Search Result
Results for "
label peptide
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
65
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-131326
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- HY-W039519
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Fluorescent Dye
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Cancer
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7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye with an excitation peak at 355 nm and an emission peak at 405 nm. 7-Methoxycoumarin-3-carboxylic acid can be used to label peptide .
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- HY-W539893
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NODAG
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Biochemical Assay Reagents
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Cancer
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NODAGA-tris(t-Bu ester) (NODAG) is a NODAGA derivative. NODAGA-tris(t-Bu ester) can be used to label peptides, antibodies, etc., and subsequently radiolabeled for PET imaging .
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- HY-15938
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Fluorescent Dye
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Others
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5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates .
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- HY-P4138
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Fluorescent Dye
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Cancer
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Antennapedia Peptide FAM-labeled is a fluorophore labeled peptide. Antennapedia Peptide FAM-labeled also can be used for the research of cancer as a molecular probe .
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- HY-151496
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Others
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Others
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H-Cys-Val-2-Nal-Met-OH is a peptide. H-Cys-Val-2-Nal-Met-OH is a peptidomimetic derivative that can be used to label short peptide sequences .
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- HY-D1405
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- HY-W755222
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(S)-NODAG
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Biochemical Assay Reagents
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Cancer
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(S)-NODAGA-tris(t-Bu ester) ((S)-NODAG) is a NODAGA derivative. (S)-NODAGA-tris(t-Bu ester) can be used to label peptides, antibodies, etc., and subsequently radiolabeled for PET imaging .
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- HY-W591317
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(R)-NODAG
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Radionuclide-Drug Conjugates (RDCs)
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Cancer
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(R)-NODAGA-tris(t-Bu ester) ((R)-NODAG) is a NODAGA derivative. (R)-NODAGA-tris(t-Bu ester) can be used to label peptides, antibodies, etc., and subsequently radiolabeled for PET imaging .
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- HY-114350
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Fluorescent Dye
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Others
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BDP FL maleimide is a thiol-reactive dye (Ex: 503 nm; Em: 509 nm). BDP FL maleimide can be used for protein labeling, peptide modification, and can replace fluorescein (FAM) for microscopy .
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- HY-P5915
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HIF/HIF Prolyl-Hydroxylase
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Cancer
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FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2, a 5-FAM labeled HIF-1α peptide, is a substrate of VHL. FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2 binds to VHL protein with a KD of 3 nM. Ex/Em (λ) = 485/520 nm .
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- HY-15940
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5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers
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Fluorescent Dye
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Cancer
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5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .
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- HY-147104
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Fluorescent Dye
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Others
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Fmoc-Lys(5-FITC)-OH is a marker for polypeptides or proteins. FITC is a fluorescence probe for the labeling of amines. FITC is a pH- and Cu 2+-sensitive fluorescence dye .
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- HY-P0014AS
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- HY-P10292
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- HY-156341S1
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- HY-156345S1
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- HY-156344S1
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- HY-156343S1
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- HY-P0014S1
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Isotope-Labeled Compounds
GLP Receptor
GCGR
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Others
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Liraglutide- 13C5, 15N (tetraTFA) is the 13C and 15N labeled Liraglutide (HY-P0014) . Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
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- HY-P5969
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- HY-P6424S
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- HY-P6421S
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- HY-P6423S
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- HY-P6425S
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- HY-P6422S
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- HY-P2504
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Syk
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Others
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Syk Kinase Peptide Substrate, Biotin labeled is a biotin-labled Syk kinase peptide substrate.
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- HY-P5433F
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Insulin Receptor
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Others
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IRS-1 Peptide, FAM labeled is a biological active peptide. (Insulin receptor substrate)
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- HY-P3616
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GCGR
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Metabolic Disease
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Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide is a biotin labeled glucagon-like peptide-1-(7-36). Glucagon-like peptide-1-(7-36) is a gastrointestinal peptide with antidiabetogenic activity, and can increase the release of insulin .
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- HY-P1459
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Bacterial
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Infection
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Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) is a truncated fragments of Sphistin Synthetic Peptide that shows potent antimicrobial activity.
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- HY-P4083
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Fluorescent Dye
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Others
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(Arg)9,TAMRA-labeled is a TAMRA-labeled cell permeable peptide. (Arg)9 is a cell-permeable peptide used for drug delivery .
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- HY-P5325F
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Bcl-2 Family
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Others
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Bid BH3 (80-99), FAM labeled is a biological active peptide. (This is a 5-FAM-labeled Bid BH3 HY-P5325 peptide.)
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- HY-D0017
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DNSCl
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Fluorescent Dye
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Others
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Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis .
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- HY-P4135
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Fluorescent Dye
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Others
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FITC-LC-Antennapedia Peptide is a FITC labeled Antennapedia Peptide (HY-P0307). Antennapedia Peptide is a cellular-membrane permeable peptides (CPP). FITC-LC-Antennapedia Peptide has good penetration in 3T3 cell line, which was rapidly accumulated into nuclei .
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- HY-P0248F
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PKA
Fluorescent Dye
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Others
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Kemptide, 5-FAM labeled is a biological active peptide. (Kemptide is a phosphate acceptor peptide that serves as a synthetic substrate for PKA (Km = 16 μM). The corresponding fluorescent and biotinylated peptides are also proven to be good substrates for PKA. 5-FAM labeled HY-P0248)
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- HY-158992S
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Isotope-Labeled Compounds
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Others
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SP-(Val- 13C5, 15)-EKNQ-(Leu- 13C6, 15)-TIDFINIVKDPVPHNEYKT TFA is a 13C- and 15N-labeled peptide containing 13C5, 15N-labeled valine (Val) and 13C6, 15N-labeled leucine (Leu).
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- HY-P4105
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- HY-158994S
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Isotope-Labeled Compounds
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Others
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MEGDSRGG-(Ala- 13C3, 15N)-GGEA-(Leu- 13C6, 15N)-DPESAASSLSGAS TFA is a 13C- and 15N-labeled peptide containing 13C3, 15N-labeled alanine (Ala) and 13C6, 15N-labeled leucine (Leu).
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- HY-P0030
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- HY-P2292
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Bacterial
Fungal
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Infection
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Omiganan, FITC labeled is a peptide-FITC complex composed of Omiganan and a FITC. Omiganan is a bactericidal and fungicidal cationic peptide being developed as a topical gel for prevention of catheter-associated infections. FITC is a derivative of fluorescein for the labeling of amines .
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- HY-13443F
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GCGR
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Others
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Exendin 4, biotin labeled is a biological active peptide. (Biotin labeled HY-13443)
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- HY-P0201F
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- HY-P10183
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- HY-114118F
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GCGR
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Metabolic Disease
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Semaglutide, FITC labeled is a FITC labeled Semaglutide. Semaglutide, a long-acting GLP-1 alogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide has the potential for type 2 diabetes treatment .
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- HY-P0082F
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Fluorescent Dye
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Others
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Glucagon (1-29), FAM-labeled is a biological active peptide. (FAM labeled HY-P0082)
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- HY-P1755F
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- HY-P2491
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Fluorescent Dye
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Cardiovascular Disease
Endocrinology
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Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .
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- HY-P4125
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HIV
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Others
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FITC-LC-TAT (47-57) is a FITC labeled TAT peptide. TAT is a cell-penetrating peptide (CPP). TAT can increase the yields and the solubility of heterologous proteins .
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- HY-P2609F
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PACAP Receptor
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Others
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PACAP (1-38), amide, Biotin-labeled is a biological active peptide. (Biotin-labeled HY-P0221)
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- HY-P3146S
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Isotope-Labeled Compounds
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Cancer
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FTISADTSK- 13C6, 15N2 TFA is 13C- and 15N-labeled FTISADTSK (HY-P3146). FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM) .
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- HY-P4337
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- HY-D1081
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Fluorescent Dye
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Others
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6-DTAF hydrochloride is a fluorescein that can be used to label peptides and nucleotides .
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- HY-P0300F
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- HY-P2292A
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Bacterial
Fungal
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Infection
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Omiganan, FITC labeled TFA is a peptide-FITC complex composed of Omiganan and a FITC. Omiganan is a bactericidal and fungicidal cationic peptide being developed as a topical gel for prevention of catheter-associated infections .
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- HY-P4103
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- HY-P0206F
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- HY-P4337A
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- HY-13948F1
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Angiotensin II, FAM-labeled ; Ang II, FAM-labeled ; DRVYIHPF, FAM-labeled
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Angiotensin Receptor
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Others
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Angiotensin II human, FAM-labeled (Angiotensin II, FAM-labeled ; Ang II, FAM-labeled ; DRVYIHPF, FAM-labeled) is a biological active peptide. (FAM labeled HY-13948)
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- HY-P5351A
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Transmembrane Glycoprotein
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Inflammation/Immunology
Cancer
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Hyaluronan-binding peptide, biotin labeled TFA is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.) .
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- HY-15944
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5(6)-Carboxytetramethylrhodamine
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Fluorescent Dye
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Others
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5(6)-TAMRA is a fluorescent dye molecule widely used as a label for peptides and proteins.
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- HY-W087027
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- HY-D2495
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Fluorescent Dye
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Others
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Cy7 SE (nosulfo) is a fluorescent dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides.
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- HY-P10184
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Transmembrane Glycoprotein
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Inflammation/Immunology
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CD36 Peptide P (93-110), Cys conjugated is a Cys labelled CD36 Peptide, and can block binding of CD36 to immobilized thrombospondin and partially inhibited collagen-induced platelet aggregation .
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- HY-P3432
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Biochemical Assay Reagents
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Others
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DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .
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- HY-156144
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DBB chloride
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Biochemical Assay Reagents
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Others
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p-Diazobenzoyl-biocytin chloride is a biotin derivative that can be used for the labeling of tyrosine and histidines in peptides and proteins .
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- HY-P0286F1
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- HY-P5168S
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Isotope-Labeled Compounds
SARS-CoV
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Infection
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GPSVFPLAPSSK- 13C6, 15N2 is the 13C- and 15N-labeled GPSVFPLAPSSK. GPSVFPLAPSSK is an IgG1 signature peptide of anti-SARS-CoV-2 antibodies. GPSVFPLAPSSK can be used for the quantification of the specific isolation of anti-SARS-CoV-2 antibodies .
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- HY-P5168AS
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Isotope-Labeled Compounds
SARS-CoV
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Infection
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GPSVFPLAPSSK- 13C6, 15N2 TFA is the 13C- and 15N-labeled GPSVFPLAPSSK. GPSVFPLAPSSK is an IgG1 signature peptide of anti-SARS-CoV-2 antibodies. GPSVFPLAPSSK can be used for the quantification of the specific isolation of anti-SARS-CoV-2 antibodies .
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- HY-135414
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Fluorescent Dye
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Others
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Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
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- HY-P2496
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Endothelin Receptor
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Cardiovascular Disease
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Endothelin 1 (swine, human), Alexa Fluor 488-labeled is a synthetic Endothelin 1 peptide labled with Alexa Fluor 488. Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB .
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- HY-D0819A
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Cy5 NHS Ester triethylamine salt; Sulfo-Cyanine5 Succinimidyl Ester triethylamine salt
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Fluorescent Dye
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Others
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Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm) .
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- HY-P4122
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HIV
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Others
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TAT (47-57), FAM-labeled is a cell-penetrating peptide (CPP). TAT (47-57), FAM-labeled has the potential for intracellular drug delivery research .
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- HY-P2550A
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Amyloid-β
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Neurological Disease
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β-Amyloid (1-40), FAM-labeled TFA is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λex= 492 nm and λem= 518 nm).
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- HY-D0819
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Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester
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Fluorescent Dye
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Others
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Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.
Excitation (nm):649, Emission (nm): 670.
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- HY-106244A
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Radionuclide-Drug Conjugates (RDCs)
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Cancer
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DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) . DOTATATE (acetate) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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- HY-106244
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Radionuclide-Drug Conjugates (RDCs)
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Cancer
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DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) . DOTATATE can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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- HY-135414B
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Fluorescent Dye
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Others
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Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
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- HY-P2549
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- HY-P0286F1A
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- HY-P4154
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ALM-488
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Fluorescent Dye
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Neurological Disease
Cancer
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Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .
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- HY-W012479S
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- HY-D2290
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Fluorescent Dye
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Others
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Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .
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- HY-P1097F
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- HY-D1618
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Fluorescent Dye
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Others
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Cyanine3 maleimide tetrafluoroborate is a specific labeling reagent for sulfhydryl groups with the λex of 550 nm and λem of 580 nm. Cyanine3 maleimide tetrafluoroborate can be used for protein and peptide labeling .
