2. Gene
  3. DDX6 - DEAD-box helicase 6 Gene

DDX6 - DEAD-box helicase 6 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as P54; RCK; HLR2; IDDILF; Rck/p54

Gene ID: 1656 | Gene type: protein coding

About DDX6

Cytogenetic location: 11q23.3 Genomic coordinates (GRCh38): 11:118,747,763-118,791,744 (from NCBI)

This gene has 7 transcripts (splice variants), 207 orthologues, 38 paralogues and is associated with 58 phenotypes. Ubiquitous expression in brain (RPKM 27.6), lymph node (RPKM 26.5) and 25 other tissues.

Summary

This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012]

DDX6 Products(2)

mRNA Protein Name
NM_001257191.3 NP_001244120.1 probable ATP-dependent RNA helicase DDX6
NM_004397.6 NP_004388.2 probable ATP-dependent RNA helicase DDX6
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16364915 GOA
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
24768540 GOA
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within P-body assembly IDA
IDA: Inferred from direct assay
20826699 GOA
involved in P-body assembly IDA
IDA: Inferred from direct assay
27342281 GOA
involved in P-body assembly IMP
IMP: Inferred from mutant phenotype
25995375 GOA
acts upstream of positive effect miRNA-mediated gene silencing by inhibition of translation IDA
IDA: Inferred from direct assay
27342281 GOA
involved in negative regulation of translation IDA
IDA: Inferred from direct assay
27342281 GOA
involved in viral RNA genome packaging IMP
IMP: Inferred from mutant phenotype
22022269 GOA
Cellular Component GO Annotation Evidence Reference Source
located in P-body IDA
IDA: Inferred from direct assay
16699599 GOA
located in P-body IMP
IMP: Inferred from mutant phenotype
22022269 GOA
part of RISC complex IDA
IDA: Inferred from direct assay
20616046 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
26184334 GOA
located in cytoplasmic stress granule IDA
IDA: Inferred from direct assay
17392519 GOA
located in nucleus IDA
IDA: Inferred from direct assay
26184334 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DDX6 Protein Structure

DEAD

DEAD: DEAD/DEAH box helicase (121 - 286)

Helicase_C

Helicase_C: Helicase conserved C-terminal domain (353 - 429)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 483 a.a.
Protein Preferred Names Protein Names

