Search Result

Results for "

penetrating

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (5) Amino Acid Derivatives (4) Aminopeptidase (2) Amyloid-β (3) Antibiotic (6) Antibody-Drug Conjugates (ADCs) (1) Apoptosis (9) Aryl Hydrocarbon Receptor (1) Atg8/LC3 (1) ATM/ATR (1) Autophagy (3) Bacterial (15) Beclin1 (1) Beta-secretase (3) Btk (1) Calcium Channel (3) CaMK (1) Caspase (1) Cathepsin (2) Cholinesterase (ChE) (1) Complement System (1) COX (1) CXCR (3) Deubiquitinase (1) Endogenous Metabolite (4) Epigenetic Reader Domain (2) ERK (5) FABP (1) Fluorescent Dye (6) Glucosidase (1) GnRH Receptor (1) Guanylate Cyclase (1) HDAC (1) Histamine Receptor (7) HIV (17) IFNAR (1) iGluR (6) Influenza Virus (1) Insulin Receptor (2) Integrin (8) Interleukin Related (2) JNK (3) LRRK2 (1) MDM-2/p53 (1) MEK (1) Melanocortin Receptor (2) Mitophagy (1) MMP (1) Monoamine Oxidase (4) MyD88 (1) Na+/K+ ATPase (1) nAChR (1) Neuropeptide Y Receptor (2) NF-κB (4) NO Synthase (2) Nuclear Factor of activated T Cells (NFAT) (3) Opioid Receptor (2) Orexin Receptor (OX Receptor) (1) Oxytocin Receptor (2) Phosphatase (1) Phosphodiesterase (PDE) (1) PI3K (2) Pim (1) PKC (5) Potassium Channel (2) Prolyl Endopeptidase (PREP) (1) Protease Activated Receptor (PAR) (5) Proteasome (1) RABV (3) Reactive Oxygen Species (1) RIP kinase (1) Sodium Channel (2) Somatostatin Receptor (1) Src (2) Transferrin Receptor (3) TRP Channel (4) VEGFR (1) α-synuclein (2) γ-secretase (1)
By Research Areas:	Cancer (75) Cardiovascular Disease (18) Endocrinology (9) Infection (33) Inflammation/Immunology (35) Metabolic Disease (16) Neurological Disease (50)

By Targets:

Adrenergic Receptor (5)

Amino Acid Derivatives (4)

Aminopeptidase (2)

Amyloid-β (3)

Antibiotic (6)

Antibody-Drug Conjugates (ADCs) (1)

Apoptosis (9)

Aryl Hydrocarbon Receptor (1)

Atg8/LC3 (1)

ATM/ATR (1)

Autophagy (3)

Bacterial (15)

Beclin1 (1)

Beta-secretase (3)

Btk (1)

Calcium Channel (3)

CaMK (1)

Caspase (1)

Cathepsin (2)

Cholinesterase (ChE) (1)

Complement System (1)

COX (1)

CXCR (3)

Deubiquitinase (1)

Endogenous Metabolite (4)

Epigenetic Reader Domain (2)

ERK (5)

FABP (1)

Fluorescent Dye (6)

Glucosidase (1)

GnRH Receptor (1)

Guanylate Cyclase (1)

HDAC (1)

Histamine Receptor (7)

HIV (17)

IFNAR (1)

iGluR (6)

Influenza Virus (1)

Insulin Receptor (2)

Integrin (8)

Interleukin Related (2)

JNK (3)

LRRK2 (1)

MDM-2/p53 (1)

MEK (1)

Melanocortin Receptor (2)

Mitophagy (1)

MMP (1)

Monoamine Oxidase (4)

MyD88 (1)

Na+/K+ ATPase (1)

nAChR (1)

Neuropeptide Y Receptor (2)

NF-κB (4)

NO Synthase (2)

Nuclear Factor of activated T Cells (NFAT) (3)

Opioid Receptor (2)

Orexin Receptor (OX Receptor) (1)

Oxytocin Receptor (2)

Phosphatase (1)

