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Results for "

measure

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (1) Acyltransferase (1) Amylases (1) Bacterial (2) Biochemical Assay Reagents (31) Calcium Channel (2) Casein Kinase (1) Caspase (4) Complement System (1) DNA Stain (2) Drug Metabolite (1) Endogenous Metabolite (19) Epoxide Hydrolase (1) FAAH (2) Fluorescent Dye (49) Glucosidase (1) GSK-3 (1) HIV Protease (1) Huntingtin (1) Isotope-Labeled Compounds (1) Lipase (1) mAChR (4) nAChR (2) p38 MAPK (1) Parasite (1) PKA (1) Prolyl Endopeptidase (PREP) (1) Proteasome (2) Reactive Oxygen Species (1) Ribosomal S6 Kinase (RSK) (1) SARS-CoV (1) Ser/Thr Protease (3)
By Research Areas:	Cancer (11) Cardiovascular Disease (5) Endocrinology (1) Infection (6) Inflammation/Immunology (7) Metabolic Disease (22) Neurological Disease (6)

By Targets:

11β-HSD (1)

Acyltransferase (1)

Amylases (1)

Bacterial (2)

Biochemical Assay Reagents (31)

Calcium Channel (2)

Casein Kinase (1)

Caspase (4)

Complement System (1)

DNA Stain (2)

Drug Metabolite (1)

Endogenous Metabolite (19)

Epoxide Hydrolase (1)

FAAH (2)

Fluorescent Dye (49)

Glucosidase (1)

GSK-3 (1)

HIV Protease (1)

Huntingtin (1)

Isotope-Labeled Compounds (1)

Lipase (1)

mAChR (4)

nAChR (2)

p38 MAPK (1)

Parasite (1)

PKA (1)

Prolyl Endopeptidase (PREP) (1)

Proteasome (2)

Reactive Oxygen Species (1)

Ribosomal S6 Kinase (RSK) (1)

SARS-CoV (1)

Ser/Thr Protease (3)

By Research Areas:

Cancer (11)

Cardiovascular Disease (5)

Endocrinology (1)

Infection (6)

Inflammation/Immunology (7)

Metabolic Disease (22)

Neurological Disease (6)

150

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-107850

Pregnanediol NSC 1612; NSC 47462	Endogenous Metabolite	Metabolic Disease
Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo .

HY-D0936

SPQ	Fluorescent Dye	Others
SPQ is being used to examine and measure membrane chloride transport mechanisms.

HY-101886

5-BrUTP sodium salt 5-Bromouridine 5'-triphosphate sodium salt	Biochemical Assay Reagents	Others
5-BrUTP sodium salt can be used to label RNA to measure the transcription.

HY-137220

Z-Gly-Pro-pNA	Prolyl Endopeptidase (PREP)	Others
Z-Gly-Pro-pNA is a substrate for measuring prolyl endopeptidase (PEP) inhibitory activity .

HY-D0789

ANTS	Fluorescent Dye	Others
ANTS is a fluorescent dye. ANTS and DPX are encapsulated in liposomes can be an effective approach for measuring membrane leakage .

HY-130210

Oxonol V	Fluorescent Dye	Others
Oxonol V is a slow-response sensitive probe for measuring cellular membrane potential.

HY-D1750

Rhodamine B thiolactone	Fluorescent Dye	Others
Rhodamine B thiolactone is a high-sensitive Hg ²⁺ indicator used for measuring Hg ²⁺ concentration.

HY-W129633

2,6-Dichlorophenolindophenol sodium hydrate DCIP sodium hydrate; DPIP sodium hydrate	Biochemical Assay Reagents	Others
2,6-Dichlorophenolindophenol (sodium hydrate) is a blue reduction dye used as an indicator for measuring the content of vitamin C.

HY-N7259B

(±)-Isomenthone	Others	Others
(±)-Isomenthone is a naturally active compound, a racemate of Isomenthone. (±)-Isomenthone has optical activity and is mainly used to measure the activity .

HY-P3920

Cys-Kemptide	PKA	Cancer
Cys-Kemptide is a cysteine-terminated substrate peptide that can used to measure protein kinase A (PKA) activity .

HY-P4326

Boc-Val-Pro-Arg-AMC	Fluorescent Dye	Others
Boc-Val-Pro-Arg-MCA is a sensitive fluorogenic substrate for measuring trypsin-like serine proteases activity .

HY-111391

Resazurin sodium 3 Publications Verification Diazoresorcinol sodium	Bacterial	Others
Resazurin sodium (Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.

HY-137784

Boc-Val-Pro-Arg-AMC hydrochloride	Fluorescent Dye	Others
Boc-Val-Pro-Arg-AMC hydrochloride is a sensitive fluorogenic substrate for measuring trypsin-like serine proteases activity .

HY-P10236

Ac-WEHD-pNA	Caspase	Others
Ac-WEHD-pNA is a colorimetric substrate for caspase 1, 4, 5 and 14, which is utilized to measure the caspase activity .

HY-101899

Monochlorobimane 5+ Cited Publications Chlorobimane，mBBr	Fluorescent Dye	Others
Monochlorobimane (Chlorobimane) is a fluorescent dye (λ_ex=380 nm, λ_em=470 nm) to measure glutathione (GSH) in cellular assays .

HY-P3918

EGF-R (661-681) T669 Peptide	p38 MAPK	Others
EGF-R (661-681) T669 Peptide is a MAPK substrate that can used to measure MAPK catalytic activity .

HY-129867

Z-Leu-Leu-Leu-AMC Z-LLL-AMC	Proteasome	Others
Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome .

HY-D1624

3,3'-Diheptylthiacarbocyanine iodide	Fluorescent Dye	Others
3,3′-Diheptylthiacarbocyanine iodide is a cyanine dye for measuring membrane potential. (λ_ex=562 nm, λ_em=575 nm) .

HY-N11425

Benzydamine N-Oxide	Others	Others
Benzydamine N-Oxide is a metabolite of Benzydamine. Benzydamine N-Oxide can be used to measure flavin-containing monooxygenase activity .

HY-E70260

16-NBD-16:0 Coenzyme A triammonium	Acyltransferase	Others
16-NBD-16:0 Coenzyme A triammonium can be used as a substrate to measure the in vitro activity of other Acyltransferase .

HY-137942

1-Naphthyl phosphate disodium salt, 98% α-Naphthyl phosphate disodium salt, 98%	Biochemical Assay Reagents	Others
1-Naphthyl phosphate disodium salt, 98% is a histochemical substrate for acidic and alkaline phosphatases, and can also be used as a substrate for measuring prostatic acid phosphatase.