probable ATP-dependent RNA helicase DDX6

ATP-dependent RNA helicase p54

DDX6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra DDX6 P26196 PNMA5 Homo sapiens Q96PV4
Y2H Prey Pooling
25416956
Intra DDX6 P26196 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
Intra DDX6 P26196 KRT40 Homo sapiens Q6A162
Y2H Array
25416956
Intra DDX6 P26196 KRTAP10-8 Homo sapiens P60410
Validated Y2H
25416956
Intra DDX6 P26196 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra DDX6 P26196 KRTAP10-8 Homo sapiens P60410
Validated Y2H
32296183
Intra DDX6 P26196 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra DDX6 P26196 ZBTB14 Homo sapiens O43829
Y2H Prey Pooling
32296183
Intra DDX6 P26196 ZBTB14 Homo sapiens O43829
Y2H Array
32296183
Intra DDX6 P26196 NONO Homo sapiens Q15233-2
Y2H Prey Pooling
25416956
Intra DDX6 P26196 NONO Homo sapiens Q15233-2
Y2H Array
25416956
Intra DDX6 P26196 CNKSR3 Homo sapiens Q6P9H4
Y2H Prey Pooling
32296183
Intra DDX6 P26196 CNKSR3 Homo sapiens Q6P9H4
Validated Y2H
32296183
Intra DDX6 P26196 CNKSR3 Homo sapiens Q6P9H4
Y2H Array
32296183
Intra DDX6 P26196 SLAIN1 Homo sapiens Q8ND83
Y2H Prey Pooling
32296183
Intra DDX6 P26196 SLAIN1 Homo sapiens Q8ND83
Validated Y2H
32296183
Intra DDX6 P26196 SLAIN1 Homo sapiens Q8ND83
Y2H Array
32296183
Intra DDX6 P26196 INKA1 Homo sapiens Q96EL1
Y2H Array
32296183
Intra DDX6 P26196 INKA1 Homo sapiens Q96EL1
Y2H Prey Pooling
32296183
Intra DDX6 P26196 INKA1 Homo sapiens Q96EL1
Validated Y2H
32296183
Intra DDX6 P26196 SIPA1L2 Homo sapiens Q9P2F8-2
BFG-2H
27107012
Intra DDX6 P26196 SIPA1L2 Homo sapiens Q9P2F8-2
Y2H Array
32296183
Intra DDX6 P26196 SIPA1L2 Homo sapiens Q9P2F8-2
Validated Y2H
32296183
Intra DDX6 P26196 SIPA1L2 Homo sapiens Q9P2F8-2
Y2H Prey Pooling
32296183
Intra DDX6 P26196 SIPA1L2 Homo sapiens Q9P2F8-2
Validated Y2H
27107012
Intra DDX6 P26196 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra DDX6 P26196 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra DDX6 P26196 DES Homo sapiens P17661
Y2H Prey Pooling
32296183
Intra DDX6 P26196 DES Homo sapiens P17661
Y2H Array
32296183
Intra DDX6 P26196 REL Homo sapiens Q04864-2
Y2H Prey Pooling
32296183
Intra DDX6 P26196 REL Homo sapiens Q04864-2
Y2H Array
32296183
Intra DDX6 P26196 REL Homo sapiens Q04864-2
Validated Y2H
32296183
Intra DDX6 P26196 HOOK2 Homo sapiens Q96ED9-2
Validated Y2H
32296183
Intra DDX6 P26196 HOOK2 Homo sapiens Q96ED9-2
Y2H Array
32296183
Intra DDX6 P26196 HOOK2 Homo sapiens Q96ED9-2
Y2H Prey Pooling
32296183
Intra DDX6 P26196 FXR1 Homo sapiens P51114-2
Y2H Array
32296183
Intra DDX6 P26196 FXR1 Homo sapiens P51114-2
Y2H Prey Pooling
32296183
Intra DDX6 P26196 FXR1 Homo sapiens P51114-2
Validated Y2H
32296183
Intra DDX6 P26196 GPRASP3 Homo sapiens Q6PI77
Y2H Array
32296183