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- HY-P2550
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Amyloid-β
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Neurological Disease
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β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled?β-Amyloid (1-40) peptide (λex=?492?nm and λem=?518?nm) .
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- HY-147050
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- HY-D1849
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Fluorescent Dye
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Others
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Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.
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- HY-147050A
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- HY-P2500
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Fluorescent Dye
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Others
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(Arg)9, FAM-labeled, a cell-penetrating peptide (CPP), is a nona-arginine (ARG) with FAM label. CPPs have emerged as powerful tools for delivering bioactive cargoes into the cytosol of intact cells .
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- HY-17571F
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Biotin-α-Hypophamine; Biotin-Oxytocic hormone
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Oxytocin Receptor
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Others
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Biotin-Oxytocin (Biotin-α-Hypophamine; Biotin-Oxytocic hormone) is a biological active peptide. (This is Oxytocin (HY-17571) N-terminally labeled with Biotin.)
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- HY-W738256
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MDTPA
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Radionuclide-Drug Conjugates (RDCs)
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Cancer
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Maleimide-DTPA (MDTPA) is a monoreactive DTPA derivative (MDTPA) with maleimide group as peptide binding site, which can be combined with radionuclides to prepare radionuclide conjugates (RDC). Maleimide-DTPA can chelate indium-111 (111In) and label peptides and peptides with indium-111. For example, it has high stability when combined with OST7 incubated in human serum, which is better than cyclic cDTPA. Maleimide-DTPA is a good material for medical imaging or treatment.
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- HY-135414A
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Fluorescent Dye
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Others
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Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues .
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- HY-P10792
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EGFR
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Cancer
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HER2-targeted peptide H6F is a HER2 targeting peptide that binds to HER2 to target breast cancer cells, with the amino acid sequence YLFFVFER. The HER2-targeted peptide H6F can be conjugated with the bifunctional chelating agent hydrazinonicotinamide (HYNIC) for radiolabeling with 99mTc. Single-photon emission computed tomography (SPECT) imaging shows that the labeled HER2-targeted peptide H6F specifically accumulates in HER2-positive MDA-MBA-453 tumor-bearing mice models. The HER2-targeted peptide H6F can be used for tumor molecular imaging studies .
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- HY-D2498
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Fluorescent Dye
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Others
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Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .
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- HY-D2439
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Fluorescent Dye
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Cancer
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RGD-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, peptide (RGD) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. RGD is a peptide sequence (CRGDKGPDCiRGD) that binds to αvβ3 and αvβ5 integrin receptors on tumor neovasculogenesis to achieve specific tumor tissue targeting .
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- HY-P0136F
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AMPK
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Others
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FAM-SAMS is a 5-FAM (HY-66022) labeled SAMS (HY-P0136). SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK) .
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- HY-P2535
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GLP Receptor
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Metabolic Disease
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Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human is an C-terminal-labelled biotinylated GLP-1 (7-36) amide.
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- HY-13948F
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Biotin-Ahx-Angiotensin II; Biotin-Ahx-Ang II; Biotin-Ahx-DRVYIHPF
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Angiotensin Receptor
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Others
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Biotin-Ahx-Angiotensin II human (Biotin-Ahx-Angiotensin II; Biotin-Ahx-Ang II; Biotin-Ahx-DRVYIHPF) is a biological active peptide. (biotin labeled HY-13948)
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- HY-P1362FA
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Cy5-Amyloid β peptide (42-1)(human) Tris
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Amyloid-β
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Neurological Disease
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Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λex= 633 nm and λem= 670 nm) .
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- HY-P0136AF
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Fluorescent Dye
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Others
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FAM-SAMS TFA is a 5-FAM (HY-66022) labeled SAMS (HY-P0136). SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK) .
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- HY-P1363F1
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Biotin-amyloid β-peptide (1-42) (human) TFA
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Amyloid-β
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Neurological Disease
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Biotin-β-Amyloid (1-42), human TFA (Biotin-Amyloid β-Peptide (1-42) (human) TFA) is the botin labeled β-Amyloid (1-42), human TFA (HY-P1363). β-Amyloid (1-42), human TFA is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
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- HY-D2488
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Fluorescent Dye
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Others
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Sulfo Cy5.5-maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides.
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-
- HY-P1362F
-
|
Cy5-Amyloid β peptide (42-1)(human)
|
Amyloid-β
|
Neurological Disease
|
|
Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λex= 633 nm and λem= 670 nm) .
|
-
- HY-P1032F
-
|
|
Endogenous Metabolite
|
Endocrinology
|
|
Biotinyl-Angiotensin I (human, mouse, rat) is biotin-labeled Angiotensin I . Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE) .
|
-
- HY-D1756
-
|
|
Fluorescent Dye
|
Others
|
|
ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer.
|
-
- HY-P2499
-
|
|
Bcl-2 Family
|
Cancer
|
|
BAD (103-127) (human), FAM-labeled is a FAM-labeled human BAD (103-127) (HY-P2468). BAD (103-127) (human), the 25-mer Bad peptide, is derived from the BH3 domain of BAD, can antagonize the function of Bcl-xL .
|
-
- HY-W879234
-
|
Sulfo Cy5.5-DBCO
|
Fluorescent Dye
|
Others
|
|
TriSulfo-Cy5.5 DBCO is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.TriSulfo-Cy5.5 DBCO can be used to label proteins, antibodies, peptides, nucleic acid molecules.
|
-
- HY-66022
-
5-FAM
3 Publications Verification
5-Carboxyfluorescein
|
Fluorescent Dye
|
Others
|
|
5-FAM (5-Carboxyfluorescein) is a green fluorescent reagent used for in situ labeling peptides, proteins and nucleotides. 5-FAM is a single isomer with Ex/Em of 490 nm/520 nm .
|
-
- HY-P10202
-
|
|
STAT
|
Cancer
|
|
5-FAM-GpYLPQTV-NH2 is a fluorescently labeled peptide and has STAT3 inhibitory activity. 5-FAM-GpYLPQTV-NH2 can be used in cancer research .
|
-
- HY-P5367
-
|
PMDM6-F
|
Fluorescent Dye
|
Others
|
|
5-FAM-PMDM6 (PMDM6-F) is a biological active peptide. (PMDM6-F is a fluorescent-labeled probe for MDM2-binding assay.)
|
-
- HY-149117
-
|
|
Fluorescent Dye
|
Others
|
|
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-P10055
-
|
PSMA-1
|
PSMA
|
Cancer
|
|
PSMA-1 is a PSMA targeting peptide (GRFLTGGTGRLLRIS) and can be used for for targeted delivery of glucose-regulated protein (GRP)-silencing siRNAs in PCa cells. PSMA-1 is selected and polyarginine sequences R6 or R9 were added at the C terminus to generate the CTPs. FITC labeling of the peptide with an aminohexanoic acid (Ahx) linker at the N terminus produced FITC-PSMA-1, to track PSMA binding on PCa cells .
|
-
- HY-P10202A
-
|
|
STAT
|
Cancer
|
|
5-FAM-GpYLPQTV-NH2 (TFA) is a fluorescently labeled peptide and has STAT3 inhibitory activity. 5-FAM-GpYLPQTV-NH2 (TFA) can be used in cancer research .
|
-
- HY-147057
-
|
FAP-2286
|
FAP
|
Cancer
|
|
Rofapitide tetraxetan (FAP-2286) is a potent and selective FAP-binding peptide with a mean IC50 value of 2.7 nM for binding to FAP. Rofapitide tetraxetan can be labeled with radionuclides for diagnostic applications. Rofapitide tetraxetan has antitumor activity .
|
-
- HY-147057A
-
|
FAP-2286 acetate
|
FAP
|
Cancer
|
|
Rofapitide tetraxetan (FAP-2286) acetate is a potent and selective FAP-binding peptide with a mean IC50 value of 2.7 nM for binding to FAP. Rofapitide tetraxetan acetate can be labeled with radionuclides for diagnostic applications. Rofapitide tetraxetan acetate has antitumor activity .
|
-
- HY-P5378
-
|
Cathepsin S substrate
|
Ser/Thr Protease
|
Others
|
|
Ac-KQKLR-AMC (Cathepsin S substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.This peptide is a cathepsin S substrate fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). It can be used to measure cathepsin S activity.)
|
-
- HY-10235S
-
|
VX-950-d4
|
Isotope-Labeled Compounds
HCV Protease
HCV
SARS-CoV
|
Infection
|
|
Telaprevir-d4 is the deuterium labeled Telaprevir. Telaprevir (VX-950) is a highly selective, reversible, and potent peptidomimetic inhibitor of the HCV NS3-4A protease, the steady-state inhibitory constant (Ki) of Telaprevir is 7 nM against a genotype 1 (H strain) NS3 protease domain plus a NS4A cofactor peptide[1][2][3]. Telaprevir inhibits SARS-CoV-2 3CLpro activity[4].
|
-
- HY-P1047
-
|
[Pro18, Asp21] β-Amyloid (17-21)
|
Amyloid-β
|
Neurological Disease
|
|
β-Sheet Breaker Peptide iAβ5 is an effective brain amyloid-β (Abeta) degrader. Abeta deposits are associated with Alzheimer's disease (AD), and the related toxicity arises from its β-sheet conformation and aggregation. β-Sheet Breaker Peptide iAβ5 can repeatedly induce the degradation of fibrillary amyloid deposits in vivo. Therefore, β-Sheet Breaker Peptide iAβ5 can prevent and/or reverse neuronal contraction caused by Abeta and reduce the range of interleukin IL-1beta positive microglial-like cells around Abeta deposits. β-Sheet Breaker Peptide iAβ5 can reduce the size and/or number of brain amyloid plaques in AD. β-Sheet Breaker Peptide iAβ5 is labeled with a hydrophobic benzyl alcohol (HBA) tag and shows a bright blue color under acidic conditions, which can be used for quantitative determination.
|
-
- HY-14184S
-
-
- HY-153549
-
|
|
Radionuclide-Drug Conjugates (RDCs)
CXCR
|
Others
|
|
Pentixafor is a peptide that targets CXCR4. Pentixafor is capable of being labelled with 68Gallium ( 68Ga) for positron emission tomography (PET) imaging . Pentixafor can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
|
-
- HY-D1566
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-157414
-
|
|
Others
|
Others
|
|
Azide-A-DSBSO crosslinker is a mass spectrometry (MS)-cleavable, membrane-permeable, homobifunctional, azide-labeled, acid-cleavable cross-linked peptide. Azide-A-DSBSO crosslinker enables the study of protein-protein interactions via cross-linking mass spectrometry (XL-MS) .
|
-
- HY-Y0623
-
|
HOSu; 1-Hydroxy-2,5-pyrrolidinedione
|
Biochemical Assay Reagents
|
Others
|
|
N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is an activated ester commonly used in bioconjugation technologies such as protein labeling with fluorescent dyes and enzymes, chromatography supports, beads, nanoparticles, and microarrays Surface activation of glass slides, and chemically synthesized peptides .
|
-
- HY-P2551
-
|
|
Amyloid-β
|
Neurological Disease
|
|
Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-?-(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via?post-translational processing of amyloid precursor protein (APP) .
|
-
- HY-D1085
-
|
|
Fluorescent Dye
|
Others
|
|
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .
|
-
- HY-D1052
-
|
|
Fluorescent Dye
|
Cancer
|
|
Cy7-YNE is a fluorescence labeling agent (Ex=700-770 nm，Em=790 nm). Cyanine dyes are used to label proteins, antibodies, and peptides. Cy7-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-13631ES4
-
-
- HY-P1363F3
-
|
5-FAM-Amyloid β-peptide (1-42) (human) Tris
|
Amyloid-β
|
Neurological Disease
|
|
5-FAM-β-Amyloid (1-42), human (5-FAM-Amyloid β-peptide (1-42) (human) TFA is a5-FAM labeled β-Amyloid (1-42), human TFA (HY-P1363).
|
-
- HY-D2381
-
|
|
Fluorescent Dye
|
Others
|
|
AF 488 maleimide is a thiol-reactive dye for labeling of protein SH groups, and it can be used to attach AF 488 fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
-
- HY-13631ES
-
-
- HY-P5937
-
|
|
Apoptosis
|
Cancer
|
|
Caerin 1.1 TFA is a host defense peptide isolated from the glandular secretions of the Australian tree frog Litoria. Caerin 1.1 TFA inhibits HeLa cell proliferation and mediates apoptosis. Caerin 1.1 TFA may enhance adaptive T cell immune responses .