HY-P4920

Mca-SEVNLDAEFK(Dnp)-NH2	Fluorescent Dye	Others
Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1 .

HY-W479534

Decanoyl m-Nitroaniline DemNA	Biochemical Assay Reagents	Others
Decanoyl m-Nitroaniline (DemNA) is a nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity (Ab = 410 nm).

HY-118210

PHOP	FAAH	Metabolic Disease
PHOP is a fatty acid amide hydrolase (FAAH) inhibitor used to assess inhibitory activity in a fluorometric assay. PHOP can determine FAAH activity by measuring the amount of 4-pyridin-1-ylbutyric acid released by the enzyme in rat brain microsomes. PHOP demonstrates potential as a FAAH inhibitor and can directly measure FAAH activity by reversed-phase HPLC and fluorescence detection, providing a basis for the development of new inhibitors.

HY-139407

3-C12-NBD-cholesterol 3-Dodecanoyl-NBD-cholesterol	Fluorescent Dye	Others
3-C12-NBD-cholesterol is a fluorescent cholesterol analog that can be used for measuring membrane and intracellular trafficking dynamics .

HY-131682

3-C6-NBD-cholesterol 3-Hexanoyl-NBD-cholesterol	Fluorescent Dye	Others
3-C6-NBD-cholesterol is a fluorescent analog of Chol that can be used to measure the kinetics of membrane and intracellular trafficking .

HY-113844

Ac-Gly-Lys-OMe	Ser/Thr Protease	Others
Ac-Gly-Lys-OMe is a substrate for urokinase. Ac-Gly-Lys-OMe can be used to measure the effects of small molecule inhibitors on urokinase activity .

HY-D2284

SGPL1 fluorogenic substrate Sphingosine-1-phosphate lyase fluorogenic substrate	Fluorescent Dye	Cancer
SGPL1 fluorogenic substrate is the fluorogenic substrate of sphingosine-1-phosphate lyase (SGPL1) that can be used to measure the activity of SGPL1 .

HY-131475A

Naphthol AS-BI phosphate disodium hydrate	Biochemical Assay Reagents	Others
Naphthol AS-BI phosphate (disodium hydrate) is used as a substrate for determining the activity of both alkaline and acidic phosphatases; it can also be used to measure the activity of individual cell acid phosphatase.

HY-W012669

Phthalaldehyde Phthaldialdehyde	Biochemical Assay Reagents	Others
Phthalaldehyde is a biochemical assay reagent, which modifies the amino acid and measure the derivative through HPLC. Phthalaldehyde forms a fluorescent compound with α-amino group .

HY-D0075

DHPDS disodium salt	Fluorescent Dye	Others
DHPDS disodium salt is a pH-sensitive fluorescent dye. DHPDS disodium salt is used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver .

HY-P4018

HIV Protease Substrate IV	HIV Protease	Infection
HIV Protease Substrate IV is a substrate of HIV protease. HIV Protease Substrate IV can be used to measure the activity of HIV (human immunodeficiency virus) -1 protease .

HY-128425A

N-Carbamoyl-L-aspartic acid L-Ureidosuccinic acid	Endogenous Metabolite	Others
N-Carbamoyl-L-aspartic acid is intermediate of pyrimidine (HY-Y0519) metabolism. N-Carbamoyl-L-aspartic acid can be used to measure enzyme activity of dihydroorotase (DHOse) .

HY-126857A

5-Hydroxyomeprazole sodium	Drug Metabolite	Others
5-Hydroxyomeprazole sodium is the major metabolite of Omeprazole (HY-B0113). Measuring 5-Hydroxyomeprazole levels in plasma can determine the extent of Omeprazole metabolism .

HY-P10317

Suc-YVAD-AMC	Fluorescent Dye	Others
Suc-YVAD-AMC is used to measure the cysteine proteins of the proteasome.Suc-YVAD-AMC releases fluorescent AMC when cleaved by cysteine proteases to assess the enzymatic activity of the proteasome .

HY-D1457

DND-189	Fluorescent Dye	Others
DND-189, a low-pH fluorescent probe, is sensitive to neutral and low pH range. DND-189 can be used to measure the pH of acidic organelles .

HY-D1678

5(6)-Carboxynaphthofluorescein diacetate	Fluorescent Dye	Others
5(6)-Carboxynaphthofluorescein diacetate is a fluorescent substrate for esterase assays that can be cleaved by intracellular esterases, producing red fluorescence to measure enzyme activity (Ex = 590 nm; Em = 645 nm) .

HY-134432A

Boc-Gln-Ala-Arg-AMC hydrochloride	Ser/Thr Protease	Others
Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC hydrochloride can also be used for measuring the proteolytic activity of TMPRSS2 .

HY-E70082

Fructosyl amino acid oxidase	Others	Metabolic Disease
Fructosyl amino acid oxidase can be used to measure glycosylated protein. Glycosylated protein, especially glycosylated hemoglobin A1c, is an important marker to evaluate the efficacy of diabetes treatment .

HY-134432B

Boc-Gln-Ala-Arg-AMC acetate	Ser/Thr Protease	Others
Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2 .

HY-P2558

GSK3 Substrate, α, β subunit	GSK-3	Others
GSK3 Substrate, α, β subunit is peptide substrate for glycogen synthase kinase-3 (GSK-3) and can be used to measure GSK-3 activity .

HY-P2617

Ac-WEHD-AFC	Caspase	Inflammation/Immunology Cancer
Ac-WEHD-AFC is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation .

HY-107850S

Pregnanediol-d5 NSC 1612-d₅; NSC 47462-d₅	Endogenous Metabolite	Metabolic Disease
Pregnanediol-d₅ is the deuterium labeled Pregnanediol. Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo[1].

HY-D1705

Ac-ANW-AMC	Proteasome	Inflammation/Immunology
Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm) .

HY-158784

Arachidonoyl m-nitroaniline	FAAH	Others
Arachidonoyl m-Nitroaniline (AmNA) is one of several nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity. Arachidonoyl m-Nitroaniline is a FAAH substrate .

HY-B1178R

Cotinine (Standard)	Endogenous Metabolite nAChR	Cardiovascular Disease Inflammation/Immunology
Cotinine (Standard) is the analytical standard of Cotinine. This product is intended for research and analytical applications. Cotinine ((-)-Cotinine), an alkaloid in tobacco and a major metabolite of nicotine, is used as a biological indicator to measure the composition of tobacco smoke

HY-111391R

Resazurin sodium (Standard)	Bacterial	Others
Resazurin (sodium) (Standard) is the analytical standard of Resazurin (sodium). This product is intended for research and analytical applications. Resazurin sodium (Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.