Phosphodiesterase (PDE) (1)

PI3K (2)

Pim (1)

PKC (5)

Potassium Channel (2)

Prolyl Endopeptidase (PREP) (1)

Protease Activated Receptor (PAR) (5)

Proteasome (1)

RABV (3)

Reactive Oxygen Species (1)

RIP kinase (1)

Sodium Channel (2)

Somatostatin Receptor (1)

Src (2)

Transferrin Receptor (3)

TRP Channel (4)

VEGFR (1)

α-synuclein (2)

γ-secretase (1)

By Research Areas:

Cancer (75)

Cardiovascular Disease (18)

Endocrinology (9)

Infection (33)

Inflammation/Immunology (35)

Metabolic Disease (16)

Neurological Disease (50)

175

Inhibitors & Agonists

Biochemical Assay Reagents

208

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Low molecular weight protamine LMWP	VEGFR	Cancer
Low molecular weight protamine is a cell-penetrating peptide with vascular endothelial growth factor (VEGF) inhibitory activity. Low molecular weight protamine can inhibit tumor growth and is used in cancer research .

Cys-Penetratin	Amino Acid Derivatives	Others
Cys-Penetratin is a cell-penetrating peptide (CPP) with sequence of CRQIKIWFQNRRMKWKK .

ML418	Potassium Channel	Cardiovascular Disease Neurological Disease Endocrinology
ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker. ML418 inhibits Kir7.1 with an IC₅₀ value of 0.31 μM. ML418 can be used for the research of neurological, cardiovascular, endocrine and muscle disorders.

K 01-162 K162	Amyloid-β	Neurological Disease
K 01-162 (K162) inhibits the fibril formation of Aβ peptides and eliminates their neurotoxicity. K 01-162 binds with Aβ₄₂ peptide with an EC₅₀ value of 80 nM. K 01-162 binds directly to AβO with a KD value of 19 μM. K 01-162 is capable of penetrating the brain and can be used for the research of Alzheimer’s disease .

Enadoline CI-977	Opioid Receptor	Neurological Disease
Enadoline (CI-977) is a highly selective, brain-penetrating, and nonpeptide kappa-opioid receptor (KOR) agonist (K_i=1.25 nM). Antinociceptive effects .

Enadoline hydrochloride CI-977 hydrochloride	Opioid Receptor	Neurological Disease
Enadoline (CI-977) hydrochloride is a highly selective, brain-penetrating, and nonpeptide kappa-opioid receptor (KOR) agonist (K_i=1.25 nM). Antinociceptive effects .

CPP9	Fluorescent Dye	Cancer
CPP9 is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP9 can be used for intracellular delivery of therapeutic agents and chemical probes .

CPP12	Fluorescent Dye	Cancer
CPP12 is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP12 can be used for intracellular delivery of therapeutic agents and chemical probes .

TAT (47-57), TAMRA-labeled	Amino Acid Derivatives	Others
TAT (47-57), TAMRA-labeled is a TAMRA-labeled peptide with cell-penetrating activity.

Parstatin(mouse)	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(mouse), a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

Parstatin(human)	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(human), a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

Cys(Npys)-TAT (47-57), FAM-labeled	Amino Acid Derivatives	Others
Cys(Npys)-TAT (47-57), FAM-labeled is a Cys(Npys)-activated cell-penetrating peptide with FAM-labeled .

Parstatin(human) TFA	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(human) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

Parstatin(mouse) TFA	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(mouse) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

TAT peptide	HIV	Infection
TAT peptide is a cell penetrating peptide (GRKKRRQRRRPQ) derived from the trans-activating transcriptional activator (Tat) from HIV-1 .

TAT peptide TFA	HIV	Infection
TAT peptide (TFA) is a cell penetrating peptide (GRKKRRQRRRPQ) derived from the trans-activating transcriptional activator (Tat) from HIV-1 .

TAT (47-57), FAM-labeled	HIV	Others
TAT (47-57), FAM-labeled is a cell-penetrating peptide (CPP). TAT (47-57), FAM-labeled has the potential for intracellular drug delivery research .