Intra DDX6 P26196 GPRASP3 Homo sapiens Q6PI77
Validated Y2H
32296183
Intra DDX6 P26196 GPRASP3 Homo sapiens Q6PI77
Y2H Prey Pooling
32296183
Intra DDX6 P26196 IKZF1 Homo sapiens Q13422-7
Validated Y2H
32296183
Intra DDX6 P26196 IKZF1 Homo sapiens Q13422-7
Y2H Array
32296183
Intra DDX6 P26196 IKZF1 Homo sapiens Q13422-7
Y2H Prey Pooling
32296183
Intra DDX6 P26196 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
30886144
Intra DDX6 P26196 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra DDX6 P26196 MTUS2 Homo sapiens Q5JR59-3
Validated Y2H
32296183
Intra DDX6 P26196 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra DDX6 P26196 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra DDX6 P26196 TLE5 Homo sapiens Q08117-2
Validated Y2H
32296183
Intra DDX6 P26196 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra DDX6 P26196 TP53BP2 Homo sapiens Q05BL1
Y2H Array
32296183
Intra DDX6 P26196 TP53BP2 Homo sapiens Q05BL1
Validated Y2H
32296183
Intra DDX6 P26196 TP53BP2 Homo sapiens Q05BL1
Y2H Prey Pooling
32296183
Intra DDX6 P26196 TCF12 Homo sapiens Q99081-3
Validated Y2H
32296183
Intra DDX6 P26196 TCF12 Homo sapiens Q99081-3
Y2H Array
32296183
Intra DDX6 P26196 TCF12 Homo sapiens Q99081-3
Y2H Prey Pooling
32296183
Intra DDX6 P26196 FCHO1 Homo sapiens A0A0C3SFZ9
Y2H Array
32296183
Intra DDX6 P26196 FCHO1 Homo sapiens A0A0C3SFZ9
Y2H Prey Pooling
32296183
Intra DDX6 P26196 DISC1 Homo sapiens Q9NRI5-2
Validated Y2H
32296183
Intra DDX6 P26196 DISC1 Homo sapiens Q9NRI5-2
Y2H Array
32296183
Intra DDX6 P26196 DISC1 Homo sapiens Q9NRI5-2
Y2H Prey Pooling
32296183
Intra DDX6 P26196 ZBTB10 Homo sapiens Q96DT7-3
Y2H Array
32296183
Intra DDX6 P26196 ZBTB10 Homo sapiens Q96DT7-3
Y2H Prey Pooling
32296183
Intra DDX6 P26196 ZBTB10 Homo sapiens Q96DT7-3
Validated Y2H
32296183
Intra DDX6 P26196 SCYL1 Homo sapiens Q96KG9-4
Y2H Prey Pooling
32296183
Intra DDX6 P26196 SCYL1 Homo sapiens Q96KG9-4
Validated Y2H
32296183
Intra DDX6 P26196 SCYL1 Homo sapiens Q96KG9-4
Y2H Array
32296183
Intra DDX6 P26196 POU6F2 Homo sapiens P78424
Y2H Prey Pooling
32296183
Intra DDX6 P26196 POU6F2 Homo sapiens P78424
Validated Y2H
32296183
Intra DDX6 P26196 POU6F2 Homo sapiens P78424
Y2H Array
32296183
Intra DDX6 P26196 CCDC14 Homo sapiens Q49A88-3
Validated Y2H
32296183
Intra DDX6 P26196 CCDC14 Homo sapiens Q49A88-3
Y2H Array
32296183
Intra DDX6 P26196 CCDC14 Homo sapiens Q49A88-3
Y2H Prey Pooling
32296183
Intra DDX6 P26196 LZTS1 Homo sapiens Q9Y250
Validated Y2H
32296183
Intra DDX6 P26196 LZTS1 Homo sapiens Q9Y250
Y2H Prey Pooling
32296183
Intra DDX6 P26196 LZTS1 Homo sapiens Q9Y250
Y2H Array
32296183
Intra DDX6 P26196 TCF4 Homo sapiens P15884-3
Y2H Prey Pooling
32296183
Intra DDX6 P26196 TCF4 Homo sapiens P15884-3
Y2H Array
32296183