HY-117992

BR103	Complement System	Others
BR103 is a C3aR-specific small molecule ligand. BR103 can be used to measure ligand affinity for a G protein-coupled receptor for saturation and competitive binding .

HY-D0980

Biotin-DADOO Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin	Biochemical Assay Reagents	Metabolic Disease
Biotin-DADOO is a biotinylation reagent, which can be used to synthesize a biotin-estradiol conjugate (i.e., biotin-DADOO-estradiol) to develop a direct, broad range enzyme immunoassay to measure plasma estradiol concentrations.

HY-P3362

Ac-IETD-AMC	Fluorescent Dye	Others
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .

Cat. No.	Product Name	Type

HY-D0936

SPQ	Fluorescent Dyes/Probes
SPQ is being used to examine and measure membrane chloride transport mechanisms.

HY-D0789

ANTS	Fluorescent Dyes/Probes
ANTS is a fluorescent dye. ANTS and DPX are encapsulated in liposomes can be an effective approach for measuring membrane leakage .

HY-111391

Resazurin sodium 3 Publications Verification Diazoresorcinol sodium	Fluorescent Dyes/Probes
Resazurin sodium (Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.

HY-101899

Monochlorobimane 5+ Cited Publications Chlorobimane，mBBr	Fluorescent Dyes/Probes
Monochlorobimane (Chlorobimane) is a fluorescent dye (λ_ex=380 nm, λ_em=470 nm) to measure glutathione (GSH) in cellular assays .

HY-131013

GSHtracer	Dyes
GSHtracer is a ratiometric probe for measuring of GSH levels. GSHtracer exhibits Ex/Em from 520/580 nm to 430/510 nm (upon GSH binding) .

HY-130210

Oxonol V	Fluorescent Dyes/Probes
Oxonol V is a slow-response sensitive probe for measuring cellular membrane potential.

HY-D1750

Rhodamine B thiolactone	Fluorescent Dyes/Probes
Rhodamine B thiolactone is a high-sensitive Hg ²⁺ indicator used for measuring Hg ²⁺ concentration.

HY-D1624

3,3'-Diheptylthiacarbocyanine iodide	Fluorescent Dyes/Probes
3,3′-Diheptylthiacarbocyanine iodide is a cyanine dye for measuring membrane potential. (λ_ex=562 nm, λ_em=575 nm) .

HY-W479534

Decanoyl m-Nitroaniline DemNA	Dyes
Decanoyl m-Nitroaniline (DemNA) is a nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity (Ab = 410 nm).

HY-D2284

SGPL1 fluorogenic substrate Sphingosine-1-phosphate lyase fluorogenic substrate	Fluorescent Dyes/Probes
SGPL1 fluorogenic substrate is the fluorogenic substrate of sphingosine-1-phosphate lyase (SGPL1) that can be used to measure the activity of SGPL1 .

HY-D0075

DHPDS disodium salt	Fluorescent Dyes/Probes
DHPDS disodium salt is a pH-sensitive fluorescent dye. DHPDS disodium salt is used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver .

HY-D1457

DND-189	Fluorescent Dyes/Probes
DND-189, a low-pH fluorescent probe, is sensitive to neutral and low pH range. DND-189 can be used to measure the pH of acidic organelles .

HY-D1678

5(6)-Carboxynaphthofluorescein diacetate	Fluorescent Dyes/Probes
5(6)-Carboxynaphthofluorescein diacetate is a fluorescent substrate for esterase assays that can be cleaved by intracellular esterases, producing red fluorescence to measure enzyme activity (Ex = 590 nm; Em = 645 nm) .

HY-134432B

Boc-Gln-Ala-Arg-AMC acetate	Dyes
Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2 .

HY-D1705

Ac-ANW-AMC	Fluorescent Dyes/Probes
Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm) .

HY-111391R

Resazurin sodium (Standard)	Fluorescent Dyes/Probes
Resazurin (sodium) (Standard) is the analytical standard of Resazurin (sodium). This product is intended for research and analytical applications. Resazurin sodium (Diazoresorcinol sodium) is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.

HY-P3362

Ac-IETD-AMC	Fluorescent Dyes/Probes
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .

HY-D0808

Meldola blue	Dyes
Meldola blue is a biosensor for measuring lactate in serum based on screen-printed carbon electrodes modified with Meldola's Blue-Reinecke salt (MBRS-SPCE) coated with lactate dehydrogenase NAD+-dependent enzyme (from pig heart) and NAD+.

HY-W009458

3-Indoxyl phosphate sodium

3-IP sodium

Dyes

3-Indoxyl phosphate (3-IP) is a chromogenic and electrochemical substrate for alkaline phosphatase. Upon enzymatic cleavage by alkaline phosphatase, 3-indoxyl is released and subsequently oxidized to produce water-insoluble indigo, which can be quantified by colorimetric detection at 660 nm as a measure of alkaline phosphatase activity. 3-Indoxyl phosphate can also be converted to water-soluble leucoindigo by reduction of indigo in alkaline solution by sodium dithionite, which can be quantified by colorimetric detection at 415 nm or voltametric detection as a measure of alkaline phosphatase activity.2 3-Indoxyl phosphate has been used in ELISAs.

HY-D1894

5-Br-PAPS	Fluorescent Dyes/Probes
5-Br-PAPS is a highly specific Zn ²⁺ metallochromic indicator. 5-Br-PAPS is used in assays for measuring free Zn ²⁺ by forming a deeply colored red Zn ²⁺ complex .

HY-D2119

CQ-Lyso	Fluorescent Dyes/Probes
CQ-Lyso is a lysosome-targeting chromenoquinoline. CQ-Lyso is a fluorescent probe for measuring the pH of lysosomes in living cells using only single wavelength excitation. CQ-Lyso can visualize the dynamic pH changes in lysosomes .

HY-77962

2-Thiobarbituric acid	Fluorescent Dyes/Probes
2-Thiobarbituric acid is a commonly used colorimetric reagent for the detection of malondialdehyde (MDA), a marker of lipid peroxidation. 2-Thiobarbituric acid forms a complex with MDA that can be quantified by colorimetric detection at 532 nm as a measure of lipid peroxidation .

HY-D0163

Methyl Green 1 Publications Verification	DNA Stain
Methyl Green is a potent fluorescent dye. Methyl Green is a DNA stains of cells and electrophoretic gels. Methyl Green can be used as a stain for direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm .

HY-145499

XTT sodium hydrate	Fluorescent Dyes/Probes
XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator. It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.

HY-D0950A

Methyl Green zinc chloride	DNA Stain
Methyl Green zinc chloride is a potent fluorescent dye. Methyl Green zinc chloride is a DNA stains of cells and electrophoretic gels. Methyl Green zinc chloride can be used as direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm .

HY-100045

p-Nitrophenyl phosphorylcholine 4-Nitrophenylphosphorylcholine; 4-Nitrophenylphosphorylcholine; O-(4-Nitrophenylphosphoryl)choline	Fluorescent Dyes/Probes
p-Nitrophenyl phosphorylcholine (4-Nitrophenylphosphorylcholine) is a chromogenic substrate that is used to measure phospholipase C (PLC) activity. Hydrolysis of p-nitrophenylphosphorylcholine by PLC results in the liberation of p-nitrophenol, which can be measured at 405 nm at pH 7.2-7.5.

HY-131409

D-Val-Leu-Lys-pNA dihydrochloride D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride	Dyes
D-Val-Leu-Lys-pNA dihydrochloride (D-VLK-pNA dihydrochloride) is a colorimetric substrate for plasminolytic activity. D-Val-Leu-Lys-pNA dihydrochloride is catalytically bound and hydrolyzed by plasmin to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of plasminolytic activity .

HY-D1260

FM-red PSH-red	Fluorescent Dyes/Probes
FM-red (PSH-red) is a red-emitting and environment-sensitive probe for selectively detecting and labeling protein thiols. FM-red can be used to image protein sulfhydryl groups in live cells and in vivo. FM-red also could be used to measure of the redox states of thioredoxin (Trx) .

HY-D0018

DCIP sodium

Dichlorophenylindophenol sodium; DCPIP sodium; Indochlorophenol sodium

Dyes

DCIP sodium is a blue dye commonly used in various biochemical and biotechnological applications as an indicator of redox reactions. DCIP sodium has unique chemical properties that change color according to the oxidation state of the substance being tested. It is commonly used in enzyme assays, such as measuring the activity of succinate dehydrogenase, or in protein quantification methods, such as the Lowry assay.

HY-D2316

Flipper-TR probe	Fluorescent Dyes/Probes
Flipper-TR probe (Compound FliptR probe) is a fluorescent probe specifically designed to measure cell membrane tension. Flipper-TR probe reports changes in membrane tension through variations in its fluorescence lifetime. Flipper-TR probe is applicable to a wide range of organisms including bacteria, yeast, mammals, and plants .

HY-D2319

Mito Flipper-TR 27	Fluorescent Dyes/Probes
Mito Flipper-TR 27 is a fluorescent probe for measuring membrane tension in living cells. Mito Flipper-TR 27 accumulates in mitochondria because the strong internal negative membrane potential drives the permanent hydrophobic triphenylphosphine cation across the inner membrane and prevents its release, thus enabling it to be used for tracking mitochondria .

HY-P2628

Dabcyl-YVADAPV-EDANS	Fluorescent Dyes/Probes
Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K ⁺ deprivation-induced apoptosis of cerebellar granule neurons .

HY-15924

Thiazolyl Blue Maximum Cited Publications 118 Publications Verification MTT; Thiazolyl Blue Tetrazolium bromide; Methylthiazolyldiphenyl-tetrazolium bromide	Chromogenic Substrates
Thiazolyl Blue (MTT) is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells. Thiazolyl Blue is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD (P) H-oxidoreductases. Thiazolyl Blue is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis .

HY-137858

H-Gly-Arg-pNA hydrochloride Gly-Arg-4-NA hydrochloride; GR-pNA hydrochloride; GR p-itoailide hydrochloride	Dyes
H-Gly-Arg-pNA hydrochloride (GR-pNA hydrochloride) is a colorimetric substrate for thrombin. H-Gly-Arg-pNA is preferentially bound by thrombin and cleaves the Gly-Arg (GR) peptide sequence, releasing p-nitroaniline (pNA) that can be detected colorimetrically at 405 nm. H-Gly-Arg-pNA hydrochloride is used as a fluorescent dye to measure thrombin activity .

HY-D1545

Violamine R

Acid Violet 9

Dyes

Violamine R (Acid Violet 9) is a potent fluorophore. Violamine R shows environment and temperature-dependent photoluminescence (PL) intermittency in poly(vinyl alcohol) (PVOH) and potassium acid phthalate (KAP). Violamine R can be used to measure the temperatures spanning the glass-transition temperature (Tg) of the polymer host by the fluorescence intermittency or blinking in poly(vinyl alcohol) (PVA) .

HY-D2041

3-HTC	Fluorescent Dyes/Probes
3-HTC is a chemical fluorescent probe. 3-HTC reacts reversibly with thiols and disulfides, and can be used to measure dynamic GSH/GSSH ratios in vitro as well as to monitor the reversible redox status of whole cell lysates (λ_max: 448 nm in its reduced thiolate form, and a λ_max 370-410 nm for the oxidized mixed disulfide) .

HY-15914

DHBS DCHBS	Chromogenic Substrates
DHBS (3, 5-dichloro-2-hydroxybenzenesulfonate) is used in conjunction with 4-aminoantipyrine (4-AAP) (HY-W100990) and hydrogen peroxide (H₂O₂) for chromogenic quantitation of peroxidase in coupled enzymatic reactions. Component of Trinder reagent for use with peroxidase to measure generation of hydrogen peroxide in automated systems .

HY-118155

9-Amino-6-chloro-2-methoxyacridine	Fluorescent Dyes/Probes
9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H ⁺/solute antiport system .

HY-131131

5-CFDA-AM

Fluorescent Dyes/Probes

5-CFDA-AM is a cell-permeable esterase substrate that can be used as an active probe to measure enzyme activity and cell membrane integrity. 5-CFDA-AM is electroneutral and can enter the cell at a lower concentration than CFDA, where it is hydrolysed by intracellular esterases to produce carboxyfluorescein. Carboxyfluorescein contains an additional negative charge and can be better retained in the cell .

HY-143218

TPE-MI

2 Publications Verification

Tetraphenylethene maleimide

Fluorescent Dyes/Probes

TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells. TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .

HY-W010947

4-Methylumbelliferyl palmitate

Fluorescent Dyes/Probes

4-Methylumbelliferyl palmitate is an excellent fluorophore for measuring acid lipase in human leukocytes. Acidity and solvent have important influence on its fluorescence. 4-Methylumbelliferyl palmitate exists mainly as neutral molecular form which can be produced strong fluorescence at 445 nm in near neutral aqueous solutions, and exist mainly as anion form which can be produced stronger fluorescence at 445 nm in weak alkaline solutions .

HY-D0221

2,4,6-Tri-2-pyridinyl-1,3,5-triazine NSC 112125; 2,4,6-Tipyidyl-s-tiazie	Dyes
2,4,6-Tri-2-pyridinyl-1,3,5-triazine (NSC 112125) is a commonly used fluorescent dye for detecting iron. 2,4,6-Tri-2-pyridinyl-1,3,5-triazine forms a complex with Fe (II) and can be quantified as a measure of iron concentration by colorimetric detection at 594 nm .

HY-W013168

4-Nitrophenyl palmitate

4-Nitrophenyl hexadecanoate; p-Nitrophenyl Palmitate; pNpp

Dyes

4-Nitrophenyl palmitate (4-Nitrophenyl hexadecanoate; p-Nitrophenyl Palmitate) is a colorimetric lipase and esterase substrate. Upon enzymatic hydrolysis of 4-Nitrophenyl palmitate, 4-nitrophenol is released, which can be quantified by colorimetric detection at 410 nm as a measure of enzyme activity. 4-Nitrophenyl palmitate has been used to characterize the activity of various bacterial and mammalian enzymes, including Burkholderia and porcine pancreatic lipase.

HY-120971

N-Decanoyl p-Nitroaniline

DepNA

Fluorescent Dyes/Probes

N-Decanoyl p-nitroaniline (DepNA) is one of several nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.1 FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its endogenous substrate anandamide (AEA). It also will hydrolyze fatty acid amides with fewer carbons and fewer double bonds than arachidonate. Exposure of DepNA to FAAH activity results in the release of the yellow colorimetric dye p-nitroaniline (ε=13,500 at 410 nm). This allows the fast and convenient measurement of FAAH activity using a 96 well plate spectrophotometer.

Cat. No.	Product Name	Type

HY-101886

5-BrUTP sodium salt 5-Bromouridine 5'-triphosphate sodium salt	Gene Sequencing and Synthesis
5-BrUTP sodium salt can be used to label RNA to measure the transcription.

HY-W012669

Phthalaldehyde Phthaldialdehyde	Biochemical Assay Reagents
Phthalaldehyde is a biochemical assay reagent, which modifies the amino acid and measure the derivative through HPLC. Phthalaldehyde forms a fluorescent compound with α-amino group .

HY-D0980

Biotin-DADOO Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin	Biochemical Assay Reagents
Biotin-DADOO is a biotinylation reagent, which can be used to synthesize a biotin-estradiol conjugate (i.e., biotin-DADOO-estradiol) to develop a direct, broad range enzyme immunoassay to measure plasma estradiol concentrations.

HY-15927

4-Nitrophenyl β-D-glucopyranoside 1 Publications Verification	Enzyme Substrates
4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside can be used to measure of β-glucosidase activity .

HY-W129633

2,6-Dichlorophenolindophenol sodium hydrate DCIP sodium hydrate; DPIP sodium hydrate	Indicators
2,6-Dichlorophenolindophenol (sodium hydrate) is a blue reduction dye used as an indicator for measuring the content of vitamin C.

HY-137942

1-Naphthyl phosphate disodium salt, 98% α-Naphthyl phosphate disodium salt, 98%	Enzyme Substrates
1-Naphthyl phosphate disodium salt, 98% is a histochemical substrate for acidic and alkaline phosphatases, and can also be used as a substrate for measuring prostatic acid phosphatase.

HY-131475A

Naphthol AS-BI phosphate disodium hydrate	Carbohydrates
Naphthol AS-BI phosphate (disodium hydrate) is used as a substrate for determining the activity of both alkaline and acidic phosphatases; it can also be used to measure the activity of individual cell acid phosphatase.

HY-W101382

5-Bromo-6-chloro-3-indolyl-N-acetyl-β-D-glucosaminide, 98%	Carbohydrates
5-Bromo-6-chloro-3-indolyl-N-acetyl-β-D-glucosaminide, 98% is a chromogenic substrate used to measure β-galactosidase activity in food, enzyme substrates, and culture media.

HY-W293502

2-Chloro-4-nitrophenyl-β-D-galactopyranoside 2-Chloro-4-nitrophenyl-beta-D-galactopyranoside	Carbohydrates
2-Chloro-4-nitrophenyl-β-D-galactopyranoside is a chromogenic substrate used for testing enzyme activity. It is commonly used in molecular biology research to detect and measure the activity of β-galactosidase (biosynth: EC03318).

HY-W012669R

Phthalaldehyde (Standard)	Biochemical Assay Reagents
Phthalaldehyde (Standard) is the analytical standard of Phthalaldehyde. This product is intended for research and analytical applications. Phthalaldehyde is a biochemical assay reagent, which modifies the amino acid and measure the derivative through HPLC. Phthalaldehyde forms a fluorescent compound with α-amino group .

HY-116022B

4-Nitrophenyl phosphate ditromethamine p-Nitrophenyl phosphate ditromethamine	Enzyme Substrates
4-Nitrophenyl phosphate ditromethamine is an enzyme substrate commonly used in biochemical assays to measure the activity of various phosphatases, including alkaline phosphatase. 4-Nitrophenylphosphate has unique chemical properties that allow it to be hydrolyzed by phosphatases, releasing a yellow product that can be detected spectrophotometrically.

HY-W104635

6-Bromo-2-naphthyl-β-D-galactopyranoside 6-Bromo-2-naphthyl-beta-D-galactopyranoside	Carbohydrates
6-Bromo-2-naphthyl-β-D-galactopyranoside is a chromogenic substrate commonly used to measure β-galactosidase enzyme activity in food, enzyme substrates, and culture media. Upon hydrolysis by β-galactosidase, it generates a yellow precipitate indicating the enzyme's presence.

HY-131490

Tetrazolium violet

Violet tetrazolium

Indicators

Tetrazolium violet is a redox indicator commonly used in various biochemical assays to measure cell viability and metabolic activity. Tetrazolium Violet has unique chemical properties that allow it to be reduced by cellular enzymes such as dehydrogenases to form a purple formazan product that can be detected spectrophotometrically. This makes it a useful tool for assessing cell health and growth in culture or tissue samples.