|
-
- HY-B0282S
-
|
ACh-d4 (chloride)
|
nAChR
Calcium Channel
Endogenous Metabolite
|
Neurological Disease
Cancer
|
|
Acetylcholine-d4 (chloride) is the deuterium labeled Acetylcholine chloride. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs)[1][2]. Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro[5].
|
-
- HY-B0282S1
-
|
ACh-d9(chloride)
|
nAChR
Calcium Channel
Endogenous Metabolite
|
Neurological Disease
Cancer
|
|
Acetylcholine-d9 (chloride) is the deuterium labeled Acetylcholine chloride. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs)[1][2]. Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro[5].
|
-
- HY-D1654
-
|
|
Fluorescent Dye
|
Others
|
|
BDP 581/591 maleimide is a linker of the BDP 581/591 dye. It has a long fluorescence lifetime and can be used for fluorescence polarization assays. The maleimide group can react with thiol groups to form thioester bonds between pH 6.5 to 7.5, for the labeling of sulfhydryl groups of proteins and peptides.
|
-
- HY-D1596
-
|
Cy3.5 NHS ester chloride; Cy 3.5 chloride
|
Fluorescent Dye
|
Others
|
|
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
-
- HY-B0239S3
-
|
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Chloramphenicol-d4 is deuterium labeled Chloramphenicol. Chloramphenicol, a broad-spectrum antibiotic, acts as a potent inhibitor of bacterial protein biosynthesis[1][2]. Chloramphenicol acts primarily on the 50S subunit of bacterial 70S rihosomes and inhibits peptide bond formation by suppressing peptidyl transferase activity[3].
|
-
- HY-P5296
-
|
|
Fluorescent Dye
|
Others
|
|
Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans is a fluorophore Dabsyl-labeled peptide. Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans can be used to test the peptidase activity of the LasA protease of Pseudomonas aeruginosa. Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans has enzyme specificity and has application value .
|
-
- HY-D0818
-
|
Sulfo-Cyanine3-alkyne
|
Fluorescent Dye
|
Others
|
|
CY3-YNE (Sulfo-Cyanine3-alkyne) is a dye for the labeling of soluble proteins, peptides, and oligonucleotides/DNA. CY3-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D2441
-
|
|
Fluorescent Dye
|
Cancer
|
|
TAT-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, Cell membrane penetrating peptide (TAT) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. TAT-PEG-Cy3 can be used for cell targeted delivery and biological imaging .
|
-
- HY-P2671
-
|
|
Cholecystokinin Receptor
|
Others
|
|
[Leu15]-Gastrin I (human) is a Leu15-labeled Gastrin I (human) peptide hormone, which is trophic for normal gastrointestinal epithelium. Gastrin stimulates growth of gastric adenocarcinoma (gastric cancer) through G-protein-coupled receptor called the cholecystokinin (CCK) or cholecystokinin-B receptors (CCK-BR) that are overexpressed in this malignancy. [Leu15]-Gastrin I (human) is promising for research of gastric cancer .
|
-
![[Leu15]-Gastrin I (human)](//file.medchemexpress.eu/product_pic/hy-p2671.gif)
- HY-D0820
-
|
Sulfo-Cyanine5-alkyne
|
Fluorescent Dye
|
Others
|
|
CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. CY5-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-Y1636S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Fmoc-Arg(Pbf)-OH- 13C6 is the 13C labeled Fmoc-Arg(Pbf)-OH[1]. Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis)[2].
|
-
- HY-D1596A
-
|
Cy3.5 NHS ester bromide; Cy 3.5 bromide
|
Fluorescent Dye
|
Others
|
|
Cyanine 3.5 bromide (Cy3.5 NHS ester bromide) is an analog of the Cy3.5 fluorophore. Cyanine 3.5 bromide is a red reactive fluorescent dye. Cyanine 3.5 bromide is used to label amino groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
-
- HY-D1794
-
|
VF 405 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 405 SE (VF 405 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=399 nm/421 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1791
-
|
VF 750 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 750 SE (VF 750 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=747 nm/770 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-P5297
-
|
|
Radionuclide-Drug Conjugates (RDCs)
CXCR
|
Cancer
|
|
DOTA-CXCR4-L is a CXCR4 targeting peptide. DOTA-CXCR4-L can be used in the study of cancers, including glioblastoma and triple-negative breast cancer. NODAGA-LM3 can be labeled with [68Ga]/[177Lu] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .
|
-
- HY-D1797
-
|
VF 660 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 660 SE (VF 660 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=660 nm/679 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-P10135
-
|
|
Endothelin Receptor
|
Cardiovascular Disease
|
|
RES-701-1 is a cyclic peptide composed of 16 common L-amino acids, acting as a specific antagonist for the ETB receptor. RES-701-1 can inhibit the binding of 125I-ET-1 (125I-labeled Endothelin (ET)-1) to the ETB receptor, with an IC50 value of 10 nM .
|
-
- HY-D1802
-
|
VF 425 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 425 SE (VF 425 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=430 nm/475 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1800
-
|
VF 680 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 680 SE (VF 680 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=680 nm/700 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1792
-
|
VF 555 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 555 SE (VF 555 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=550 nm/561 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1790
-
|
VF 640 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 640 SE (VF 640 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=648 nm/664 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1803
-
|
VF 565 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 565 SE (VF 565 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=563 nm/594 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1798
-
|
VF 350 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 350 SE (VF 350 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=350 nm/448 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1796
-
|
VF 594 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 594 SE (VF 594 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=585 nm/609 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1801
-
|
VF 488 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 488 SE (VF 488 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=488 nm/513 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1795
-
|
VF 532 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 532 SE (VF 532 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=532 nm/545 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1799
-
|
VF 568 SE
|
Fluorescent Dye
|
Others
|
|
Vari Fluor 568 SE (VF 568 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=573 nm/595 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-P4899
-
|
|
Beta-secretase
|
Neurological Disease
|
|
RE (EDANS) EVNLDAEFK (DABCYL) R is an EDANS and DABCYL double-labeled peptide，serves as a fluorescent substrate for BACE1(Em=360nm，Ex=528nm). RE (EDANS) EVNLDAEFK (DABCYL) R can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction .
|
-
- HY-155446
-
|
|
Others
|
Inflammation/Immunology
Cancer
|
|
di-DTPA-LTL is a bivalent hapten based on tyrosine-containing polypeptide design. di-DTPA-LTL has good hydrophilia and biological distribution. di-DTPA-LTL is labeled with 111In (indium) and 131I (iodine). di-DTPA-LTL achieves tumor radioimmunoimaging in primary colorectal cancer patients with CEA by injecting a fixed low dose (5 mg) of bispecific antibody (anti-CEA x, anti-DTPA) and di-DTPA antigen peptide (labeled 111In) into the patients .
|
-
- HY-147206
-
|
|
Fluorescent Dye
|
Others
|
|
Biotin-PEG-Alk (MW 600) is a Biotin-labeled Alkyne functionalized polyethylene glycol. Biotin-PEG-Alk (MW 600) can be used to modify proteins, peptides, and oligonucleotides . Biotin-PEG-Alk (MW 600) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-10119S
-
|
SCH 530348-d5
|
Protease Activated Receptor (PAR)
Isotope-Labeled Compounds
|
Cardiovascular Disease
|
|
Vorapaxar-d5 is deuterated labeled Vorapaxar (HY-10119). Vorapaxar (SCH 530348), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar (SCH 530348) inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner .
|
-
- HY-P10896
-
|
|
Bombesin Receptor
|
Cancer
|
|
NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT .
|
-
- HY-P5520
-
|
|
Bombesin Receptor
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
|
-
- HY-D1848
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
-
- HY-B0290S1
-
-
- HY-112295
-
|
|
Biochemical Assay Reagents
|
Infection
|
|
AzKTB is a capture reagent which bears a short trypsin-cleavable peptide sequence between the azide module and the TAMRA/PEG-biotin labels. AzKTB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-Y1169S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Fmoc-Asp(OtBu)-OH- 13C4, 15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[2].
|
-
- HY-W027544S
-
|
7-Methoxy-d3-2-oxo-2H-1-benzopyran-4-acetic acid; 7-Methoxy-d3-2H-chromen-2-one-4-acetic acid
|
Isotope-Labeled Compounds
|
Others
|
|
(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d3 is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3].
|
-
- HY-P10913
-
|
|
Bacterial
|
Infection
|
|
HYNIC-UBI29-41 is composed of a bifunctional chelator HYNIC and an antimicrobial peptide UBI 29-41. HYNIC-UBI29-41 retains the antibacterial properties of UBI 29-41, and exhibits good affinity to Gram-positive and Gram-negative bacteria. HYNIC-UBI29-41 can be used as an imaging agent for bacterial infection detection in mouse models, when labeled with the radioactive element technetium (99mTc) .
|
-
- HY-12366S
-
|
MK-1602-d5
|
Isotope-Labeled Compounds
CGRP Receptor
|
Cardiovascular Disease
Neurological Disease
|
|
Ubrogepant-d5 (MK-1602-d5) is deuterium labeled Ubrogepant. Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor (CGRP). Ubrogepant has high affinity for CGRP receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by α-CGRP. Ubrogepant can be used in the study of acute migraine .
|
-
- HY-P2185
-
|
|
MMP
|
Others
|
|
NFF-3, the peptide, is a selective MMP substrate. NFF-3 selectively binds to MMP-3 and MMP-10 to be hydrolyzed. NFF-3 is also cleaved by trypsin, hepatocyte growth factor activator, and factor Xa. Label NFF-3 with a CyDye pair, Cy3/Cy5Q, can produce fluorescence in cell assays to detect cell activity .
|
-
- HY-P2185A
-
|
|
MMP
|
Others
|
|
NFF-3 TFA, the peptide, is a selective MMP substrate. NFF-3 TFA selectively binds to MMP-3 and MMP-10 to be hydrolyzed. NFF-3 TFA is also cleaved by trypsin, hepatocyte growth factor activator, and factor Xa. Label NFF-3 TFA with a CyDye pair, Cy3/Cy5Q, can produce fluorescence in cell assays to detect cell activity .
|
-
- HY-P10131
-
|
|
Radionuclide-Drug Conjugates (RDCs)
FAP
|
Cancer
|
|
3BP-3940 is a highly potent and selective peptide inhibitor of FAP that targets cancer-associated fibroblasts (CAFs) in the tumor microenvironment. 3BP-3940 can be labeled with radionuclides (such as Ga-68) for precise tumor imaging or Lu-177 for the development of targeted anticancer technologies. 3BP-3940 accumulates in tumor lesions and can be used to diagnose and inhibit various solid cancers and CAFs-related diseases .
|
-
- HY-16992A
-
W-54011
5 Publications Verification
|
Complement System
Reactive Oxygen Species
|
Inflammation/Immunology
|
|
W-54011 is a potent and orally active non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils with a Ki value of 2.2 nM. W-54011 also inhibits C5a-induced intracellular Ca 2+ mobilization, chemotaxis, and generation of ROS in human neutrophils with IC50s of 3.1 nM, 2.7 nM, and 1.6 nM, respectively .
|
-
- HY-15306S
-
|
SB-497115-13C4
|
Thrombopoietin Receptor
Bacterial
Apoptosis
|
Infection
Cardiovascular Disease
Cancer
|
|
Eltrombopag- 13C4 (SB-497115- 13C4) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .
|
-
- HY-P5057B
-
|
|
Fluorescent Dye
Bacterial
|
Infection
|
|
5-FAM-Ahx-LL-37 TFA is a 5-FAM (HY-66022) labeled LL-37, human (HY-P1222). The carboxyfluorescein group is attached via a 6-carbon spacer, 6-Aminohexanoic acid (Ahx, HY-B0236). LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity .
|
-
- HY-W010712S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Fmoc-His(Trt)-OH- 15N3 is the 15N labeled Fmoc-His(Trt)-OH[1]. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].
|
-
- HY-P5057A
-
|
|
Fluorescent Dye
Bacterial
|
Infection
|
|
5-FAM-LL-37 TFA is the TFA salt form of 5-FAM-LL-37 (HY-P5057). 5-FAM-LL-37 TFA is a LL-37 peptide labeled with fluorescein, which retains the antibacterial and immunomodulatory activities of LL-37. 5-FAM-LL-37 TFA binds to the bacterial cell membrane, destroys the integrity of the membrane, and exhibits board-spectrum antibacterial efficacy .
