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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

mast cell

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Adenosine Receptor (1) Akt (2) Anaplastic lymphoma kinase (ALK) (1) Antibiotic (4) Apoptosis (3) Aurora Kinase (2) Bacterial (3) Bcr-Abl (2) Biochemical Assay Reagents (1) Btk (1) c-Kit (4) Cathepsin (1) Cholinesterase (ChE) (1) Complement System (1) CRAC Channel (1) Endogenous Metabolite (8) FLT3 (2) Fluorescent Dye (3) Fungal (1) GPR35 (1) Histamine Receptor (27) Influenza Virus (7) Interleukin Related (5) Isotope-Labeled Compounds (3) Leukotriene Receptor (3) Lipoxygenase (1) LPL Receptor (2) Mas-related G-protein-coupled Receptor (MRGPR) (3) Monoamine Oxidase (1) NF-κB (2) p38 MAPK (3) Parasite (1) PDGFR (3) Phosphatase (3) Phosphodiesterase (PDE) (1) Phospholipase (2) Prostaglandin Receptor (5) Protease Activated Receptor (PAR) (1) Proteasome (1) SARS-CoV (4) Ser/Thr Protease (2) SHP2 (1) STAT (3) Syk (3) TNF Receptor (5) VEGFR (3) Virus Protease (1)
By Research Areas:	Cancer (19) Cardiovascular Disease (5) Endocrinology (22) Infection (14) Inflammation/Immunology (82) Metabolic Disease (1) Neurological Disease (7)
Oligonucleotides:	Solvents (1)

118

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: Itk TOPK NAMPT ALCAM/CD166 GDNF Receptor BCL6 Tim3 BMI1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-115768A

Compound 48/80 (trimer) Poly-p-methoxyphenethylmethylamine (trimer)	Others	Others
Compound 48/80 (trimer) is a trimer of Compound 48/80 (HY-115768). Compound 48/80 is widely used in animal and tissue models as a "selective" mast cell activator .

HY-115768

Compound 48/80 Poly-p-methoxyphenethylmethylamine	Others	Neurological Disease Cancer
Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" **mast cell** activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways .

HY-B0640A

Epinastine hydrochloride WAL801 hydrochloride	Histamine Receptor	Inflammation/Immunology Endocrinology
Epinastine hydrochloride (WAL801 hydrochloride) is an antihistamine and mast cell stabilizer. Epinastine hydrochloride is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine hydrochloride also inhibits IL-8 release and has an antiallergic action .

HY-B0640

Epinastine WAL801	Histamine Receptor	Inflammation/Immunology Endocrinology
Epinastine (WAL801) is an antihistamine and mast cell stabilizer. Epinastine is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine also inhibits IL-8 release and has an antiallergic action .

HY-P1807

Mast Cell Degranulating Peptide HR-2	Histamine Receptor	Inflammation/Immunology
Mast Cell Degranulating Peptide HR-2, a 14-membered linear peptide isolated from the venom of the giant hornet Vespa orientalis, is capable of degranulating mast cells and thus initiating histamine release .

HY-145892

MrgprX2 antagonist-6	Mas-related G-protein-coupled Receptor (MRGPR)	Inflammation/Immunology
MrgprX2 antagonist-6 (compound 9) is an anti-allergic agent. MrgprX2 antagonist-6 shows excellent anti-allergy effects and can inhibit mast cell degranulation .

HY-145893

MrgprX2 antagonist-7	Mas-related G-protein-coupled Receptor (MRGPR)	Inflammation/Immunology
MrgprX2 antagonist-7 (compound 10) is an anti-allergic agent. MrgprX2 antagonist-7 shows excellent anti-allergy effects and can inhibit mast cell degranulation .

HY-W062109

Olopatadine	Endogenous Metabolite Histamine Receptor	Inflammation/Immunology
Olopatadine is an orally active and selective histamine 1 (H₁) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic conjunctivitis .

HY-105999A

APC 366 hydrochloride	Ser/Thr Protease	Inflammation/Immunology
APC 366 hydrochloride is a selective inhibitor of mast cell trypsin activity. APC 366 hydrochloride is able to inhibit trypsin-induced histamine release in human tonsil and lung cells. APC 366 hydrochloride may have important applications in regulating allergic reactions and inflammation .

HY-122295

Dehydroleucodine	Apoptosis	Inflammation/Immunology Cancer
Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana. Dehydroleucodine is a mast cell stabilizer that inhibits tmast cell degranulation induced by compound 48/80. Dehydroleucodine inudces cells apoptosis, and has gastric ulcer inhibition and antileukemic effects .

HY-105999

APC 366	Ser/Thr Protease	Inflammation/Immunology
APC 366 is a selective inhibitor of mast cell tryptase (K_i=7.1 μM). APC 366 inhibits antigen-induced early asthmatic response (EAR), late asthmatic response (LAR), and bronchial hyperresponsiveness (BHR) in a sheep model of allergic asthma .

HY-12521

GSK-5498A 3 Publications Verification	CRAC Channel	Inflammation/Immunology
GSK-5498A is a selective CARC channel inhibitor (IC₅₀: 1 μM). GSK-5498A inhibits mediators release from mast cells and pro-inflammatory cytokines release from T cells. GSK-5498A can be used in the research of inflammatory disorders .

HY-N7885

(25R)-Spirost-4-ene-3,12-dione (-)-(25R)-Spirost-4-ene-3,12-dione	Others	Inflammation/Immunology
(25R)-Spirost-4-ene-3,12-dione ((-)-(25R)-Spirost-4-ene-3,12-dione) is a natural product that has an inhibitory effect on neutrophil superoxide anion production and histamine release from mast cells .

HY-131162

Chymase	Others	Cardiovascular Disease
Chymase is a protein-digester enzyme found primarily in mast cells (MC), fibroblasts, and vascular endothelial cells. Chymase is released into the extracellular stroma in the context of inflammatory signals, tissue injury and cellular stress. Chymase is also involved in angiotensin II (Ang II) production, which is used in cardiovascular disease studies .

HY-126127

BRL 22321 free base	Others	Inflammation/Immunology
BRL 22321 free base is a stabilizer with similar mast cell stabilizing activity to Cromolyn sodium (HY-B0320A) and also has some smooth muscle relaxant activity. BRL 22321 free base is more potent than Cromolyn sodium (HY-B0320A) in inhibiting rat passive cutaneous and peritoneal anaphylaxis and antigen-induced histamine release from passively sensitized rat peritoneal cells .

HY-13508

JNJ-7777120 1 Publications Verification	Histamine Receptor	Inflammation/Immunology
JNJ-7777120 is a potent and selective histamine H₄ receptor antagonist (K_i=4.5 nM). JNJ-7777120 effectively blocks histamine-induced migration of mouse tracheal mast cells from connective tissue to epithelial cells. JNJ-7777120 also significantly blocks neutrophil infiltration in a mouse Zymosan-induced peritonitis model. JNJ-7777120 has a good potential to study antipruritic and anti-inflammatory .

HY-P99193

Enokizumab MEDI-528	Interleukin Related	Inflammation/Immunology
Enokizumab (MEDI-528) is a monoclonal antibody targeting to interleukin (IL)-9. IL-9 regulates the development of airway inflammation, mucus production, airway hyperresponsiveness, and airway fibrosis largely by increasing mast cell numbers and activity in the airways .

HY-138961

ER-27319	Syk	Inflammation/Immunology
ER-27319, an acridone derivative, is a potent and selective SYK inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC₅₀ of 10 μM and can be used for study in allergic diseases .

HY-108489

ER-27319 maleate	Syk	Inflammation/Immunology
ER-27319 (maleate), an acridone derivative, is a potent and selective SKY inhibitor, and inhibits the tyrosine phosphorylation of SYK and its activity. ER-27319 (maleate) inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC₅₀ of 10 μM and can be used for study in allergic diseases ^[1] ^[2].