Intra DDX6 P26196 ZC2HC1C Homo sapiens Q53FD0-2
Y2H Prey Pooling
32296183
Intra DDX6 P26196 ZC2HC1C Homo sapiens Q53FD0-2
Validated Y2H
32296183
Intra DDX6 P26196 ZC2HC1C Homo sapiens Q53FD0-2
Y2H Array
32296183
Intra DDX6 P26196 SPATA6 Homo sapiens Q9NWH7-2
Validated Y2H
32296183
Intra DDX6 P26196 SPATA6 Homo sapiens Q9NWH7-2
Y2H Array
32296183
Intra DDX6 P26196 SPATA6 Homo sapiens Q9NWH7-2
Y2H Prey Pooling
32296183
Intra DDX6 P26196 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra DDX6 P26196 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
32296183
Intra DDX6 P26196 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra DDX6 P26196 EFHC2 Homo sapiens Q5JST6
Y2H Prey Pooling
32296183
Intra DDX6 P26196 EFHC2 Homo sapiens Q5JST6
Y2H Array
32296183
Intra DDX6 P26196 EFHC2 Homo sapiens Q5JST6
Validated Y2H
32296183
Cross DDX6 P26196 N SARS-CoV-2 P0DTC9
Confocal
35107372
Cross DDX6 P26196 N SARS-CoV-2 P0DTC9
Anti Bait CoIP
35107372
Intra DDX6 P26196 PATL1 Homo sapiens Q86TB9
Anti Bait CoIP
20584987
Intra DDX6 P26196 PATL1 Homo sapiens Q86TB9
BN-PAGE
26184334
Intra DDX6 P26196 PATL1 Homo sapiens Q86TB9
Confocal
20584987
Intra DDX6 P26196 PATL1 Homo sapiens Q86TB9
Anti Tag CoIP
26184334
Intra DDX6 P26196 PATL1 Homo sapiens Q86TB9
Anti Tag CoIP
35271311
Intra DDX6 P26196 JAKMIP1 Homo sapiens Q96N16
Validated Y2H
32296183
Intra DDX6 P26196 JAKMIP1 Homo sapiens Q96N16
Y2H Prey Pooling
32296183
Intra DDX6 P26196 JAKMIP1 Homo sapiens Q96N16
Y2H Array
32296183
Intra DDX6 P26196 VPS52 Homo sapiens Q8N1B4
Y2H Array
32296183
Intra DDX6 P26196 VPS52 Homo sapiens Q8N1B4
Validated Y2H
25416956
Intra DDX6 P26196 VPS52 Homo sapiens Q8N1B4
Validated Y2H
32296183
Intra DDX6 P26196 VPS52 Homo sapiens Q8N1B4
Y2H Array
25416956
Intra DDX6 P26196 VPS52 Homo sapiens Q8N1B4
Y2H Prey Pooling
32296183
Intra DDX6 P26196 EIF4ENIF1 Homo sapiens Q9NRA8
Validated Y2H
32296183
Intra DDX6 P26196 EIF4ENIF1 Homo sapiens Q9NRA8
Y2H Array
25416956
Intra DDX6 P26196 EIF4ENIF1 Homo sapiens Q9NRA8
Y2H Array
32296183
Intra DDX6 P26196 EIF4ENIF1 Homo sapiens Q9NRA8
Anti Tag CoIP
26184334
Intra DDX6 P26196 EIF4ENIF1 Homo sapiens Q9NRA8
Y2H Prey Pooling
25416956
Intra DDX6 P26196 EIF4ENIF1 Homo sapiens Q9NRA8
Anti Tag CoIP
35271311
Intra DDX6 P26196 EIF4ENIF1 Homo sapiens Q9NRA8
Y2H Prey Pooling
32296183
Intra DDX6 P26196 EIF4ENIF1 Homo sapiens Q9NRA8
Validated Y2H
25416956
Intra DDX6 P26196 PDLIM7 Homo sapiens Q9NR12
Y2H Prey Pooling
32296183
Intra DDX6 P26196 PDLIM7 Homo sapiens Q9NR12
Validated Y2H
32296183
Intra DDX6 P26196 PDLIM7 Homo sapiens Q9NR12
Y2H Array
32296183
Intra DDX6 P26196 TRAF2 Homo sapiens Q12933
Validated Y2H
32296183
Intra DDX6 P26196 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra DDX6 P26196 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra DDX6 P26196 DCP1A Homo sapiens Q9NPI6
