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Results for "

DAG lipase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ATGL (3) DAGL (8) Lipase (4) MAGL (28) Acyltransferase (1) Androgen Receptor (1) Apoptosis (6) Autophagy (2) Bacterial (7) Beta-lactamase (1) Biochemical Assay Reagents (11) Calcium Channel (1) Cannabinoid Receptor (2) Carboxylesterase (2) Cholinesterase (ChE) (1) COX (1) Drug Metabolite (1) Endogenous Metabolite (29) FAAH (6) Fatty Acid Synthase (FASN) (3) Fluorescent Dye (7) Fungal (7) Glucosidase (1) HCV (3) Histamine Receptor (1) Isotope-Labeled Compounds (4) Liposome (1) LPL Receptor (1) mAChR (1) Melanocortin Receptor (2) MetAP (1) MMP (1) Phospholipase (4) PKC (3) Small Interfering RNA (siRNA) (1) TRP Channel (3) Wnt (1)
By Research Areas:	Cancer (21) Cardiovascular Disease (3) Endocrinology (3) Infection (14) Inflammation/Immunology (17) Metabolic Disease (66) Neurological Disease (26)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Pre-designed siRNA Sets (1) Emulsifiers (1) Solubilizing Agents (1) siRNAs (1)

178

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: Lipase DAGL MAGL ATGL

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-144809

*Pancreatic lipase/Carboxylesterase 1-IN-1*	Carboxylesterase	Metabolic Disease
Pancreatic lipase/Carboxylesterase 1-IN-1 (Compound 39) is a potent dual inhibitor of *pancreatic lipase* (PL) and human carboxylesterase 1A (hCES1A) with IC₅₀** values of 2.13 µM and 0.055 µM against PL and hCES1A .

HY-Y1422

Triacylglycerol lipase Alkaline lipase	Others	Metabolic Disease
Triacylglycerol lipase is an enzyme that preferentially hydrolyzes the outer links of triacylglycerols and acts only on the water-lipid interface. Pancreatic triacylglycerol lipase is the single most important determinant of lipid absorption .

HY-157313

*Pancreatic lipase-IN-1*	Others	Metabolic Disease
Pancreatic lipase-IN-1 (compound 8) ia a pancreatic lipase inhibitor with the K_i of 1.288 ?μM .

HY-144375

*Monoacylglycerol lipase* inhibitor 1**	MAGL	Others
Monoacylglycerol lipase inhibitor 1 is a potent monoacylglycerol lipase inhibitor (compound 13) .

HY-Y1422B

Lipase (MS grade)	Endogenous Metabolite	Metabolic Disease
Lipase (MS grade) catalyzes the hydrolysis of triacylglycerols to release long-chain fatty acids in a site-specific manner.

HY-143691

MGlc-DAG	Liposome	Others
MGlc-DAG, a glycoglycerolipid, can be used for the synthesis of drug delivery compound .

HY-Y1422A

Lipase, Human Pancreas Pancreatic Triacylglycerol lipase, PL, PTL, Pancreatic lipase	Others	Others
Lipase, Human Pancreas (Pancreatic Triacylglycerol Lipase, PL, PTL, Pancreatic Lipase) is a biological material or organic compound that can be used in life science research .

HY-138653

Lipase Substrate	Others	Metabolic Disease
Lipase Substrate is a substrate of lipase to detect activity .

HY-RS03519

DAG1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
DAG1 Human Pre-designed siRNA Set A contains three designed siRNAs for DAG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

DAG1 Human Pre-designed siRNA Set A DAG1 Human Pre-designed siRNA Set A

HY-Y1422D

Lipase 435	Others	Others
Lipase 435, an immobilized lipase derived from Candida antarctica fraction B, shows extensive industrial application in producing enantiopure pharmaceuticals, functional lipids, biodiesel, etc. .

HY-Y1422H

Lipase AYS	Others	Others
Lipase AYS is an immobilized lipase derived from Candida rugosa .

HY-Y1422K

Lipase PS-IM	Others	Others
Lipase PS-IM is an immobilized lipase derived from Burkholderiacepacia .

HY-E70307

Lipase, Porcine Pancreas	Endogenous Metabolite	Others
Lipase, Porcine Pancreas (PPL) is a porcine pancreas lipase that catalyzes the hydrolysis of mustard oil. The catalytic activity of Lipase, Porcine Pancreas may also be affected by surfactants such as Span, Tween and Triton. For example, 0.02 M sorbose monooleate (Span 80), 0.01 M Tween 80, and 0.01 M Triton X-100 inhibited Lipase and Porcine Pancreas free lipase catalytic rates to 75%, 84%, and 93% respectively .

HY-112911

*Endothelial lipase* inhibitor-1**	Others	Cardiovascular Disease
Endothelial lipase inhibitor-1 is a potent endothelial lipase inhibitor with an IC₅₀ of 49 nM.

HY-Y1422E

Lipase AS	Others	Others
Lipase AS comes from Aspergillusniger and can be used for catalyzing chemical reactions.

HY-Y1422C

Lipase, Chromobacterium viscosum	Endogenous Metabolite	Others
Lipase, Chromobacterium viscosum catalyzes the hydrolysis of ester bonds in lipids into glycerol and fatty acids. Lipase, Chromobacterium viscosum is involved in the digestion of fats and can be used industrially for the production of flavors, pharmaceuticals, and biodiesel .

HY-157534

*Pancreatic lipase-IN-2*	Others	Metabolic Disease
Pancreatic lipase-IN-2 (compound 7r) is a potent inhibitor of pancreatic lipase (PL), with the IC₅₀ value of 2.67 μM, that has anti-obesity effect .

HY-P2752

*Lipoprotein lipase, Pseudomonas sp* LPL	Endogenous Metabolite	Metabolic Disease Cancer
Lipoprotein lipase, Pseudomonas sp (LPL) is a multifunctional enzyme from adipose tissue, heart and skeletal muscle, islets and macrophages. Lipoprotein lipase promotes normal lipoprotein metabolism, delivery and utilization of tissue-specific substrates. Lipoprotein lipase catalyzes the rate-limiting step of lipids in blood circulation .

HY-Y1422J

Lipase PS-SD	Others	Others
Lipase PS-SD comes from Burkholderiacepacia and can be used for catalytic reaction .

HY-Y1422I

Lipase AK	Others	Others
Lipase AK comes from Pseudomonas fluorescens and shows good applicability in ester synthesis of food industry, the biofuel synthesis, the synthesis of enantiomeric pure chiral drugs and so on .

HY-117095

4-Methylumbelliferyl oleate	Fluorescent Dye	Metabolic Disease
4-Methylumbelliferyl oleate is a fluorogenic substrate for acid and alkaline *lipases. 4-Methylumbelliferyl oleate is cleaved by lipases*, liberating 4-Methylumbelliferyl (Ex/Em=320/450 nm) .