HY-D1425

DCVJ 9-(2,2-Dicyanovinyl)julolidine	Fluorescent Dye	Others
DCVJ (9-(2,2-Dicyanovinyl)julolidine), a molecular rotor and unique fluorescent dye, binds to tubulin and actin, and increases its fluorescence intensity drastically upon polymerization. DCVJ also binds to phospholipid bilayers and increases its fluorescence intensity. DCVJ can detect the kinetic process of degranulation of mast cells .

HY-P99371

Lirentelimab AK002; Anti-Siglec-8 Reference Antibody (lirentelimab)	Apoptosis	Inflammation/Immunology
Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis .

HY-B0157A

Ketotifen fumarate 3 Publications Verification HC 20511 fumarate	Histamine Receptor Endogenous Metabolite SARS-CoV Influenza Virus	Inflammation/Immunology Endocrinology Cancer
Ketotifen (HC 20-511) fumarate is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen fumarate can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen fumarate also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen fumarate can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention .

HY-B0157

Ketotifen 3 Publications Verification HC 20-511	Endogenous Metabolite Histamine Receptor SARS-CoV Influenza Virus	Infection Inflammation/Immunology Endocrinology
Ketotifen (HC 20-511) is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention .

HY-N3007A

(E)-Naringenin chalcone	Others	Inflammation/Immunology
(E)-Naringenin chalcone is an orally active anti-allergic agent. (E)-Naringenin chalcone also has antioxidant, anti-inflammatory activities. (E)-Naringenin chalcone can improve adipocyte functions. (E)-Naringenin chalcone inhibits histamine release from rat peritoneal mast cell .

HY-D0220A

Toluidine Blue (purity 36%) Toluidine Blue O (purity 36%)	Fluorescent Dye	Others Cancer
Toluidine Blue (Toluidine Blue O) purity 36% is an alkaline quinonimine dye (vivo dye) with high affinity for acidic tissue components, staining nuclei blue and polysaccharides purple. Toluidine Blue purity 36% shows heterostaining properties for mast cells, mucins and chondrocytes. Toluidine Blue purity 36% can stain different components of plant tissues and cells in different colours. Toluidine Blue purity 36% is also used as a diagnostic aid to identify malignant lesions, such as cancer .

HY-B0157AR

Ketotifen fumarate (Standard)	Histamine Receptor Endogenous Metabolite SARS-CoV Influenza Virus	Inflammation/Immunology Endocrinology Cancer
Ketotifen (fumarate) (Standard) is the analytical standard of Ketotifen (fumarate). This product is intended for research and analytical applications. Ketotifen (HC 20-511) fumarate is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen fumarate can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen fumarate also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen fumarate can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention .

HY-123532

JNJ10191584 VUF6002	Histamine Receptor	Neurological Disease
JNJ10191584 (VUF6002) is an orally active and selective histamine H₄ receptor antagonist with a K_i value of 26 nM. JNJ10191584 shows 540-fold selectivity to H₄ receptor over H₃ receptor with a K_i value of 14.1 μM. JNJ10191584 inhibits chemotaxis of eosinophils and mast cells with IC₅₀ values of 530 nM and 138 nM, respectively .

HY-107558

JNJ10191584 maleate VUF6002 maleate	Histamine Receptor	Neurological Disease
JNJ10191584 (VUF6002) maleate (compound 40) is an orally active and selective histamine H₄ receptor antagonist with a K_i value of 26 nM. JNJ10191584 maleate shows 540-fold selectivity to H₄ receptor over the H₃ receptor with a K_i value of 14.1 μM. JNJ10191584 maleate inhibits chemotaxis of eosinophils and mast cells with IC₅₀ values of 530 nM and 138 nM, respectively .

HY-N11691

Thapsigargicin Thapsigargicine	Others	Inflammation/Immunology
Thapsigargicin (Thapsigargicine) is a activator of mast cells and leukocytes. Thapsigargicin induces histamine release from rat peritoneal mast cells and human basophil leukocytes. Thapsigargicin increases the cytoplasmic free calcium level in intact human blood platelets .

HY-N8593

Undecane	TNF Receptor	Infection
Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α ^[

HY-P2706

Granuliberin R	Histamine Receptor	Endocrinology
Granuliberin R is a new mast cell degranulating peptide comes from amphibian, can be isolated from the skin of frog Rana rugosa. Granuliberin R is a dodecapeptide, can act on rat peritoneal mast cell to liberate granules and release histamine .

HY-N4207

Cnidicin	Others	Others
Cnidicin, a coumarin, inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells .

HY-101810

Tazanolast TO 188; Tazalest; Tazanol	Others	Inflammation/Immunology
Tazanolast is a selective mast-cell-stabilizing agent, on ozone-induced airway hyperresponsiveness in guinea pigs.

HY-124252

5,8,11-Eicosatriynoic acid ETI	Lipoxygenase	Cancer
5,8,11-Eicosatriynoic acid (ETI) is a lipoxygenase inhibitor that blocks LTC4 biosynthesis in mast cell tumor cells .

HY-B0538A

Pemirolast potassium TWT-8152; BMY 26517	Histamine Receptor	Inflammation/Immunology Endocrinology
Pemirolast potassium (TWT-8152) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.

HY-P2442

Bombolitin V	Bacterial	Others
Bombolitin V is a potent antimicrobial peptide with an ED ⁵⁰ value of 2 micrograms/ml in causing mast cell degranulation .

HY-N8593S

Undecane-d24	TNF Receptor	Infection
Undecane-d₂₄ is the deuterium labeled Undecane[1]. Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α[2].

HY-P4580

Suc-Ala-Ala-Pro-Phe-SBzl	Proteasome	Others
Suc-Ala-Ala-Pro-Phe-SBzl can be used as the substrate of rat intestinal mast cell protease (RMCP I), rat skeletal muscle mast cell protease (RMCP II) and Chymotrypsin (HY-108910). Suc-Ala-Ala-Pro-Phe-SBzl can be hydrolyzed by glycine (R208G) .

HY-N2095

Atractylone Atractylon	Influenza Virus	Infection Inflammation/Immunology
Atractylone (Atractylon) is a sesquiterpenoid extracted from Atractylodis Rhizoma. Atractylone (Atractylon) alleviates influenza A virus (IAV)-induced lung injury via regulating the TLR7 signaling pathway, and acts as a promising agent for IAV treatment. Atractylone (Atractylon) inhibits the degranulation of mast cell and exhibits potential for the treatment of mast cell-mediated allergic reactions .

HY-N8593R

Undecane (Standard)	TNF Receptor	Infection
Undecane (Standard) is the analytical standard of Undecane. This product is intended for research and analytical applications. Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α[

HY-16289

Lodoxamide tromethamine U-42585E	Histamine Receptor	Inflammation/Immunology Endocrinology
Lodoxamide tromethamine (U-42585E) is a medication for the treatment of prophylaxis of mast cell-mediated allergic disease.

HY-100269

Chymase-IN-1	Others	Inflammation/Immunology
Chymase-IN-1 is a potent, selective, orally active, nonpeptide inhibitor of human mast cell chymase with an IC₅₀ of 29 nM.

HY-W062109S

Olopatadine-d6	Histamine Receptor Endogenous Metabolite	Inflammation/Immunology
Olopatadine-d₆ is the deuterium labeled Olopatadine[1]. Olopatadine is an orally active and selective histamine 1 (H1) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic conjunctivitis[2][3].

HY-14270

Lodoxamide U-42585E free acid	Histamine Receptor	Inflammation/Immunology Endocrinology
Lodoxamide (U-42585E free acid) is an antiallergic compound acting as a mast-cell stabilizer for the treatment of asthma and allergic conjunctivitis.

HY-105999B

APC 366 TFA	Others	Others
APC 366 (TFA) is an irreversible mast cell tryptase inhibitor. APC 366 (TFA) can be used for the research of allergic diseases .