|
-
- HY-Y1169S2
-
|
4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d3; Fmoc-L-Asp(OtBu)-OH-d3
|
Isotope-Labeled Compounds
Amino Acid Derivatives
|
Others
|
|
Fmoc-Asp(OtBu)-OH-d3 (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d3) is deuterium labeled Fmoc-Asp(OtBu)-OH. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
|
-
- HY-164576
-
|
NODA-Bz-SCN
|
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
NCS-MP-NODA (NODA-Bz-SCN) is a bifunctional chelator that can be used to bind to the labeled peptide DK222 with high specificity for PD-L1. The corresponding fluorinated radioactive is synthesized by the aluminum fluoride method, and NCS-MP-NODA targets DK222 to obtain the radioactive analog [18/19F]DK222. [18F]DK222 can quantify PD-L1 in vivo via PET tracking in xenograft models of multiple cancer types.
|
-
- HY-151711
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy5.5 Azide is a click chemistry reagent containing an azide group. Sulfo-Cy5.5 Azide is also a water-soluble dye (Ex=673 nm, Em=707 nm), which designed to label sensitive molecules such as peptides, proteins and oligonucleotides. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-D0098
-
|
N-(5-Fluoresceinyl)maleimide
|
Fluorescent Dye
|
Others
|
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
|
-
- HY-66019
-
FITC
Maximum Cited Publications
50 Publications Verification
Fluorescein 5-isothiocyanate
|
Fluorescent Dye
|
Inflammation/Immunology
|
|
FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
|
-
- HY-19210
-
|
|
Endothelin Receptor
|
Cardiovascular Disease
|
|
SB-209670 is an extremely potent and highly specific non-peptide, subnanomolar endothelin (ET) receptor antagonist. SB 209670 selectively inhibits binding of 125I-labeled ET-1 to cloned human ET receptor subtypes ETA and ETB (Ki=0.2 and 18 nM, respectively). SB 209670 produces a dose-dependent reduction in blood pressure in hypertensive rats, protects from ischemia-induced neuronal degeneration in a gerbil stroke model, and attenuates neointima formation following rat carotid artery balloon angioplasty .
|
-
- HY-W027544S1
-
|
5-(Dimethyl-d6-amino)-N-(prop-2-ynyl)naphthalene-1-sulfonamide
|
Isotope-Labeled Compounds
|
Others
|
|
(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3]. (7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-13948BS
-
|
Angiotensin II-13C6,15N TFA; Ang II-13C6,15N TFA; DRVY(I-13C6,15N)HPF TFA
|
Isotope-Labeled Compounds
|
Cancer
|
|
Angiotensin II human- 13C6, 15N TFA (Ang II- 13C6, 15N TFA) is 13C- and 15N-labeled Angiotensin II human (TFA) (HY-13948B). Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions .
|
-
- HY-163422S
-
-
- HY-P1032S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Angiotensin I- 13C19, 15N3 (human, mouse, rat) is the 13C and 15N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
|
-
- HY-159046S
-
-
- HY-159065S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
FIQE(Val- 13C5, 15N)NTTTR TFA is the 13C and 15N-labeled FIQE(Val)NTTTR. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
|
-
- HY-P1142S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
GLP-2(rat) (Ala- 13C3, 15N) is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
|
-
- HY-P2625S
-
|
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
GLP-2(3-33) (Leu- 13C6, 15N) is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
|
-
- HY-163423S
-
-
- HY-P0265AS
-
|
Amyloid Beta-peptide-15N (1-40) (human) TFA; Amyloid β-peptide-15N (1-40) (human) TFA
|
Amyloid-β
|
Neurological Disease
|
|
β-Amyloid- 15N (1-40) (TFA) is the 15N-labledβ-Amyloid (1-40) (TFA). β-Amyloid (1-40) is a primary protein in plaques found in the brains of patients with Alzheimer's disease[1].
|
-
- HY-163424S
-
-
- HY-P1363S
-
|
Amyloid β-peptide-15N (1-42) (human) TFA
|
Amyloid-β
|
Neurological Disease
|
|
β-Amyloid- 15N (1-42), human (TFA) is the 15N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease[1].
|
-
- HY-P2625S1
-
|
|
Isotope-Labeled Compounds
GCGR
|
Metabolic Disease
|
|
GLP-2(3-33) (Leu- 13C6, 15N) TFA is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
|
-
- HY-163426S
-
-
- HY-P5201S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
VTSEGAGLQLQK- 13C6, 15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .
|
-
- HY-163425S
-
-
- HY-159192S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
SADDNIKTPAE(Arg- 13C6, 15N4)LLGPLPPSADDNLKT (TFA) is the 13C and 15N labeled isotope of SADDNIKTPAE-LLGPLPPSADDNLKT (TFA) .
|
-
- HY-159064S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
DSPSAPVNVT(Val- 13C5, 15)R TFA is the 13C and 15N-labeled DSPSAPVNVT(Val)R. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
|
-
- HY-163992S
-
-
- HY-P1033S1
-
-
![[Pyr1]-Apelin-13, Pro(13C5,15N) TFA](//file.medchemexpress.eu/product_pic/hy-p1033s1.gif)
- HY-P1033S
-
-
![[Pyr1]-Apelin-13, Gly(15N) TFA](//file.medchemexpress.eu/product_pic/hy-p1033s.gif)
- HY-P1032S2
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Angiotensin I-13C6,15N (human, mouse, rat) TFA is 13C and 15N labeled Angiotensin I (human, mouse, rat) TFA. Angiotensin I-13C6,15N (human, mouse, rat) TFA is a precursor of angiotensin II and is cleaved into angiotensin II by angiotensin converting enzyme (ACE) .
|
-
- HY-163993S
-
-
- HY-P0014S2
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Liraglutide- 13C6, 15N (TFA)is the 13C and 15N labeledLiraglutide(HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
|
-
- HY-159193S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
DHATS(Leu- 13C6, 15N)PVTIPSAVST(Gly- 13C2, 15N)HTTPLPVTDT (TFA) is the 13C and 15N labeled isotope of DHATS-PVTIPSAVST-HTTPLPVTDT (TFA) .
|
-
- HY-163427S
-
-
- HY-P3207S
-
-
- HY-P1142S1
-
|
|
Isotope-Labeled Compounds
Apoptosis
|
Others
|
|
GLP-2(rat) (Ala- 13C3, 15N) TFA is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
|
-
- HY-P0090S
-
|
Salmon calcitonin-13C6,15N4 TFA
|
CGRP Receptor
|
Metabolic Disease
|
|
Calcitonin- 13C6, 15N4 (salmon) (Salmon calcitonin- 13C6, 15N4) TFA is 13C and 15N-labeled Calcitonin (salmon) (HY-P0090). Calcitonin (salmon) , a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption .
|
-
- HY-159191S
-
-
| Cat. No. |
Product Name |
Type |
-
- HY-W039519
-
|
|
Fluorescent Dyes/Probes
|
|
7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye with an excitation peak at 355 nm and an emission peak at 405 nm. 7-Methoxycoumarin-3-carboxylic acid can be used to label peptide .
|
-
- HY-15938
-
|
|
Fluorescent Dyes/Probes
|
|
5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates .
|
-
- HY-15940
-
|
5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers
|
Fluorescent Dyes/Probes
|
|
5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .
|
-
- HY-D0017
-
|
DNSCl
|
Protein Labeling
|
|
Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis .
|
-
- HY-114118F
-
|
|
Fluorescent Dyes/Probes
|
|
Semaglutide, FITC labeled is a FITC labeled Semaglutide. Semaglutide, a long-acting GLP-1 alogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide has the potential for type 2 diabetes treatment .
|
-
- HY-15944
-
|
5(6)-Carboxytetramethylrhodamine
|
Fluorescent Dyes/Probes
|
|
5(6)-TAMRA is a fluorescent dye molecule widely used as a label for peptides and proteins.
|
-
- HY-D1405
-
|
|
Protein Labeling
|
|
Br-5MP-Fluorescein is a dye reagent for labeling of peptides and proteins .
|
-
- HY-114350
-
|
|
Fluorescent Dyes/Probes
|
|
BDP FL maleimide is a thiol-reactive dye (Ex: 503 nm; Em: 509 nm). BDP FL maleimide can be used for protein labeling, peptide modification, and can replace fluorescein (FAM) for microscopy .
|
-
- HY-D1081
-
-
- HY-D2495
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7 SE (nosulfo) is a fluorescent dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides.
|
-
- HY-135414
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
-
- HY-D0819A
-
|
Cy5 NHS Ester triethylamine salt; Sulfo-Cyanine5 Succinimidyl Ester triethylamine salt
|
Fluorescent Dyes/Probes
|
|
Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm) .
|
-
- HY-D0819
-
|
Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester
|
Fluorescent Dyes/Probes
|
|
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.
Excitation (nm):649, Emission (nm): 670.
|
-
- HY-135414B
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .
|
-
- HY-D2290
-
|
|
Fluorescent Dyes/Probes
|
|
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .
|
-
- HY-D1618
-
|
|
Dyes
|
|
Cyanine3 maleimide tetrafluoroborate is a specific labeling reagent for sulfhydryl groups with the λex of 550 nm and λem of 580 nm. Cyanine3 maleimide tetrafluoroborate can be used for protein and peptide labeling .
|
-
- HY-D1849
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.
|
-
- HY-135414A
-
|
|
Fluorescent Dyes/Probes
|
|
Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues .
|
-
- HY-D2498
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .
|
-
- HY-D2439
-
|
|
Fluorescent Dyes/Probes
|
|
RGD-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, peptide (RGD) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. RGD is a peptide sequence (CRGDKGPDCiRGD) that binds to αvβ3 and αvβ5 integrin receptors on tumor neovasculogenesis to achieve specific tumor tissue targeting .
|
-
- HY-P1362FA
-
|
Cy5-Amyloid β peptide (42-1)(human) Tris
|
Fluorescent Dyes/Probes
|
|
Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λex= 633 nm and λem= 670 nm) .
|
-
- HY-P0136AF
-
|
|
Dyes
|
|
FAM-SAMS TFA is a 5-FAM (HY-66022) labeled SAMS (HY-P0136). SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK) .
|
-
- HY-D2488
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo Cy5.5-maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides.
|
-
- HY-P1362F
-
|
Cy5-Amyloid β peptide (42-1)(human)
|
Fluorescent Dyes/Probes
|
|
Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λex= 633 nm and λem= 670 nm) .
|
-
- HY-D1756
-
|
|
Fluorescent Dyes/Probes
|
|
ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer.
|
-
- HY-W879234
-
|
Sulfo Cy5.5-DBCO
|
Fluorescent Dyes/Probes
|
|
TriSulfo-Cy5.5 DBCO is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.TriSulfo-Cy5.5 DBCO can be used to label proteins, antibodies, peptides, nucleic acid molecules.
|
-
- HY-66022
-
5-FAM
3 Publications Verification
5-Carboxyfluorescein
|
Fluorescent Dyes/Probes
|
|
5-FAM (5-Carboxyfluorescein) is a green fluorescent reagent used for in situ labeling peptides, proteins and nucleotides. 5-FAM is a single isomer with Ex/Em of 490 nm/520 nm .
|
-
- HY-149117
-
|
|
Fluorescent Dyes/Probes
|
|
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-D1566
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-D1085
-
|
|
Fluorescent Dyes/Probes
|
|
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .
|
-
- HY-D1052
-
|
|
Fluorescent Dyes/Probes
|
|
Cy7-YNE is a fluorescence labeling agent (Ex=700-770 nm，Em=790 nm). Cyanine dyes are used to label proteins, antibodies, and peptides. Cy7-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-P1363F3
-
|
5-FAM-Amyloid β-peptide (1-42) (human) Tris
|
Fluorescent Dyes/Probes
|
|
5-FAM-β-Amyloid (1-42), human (5-FAM-Amyloid β-peptide (1-42) (human) TFA is a5-FAM labeled β-Amyloid (1-42), human TFA (HY-P1363).
|
-
- HY-D2381
-
|
|
Fluorescent Dyes/Probes
|
|
AF 488 maleimide is a thiol-reactive dye for labeling of protein SH groups, and it can be used to attach AF 488 fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
|
-
- HY-D1654
-
|
|
Fluorescent Dyes/Probes
|
|
BDP 581/591 maleimide is a linker of the BDP 581/591 dye. It has a long fluorescence lifetime and can be used for fluorescence polarization assays. The maleimide group can react with thiol groups to form thioester bonds between pH 6.5 to 7.5, for the labeling of sulfhydryl groups of proteins and peptides.