HY-158362A

*Monoglyceride lipase, Bacillus sp.*	Endogenous Metabolite	Neurological Disease Metabolic Disease Inflammation/Immunology
Monoglyceride lipase, Bacillus sp., is a key enzyme involved in lipid metabolism. It catalyzes the hydrolysis of monoglycerides (particularly 2-AG, or 2-arachidonoylglycerol) into glycerol and free fatty acids. By regulating the levels of 2-AG, Monoglyceride lipase, Bacillus sp., can influence neural signaling, pain perception, inflammatory responses, and metabolic processes .

HY-E70311

TLL-10X Thermomyces lanuginosus lipase	Endogenous Metabolite	Others
TLL-10X (Thermomyces lanuginosus lipase) is a high-efficiency biocatalyst, a lipase from Thermomyces lanuginosus. TLL-10X can be conjugated to magnetic nanoparticles and coupled to the surface of Fe(3)O(4)-COOH to obtain better temperature resistance and pH resistance. The activity unit (U) of lipase is defined as the amount of enzyme that produces 1 μmol of fatty acid per minute under experimental conditions .

HY-112552

1,2-Distearoyl-sn-glycerol DSG; 1,2-Dioctadecanoyl-sn-glycerol	Endogenous Metabolite	Others
1,2-Distearoyl-sn-glycerol (DSG; 1,2-Dioctadecanoyl-sn-glycerol) acts as an internal standard for Separation and identification of molecular species of 1,2-diacyl-sn-glycerol (DAG) .

HY-N12294

Ciwujianoside D2	Others	Metabolic Disease
Ciwujianoside D2, a saponin compound, can enhance pancreatic lipase activity in vitro .

HY-N12296

Ciwujianoside C4	Others	Metabolic Disease
Ciwujianoside C4, a saponin compound, can enhance pancreatic lipase activity in vitro .

HY-E70313

CalB-10X Candida antarctica lipase B	Endogenous Metabolite	Others
CalB-10X, Candida antarctica lipase B (CALB), catalyzes polymer synthesis .

HY-E70310

BD-10X lipase for biodiesel production	Endogenous Metabolite	Others
BD-10X (Lipase for biodiesel production) is a methanol-resistant lipase with high catalytic activity and can be used for the production of biodiesel. The reaction conditions of BD-10X are mild, which can avoid the oxidation of hydroxyl groups and the opening of double bonds, and prevent the production of by-products other than glycerol .

HY-E70332

Lipase, Aspergillus niger	Endogenous Metabolite	Others
Lipase, Aspergillus niger is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-118442

Sphingosine (d14:1) Tetradecasphing-4-enine	PKC	Cancer
Sphingosine (d14:1) (Tetradecasphing-4-enine), a sphingolipid, is a potent Protein kinase C (PKC) inhibitor. Sphingosine (d14:1) prevents its interaction with sn-1,2-diacylglycerol (DAG)/Phorbol esters .

HY-N12297

Ciwujianoside C2	Others	Others
Ciwujianoside C2 is a saponin, that can be isolated from the leaves of Acanthopanax senticosus. Ciwujianoside C2 enhances pancreatic lipase activity in vitro .

HY-136562

N-Arachidonyl maleimide	MAGL	Metabolic Disease
N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC₅₀ value of 140 nM .

HY-N12292

Acanthopanaxoside A	Others	Metabolic Disease
Acanthopanaxoside A, a triterpenoid saponin, has pancreatic *lipase* inhibitory action .

HY-168032

MAGL-IN-18	MAGL	Inflammation/Immunology
MAGL-IN-18 (compound 118) is a potent *Monoacylglycerol lipase* (MAGL) inhibitor with an IC₅₀** of 0.03 nM .

HY-116583

Resorufin butyrate	Cholinesterase (ChE)	Metabolic Disease
Resorufin butyrate is a fluorogenic substrate for triglyceride lipases and cholinesterase (Ex=570 nm, Em=580 nm) .

HY-121517

URB754	Others	Neurological Disease
URB754 is a potent inhibitor of the endocannabinoid-deactivating enzyme monoacylglycerol lipase (MGL) with an IC₅₀ of 200 nM .

HY-153523

Hi 76-0079 NNC0076-0079; 76-0079	Others	Metabolic Disease
Hi 76-0079 (Compound 31) is a hormone-sensitive lipase (HSL) inhibitor with an IC₅₀ of 184 nM .

HY-E70277

Hexadecyl-CoA	ATGL	Metabolic Disease
Hexadecyl-CoA is a thioether analog of acyl-CoA that can inhibit adipose triglyceride lipase (ATGL) .

HY-N8362

1-Isomangostin	Others	Metabolic Disease
1-Isomangostin is an inhibitor of pancreatic lipase. 1-Isomangostin inhibits porcine pancreatic lipase with an IC₅₀ of 34.5 μM. 1-Isomangostin has anti-obesity activity .

HY-N12298

Ciwujianoside C1	Others	Others
Ciwujianoside C1 is a saponin, that can be isolated from the leaves of Acanthopanax senticosus. Ciwujianoside C1 inhibits pancreatic lipase activity in vitro .

HY-14471

Cetilistat ATL-962	Others	Metabolic Disease
Cetilistat (ATL-962), an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC₅₀s of 54.8 nM, and 5.95 nM, respectively .

HY-136124

Cetilistat impurity 1	Drug Metabolite	Others
Cetilistat impurity 1 is an impurity of Cetilistat. Cetilistat, an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC₅₀s of 54.8 nM, and 5.95 nM, respectively .

HY-126938

4-Methylumbelliferyl heptanoate	Others	Others
4-Methylumbelliferyl heptanoate is a potent fluorometric substrate of lipase .

HY-E70312

CalB-10Xup Candida antarctica lipase	Endogenous Metabolite	Others
CalB-10Xup (Candida antarctica lipase) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .

HY-118653

SAR629	MAGL	Metabolic Disease
SAR629 is a potent *monoglyceride lipase* (MGL)** covalent inhibitor. SAR629 also inhibits 2-Arachidonoylglycerol (2-AG) degradation .

HY-14471R

Cetilistat (Standard)	Others	Metabolic Disease
Cetilistat (Standard) is the analytical standard of Cetilistat. This product is intended for research and analytical applications. Cetilistat (ATL-962), an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC50s of 54.8 nM, and 5.95 nM, respectively .

HY-131897

1-Stearoyl-2-arachidonoyl-sn-glycerol 1 Publications Verification	PKC TRP Channel Endogenous Metabolite	Neurological Disease
1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity .

HY-W099648

4-Methylumbelliferyl octanoate	Others	Others
4-Methylumbelliferyl octanoate is a octoate. 4-Methylumbelliferyl octanoate can be used as a s ubstrate of hog pancreatic lipase .

HY-123012A

Lubabegron fumarate LY-591281; LY-488756 fumarate	Androgen Receptor	Metabolic Disease
Lubabegron (LY-488756) fumarate is an antagonist of the adrenergic receptor (β-AR). Lubabegron fumarate can antagonize the stimulatory effects of β1-AR and β2-AR agonists on lipase respectively .

HY-131999

3,4,5-Trihydroxycinnamic acid decyl ester	Others	Metabolic Disease
3,4,5-Trihydroxycinnamic acid decyl ester is an excellent inhibitor of lipid absorption and accumulation, with anti-obesity properties. 3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor, with an EC₅₀ of approximately 0.9 μM .