HY-N4207R

Cnidicin (Standard)	Others	Others
Cnidicin (Standard) is the analytical standard of Cnidicin. This product is intended for research and analytical applications. Cnidicin, a coumarin, inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells .

HY-N12295

Ciwujianoside D1	Others	Inflammation/Immunology
Ciwujianoside D1 is a natural product that can inhibit histamine release induced by anti-immunoglobulin E from rat peritoneal mast cells .

HY-B1619

Cromolyn 3 Publications Verification Cromoglicic acid	Others	Inflammation/Immunology
Cromolyn is a mast cell stabilizer. Cromolyn has the potential for the research of bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis .

HY-148244

MS47134 1 Publications Verification	Mas-related G-protein-coupled Receptor (MRGPR)	Others
MS47134 is a potent and selective MRGPRX4 agonist with an EC₅₀ value of 149 nM. MS47134 can be used for research of pain, itch and mast cell-mediated hypersensitivity .

HY-122161

JNJ-10311795 RWJ-355871	Cathepsin	Inflammation/Immunology
JNJ-10311795 (RWJ-355871), a potent dual inhibitor of neutrophil cathepsin G (K_i = 38 nM) and mast cell chymase (K_i = 2.3 nM), exhibits noteworthy antiinflammatory activity .

Cat. No.	Product Name	Type

HY-D0220A

Toluidine Blue (purity 36%)

Toluidine Blue O (purity 36%)

Dyes

Toluidine Blue (Toluidine Blue O) purity 36% is an alkaline quinonimine dye (vivo dye) with high affinity for acidic tissue components, staining nuclei blue and polysaccharides purple. Toluidine Blue purity 36% shows heterostaining properties for mast cells, mucins and chondrocytes. Toluidine Blue purity 36% can stain different components of plant tissues and cells in different colours. Toluidine Blue purity 36% is also used as a diagnostic aid to identify malignant lesions, such as cancer .

HY-W250143

Toluidine blue (ZnCl2)

Dyes

Toluidine blue (ZnCl2) is a basic thiazine dye commonly used as a biological stain for microscopy. It has a deep bluish-purple color and is commonly used to stain nucleic acids such as DNA and RNA, as well as to stain mast cells, cartilage, and other connective tissues. Toluidine blue (ZnCl2) stains the acidic components of these tissues, such as sulfated or carboxylated mucopolysaccharides. It is frequently used in histology, cytology, and pathology applications to aid in the diagnosis of various diseases and conditions. The dye is usually applied to tissue sections prior to microscopic examination and can be differentiated using an acidic alcohol solution. Toluidine blue (ZnCl2) is a relatively simple and inexpensive stain with good reproducibility, making it a popular choice for many laboratories.

Cat. No.	Product Name	Type

HY-E70177

N-Deacetylase/N-Sulfotransferase 2 EC:2.8.2.8; NDST2; N-HSST 2	Enzyme Substrates
N-Deacetylase/N-Sulfotransferase 2 is a sulfotransferase. N-Deacetylase/N-Sulfotransferase 2 synthesizes serglycin-bound heparin chains in mast cells .

Cat. No.	Product Name	Target	Research Area

HY-12537

Peptide 401	Histamine Receptor 5-HT Receptor	Inflammation/Immunology Endocrinology
Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT).

HY-106178

PMX-53 4 Publications Verification 3D53	Complement System	Cardiovascular Disease Inflammation/Immunology Cancer
PMX-53 (3D53) is a synthetic peptidic and a potent and orally active complement C5a receptor (CD88) antagonist with an IC₅₀ of 20 nM. PMX-53 is also a low-affinity MrgX2 agonist that stimulates MrgX2-mediated mast cell degranulation. PMX-53 specifically binds to C5aR1 and does not bind to the second C5aR (C5L2) and C3aR. PMX-53 has anti-inflammatory, anticancer and antiatherosclerotic effects .

HY-P1807

Mast Cell Degranulating Peptide HR-2	Histamine Receptor	Inflammation/Immunology
Mast Cell Degranulating Peptide HR-2, a 14-membered linear peptide isolated from the venom of the giant hornet Vespa orientalis, is capable of degranulating mast cells and thus initiating histamine release .

HY-P1987

Mast cell degranulating peptide (28-49)	Peptides	Neurological Disease
Mast cell degranulating peptide (28-49) is a depolarizing agent from bee venom, it can raise the content of cGMP level in mouse cerebellar slices .

HY-P5717

Peptide 12d	Peptides	Infection
Peptide 12d is an antimicrobial peptide isolated from the venom of wasp. Peptide 12d mediates antimicrobial response by stimulating mast cell degranulation .

HY-P2706

Granuliberin R	Histamine Receptor	Endocrinology
Granuliberin R is a new mast cell degranulating peptide comes from amphibian, can be isolated from the skin of frog Rana rugosa. Granuliberin R is a dodecapeptide, can act on rat peritoneal mast cell to liberate granules and release histamine .

HY-P2442

Bombolitin V	Bacterial	Others
Bombolitin V is a potent antimicrobial peptide with an ED ⁵⁰ value of 2 micrograms/ml in causing mast cell degranulation .

HY-P4580

Suc-Ala-Ala-Pro-Phe-SBzl	Proteasome	Others
Suc-Ala-Ala-Pro-Phe-SBzl can be used as the substrate of rat intestinal mast cell protease (RMCP I), rat skeletal muscle mast cell protease (RMCP II) and Chymotrypsin (HY-108910). Suc-Ala-Ala-Pro-Phe-SBzl can be hydrolyzed by glycine (R208G) .

HY-P5727

HR1	Peptides	Infection
HR1 is a mastoid protease. HR1 can increase the permeability of human erythrocyte membrane. HR1 can induce cytoplasmic membrane permeation in bacteria and mast cells .

HY-P3837

Xenopsin-Related Peptide 2 XP-2	Peptides	Metabolic Disease
Xenopsin-Related Peptide 2 (XP-2) is an avian counterpart to amphibian Xenopsin (HY-P0253). Xenopsin-Related Peptide 2 displays abilities to release histamine from isolated rat mast cells and is as effective as synthetic Bradykinin (HY-P0206) .

HY-P5357

SFNGGP-NH2	Protease Activated Receptor (PAR)	Others
SFNGGP-NH2 is a biological active peptide. (PAR-3 is a high-affinity thrombin receptor. PAR-3 mRNA is expressed in the cutaneous mast cells of humans. Protease-Activated Receptors (PARs) have been studied for their roles in itch and their itch-associated response through histamine-dependent/independent pathways have been reported. PAR-3 has been shown not to induce itching alone but possibly in conjunction with PAR-4. Co-expression of PAR-3 and PAR-4 enhances thrombin action suggesting that PAR-3 alone does not mediate transmembrane signaling but instead functions as a cofactor to activate PAR-4.)

Cat. No.	Product Name	Target	Research Area

HY-P99193

Enokizumab MEDI-528	Interleukin Related	Inflammation/Immunology
Enokizumab (MEDI-528) is a monoclonal antibody targeting to interleukin (IL)-9. IL-9 regulates the development of airway inflammation, mucus production, airway hyperresponsiveness, and airway fibrosis largely by increasing mast cell numbers and activity in the airways .

HY-P99371

Lirentelimab AK002; Anti-Siglec-8 Reference Antibody (lirentelimab)	Apoptosis	Inflammation/Immunology
Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis .

HY-P99462

Barzolvolimab CDX 0159	c-Kit	Inflammation/Immunology
Barzolvolimab (CDX 0159) is a humanized anti-KIT IgG1 monoclonal antibody. Barzolvolimab specificity and potently inhibits KIT activation by SCF. Barzolvolimab can reduce skin mast cells and disease activity in chronic inducible urticaria .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7885

(25R)-Spirost-4-ene-3,12-dione (-)-(25R)-Spirost-4-ene-3,12-dione	Natural Products Polygonum chinense Linn. Polygonaceae Source classification Plants	Others
(25R)-Spirost-4-ene-3,12-dione ((-)-(25R)-Spirost-4-ene-3,12-dione) is a natural product that has an inhibitory effect on neutrophil superoxide anion production and histamine release from mast cells .

HY-B0157A

Ketotifen fumarate 3 Publications Verification HC 20511 fumarate	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Histamine Receptor Endogenous Metabolite SARS-CoV Influenza Virus
Ketotifen (HC 20-511) fumarate is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen fumarate can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen fumarate also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen fumarate can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention .

HY-B0157

Ketotifen 3 Publications Verification HC 20-511	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Endocrinology	Endogenous Metabolite Histamine Receptor SARS-CoV Influenza Virus
Ketotifen (HC 20-511) is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention .

HY-D0220A

Toluidine Blue (purity 36%) Toluidine Blue O (purity 36%)	Classification of Application Fields Disease Research Fields Cancer	Fluorescent Dye
Toluidine Blue (Toluidine Blue O) purity 36% is an alkaline quinonimine dye (vivo dye) with high affinity for acidic tissue components, staining nuclei blue and polysaccharides purple. Toluidine Blue purity 36% shows heterostaining properties for mast cells, mucins and chondrocytes. Toluidine Blue purity 36% can stain different components of plant tissues and cells in different colours. Toluidine Blue purity 36% is also used as a diagnostic aid to identify malignant lesions, such as cancer .

HY-P1987

Mast cell degranulating peptide (28-49)	Natural Products Animals Source classification	Others
Mast cell degranulating peptide (28-49) is a depolarizing agent from bee venom, it can raise the content of cGMP level in mouse cerebellar slices .

HY-W062109

Olopatadine	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Histamine Receptor
Olopatadine is an orally active and selective histamine 1 (H₁) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic conjunctivitis .

HY-122295

Dehydroleucodine	Structural Classification other families Artemisia douglasiana Classification of Application Fields Source classification Plants Inflammation/Immunology Disease Research Fields	Apoptosis
Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana. Dehydroleucodine is a mast cell stabilizer that inhibits tmast cell degranulation induced by compound 48/80. Dehydroleucodine inudces cells apoptosis, and has gastric ulcer inhibition and antileukemic effects .

HY-N3007A

(E)-Naringenin chalcone	Structural Classification Phenols Polyphenols Solanum lycopersicum L. Solanaceae Plants	Others
(E)-Naringenin chalcone is an orally active anti-allergic agent. (E)-Naringenin chalcone also has antioxidant, anti-inflammatory activities. (E)-Naringenin chalcone can improve adipocyte functions. (E)-Naringenin chalcone inhibits histamine release from rat peritoneal mast cell .

HY-B0157AR

Ketotifen fumarate (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Histamine Receptor Endogenous Metabolite SARS-CoV Influenza Virus
Ketotifen (fumarate) (Standard) is the analytical standard of Ketotifen (fumarate). This product is intended for research and analytical applications. Ketotifen (HC 20-511) fumarate is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen fumarate can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen fumarate also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen fumarate can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention .

HY-N11691

Thapsigargicin Thapsigargicine	Structural Classification Terpenoids Source classification Diterpenoids Plants Umbelliferae Glechoma hederacea L.	Others
Thapsigargicin (Thapsigargicine) is a activator of mast cells and leukocytes. Thapsigargicin induces histamine release from rat peritoneal mast cells and human basophil leukocytes. Thapsigargicin increases the cytoplasmic free calcium level in intact human blood platelets .

HY-N8593

Undecane	Infection Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	TNF Receptor
Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α ^[

HY-N4207

Cnidicin	Structural Classification Classification of Application Fields Source classification Other Diseases Coumarins Phenylpropanoids Umbelliferae Plants Disease Research Fields Echinacea angustifolia DC.	Others
Cnidicin, a coumarin, inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells .

HY-N2095

Atractylone Atractylon	Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Source classification Plants Compositae Inflammation/Immunology Disease Research Fields Erythrina sigmoidea Hua	Influenza Virus
Atractylone (Atractylon) is a sesquiterpenoid extracted from Atractylodis Rhizoma. Atractylone (Atractylon) alleviates influenza A virus (IAV)-induced lung injury via regulating the TLR7 signaling pathway, and acts as a promising agent for IAV treatment. Atractylone (Atractylon) inhibits the degranulation of mast cell and exhibits potential for the treatment of mast cell-mediated allergic reactions .

HY-N8593R

Undecane (Standard)	Structural Classification Natural Products Microorganisms Source classification	TNF Receptor
Undecane (Standard) is the analytical standard of Undecane. This product is intended for research and analytical applications. Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α[

HY-N4207R

Cnidicin (Standard)	Structural Classification Source classification Coumarins Phenylpropanoids Umbelliferae Plants Echinacea angustifolia DC.	Others
Cnidicin (Standard) is the analytical standard of Cnidicin. This product is intended for research and analytical applications. Cnidicin, a coumarin, inhibits the degranulation of mast cell and the nitric oxide (NO) generation in RAW 264.7 cells .

HY-N12295

Ciwujianoside D1	Triterpenes Structural Classification Polysaccharides Terpenoids Source classification Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Saccharides Araliaceae	Others
Ciwujianoside D1 is a natural product that can inhibit histamine release induced by anti-immunoglobulin E from rat peritoneal mast cells .

HY-N12254

Natsudaidain	Structural Classification Flavonols Flavonoids Source classification Rutaceae Citrus japonica Thunb. Plants	p38 MAPK
Natsudaidain is a kind of polymethoxyflavone. Natsudaidain can be isolated from Citrus plants. Natsudaidain inhibits tumor necrosis factor-α and cyclooxygenase-2 production n by suppressing p38 MAPK phosphorylation on mast cells .

HY-124257

(R)-Citronellol D-Citronellol; (R)-(+)-β-Citronellol	Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Source classification Pelargonium hortorum Plants Endogenous metabolite Geraniaceae Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
(R)-Citronellol (D-Citronellol) is an alcoholic monoterpene found in geranium essential oil. (R)-Citronellol inhibits degranulation of mast cells and does not affect caffeine bitterness perception. (R)-Citronellol can be used in decorative cosmetics, toiletries as well as in non-cosmetic products .

HY-110013

Terreic acid	Microorganisms Source classification	Btk Antibiotic
Terreic acid, a quinone epoxide antibiotic, acts as an effective Btk inhibitor. Terreic acid blocks the interaction between PKC and the pleckstrin homology domain of Btk. Terreic acid inhibits the binding of GST-BtkPH to PKC in lysates of HMC-1 human mast cells with an IC₅₀ of approximately 100 μM .

HY-19839

Ansamitocin P 3' Antibiotic C 15003P3'; Maytansinol butyrate	Structural Classification Microorganisms Antibiotics Source classification	Antibiotic
Ansamitocin P 3' (Antibiotic C 15003P3') is an anti-tumor antibiotic. Ansamitocin P 3' prolongs the survival of mice with leukemia P388, melanoma B16, leukemia L1210, sarcoma 180, Ehrlich carcinoma and mast cell tumor P815 .

HY-N10182

Spinacetin	Phyllodium pulchellum (L.) Desv. Structural Classification Flavonols Flavonoids Source classification Plants Compositae	Histamine Receptor
Spinacetin is a natural product that can be isolated from Inula japonica. Spinacetin inhibits the release of histamine. Spinacetin has anti-inflammatory activity .

HY-N3421

Koaburaside	Structural Classification Eucommia ulmoides Oliver Source classification Eucommiaceae Plants Saccharides Monosaccharides	Interleukin Related TNF Receptor Influenza Virus
Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC₅₀ of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase .

HY-N4126

6-Demethoxytangeretin	Flavonoids other families Neurological Disease Classification of Application Fields Flavones Source classification Rutaceae Plants Inflammation/Immunology Disease Research Fields Citrus reticulata Blanco Cancer	Anaplastic lymphoma kinase (ALK)
6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus reticulata. 6-Demethoxytangeretin exerts anti-inflammatory activity and anti-allergic activity, suppresses production and gene expression of interleukin-6 in human mast cell-1 via anaplastic lymphoma kinase (ALK) and mitogen-activated protein kinase (MAPK) pathways . 6-Demethoxytangeretin facilitates the CRE-mediated transcription associated with learning and memory in cultured hippocampal neurons .

HY-N0631

Cornuside 2 Publications Verification	Structural Classification Iridoids Cornaceae Classification of Application Fields Cornus officinalis Sieb. et Zucc. Terpenoids Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	p38 MAPK NF-κB
Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis Sieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Cornuside has anti-allergic effects in vivo and in vitro which suggests a therapeutic application of this agent in inflammatory allergic diseases .

HY-103183

CV1808 2-Phenylaminoadenosine	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Adenosine Receptor Endogenous Metabolite
CV1808 (2-Phenylaminoadenosine) is a non-selective A2 adenosine receptor (A2 AR) agonist with K_is of 76 and 1450 nM for A2A and A3 adenosine receptor subtypes, respectively .

HY-N0631R

Cornuside (Standard)	Structural Classification Iridoids Cornaceae Cornus officinalis Sieb. et Zucc. Terpenoids Source classification Phenols Polyphenols Plants	p38 MAPK NF-κB
Cornuside (Standard) is the analytical standard of Cornuside. This product is intended for research and analytical applications. Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis Sieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Cornuside has anti-allergic effects in vivo and in vitro which suggests a therapeutic application of this agent in inflammatory allergic diseases .

HY-N7292

Bakkenolide B	Other Terpenoids Classification of Application Fields Terpenoids Source classification Plants Compositae Disease Research Fields Inflammation/Immunology Piptadenia Benth.	Others
Bakkenolide B is isolated from petasites japonicas leaves and has anti-allergic and anti-inflammatory effects. Bakkenolide B can be used for the study of asthma .

HY-Y0320

Dimethyl sulfoxide Maximum Cited Publications 132 Publications Verification DMSO	Classification of Application Fields Disease Research Fields Cancer	Bacterial Cholinesterase (ChE)
Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties . MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition).

HY-114203

Eckol	Eisenia bicyclis Structural Classification other families Source classification Phenols Polyphenols Plants	Monoamine Oxidase Influenza Virus
Eckol is a potent hMAO-A (Mixed) and hMAO-B (non-competitive) inhibitor with IC₅₀s of 7.20 and 83.44 μM, respectively. Eckol shows stimulatory effects in maize and can be used as a plant biostimulant. Eckol also shows antiallergic and antiviral effects .

Species:	Human (20) Rhesus Macaque (2) Mouse (16) Rat (5) Canine (2)
Tag:	His (27) SUMO (1) Tag Free (11) GST (1) Fc (6) Flag (1)
Source:	HEK293 (18) Sf9 insect cells (1) CHO (1) P. pastoris (4) Sf9 insect cells (4) E. coli (17)

Cat. No.	Compare	Product Name	Species	Source

HY-P77078

	Mast Cell Protease-1/MCPT-1 Protein, Mouse (HEK293, His) mast cell protease 1; mMCP-1; Mcpt1	Mouse	HEK293
	Mast Cell Protease-1 (MCPT-1) displays chymotrypsin-like enzymatic activity.Mast Cell Protease-1/MCPT-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Mast Cell Protease-1/MCPT-1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P72290

	Chymase/CMA1 Protein, Mouse (His) Alpha-chymase; mast cell chymase 1; mast cell protease 5; mMCP-5; mast cell protease I	Mouse	E. coli
	Chymase/CMA1 Protein, a prominent secreted protease in mast cells, is implicated in various physiological processes, including the generation of vasoactive peptides, extracellular matrix degradation, and the regulation of gland secretion.Chymase/CMA1 Protein, Mouse (His) is the recombinant mouse-derived Chymase/CMA1 protein, expressed by E.coli , with N-His labeled tag.

HY-P74252

	Chymase/CMA1 Protein, Human (sf9, His) Alpha-chymase; mast cell chymase 1; mast cell protease 5; mMCP-5	Human	Sf9 insect cells
	Chymase/CMA1 Protein, a secreted protease from mast cells, plays a significant role in generating vasoactive peptides, degrading the extracellular matrix, and regulating gland secretion. Chymase/CMA1 Protein, Human (sf9, His) is the recombinant human-derived Chymase/CMA1 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Chymase/CMA1 Protein, Human (sf9, His) is 247 a.a., with molecular weight of ~33 kDa.

HY-P79111

	SCF Protein, Canine Kit ligand; mast cell growth factor; MGF; Stem cell Factor; SCF; c-Kit ligand; KITLG	Canine	E. coli
	SCF protein critically promotes mast cell proliferation, enhancing both myeloid and lymphoid hematopoietic progenitor proliferation in bone marrow. Additionally, SCF facilitates cell-cell adhesion and synergizes with other cytokines, potentially interleukins. As a homodimer, SCF is connected non-covalently, contributing to hematopoietic processes and immune responses. SCF Protein, Canine is the recombinant canine-derived SCF protein, expressed by E. coli , with tag free. The total length of SCF Protein, Canine is 165 a.a., with molecular weight of ~19 kDa.

HY-P7216

	IL-3 Protein, Canine rCaIL-3; mast cell growth factor; MCGF; Hematopoietic growth factor	Canine	E. coli
	IL-3 Protein, Canine is a hemopoietic growth factor involved in the survival, proliferation and differentiation of multipotent hemopoietic cells.

HY-P70528

	SCF Protein, Mouse Kit ligand; Hematopoietic growth factor KL; mast cell growth factor; MGF; Steel factor; Stem cell factor; SCF	Mouse	E. coli
	SCF proteins are ligands for the KIT receptor-type protein tyrosine kinase and are critical for multiple cellular processes, including survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis.Binding to KIT activates multiple signaling pathways involving PIK3R1, AKT1, GRB2, RAS, RAF1, MAP kinase, STAT family members and PLCG1, producing signaling molecules.SCF Protein, Mouse is the recombinant mouse-derived SCF protein, expressed by E.coli , with tag free.

HY-P70781

	SCF Protein, Human 3 Publications Verification Kit Ligand; mast cell Growth Factor; MGF; Stem cell Factor; SCF; c-Kit ligand; KITLG; MGF; SCF	Human	E. coli
	SCF, Human, as a recombinant protein, plays essential roles in gametogenesis, melanogenesis and hematopoiesis. SCF, Human also plays an important role in nervous system.

HY-P7064

	SCF Protein, Mouse (P.pastoris) rMuSCF; Hematopoietic growth factor KL; MGF; mast cell Growth Factor	Mouse	P. pastoris
	SCF Protein, Mouse (P.pastoris) is the ligand for the receptor-type protein-tyrosine kinase KIT.It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.