Cys-TAT(47-57) Cys-[HIV-Tat (47-57)]	HIV	Infection
Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) is an arginine rich cell penetrating peptide derived from the HIV-1 transactivating protein.

FITC-LC-TAT (47-57)	HIV	Others
FITC-LC-TAT (47-57) is a FITC labeled TAT peptide. TAT is a cell-penetrating peptide (CPP). TAT can increase the yields and the solubility of heterologous proteins .

Cys-TAT(47-57) TFA Cys-[HIV-Tat (47-57)] TFA	HIV	Infection
Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) is an arginine rich cell penetrating peptide derived from the HIV-1 transactivating protein.

Rabies Virus Glycoprotein 1 Publications Verification	RABV	Infection
Rabies Virus Glycoprotein is a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein that can cross the blood-brain barrier (BBB) and enter brain cells.

TAT (47-57) GGG-Cys(Npys)	HIV	Others
TAT (47-57) GGG-Cys(Npys) is a cell-penetrating peptide (CPP). TAT (47-57) GGG-Cys(Npys) has the potential for intracellular drug delivery research .

Rabies Virus Glycoprotein TFA 1 Publications Verification	RABV	Infection
Rabies Virus Glycoprotein (TFA) is a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein that can cross the blood-brain barrier (BBB) and enter brain cells .

TAT TFA	HIV	Infection
TAT TFA (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins .

TAT	HIV	Infection
TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins .

iRGD peptide 5 Publications Verification c(CRGDKGPDC)	Integrin	Cancer
iRGD peptide is a 9-amino acid cyclic peptide, triggers tissue penetration of agents by first binding to αv-integrins, then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties.

HIV-1 TAT (48-60)	HIV	Infection
HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way.

TAT-HA2 Fusion Peptide	Influenza Virus	Infection
TAT-HA2 Fusion Peptide is a peptide-based delivery agent that combines the pH-sensitive HA2 fusion peptide from Influenza and the cell-penetrating peptide TAT from HIV. TAT-HA2 Fusion Peptide is a transactivator of transcription and hemaglutanin for endosomal release. TAT-HA2 Fusion Peptide enhances cellular uptake of macromolecules .

mPEG-PLGA	Others	Others
mPEG-PLGA is a mucus-penetrating polymer. mPEG-PLGA is a raw material to prepare nanomedicine .

TAT-DEF-Elk-1 2 Publications Verification TDE	ERK	Neurological Disease
TAT-DEF-Elk-1 (TDE) is a cell-penetrating peptide inhibitor of?Elk-1,?mimics and specifically interferes with the DEF domain of Elk-1. TAT-DEF-Elk-1 blocks Elk-1 phosphorylation and prevents Elk-1 nuclear translocation without interfering with ERK nor MSK1 activation. TAT-DEF-Elk-1 is a useful tool to analyze the role of Elk-1 in this process during the development of neuronal plasticity .

Visomitin 15+ Cited Publications SKQ1	Reactive Oxygen Species	Inflammation/Immunology
Visomitin (SKQ1) is a mitochondrial-targeted antioxidant with the high mitochondrion membrane penetrating ability and potent antioxidant capability .

TAT-DEF-Elk-1 TFA TDE TFA	ERK	Neurological Disease
TAT-DEF-Elk-1 TFA (TDE TFA) is a cell-penetrating peptide inhibitor of?Elk-1,?mimics and specifically interferes with the DEF domain of Elk-1. TAT-DEF-Elk-1 TFA blocks Elk-1 phosphorylation and prevents Elk-1 nuclear translocation without interfering with ERK nor MSK1 activation. TAT-DEF-Elk-1 TFA is a useful tool to analyze the role of Elk-1 in this process during the development of neuronal plasticity .