|
-
- HY-D1596
-
|
Cy3.5 NHS ester chloride; Cy 3.5 chloride
|
Fluorescent Dyes/Probes
|
|
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
-
- HY-D0818
-
|
Sulfo-Cyanine3-alkyne
|
Protein Labeling
|
|
CY3-YNE (Sulfo-Cyanine3-alkyne) is a dye for the labeling of soluble proteins, peptides, and oligonucleotides/DNA. CY3-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D2441
-
|
|
Fluorescent Dyes/Probes
|
|
TAT-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, Cell membrane penetrating peptide (TAT) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. TAT-PEG-Cy3 can be used for cell targeted delivery and biological imaging .
|
-
- HY-D0820
-
|
Sulfo-Cyanine5-alkyne
|
Protein Labeling
|
|
CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. CY5-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-D1596A
-
|
Cy3.5 NHS ester bromide; Cy 3.5 bromide
|
Fluorescent Dyes/Probes
|
|
Cyanine 3.5 bromide (Cy3.5 NHS ester bromide) is an analog of the Cy3.5 fluorophore. Cyanine 3.5 bromide is a red reactive fluorescent dye. Cyanine 3.5 bromide is used to label amino groups in peptides, proteins, and oligonucleotides. (λex=591 nm, λem=604 nm) .
|
-
- HY-D1794
-
|
VF 405 SE
|
Dyes
|
|
Vari Fluor 405 SE (VF 405 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=399 nm/421 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1791
-
|
VF 750 SE
|
Dyes
|
|
Vari Fluor 750 SE (VF 750 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=747 nm/770 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1797
-
|
VF 660 SE
|
Dyes
|
|
Vari Fluor 660 SE (VF 660 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=660 nm/679 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1802
-
|
VF 425 SE
|
Dyes
|
|
Vari Fluor 425 SE (VF 425 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=430 nm/475 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1800
-
|
VF 680 SE
|
Fluorescent Dyes/Probes
|
|
Vari Fluor 680 SE (VF 680 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=680 nm/700 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1792
-
|
VF 555 SE
|
Dyes
|
|
Vari Fluor 555 SE (VF 555 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=550 nm/561 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1790
-
|
VF 640 SE
|
Dyes
|
|
Vari Fluor 640 SE (VF 640 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=648 nm/664 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1803
-
|
VF 565 SE
|
Dyes
|
|
Vari Fluor 565 SE (VF 565 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=563 nm/594 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1798
-
|
VF 350 SE
|
Dyes
|
|
Vari Fluor 350 SE (VF 350 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=350 nm/448 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1796
-
|
VF 594 SE
|
Dyes
|
|
Vari Fluor 594 SE (VF 594 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=585 nm/609 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
-
- HY-D1801
-
|
VF 488 SE
|
Dyes
|
|
Vari Fluor 488 SE (VF 488 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=488 nm/513 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1795
-
|
VF 532 SE
|
Dyes
|
|
Vari Fluor 532 SE (VF 532 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=532 nm/545 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1799
-
|
VF 568 SE
|
Dyes
|
|
Vari Fluor 568 SE (VF 568 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=573 nm/595 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
|
- HY-D1848
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
- HY-P2185
-
|
|
Dyes
|
|
NFF-3, the peptide, is a selective MMP substrate. NFF-3 selectively binds to MMP-3 and MMP-10 to be hydrolyzed. NFF-3 is also cleaved by trypsin, hepatocyte growth factor activator, and factor Xa. Label NFF-3 with a CyDye pair, Cy3/Cy5Q, can produce fluorescence in cell assays to detect cell activity .
|
- HY-151711
-
|
|
Fluorescent Dyes/Probes
|
|
Sulfo-Cy5.5 Azide is a click chemistry reagent containing an azide group. Sulfo-Cy5.5 Azide is also a water-soluble dye (Ex=673 nm, Em=707 nm), which designed to label sensitive molecules such as peptides, proteins and oligonucleotides. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
- HY-D0098
-
|
N-(5-Fluoresceinyl)maleimide
|
Fluorescent Dyes/Probes
|
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
|
- HY-66019
-
FITC
Maximum Cited Publications
50 Publications Verification
Fluorescein 5-isothiocyanate
|
Fluorescent Dyes/Probes
|
|
FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
|
| Cat. No. |
Product Name |
Type |
-
- HY-W539893
-
|
NODAG
|
Chelators
|
|
NODAGA-tris(t-Bu ester) (NODAG) is a NODAGA derivative. NODAGA-tris(t-Bu ester) can be used to label peptides, antibodies, etc., and subsequently radiolabeled for PET imaging .
|
-
- HY-Y0623
-
|
HOSu; 1-Hydroxy-2,5-pyrrolidinedione
|
Biochemical Assay Reagents
|
|
N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is an activated ester commonly used in bioconjugation technologies such as protein labeling with fluorescent dyes and enzymes, chromatography supports, beads, nanoparticles, and microarrays Surface activation of glass slides, and chemically synthesized peptides .
|
-
- HY-156144
-
|
DBB chloride
|
Gene Sequencing and Synthesis
|
|
p-Diazobenzoyl-biocytin chloride is a biotin derivative that can be used for the labeling of tyrosine and histidines in peptides and proteins .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P0014S1
-
|
|
Isotope-Labeled Compounds
GLP Receptor
GCGR
|
Others
|
|
Liraglutide- 13C5, 15N (tetraTFA) is the 13C and 15N labeled Liraglutide (HY-P0014) . Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
|
-
- HY-P4138
-
|
|
Fluorescent Dye
|
Cancer
|
|
Antennapedia Peptide FAM-labeled is a fluorophore labeled peptide. Antennapedia Peptide FAM-labeled also can be used for the research of cancer as a molecular probe .
|
-
- HY-P5915
-
|
|
HIF/HIF Prolyl-Hydroxylase
|
Cancer
|
|
FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2, a 5-FAM labeled HIF-1α peptide, is a substrate of VHL. FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2 binds to VHL protein with a KD of 3 nM. Ex/Em (λ) = 485/520 nm .
|
-
- HY-P0014AS
-
-
- HY-P10292
-
-
- HY-156341S1
-
-
- HY-156345S1
-
-
- HY-156344S1
-
-
- HY-156343S1
-
-
- HY-P5969
-
-
- HY-P6424S
-
-
- HY-P6421S
-
-
- HY-P6423S
-
-
- HY-P6425S
-
-
- HY-P6422S
-
-
- HY-P2504
-
|
|
Syk
|
Others
|
|
Syk Kinase Peptide Substrate, Biotin labeled is a biotin-labled Syk kinase peptide substrate.
|
-
- HY-P5433F
-
|
|
Insulin Receptor
|
Others
|
|
IRS-1 Peptide, FAM labeled is a biological active peptide. (Insulin receptor substrate)
|
-
- HY-P3616
-
|
|
GCGR
|
Metabolic Disease
|
|
Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide is a biotin labeled glucagon-like peptide-1-(7-36). Glucagon-like peptide-1-(7-36) is a gastrointestinal peptide with antidiabetogenic activity, and can increase the release of insulin .
|
-
- HY-P1459
-
|
|
Bacterial
|
Infection
|
|
Sphistin Synthetic Peptide (12-38, Fitc in N-Terminal-Fluorescently Labeled Peptide) is a truncated fragments of Sphistin Synthetic Peptide that shows potent antimicrobial activity.
|
-
- HY-P4083
-
|
|
Fluorescent Dye
|
Others
|
|
(Arg)9,TAMRA-labeled is a TAMRA-labeled cell permeable peptide. (Arg)9 is a cell-permeable peptide used for drug delivery .
|
-
- HY-P5325F
-
|
|
Bcl-2 Family
|
Others
|
|
Bid BH3 (80-99), FAM labeled is a biological active peptide. (This is a 5-FAM-labeled Bid BH3 HY-P5325 peptide.)
|
-
- HY-P4135
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-LC-Antennapedia Peptide is a FITC labeled Antennapedia Peptide (HY-P0307). Antennapedia Peptide is a cellular-membrane permeable peptides (CPP). FITC-LC-Antennapedia Peptide has good penetration in 3T3 cell line, which was rapidly accumulated into nuclei .
|
-
- HY-P0248F
-
|
|
PKA
Fluorescent Dye
|
Others
|
|
Kemptide, 5-FAM labeled is a biological active peptide. (Kemptide is a phosphate acceptor peptide that serves as a synthetic substrate for PKA (Km = 16 μM). The corresponding fluorescent and biotinylated peptides are also proven to be good substrates for PKA. 5-FAM labeled HY-P0248)
|
-
- HY-158992S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
SP-(Val- 13C5, 15)-EKNQ-(Leu- 13C6, 15)-TIDFINIVKDPVPHNEYKT TFA is a 13C- and 15N-labeled peptide containing 13C5, 15N-labeled valine (Val) and 13C6, 15N-labeled leucine (Leu).
|
-
- HY-P10900
-
|
|
Peptides
|
Others
|
|
2x HA tag peptide is a tag peptide (YPYDVPDYAYPYDVPDYA) with a hemagglutinin HA tag. 2x HA tag peptide is often used to be fused to the 5' end of the target protein to label the protein .
|
-
- HY-P4105
-
-
- HY-158994S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
MEGDSRGG-(Ala- 13C3, 15N)-GGEA-(Leu- 13C6, 15N)-DPESAASSLSGAS TFA is a 13C- and 15N-labeled peptide containing 13C3, 15N-labeled alanine (Ala) and 13C6, 15N-labeled leucine (Leu).
|
-
- HY-P0030
-
-
- HY-P2292
-
|
|
Bacterial
Fungal
|
Infection
|
|
Omiganan, FITC labeled is a peptide-FITC complex composed of Omiganan and a FITC. Omiganan is a bactericidal and fungicidal cationic peptide being developed as a topical gel for prevention of catheter-associated infections. FITC is a derivative of fluorescein for the labeling of amines .
|
-
- HY-13443F
-
|
|
GCGR
|
Others
|
|
Exendin 4, biotin labeled is a biological active peptide. (Biotin labeled HY-13443)
|
-
- HY-P5438F
-
|
|
Peptides
|
Others
|
|
FAM-Srctide is a biological active peptide. (FAM labeled Srctide)
|
-
- HY-P0201F
-
-
- HY-P10183
-
-
- HY-114118F
-
|
|
GCGR
|
Metabolic Disease
|
|
Semaglutide, FITC labeled is a FITC labeled Semaglutide. Semaglutide, a long-acting GLP-1 alogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide has the potential for type 2 diabetes treatment .
|
-
- HY-P0082F
-
|
|
Fluorescent Dye
|
Others
|
|
Glucagon (1-29), FAM-labeled is a biological active peptide. (FAM labeled HY-P0082)
|
-
- HY-P1755F
-
-
- HY-P2491
-
|
|
Fluorescent Dye
|
Cardiovascular Disease
Endocrinology
|
|
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .
|
-
- HY-P4125
-
|
|
HIV
|
Others
|
|
FITC-LC-TAT (47-57) is a FITC labeled TAT peptide. TAT is a cell-penetrating peptide (CPP). TAT can increase the yields and the solubility of heterologous proteins .
|
-
- HY-P2609F
-
|
|
PACAP Receptor
|
Others
|
|
PACAP (1-38), amide, Biotin-labeled is a biological active peptide. (Biotin-labeled HY-P0221)
|
-
- HY-P3146S
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
FTISADTSK- 13C6, 15N2 TFA is 13C- and 15N-labeled FTISADTSK (HY-P3146). FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM) .
|
-
- HY-P4337
-
-
- HY-P0300F
-
-
- HY-P2292A
-
|
|
Bacterial
Fungal
|
Infection
|
|
Omiganan, FITC labeled TFA is a peptide-FITC complex composed of Omiganan and a FITC. Omiganan is a bactericidal and fungicidal cationic peptide being developed as a topical gel for prevention of catheter-associated infections .
|
-
- HY-P4103
-
-
- HY-P0206F
-
-
- HY-P4337A
-
-
- HY-13948F1
-
|
Angiotensin II, FAM-labeled ; Ang II, FAM-labeled ; DRVYIHPF, FAM-labeled
|
Angiotensin Receptor
|
Others
|
|
Angiotensin II human, FAM-labeled (Angiotensin II, FAM-labeled ; Ang II, FAM-labeled ; DRVYIHPF, FAM-labeled) is a biological active peptide. (FAM labeled HY-13948)
|
-
- HY-P5351
-
|
|
Peptides
|
Others
|
|
Hyaluronan-binding peptide, biotin labeled is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.)