HY-P702794

	CPA3 Protein, Human (His) carboxypeptidase A; carboxypeptidase A3 (mast cell); Carboxypeptidase A3; carboxypeptidase A3 mast cell; CBPA3_HUMAN; Cpa3; mast cell carboxypeptidase A; mast cell carboxypeptidase A3; MC CPA; MC-CPA; tissue carboxypeptidase A	Human	E. coli
	CPA3 Protein, Human (His) is the recombinant human-derived CPA3, expressed by E. coli , with N-6*His labeled tag. The total length of CPA3 Protein, Human (His) is 308 a.a.,

HY-P702795

	CPA3 Protein, Human (P.pastoris, His) carboxypeptidase A; carboxypeptidase A3 (mast cell); Carboxypeptidase A3; carboxypeptidase A3 mast cell; CBPA3_HUMAN; Cpa3; mast cell carboxypeptidase A; mast cell carboxypeptidase A3; MC CPA; MC-CPA; tissue carboxypeptidase A	Human	P. pastoris
	CPA3 Protein, Human (P.pastoris, His) is the recombinant human-derived CPA3, expressed by P. pastoris , with N-6*His labeled tag. The total length of CPA3 Protein, Human (P.pastoris, His) is 308 a.a.,

HY-P7056

	SCF Protein, Human (P.pastoris) rHuSCF; Hematopoietic growth factor KL; MGF; mast cell Growth Factor	Human	P. pastoris
	SCF Protein, Human (P.pastoris), the c-kit ligand, is a two disulfide bridge-containing cytokine in the regulation of the development and function of hematopoietic cell lineages and other cells such as mast cells, germ cells, and melanocytes.

HY-P7107

	SCF Protein, Rat (P.pastoris) rRtSCF; Hematopoietic growth factor KL; MGF; mast cell Growth Factor	Rat	P. pastoris
	SCF Protein, Rat (P.pastoris) is a hematopoietic cytokine, triggered by binding to its ligand c-kit, and plays an important role in hematopoiesis, spermatogenesis, and melanogenesis.

HY-P7107A

	SCF Protein, Rat (HEK293) rRtSCF; Hematopoietic growth factor KL; MGF; mast cell Growth Factor	Rat	HEK293
	SCF Protein, Rat (HEK293) is a hematopoietic cytokine, triggered by binding to its ligand c-kit, and plays an important role in hematopoiesis, spermatogenesis, and melanogenesis.

HY-P7040

	IL-3 Protein, Human rHuIL-3; Hematopoietic growth factor; mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor	Human	E. coli
	IL-3 Protein, Human is a multilineage hematopoietic cytokine with promising effects on platelet and neutrophil counts and special usefulness in patients with secondary hematopoietic failure.

HY-P7062

	IL-3 Protein, Mouse rMuIL-3; Hematopoietic growth factor; mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor	Mouse	E. coli
	IL-3 Protein, Mouse functions via specific cell surface receptors to stimulate the proliferation, differentiation and survival of haematopoietic cell lines.

HY-P73410

	SCF Protein, Human (sf9, His) SCF; Hematopoietic growth factor KL; MGF; mast cell Growth Factor	Human	Sf9 insect cells
	SCF proteins are ligands for the KIT receptor-type protein tyrosine kinase and regulate a variety of cellular processes, including survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Binding to KIT activates signaling pathways involving PIK3R1, AKT1, GRB2, RAS, RAF1, MAP kinase, STAT family members, and PLCG1, producing diacylglycerol and inositol 1,4,5-trisphosphate. SCF Protein, Human (sf9, His) is the recombinant human-derived SCF protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P73662

	SCF Protein, Mouse (sf9, His) SCF; Hematopoietic growth factor KL; MGF; mast cell Growth Factor	Mouse	Sf9 insect cells
	SCF proteins are ligands for the KIT receptor-type protein tyrosine kinase and are critical for multiple cellular processes, including survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis.Binding to KIT activates multiple signaling pathways involving PIK3R1, AKT1, GRB2, RAS, RAF1, MAP kinase, STAT family members and PLCG1, producing signaling molecules.SCF Protein, Mouse (sf9, His) is the recombinant mouse-derived SCF protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P7040A

	IL-3 Protein, Human (CHO) 1 Publications Verification rHuIL-3; Hematopoietic growth factor; mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor	Human	CHO
	IL-3 Protein, Human (CHO) is a multilineage hematopoietic cytokine with promising effects on platelet and neutrophil counts and special usefulness in patients with secondary hematopoietic failure.

HY-P7062A

	IL-3 Protein, Mouse (His) rMuIL-3; Hematopoietic growth factor; mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor	Mouse	E. coli
	IL-3 Protein, Mouse (His) is a pleiotropic cytokine containing 135 amino acids, which functions via specific cell surface receptors to stimulate the proliferation, differentiation and survival of haematopoietic cell lines.

HY-P70757

	SCF Protein, Human (HEK293, His) Kit Ligand; mast cell Growth Factor; MGF; Stem cell Factor; SCF; c-Kit ligand; KITLG; MGF; SCF	Human	HEK293
	SCF proteins are ligands for the KIT receptor-type protein tyrosine kinase and regulate a variety of cellular processes, including survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Binding to KIT activates signaling pathways involving PIK3R1, AKT1, GRB2, RAS, RAF1, MAP kinase, STAT family members, and PLCG1, producing diacylglycerol and inositol 1,4,5-trisphosphate. SCF Protein, Human (HEK293, His) is the recombinant human-derived SCF protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P700148AF

	Animal-Free SCF Protein, Human (His) Kit Ligand; mast cell Growth Factor; MGF; Stem cell Factor; SCF; c-Kit ligand; KITLG; MGF; SCF	Human	E. coli
	SCF proteins are ligands for the KIT receptor-type protein tyrosine kinase and regulate a variety of cellular processes, including survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Binding to KIT activates signaling pathways involving PIK3R1, AKT1, GRB2, RAS, RAF1, MAP kinase, STAT family members, and PLCG1, producing diacylglycerol and inositol 1,4,5-trisphosphate. Animal-Free SCF Protein, Human (His) is the recombinant human-derived animal-FreeSCF protein, expressed by E. coli , with C-His labeled tag.

HY-P77529

	SCF Protein, Mouse (Biotinylated, sf9, His) SCF; Hematopoietic growth factor KL; MGF; mast cell Growth Factor	Mouse	Sf9 insect cells
	SCF proteins are ligands for the KIT receptor-type protein tyrosine kinase and are critical for multiple cellular processes, including survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis.Binding to KIT activates multiple signaling pathways involving PIK3R1, AKT1, GRB2, RAS, RAF1, MAP kinase, STAT family members and PLCG1, producing signaling molecules.SCF Protein, Mouse (Biotinylated, sf9, His) is the recombinant mouse-derived SCF protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P70576AF

	Animal-Free IL-3 Protein, Human (His) rHuIL-3; Hematopoietic growth factor; mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor	Human	E. coli
	Animal-Free IL-3 Protein, Human (His) is the recombinant human-derived animal-FreeIL-3 protein, expressed by E. coli , with C-His labeled tag. , has molecular weight of ~16 kDa.

HY-P700205AF

	Animal-Free IL-3 Protein, Mouse (His) rMuIL-3; Hematopoietic growth factor; mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor	Mouse	E. coli
	IL-3 protein is secreted by T lymphocytes, mast cells and osteoblasts.It plays an important regulatory role in hematopoietic progenitor cells and stimulates mature basophils, eosinophils and monocytes.In addition to hematopoiesis, it supports neuronal cell proliferation, survival, and bone homeostasis by inhibiting osteoclast differentiation.Animal-Free IL-3 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-3 protein, expressed by E.coli , with C-His labeled tag.

HY-P77080

	MCEMP1 Protein, Human (HEK293, Fc) mast cell-expressed membrane protein 1; C19orf59	Human	HEK293
	MCEMP1, a lung-specific surface protein, is a type II transmembran protein. MCEMP1 is primarily expressed in myeloid lineage immune cells and plays a critical in allergic and inflammatory lung diseases. MCEMP1 is an adaptor for KIT receptor to promotes stem cell factor-mediated mast cell proliferation. MCEMP1 also participates in the chemotaxis, adhesion, and migration of circulating monocytes. MCEMP1 Protein, Human (HEK293, Fc) is the recombinant human-derived MCEMP1 protein, expressed by HEK293 , with N-mFc labeled tag. The total length of MCEMP1 Protein, Human (HEK293, Fc) is 81 a.a., with molecular weight of 40-50 kDa.