Cat. No.	Product Name	Type

HY-116583

Resorufin butyrate	Fluorescent Dyes/Probes
Resorufin butyrate is a fluorogenic substrate for triglyceride lipases and cholinesterase (Ex=570 nm, Em=580 nm) .

HY-W010947

4-Methylumbelliferyl palmitate

Fluorescent Dyes/Probes

4-Methylumbelliferyl palmitate is an excellent fluorophore for measuring acid lipase in human leukocytes. Acidity and solvent have important influence on its fluorescence. 4-Methylumbelliferyl palmitate exists mainly as neutral molecular form which can be produced strong fluorescence at 445 nm in near neutral aqueous solutions, and exist mainly as anion form which can be produced stronger fluorescence at 445 nm in weak alkaline solutions .

HY-114879

DDAO 1 Publications Verification	Fluorescent Dyes/Probes
DDAO is a promising near-infrared (NIR) red fluorescent probewith tunable excitation wavelength (600-650nm) and longemission wavelength(λem=656nm). DDAO can de desiged for detection of the activities of different enzymes such asβ-galactosidase,sulfatase, proteinphosphatase2A,carboxylesterase 2, humanalbumin andesterases .

HY-D0047

5-CFDA 3 Publications Verification 5-Carboxyfluorescein diacetate	Fluorescent Dyes/Probes
5-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .

HY-D0721

6-CFDA 6-Carboxyfluorescein diacetate	Fluorescent Dyes/Probes
6-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .

HY-D0722

5(6)-CFDA 5 Publications Verification 5-(6)-Carboxyfluorescein diacetate; CFDA	Fluorescent Dyes/Probes
5(6)-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes .

HY-W013168

4-Nitrophenyl palmitate

4-Nitrophenyl hexadecanoate; p-Nitrophenyl Palmitate; pNpp

Dyes

4-Nitrophenyl palmitate (4-Nitrophenyl hexadecanoate; p-Nitrophenyl Palmitate) is a colorimetric lipase and esterase substrate. Upon enzymatic hydrolysis of 4-Nitrophenyl palmitate, 4-nitrophenol is released, which can be quantified by colorimetric detection at 410 nm as a measure of enzyme activity. 4-Nitrophenyl palmitate has been used to characterize the activity of various bacterial and mammalian enzymes, including Burkholderia and porcine pancreatic lipase.

HY-150978

DDAO-C6	Fluorescent Dyes/Probes
DDAO-C6 is a cridone ester derivative, highly specific fluorescence for detecting human serum albumin (HSA). DDAO-C6 acts as an enzymatic activatable near-infrared fluorescent probe in visually sensing endogenous lipase from gut microbes (Ex/Em=600/658 nm) .

Cat. No.	Product Name	Type

HY-W127409

1,2-Dimyristoyl-rac-glycerol

Drug Delivery

1,2-Dimyristoyl-rac-glycerol (C14:0) is a carboxylic acid ester, glycerolipid and diglyceride with an additional myristoyl group that facilitates interactions between proteins and lipids. Can be used as detergent or reagent. It plays a role in cell biology experiments involving the metabolism and metabolic pathways of glycerolipids. As a diglyceride, this substance consists of two fatty acid chains covalently bonded in the 1,2-form to a glycerol molecule. The diglyceride (DAG) study investigated the process by which DAG is depleted to inhibit fat accumulation. Reagent grade, for research use only.

HY-W099563

4-Nitrophenyl stearate

Enzyme Substrates

4-Nitrophenyl stearate, which is an ester formed by the condensation of stearic acid and 4-nitrophenol, is commonly used as a substrate for enzymatic assays, where the hydrolysis of ester bonds by esterase and lipase can be measured by absorbance or ratio In addition, 4-Nitrophenyl stearate has been used as a model compound to study the enzymatic activity and selectivity of lipases and esterases from various sources. The long hydrophobic tail of the molecule makes it suitable for use in lipophilic Good solubility in the environment makes it a useful probe for studying lipid metabolism.

HY-W127391

1,2-Dilaurin

(Rac)-1,2-Didodecanoylglycerol

Drug Delivery

1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).

HY-D1005

Poloxamer 407 (F127) 2 Publications Verification PEG-PPG-PEG, 12600 (Average Mn)	Co-solvents
Poloxamer 407 (F127) is a nonionic surfactant that is 100% active and relatively non-toxic to cells at low concentrations, and frequently used with dye AM esters such as Indo-1 AM, Fura-2 AM, Calcein AM, Fluo-3 AM, Fluo-4 AM, Quest Fluo-8? AM and Quest Rhod-4? AM, etc. to improve their water solubility. Poloxamer 407 is also a lipoprotein lipase inhibitor .

HY-143691

MGlc-DAG	Drug Delivery
MGlc-DAG, a glycoglycerolipid, can be used for the synthesis of drug delivery compound .

HY-W100403

Choline tosylate Choline p-toluenesulfonate	Enzyme Substrates
Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C. Choline tosylate inhibits tumor growth in mice by inhibiting the formation of diacylglycerol (DAG) .

HY-W283889

Blue caprate	Cell Assay Reagents
Blue caprate is a chromogenic enzyme substrate typically used to detect lipase activity. It is hydrolyzed by lipase to produce a blue-purple product (biosynth: EB04034).

HY-117115

1,2-Dihexanoyl-sn-glycerol	Drug Delivery
1,2-Dihexanoyl-sn-glycerol is an analog of protein kinase C (PKC) that activates the second messenger diacylglycerol (DAG). Although the biological activity of 1,2-dicaproyl-sn-glycerol has not been well characterized, it is expected to behave similarly to 1,2-dioctanoyl-sn-glycerol.

HY-W145699

D-myo-Inositol 4-monophosphate

Biochemical Assay Reagents

D-myo-Inositol 4-mono-phosphate, also known as IMP, is a phosphorylated form of inositol that is commonly found in various metabolic pathways, especially in the biosynthesis of phospholipids and cell signaling molecules. D-myo-Inositol 4-mono-phosphate has unique chemical properties that make it an important intermediate in the production of second messengers, such as inositol triphosphate (IP3) and diacylglycerol (DAG), which signal in cells plays a key role in. D-myo-Inositol 4-mono-phosphate is also used in dietary supplements and pharmaceuticals because of its potential health benefits, including improved insulin sensitivity and cognitive function.

HY-167810

1,3-Dipentadecanoin(C15:0)	Drug Delivery
1,3-Dipentadecanoin(C15:0) is a long-chain triglyceride with substrate activity for lipid metabolism studies. 1,3-Dipentadecanoin(C15:0) is used as a model compound for studying the hydrolysis of triglycerides by lipase. 1,3-Dipentadecanoin(C15:0) can help understand the metabolic mechanism of triglycerides in chemical research.

HY-W014449

4-Nitrophenyl butyrate

Enzyme Substrates

4-Nitrophenyl butyrate consists of butyric acid chains esterified with 4-nitrophenol groups, thus giving it a yellow color. This compound is commonly used as a substrate in enzyme assays to measure esterase and lipase activity. When these enzymes cleave the ester bond, the nitrophenol group is released and the color changes from yellow to orange. Thus, the rate of color change can be used to determine enzyme activity. In addition, 4-Nitrophenyl butyrate can also be used as organic synthesis reagent and dye intermediate.