TAT-PiET	Epigenetic Reader Domain	Cancer
TAT-PiET is a cell-penetrating peptide targeting the extra-terminal (ET) domain of BRD4 that disrupts the BRD4/JMJD6 interaction. BRD4/JMJD6 is a protein complex that is critical for oncogene expression and breast cancer, and TAT-PiET inhibits BRD4/JMJD6 target gene expression and breast cancer cell growth. TAT-PiET also resists endocrine resistance in ERα-positive breast cancer cells and is a potential inhibitor of breast cancer .

Coumarinic acid	Amyloid-β Cholinesterase (ChE)	Neurological Disease
Coumarinic acid is a brain-penetrating inhibitor of AChE and β-amyloid. Coumarinic acid can be used in study anti-Alzheimer drug .

A-304121	Histamine Receptor	Neurological Disease
A-304121 is a selective and brain penetrating H3 receptor antagonist. A-304121 is a cognition-enhancing agent .

Calpeptin 20+ Cited Publications	Cathepsin Proteasome Apoptosis	Inflammation/Immunology
Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID₅₀ of 40 nM for Calpain I in human platelets . Calpeptin is also an inhibitor of cathepsin K .

Lanabecestat AZD3293; LY3314814	Beta-secretase	Neurological Disease
Lanabecestat (AZD3293) is a potent, orally active and blood-brain barrier penetrating BACE1 inhibitor with a K_i of 0.4 nM. Lanabecestat is used for the research of Alzheimer's disease .

AZ32	ATM/ATR	Cancer
AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC₅₀ of <6.2 nM for ATM enzyme, and an IC₅₀ of 0.31 μM for ATM in cell.

PF-06478939	Oxytocin Receptor	Cardiovascular Disease
PF-06478939 is a non-brain-penetrating peptide that is an agonist at oxytocin (OT) receptor and vasopressin receptor with EC₅₀ values of 0.01 nM and 0.078 nM, respectively .

Lanabecestat camsylate LY3314814 camsylate; AZD3293 camsylate	Beta-secretase	Neurological Disease
Lanabecestat camsylate is a potent, orally active and blood-brain barrier penetrating BACE1 inhibitor with a K_i of 0.4 nM. Lanabecestat camsylate is used for the research of Alzheimer's disease .

RIP1 kinase inhibitor 1	RIP kinase	Inflammation/Immunology
RIP1 kinase inhibitor 1 (compound 22) is a highly potent, orally available, and brain-penetrating RIP1 kinase inhibitor (pK_i=9.04) .

PF-06478939 TFA	Oxytocin Receptor	Cardiovascular Disease
PF-06478939 TFA is a non-brain-penetrating peptide that is an agonist at oxytocin (OT) receptor and vasopressin receptor with EC₅₀ values of 0.01 nM and 0.078 nM, respectively .

DNS-8254	Phosphodiesterase (PDE)	Neurological Disease
DNS-8254 is an oral active and brain-penetrating PDE2a inhibitor with the IC₅₀ of 8 nM. DNS-8254 shows memory enhancing effects in a rat model .

Apinocaltamide ACT-709478	Calcium Channel	Neurological Disease
Apinocaltamide (ACT-709478) is a potent, selective, orally active, and brain penetrating T-type calcium channel blocker. ACT-709478 is used in the research of generalized epilepsies .

(Rac)-Minzasolmin (Rac)-UCB0599; NPT200-11	α-synuclein	Neurological Disease
(Rac)-Minzasolmin ((Rac)-UCB0599) is a brain penetrating inhibitor of accumulation of alpha-synuclein (ASYN) misfolding and aggregation. (Rac)-Minzasolmin can be used for research of Parkinson's disease .

KYP-2047	Apoptosis MDM-2/p53 Prolyl Endopeptidase (PREP)	Cancer
KYP-2047 is a potent and BBB-penetrating prolyl-oligopeptidase (POP) inhibitor, with an K_i value of 0.023 nM. KYP-2047 reduces glioblastoma proliferation through angiogenesis and apoptosis modulation .

