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Results for "

metal

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (2) Akt (4) Amino Acid Derivatives (2) Amyloid-β (8) Antibiotic (7) Apoptosis (14) Autophagy (5) Bacterial (19) Beta-lactamase (2) Biochemical Assay Reagents (107) Cholinesterase (ChE) (8) CMV (1) COMT (1) Cuproptosis (3) DNA/RNA Synthesis (1) Drug Metabolite (2) EGFR (1) Endogenous Metabolite (14) Ferroptosis (1) Fluorescent Dye (22) Fungal (2) GABA Receptor (1) GSK-3 (1) HDAC (3) HIF/HIF Prolyl-Hydroxylase (5) HIV (3) Isotope-Labeled Compounds (8) Liposome (1) Mitochondrial Metabolism (3) MMP (3) Monoamine Oxidase (5) NOD-like Receptor (NLR) (1) Orthopoxvirus (1) Parasite (1) PSMA (1) Radionuclide-Drug Conjugates (RDCs) (8) Reactive Oxygen Species (11) Reverse Transcriptase (1) SOD (7) Tau Protein (1) Topoisomerase (1) Xanthine Oxidase (3)
By Research Areas:	Cancer (49) Cardiovascular Disease (10) Infection (25) Inflammation/Immunology (22) Metabolic Disease (25) Neurological Disease (36)
Click Chemistry:	Azide (3) Tetrazine (1) Alkynes (3)
Oligonucleotides:	Antioxidants (1) Thickeners (1) Pegylated Lipids (1) Disintegrants (2) Suspending Agents (1) Emulsifiers (4) Phospholipids (1) Chelating Agents (2) pH Modifiers (1)

290

Inhibitors & Agonists

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Isotope-Labeled Compounds

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Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-136941

Antioxidant 1024 MD 1024	Others	Others
Antioxidant 1024 (MD 1024) is an antioxidant agent and metal deactivator .

HY-W012683

Iminodiacetic acid	Others	Cancer
Iminodiacetic acid (IDA) is a chelating agent that strongly binds transition metals . Iminodiacetic acid can be used for removal of toxic metal ions from water . Iminodiacetic acid can serve as a biomarker to potentially predict the severity of ARDS (acute respiratory distress syndrome) .

HY-B1335

Pentetic acid Diethylenetriaminepentaacetic acid; DTPA	Fluorescent Dye	Others
Pentetic acid (Diethylenetriaminepentaacetic acid) is an orally active compound with biodegradability used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater. Pentetic acid can form strong metal complexes, which prevents metal ions from catalysing the decomposition of peroxygen chemicals, especially hydrogen peroxide .

HY-16739

Emeramide NBMI; BDTH2	Cuproptosis Reactive Oxygen Species	Inflammation/Immunology Cancer
Emeramide is a thiol-redox antioxidant and heavy metal chelator .

HY-D0261

Tiron	Biochemical Assay Reagents Apoptosis	Metabolic Disease Inflammation/Immunology Cancer
Tiron is a non-toxic chelator of a variety of metals. Tiron is cell permeable analog of vitamin E and function as hydroxyl radical and superoxide scavenger. Tiron is an orally active antioxidant. Tiron can be used to alleviate acute metal overload in animals .

HY-144659

Metallo-β-lactamase-IN-5	Beta-lactamase Apoptosis Bacterial	Infection
Metallo-β-lactamase-IN-5 (compound 5c) is a potent metallo-β-lactamases (MBL) inhibitor. Metallo-β-lactamase-IN-5 shows inhibitory activity against MBLs NDM-1 and VIM-1. Metallo-β-lactamase-IN-5 inhibits HUVECs with an IC₅₀ of 45 μg/mL. Metallo-β-lactamase-IN-5 plus Imipenem exhibits synergistic antimicrobial activity .

HY-161094

Metallo-β-lactamase-IN-12	Beta-lactamase Bacterial	Infection
Metallo-β-lactamase-IN-12 is a dual inhibitor of metal β-lactamases (MβLs (NDM-1, IMP-1)) and serine β-lactamases (SβLs (OXA-48, KPC-2)), with IC₅₀ values of 0.64 μM, 1.32 μM, 1.01 μM, and 0.57 μM, respectively. Metallo-β-lactamase-IN-12 has antibacterial activity .

HY-121514

Talopeptin	Others	Others
Talopeptin is a metal protease inhibitor that can be produced by the streptomyces MK-23 .

