline tosylate Maximum Cited Publications 23 Publications Verification PTK 0796 tosylate; Amadacycline tosylate	Bacterial Antibiotic	Infection
Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .

HY-14865C

Omadacycline hydrochloride Maximum Cited Publications 23 Publications Verification PTK0796 hydrochloride; Amadacycline hydrochloride	Bacterial Antibiotic	Infection
Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .

HY-14865A

Omadacycline mesylate PTK 0796 mesylate; Amadacycline mesylate	Bacterial Antibiotic	Infection
Omadacycline (PTK 0796) mesylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline mesylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline mesylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline mesylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .

HY-B1190S

Cefadroxil-d4 hydrate BL-S 578-d₄ hydrate	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Cefadroxil-d₄ (hydrate) is the deuterium labeled Cefadroxil. Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.

HY-B1282A

Sulfaquinoxaline sodium salt	Bacterial Parasite Antibiotic	Infection
Sulfaquinoxaline sodium salt is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections .

HY-B1282

Sulfaquinoxaline	Bacterial Parasite Antibiotic	Infection
Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections .

HY-30219

D-(+)-Phenyllactic acid D-3-Phenyllactic acid	Bacterial Endogenous Metabolite Bcl-2 Family	Infection
D-(+)-Phenyllactic acid is an *anti-bacterial* agent, excreted by Geotrichum candidum, inhibits a range of Gram-positive from humans and foodstuffs and Gram-negative bacteria found in humans .

HY-19581

Baquiloprim	Antibiotic Bacterial	Infection
Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria .

HY-106257A

Ceftolozane TFA 1 Publications Verification	Antibiotic Bacterial	Infection
Ceftolozane TFA is a cephalosporin antibiotic that can be used to inhibit Gram-negative bacterial infections. Ceftolozane TFA can be used to synthesize new antibiotic that are more potent and safer .

HY-P5555

LMW peptide	Bacterial	Infection
LMW peptide is an antimicrobial peptide. LMW peptide is active against Gram-positive and Gram-negative bacterial, such as B. subtilis, L. monocytogenes, E. coli, P. aeruginosa, V. cholera .

HY-12888

AZD5099	Topoisomerase Bacterial	Infection
AZD5099, an antibacterial agent, is a potent and selective bacterial topoisomerase II inhibitor. AZD5099 potently inhibits the infections caused by *Gram-positive* and fastidious **Gram-negative bacteria** .

HY-17628

Cefiderocol 10+ Cited Publications S-649266	Bacterial Antibiotic	Infection
Cefiderocol (S-649266) is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative *bacterial* species with MIC₅₀s of 2 μg/mL or less.

HY-B1596A

Ceftizoxime sodium 1 Publications Verification SKF-88373	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Ceftizoxime sodium (SKF-88373) is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.

HY-139798

Iboxamycin	Bacterial	Infection
Iboxamycin is a potent antibiotic candidate bearing a fused bicyclic amino acid residue. Iboxamycin is orally bioavailable, safe and effective in researching both Gram-positive and Gram-negative bacterial infections in mice .

HY-14865R

Omadacycline (Standard)	Bacterial Antibiotic	Infection
Omadacycline (Standard) is the analytical standard of Omadacycline. This product is intended for research and analytical applications. Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .

HY-14865CR

Omadacycline hydrochloride (Standard) PTK0796 hydrochloride (Standard); Amadacycline hydrochloride (Standard)	Bacterial Antibiotic	Infection
Omadacycline (hydrochloride) (Standard) is the analytical standard of Omadacycline (hydrochloride). This product is intended for research and analytical applications. Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections[1][2][3][4].

HY-14865BR

Omadacycline (tosylate) (Standard)	Bacterial Antibiotic	Infection
Omadacycline (tosylate) (Standard) is the analytical standard of Omadacycline (tosylate). This product is intended for research and analytical applications. Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .

HY-W748000

Kocurin PM181104; Baringolin	Antibiotic Bacterial	Infection
Kocurin (PM181104) is a thiazolyl cyclic-peptide antibiotic. Kocurin inhibits bacterial growth by impeding bacterial protein biosynthesis during the translation phase. Kocurin has strong inhibitory activity against Gram-positive bacteria, but no activity against fungi and Gram-negative bacteria .

HY-P10519

Brevicidine	Bacterial	Infection
Brevicidine is a non-ribosomally synthesized antimicrobial peptide with potent antibacterial activity against Gram-negative pathogens. Brevicidine disrupts the morphology of bacteria by binding to polysaccharides (LPS) on bacterial cell membranes to form holes .