|
-
- HY-P5351A
-
|
|
Transmembrane Glycoprotein
|
Inflammation/Immunology
Cancer
|
|
Hyaluronan-binding peptide, biotin labeled TFA is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.) .
|
-
- HY-P5119
-
|
|
Peptides
|
Neurological Disease
|
|
Tat-peptide 168-189 is a cell-permeable and Tat-labeled fusion peptide, corresponding to residues 168-189 of rat G3BP1. Tat sequence from HIV, is placed at the least conserved end of the sequence, for cell permeability. Tat-peptide 168-189 is the negtive control of Tat-peptide 190-208 (HY-P5118), as Tat-peptide 190-208 increases axon growth and increases the number of neurites per neuron .
|
- HY-P5119A
-
|
|
Peptides
|
Neurological Disease
|
|
Tat-peptide 168-189 is a cell-permeable and Tat-labeled fusion peptide, corresponding to residues 168-189 of rat G3BP1. Tat sequence from HIV, is placed at the least conserved end of the sequence, for cell permeability. Tat-peptide 168-189 is the negtive control of Tat-peptide 168-189 TFA (HY-P5118A), as Tat-peptide 168-189 TFA increases axon growth and increases the number of neurites per neuron .
|
- HY-P10184
-
|
|
Transmembrane Glycoprotein
|
Inflammation/Immunology
|
|
CD36 Peptide P (93-110), Cys conjugated is a Cys labelled CD36 Peptide, and can block binding of CD36 to immobilized thrombospondin and partially inhibited collagen-induced platelet aggregation .
|
- HY-P3432
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .
|
- HY-P1489F
-
|
|
Peptides
|
Others
|
|
FAM-OVA (257-264) is a biological active peptide. (FAM labeled HY-P1489)
|
- HY-P0286F1
-
- HY-P0286F
-
|
|
Peptides
|
Others
|
|
Biotin-OVA (323-339) is a biological active peptide. (Biotin labeled HY-P0286)
|
- HY-P5168S
-
|
|
Isotope-Labeled Compounds
SARS-CoV
|
Infection
|
|
GPSVFPLAPSSK- 13C6, 15N2 is the 13C- and 15N-labeled GPSVFPLAPSSK. GPSVFPLAPSSK is an IgG1 signature peptide of anti-SARS-CoV-2 antibodies. GPSVFPLAPSSK can be used for the quantification of the specific isolation of anti-SARS-CoV-2 antibodies .
|
- HY-P5168AS
-
|
|
Isotope-Labeled Compounds
SARS-CoV
|
Infection
|
|
GPSVFPLAPSSK- 13C6, 15N2 TFA is the 13C- and 15N-labeled GPSVFPLAPSSK. GPSVFPLAPSSK is an IgG1 signature peptide of anti-SARS-CoV-2 antibodies. GPSVFPLAPSSK can be used for the quantification of the specific isolation of anti-SARS-CoV-2 antibodies .
|
- HY-P5118
-
|
|
Peptides
|
Neurological Disease
|
|
Tat-peptide 190-208 is a cell-permeable and Tat-labeled fusion peptide, corresponding to residues 190-208 of rat G3BP1. Tat sequence from HIV, is placed at the least conserved end of the sequence, for cell permeability. Tat-peptide 190-208 increases axon growth and increases the number of neurites per neuron. Tat-peptide 190-208 likely exhibits an axon intrinsic mechanism. Tat-peptide 190-208 can be used for ischemic protection during endovascular repair for intracranial aneurysms .
|
- HY-P2496
-
|
|
Endothelin Receptor
|
Cardiovascular Disease
|
|
Endothelin 1 (swine, human), Alexa Fluor 488-labeled is a synthetic Endothelin 1 peptide labled with Alexa Fluor 488. Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB .
|
- HY-P4122
-
|
|
HIV
|
Others
|
|
TAT (47-57), FAM-labeled is a cell-penetrating peptide (CPP). TAT (47-57), FAM-labeled has the potential for intracellular drug delivery research .
|
- HY-P2550A
-
|
|
Amyloid-β
|
Neurological Disease
|
|
β-Amyloid (1-40), FAM-labeled TFA is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λex= 492 nm and λem= 518 nm).
|
- HY-106244A
-
|
|
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) . DOTATATE (acetate) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
|
- HY-106244
-
|
|
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) . DOTATATE can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
|
- HY-P2549
-
- HY-P0286F1A
-
- HY-P5118A
-
|
|
Peptides
|
Neurological Disease
|
|
Tat-peptide 190-208 TFA is a cell-permeable and Tat-labeled fusion peptide, corresponding to residues 190-208 of rat G3BP1. Tat sequence from HIV, is placed at the least conserved end of the sequence, for cell permeability. Tat-peptide 190-208 TFA increases axon growth and increases the number of neurites per neuron. Tat-peptide 190-208 TFA likely exhibits an axon intrinsic mechanism. Tat-peptide 190-208 TFA can be used for ischemic protection during endovascular repair for intracranial aneurysms .
|
- HY-P4154
-
|
ALM-488
|
Fluorescent Dye
|
Neurological Disease
Cancer
|
|
Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .
|
- HY-P1097F
-
- HY-P2550
-
|
|
Amyloid-β
|
Neurological Disease
|
|
β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled?β-Amyloid (1-40) peptide (λex=?492?nm and λem=?518?nm) .
|
- HY-P4078
-
|
|
Peptides
|
Others
|
|
(Arg)9 biotin labeled is a cell-permeable peptide. (Arg)9 biotin labeled can be used for drug delivery. (Arg)9 biotin labeled can traverse the plasma membrane of eukaryotic cells .
|
- HY-P2500
-
|
|
Fluorescent Dye
|
Others
|
|
(Arg)9, FAM-labeled, a cell-penetrating peptide (CPP), is a nona-arginine (ARG) with FAM label. CPPs have emerged as powerful tools for delivering bioactive cargoes into the cytosol of intact cells .
|
- HY-P5323
-
|
|
Peptides
|
Others
|
|
Dabcyl-AGHDAHASET-Edans is a biological active peptide. (This is a type I signal peptidase (SPase1) substrate peptide labeled with EDANS/ DABCYL FRET pair, and contains a crucial cleavage site derived from the C-terminal region of the Staphylococcus epidermidis pre-SceD protein. Abs/Em = 340/490 nm.)
|
- HY-17571F
-
|
Biotin-α-Hypophamine; Biotin-Oxytocic hormone
|
Oxytocin Receptor
|
Others
|
|
Biotin-Oxytocin (Biotin-α-Hypophamine; Biotin-Oxytocic hormone) is a biological active peptide. (This is Oxytocin (HY-17571) N-terminally labeled with Biotin.)
|
- HY-P10792
-
|
|
EGFR
|
Cancer
|
|
HER2-targeted peptide H6F is a HER2 targeting peptide that binds to HER2 to target breast cancer cells, with the amino acid sequence YLFFVFER. The HER2-targeted peptide H6F can be conjugated with the bifunctional chelating agent hydrazinonicotinamide (HYNIC) for radiolabeling with 99mTc. Single-photon emission computed tomography (SPECT) imaging shows that the labeled HER2-targeted peptide H6F specifically accumulates in HER2-positive MDA-MBA-453 tumor-bearing mice models. The HER2-targeted peptide H6F can be used for tumor molecular imaging studies .
|
- HY-P0136F
-
|
|
AMPK
|
Others
|
|
FAM-SAMS is a 5-FAM (HY-66022) labeled SAMS (HY-P0136). SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK) .
|
- HY-P2535
-
|
|
GLP Receptor
|
Metabolic Disease
|
|
Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human is an C-terminal-labelled biotinylated GLP-1 (7-36) amide.
|
- HY-13948F
-
|
Biotin-Ahx-Angiotensin II; Biotin-Ahx-Ang II; Biotin-Ahx-DRVYIHPF
|
Angiotensin Receptor
|
Others
|
|
Biotin-Ahx-Angiotensin II human (Biotin-Ahx-Angiotensin II; Biotin-Ahx-Ang II; Biotin-Ahx-DRVYIHPF) is a biological active peptide. (biotin labeled HY-13948)
|
- HY-P0136AF
-
|
|
Fluorescent Dye
|
Others
|
|
FAM-SAMS TFA is a 5-FAM (HY-66022) labeled SAMS (HY-P0136). SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK) .
|
- HY-P1363F1
-
|
Biotin-amyloid β-peptide (1-42) (human) TFA
|
Amyloid-β
|
Neurological Disease
|
|
Biotin-β-Amyloid (1-42), human TFA (Biotin-Amyloid β-Peptide (1-42) (human) TFA) is the botin labeled β-Amyloid (1-42), human TFA (HY-P1363). β-Amyloid (1-42), human TFA is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease .
|
- HY-P5527F
-
|
|
Peptides
|
Others
|
|
FAM-CSKtide is a biological active peptide. (This is a FAM labeled peptide substrate (Abs/Em = 494/521 nm) for C-terminal Src kinase (Csk) and many other kinases such as Axl, cKit, ERBB4, Fes, Flt3, IGF-1 R, MET, MUSK, PYK2, Ret, TIE2, TrkA, VEGF-R1 and VEGF-R2.)
|
- HY-P1032F
-
|
|
Endogenous Metabolite
|
Endocrinology
|
|
Biotinyl-Angiotensin I (human, mouse, rat) is biotin-labeled Angiotensin I . Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE) .
|
- HY-P2499
-
|
|
Bcl-2 Family
|
Cancer
|
|
BAD (103-127) (human), FAM-labeled is a FAM-labeled human BAD (103-127) (HY-P2468). BAD (103-127) (human), the 25-mer Bad peptide, is derived from the BH3 domain of BAD, can antagonize the function of Bcl-xL .
|
- HY-P10202
-
|
|
STAT
|
Cancer
|
|
5-FAM-GpYLPQTV-NH2 is a fluorescently labeled peptide and has STAT3 inhibitory activity. 5-FAM-GpYLPQTV-NH2 can be used in cancer research .
|
- HY-P5367
-
|
PMDM6-F
|
Fluorescent Dye
|
Others
|
|
5-FAM-PMDM6 (PMDM6-F) is a biological active peptide. (PMDM6-F is a fluorescent-labeled probe for MDM2-binding assay.)
|
- HY-P5508
-
|
|
Peptides
|
Others
|
|
MUC5AC-13 is a biological active peptide. (This glycopeptide is an N-acetyl galactosamine (GalNAc)-modified MUC5AC mucin peptide containing the single site of threonine 13 labeled with GalNAc (T*). Polypeptide N-acetylgalactosaminyltransferase (ppGaNTase) catalyzes the transfer of GalNAc from the nucleotide sugar UDP-GalNAc to threonine. The MUC5AC gene is mainly expressed in gastric and tracheo-bronchial mucosae, and some tumors.)
|
- HY-P10055
-
|
PSMA-1
|
PSMA
|
Cancer
|
|
PSMA-1 is a PSMA targeting peptide (GRFLTGGTGRLLRIS) and can be used for for targeted delivery of glucose-regulated protein (GRP)-silencing siRNAs in PCa cells. PSMA-1 is selected and polyarginine sequences R6 or R9 were added at the C terminus to generate the CTPs. FITC labeling of the peptide with an aminohexanoic acid (Ahx) linker at the N terminus produced FITC-PSMA-1, to track PSMA binding on PCa cells .
|
- HY-P10202A
-
|
|
STAT
|
Cancer
|
|
5-FAM-GpYLPQTV-NH2 (TFA) is a fluorescently labeled peptide and has STAT3 inhibitory activity. 5-FAM-GpYLPQTV-NH2 (TFA) can be used in cancer research .
|
- HY-P5378
-
|
Cathepsin S substrate
|
Ser/Thr Protease
|
Others
|
|
Ac-KQKLR-AMC (Cathepsin S substrate) is a biological active peptide. (Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis, cancer, obesity and related diseases.This peptide is a cathepsin S substrate fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). It can be used to measure cathepsin S activity.)
