1. Gene
  2. Hdac8 - histone deacetylase 8 Gene

Hdac8 - histone deacetylase 8 Gene

Mus musculus

Also known as 2610007D20Rik

Gene ID: 70315 | Gene type: protein coding

About Hdac8

Chromosome X: 101,328,245-101,548,965 reverse strand.GRCm39:CM001013.3

This gene has 5 transcripts (splice variants), 202 orthologues, 10 paralogues and is associated with 18 phenotypes. Ubiquitous expression in cerebellum adult (RPKM 1.2), bladder adult (RPKM 1.) and 28 other tissues.

Summary

Predicted to enable chromatin binding activity; heat shock protein binding activity; and histone deacetylase activity. Predicted to be involved in several processes, including histone deacetylation; negative regulation of macromolecule metabolic process; and regulation of chromosome organization. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of histone deacetylase complex. Is expressed in several structures, including 2-cell stage embryo; brain; embryo ectoderm; foregut; and retina. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 5 and Wilson-Turner syndrome. Orthologous to human HDAC8 (histone deacetylase 8). [provided by Alliance of Genome Resources, Apr 2022]

Hdac8 Products(2)

mRNA Protein Name
NM_027382.4 NP_081658.1 histone deacetylase 8 isoform 1
NM_001313742.1 NP_001300671.1 histone deacetylase 8 isoform 2

Hdac8 Protein Structure

HDAC8

HDAC8: cd10000 (15 - 376)

  • 0
  • 100
  • 200
  • 300
  • 377 a.a.
Protein Preferred Names Protein Names

histone deacetylase 8

HD8

protein deacetylase HDAC8

protein decrotonylase HDAC8

Recombinant Hdac8 Proteins

Cat. No. Product Name Accession Purity
HY-P75144 HDAC8 Protein, Mouse (sf9, His) Q8VH37-1 (M1-V377) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens Hdac8 NCBI NCBI:55869