HY-121892

(Z)-KC02

Drug Delivery

(Z)-KC02 is an inhibitor of ABHD16A, the phosphatidylserine (PS) lipase that produces lyso-PS. Lysophosphatidylserine (lyso-PS) is a signaling lipid that regulates immune and neurological processes. It is associated with several neurological disorders such as retinitis pigmentosa and cataracts (PHARC). (Z)-KC02 depletes lyso-PS in lymphoblasts from PHARC subjects. (Z)-KC02 also reduces lyso-PS and lipopolysaccharide-induced cytokine production in macrophages and modulates lyso-PS metabolism in vivo .

Cat. No.	Product Name	Target	Research Area

HY-P3377

Rimtoregtide	Peptides	Inflammation/Immunology
Rimtoregtide is a polypeptide compound which significantly reduces the increase in the levels of amylase and lipase in the blood caused by acute pancreatitis. Rimtoregtide has the potential for the research of pancreatitis and acute pancreatitis (extracted from patent WO2018205233A1).

HY-P1210A

Lys-γ3-MSH(human) TFA	Melanocortin Receptor	Endocrinology
Lys-γ3-MSH(human) TFA is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) TFA potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) TFA is a potent stimulator of lipolysis with an apparent EC₅₀ of 3.56 nM. Lys-γ3-MSH(human) TFA can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .

HY-P10557

DAG peptide	Peptides	Neurological Disease
DAG peptide is a cyclic peptide. DAG peptide selectively recognizes a subset of astrocytes that are activated in Alzheimer's disease (AD) starting at an early stage of the disease. DAG peptide can be used as a tool to enhance the delivery of therapeutics and imaging agents to sites of vascular changes and astrogliosis in diseases associated with neuroinflammation .

HY-P1210

Lys-γ3-MSH(human)	Melanocortin Receptor	Endocrinology
Lys-γ3-MSH(human) is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (ACTH). Lys-γ3-MSH(human) is a potent stimulator of lipolysis with an apparent EC₅₀ of 3.56 nM. Lys-γ3-MSH(human) can activate hormone sensitive lipase (HSL) and Perilipin A resulting in lipolysis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P2752

*Lipoprotein lipase, Pseudomonas sp* LPL	Classification of Application Fields Disease Research Fields Cancer	Endogenous Metabolite
Lipoprotein lipase, Pseudomonas sp (LPL) is a multifunctional enzyme from adipose tissue, heart and skeletal muscle, islets and macrophages. Lipoprotein lipase promotes normal lipoprotein metabolism, delivery and utilization of tissue-specific substrates. Lipoprotein lipase catalyzes the rate-limiting step of lipids in blood circulation .

HY-112552

1,2-Distearoyl-sn-glycerol DSG; 1,2-Dioctadecanoyl-sn-glycerol	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1,2-Distearoyl-sn-glycerol (DSG; 1,2-Dioctadecanoyl-sn-glycerol) acts as an internal standard for Separation and identification of molecular species of 1,2-diacyl-sn-glycerol (DAG) .

HY-118442

Sphingosine (d14:1) Tetradecasphing-4-enine	Natural Products Animals Classification of Application Fields Source classification Disease Research Fields Cancer	PKC
Sphingosine (d14:1) (Tetradecasphing-4-enine), a sphingolipid, is a potent Protein kinase C (PKC) inhibitor. Sphingosine (d14:1) prevents its interaction with sn-1,2-diacylglycerol (DAG)/Phorbol esters .

HY-131897

1-Stearoyl-2-arachidonoyl-sn-glycerol 1 Publications Verification	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	PKC TRP Channel Endogenous Metabolite
1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity .

HY-N12294

Ciwujianoside D2	Triterpenes Structural Classification Polysaccharides Terpenoids Source classification Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Saccharides Araliaceae	Others
Ciwujianoside D2, a saponin compound, can enhance pancreatic lipase activity in vitro .

HY-N12296

Ciwujianoside C4	Triterpenes Structural Classification Polysaccharides Terpenoids Source classification Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Saccharides Araliaceae	Others
Ciwujianoside C4, a saponin compound, can enhance pancreatic lipase activity in vitro .

HY-N12297

Ciwujianoside C2	Triterpenes Structural Classification Polysaccharides Terpenoids Source classification Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Saccharides Araliaceae	Others
Ciwujianoside C2 is a saponin, that can be isolated from the leaves of Acanthopanax senticosus. Ciwujianoside C2 enhances pancreatic lipase activity in vitro .

HY-N12292

Acanthopanaxoside A	Triterpenes Structural Classification Polysaccharides Terpenoids Source classification Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Saccharides Araliaceae	Others
Acanthopanaxoside A, a triterpenoid saponin, has pancreatic *lipase* inhibitory action .

HY-N8362

1-Isomangostin	Structural Classification Natural Products Source classification Guttiferae Garcinia mangostana Linn. Plants	Others
1-Isomangostin is an inhibitor of pancreatic lipase. 1-Isomangostin inhibits porcine pancreatic lipase with an IC₅₀ of 34.5 μM. 1-Isomangostin has anti-obesity activity .

HY-N12298

Ciwujianoside C1	Triterpenes Structural Classification Polysaccharides Terpenoids Source classification Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Saccharides Araliaceae	Others
Ciwujianoside C1 is a saponin, that can be isolated from the leaves of Acanthopanax senticosus. Ciwujianoside C1 inhibits pancreatic lipase activity in vitro .

HY-N10606

Uvagrandol	Natural Products Uvaria grandiflora Roxb. Plants Annonaceae	Glucosidase
Uvagrandol potently inhibits α-glucosidase and porcine lipase (IC₅₀: 15.2 μM, 11.2 μM respectively). Uvagrandol can be used in the research of Type 2 diabetes and obesity .

HY-N11999

5,4'-Dihydroxy-3,4,3'-trimethoxybibenzyl	Structural Classification Orchidaceae Source classification Phenols Polyphenols Dendrobium wattii (J. D. Hooker) H. G. Reichenbach Plants	Others
5,4'-Dihydroxy-3,4,3'-trimethoxybibenzyl (compound 8) can be isolated from Dendrobium infundibulum (D. infundibulum). 5,4'-Dihydroxy-3,4,3'-trimethoxybibenzyl has no inhibitory activity against α-glucosidase and pancreatic lipase .

HY-N3797A

Echitamine chloride Ditaine chloride	Apocynaceae Alkaloids Structural Classification Classification of Application Fields Source classification Alstonia scholaris (L.) R. Br. Plants Disease Research Fields Indole Alkaloids Cancer	Apoptosis
Echitamine (Ditaine) chloride is the major monoterpene indole alkaloid present in Alstonia scholaris with potent anti-tumour activity. Echitamine chloride induces DNA fragmentation and cells apoptosis. Echitamine chloride inhibits pancreatic lipase with an IC₅₀ of 10.92 μM .