HY-128370

Calcium trinatrium diethylenetriaminepentaacetic acid hydrate Ca-DTPA trisodium salt hydrate	CMV	Infection
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication). Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate is a nontoxic inhibitor of CMV replication .

HY-D1641

5,5'-Dimethyl BAPTA tetrapotassium	Fluorescent Dye	Others
5,5'-Dimethyl BAPTA tetrapotassium is a water-soluble, extracellular membrane metal chelator with relative selectivity for calcium ions .

HY-W175580

Phenylfluorone Fluorone black	Biochemical Assay Reagents	Others
Phenylfluorone (Fluorone black) can be used for photometric determination of some heavy metals, such as Germanium and Tin .

HY-W087043

N-Allylaniline N-phenylallylamine; N-Allyl-N-phenylamine	Others	Others
N-Allylaniline (N-phenylallylamine) is an aromatic amine that acts as a metal complex .

HY-Y0102

Thiosalicylic acid 2-Mercaptobenzoic acid	Biochemical Assay Reagents	Others
Thiosalicylic acid (2-Mercaptobenzoic acid) is a stabilizer that can be used in the synthesis of metal nanoparticles. Thiosalicylic acid is a biomaterial or organic compound that can be used in life science research .

HY-D1746

EDTA-AM EDTA acetoxymethyl ester; Ethylenediaminetetraacetic acid acetoxymethyl ester	Biochemical Assay Reagents	Others
EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) is the membrane-permeant form of the metal chelator EDTA (HY-Y0682). Live cells passively load EDTA-AM by incubating with EDTA-AM. Once internalized, cytoplasmic esterase decomposes AM esters, releasing the active ligand EDTA, which isolates metal ions within the cell. EDTA-AM induces an arrest of mitotic progression and chromosome decondensation .

HY-106671

Spirogermanium NSC 192965	Others	Others
Spirogermanium is a heavy metal compound that replaces germanium with azspirane ring structure and has anticancer activity. Spirogermanium could be used in lymphatic and breast cancer research .

HY-B1335R

Pentetic acid (Standard)	Fluorescent Dye	Others
Pentetic acid (Standard) is the analytical standard of Pentetic acid. This product is intended for research and analytical applications. Pentetic acid is a compound used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater .

HY-W151206

Hydroxy naphthol blue disodium	Fluorescent Dye	Others
Hydroxy naphthol blue disodium, an azo dye, is a metal indicator for calcium and a colorimetric reagent for alkaline earth metal ions ( λmax = 650 nm). In the pH range between 12 and 13, the solution of the indicator is reddish pink in the presence of calcium ion and to deep blue in the presence of disodium EDTA .

HY-137296

Lumogallion	Fluorescent Dye	Others
Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm .

HY-147962

AChE/HDAC-IN-1	Cholinesterase (ChE) HDAC	Neurological Disease
COX-2-IN-23 (compound A10) is a potent both AChE and HDAC inhibitor with IC₅₀ values of 0.12 and 0.23 nM. COX-2-IN-23 exhibits antioxidant activity and metal chelating properties. COX-2-IN-23 can be used in alzheimer's disease research .

HY-Y0032

Thiosemicarbazide	Orthopoxvirus	Infection Others Cancer
Thiosemicarbazide is a vitamin B6 antagonist with anti-acne activity. Thiosemicarbazide is also a well-known source in the synthesis of heterocycles, and its derivatives have potential anticancer activity. Thiosemicarbazide (TSC: HL1) reacts with metal salts, urea (U), to prepare Co(II) and Cu(I) metal complexes. Thiosemicarbazide is also used in the fields of media communications and optical storage, and in the spectrophotometric detection of metals .

HY-122507

Septamycin A 28695A; Antibiotic A 28695A	Antibiotic	Infection
Septamycin (A 28695A) is a metal complexing polyether antibiotic. Septamycin is produced by a strain of Streptomyces hygroscopicus NRRL 5678. Septamycin has anticoccidial activity .

HY-149820

MAO-B-IN-22	Monoamine Oxidase	Neurological Disease
MAO-B-IN-22 (compound 6h) is a potent MAO-B inhibitor with an IC₅₀ of 0.014 μM. MAO-B-IN-22 has high antioxidant activity, good metal chelating ability, proper BBB permeability and significant neuroprotective effect .

HY-W076836

4-Aminobenzaldehyde p-aminobenzaldehyde	Biochemical Assay Reagents	Others
4-Aminobenzaldehyde (p-aminobenzaldehyde) is a useful synthetic reagent and monomer that can be used to synthesize monoazo dyes and photocurable ion exchange resins. 4-Aminobenzaldehyde is also a corrosion inhibitor of metals .