|
- HY-P1047
-
|
[Pro18, Asp21] β-Amyloid (17-21)
|
Amyloid-β
|
Neurological Disease
|
|
β-Sheet Breaker Peptide iAβ5 is an effective brain amyloid-β (Abeta) degrader. Abeta deposits are associated with Alzheimer's disease (AD), and the related toxicity arises from its β-sheet conformation and aggregation. β-Sheet Breaker Peptide iAβ5 can repeatedly induce the degradation of fibrillary amyloid deposits in vivo. Therefore, β-Sheet Breaker Peptide iAβ5 can prevent and/or reverse neuronal contraction caused by Abeta and reduce the range of interleukin IL-1beta positive microglial-like cells around Abeta deposits. β-Sheet Breaker Peptide iAβ5 can reduce the size and/or number of brain amyloid plaques in AD. β-Sheet Breaker Peptide iAβ5 is labeled with a hydrophobic benzyl alcohol (HBA) tag and shows a bright blue color under acidic conditions, which can be used for quantitative determination.
|
- HY-153549
-
|
|
Radionuclide-Drug Conjugates (RDCs)
CXCR
|
Others
|
|
Pentixafor is a peptide that targets CXCR4. Pentixafor is capable of being labelled with 68Gallium ( 68Ga) for positron emission tomography (PET) imaging . Pentixafor can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
|
- HY-P2551
-
|
|
Amyloid-β
|
Neurological Disease
|
|
Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-?-(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via?post-translational processing of amyloid precursor protein (APP) .
|
- HY-P1363F3
-
|
5-FAM-Amyloid β-peptide (1-42) (human) Tris
|
Amyloid-β
|
Neurological Disease
|
|
5-FAM-β-Amyloid (1-42), human (5-FAM-Amyloid β-peptide (1-42) (human) TFA is a5-FAM labeled β-Amyloid (1-42), human TFA (HY-P1363).
|
- HY-P5937
-
|
|
Apoptosis
|
Cancer
|
|
Caerin 1.1 TFA is a host defense peptide isolated from the glandular secretions of the Australian tree frog Litoria. Caerin 1.1 TFA inhibits HeLa cell proliferation and mediates apoptosis. Caerin 1.1 TFA may enhance adaptive T cell immune responses .
|
- HY-P5296
-
|
|
Fluorescent Dye
|
Others
|
|
Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans is a fluorophore Dabsyl-labeled peptide. Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans can be used to test the peptidase activity of the LasA protease of Pseudomonas aeruginosa. Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans has enzyme specificity and has application value .
|
- HY-P2671
-
|
|
Cholecystokinin Receptor
|
Others
|
|
[Leu15]-Gastrin I (human) is a Leu15-labeled Gastrin I (human) peptide hormone, which is trophic for normal gastrointestinal epithelium. Gastrin stimulates growth of gastric adenocarcinoma (gastric cancer) through G-protein-coupled receptor called the cholecystokinin (CCK) or cholecystokinin-B receptors (CCK-BR) that are overexpressed in this malignancy. [Leu15]-Gastrin I (human) is promising for research of gastric cancer .
|
- HY-P5297
-
|
|
Radionuclide-Drug Conjugates (RDCs)
CXCR
|
Cancer
|
|
DOTA-CXCR4-L is a CXCR4 targeting peptide. DOTA-CXCR4-L can be used in the study of cancers, including glioblastoma and triple-negative breast cancer. NODAGA-LM3 can be labeled with [68Ga]/[177Lu] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .
|
- HY-P10135
-
|
|
Endothelin Receptor
|
Cardiovascular Disease
|
|
RES-701-1 is a cyclic peptide composed of 16 common L-amino acids, acting as a specific antagonist for the ETB receptor. RES-701-1 can inhibit the binding of 125I-ET-1 (125I-labeled Endothelin (ET)-1) to the ETB receptor, with an IC50 value of 10 nM .
|
- HY-P4899
-
|
|
Beta-secretase
|
Neurological Disease
|
|
RE (EDANS) EVNLDAEFK (DABCYL) R is an EDANS and DABCYL double-labeled peptide，serves as a fluorescent substrate for BACE1(Em=360nm，Ex=528nm). RE (EDANS) EVNLDAEFK (DABCYL) R can be used for BACE1 activity measurement and the enzyme activity level is directly proportional to the fluorescence reaction .
|
- HY-P10896
-
|
|
Bombesin Receptor
|
Cancer
|
|
NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT .
|
- HY-P5520
-
|
|
Bombesin Receptor
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
GB-6 is a short linear peptide that targets the gastrin releasing peptide receptor (GRPR). GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor-specific accumulation properties of GB-6, GB-6 labeled with near infrared (NIR) fluorescent dyes or radionuclide netium-99m (99mTc) can be used as a high-contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in SW199 0 subcutaneous xenograft models. GB-6 can rapidly target tumors and accurately delineate tumor boundaries, which has broad application prospects .
|
- HY-P10913
-
|
|
Bacterial
|
Infection
|
|
HYNIC-UBI29-41 is composed of a bifunctional chelator HYNIC and an antimicrobial peptide UBI 29-41. HYNIC-UBI29-41 retains the antibacterial properties of UBI 29-41, and exhibits good affinity to Gram-positive and Gram-negative bacteria. HYNIC-UBI29-41 can be used as an imaging agent for bacterial infection detection in mouse models, when labeled with the radioactive element technetium (99mTc) .
|
- HY-P2185
-
|
|
MMP
|
Others
|
|
NFF-3, the peptide, is a selective MMP substrate. NFF-3 selectively binds to MMP-3 and MMP-10 to be hydrolyzed. NFF-3 is also cleaved by trypsin, hepatocyte growth factor activator, and factor Xa. Label NFF-3 with a CyDye pair, Cy3/Cy5Q, can produce fluorescence in cell assays to detect cell activity .
|
- HY-P2185A
-
|
|
MMP
|
Others
|
|
NFF-3 TFA, the peptide, is a selective MMP substrate. NFF-3 TFA selectively binds to MMP-3 and MMP-10 to be hydrolyzed. NFF-3 TFA is also cleaved by trypsin, hepatocyte growth factor activator, and factor Xa. Label NFF-3 TFA with a CyDye pair, Cy3/Cy5Q, can produce fluorescence in cell assays to detect cell activity .
|
- HY-P10131
-
|
|
Radionuclide-Drug Conjugates (RDCs)
FAP
|
Cancer
|
|
3BP-3940 is a highly potent and selective peptide inhibitor of FAP that targets cancer-associated fibroblasts (CAFs) in the tumor microenvironment. 3BP-3940 can be labeled with radionuclides (such as Ga-68) for precise tumor imaging or Lu-177 for the development of targeted anticancer technologies. 3BP-3940 accumulates in tumor lesions and can be used to diagnose and inhibit various solid cancers and CAFs-related diseases .
|
- HY-P5057B
-
|
|
Fluorescent Dye
Bacterial
|
Infection
|
|
5-FAM-Ahx-LL-37 TFA is a 5-FAM (HY-66022) labeled LL-37, human (HY-P1222). The carboxyfluorescein group is attached via a 6-carbon spacer, 6-Aminohexanoic acid (Ahx, HY-B0236). LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity .
|
- HY-P5057A
-
|
|
Fluorescent Dye
Bacterial
|
Infection
|
|
5-FAM-LL-37 TFA is the TFA salt form of 5-FAM-LL-37 (HY-P5057). 5-FAM-LL-37 TFA is a LL-37 peptide labeled with fluorescein, which retains the antibacterial and immunomodulatory activities of LL-37. 5-FAM-LL-37 TFA binds to the bacterial cell membrane, destroys the integrity of the membrane, and exhibits board-spectrum antibacterial efficacy .
|
- HY-163422S
-
- HY-P1032S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Angiotensin I- 13C19, 15N3 (human, mouse, rat) is the 13C and 15N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
|
- HY-P4229
-
|
|
Peptides
|
Others
|
|
([D8]Val7,10)-C-Peptide (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
- HY-159046S
-
- HY-159065S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
FIQE(Val- 13C5, 15N)NTTTR TFA is the 13C and 15N-labeled FIQE(Val)NTTTR. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
|
- HY-P1142S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
GLP-2(rat) (Ala- 13C3, 15N) is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
|
- HY-P2625S
-
|
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
GLP-2(3-33) (Leu- 13C6, 15N) is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
|
- HY-163423S
-
- HY-P0265AS
-
|
Amyloid Beta-peptide-15N (1-40) (human) TFA; Amyloid β-peptide-15N (1-40) (human) TFA
|
Amyloid-β
|
Neurological Disease
|
|
β-Amyloid- 15N (1-40) (TFA) is the 15N-labledβ-Amyloid (1-40) (TFA). β-Amyloid (1-40) is a primary protein in plaques found in the brains of patients with Alzheimer's disease[1].
|
- HY-163424S
-
- HY-P1363S
-
|
Amyloid β-peptide-15N (1-42) (human) TFA
|
Amyloid-β
|
Neurological Disease
|
|
β-Amyloid- 15N (1-42), human (TFA) is the 15N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease[1].
|
- HY-P2625S1
-
|
|
Isotope-Labeled Compounds
GCGR
|
Metabolic Disease
|
|
GLP-2(3-33) (Leu- 13C6, 15N) TFA is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
|
- HY-163426S
-
- HY-P5201S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
VTSEGAGLQLQK- 13C6, 15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .
|
- HY-163425S
-
- HY-159192S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
SADDNIKTPAE(Arg- 13C6, 15N4)LLGPLPPSADDNLKT (TFA) is the 13C and 15N labeled isotope of SADDNIKTPAE-LLGPLPPSADDNLKT (TFA) .
|
- HY-159064S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
DSPSAPVNVT(Val- 13C5, 15)R TFA is the 13C and 15N-labeled DSPSAPVNVT(Val)R. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
|
- HY-163992S
-
- HY-P1033S1
-
- HY-P1033S
-
- HY-P1032S2
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Angiotensin I-13C6,15N (human, mouse, rat) TFA is 13C and 15N labeled Angiotensin I (human, mouse, rat) TFA. Angiotensin I-13C6,15N (human, mouse, rat) TFA is a precursor of angiotensin II and is cleaved into angiotensin II by angiotensin converting enzyme (ACE) .
|
- HY-163993S
-
- HY-P0014S2
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Liraglutide- 13C6, 15N (TFA)is the 13C and 15N labeledLiraglutide(HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
|
- HY-P10324
-
|
p16INK4a peptide
|
Peptides
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Cancer
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TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex .
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- HY-159193S
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Isotope-Labeled Compounds
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Others
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DHATS(Leu- 13C6, 15N)PVTIPSAVST(Gly- 13C2, 15N)HTTPLPVTDT (TFA) is the 13C and 15N labeled isotope of DHATS-PVTIPSAVST-HTTPLPVTDT (TFA) .
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- HY-163427S
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- HY-P3207S
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- HY-P1142S1
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Isotope-Labeled Compounds
Apoptosis
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Others
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GLP-2(rat) (Ala- 13C3, 15N) TFA is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
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- HY-P0090S
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Salmon calcitonin-13C6,15N4 TFA
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CGRP Receptor
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Metabolic Disease
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Calcitonin- 13C6, 15N4 (salmon) (Salmon calcitonin- 13C6, 15N4) TFA is 13C and 15N-labeled Calcitonin (salmon) (HY-P0090). Calcitonin (salmon) , a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption .
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- HY-159191S
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-P0014S1
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Liraglutide- 13C5, 15N (tetraTFA) is the 13C and 15N labeled Liraglutide (HY-P0014) . Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
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- HY-P0014AS
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Liraglutide-d8 tetraTFA is deuterium labeled Liraglutide (HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the study of type 2 diabetes mellitus .
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-
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- HY-156341S1
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LLIYYTSSLHSGVPSR-(Arg- 13C6, 15N4) (TFA) is the peptide containing 13C- and 15N-labeled Arg.
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-
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- HY-156345S1
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LPFTFGQGTK-(Lys- 13C6, 15N2) TFA is the peptide containing 13C- and 15N-labeled Lys.
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-
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- HY-156344S1
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GLEWVAEIR-(Arg- 13C6, 15N4) (TFA) is the peptide containing 13C- and 15N-labeled Arg.
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-
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- HY-156343S1
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SNNYATHYAESVK-(Lys- 13C6, 15N2) (TFA) is the peptide containing 13C- and 15N-labeled Lys.
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-
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- HY-P6424S
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LGADMEDVCG-Arg( 13C6, 15N4) TFA is a peptide containing 13C6 and 15N4 labeled Arg .
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-
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- HY-P6421S
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LGPLVEQG-Arg( 13C6, 15N4) TFA is a peptide containing 13C6 and 15N4 labeled Arg .
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-
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- HY-P6423S
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CLAVYQAGA-Arg( 13C6, 15N4) TFA is a peptide containing 13C6 and 15N4 labeled Arg .