HY-N8989

(1,5E,11E)-Tridecatriene-7,9-diyne-3,4-diacetate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Plants Compositae Disease Research Fields Erythrina sigmoidea Hua	Others
(1,5E,11E)-Tridecatriene-7,9-diyne-3,4-diacetate, isolated from the ethanol extract of Atractylodes lancea rhizome, displays significant lipase inhibition with an IC₅₀ value of 23.9 µg/mL. Antiobesity Effect .

HY-N13198

4-(4-Hydroxyphenyl)-2-butanone 4'-O-β-D-(2-O-galloyl-6-O-cinnamoyl)glucopyranoside	Structural Classification Rhodiola sacra (Prain ex Raym.-Hamet) S. H. Fu Crassulaceae Source classification Phenols Polyphenols Plants	Endogenous Metabolite
4-(4-Hydroxyphenyl)-2-butanone 4'-O-β-D-(2-O-galloyl-6-O-cinnamoyl)glucopyranoside is a pancreatic lipase inhibitor, with an IC₅₀ value of 2.91 μM. 4-(4-Hydroxyphenyl)-2-butanone 4'-O-β-D-(2-O-galloyl-6-O-cinnamoyl)glucopyranoside can effectively reduce lipid absorption and regulate obesity-related metabolic disorders, making it useful for research on obesity .

HY-N7668

Neotheaflavin	Flavonoids Classification of Application Fields Flavanols Source classification Phenols Polyphenols Metabolic Disease Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Theaceae	Others
Neotheaflavin, from black tea, inhibits pancreatic lipase .

HY-N1937

Pristimerin 3 Publications Verification Celastrol methyl ester	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Celastraceae Tripterygium wilfordii Hook. f. Plants Disease Research Fields Cancer	Bacterial
Pristimerin is a potent and reversible monoacylglycerol lipase (MGL) inhibitor with an IC₅₀ of 93 nM.

HY-N7072

Grape seed extract 1 Publications Verification	Natural Products Classification of Application Fields Source classification Vitis vinifera cv. Zalema Metabolic Disease Plants Vitaceae Disease Research Fields Inflammation/Immunology	Apoptosis
Grape seed extract is a natural product, with anti-inflammatory and anti-proliferative effects. Grape seed extract shows inhibitory activity on the fat-metabolizing enzymes pancreatic lipase and lipoprotein lipase. Grape seed extract induces apoptotic in human colorectal cancer cells .

HY-N2816

Actinidic acid	Triterpenes Structural Classification Ketones, Aldehydes, Acids Terpenoids Source classification Plants Actinidiaceae Actinidia arguta (Sieb. & Zucc) Planch. ex Miq.	Others
Actinidic acid, a coumaroyl triterpene, is a pancreatic lipase inhibitor, with an IC₅₀ of 14.95 μM .

HY-119741

Salacinol	Structural Classification Natural Products Source classification Salacia reticulata Wight Celastraceae Plants	Lipase
Salacinol can be isolated from the roots of the plant Salacia reticulata. Salacinol inhibits fat metabolizing enzymes, such as pancreatic lipase (PL, IC₅₀=12.6 mg/L), lipoprotein lipase (LPL, IC₅₀=13.6 mg/L), and glycerophosphate dehydrogenase (GPDH), enhances the lipolysis, and exhibits antiobesity efficacy in rats .

HY-W004282

Undecanoic acid Undecanoate; Hendecanoic acid	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Fungal Endogenous Metabolite
Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum .

HY-N2087

Ligupurpuroside A	Structural Classification Oleaceae Simple Phenylpropanols Source classification Phenylpropanoids Ligustrum expansum Rehder Plants	Others
Ligupurpuroside A is an active product that can be extracted from Ligustrum robustum. Ligupurpuroside A acts as a natural inhibitor of lipase in a competitive manner .

HY-N1937R

Pristimerin (Standard)	Triterpenes Structural Classification Terpenoids Source classification Celastraceae Tripterygium wilfordii Hook. f. Plants	Bacterial
Pristimerin (Standard) is the analytical standard of Pristimerin. This product is intended for research and analytical applications. Pristimerin is a potent and reversible monoacylglycerol lipase (MGL) inhibitor with an IC₅₀ of 93 nM.

HY-N12893

Sclerodione	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal Lipase
Sclerodione is a metabolite that can be produced by the Scleroderris canker fungus, Gremmeniellaabietina. Sclerodione has antifungal activity. Sclerodione is a *lipase* inhibitor (IC₅₀: 1 μM) .

HY-N0555

Escin IB	Triterpenes Classification of Application Fields Terpenoids Hippocastanaceae Source classification Aesculus hippocastanum Metabolic Disease Plants Disease Research Fields	Others
Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum). Escin IB shows inhibitory effect on pancreatic lipase activity .

HY-N4167

3-O-Methylgalangin Galangin 3-methyl ether; 3-Methylgalangin	Infection Flavonols Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Alpinia officinarum Hance Plants Disease Research Fields Zingiberaceae	Bacterial
3-O-Methylgalangin (Galangin 3-methyl ether) is a natural flavonoid compound from the rhizome of Alpinia officinarum (AO) with antibacterial activities, which also inhibits pancreatic lipase .

HY-N0618

Sanggenon D	Flavanonols Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Plants Moraceae Inflammation/Immunology Disease Research Fields Morus alba Linn.	Others
Sanggenon D is a Diels-Alder-type adduct from Chinese crude agent root bark of mulberry ( Morus alba L.). Sanggenon D possesses antioxidant and inhibits Pancreatic lipase (PL) with the an IC50 of 0.77 μM.

HY-W004282R

Undecanoic acid (Standard) Undecanoate (Standard); Hendecanoic acid (Standard)	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Fungal Endogenous Metabolite
Undecanoic acid (Standard) is the analytical standard of Undecanoic acid. This product is intended for research and analytical applications. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum .

HY-N0555R

Escin IB (Standard)	Triterpenes Structural Classification Terpenoids Hippocastanaceae Aesculus hippocastanum Source classification Plants	Others
Escin IB (Standard) is the analytical standard of Escin IB. This product is intended for research and analytical applications. Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum). Escin IB shows inhibitory effect on pancreatic lipase activity .

HY-126564

Ebelactone A	Structural Classification Natural Products Microorganisms Source classification	Lipase MetAP
Ebelactone A is a mycolic acid β-lactone, which exhibits inhibitory activity for esterase, *lipase, fMet aminopeptidase (fMet AP) and PNBase, with IC₅₀s of 56, 3, 8 and 7.5 μM, respectively . Ebelactone A inhibits cutinase, exhibits plants protective potency against Erysiphe graminis* .

HY-N0313

Euphol	Triterpenes Structural Classification Classification of Application Fields Terpenoids Euphorbiaceae Plants Inflammation/Immunology Disease Research Fields	MAGL Endogenous Metabolite
Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the *monoacylglycerol lipase* (MGL) activity via a reversible mechanism (IC₅₀**=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain .

HY-N2330

Lipstatin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Others
Lipstatin is a pancreatic lipase inhibitor (IC₅₀=0.14 μM), whose structure is closely related to the known inhibitor, Esterastin. Lipstatin inhibits the absorption of triglycerides without affecting the absorption of oleic acid. Lipstatin has no inhibitory effects on other pancreatic enzymes, such as phospholipase A2 and trypsin (<200 μM) .

HY-N4298

Epitheaflagallin 3-O-gallate	Classification of Application Fields Source classification Phenols Polyphenols Plants Camellia sinensis (L.) O. Ktze. Disease Research Fields Inflammation/Immunology Theaceae	MMP
Epitheaflagallin 3-O-gallate is a minor polyphenol in black tea. Epitheaflagallin 3-O-gallate exhibits versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinusglycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts .

HY-W145699

D-myo-Inositol 4-monophosphate	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Biochemical Assay Reagents Endogenous Metabolite
D-myo-Inositol 4-mono-phosphate, also known as IMP, is a phosphorylated form of inositol that is commonly found in various metabolic pathways, especially in the biosynthesis of phospholipids and cell signaling molecules. D-myo-Inositol 4-mono-phosphate has unique chemical properties that make it an important intermediate in the production of second messengers, such as inositol triphosphate (IP3) and diacylglycerol (DAG), which signal in cells plays a key role in. D-myo-Inositol 4-mono-phosphate is also used in dietary supplements and pharmaceuticals because of its potential health benefits, including improved insulin sensitivity and cognitive function.

Species:	Human (13) Rat (2) Mouse (2) Dog (1)
Tag:	His (17) SUMO (2) Tag Free (1) Myc (1)
Source:	HEK293 (7) P. pastoris (3) Sf9 insect cells (4) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P70262

	*Gastric lipase* Protein, Human (HEK293, His, solution)** 1 Publications Verification rHuGastric triacylglycerol lipase/LIPF, His ; Gastric Triacylglycerol lipase; GL; Gastric lipase; LIPF	Human	HEK293
	Gastric lipase is a key enzyme in the digestive process and plays a key role in the hydrolysis of triacylglycerols into free fatty acids, diacylglycerols, monoacylglycerols, and glycerol. This enzyme activity contributes significantly to the breakdown of dietary fat in the gastric environment. Gastric lipase Protein, Human (HEK293, His) is the recombinant human-derived Gastric lipase protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70262A

	*Gastric lipase* Protein, Human (HEK293, C-His)** rHuGastric triacylglycerol lipase/LIPF, His ; Gastric Triacylglycerol lipase; GL; Gastric lipase; LIPF	Human	HEK293
	Gastric lipase is a key enzyme in the digestive process and plays a key role in the hydrolysis of triacylglycerols into free fatty acids, diacylglycerols, monoacylglycerols, and glycerol. This enzyme activity contributes significantly to the breakdown of dietary fat in the gastric environment. Gastric lipase Protein, Human (HEK293, C-His) is the recombinant human-derived Gastric lipase protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Gastric lipase Protein, Human (HEK293, C-His) is 379 a.a., with molecular weight of ~48.09 kDa.

HY-P75978

	*PNLIP/Pancreatic lipase* Protein, Human (HEK293, His)** PnlipPancreatic triacylglycerol lipase; PL; PTL; Pancreatic lipase	Human	HEK293
	PNLIP/Pancreatic lipase Protein is pivotal in fat metabolism, preferentially cleaving esters of long-chain fatty acids at positions 1 and 3, yielding 2-monoacylglycerol and free fatty acids. It displays increased activity with insoluble emulsified substrates over soluble ones. PNLIP/Pancreatic lipase Protein, Human (HEK293, His) is the recombinant human-derived PNLIP/Pancreatic lipase protein, expressed by HEK293 , with C-His, C-8*His labeled tag. The total length of PNLIP/Pancreatic lipase Protein, Human (HEK293, His) is 449 a.a., with molecular weight of ~51 kDa.

HY-P75311

	DAG1 Protein, Human (HEK293, His) Dystroglycan 1; Alpha-DG; Beta-DG; DAG1	Human	HEK293
	DAG1 Proteinas, a pivotal extracellular glycoprotein, is crucial for laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Serving as a receptor for laminin-G domain-containing extracellular matrix proteins, DAG1 interacts with laminin-2 (LAMA2) and agrin in peripheral nerve Schwann cells and acts as a receptor for laminin LAMA5. DAG1 Protein, Human (HEK293, His) is the recombinant human-derived DAG1 protein, expressed by HEK293 , with C-His labeled tag. The total length of DAG1 Protein, Human (HEK293, His) is 720 a.a., with molecular weight (glycosylation form) of ~95-110 kDa, 55-95 kDa, 17-20 kDa.

HY-P701985

	MGLL Protein, Human (His) MGLL; Monoglyceride lipase; MGL; HU-K5; Lysophospholipase homolog; Lysophospholipase-like; Monoacylglycerol lipase; MAGL	Human	E. coli
	MGLL proteins convert monoacylglycerides into free fatty acids and glycerol. MGLL Protein, Human (His) is the recombinant human-derived MGLL protein, expressed by E. coli , with N-6*His labeled tag. The total length of MGLL Protein, Human (His) is 302 a.a., .

HY-P71755

	*Monoglyceride lipase* Protein, Rat (P.pastoris, His)** Mgll; Mgl2; Monoglyceride lipase; MGL; Monoacylglycerol lipase; MAGL	Rat	P. pastoris
	Monoglyceride lipase is a key enzyme in lipid metabolism and plays a key role in converting monoacylglycerols into free fatty acids and glycerol, contributing to important cellular processes. In addition to being involved in lipid metabolism, this enzyme also hydrolyzes the endocannabinoid 2-arachidonoylglycerol, thereby affecting the complex regulation of endocannabinoid signaling, nociception, and pain perception. Monoglyceride lipase Protein, Rat (P.pastoris, His) is the recombinant rat-derived Monoglyceride lipase protein, expressed by P. pastoris , with N-His labeled tag. The total length of Monoglyceride lipase Protein, Rat (P.pastoris, His) is 303 a.a., with molecular weight of ~35.5 kDa.

HY-P71582

	*PNLIP/Pancreatic lipase* Protein, Mouse (His-SUMO)** PnlipPancreatic triacylglycerol lipase; PL; PTL; Pancreatic lipase; EC 3.1.1.3	Mouse	E. coli
	Pancreatic lipase (PNLIP) plays a crucial role in fat metabolism by enzymatically breaking down dietary lipids and preferentially selecting long-chain fatty acid esters at positions 1 and 3. This results in the production of mainly 2-monoacylglycerol and free fatty acids. PNLIP/Pancreatic lipase Protein, Mouse (His-SUMO) is the recombinant mouse-derived PNLIP/Pancreatic lipase protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

HY-P703648

	LIPA Protein, Human (P. pastoris, His) Lysosomal acid lipase/cholesteryl ester hydrolase; Cholesteryl esterase; Diacylglycerol lipase; Sterol esterase	Human	P. pastoris

HY-P74352

	*Carboxyl Ester Lipase/CEL Protein, Mouse (sf9, His)* Bile salt-activated lipase; BAL; BSSL; Cel; Lip1	Mouse	Sf9 insect cells
	Carboxyester lipase/CEL protein plays a crucial role in cellular processes as it catalyzes the hydrolysis of a variety of substrates, including cholesterol esters, phospholipids, lysophospholipids, diacylglycerols and triacylglycerols, and lipids of hydroxy fatty acids acid ester. FAHF). Carboxyl Ester Lipase/CEL Protein, Mouse (sf9, His) is the recombinant mouse-derived Carboxyl Ester Lipase/CEL protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Carboxyl Ester Lipase/CEL Protein, Mouse (sf9, His) is 534 a.a., with molecular weight of ~133.9 & 59.1 kDa, respectively.