HY-126302

DMT1 blocker 2 2 Publications Verification	Others	Metabolic Disease
DMT1 blocker 2 is a direct inhibitor of divalent metal transporter 1 (DMT1), with an IC₅₀ of 0.83 μM. DMT1 blocker 2 can block iron uptake by enterocytes in vivo .

HY-116454

GSK5750	Reverse Transcriptase HIV	Infection
GSK5750 is a specific and potent HIV-1 reverse transcriptase ribonuclease H inhibitor with an IC₅₀ value of 0.33 μM. GSK5750 is bound at the RNase H active site through a metalion chelation mechanism .

HY-N4084

Thonningianin A	Apoptosis	Cancer
Thonningianin A, an ellagitannin, is isolated from the methanolic extract of the African medicinal herb, Thonningia sanguinea. The antioxidant properties of Th A involve radical scavenging, anti-superoxide formation and metal chelation. Anti-cancer activities .

HY-W013205

Bis(4-nitrophenyl) phosphate	Biochemical Assay Reagents	Others
Bis(4-nitrophenyl) phosphate is a catalyst for metal micelles and can catalyze the hydrolysis of (4-nitrophenyl) phosphate. Bis(4-nitrophenyl) phosphate is also an effective catalyst for ring-opening polymerization (ROP), which can achieve controlled polymerization of β-butyrolactone (β-BL) ring-opening and can be used to prepare diembedded polymers without quenching. segment copolymer .

HY-162402

NLRP3-IN-33	Reactive Oxygen Species Cholinesterase (ChE)	Cancer
NLRP3-IN-33 (Compound 12o) is a blood-brain barrier permeable inhibitor of AChE and BChE, with IC₅₀ values of 1.02 μM and 7.03 μM against hAChE and hBChE respectively. NLRP3-IN-33 possesses antioxidant, anti-inflammatory, and metal chelating activities, making it a potential candidate for research in Alzheimer's disease (AD) .

HY-156403

AuM1Phe	Topoisomerase	Cancer
AuM1Phe, an N-Heterocyclic carbene (NHC) metal complexe, blocks the human topoisomerase I activity and actin polymerization reaction. AuM1Phe affects the growth of MDA-MB-231 breast cancer cells, with an IC₅₀ value of 1.2 μM .

HY-W013205R

Bis(4-nitrophenyl) phosphate (Standard)	Biochemical Assay Reagents	Others
Bis(4-nitrophenyl) phosphate (Standard) is the analytical standard of Bis(4-nitrophenyl) phosphate. This product is intended for research and analytical applications. Bis(4-nitrophenyl) phosphate is a catalyst for metal micelles and can catalyze the hydrolysis of (4-nitrophenyl) phosphate. Bis(4-nitrophenyl) phosphate is also an effective catalyst for ring-opening polymerization (ROP), which can achieve controlled polymerization of β-butyrolactone (β-BL) ring-opening and can be used to prepare diembedded polymers without quenching. segment copolymer .

HY-W115738

PAR	Biochemical Assay Reagents	Others
PAR is an azo dye widely used as a colorimetric reagent for metal ions. PAR forms stable chelates with different metal ions. PAR can also complex with heavy metal ions in polar organic solvent like ethanol .

HY-W134020

Semixylenol orange Semixylenol orange	Biochemical Assay Reagents	Others
Semixylenol orange is a metallochromic indicator that can complex with various metal ions and is used for the testing and analysis of metal ions such as zinc and zirconium .

HY-W129975

Boric anhydride,99.98% trace metals basis Boron trioxide,99.98% trace metals basis	Biochemical Assay Reagents
Boric anhydride,99.98% trace metals basis (Boron trioxide,99.98% trace metals basis) is a kind of biochemical reagent.

HY-126823

Phen Green SK diacetate (5/6-mixture) 5 Publications Verification PGSK diacetate (5/6-mixture)	Fluorescent Dye	Others
Phen green SK (PGSK) diacetate is a fluorescent heavy metal indicator that reacts with a variety of metal ions, including Fe2+, Cd2+, Co2+, Ni2+, Zn2+. PGSK diacetate displays excitation/emission maxima of 507/532 nm, respectively, and fluorescence is quenched upon interaction with metal ions

HY-162760

COMT-IN-1	COMT Monoamine Oxidase	Neurological Disease
COMT-IN-1 (compound C12), a nitrophenolic analogue, is an orally active dopamine metabolic enzyme catechol-O-methyltransferase (COMT) inhibitor with IC₅₀s of 0.37 μM, 95.58 μM and 58.82 μM for COMT, MAO-A and MAO-B, respectively. COMT-IN-1 exhibits chelation with a variety of metal ions. COMT-IN-1 exhibits good BBB permeability. COMT-IN-1 improves dopamine levels and ameliorates MPTP (HY-15608)-induced Parkinson's disease (PD) symptoms in mice .