HY-137872

L-Leucyl-4-nitroanilide hydrochloride

Enzyme Substrates

L-Leucyl-4-nitroanilide hydrochloride is a commonly used substrate in various biochemical assays to measure the activity of enzymes that cleave peptide bonds, such as proteases. L-Leucine p-nitroanilide hydrochloride has unique chemical properties that allow it to be cleaved by these enzymes to form a yellow product called p-nitroaniline. This makes it a useful tool for detecting and quantifying protease activity in biological samples such as blood or tissue extracts.

HY-137815

4-Nitrophenyl α-L-rhamnopyranoside

Carbohydrates

4-Nitrophenyl α-L-rhamnopyranoside is a commonly used substrate in various biochemical assays to measure the activity of enzymes that hydrolyze rhamnose, such as α-L-rhamnosidase. 4-Nitrophenyl α-L-rhamnopyranoside has unique chemical properties that allow it to be hydrolyzed by these enzymes to form a yellow product called p-nitrophenol. This makes it a useful tool for detecting and quantifying rhamnohydrolase activity in biological samples or microbial cultures.

HY-W698964

2′-Hydroxy-5′-nitrohexadecanamide

Indicators

2′-Hydroxy-5′-nitrohexadecanamide is a lysosomal hydrolase inhibitor and is a lipid containing pentadecanoic acid and a terminal nitrophenol in its structure. 2′-Hydroxy-5′-nitrohexadecanamide can cause intracellular lipid accumulation by inhibiting lysosomal hydrolase activity. Additionally, 2′-Hydroxy-5′-nitrohexadecanamide can be used to synthesize chromogenic substrates for measuring sphingolipase activity .

HY-15932

TOOS

TOOS sodium salt

Biochemical Assay Reagents

TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound .

HY-137249

Resorufin-β-D-galactopyranoside

Enzyme Substrates

Resorufin-β-D-galactopyranoside is a commonly used substrate in various biochemical assays to measure the activity of β-galactosidase, an important enzyme involved in lactose metabolism and regulation of gene expression. Resorufin-β-D-galactopyranoside has unique chemical properties and can be hydrolyzed by β-galactosidase to form a red fluorescent product called resorufin. This makes it a useful tool for detecting and quantifying β-galactosidase activity in biological samples such as bacteria or mammalian cells.

HY-W014449

4-Nitrophenyl butyrate

Enzyme Substrates

4-Nitrophenyl butyrate consists of butyric acid chains esterified with 4-nitrophenol groups, thus giving it a yellow color. This compound is commonly used as a substrate in enzyme assays to measure esterase and lipase activity. When these enzymes cleave the ester bond, the nitrophenol group is released and the color changes from yellow to orange. Thus, the rate of color change can be used to determine enzyme activity. In addition, 4-Nitrophenyl butyrate can also be used as organic synthesis reagent and dye intermediate.

HY-W017386

3-Methyl-2-oxovaleric acid sodium

1 Publications Verification

Enzyme Substrates

3-Methyl-2-oxovaleric acid, sodium salt belongs to the class of carboxylic acids, consisting of a five-carbon chain with methyl, carboxyl and ketone groups. This compound is commonly used as an analytical reagent in biochemical and medical research, especially for the detection and quantification of 2-ketoacids. It can also be used as a substrate in enzyme assays to measure the activity of certain enzymes involved in amino acid metabolism. In addition, 3-Methyl-2-oxovaleric acid, sodium salt may have potential research roles in various diseases such as diabetes, cancer and cardiovascular disease.

HY-D0714

Tetrazolium Red

3 Publications Verification

2,3,5-Triphenyltetrazolium chloride; TPTZ; TTC

Enzyme Substrates

Tetrazolium Red (2,3,5-Triphenyltetrazolium chloride; TTC) is a not brain-penetrant, colorless, water-soluble dye that is reduced by mitochondrial enzymes to a deep red, water-insoluble compound (formazan) mainly in the mitochondria of living cells. Tetrazolium Red is used to observe the activity of dehydrogenase, and it turns colorless to red when exposed to hydrogen. Tetrazolium Red distinguishes between surviving and infarcted brain tissue after stroke. Tetrazolium Red has been used to stain heart tissue to measure the extent of acute lesions and also used to stain brain tissue to detect the size of the infarcted area. The absorption wavelength of Tetrazolium Red is 570 nm .

HY-W250129

2,3,4,5-Tetrafluorobenzoyl chloride

Biochemical Assay Reagents

2,3,4,5-Tetrafluorobenzoyl chloride is a fluorinated organic compound that belongs to the class of benzoyl chlorides. It is a colorless liquid with a pungent smell and is mainly used as an intermediate in the synthesis of various pharmaceutical and pesticide compounds. 2,3,4,5-Tetrafluorobenzoyl chloride is an acylating agent that can react with a variety of nucleophiles, including amines, alcohols, and thiols, to form amides, esters, or thioesters, respectively. Its unique fluorine-containing structure can impart desired properties to target molecules, such as increased lipophilicity or increased stability against metabolic degradation. However, due to its high reactivity and potential health hazards, proper safety measures and handling procedures must be followed when using this compound.

HY-W127391

1,2-Dilaurin

(Rac)-1,2-Didodecanoylglycerol

Drug Delivery

1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).

Cat. No.	Product Name	Target	Research Area

HY-P5965

BiP substrate	Peptides	Others
BiP substrate is a peptide substrate of BiP that can be used to measure the BiP ATPase activity .

HY-P4920

Mca-SEVNLDAEFK(Dnp)-NH2	Fluorescent Dye	Others
Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1 .

HY-P3920

Cys-Kemptide	PKA	Cancer
Cys-Kemptide is a cysteine-terminated substrate peptide that can used to measure protein kinase A (PKA) activity .

HY-P5500

Peptide P1	Peptides	Others
Peptide P1 is a biological active peptide. (commonly used to measure the degree of scrambling during ETD analysis)

HY-P4326

Boc-Val-Pro-Arg-AMC	Fluorescent Dye	Others
Boc-Val-Pro-Arg-MCA is a sensitive fluorogenic substrate for measuring trypsin-like serine proteases activity .

HY-P4496

Tos-Gly-Pro-Lys-pNA	Peptides	Others
Tos-Gly-Pro-Lys-pNA is a substrate for the serine protease ALP and can be used to measure the activity of this enzyme .

HY-P10236

Ac-WEHD-pNA	Caspase	Others
Ac-WEHD-pNA is a colorimetric substrate for caspase 1, 4, 5 and 14, which is utilized to measure the caspase activity .