Cat. No.	Product Name	Type

HY-W039923

β-D-Galactose pentaacetate	Carbohydrates
β-D-Galactose pentaacetate is a negative regulator of insulin with plasma membrane penetrating ability and can be hydrolyzed by intracellular esterases. β-D-Galactose pentaacetate inhibits leucine-induced insulin release in Wistar rat islets, potentially preventing excessive insulin release in pathological conditions .

Cat. No.	Product Name	Target	Research Area

HY-P2193

TAT-amide	Peptides	Infection
TAT-amide is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells .

HY-P0123

SPACE peptide 3 Publications Verification	Peptides	Others
SPACE peptide is a skin penetrating peptide (SPPs). SPACE peptide can enhance topical delivery of a macromolecule, hyaluronic acid .

HY-P4084A

KLA seq acetate	Peptides	Others
KLA seq acetate is a cell membrane-penetrating α-helical amphipathic model peptide. KLA seq acetate conjugates peptide nucleic acids (PNAs) for delivery to mammalian cells. KLA seq acetate covalently links targeted mRNA and fluorescein to form a delivery system that has low re-export and is less resistant to serum effects .

HY-P4118

EB1 peptide penetrating analog	Peptides	Others
EB1 peptide (Penetrating analog), a Penetratin peptide derivative, is an amphipathic cell-penetrating peptide (CPP). EB1 peptide has the potential for intracellular drug delivery research .

HY-P10156

MAP17 Cell-penetrating peptide MAP17	Peptides	Others
MAP17 (Cell-penetrating peptide MAP17) is a synthetic secondary amphipathic cell-penetrating peptides, with sequence of QLALQLALQALQAALQLA .

HY-P4139

*activable cell-penetrating* peptide (ACCP)**	Peptides	Others
activable cell-penetrating peptide (ACCP) consists of a polycationic CPP (typically arg9 or r9) connected via a cleavable linker to a matching polyanion (typically glu9 or e9), which reduces the net charge to nearly zero and thereby inhibits adhesion and uptake into cells .

HY-P2193A

TAT-amide TFA	Peptides	Infection
TAT-amide TFA is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells .

HY-P4087

Cys(Npys)-(Arg)9	Peptides	Others
Cys(Npys)-(Arg)9 is a cell penetrating peptide. Cys(Npys)-(Arg)9 is comprised of 9 D-Arginine residues and an activated cysteine residue C(Npys). Cys(Npys)-(Arg)9 can be used as a carrier peptide applicable in conjugation and cell permable studies .

HY-P10733

LAH4-L1	Peptides	Others
LAH4-L1 Is a histidine-rich cell penetrating peptide. LAH4-L1 can form complexes with DNA or siRNA and help their transport .

HY-P10644

CPP9	Fluorescent Dye	Cancer
CPP9 is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP9 can be used for intracellular delivery of therapeutic agents and chemical probes .

HY-P10649

CPP12	Fluorescent Dye	Cancer
CPP12 is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP12 can be used for intracellular delivery of therapeutic agents and chemical probes .

HY-P10644A

CPP9 TFA	Peptides	Cancer
CPP9 TFA is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP9 TFA can be used for intracellular delivery of therapeutic agents and chemical probes .

HY-P5107

Low molecular weight protamine LMWP	VEGFR	Cancer
Low molecular weight protamine is a cell-penetrating peptide with vascular endothelial growth factor (VEGF) inhibitory activity. Low molecular weight protamine can inhibit tumor growth and is used in cancer research .

HY-P1848

Pep-1 (uncapped)	Peptides	Cancer
Pep-1 (uncapped) is a cell-penetrating peptide.

HY-P4093

Cys-Penetratin	Amino Acid Derivatives	Others
Cys-Penetratin is a cell-penetrating peptide (CPP) with sequence of CRQIKIWFQNRRMKWKK .

HY-P4077

Antennapedia Peptide, amide Penetratin amide	Peptides	Others
Antennapedia Peptide, amide is a C-terminal amide cell-penetrating peptide .

HY-P4090

CPP2	Peptides	Others
CPP2 is a cell-penetrating peptide, with a high intracellular translocation efficiency .