HY-Y0449C

Ammonium thiocyanate, 99.99% trace metals basis Ammonium rhodanide, 99.99% trace metals basis	Biochemical Assay Reagents	Others
Ammonium thiocyanate, 99.99% trace metals basis is widely used in titration methods to determine the concentrations of various metal ions (especially iron and silver) by forming distinctly different complexes.

HY-17624

Framycetin Neomycin B; Fradiomycin B	Bacterial Antibiotic	Infection
Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a K_i of 35 μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a K_i of 13.5 μM. Framycetin, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections .

HY-W088011B

Sodium glycolate, 98% Sodium hydroxyacetate, 98%	Biochemical Assay Reagents	Others
Sodium glycolate, 98% is a metal chelating agent.

HY-17624A

Framycetin sulfate Neomycin B sulfate; Fradiomycin B sulfate	Antibiotic Bacterial	Infection
Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a K_i of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a K_i of 13.5 μM. Framycetin sulfate, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections .

HY-B1817A

Zinc acetate, 99.99% trace metals basis Zinc(II) acetate, 99.99% trace metals basis	Biochemical Assay Reagents	Others
Zinc acetate, 99.99% trace metals basis (Zinc(II) acetate, 99.99% trace metals basis) can be used as an alternative staining agent in SDS electrophoresis and can also affect the permeability of biological membranes.

HY-W105699

EDTA tetrasodium tetrahydrate Ethylenediaminetetraacetic acid tetrasodium tetrahydrate	Others	Others
EDTA tetrasodium tetrahydrate is a metal chelator (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. EDTA tetrasodium tetrahydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. EDTA tetrasodium tetrahydrate can also decrease the formation of disulfide bonds .

HY-W131302

Ethylenediaminediacetic acid N,N-Ethylenediglycine	Others	Cancer
Ethylenediaminediacetic acid (N,N-Ethylenediglycine) is an important ligand that enhances the antiproliferative activity of metal complexes. The complexes formed by ethylenediacetic acid and metal ions exhibited significant antiproliferative properties in MCF-7 cancer cell line. The metal complexes of ethylenediacetic acid were able to interact with DNA and were studied by CD and EPR spectroscopy techniques. Ethylenediaminediacetic acid and its metal complexes were able to induce cell cycle arrest at the G(0)/G(1) phase. The crystal structure analysis of ethylenediacetic acid provided important structural information for understanding its biological activity .

HY-149883

IZS-L	Others	Others
IZS-L is a amino acid-derived corrosion inhibitor. IZS-L exhibits corrosion inhibition performance for metal at longer immersion. IZSs, the series of corrosion inhibitors, inhibit mild steel corrosion through the formation of an inhibitor film on the metal surface .

HY-121858

Nicotianamine	Others	Others
Nicotianamine can be isolated from the leaves of Nicotiana Tabacum L.. Nicotianamine is a key biosynthetic precursor of phytosiderophores. Nicotianamine is an iron chelating agent and can promote the transport of iron. Nicotianamine is vital in metal nutrition and metal homeostasis of flowering plants .

HY-Y0537K

Potassium chloride, ACS, 99.0%	Biochemical Assay Reagents	Others
Potassium chloride, ACS, 99.0% is a metal halide salt composed of potassium and chlorine .

HY-Y0682S

EDTA-d12 Ethylenediaminetetraacetic acid-d₁₂	Isotope-Labeled Compounds	Neurological Disease
EDTA-d₁₂ is the deuterium labeled Ethylenediaminetetraacetic acid[1]. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds[2][3][4].

HY-164569

NH2 DOTA-GA	Radionuclide-Drug Conjugates (RDCs)	Cancer
NH2 DOTA-GA is a DOTA-based metal chelator that can be used to prepare radionuclide drug conjugates (RDCs) whose carboxylic acid groups can complex metal ions. For example, NH2 DOTA-GA complexes Gd(III) ions.