HY-118036

ACT-387042	Topoisomerase	Infection
ACT-387042 is a bacterial topoisomerase inhibitor with broad-spectrum activity against Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus and penicillin- and fluoroquinolone-resistant Streptococcus pneumoniae .

Cat. No.	Product Name	Type

HY-D0128

4-Methylherniarin 7-Methoxy-4-methylcoumarin	Fluorescent Dyes/Probes
4-Methylherniarin (7-Methoxy-4-methylcoumarin) is a coumarin derivative and fluorescent label, has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC₅₀ values of 11.76 μg/ml and 13.47 μg/ml .

Cat. No.	Product Name	Type

HY-W016473

Adamantane-carboxylic acid

Biochemical Assay Reagents

Adamantane-carboxylic acid is a compound with inhibitory activity against microorganisms. Although its specific target has not been clearly defined, it can inhibit Gram-positive bacteria and some Gram-negative bacteria. It forms a 1-monoacylglycerol derivative through a direct reaction with glycidol, and exerts its antibacterial effect by mechanisms such as altering the permeability of the bacterial cell membrane. This compound can be used in the research of antibacterial agents in the food and cosmetic industries to reduce harmful microbial flora and extend the shelf life of products .

HY-W354851

Pisiferic acid	Biochemical Assay Reagents
Pisiferic acid is an antibacterial agent with inhibitory activity against Gram-negative/positive bacteria such as P. vulgaris, S. aureus and B. subtilis. Pisiferic acid can be used to study bacterial infections .

Cat. No.	Product Name	Target	Research Area

HY-A0248A

Polymyxin B1 1 Publications Verification	Bacterial	Infection
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant **Gram-negative bacterial** infections treatment .

HY-P3328A

MDP1 acetate	Bacterial	Infection
MDP1 acetate, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 acetate has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .

HY-P10546

Polyalanine peptide pALA	Bacterial	Infection
Polyalanine peptide (pALA) is an antimicrobial peptide that targets biofilms and Gram-negative bacteria and is non-toxic to mammalian cells. Polyalanine peptide forms an α-helical conformation that effectively permeabilizes Gram-negative bacterial membranes, thereby inducing lethal cell leakage. Polyalanine peptide can be used in anti-infection research .

HY-P5555

LMW peptide	Bacterial	Infection
LMW peptide is an antimicrobial peptide. LMW peptide is active against Gram-positive and Gram-negative bacterial, such as B. subtilis, L. monocytogenes, E. coli, P. aeruginosa, V. cholera .

HY-W748000

Kocurin PM181104; Baringolin	Antibiotic Bacterial	Infection
Kocurin (PM181104) is a thiazolyl cyclic-peptide antibiotic. Kocurin inhibits bacterial growth by impeding bacterial protein biosynthesis during the translation phase. Kocurin has strong inhibitory activity against Gram-positive bacteria, but no activity against fungi and Gram-negative bacteria .

HY-P10519

Brevicidine	Bacterial	Infection
Brevicidine is a non-ribosomally synthesized antimicrobial peptide with potent antibacterial activity against Gram-negative pathogens. Brevicidine disrupts the morphology of bacteria by binding to polysaccharides (LPS) on bacterial cell membranes to form holes .

HY-P3328

MDP1	Bacterial	Infection
MDP1, a Melittin-derived peptide, alters the integrity of both Gram-positive and Gram-negative bacterial membranes and kills the bacteria via membrane damages. MDP1 has a high-antibacterial activity against multidrug resistant (MDR) and reference strains of S. aureus, E. coli, and P. aeruginosa .

HY-N14166

Empedopeptin	Bacterial	Infection
Empedopeptin has anti-Gram-negative bacterial activity .

HY-P2458

CAP18 (rabbit)	Bacterial	Infection
CAP18 (rabbit) is a 37 amino acids antimicrobial peptide originally isolated from rabbit granulocytes. CAP18 (rabbit) has broad antimicrobial activity against both *Gram-positive* (IC₅₀, 130-200 nM) and *Gram-negative* (IC₅₀, 20-100 nM) *bacteria. CAP18 (rabbit) has the potential for bacterial* sepsis research .

HY-P5724

Nv-CATH	Bacterial	Infection
Nv-CATH is an antibacterial peptide of frog origin. Nv-CATH has broad-spectrum antibacterial activity against gram-positive and gram-negative bacteria. Nv-CATH significantly protects mice from fatal infections caused by Staphylococcus aureus. Nv-CATH protects mice from bacterial infection through antimicrobial immunoregulatory duality .