HY-P4084

KLA seq	Peptides	Others
KLA seq is a cell-penetrating α-helical amphipathic model peptide .

HY-P4105

TAT (47-57), TAMRA-labeled	Amino Acid Derivatives	Others
TAT (47-57), TAMRA-labeled is a TAMRA-labeled peptide with cell-penetrating activity.

HY-P4134

Lipid Membrane Translocating Peptide	Peptides	Others
Lipid Membrane Translocating Peptide is a cell-penetrating peptide consisting of 13 amino acids .

HY-P4075

Antennapedia Leader Peptide (CT)	Peptides	Others
Antennapedia Leader Peptide (CT) is a cell penetrating peptide that can be used for drug delivery .

HY-P4131

MPS-Gαi3	Peptides	Others
MPS-Gαi3 is a cell penetrating peptide that can be used for drug delivery .

HY-P1261

Parstatin(mouse)	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(mouse), a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

HY-P1262

Parstatin(human)	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(human), a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

HY-P4103

Cys(Npys)-TAT (47-57), FAM-labeled	Amino Acid Derivatives	Others
Cys(Npys)-TAT (47-57), FAM-labeled is a Cys(Npys)-activated cell-penetrating peptide with FAM-labeled .

HY-P10190

CADY	Peptides	Others
CADY is a *cell-penetrating* peptide (CPPs)** peptide with a sequence of GLWRALWRLLRSLWRLLWRA. CADY can be used as a vector tool for intracellular delivery .

HY-P1262A

Parstatin(human) TFA	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(human) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

HY-P1261A

Parstatin(mouse) TFA	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
Parstatin(mouse) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis .

HY-P4081

plsl	Peptides	Others
Plsl is a cell-penetrating peptide (CPP), with sequence of RVIRVWFQNKRCKDKK. Plsl, belongs to Penetralia family, and origins from Igl-1 homeodomain .

HY-P0282

TAT peptide	HIV	Infection
TAT peptide is a cell penetrating peptide (GRKKRRQRRRPQ) derived from the trans-activating transcriptional activator (Tat) from HIV-1 .

HY-P4132

Membrane-Permeable Sequence, MPS	Peptides	Cancer
Membrane-Permeable Sequence, MPS is a cell-penetrating peptide (CPP). Membrane-Permeable Sequence, MPS can be used for the research of membrane crossing mechanism .

HY-P0282A

TAT peptide TFA	HIV	Infection
TAT peptide (TFA) is a cell penetrating peptide (GRKKRRQRRRPQ) derived from the trans-activating transcriptional activator (Tat) from HIV-1 .

HY-P4098

SynB1	Peptides	Others
SynB1 is a cell penetrating polypeptide, internalized by, or is associated with lipid vesicle (LV). SynB1 can be used to lipid vesicle-mediated delivery to cells .

HY-P4122

TAT (47-57), FAM-labeled	HIV	Others
TAT (47-57), FAM-labeled is a cell-penetrating peptide (CPP). TAT (47-57), FAM-labeled has the potential for intracellular drug delivery research .

HY-P1801

Cys-TAT(47-57) Cys-[HIV-Tat (47-57)]	HIV	Infection
Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) is an arginine rich cell penetrating peptide derived from the HIV-1 transactivating protein.

HY-P4125

FITC-LC-TAT (47-57)	HIV	Others
FITC-LC-TAT (47-57) is a FITC labeled TAT peptide. TAT is a cell-penetrating peptide (CPP). TAT can increase the yields and the solubility of heterologous proteins .

HY-P1801A

Cys-TAT(47-57) TFA Cys-[HIV-Tat (47-57)] TFA	HIV	Infection
Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]) is an arginine rich cell penetrating peptide derived from the HIV-1 transactivating protein.

HY-P0307

Antennapedia Peptide Penetratin peptide	Peptides	Cancer
Antennapedia Peptide (Penetratin peptide) is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of cell-penetrating peptides.