HY-Y0682S1

Ethylenediaminetetraacetic acid-d16 EDTA-d₁₆	Isotope-Labeled Compounds	Neurological Disease
Ethylenediaminetetraacetic acid-d₁₆ is the deuterium labeled Ethylenediaminetetraacetic acid[1]. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds[2][3][4].

HY-W036410

Aminopropyltrimethoxysilane 3-Aminopropyltrimethoxysilane	Biochemical Assay Reagents	Others
Aminopropyltrimethoxysilane (3-Aminopropyltrimethoxysilane) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-W011696

Oleylamine, 80-90% cis-1-Amino-9-octadecene, 80-90%	Biochemical Assay Reagents	Others
Oleylamine, 80-90% (cis-1-Amino-9-octadecene, 80-90%) is a long-chain primary alkylamine, which can be used in nanoparticle synthesis as a solvent, surfactant, and reducing agent. Oleylamine, 80-90% forms metastable complexes with metal ions, which can be controllably decomposed to produce nanoparticles. Oleylamine, 80-90% can control the morphology of nanoparticle, prevent the nanoparticle aggregation, and reduce metal precursors to metal nanoparticles .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W012683

Iminodiacetic acid	Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	Others
Iminodiacetic acid (IDA) is a chelating agent that strongly binds transition metals . Iminodiacetic acid can be used for removal of toxic metal ions from water . Iminodiacetic acid can serve as a biomarker to potentially predict the severity of ARDS (acute respiratory distress syndrome) .

HY-N4084

Thonningianin A	Structural Classification Classification of Application Fields Thonningia sanguinea Phenols Polyphenols Plants Disease Research Fields Balanophoraceae Cancer	Apoptosis
Thonningianin A, an ellagitannin, is isolated from the methanolic extract of the African medicinal herb, Thonningia sanguinea. The antioxidant properties of Th A involve radical scavenging, anti-superoxide formation and metal chelation. Anti-cancer activities .

HY-Y0682

Ethylenediaminetetraacetic acid 5+ Cited Publications EDTA	Classification of Application Fields Disease Research Fields Cancer	Biochemical Assay Reagents Bacterial SOD
Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .

HY-B1009

Ethylenediaminetetraacetic acid trisodium salt 5+ Cited Publications EDTA trisodium salt; Trisodium EDTA	Classification of Application Fields Disease Research Fields Cancer	Ferroptosis Bacterial SOD
Ethylenediaminetetraacetic acid trisodium salt (EDTA trisodium salt; Trisodium EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid trisodium salt has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid trisodium salt decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid trisodium salt can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .

HY-I0301

D-(+)-Glucono-1,5-lactone Gluconic acid lactone	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite Reactive Oxygen Species
D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.

HY-W015788

1-Phenylethane-1,2-diol Styrene Glycol	Structural Classification Natural Products Microorganisms Classification of Application Fields Other Diseases Disease Research Fields	Others
1-Phenylethane-1,2-diol is a typical benzyl diol compound. 1-Phenylethane-1,2-diol can be oxidized to hydroxyl ketone (2-hydroxy-1-phenylethan-1-one) selectively with variety of catalysts, including organocatalysts, metal complexes, non-noble metal oxides, bimetallics .

HY-W127329

12-Hydroxystearic acid	Microorganisms Source classification	Others
12-Hydroxystearic acid is a structurally simple and cost-effective low molecular weight organogelator, and its metal salts and derivatives find roles in many important applications .

HY-B0373

Tiopronin	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Others
Tiopronin is a diffusible antioxidant, an antidote to heavy metal poisoning and a radioprotective agent. Tiopronin can control the rate of cystine precipitation and excretion and has the potential for cystinuria, rheumatoid arthritis and hepatic disorders .

HY-121858

Nicotianamine	Structural Classification Nicotiana tabacum L. Ketones, Aldehydes, Acids Source classification Solanaceae Plants	Others
Nicotianamine can be isolated from the leaves of Nicotiana Tabacum L.. Nicotianamine is a key biosynthetic precursor of phytosiderophores. Nicotianamine is an iron chelating agent and can promote the transport of iron. Nicotianamine is vital in metal nutrition and metal homeostasis of flowering plants .

HY-119635

Albicanol	Structural Classification Natural Products Dryopteridaceae Dryopteris fragrans (L.) Schott Source classification Plants	Others
Albicanol is a sesquiterpenoid with potent antioxidant and antagonistic activities against heavy metal toxicity. Albicanol shows cytotoxicity. Albicanol suppress profenofos (HY-B0832) induced genotoxicity in grass carp hepatocytes .