HY-A0248B

Polymyxin B2	Antibiotic Bacterial	Infection
Polymyxin B2 is a polypeptide antibiotic that has antibacterial activity, particularly against gram-negative bacteria. Polymyxin B2 kills the bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting the integrity of the cell membrane and causing the cell contents to leak. Polymyxin B2 can be used in antibiotic development and treatment of drug-resistant strains .

HY-P0270

Magainin 2 Magainin II	Bacterial Antibiotic Fungal	Infection
Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .

HY-P10913

HYNIC-UBI29-41	Bacterial	Infection
HYNIC-UBI29-41 is composed of a bifunctional chelator HYNIC and an antimicrobial peptide UBI 29-41. HYNIC-UBI29-41 retains the antibacterial properties of UBI 29-41, and exhibits good affinity to Gram-positive and Gram-negative bacteria. HYNIC-UBI29-41 can be used as an imaging agent for bacterial infection detection in mouse models, when labeled with the radioactive element technetium (99mTc) .

HY-105048A

Omiganan pentahydrochloride	Bacterial	Infection
Omiganan pentahydrochloride is a cationic peptide compound with a broad antibacterial profile. Omiganan pentahydrochloride is capable of inhibiting a variety of bacteria, including yeast, and is active against both gram-positive and gram-negative bacteria. Omiganan pentahydrochloride is able to interact with the bacterial cell membrane, causing the destruction of the cell membrane and the death of the bacteria. Omiganan pentahydrochloride can be used for the study of antimicrobial activity against pathogens commonly associated with catheter-associated infections, including strains with drug-resistant phenotypes .

HY-P5601

Thanatin	Bacterial Fungal	Infection
Thanatin is an inducible cationic antimicrobial peptide. Thanatin is a pathogen-inducible single-disulfide-bond-containing β-hairpin AMP. Thanatin displays broad-spectrum activity against both Gram-negative and Gram-positive bacteria as well as against various species of fungi with MICs of 0.3-40 µM, 0.6-40 µM and 0.6-20 µM, respectively. Thanatin has the property of competitive replacement of divalent cations from bacterial outer membrane (OM), leading to OM disruption .

HY-P5601A

Thanatin TFA	Bacterial Fungal	Infection
Thanatin TFA is an inducible cationic antimicrobial peptide. Thanatin TFA s a pathogen-inducible single-disulfide-bond-containing β-hairpin AMP. Thanatin TFA displays broad-spectrum activity against both Gram-negative and Gram-positive bacteria as well as against various species of fungi with MICs of 0.3-40 µM, 0.6-40 µM and 0.6-20 µM, respectively. Thanatin TFA has the property of competitive replacement of divalent cations from bacterial outer membrane (OM), leading to OM disruption .

Cat. No.	Product Name

HY-K1044

Polymyxin B (1,000×), Sterile

Polymixin B is a mixture of B1 and B2 polypeptides obtained from different strains of Bacillus polymyxa, with antibacterial activity against gram-negative bacteria. It can bind lipopolysaccharide (LPS) of the outer membrane of gram-negative bacteria and disrupts the cytoplasmic membrane by inducing large pores to allow nucleotide leakage in bacterial walls. This disrupts the permeability of the cytoplasmic membrane.

HY-K1006

Penicillin-Streptomycin (100×), Sterile 35+ Cited Publications
MCE MCE Penicillin-Streptomycin (100×), Sterile is used to prevent bacterial contamination of cell culture due to their effective combined action against gram-positive and gram-negative bacteria.

HY-K1010

Penicillin-Streptomycin-Glutamine (100×), Sterile
MCE Penicillin-Streptomycin-Glutamine (100×), sterile is used to prevent bacterial contamination of cell culture due to their effective combined action against gram-positive and gram-negative bacteria.

HY-K1050

Gentamicin, Sterile 1 Publications Verification
MCE Gentamicin, Sterile acts by binding to the 30S subunit of the bacterial ribosome leading to inhibition of protein synthesis and death in susceptible bacteria, mainly for gram-negative and gram-positive bacteria.

HY-K0014

Penicillin-Streptomycin-Neomycin (PSN) (100×), Sterile
MCE Penicillin-Streptomycin-Neomycin (PSN) (100×), Sterile is used to prevent bacterial contamination of cell culture due to their effective combined action against gram-positive and gram-negative bacteria.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0438

Spectinomycin dihydrochloride 3 Publications Verification	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Resistance Selection Source classification Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic
Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the *bacterial* ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an K_i value of 7.2 mM ^- .