IF
16364915
Intra DDX6 P26196 DCP1A Homo sapiens Q9NPI6
Anti Tag CoIP
33961781
Intra DDX6 P26196 DCP1A Homo sapiens Q9NPI6
Anti Tag CoIP
28514442
Intra DDX6 P26196 DCP1A Homo sapiens Q9NPI6
Anti Tag CoIP
35271311
Intra DDX6 P26196 DCP1A Homo sapiens Q9NPI6
TAP
24981860
Intra DDX6 P26196 DCP1A Homo sapiens Q9NPI6
Anti Tag CoIP
16364915
Intra DDX6 P26196 BIRC7 Homo sapiens Q96CA5
Validated Y2H
25416956
Intra DDX6 P26196 BIRC7 Homo sapiens Q96CA5
Validated Y2H
32296183
Intra DDX6 P26196 BIRC7 Homo sapiens Q96CA5
Y2H Array
32296183
Intra DDX6 P26196 BIRC7 Homo sapiens Q96CA5
Y2H Prey Pooling
25416956
Intra DDX6 P26196 BIRC7 Homo sapiens Q96CA5
Y2H Prey Pooling
32296183
Intra DDX6 P26196 BIRC7 Homo sapiens Q96CA5
Y2H Array
31515488
Intra DDX6 P26196 ZRANB1 Homo sapiens Q9UGI0
Y2H Prey Pooling
32296183
Intra DDX6 P26196 ZRANB1 Homo sapiens Q9UGI0
Validated Y2H
32296183
Intra DDX6 P26196 ZRANB1 Homo sapiens Q9UGI0
Y2H Array
32296183
Intra DDX6 P26196 AGO2 Homo sapiens Q9UKV8
Anti Bait CoIP
28683311
Intra DDX6 P26196 AGO2 Homo sapiens Q9UKV8
Anti Tag CoIP
28683311
Intra DDX6 P26196 TCF4 Homo sapiens P15884
Y2H Prey Pooling
25416956
Intra DDX6 P26196 MESD Homo sapiens Q14696
Y2H Prey Pooling
32296183
Intra DDX6 P26196 MESD Homo sapiens Q14696
Validated Y2H
32296183
Intra DDX6 P26196 MESD Homo sapiens Q14696
Y2H Array
32296183
Intra DDX6 P26196 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra DDX6 P26196 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra DDX6 P26196 GOLGA2 Homo sapiens Q08379
Validated Y2H
32296183
Intra DDX6 P26196 GOLGA2 Homo sapiens Q08379
Y2H Array
25416956
Intra DDX6 P26196 ATXN2 Homo sapiens Q99700
Anti Tag CoIP
35271311
Intra DDX6 P26196 ATXN2 Homo sapiens Q99700
TAP
24981860
Intra DDX6 P26196 ATXN2 Homo sapiens Q99700
Y2H
17392519
Intra DDX6 P26196 ATXN2 Homo sapiens Q99700
Anti Tag CoIP
26184334
Intra DDX6 P26196 ATXN2 Homo sapiens Q99700
Anti Tag CoIP
33961781
Intra DDX6 P26196 ATXN2 Homo sapiens Q99700
Confocal
17392519
Intra DDX6 P26196 ATXN2 Homo sapiens Q99700
Anti Bait CoIP
17392519
Intra DDX6 P26196 JUP Homo sapiens P14923
Y2H Prey Pooling
32296183
Intra DDX6 P26196 JUP Homo sapiens P14923
Y2H Array
32296183
Intra DDX6 P26196 IK Homo sapiens Q13123
Y2H Prey Pooling
32296183
Intra DDX6 P26196 IK Homo sapiens Q13123
Validated Y2H
32296183
Intra DDX6 P26196 IK Homo sapiens Q13123
Y2H Array
32296183
Intra DDX6 P26196 SHMT1 Homo sapiens P34896
Y2H Prey Pooling
32296183
Intra DDX6 P26196 SHMT1 Homo sapiens P34896
Validated Y2H
32296183
Intra DDX6 P26196 SHMT1 Homo sapiens P34896
Y2H Array
32296183
Intra DDX6 P26196 MAGED1 Homo sapiens Q9Y5V3
Validated Y2H
32296183
Intra DDX6 P26196 MAGED1 Homo sapiens Q9Y5V3
Y2H Prey Pooling
32296183
Intra DDX6 P26196 MAGED1 Homo sapiens Q9Y5V3