HY-P70576

	IL-3 Protein, Human (His) 1 Publications Verification Interleukin-3; IL-3; Hematopoietic Growth Factor; mast cell Growth Factor; MCGF; Multipotential Colony-Stimulating Factor; P-cell-Stimulating Factor; IL3	Human	E. coli
	IL-3 protein is mainly secreted by T lymphocytes, mast cells and osteoblasts and is critical for the generation and differentiation of hematopoietic progenitor cells. It stimulates mature basophils, eosinophils and monocytes, promoting functional activation. IL-3 Protein, Human (His) is the recombinant human-derived IL-3 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70576G

	GMP IL-3 Protein, Human (His) Interleukin-3; IL-3; Hematopoietic Growth Factor; mast cell Growth Factor; MCGF; Multipotential Colony-Stimulating Factor; P-cell-Stimulating Factor; IL3	Human	E. coli
	IL-3 protein is mainly secreted by T lymphocytes, mast cells and osteoblasts and is critical for the generation and differentiation of hematopoietic progenitor cells. It stimulates mature basophils, eosinophils and monocytes, promoting functional activation. GMP IL-3 Protein, Human (His) is the recombinant human-derived IL-3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of GMP IL-3 Protein, Human (His) is 133 a.a., with molecular weight of 13-16 kDa.

HY-P71858A

	IL-3 Protein, Rhesus macaque (His) IL3; Interleukin-3; IL-3; Hematopoietic growth factor; mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor	Rhesus Macaque	E. coli
	IL-3 protein, a hematopoietic cytokine, regulates hematopoiesis by influencing the production, differentiation, and function of various white blood cell populations. It acts as a colony-stimulating factor, promoting the development and maturation of these cell types and maintaining a functional immune system. IL-3 Protein, Rhesus macaque (His) is the recombinant Rhesus Macaque-derived IL-3 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70765

	IL-3 Protein, Human (HEK293, His) 1 Publications Verification Interleukin-3; IL-3; Hematopoietic Growth Factor; mast cell Growth Factor; MCGF; Multipotential Colony-Stimulating Factor; P-cell-Stimulating Factor; IL3	Human	HEK293
	IL-3 Protein, Human (HEK293, His) is a multipotent hematopoietic growth factor that can control blood formation. IL-3 Protein, Human (HEK293, His) is a recombinant human interleukin-3 (rhIL-3) expressed in HEK 293 cells with a His tag. rhIL-3 is also a weak inflammatory mediator. rhIL-3 can be used to improve states of hematopoietic failure.

HY-P72752

	CD117/c-kit Protein, Human (HEK293, His) mast/stem cell growth factor receptor Kit; SCFR; PBT; CD117; KIT	Human	HEK293
	CD117/c-kit is a tyrosine protein kinase receptor for KITLG/SCF that coordinates cell survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Upon KITLG/SCF binding, CD117 activates the pathway and phosphorylates PIK3R1, PLCG1, SH2B2/APS, and CBL. CD117/c-kit Protein, Human (HEK293, His) is the recombinant human-derived CD117/c-kit protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72879

	CD117/c-Kit Protein, Mouse (HEK293, Fc) mast/stem cell growth factor receptor Kit; SCFR; CD117; Kit; Sl	Mouse	HEK293
	CD117/c-Kit protein is a tyrosine protein kinase that acts as a cell surface receptor for KITLG/SCF and regulates cell survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, function, and melanogenesis . CD117/c-Kit Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD117/c-Kit protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72880

	CD117/c-Kit Protein, Mouse (HEK293, His) mast/stem cell growth factor receptor Kit; SCFR; CD117; Kit; Sl	Mouse	HEK293
	CD117/c-Kit protein is a tyrosine protein kinase that acts as a cell surface receptor for KITLG/SCF and regulates cell survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, function, and melanogenesis .CD117/c-Kit Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD117/c-Kit protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P74337

	CD117/c-kit Protein, Rat (HEK293, His) mast/stem cell growth factor receptor Kit; SCFR; CD117; Kit; Sl	Rat	HEK293
	CD117, also known as tyrosine-protein kinase KIT or mast/stem cell growth factor receptor (SCFR), is a cytokine receptor that is expressed on the surface of hematopoietic stem cells and other cell types. CD117 signaling pathway plays an important role in cell survival, proliferation and differentiation. CD117 is a proto-oncogene associated with tumor development. CD117/c-kit Protein, Rat (HEK293, His) is the recombinant rat-derived CD117/c-kit protein, expressed by HEK293 , with C-His labeled tag.

HY-P74338

	CD117/c-kit Protein, Rat (HEK293, Fc) mast/stem cell growth factor receptor Kit; SCFR; CD117; Kit; Sl	Rat	HEK293

HY-P74336

	CD117/c-kit Protein, Rhesus Macaque (HEK293, Fc) mast/stem cell growth factor receptor Kit; SCFR; CD117; Kit; Sl	Rhesus Macaque	HEK293
	CD117, also known as tyrosine-protein kinase KIT or mast/stem cell growth factor receptor (SCFR), is a cytokine receptor that is expressed on the surface of hematopoietic stem cells and other cell types. CD117 signaling pathway plays an important role in cell survival, proliferation and differentiation. CD117 is a proto-oncogene associated with tumor development. CD117/c-kit Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived CD117/c-kit protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P74341

	CD117/c-kit Protein, Human (141a.a, His) mast/stem cell growth factor receptor Kit; SCFR; CD117; Kit; Sl	Human	E. coli
	CD117/c-kit is a tyrosine protein kinase receptor for KITLG/SCF that coordinates cell survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Upon KITLG/SCF binding, CD117 activates the pathway and phosphorylates PIK3R1, PLCG1, SH2B2/APS, and CBL. CD117/c-kit Protein, Human (141a.a, His) is the recombinant human-derived CD117/c-kit protein, expressed by E. coli , with N-His labeled tag.

HY-P70555

	SCF Protein, Mouse (HEK293, His) 1 Publications Verification FPH2; KIT ligand; Kitl; KITLG; KL-1; mast cell growth factor; MGF; MGFSHEP7; SCF; SCFStem cell factor; SFc-Kit ligand; SLF; steel factor	Mouse	HEK293
	SCF proteins are ligands for the KIT receptor-type protein tyrosine kinase and are critical for multiple cellular processes, including survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis.Binding to KIT activates multiple signaling pathways involving PIK3R1, AKT1, GRB2, RAS, RAF1, MAP kinase, STAT family members and PLCG1, producing signaling molecules.SCF Protein, Mouse (HEK293, His) is the recombinant mouse-derived SCF protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70685

	IL-3 Protein, Mouse (HEK293, His) Interleukin-3; IL-3; Hematopoietic growth factor; Multipotential colony-stimulating factor; P-cell-stimulating factor; Il3; Il-3; mast cell growth factor; MCGF	Mouse	HEK293
	IL-3 Protein, Mouse (HEK293, His) is a multilineage hematopoietic cytokine with promising effects on platelet and neutrophil counts and special usefulness in patients with secondary hematopoietic failure.