HY-B1174

Bekanamycin Kanamycin B	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic Bacterial
Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .

HY-30219

D-(+)-Phenyllactic acid D-3-Phenyllactic acid	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Bacterial Endogenous Metabolite Bcl-2 Family
D-(+)-Phenyllactic acid is an *anti-bacterial* agent, excreted by Geotrichum candidum, inhibits a range of Gram-positive from humans and foodstuffs and Gram-negative bacteria found in humans .

HY-142127

Ribostamycin Vistamycin; SF-733	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic PDI
Ribostamycin (Vistamycin) is a broad-spectrum aminoglycoside antibiotic. Ribostamycin is effective against Gram-Negative and Gram-Positive bacterial infection. Ribostamycin also inhibits the chaperone activity of PDI .

HY-B1828

Spectinomycin	Microorganisms Source classification	Antibiotic Bacterial
Spectinomycin is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin acts by selectively targeting to the *bacterial* ribosome and interrupting protein synthesis. Spectinomycin is also a noncompetitive inhibitor of td intron RNA .

HY-118797

Malioxamycin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Malioxamycin is an antibiotic that inhibits Gram-negative bacteria by inhibiting peptidoglycan synthesis in bacterial cell walls and promoting the formation of spheroplasts .

HY-122071

Bicyclomycin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Bicyclomycin is an antibiotic. Bicyclomycin has *anti-Bacterial* activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa .

HY-B0438R

Spectinomycin dihydrochloride (Standard)	Structural Classification Microorganisms Antibiotics Resistance Selection Source classification Mammalian Cell Culture Antibacterial Disease Research Other Antibiotics	Bacterial Antibiotic
Spectinomycin (dihydrochloride) (Standard) is the analytical standard of Spectinomycin (dihydrochloride). This product is intended for research and analytical applications. Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an Ki value of 7.2 mM[1]-[5].

HY-W748000

Kocurin PM181104; Baringolin	Microorganisms Source classification	Antibiotic Bacterial
Kocurin (PM181104) is a thiazolyl cyclic-peptide antibiotic. Kocurin inhibits bacterial growth by impeding bacterial protein biosynthesis during the translation phase. Kocurin has strong inhibitory activity against Gram-positive bacteria, but no activity against fungi and Gram-negative bacteria .

HY-B1174R

Bekanamycin (Standard)	Structural Classification Microorganisms Antibiotics Source classification Antibacterial Disease Research Other Antibiotics	Antibiotic Bacterial
Bekanamycin (Standard) is the analytical standard of Bekanamycin. This product is intended for research and analytical applications. Bekanamycin (Kanamycin B) is an aminoglycoside antibiotic produced by Streptomyces kanamyceticus, against an array of Gram-positive and Gram-negative bacterial strain .

HY-125650

Pseudouridimycin 1 Publications Verification PUM	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Antibiotic DNA/RNA Synthesis Bacterial Nucleoside Antimetabolite/Analog
Pseudouridimycin (PUM) is an antibiotic that selectively inhibits bacterial RNA polymerase (RNAP), with an IC₅₀ of about 0.1 μM and MICs of 4-6 μg/mL. Pseudouridimycin is a C-nucleoside analogue that's effective against both Gram-negative and Gram-positive bacteria. Pseudouridimycin inhibits bacterial growth in vitro and shows activity in a mouse model of purulent streptococcal peritonitis .

HY-30219R

D-(+)-Phenyllactic acid (Standard) D-3-Phenyllactic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Bacterial Endogenous Metabolite Bcl-2 Family
D-(+)-Phenyllactic acid (Standard) is the analytical standard of D-(+)-Phenyllactic acid. This product is intended for research and analytical applications. D-(+)-Phenyllactic acid is an anti-bacterial agent, excreted by Geotrichum candidum, inhibits a range of Gram-positive from humans and foodstuffs and Gram-negative bacteria found in humans[1].

HY-N7224

N-Formylfortimicin A SF-1854	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Bacterial Antibiotic
N-Formylfortimicin A (SF-1854) is an aminoglycoside antibiotic with broad-spectrum antibacterial activity. It primarily acts on bacterial ribosomes to inhibit protein synthesis and exhibits notable inhibitory effects against various Gram-positive and Gram-negative bacteria (e.g., E. coli with a MIC of 12.5-50 μg/mL), making it a potential candidate for research on bacterial infection-related diseases .