HY-P701984

	MGLL Protein, Human MGLL; Monoglyceride lipase; MGL; HU-K5; Lysophospholipase homolog; Lysophospholipase-like; Monoacylglycerol lipase; MAGL	Human	E. coli
	MGLL proteins convert monoacylglycerides into free fatty acids and glycerol. MGLL Protein, Human is the recombinant human-derived MGLL protein, expressed by E. coli , with tag free. The total length of MGLL Protein, Human is 302 a.a., .

HY-P77149

	PLRP2 Protein, Human (sf9, His) Pancreatic lipase-related protein 2; PL-RP2; Galactolipase; PNLIPRP2	Human	Sf9 insect cells
	The PLRP2 protein is a multifunctional lipase that hydrolyzes triglycerides and galactosylglycerides with broad substrate specificity. It is essential for newborns and plays an important role in the pancreas' digestion of dietary fats, especially milk fat globules, which are rich in long-chain triglycerides. PLRP2 Protein, Human (sf9, His) is the recombinant human-derived PLRP2 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of PLRP2 Protein, Human (sf9, His) is 469 a.a., with molecular weight of ~57 kDa.

HY-P70991

	PLRP1 Protein, Human (HEK293, His) Pancreatic lipase-Related Protein 1; PL-RP1; PNLIPRP1; PLRP1	Human	HEK293
	PLRP1 Protein is a protein that encoded by PNLIPRP1 genne. PLRP1 is produced by pancreatic acinar cells and expressed in the pancreas. PLRP1 is involved in lipid catabolic process, acting as a negative regulator of pancreatic lipase activity by competing with pancreatic lipase for colipase occupancy. And it may function as inhibitor of dietary triglyceride digestion. PLRP1 Protein, Human (HEK293, His) is the recombinant human-derived PLRP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PLRP1 Protein, Human (HEK293, His) is 450 a.a., with molecular weight of 44-50 kDa.

HY-P70972

	PNLIPRP2 Protein, Human (HEK293, His) Pancreatic lipase-Related Protein 2; PL-RP2; Galactolipase; PNLIPRP2; PLRP2	Human	HEK293
	PNLIPRP2 Protein, Human (HEK293, His) is the recombinant human-derived PNLIPRP2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PNLIPRP2 Protein, Human (HEK293, His) is 452 a.a., with molecular weight of ~62.0 kDa.

HY-P71770

	PNLIPRP1 Protein, Dog (P.pastoris, His) PNLIPRP1; PLRP1; Inactive pancreatic lipase-related protein 1; PL-RP1	Dog	P. pastoris
	The PNLIPRP1 protein acts as an inhibitor of dietary triglyceride digestion and lacks lipase activity on various substrates. This regulatory effect suggests an effect on the breakdown of dietary triglycerides. PNLIPRP1 Protein, Dog (P.pastoris, His) is the recombinant dog-derived PNLIPRP1 protein, expressed by P. pastoris , with N-His labeled tag.

HY-P77464

	PNLIPRP1 Protein, Rat (HEK293, His) PNLIPRP1; PLRP1; Inactive pancreatic lipase-related protein 1; PL-RP1	Rat	HEK293
	PNLIPRP1 Protein, a potential inhibitor of dietary triglyceride digestion, likely modulates lipid metabolism. In vitro analyses reveal its lack of detectable lipase activity, suggesting a unique role as an enzyme inhibitor rather than an active participant in triglyceride hydrolysis. This characteristic underscores PNLIPRP1's potential regulatory impact on lipid digestion processes. PNLIPRP1 Protein, Rat (HEK293, His) is the recombinant rat-derived PNLIPRP1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76133

	ABHD4 Protein, Human (sf9, His) (Lyso)-N-acylphosphatidylethanolamine lipase; Alpha/beta-hydrolase 4; ABHD4	Human	Sf9 insect cells
	ABHD4 is a lysophospholipase that acts selectively on N-acylphosphatidylethanolamines (NAPE), which is essential for the biosynthesis of N-acylphosphatidylethanolamines such as anandamide. It hydrolyzes the sn-1 and sn-2 acyl chains in NAPE to generate glycerophosphate-N-acylethanolamine (GP-NAE), which is an important intermediate in the production of N-acylethanolamine. ABHD4 Protein, Human (sf9, His) is the recombinant human-derived ABHD4 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of ABHD4 Protein, Human (sf9, His) is 342 a.a., with molecular weight of ~40 KDa.

HY-P702617

	DGKA Protein, Human (sf9, His, Myc) 80 kDa diacylGlycerol kinase; DAG kinase alpha; DAGK; DAGK1; DGK alpha; DGK-alpha; dgkA; DGKA_HUMAN; DiacylGlycerol kinase alpha; DiacylGlycerol kinase; alpha 80kDa; Diglyceride kinase alpha; MGC12821; MGC42356; OTTHUMP00000242836; OTTHUMP00000242955; OTTHUMP00000244046	Human	Sf9 insect cells
	The DGKA protein converts diacylglycerol (DAG) into phosphatidic acid (PA), regulates its levels and serves as a central switch between signaling pathways. DGKA Protein, Human (sf9, His, Myc) is the recombinant human-derived DGKA, expressed by Sf9 insect cells , with C-Myc, N-10*His labeled tag. The total length of DGKA Protein, Human (sf9, His, Myc) is 735 a.a.,

HY-P71600

	PNPLA2 Protein, Human (His-SUMO) 1110001C14Rik ; Adipose triglyceride lipase; ATGL; ATGL DESNUTRIN; Desnutrin; EC 3.1.1.3; FP17548; IPLA2 zeta; IPLA2-zeta; PEDF R; Pigment epithelium derived factor; Pigment epithelium-derived factor; plpl; plpl2; PLPL2_HUMAN; Pnpla2; Transport secretion protein 2; Transport secretion protein 2.2; Transport-secretion protein 2; Triglyceride hydrolase ; TTS 2.2; TTS2; TTS2.2; ZETA	Human	E. coli
	The PNPLA2 protein catalyzes the hydrolysis of triglycerides, preferably long-chain fatty acid esters, in lipid droplets. PNPLA2 Protein, Human (His-SUMO) is the recombinant human-derived PNPLA2 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-W004282S

Undecanoic acid-d21
Undecanoic acid-d₂₁ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-W004282S1

Undecanoic acid-d3
Undecanoic acid-d₃ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-W004282S2

Undecanoic acid-d2
Undecanoic acid-d₂ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-B0218S

Orlistat-d3
Orlistat-d3 is a deuterated labeled Orlistat . Orlistat (Tetrahydrolipstatin) is a well-known irreversible inhibitor of pancreatic and gastric *lipases. Orlistat is also an inhibitor of fatty acid synthase (FASN*), is used orally for long-term research of obesity .?Anti-atherosclerotic?effect .