HY-Y1310

Sodium alginate	Classification of Application Fields Disease Research Fields Cancer	Biochemical Assay Reagents
Sodium alginate is the sodium salt of alginic acid. Sodium alginate can be extracted and purified from brown seaweed Laminaria japonica. Sodium alginate can be used in food additives and pharmaceuticals, adsorb heavy metal ions, and has mucosal-protective and hemostatic effects .

HY-N0373

Licochalcone B 5 Publications Verification	Structural Classification Chalcones Flavonoids Leguminosae Source classification Plants Glycyrrhiza uralensis Fisch.	Amyloid-β Apoptosis NOD-like Receptor (NLR)
Licochalcone B is an extract from the root of Glycyrrhiza uralensis. Licochalcone B inhibits amyloid β (₄₂) self-aggregation (IC₅₀=2.16 μM) and disaggregate pre-formed Aβ₄₂ fibrils, reduce metal-induced Aβ₄₂ aggregation through chelating metal ionsLicochalcone B inhibits phosphorylation of NF-κB p65 in LPS signaling pathway. Licochalcone B inhibits growth and induces apoptosis of NSCLC cells. Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction .

HY-N0513

Loganic acid	Cardiovascular Disease Structural Classification Iridoids Cornaceae Classification of Application Fields Cornus officinalis Sieb. et Zucc. Terpenoids Source classification Plants Disease Research Fields	Others
Loganic acid is an iridoid isolated from cornelian cherry fruits. Loganic acid can modulate diet-induced atherosclerosis and redox status. Loganic acid has strong free radical scavenging activity and remarkable cyto-protective effect against heavy metal mediated toxicity .

HY-N9413

γ-Glutamyl-S-allylcysteine L-γ-Glutamyl-(S)-Allyl-Cysteine	Liliaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Allium sativum Linn. Plants Disease Research Fields	Others
γ-Glutamyl-S-allylcysteine (L-γ-Glutamyl-(S)-Allyl-Cysteine) is a naturally occurring organosulfur compound found in garlic. γ-Glutamyl-S-allylcysteine has antiglycative effect and shows radical-scavenging and metal-chelating capacities .

HY-N0848

Epibrassinolide Maximum Cited Publications 13 Publications Verification 24-Epibrassinolide; B1105; BP55	Structural Classification Natural Products Classification of Application Fields Source classification Plants Biological Pesticide Research Agricultural Research Brassinolide Phytohormone Brassicaceae Brassica campestris L. Disease Research Fields Cancer	Apoptosis
Epibrassinolide (24-Epibrassinolide) is a ubiquitously occurring plant growth hormone which shows great potential to alleviate heavy metals and pesticide stress in plants . Epibrassinolide is a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth .

HY-N0928

Mimosine	Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Inflammation/Immunology Disease Research Fields	Apoptosis
Mimosine, a tyrosine analog , can act as an antioxidant by its potent iron-binding activity . Mimosine is a known chelator of Fe(III) . Mimosine induces apoptosis through metal ion chelation, mitochondrial activation and ROS production in human leukemic cells . Anti-cancer, antiinflammation.

HY-W127329R

12-Hydroxystearic acid (Standard)	Microorganisms Source classification	Others
12-Hydroxystearic acid (Standard) is the analytical standard of 12-Hydroxystearic acid. This product is intended for research and analytical applications. 12-Hydroxystearic acid is a structurally simple and cost-effective low molecular weight organogelator, and its metal salts and derivatives find roles in many important applications .

HY-I0301R

D-(+)-Glucono-1,5-lactone (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite Saccharides	Endogenous Metabolite Reactive Oxygen Species
D-(+)-Glucono-1,5-lactone (Standard) is the analytical standard of D-(+)-Glucono-1,5-lactone. This product is intended for research and analytical applications. D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.

HY-Y1310R

Sodium alginate (Standard)	Structural Classification Natural Products Haplopteris anguste-elongata (Hayata) E. H. Crane other families Plants	Biochemical Assay Reagents
Sodium alginate (Standard) is the analytical standard of Sodium alginate. This product is intended for research and analytical applications. Sodium alginate is the sodium salt of alginic acid. Sodium alginate can be extracted and purified from brown seaweed Laminaria japonica. Sodium alginate can be used in food additives and pharmaceuticals, adsorb heavy metal ions, and has mucosal-protective and hemostatic effects .