HY-P3918

EGF-R (661-681) T669 Peptide	p38 MAPK	Others
EGF-R (661-681) T669 Peptide is a MAPK substrate that can used to measure MAPK catalytic activity .

HY-129867

Z-Leu-Leu-Leu-AMC Z-LLL-AMC	Proteasome	Others
Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome .

HY-P4429

Z-YVAD-AFC	Peptides	Others
Z-YVAD-AFC is a fluorescent substrate for Caspase-1, which can be used to detect and measure the activity of Caspase-1 .

HY-P2513

Src Optimal Peptide Substrate	Peptides	Others
Src Optimal Peptide Substrate is a highly specific Src substrate. Src Optimal Peptide Substrate can used to measure the Src activity .

HY-P4285

β-Aspartylalanine	Peptides	Others
β-Aspartylalanine is a substrate for β-aspartyl peptidase and used to measure β-aspartyl peptidase activity in fecal supernatants .

HY-P4658

H-Val-Ala-pNA	Peptides	Others
H-Val-Ala-pNA is a substrate for the dipeptide aminopeptidase (DPAPase) of Streptococcus bovis. H-Val-Ala-pNA can be used to measure the activity of the protease .

HY-113844

Ac-Gly-Lys-OMe	Ser/Thr Protease	Others
Ac-Gly-Lys-OMe is a substrate for urokinase. Ac-Gly-Lys-OMe can be used to measure the effects of small molecule inhibitors on urokinase activity .

HY-P4462

D-Leu-Thr-Arg-pNA	Peptides	Others
D-Leu-Thr-Arg-pNA is a substrate for γ-Tryptase, and can be used to measure the effects of small molecule inhibitors on γ-Tryptase activity .

HY-P4018

HIV Protease Substrate IV	HIV Protease	Infection
HIV Protease Substrate IV is a substrate of HIV protease. HIV Protease Substrate IV can be used to measure the activity of HIV (human immunodeficiency virus) -1 protease .

HY-P10317

Suc-YVAD-AMC	Fluorescent Dye	Others
Suc-YVAD-AMC is used to measure the cysteine proteins of the proteasome.Suc-YVAD-AMC releases fluorescent AMC when cleaved by cysteine proteases to assess the enzymatic activity of the proteasome .

HY-134432B

Boc-Gln-Ala-Arg-AMC acetate	Ser/Thr Protease	Others
Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2 .

HY-P2558

GSK3 Substrate, α, β subunit	GSK-3	Others
GSK3 Substrate, α, β subunit is peptide substrate for glycogen synthase kinase-3 (GSK-3) and can be used to measure GSK-3 activity .

HY-P2617

Ac-WEHD-AFC	Caspase	Inflammation/Immunology Cancer
Ac-WEHD-AFC is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation .

HY-P3362

Ac-IETD-AMC	Fluorescent Dye	Others
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .

HY-P2617A

Ac-WEHD-AFC TFA	Caspase	Inflammation/Immunology Cancer
Ac-WEHD-AFC TFA is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC TFA can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation .

HY-P2615

Ac-VDVAD-AFC	Fluorescent Dye	Cancer
Ac-VDVAD-AFC is a caspase-specific fluorescent substrate. Ac-VDVAD-AFC can measure caspase-3-like activity and caspase-2 activity and can be used for the research of tumor and cancer .

HY-P2620

Ac-LETD-AFC	Fluorescent Dye	Metabolic Disease Cancer
Ac-LETD-AFC is a caspase-8 fluorogenic substrate. Ac-LETD-AFC can measure caspase-8 fluorogenic activity and can be used for the research of cancer cell apoptosis and oxidative stress metabolism .

HY-P3748

Casein Kinase II Receptor Peptide	Casein Kinase	Others
Casein Kinase II Receptor Peptide is a substrate for casein kinase II with an K_m value of 500 µM. Casein Kinase II Substrate can be used for measure casein kinase II activity in crude enzyme preparations .

HY-P10344

MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2	Fluorescent Dye	Infection
MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 is a fluorescent substrate used for fluorescence resonance energy transfer (FRET) protease assays. This substrate is employed to measure the activity of SARS-CoV-2 3CLpro .

HY-P4443

Ac-GAK-AMC	Peptides	Others
Ac-GAK-AMC is a fluorescent substrate that can be used to measure protease activity. AMC (7-amino-4-methylcoumarin) is a fluorescent group. In the presence of protease, the protease will hydrolyze Ac-GAK-AMC into a fluorescent product .

HY-P3814

S6 Kinase Substrate Peptide 32	Ribosomal S6 Kinase (RSK)	Cancer
S6 Kinase Substrate Peptide 32 is a substrate of Ribosomal S6 Kinase (RSK). S6 Kinase Substrate Peptide 32 can be used to measure the activity of RSKs which phosphorylate ribosomal protein S6 .

HY-P2615A

Ac-VDVAD-AFC TFA	Fluorescent Dye	Cancer
Ac-VDVAD-AFC TFA is a caspase-specific fluorescent substrate. Ac-VDVAD-AFC TFA can measure caspase-3-like activity and caspase-2 activity and can be used for the research of tumor and cancer .

HY-P2295

Dabcyl-KTSAVLQSGFRKME-Edans TFA 1 Publications Verification	SARS-CoV	Others
Dabcyl-KTSAVLQSGFRKME-Edans TFA is a fluorogenic peptide. Dabcyl-KTSAVLQSGFRKME-Edans TFA is used as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKME-Edans TFA has the potential for study 2019-nCoV (COVID-19) infection .

HY-131409

D-Val-Leu-Lys-pNA dihydrochloride D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride	Fluorescent Dye	Others
D-Val-Leu-Lys-pNA dihydrochloride (D-VLK-pNA dihydrochloride) is a colorimetric substrate for plasminolytic activity. D-Val-Leu-Lys-pNA dihydrochloride is catalytically bound and hydrolyzed by plasmin to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of plasminolytic activity .

HY-120833

Ac-Ile-Glu-Thr-Asp-pNA	Caspase	Others
Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity .

HY-P4417A

Ac-IEPD-AMC TFA	Fluorescent Dye	Others
Ac-IEPD-AMC TFA is a fluorescent substrate used to measure protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC fluoresces under UV light irradiation and can emit fluorescent signals .

HY-P2628

Dabcyl-YVADAPV-EDANS	Fluorescent Dye	Others
Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K ⁺ deprivation-induced apoptosis of cerebellar granule neurons .

HY-P4400

Z-VDVAD-AFC	Fluorescent Dye	Others
Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals .

HY-P2296

Abz-FRLKGGAPIKGV-EDDNP TFA	Fluorescent Dye	Others
Abz-FRLKGGAPIKGV-EDDNP TFA is a fluorogenic substrate used to measure the enzymatic activities of protease forms, such as papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV). Abz-FRLKGGAPIKGV-EDDNP TFA has the potential for study 2019-nCoV (COVID-19) infection .

HY-123275A

H-D-Phe-Pip-Arg-pNA hydrochloride S-2238 hydrochloride	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .

HY-123275

H-D-Phe-Pip-Arg-pNA S-2238	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .

HY-123275C

H-D-Phe-Pip-Arg-pNA dihydrochloride S-2238 dihydrochloride	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .

HY-123275B

H-D-Phe-Pip-Arg-pNA acetate S-2238 acetate	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .

HY-P5378

Ac-KQKLR-AMC Cathepsin S substrate	Peptides	Others
Ac-KQKLR-AMC (Cathepsin S substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.This peptide is a cathepsin S substrate fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). It can be used to measure cathepsin S activity.)

Cat. No.	Product Name

HY-K0314

ATP Assay Kit
MCE ATP Assay Kit provides a rapid method to measure intracellular ATP. The kit is suitable for ATP determination in cells, tissue, and other biological samples.

HY-K0319

Lipid Peroxidation (MDA) Assay Kit 1 Publications Verification
MCE Lipid Peroxidation (MDA) Assay Kit is suitable for measuring MDA levels in a variety of samples including plasma, serum, urine, tissues or cell lysates.

HY-K0321

Fumarase Activity Assay Kit (WST-8)
MCE Fumarase Activity Assay Kit (WST-8) can be used to measure the amount of fumarase present in biological samples.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-107850

Pregnanediol NSC 1612; NSC 47462	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo .

HY-N11425

Benzydamine N-Oxide	Structural Classification Natural Products Source classification Endogenous metabolite	Others
Benzydamine N-Oxide is a metabolite of Benzydamine. Benzydamine N-Oxide can be used to measure flavin-containing monooxygenase activity .

HY-128425A

N-Carbamoyl-L-aspartic acid L-Ureidosuccinic acid	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Carbamoyl-L-aspartic acid is intermediate of pyrimidine (HY-Y0519) metabolism. N-Carbamoyl-L-aspartic acid can be used to measure enzyme activity of dihydroorotase (DHOse) .

HY-107858

Veratryl alcohol 3,4-Dimethoxybenzyl alcohol	Structural Classification Natural Products Microorganisms Classification of Application Fields Other Diseases Disease Research Fields	Endogenous Metabolite
Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H₂O₂ and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP) .

HY-131576A

Thymidine 5′-diphosphate sodium dTDP sodium	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Thymidine 5′-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg ²⁺. Thymidine 5′-diphosphate sodium is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .

HY-114464

11-Beta-hydroxyandrostenedione 4-Androsten-11β-ol-3,17-dione	Source classification Endogenous metabolite Disease Research Fields Endocrinology Steroids	Endogenous Metabolite 11β-HSD
11-Beta-hydroxyandrostenedione (4-Androsten-11β-ol-3,17-dione) is a steroid mainly found in the the adrenal origin (11β-hydroxylase is present in adrenal tissue, but absent in ovarian tissue). 11-Beta-hydroxyandrostenedione is a 11β-hydroxysteroid dehydrogenase (11βHSD) isozymes inhibitor. As 4-androstenedione increases, measuring plasma 11-Beta-hydroxyandrostenedione can distinguish the adrenal or ovarian origin of hyperandrogenism .

HY-N7259B

(±)-Isomenthone	Natural Products Labiatae Achyrocline flaccida (Weinm.) DC. Plants	Others
(±)-Isomenthone is a naturally active compound, a racemate of Isomenthone. (±)-Isomenthone has optical activity and is mainly used to measure the activity .

HY-B1178R

Cotinine (Standard)	Alkaloids Structural Classification Pyrrole Alkaloids Nicotiana tabacum L. Source classification Pyridine Alkaloids Solanaceae Plants Endogenous metabolite	Endogenous Metabolite nAChR
Cotinine (Standard) is the analytical standard of Cotinine. This product is intended for research and analytical applications. Cotinine ((-)-Cotinine), an alkaloid in tobacco and a major metabolite of nicotine, is used as a biological indicator to measure the composition of tobacco smoke

HY-W438378

4-Hydroxy-3-methoxyphenylglycol piperazine HMPG piperazine	Structural Classification Monophenols Source classification Phenols Endogenous metabolite	Biochemical Assay Reagents
4-Hydroxy-3-methoxyphenylglycol piperazine (HMPG piperazine) is a salt of HMPG combined with piperazine. HMPG is a metabolite of adrenaline and norepinephrine and is an important marker of catecholamine hormone metabolism in the body. 4-Hydroxy-3-methoxyphenylglycol piperazine is used as a standard in clinical laboratories to accurately measure the HMPG content in urine .

HY-131576

Thymidine 5′-diphosphate dTDP	Infection Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Thymidine 5′-diphosphate (dTDP) is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg ²⁺. Thymidine 5′-diphosphate is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .

HY-B1178

Cotinine 1 Publications Verification (-)-Cotinine; (S)-Cotinine; NIH-10498	Alkaloids Structural Classification Pyrrole Alkaloids Nicotiana tabacum L. Classification of Application Fields Source classification Other Diseases Pyridine Alkaloids Solanaceae Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite nAChR
Cotinine ((-)-Cotinine) is an orally active alkaloid found in tobacco and is the primary metabolite of nicotine. Cotinine is metabolized by CYP2A13 into trans-3'-hydroxycotinine. Cotinine is used as a biomarker to measure exposure to tobacco smoke components. Cotinine has vasodepressor activity. The mixture of cotinine and nicotine (Nicotine) has antiproliferative activity against pterygium. (S)-(-)-Cotinine activates nicotinic acetylcholine receptors (nAChR) in a calcium-dependent manner, leading to the release of dopamine (Dopamine, HY-B0451). Cotinine ((-)-Cotinine) is used in research related to cardiovascular and inflammatory diseases .

Cat. No.	Product Name	Chemical Structure

HY-107850S

Pregnanediol-d5
Pregnanediol-d₅ is the deuterium labeled Pregnanediol. Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo[1].

HY-W040047S

Pregnanediol 3-glucuronide-13C5
Pregnanediol 3-glucuronide- ¹³C₅ is ¹³C-labeled Pregnanediol (HY-107850) Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo.

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