HY-131897S

1-Stearoyl-2-Arachidonoyl-d8-sn-Glycerol
1-Stearoyl-2-Arachidonoyl-d₈-sn-Glycerol is the deuterium labeled 1-Stearoyl-2-arachidonoyl-sn-glycerol. 1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity[1][2].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80464

	*Phospho-Hormone sensitive lipase* (Ser853) Antibody** Hormone sensitive lipase antibody; Hormone sensitive lipase testicular isoform antibody; Hormone-sensitive lipase antibody; HSL antibody; LHS; lipase hormone sensitive antibody; LIPE antibody; LIPS_HUMAN antibody; Phospho-Hormonesensitivelipase(S853); PhosphoHormonesensitivelipase(S853)	WB, IHC-P	Human, Mouse, Rat
	Phospho-Hormone sensitive lipase (Ser853) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 117 kDa, targeting to Phospho-Hormone sensitive lipase (S853). It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P80533

	*Adipose Triglyceride Lipase* Antibody** ATGL; Desnutrin; plpl; plpl2; Pnpla2; TTS 2.2; TTS2; TTS2.2; ZETA	WB	Human, Mouse, Rat
	Adipose Triglyceride Lipase Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 55 kDa, targeting to Adipose Triglyceride Lipase. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P81831

	*Lipoprotein Lipase* Antibody (YA1576)** LPL; LIPD; Lipoprotein lipase; LPL	WB, IHC-P	Human
	Lipoprotein Lipase Antibody (YA1576) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1576), targeting Lipoprotein Lipase, with a predicted molecular weight of 53 kDa (observed band size: 53 kDa). Lipoprotein Lipase Antibody (YA1576) can be used for WB, IHC-P experiment in human background.

HY-P81503

	*Pancreatic Lipase* Antibody (YA1248)** Pancreatic lipase; PL; PNLIP; PNLIPD; PTL	IHC-P	Human
	Pancreatic Lipase Antibody (YA1248) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1248), targeting Pancreatic Lipase. Pancreatic Lipase Antibody (YA1248) can be used for IHC-P experiment in human background.

HY-P83006

	beta Dystroglycan Antibody (YA2751) A3a; DAG; AGRNR; 156DAG; MDDGA9; MDDGC7; MDDGC9; LGMDR16	WB	Human
	beta Dystroglycan Antibody (YA2751) is a biotin-conjugated non-conjugated IgG antibody, targeting beta Dystroglycan, with a predicted molecular weight of 97 kDa (observed band size: 42-44 kDa). beta Dystroglycan Antibody (YA2751) can be used for WB experiment in human background.

HY-P82854

	*Phospho-Hormone Sensitive Lipase* (Ser855) Antibody (YA2599)** LIPE; Hormone-sensitive lipase; HSL	WB	Human
	Phospho-Hormone Sensitive Lipase (Ser855) Antibody (YA2599) is a biotin-conjugated non-conjugated IgG antibody, targeting Phospho-Hormone Sensitive Lipase (Ser855), with a predicted molecular weight of 117 kDa (observed band size: 83 kDa). Phospho-Hormone Sensitive Lipase (Ser855) Antibody (YA2599) can be used for WB experiment in human background.

HY-P83201

	*Monoacylglycerol Lipase* Antibody (YA2946)** HUK5; Lysophospholipase homolog; Lysophospholipase like; MAGL; MGL; MGLL; Monoacylglycerol lipase	WB	Human
	Monoacylglycerol Lipase Antibody (YA2946) is a biotin-conjugated non-conjugated IgG antibody, targeting Monoacylglycerol Lipase, with a predicted molecular weight of 33 kDa (observed band size: 33 kDa). Monoacylglycerol Lipase Antibody (YA2946) can be used for WB experiment in human background.

HY-P82323

	alpha Sarcoglycan Antibody (YA2068) SGCA; ADL; DAG2; Alpha-sarcoglycan; Alpha-SG; 50 kDa dystrophin-associated glycoprotein; 50DAG; Adhalin; Dystroglycan-2	WB, IHC-P, IP	Human, Mouse, Rat
	alpha Sarcoglycan Antibody (YA2068) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2068), targeting alpha Sarcoglycan, with a predicted molecular weight of 43 kDa (observed band size: 50 kDa). alpha Sarcoglycan Antibody (YA2068) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

HY-P83716

	Alpha-dystroglycan Antibody 156DAG antibody; A3a antibody; AGRNR antibody; Alpha dystroglycan antibody; Alpha-DG antibody; Beta-DG antibody; Beta-dystroglycan antibody; DAG antibody; DAG1 antibody; DAG1_HUMAN antibody; Dystroglycan 1 (dystrophin associated glycoprotein 1) antibody; Dystroglycan antibody; Dystrophin associated glycoprotein 1 antibody; Dystrophin-associated glycoprotein 1 antibody; OTTHUMP00000210857 antibody; OTTHUMP00000210858 antibody	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	Alpha-dystroglycan Antibody is an unconjugated, approximately 97 kDa, rabbit-derived, anti-Alpha-dystroglycan polyclonal antibody. Alpha-dystroglycan Antibody can be used for: WB, IHC-P, IF-Cell, FC expriments in human,mouse and rat background without labeling.

HY-P83581

	delta Sarcoglycan Antibody (YA3326) 35DAG; CMD1L; DAGD; Delta-sarcoglycan; LGMD2F; SG delta; SGCD; SGCDP	WB, IHC-P, IP	Human
	delta Sarcoglycan Antibody (YA3326) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3326), targeting delta Sarcoglycan, with a predicted molecular weight of 32 kDa (observed band size: 35 kDa). delta Sarcoglycan Antibody (YA3326) can be used for WB, IHC-P, IP experiment in human background.

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Cat. No.	Product Name		Classification

HY-120171

DH-376		Alkynes
DH-376 is a potent diacylglycerol lipase inhibitor with pIC₅₀ values of 8.6 and 8.9 for ABHD6 and DAGLα, respectively. DH-376 prevents fasting-induced refeeding of mice . DH-376 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-D1005

Poloxamer 407 (F127) 2 Publications Verification PEG-PPG-PEG, 12600 (Average Mn)		Emulsifiers Solubilizing Agents
Poloxamer 407 (F127) is a nonionic surfactant that is 100% active and relatively non-toxic to cells at low concentrations, and frequently used with dye AM esters such as Indo-1 AM, Fura-2 AM, Calcein AM, Fluo-3 AM, Fluo-4 AM, Quest Fluo-8? AM and Quest Rhod-4? AM, etc. to improve their water solubility. Poloxamer 407 is also a lipoprotein lipase inhibitor .

HY-RS03519

DAG1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
DAG1 Human Pre-designed siRNA Set A contains three designed siRNAs for DAG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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DAG lipase

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