HY-N7648

Atherosperminine Atherospermine	Infection Alkaloids Classification of Application Fields Source classification Fissistigma glaucescens Plants Annonaceae Disease Research Fields	Parasite
Atherosperminine（Atherospermine）is a nature occurring alkaloid, has antiplasmodial activities in vitro, with an IC₅₀ of 5.80 μM. Atherosperminine is a good reductant with the ability to chelate metals. Atherosperminine has scavenging activity towards the free radical DPPH, with an IC₅₀ of 29.56 µg/mL. Atherosperminine exerts a non-specific relaxant effect on the trachealis .

HY-N0814B

Phytic acid hexasodium Inositol hexaphosphate hexasodium; SNF472	Structural Classification other families Ketones, Aldehydes, Acids Source classification Plants	Endogenous Metabolite
Phytic acid (Inositol hexaphosphate) hexasodium is a phosphorus storage compound of seeds and cereal grains. Phytic acid hexasodium has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid hexasodium inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.

HY-Y1024

Pyridine-2,6-dicarboxylic acid 2,6-Pyridinedicarboxylic acid	Microorganisms Source classification	Biochemical Assay Reagents
Pyridine-2,6-dicarboxylic acid is a dicarboxylic acid containing a pyridine ring with unique chemical properties that make it an important ingredient in a variety of industrial processes. Pyridine-2,6-dicarboxylic acid is commonly used as a ligand for metal ions, a building block in the synthesis of pharmaceuticals and organic compounds, and a precursor in the production of pigments and dyes.

HY-N0513R

Loganic acid (Standard)	Structural Classification Iridoids Cornaceae Cornus officinalis Sieb. et Zucc. Terpenoids Source classification Plants	Others
Loganic acid (Standard) is the analytical standard of Loganic acid. This product is intended for research and analytical applications. Loganic acid is an iridoid isolated from cornelian cherry fruits. Loganic acid can modulate diet-induced atherosclerosis and redox status. Loganic acid has strong free radical scavenging activity and remarkable cyto-protective effect against heavy metal mediated toxicity .

HY-B0300

Penicillamine 2 Publications Verification D-(-)-Penicillamine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Inflammation/Immunology Disease Research Fields	Cuproptosis Drug Metabolite
Penicillamine (D-(-)-Penicillamine) is a penicillin metabolic degradation product, can be used as a heavy metal chelator. Penicillamine reduces free copper and reduces oxidative stress. Penicillamine has effect of seizures through nitric oxide/NMDA pathways. Penicillamine is a potential immune modulator. Penicillamine can be used for the research of Wilson disease, rheumatoid arthritis, and cystinuria .

HY-N0814

Phytic acid 1 Publications Verification Inositol hexaphosphate; SNF472 free acid	Structural Classification Neurological Disease Classification of Application Fields Food Preservation Research Source classification Plants Endogenous metabolite Agricultural Research Microorganisms other families Ketones, Aldehydes, Acids Inflammation/Immunology Disease Research Fields	Xanthine Oxidase Endogenous Metabolite
Phytic acid (Inositol hexaphosphate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects .

HY-N0814A

Phytic acid dodecasodium hydrate 1 Publications Verification Inositol hexaphosphate dodecasodium hydrate; SNF472 dodecasodium hydrate	Structural Classification other families Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite	Xanthine Oxidase Endogenous Metabolite
Phytic acid (Inositol hexaphosphate) dodecasodium hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects .

HY-B0300R

Penicillamine (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Cuproptosis Drug Metabolite
Penicillamine (Standard) is the analytical standard of Penicillamine. This product is intended for research and analytical applications. Penicillamine (D-(-)-Penicillamine) is a penicillin metabolic degradation product, can be used as a heavy metal chelator. Penicillamine reduces free copper and reduces oxidative stress. Penicillamine has effect of seizures through nitric oxide/NMDA pathways. Penicillamine is a potential immune modulator. Penicillamine can be used for the research of Wilson disease, rheumatoid arthritis, and cystinuria .

HY-N0814R

Phytic acid (Standard)	Structural Classification Microorganisms other families Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite	Xanthine Oxidase Endogenous Metabolite
Phytic acid (Standard) is the analytical standard of Phytic acid. This product is intended for research and analytical applications. Phytic acid (Inositol hexaphosphate) is a phosphorus storage compound of seeds and cereal grains. Phytic acid is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects .

HY-N1964

Gibberellic acid 1 Publications Verification Gibberellin A3	Structural Classification Microorganisms Classification of Application Fields Gibberellins Rutaceae Other Diseases Plants Phytohormone Disease Research Fields Citrus reticulata Blanco Agricultural Research	Others
Gibberellic Acid is named after the fungus Gibberella fujikuroi. Gibberellic Acid regulates processes in plant development and growth, including seed development and germination, stem and root growth, cell division, and flowering time. Gibberellic Acid also improves plant response to growth stress caused by various environmental stresses, such as cold stress, drought stress, heavy metal stress, etc. Gibberellic Acid also causes increased lipid peroxidation and fluctuations in the antioxidant defense system in rats .

HY-N2362

DL-Alanine DL-2-Aminopropionic acid	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-W013494R

L-Carnosine (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite	Endogenous Metabolite
L-Carnosine (Standard) is the analytical standard of L-Carnosine. This product is intended for research and analytical applications. L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging. In Vitro: L-Carnosine is a dipeptide of the amino acids beta-alanine and histidine and has the potential to suppress many of the biochemical changes that accompany aging . L-Carnosine also exhibits some antioxidant effects. The antioxidant mechanism of L-Carnosine is attributed to its chelating effect against metal ions, superoxide dismutase (SOD)-like activity, and ROS and free radicals scavenging ability .

HY-129200

Aspergillomarasmine A	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Others
Aspergillomarasmine A is a natural aminopolycarboxylic acid with potent inhibitory activity against class B metallo-β-lactamases (MBLs). Aspergillomarasmine A inactivates MBLs by removing a catalytic Zn2+ cofactor. Aspergillomarasmine A acts as a selective Zn2+ scavenger, promoting the dissociation of the metal cofactor, thereby indirectly inactivating NDM-1. Aspergillomarasmine A causes the loss of Zn2+ ions from the low-affinity binding site of NDM-1. The action of Aspergillomarasmine A results in the rapid degradation of Zn2+-deficient NDM-1, thereby enhancing its potency as a β-lactam enhancer. The mechanism of Aspergillomarasmine A has broad applicability among different Zn2+ chelators .

Cat. No.	Product Name	Chemical Structure

HY-Y0682S

EDTA-d12

EDTA-d₁₂ is the deuterium labeled Ethylenediaminetetraacetic acid[1]. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds[2][3][4].

HY-N2362S2

DL-Alanine-d3

DL-Alanine-d₃ is the deuterium labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].

HY-N2362S

DL-Alanine-13C-1

DL-Alanine- ¹³C-1 is the ¹³C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].

HY-N2362S1

DL-Alanine-13C-3

DL-Alanine- ¹³C-3 is the ¹³C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].

HY-Y0682S1

Ethylenediaminetetraacetic acid-d16

Ethylenediaminetetraacetic acid-d₁₆ is the deuterium labeled Ethylenediaminetetraacetic acid[1]. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds[2][3][4].

HY-W030778S

Nitrilotriacetic acid-d9
Nitrilotriacetic acid-d₉ is the deuterium labeled Nitrilotriacetic acid[1]. Nitrilotriacetic acid is an aminotricarboxylic acid. Nitrilotriacetic acid can be used as a chelating agent, forming coordination compounds with metal ions[2].

HY-B0373S1

Tiopronin-d3
Tiopronin-d₃ is the deuterium labeled Tiopronin. Tiopronin is a diffusible antioxidant, an antidote to heavy metal poisoning and a radioprotective agent. Tiopronin can control the rate of cystine precipitation and excretion and has the potential for cystinuria, rheumatoid arthritis and hepatic disorders[1][2].

HY-W010179S1

2-Methoxynaphthalene-d2
2-Methoxynaphthalene-d2 is the deuterium labeled 2-Methoxynaphthalene (HY-W101130). 2-Methoxynaphthalene can be used to investigate the catalytic benefits of delamination, as well as to study alkali metal-mediated manganization (AMMMn) reactions .

HY-I0301S

D-(+)-Glucono-1,5-lactone-1-13C
D-(+)-Glucono-1,5-lactone-1- ¹³C is the ¹³C labeled D-(+)-Glucono-1,5-lactone. D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activ[1][2].

HY-W004544S

o-Phenanthroline-d8
o-Phenanthroline-d₈ is the deuterium labeled o-Phenanthroline. o-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline (1,10-Phenanthroline) forms a red chelate with Fe2+ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) is also a MMP inhibitor[1][2].

HY-N2362S5

DL-Alanine-15N

DL-Alanine- ¹⁵N is the ¹⁵N labeled DL-Alanine[1]. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[2][3][4][5][6][7].

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