HY-P0285

Rabies Virus Glycoprotein 1 Publications Verification	RABV	Infection
Rabies Virus Glycoprotein is a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein that can cross the blood-brain barrier (BBB) and enter brain cells.

HY-P4123

TAT (47-57) GGG-Cys(Npys)	HIV	Others
TAT (47-57) GGG-Cys(Npys) is a cell-penetrating peptide (CPP). TAT (47-57) GGG-Cys(Npys) has the potential for intracellular drug delivery research .

HY-P10443

ppTG20	Peptides	Others
ppTG20 is an amphiphilic cell penetrating peptide (KALA) that can be used for gene transfection. ppTG20 can bind to DNA, destabilize membranes, and mediate DNA transfection .

HY-P0307A

Antennapedia Peptide TFA Penetratin peptide TFA	Peptides	Inflammation/Immunology Cancer
Antennapedia Peptide (Penetratin peptide) TFA is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of cell-penetrating peptides.

HY-P0285A

Rabies Virus Glycoprotein TFA 1 Publications Verification	RABV	Infection
Rabies Virus Glycoprotein (TFA) is a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein that can cross the blood-brain barrier (BBB) and enter brain cells .

HY-P0281A

TAT TFA	HIV	Infection
TAT TFA (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins .

HY-P0281

TAT	HIV	Infection
TAT (YGRKKRRQRRR) is derived from the transactivator of transcription (TAT) of human immunodeficiency virus-1 (HIV-1) and is a cell-penetrating peptide. TAT can increase the yields and the solubility of heterologous proteins .

HY-P0122B

iRGD peptide 1 TFA	Peptides	Cancer
iRGD peptide 1 TFA is the prototypic tumor-specific tissue-penetrating peptide, which delivers agents deep into extravascular tumor tissue. iRGD peptide 1 TFA has anti-metastatic activity .

HY-P2500

(Arg)9, FAM-labeled	Peptides	Others
(Arg)9, FAM-labeled, a cell-penetrating peptide (CPP), is a nona-arginine (ARG) with FAM label. CPPs have emerged as powerful tools for delivering bioactive cargoes into the cytosol of intact cells .

HY-P3432

DfTat	Peptides	Others
DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .

HY-P1732

Transportan	Peptides	Cancer
Transportan is a 27 amino acid-long peptide containing 12 functional amino acids from the amino terminus of the neuropeptide galanin and mastoparan in the carboxyl terminus, connected via a lysine. Transportan belongs to cell-penetrating peptides (CPPs) .

HY-P1781

Peptide C105Y	Peptides	Cancer
Peptide C105Y, a synthetic and cell-penetrating peptide based on the amino acid sequence corresponding to residues 359-374 of α1-antitrypsin, enhances gene expression from DNA nanoparticles .

Cat. No.	Product Name	Target	Research Area

HY-P99530

Valanafusp alfa AGT-181; HIRMAb-IDUA	Insulin Receptor	Metabolic Disease
Valanafusp alfa (AGT-181) is a chimeric monoclonal antibody that fuses human α-L-iduronidase (IDUA) and targets the human insulin receptor (HIR). Valanafusp alfa has brain penetrating properties, making it useful for research on mucopolysaccharidosis type I (MPS I) .

HY-P99803

Clervonafusp alfa VAL-1221	Glucosidase	Others
Clervonafusp alfa (VAL-1221) is a fusion protein targeting both cytosolic and lysosomal glycogen. Clervonafusp alfa is comprised of the Fab portion of a cell-penetrating antibody and recombinant human acid alpha glucosidase (rhGAA), the former utilizing the nucleoside transporter ENT-2 to gain access to the cytosol, and the latter enters lysosomes via mannose-6-phosphate receptors (M6PRs). Clervonafusp alfa can be used for late-onset Pompe disease research .

Cat. No.	Product Name	Chemical Structure

HY-B1075AS

(Rac)-Fosfomycin (benzylamine)-13C3

(Rac)-Fosfomycin (benzylamine)- ¹³C₃ is the ¹³C labeled Fosfomycin[1]. Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[2][3].

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