Y2H Array
32296183
Intra DDX6 P26196 TLE5 Homo sapiens Q08117
Y2H Array
25416956
Intra DDX6 P26196 TLE5 Homo sapiens Q08117
Validated Y2H
25416956
Intra DDX6 P26196 TRIM27 Homo sapiens P14373
Validated Y2H
25416956
Intra DDX6 P26196 TRIM27 Homo sapiens P14373
Y2H Array
25416956
Intra DDX6 P26196 TRIM27 Homo sapiens P14373
Y2H Array
32296183
Intra DDX6 P26196 TRIM27 Homo sapiens P14373
Y2H Prey Pooling
25416956
Intra DDX6 P26196 TRIM27 Homo sapiens P14373
Y2H Prey Pooling
32296183
Intra DDX6 P26196 CALCOCO2 Homo sapiens Q13137
Y2H Array
32296183
Intra DDX6 P26196 CALCOCO2 Homo sapiens Q13137
Y2H Prey Pooling
32296183
Intra DDX6 P26196 CALCOCO2 Homo sapiens Q13137
Validated Y2H
25416956
Intra DDX6 P26196 CALCOCO2 Homo sapiens Q13137
Validated Y2H
32296183
Intra DDX6 P26196 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra DDX6 P26196 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
32296183
Intra DDX6 P26196 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra DDX6 P26196 ZBTB43 Homo sapiens O43298
Y2H Array
32296183
Intra DDX6 P26196 ZBTB43 Homo sapiens O43298
Y2H Prey Pooling
32296183
Intra DDX6 P26196 SORBS3 Homo sapiens O60504
Y2H Prey Pooling
32296183
Intra DDX6 P26196 SORBS3 Homo sapiens O60504
Y2H Array
32296183
Intra DDX6 P26196 RBM11 Homo sapiens P57052
Validated Y2H
32296183
Intra DDX6 P26196 RBM11 Homo sapiens P57052
Y2H Prey Pooling
32296183
Intra DDX6 P26196 RBM11 Homo sapiens P57052
Y2H Array
32296183
Intra DDX6 P26196 TRIM37 Homo sapiens O94972
Validated Y2H
25416956
Intra DDX6 P26196 PAK5 Homo sapiens Q9P286
Y2H Prey Pooling
32296183
Intra DDX6 P26196 PAK5 Homo sapiens Q9P286
Validated Y2H
32296183
Intra DDX6 P26196 PAK5 Homo sapiens Q9P286
Y2H Array
32296183
Intra DDX6 P26196 BEGAIN Homo sapiens Q9BUH8
Y2H Array
32296183
Intra DDX6 P26196 BEGAIN Homo sapiens Q9BUH8
Y2H Prey Pooling
32296183
Intra DDX6 P26196 BEGAIN Homo sapiens Q9BUH8
Validated Y2H
32296183
Intra DDX6 P26196 ZBTB8A Homo sapiens Q96BR9
Y2H Prey Pooling
32296183
Intra DDX6 P26196 ZBTB8A Homo sapiens Q96BR9
Y2H Prey Pooling
25416956
Intra DDX6 P26196 ZBTB8A Homo sapiens Q96BR9
Validated Y2H
32296183
Intra DDX6 P26196 ZBTB8A Homo sapiens Q96BR9
Y2H Array
25416956
Intra DDX6 P26196 ZBTB8A Homo sapiens Q96BR9
Y2H Array
32296183
Intra DDX6 P26196 CEP76 Homo sapiens Q8TAP6
Validated Y2H
32296183
Intra DDX6 P26196 CEP76 Homo sapiens Q8TAP6
Y2H Prey Pooling
32296183
Intra DDX6 P26196 CEP76 Homo sapiens Q8TAP6
Y2H Array
32296183
Intra DDX6 P26196 IKZF1 Homo sapiens Q13422
Y2H Array
25416956
Intra DDX6 P26196 IKZF1 Homo sapiens Q13422
Y2H Prey Pooling
25416956
Intra DDX6 P26196 DDX17 Homo sapiens Q92841
Y2H Prey Pooling
32296183
Intra DDX6 P26196 DDX17 Homo sapiens Q92841
Validated Y2H
32296183
Intra DDX6 P26196 DDX17 Homo sapiens Q92841