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-
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- HY-P6425S
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LCADMEDV-Arg( 13C6, 15N4) TFA is a peptide containing 13C6 and 15N4 labeled Arg .
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- HY-P6422S
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LAVYQAGA-Arg( 13C6, 15N4) TFA is a peptide containing 13C6 and 15N4 labeled Arg .
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-
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- HY-158992S
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SP-(Val- 13C5, 15)-EKNQ-(Leu- 13C6, 15)-TIDFINIVKDPVPHNEYKT TFA is a 13C- and 15N-labeled peptide containing 13C5, 15N-labeled valine (Val) and 13C6, 15N-labeled leucine (Leu).
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-
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- HY-158994S
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MEGDSRGG-(Ala- 13C3, 15N)-GGEA-(Leu- 13C6, 15N)-DPESAASSLSGAS TFA is a 13C- and 15N-labeled peptide containing 13C3, 15N-labeled alanine (Ala) and 13C6, 15N-labeled leucine (Leu).
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- HY-P3146S
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FTISADTSK- 13C6, 15N2 TFA is 13C- and 15N-labeled FTISADTSK (HY-P3146). FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM) .
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- HY-P5168S
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GPSVFPLAPSSK- 13C6, 15N2 is the 13C- and 15N-labeled GPSVFPLAPSSK. GPSVFPLAPSSK is an IgG1 signature peptide of anti-SARS-CoV-2 antibodies. GPSVFPLAPSSK can be used for the quantification of the specific isolation of anti-SARS-CoV-2 antibodies .
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-
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- HY-P5168AS
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GPSVFPLAPSSK- 13C6, 15N2 TFA is the 13C- and 15N-labeled GPSVFPLAPSSK. GPSVFPLAPSSK is an IgG1 signature peptide of anti-SARS-CoV-2 antibodies. GPSVFPLAPSSK can be used for the quantification of the specific isolation of anti-SARS-CoV-2 antibodies .
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-
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- HY-W012479S
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H-D-Trp-OH-d5 (D-Tryptophan-d5) is the deuterium labeled H-D-Trp-OH. H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide.
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- HY-10235S
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Telaprevir-d4 is the deuterium labeled Telaprevir. Telaprevir (VX-950) is a highly selective, reversible, and potent peptidomimetic inhibitor of the HCV NS3-4A protease, the steady-state inhibitory constant (Ki) of Telaprevir is 7 nM against a genotype 1 (H strain) NS3 protease domain plus a NS4A cofactor peptide[1][2][3]. Telaprevir inhibits SARS-CoV-2 3CLpro activity[4].
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-
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- HY-14184S
-
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Macitentan-d4 is a deuterium labeled Sulfamethoxazole. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin) receptor antagonist. Macitentan has the potential for idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH)[1].
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-
-
- HY-13631ES4
-
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Deruxtecan-d5 is deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
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-
-
- HY-13631ES
-
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Deruxtecan-d4 is deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
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-
-
- HY-B0282S
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Acetylcholine-d4 (chloride) is the deuterium labeled Acetylcholine chloride. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs)[1][2]. Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro[5].
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-
-
- HY-B0282S1
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Acetylcholine-d9 (chloride) is the deuterium labeled Acetylcholine chloride. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs)[1][2]. Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro[5].
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- HY-B0239S3
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Chloramphenicol-d4 is deuterium labeled Chloramphenicol. Chloramphenicol, a broad-spectrum antibiotic, acts as a potent inhibitor of bacterial protein biosynthesis[1][2]. Chloramphenicol acts primarily on the 50S subunit of bacterial 70S rihosomes and inhibits peptide bond formation by suppressing peptidyl transferase activity[3].
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-
-
- HY-Y1636S1
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Fmoc-Arg(Pbf)-OH- 13C6 is the 13C labeled Fmoc-Arg(Pbf)-OH[1]. Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis)[2].
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-
-
- HY-10119S
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Vorapaxar-d5 is deuterated labeled Vorapaxar (HY-10119). Vorapaxar (SCH 530348), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar (SCH 530348) inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner .
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-
-
- HY-B0290S1
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Pranlukast-d4 is deuterium labeled Pranlukast. Pranlukast is a highly potent, selective and competitive antagonist of peptide leukotrienes. Pranlukast inhibits [3H]LTE4, [3H]LTD4, and [3H]LTC4 bindings to lung membranes with Kis of 0.63±0.11, 0.99±0.19, and 5640±680 nM, respectively.
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-
-
- HY-Y1169S1
-
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Fmoc-Asp(OtBu)-OH- 13C4, 15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[2].
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-
-
- HY-W027544S
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(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d3 is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3].
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-
-
- HY-12366S
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Ubrogepant-d5 (MK-1602-d5) is deuterium labeled Ubrogepant. Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor (CGRP). Ubrogepant has high affinity for CGRP receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by α-CGRP. Ubrogepant can be used in the study of acute migraine .
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-
-
- HY-15306S
-
1 Publications Verification
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Eltrombopag- 13C4 (SB-497115- 13C4) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .
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-
-
- HY-W010712S1
-
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Fmoc-His(Trt)-OH- 15N3 is the 15N labeled Fmoc-His(Trt)-OH[1]. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].
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-
-
- HY-Y1169S2
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Fmoc-Asp(OtBu)-OH-d3 (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate-d3) is deuterium labeled Fmoc-Asp(OtBu)-OH. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis .
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-
-
- HY-W027544S1
-
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(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3]. (7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
-
- HY-13948BS
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Angiotensin II human- 13C6, 15N TFA (Ang II- 13C6, 15N TFA) is 13C- and 15N-labeled Angiotensin II human (TFA) (HY-13948B). Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions .
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-
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- HY-163422S
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PHSHPALTPEQK-(Lys- 13C6, 15N2) is 13C and 15N labeled PHSHPALTPEQK-(Lys).
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-
-
- HY-P1032S
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Angiotensin I- 13C19, 15N3 (human, mouse, rat) is the 13C and 15N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
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-
-
- HY-P4229
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([D8]Val7,10)-C-Peptide (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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-
![([D8]Val7,10)-C-Peptide (human)](//file.medchemexpress.eu/product_pic/hy-p4229.gif)
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- HY-159046S
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ASGITFSNSGMHW(Val-13C5,15N)R TFA is an isotope of ASGITFSNSGMHWVR TFA labeled with 13C and 15N .
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-
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- HY-159065S
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FIQE(Val- 13C5, 15N)NTTTR TFA is the 13C and 15N-labeled FIQE(Val)NTTTR. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-P1142S
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GLP-2(rat) (Ala- 13C3, 15N) is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
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- HY-P2625S
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GLP-2(3-33) (Leu- 13C6, 15N) is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
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- HY-163423S
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TELAEPTSTR-(Arg- 13C6, 15N4) is 13C and 15N labeled TELAEPTSTR-(Arg).
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- HY-P0265AS
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β-Amyloid- 15N (1-40) (TFA) is the 15N-labledβ-Amyloid (1-40) (TFA). β-Amyloid (1-40) is a primary protein in plaques found in the brains of patients with Alzheimer's disease[1].
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- HY-163424S
-
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SSVFVADPK-(Lys- 13C6, 15N2) is 13C and 15N labeled SSVFVADPK-(Lys).
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-
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- HY-P1363S
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β-Amyloid- 15N (1-42), human (TFA) is the 15N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease[1].
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- HY-P2625S1
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GLP-2(3-33) (Leu- 13C6, 15N) TFA is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
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-
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- HY-163426S
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AFFGHYLYEVAR-(Arg- 13C6, 15N4) is 13C and 15N labeled AFFGHYLYEVAR-(Arg) .
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-
-
- HY-P5201S1
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VTSEGAGLQLQK- 13C6, 15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .
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- HY-163425S
-
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AILNYVANK-(Lys- 13C6, 15N2) is 13C and 15N labeled AILNYVANK-(Lys) .
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- HY-159192S
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SADDNIKTPAE(Arg- 13C6, 15N4)LLGPLPPSADDNLKT (TFA) is the 13C and 15N labeled isotope of SADDNIKTPAE-LLGPLPPSADDNLKT (TFA) .
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- HY-159064S
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DSPSAPVNVT(Val- 13C5, 15)R TFA is the 13C and 15N-labeled DSPSAPVNVT(Val)R. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-163992S
-
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VTMTRDTSISTAYMELSR-(Ile-13C6,15N) is the 13C and 15N labeled isotope of VTMTRDTSISTAYMELSR .
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- HY-P1033S1
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[Pyr1]-Apelin-13, Pro( 13C5, 15N) (TFA) is the 13C and 15N labeled isotope of [Pyr1]-Apelin-13(HY-P1033).[Pyr1]-Apelin-13 is a potent and selective endogenous apelin receptor agonist .
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- HY-P1033S
-
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Pyr1]-Apelin-13, Gly(15N) TFA is a Gly 15N labeled [Pyr1]-Apelin-13. [Pyr1]-Apelin-13 is a highly potent, selective endogenous apelin receptor agonist .
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- HY-P1032S2
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Angiotensin I-13C6,15N (human, mouse, rat) TFA is 13C and 15N labeled Angiotensin I (human, mouse, rat) TFA. Angiotensin I-13C6,15N (human, mouse, rat) TFA is a precursor of angiotensin II and is cleaved into angiotensin II by angiotensin converting enzyme (ACE) .
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- HY-163993S
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GMDRWGQGTLVTVSS-(Leu-13C6,15N) is the 13C and 15N labeled isotope of GMDRWGQGTLVTVSS .
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- HY-P0014S2
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Liraglutide- 13C6, 15N (TFA)is the 13C and 15N labeledLiraglutide(HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
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-
- HY-P10324
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TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex .
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- HY-159193S
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DHATS(Leu- 13C6, 15N)PVTIPSAVST(Gly- 13C2, 15N)HTTPLPVTDT (TFA) is the 13C and 15N labeled isotope of DHATS-PVTIPSAVST-HTTPLPVTDT (TFA) .
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- HY-163427S
-
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FNLEALVTHTLPFEK-(Lys- 13C6, 15N2) is 13C and 15N labeled FNLEALVTHTLPFEK-(Lys) .
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-
- HY-P3207S
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DLPLTFGGGT-Lys-13C6,15N2 (TFA) is a deuterated labeled DLPLTFGGGTK .
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- HY-P1142S1
-
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GLP-2(rat) (Ala- 13C3, 15N) TFA is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
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- HY-P0090S
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Calcitonin- 13C6, 15N4 (salmon) (Salmon calcitonin- 13C6, 15N4) TFA is 13C and 15N-labeled Calcitonin (salmon) (HY-P0090). Calcitonin (salmon) , a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption .
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- HY-159191S
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VQPGQN(Phe- 13C9, 15N)HMFTKEKLEEVIKDI (TFA) is the 13C and 15N labeled isotope of VQPGQN-HMFTKEKLEEVIKDI (TFA) .
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| Cat. No. |
Product Name |
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Classification |
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- HY-D1052
-
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Alkynes
Labeling and Fluorescence Imaging
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Cy7-YNE is a fluorescence labeling agent (Ex=700-770 nm，Em=790 nm). Cyanine dyes are used to label proteins, antibodies, and peptides. Cy7-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D0818
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Sulfo-Cyanine3-alkyne
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Alkynes
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CY3-YNE (Sulfo-Cyanine3-alkyne) is a dye for the labeling of soluble proteins, peptides, and oligonucleotides/DNA. CY3-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-D0820
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Sulfo-Cyanine5-alkyne
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Alkynes
|
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CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. CY5-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-151711
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Azide
Labeling and Fluorescence Imaging
|
|
Sulfo-Cy5.5 Azide is a click chemistry reagent containing an azide group. Sulfo-Cy5.5 Azide is also a water-soluble dye (Ex=673 nm, Em=707 nm), which designed to label sensitive molecules such as peptides, proteins and oligonucleotides. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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- HY-147206
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Alkynes
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Biotin-PEG-Alk (MW 600) is a Biotin-labeled Alkyne functionalized polyethylene glycol. Biotin-PEG-Alk (MW 600) can be used to modify proteins, peptides, and oligonucleotides . Biotin-PEG-Alk (MW 600) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-112295
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|
Azide
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AzKTB is a capture reagent which bears a short trypsin-cleavable peptide sequence between the azide module and the TAMRA/PEG-biotin labels. AzKTB is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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-
- HY-W027544S1
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|
5-(Dimethyl-d6-amino)-N-(prop-2-ynyl)naphthalene-1-sulfonamide
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Alkynes
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(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3]. (7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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