HY-P71130

	SCF Protein, Rat (HEK293, His) FPH2; KIT ligand; Kitl; KITLG; KL-1; mast cell growth factor; MGF; MGFSHEP7; SCF; SCFStem cell factor; SFc-Kit ligand; SLF; steel factor	Rat	HEK293
	Stem cell factor (SCF), as a key ligand of KIT, regulates cell survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Binding to KIT activates signaling pathways involving phosphorylation events, key kinases (AKT1, RAS, RAF1, MAPK1/ERK2, MAPK3/ERK1), STAT family members, and PLCG1. SCF Protein, Rat (HEK293, His) is the recombinant rat-derived SCF protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71131

	Tryptase beta-2 Protein, Mouse (HEK293, His) 1 Publications Verification Tryptase beta-2; Tryptase-2; mast cell protease 6; mMCP-6	Mouse	HEK293
	Tryptase beta-2, a neutral protease abundant in mast cells, plays a key role in innate immunity.As the primary proteolytic enzyme released during mast cell activation, Tryptase beta-2 contributes significantly to immune functions.Its involvement underscores its importance in mediating cellular responses linked to innate immunity, highlighting its role in the intricate defense mechanisms of the immune system.Tryptase beta-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Tryptase beta-2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P73495

	CD117/c-kit Protein, Human (P10721-2, HEK293, His) mast/stem cell growth factor receptor Kit; SCFR; CD117; Kit; Sl	Human	HEK293
	CD117/c-kit is a tyrosine protein kinase receptor for KITLG/SCF that coordinates cell survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Upon KITLG/SCF binding, CD117 activates the pathway and phosphorylates PIK3R1, PLCG1, SH2B2/APS, and CBL. CD117/c-kit Protein, Human (P10721-2, HEK293, His) is the recombinant human-derived CD117/c-kit protein, expressed by HEK293 , with C-His labeled tag. The total length of CD117/c-kit Protein, Human (P10721-2, HEK293, His) is 491 a.a., with molecular weight of 75-85 kDa.

HY-P74339

	CD117/c-kit Protein, Human (P10721-2, HEK293, Fc) mast/stem cell growth factor receptor Kit; SCFR; CD117; Kit; Sl	Human	HEK293
	CD117/c-kit is a tyrosine protein kinase receptor for KITLG/SCF that coordinates cell survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Upon KITLG/SCF binding, CD117 activates the pathway and phosphorylates PIK3R1, PLCG1, SH2B2/APS, and CBL. CD117/c-kit Protein, Human (P10721-2, HEK293, Fc) is the recombinant human-derived CD117/c-kit protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD117/c-kit Protein, Human (P10721-2, HEK293, Fc) is 491 a.a., with molecular weight of 93-115 kDa.

HY-P76719

	Allergin-1 Protein, Mouse (HEK293, Fc) Allergy inhibitory receptor 1; mast cell antigen 32; MCA-32; Milr1; Gm885	Mouse	HEK293
	Allergin-1 protein, an immunoglobulin-like receptor, inhibits mast cell degranulation and suppresses hypersensitivity reactions. It interacts with tyrosine-phosphorylated proteins, such as PTPN6, PTPN11, and INPP5D, to fine-tune mast cell responses. Allergin-1 plays a pivotal role in regulating allergic reactions and hypersensitivity responses. Allergin-1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Allergin-1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P71598

	NLRP3 Protein, Mouse (His-SUMO) 1 Publications Verification Nlrp3; Cias1; Mmig1; Nalp3; Pypaf1; NACHT; LRR and PYD domains-containing protein 3; Cold autoinflammatory syndrome 1 protein homolog; Cryopyrin; mast cell maturation-associated-inducible protein 1; PYRIN-containing APAF1-like protein 1	Mouse	E. coli
	The NLRP3 protein acts as a sensor in the NLRP3 inflammasome, which is activated in response to membrane defects caused by pathogens or damage signals. It assembles the inflammasome complex, including NLRP3, CASP1, and PYCARD/ASC. NLRP3 Protein, Mouse (His-SUMO) is the recombinant mouse-derived NLRP3 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

HY-P702691

	CD117/c-kit Protein, Human (P10721-1, sf9) KIT; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; PBT, piebald trait; mast/stem cell growth factor receptor Kit; C Kit; CD117; SCFR; p145 c-kit; proto-oncogene c-Kit; piebald trait protein; soluble KIT variant 1; tyrosine-protein kinase Kit; proto-oncogene tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; PBT; C-Kit	Human	Sf9 insect cells
	CD117/c-kit is a tyrosine protein kinase receptor for KITLG/SCF that coordinates cell survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Upon KITLG/SCF binding, CD117 activates the pathway and phosphorylates PIK3R1, PLCG1, SH2B2/APS, and CBL. CD117/c-kit Protein, Human (P10721-1, sf9) is the recombinant human-derived CD117/c-kit, expressed by Sf9 insect cells , with GST, Flag labeled tag. The total length of CD117/c-kit Protein, Human (P10721-1, sf9) is 433 a.a.,

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Cat. No.	Product Name	Chemical Structure

HY-B0157AS

Ketotifen-d3 fumarate
Ketotifen-d₃ (fumarate) is the deuterium labeled Ketotifen fumarate. Ketotifen (HC 20511) fumarate is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, which is used to prevent asthma attacks[1][2].

HY-N8593S

Undecane-d24
Undecane-d₂₄ is the deuterium labeled Undecane[1]. Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α[2].

HY-W062109S

Olopatadine-d6
Olopatadine-d₆ is the deuterium labeled Olopatadine[1]. Olopatadine is an orally active and selective histamine 1 (H1) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic conjunctivitis[2][3].

HY-B1619S

Cromoglicic acid-d5
Cromoglicic acid-d₅ is the deuterium labeled Cromolyn[1]. Cromolyn is a mast cell stabilizer. Cromolyn has the potential for the research of bronchial asthma, allergic rhinitis, and certain allergic eye conditions such as vernal conjunctivitis, keratitis, and keratoconjunctivitis[2].

HY-B0640S

Epinastine-13C,d3 hydrobromide
Epinastine- ¹³C,d₃ (hydrobromide) is the ¹³C- and deuterium labeled Epinastine. Epinastine (WAL801) is an antihistamine and mast cell stabilizer. Epinastine is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine also inhibits IL-8 release and has an antiallergic action[1][2][3][4].

HY-10330S

Toceranib-d8
Toceranib-d₈ is the deuterium labeled Toceranib. Toceranib (SU11654) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively. Toceranib (SU11654) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors[1][2].

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HY-P81788

	Mast Cell Tryptase Antibody (YA1533) TPS1; TPS2; TPSAB1; TPSB1; MCP 7; mast cell protease 7; Tryptase alpha 1	WB, IHC-P, IP	Human, Mouse, Rat
	Mast Cell Tryptase Antibody (YA1533) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1533), targeting Mast Cell Tryptase, with a predicted molecular weight of 31 kDa. Mast Cell Tryptase Antibody (YA1533) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

HY-P81884

	Mast Cell Chymase Antibody (YA1629) Chymase 1; Chymase; CMA1; CYH; CYM; Mcp-5; MCP3P; Mcpt5; MCT1; MMCP-5	WB, IHC-P	Human
	Mast Cell Chymase Antibody (YA1629) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1629), targeting Mast Cell Chymase, with a predicted molecular weight of 27 kDa (observed band size: 27 kDa). Mast Cell Chymase Antibody (YA1629) can be used for WB, IHC-P experiment in human background.

HY-P81128

	SCF Antibody Stem cell Factor; C kit ligand; Ckit ligand; DKFZp686F2250; KIT ligand; Kitl; KITLG; KL 1; KL1; mast cell growth factor; MGF; SF; SHEP7; Steel factor; Stem cell factor precursor; SCF_HUMAN.	WB, IHC-P, ICC/IF, FC	Human
	SCF Antibody is an unconjugated, approximately 31 kDa, rabbit-derived, anti-SCF monoclonal antibody. SCF Antibody can be used for: WB, IHC-P, ICC/IF, FC expriments in human background without labeling.

HY-P80619

	c-Kit Antibody KIT; SCFR; mast/stem cell growth factor receptor Kit; SCFR; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD antigen CD117	WB, IHC-P	Human
	c-Kit Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 110 kDa, targeting to c-Kit. It can be used for WB,IHC-P assays with tag free, in the background of Human.

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Cat. No.	Product Name		Classification

HY-Y0320

Dimethyl sulfoxide 130+ Cited Publications DMSO		Solvents
Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties . MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition).

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