HY-A0248A

Polymyxin B1 1 Publications Verification	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant **Gram-negative bacterial** infections treatment .

HY-N14166

Empedopeptin	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Bacterial
Empedopeptin has anti-Gram-negative bacterial activity .

HY-N14260

Hypelcin A-II	Structural Classification Natural Products Microorganisms Source classification	Bacterial Fungal
Hypelcin A-II has anti-Gram-negative bacterial and fungal activity .

HY-N14266

Hypelcin A-IV	Structural Classification Microorganisms Antibiotics Source classification	Bacterial Fungal
Hypelcin A-IV has anti-Gram-negative bacterial and fungal activity .

HY-N14254

Hypelcin A-Ⅰ	Structural Classification Natural Products Microorganisms Source classification	Bacterial Fungal
Hypelcin A-I has anti-Gram-negative bacterial and fungal activity .

HY-N5175

Cephaibol A	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial Parasite
Cephaibol A has anti-Gram-positive bacterial activity, but no anti-Gram-negative bacterial activity. Cephaibol A also has the effect of deworming and anti-ectoparasite .

HY-N14612

Griseochelin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial
Griseochelin has anti-Gram-negative bacterial activity, and has inhibitory effect on coccidioides .

HY-N5176

Cephaibol B	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial Parasite
Cephaibol B has anti-Gram-positive bacterial activity, but no anti-Gram-negative bacterial activity. Cephaibol B also has the effect of deworming and anti-ectoparasite .

HY-P0270

Magainin 2 Magainin II	Infection Structural Classification Natural Products Animals Classification of Application Fields Source classification Disease Research Fields	Bacterial Antibiotic Fungal
Magainin 2 (Magainin II) is an antimicrobial peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .

HY-W013549

6-Aminopenicillanic acid 6-APA	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Drug Metabolite Bacterial
6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses .

HY-N8497

Leoidin	Structural Classification Monophenols Microorganisms Source classification Phenols	Bacterial
Leoidin is an OATP1B1 and OATP1B3 inhibitor with K_i values of 0.08 and 1.84 μM，respectively. Leoidin inhibits sodium fluorescein uptake in CHO cells expressing the human OATP1B1 and OATP1B3. Leoidin is an antibacterial agent against both Gram-positive and Gram-negative pathogens. Leoidin inhibits phenylalanyl-tRNA synthetase (PheRS) (IC₅₀= 42 μM) and inhibits protein synthesis in bacterial. Leoidin can be isolated from L. gangaleoides .

HY-W013549R

6-Aminopenicillanic acid (Standard)	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Drug Metabolite Bacterial
6-Aminopenicillanic acid (Standard) is the analytical standard of 6-Aminopenicillanic acid. This product is intended for research and analytical applications. 6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses .

HY-121120

Isosulfazecin	Structural Classification Microorganisms Antibiotics Source classification Beta-lactam Antibiotics	Antibiotic
Isosulfazecin (iSZ) is a novel β-lactam antibiotic produced by Pseudomonas acidophilus sp., synthesized in a nutrient solution supplemented with glycerol and sodium thiosulfate under aerobic conditions in parallel with bacterial growth. It is purified by chromatography and crystallization from aqueous methanol. Physicochemical analysis determined its molecular formula to be C12H20N4O9S, showing a structure with a β-lactam ring, methoxyl and sulfonate groups. Acid hydrolysis yields L-alanine and D-glutamic acid. iSZ is a diastereomer of sulfadiazine and exhibits moderate activity against both gram-positive and gram-negative bacteria, but potent activity against bacteria resistant to β-lactam antibiotics .

HY-N1416

Pogostone 2 Publications Verification	Structural Classification Natural Products Entada phaseoloides (L.) Merr. Classification of Application Fields Labiatae Source classification Plants Inflammation/Immunology Disease Research Fields	Bacterial Apoptosis Autophagy
Pogostone is isolated from patchouli oil with anti-bacterial and anti-cancer activities. Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 µg/ml . Pogostone induces cell apoptosis and autophagy .