Y2H Array
32296183
Intra DDX6 P26196 DDX17 Homo sapiens Q92841
Anti Tag CoIP
26184334
Intra DDX6 P26196 RUNDC3A Homo sapiens Q59EK9
Y2H Array
25416956
Intra DDX6 P26196 RUNDC3A Homo sapiens Q59EK9
Y2H Prey Pooling
25416956
Intra DDX6 P26196 PRPH Homo sapiens P41219
Validated Y2H
32296183
Intra DDX6 P26196 PRPH Homo sapiens P41219
Y2H Array
32296183
Intra DDX6 P26196 PRPH Homo sapiens P41219
Y2H Prey Pooling
32296183
Intra DDX6 P26196 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra DDX6 P26196 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra DDX6 P26196 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra DDX6 P26196 USH1G Homo sapiens Q495M9
Y2H Prey Pooling
32296183
Intra DDX6 P26196 USH1G Homo sapiens Q495M9
Validated Y2H
32296183
Intra DDX6 P26196 USH1G Homo sapiens Q495M9
Y2H Array
32296183
Intra DDX6 P26196 NAB2 Homo sapiens Q15742
Y2H Array
32296183
Intra DDX6 P26196 NAB2 Homo sapiens Q15742
Y2H Prey Pooling
32296183
Intra DDX6 P26196 NAB2 Homo sapiens Q15742
Validated Y2H
32296183
Intra DDX6 P26196 DNAAF11 Homo sapiens Q86X45
Validated Y2H
32296183
Intra DDX6 P26196 DNAAF11 Homo sapiens Q86X45
Y2H Array
32296183
Intra DDX6 P26196 DNAAF11 Homo sapiens Q86X45
Y2H Prey Pooling
32296183
Intra DDX6 P26196 GIGYF1 Homo sapiens O75420
Y2H Prey Pooling
32296183
Intra DDX6 P26196 GIGYF1 Homo sapiens O75420
Y2H Array
32296183
Intra DDX6 P26196 EDC3 Homo sapiens Q96F86
Validated Y2H
32296183
Intra DDX6 P26196 EDC3 Homo sapiens Q96F86
Anti Tag CoIP
33961781
Intra DDX6 P26196 EDC3 Homo sapiens Q96F86
Y2H Array
32296183
Intra DDX6 P26196 EDC3 Homo sapiens Q96F86
Anti Tag CoIP
28514442
Intra DDX6 P26196 EDC3 Homo sapiens Q96F86
TAP
24981860
Intra DDX6 P26196 EDC3 Homo sapiens Q96F86
Y2H Array
29892012
Intra DDX6 P26196 EDC3 Homo sapiens Q96F86
BN-PAGE
26184334
Intra DDX6 P26196 EDC3 Homo sapiens Q96F86
Anti Tag CoIP
35271311
Intra DDX6 P26196 EDC3 Homo sapiens Q96F86
Y2H Array
31515488
Intra DDX6 P26196 EDC3 Homo sapiens Q96F86
Validated Y2H
25416956
Intra DDX6 P26196 EDC3 Homo sapiens Q96F86
Y2H Prey Pooling
32296183
Intra DDX6 P26196 EDC3 Homo sapiens Q96F86
Anti Tag CoIP
26184334
Intra DDX6 P26196 EDC3 Homo sapiens Q96F86
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Intellectual Developmental Disorder With Impaired Language And Dysmorphic Facies

IDDILF
Non-Specific Syndromic Intellectual Disability

Complex Neurodevelopmental Disorder
Telecanthus
Childhood Liposarcoma

Pediatric Liposarcoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03663 DDX6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus DDX6 MGD MGI:104976
Bos taurus DDX6 VGNC VGNC:27981
Canis familiaris DDX6 VGNC VGNC:39869
Felis catus DDX6 VGNC VGNC:61420
Macaca mulatta DDX6 VGNC VGNC:71764
Rattus norvegicus DDX6 RGD RGD:1564560