HY-N1416R

Pogostone (Standard)	Structural Classification Natural Products Entada phaseoloides (L.) Merr. Labiatae Source classification Plants	Bacterial Apoptosis Autophagy
Pogostone (Standard) is the analytical standard of Pogostone. This product is intended for research and analytical applications. Pogostone is isolated from patchouli oil?with anti-bacterial and anti-cancer activities.?Pogostone inhibits both gram negative and gram positive bacteria, also show inhibitory effect on corynebacterium xerosis with a MIC value of 0.098 μg/ml .?Pogostone induces cell apoptosis and autophagy .

Cat. No.	Product Name	Chemical Structure

HY-W011117S1

Danofloxacin-d3-1
Danofloxacin-d3-1 is deuterium labeled Danofloxacin. Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria, mycoplasma and chlamydia species, and plays an antimicrobial role by inhibition of bacterial DNA-gyrase .

HY-W653936

Cephalexin-d5 hydrate

Cephalexin-d₅ (hydrate) is deuterium labeled Cephalexin (monohydrate). Cephalexin (Cefalexin) monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al .

HY-B1190S

Cefadroxil-d4 hydrate
Cefadroxil-d₄ (hydrate) is the deuterium labeled Cefadroxil. Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections.

HY-19581S

Baquiloprim-d6
Baquiloprim-d₆ is deuterium labeled Baquiloprim. Baquiloprim, an antibiotic, is a selective inhibitor of bacterial dihydrofolate reductases. Baquiloprim possesses in vitro bacteriostatic activity against both Gram-negative and Gram-positive bacteria[1][2].

HY-B1282S

Sulfaquinoxaline-d4
Sulfaquinoxaline-d₄ is the deuterium labeled Sulfaquinoxaline. Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections[1][2].

HY-106257S

Ceftolozane-d6 TFA
Ceftolozane-d₆ TFA is a deuterated labeled Ceftolozane TFA (HY-106257A). Ceftolozane TFA is a cephalosporin antibiotic that can be used to inhibit Gram-negative bacterial infections. Ceftolozane TFA can be used to synthesize new antibiotic that are more potent and safer .

HY-B1085S

Cinoxacin-d5

Cinoxacin-d₅ is the deuterium-labeled Cinoxacin (HY-B1085) . Cinoxacin (Compound 64716)，a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis .

HY-17628S1

Cefiderocol-d6
Cefiderocol-d₆ (S-649266-d₆) is a deuterated labeled Cefiderocol (HY-17628). Cefiderocol is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less .

HY-W011117S

Danofloxacin-d3
Danofloxacin-d₃ is deuterium labeled Danofloxacin. Danofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent. Danofloxacin shows a broad spectrum of activity against most Gram-negative and Gram-positive bacteria, mycoplasma and chlamydia species, and plays an antimicrobial role by inhibition of bacterial DNA-gyrase[1][2].

HY-B0330DS

(R)-Ofloxacin-d3

(R)-Ofloxacin-d₃ is the deuterium labeled (R)-Ofloxacin. (R)-Ofloxacin is the dextrorotatory enantiomer of Ofloxacin (HY-B0125) and is an orally effective fluoroquinolone antibiotic. (R)-Ofloxacin can inhibit the activity of bacterial DNA topoisomerase II, interfere with bacterial DNA replication and repair, and exert a bactericidal effect. (R)-Ofloxacin has a broad-spectrum antibacterial activity and has inhibitory effects on both Gram-negative and Gram-positive bacteria .

HY-B1118S2

Secnidazole-d4

Secnidazole-d₄ is the deuterium labeled Secnidazole[1]. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis[1][2][3].

HY-B0136S

Cefdinir-13C,15N2

Cefdinir- ¹³C, ¹⁵N₂ (FK-482- ¹³C, ¹⁵N₂) is ¹³C and ¹⁵N labeled Cefdinir. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .

HY-B0200BS

Cephalexin-d5 monohydrate

Cephalexin-d₅ (monohydrate) is the deuterium labeled Cephalexin monohydrate. Cephalexin monohydrate is a potent, orally active and the first-generation cephalosporin antibiotic. Cephalexin monohydrate kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1].

HY-B0200S

Cephalexin-d5

Cephalexin-d₅ is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation cephalosporin antibiotic. Cephalexin kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1].

HY-B0712S1

Ceftriaxone-13C2,d3 triethylammonium salt

Ceftriaxone- ¹³C₂,d₃ triethylammonium salt is ¹³C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC₅₀ value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .

Cat. No.	Product Name		Classification

HY-130379

Propargyl-PEG8-acid		ADC Synthesis Alkynes PROTAC Synthesis
Propargyl-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria . Propargyl-PEG8-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

gram-negative bacterial

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Natural
Products