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CAM833 is a potent orthosteric inhibitor of the interaction between BRCA2 and RAD51 with a Kd of 366 nM against the ChimRAD51 protein. CAM833 also inhibits RAD51 oligomerization. CAM833 increases the progression of G2/M-arrested cells into apoptosis .
Arg-Arg-AMC acetate is the acetate salt form of Arg-Arg-AMC (HY-P4340). Arg-Arg-AMC acetate is a fluorescent substrate for cathepsin B and used in the cathepsin B activity assay .
Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) acetate is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg acetate is a substrate of EGF receptor protein kinase C and can be used to measure protein kinase C activity .
Beauverolide Ja, a cyclotetradepsipeptide, is a potent calmodulin (CaM) inhibitor with a Kd of 0.078 μM and a Ki of 0.39 μM for Ca 2+-CaM. Beauverolide Ja is a secondary metabolite of Isaria fumosorosea .
Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of protein kinase C from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of protein kinase C .
CAM2602 is an Aurora A-TPX2 interaction inhibitor that has a binding affinity of 19 nM to Aurora A. CAM2602 can inhibit the growth of pancreatic cancer cells. In solid tumor transplant models, CAM2602 can increase the proportion of PH3 positive cells while reducing the proportion of P-Thr288 Aurora A positive cells, thereby inhibiting tumor growth .
Arg-Arg-AMC is a highly selective substrate of Cathepsin B. Arg-Arg-AMC can be used to cathepsin B activity assay in cancer cells, while cathepsin B is assocaited with cell invasive and metastatic phenotype in numerous types of cancer .
c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] (Compound 9C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 25 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .
Boc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) is an inhibitor for chitinase. Cyclo(Arg-Pro) inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) inhibits the morphological change of Candida albicans from yeast form to filamentous form .
Z-Arg-Arg-βNA acetate is a sensitive dipeptide substrate of the protease Cathepsin B and resistant to proteases H and L. Z-Arg-Arg-βNA acetate can serve as an important tool for distinguishing non-Cathepsin B type proteins .
CaMKI (299-320) refers to a peptide consisting of residues 299-320 of Calcium/calmodulin-dependent protein kinase I (CaMKI). CaMKI (299-320), as a protein kinase, has a high affinity interaction with Ca 2+-CAM (Kd≤1 nM≤1 nM), which can phosphorylate specific substrate proteins, thereby regulating their activity. CaMKI (299-320) contains the CAM-binding domain and the self-inhibition domain, and CaMKI (299-320) can be used to study cell physiological processes, including cell proliferation, differentiation, and apoptosis .
Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor (GM-CSF) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death .
c[Arg-Arg-Arg-Arg-Dip-Dip-Dip] (Compound 8C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 12.5 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .
L1CAM Human Pre-designed siRNA Set A contains three designed siRNAs for L1CAM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Hippuryl-Arg (Bz-Gly-Arg) is a substrate used for fluorescence detection and is commonly used in biochemical studies, especially in studying enzyme activity. The phenylalanine portion of Hippuryl-Arg is connected by an aromatic side chain, which allows it to be detected under ultraviolet light. Hippuryl-Arg is used to detect enzymes that recognize and cut peptide bonds containing arginine .
FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO). FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL)-treated cells, PRL regulates CPD mRNA levels in cells .
Pyr-Arg-Thr-Lys-Arg-AMC is a AMC peptide. AMC is a decapeptide that is specifically hydrolyzed by proteases such as trypsin and thrombin. The AMC peptide can be used to determine the activity of protease and the potency of enzyme inhibitors .
Cyclo(Arg-dPro) is an inhibitor of chitinase. Cyclo(Arg-Pro) inhibits the cell separation of Saccharomyces cerevisiae but does not affect its growth. Cyclo(Arg-Pro) inhibits the transition of Candida albicans from yeast to filamentous morphology.
Pyr-Arg-Thr-Lys-Arg-AMC TFA is a AMC peptide. AMC is a decapeptide that is specifically hydrolyzed by proteases such as trypsin and thrombin. The AMC peptide can be used to determine the activity of protease and the potency of enzyme inhibitors .
N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat .
Boc-LRR-AMC (Boc-Leu-Arg-Arg-AMC) is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
Met-Arg-Phe-Ala is a peptide. Met-Arg-Phe-Ala also is a potent competitive inhibitor for enkephalin-generating endopeptidase (EGE). Met-Arg-Phe-Ala can be used for the research of neurological disease .
Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) TFA is a chitinase inhibitor. Cyclo(Arg-Pro) TFA inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) TFA inhibits the morphological change of Candida albicans from yeast form to filamentous form .
Bz-Ala-Arg is a dipeptide. Bz-Ala-Arg is also a spectrophotometric substrate (0.4 M pyridine formate, pH 4.25) of human pancreatic carboxypeptidase B and plasma carboxypeptidase N. Bz-Ala-Arg can be used to screen competitive inhibitors of these two enzymes .
PD 136450 (CAM 1189) is an antagonist for cholecystokinin 2 (CCK2). PD 136450 exhibits anti-secretory, anxiolytic and anti-ulcer activities, inhibits gastric acid secretion (IC50=1 mg/kg), and ameliorates the haemorrhagic lesions (IC50=4.7 mg/kg) in rats .
Eltrombopag- 13C4 (SB-497115- 13C4) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .
H-Arg-Phe-OH is an amphipathic peptide. H-Arg-Phe-OH has the ability to induce native-like protein aggregation. H-Arg-Phe-OH can induce aggregation of the neutral model protein yeast alcohol dehydrogenase (ADH) .
D-Val-Leu-Arg-pNA (acetate) is the acetate form of D-Pro-Phe-Arg-p-nitroanilide (pNa). D-Pro-Phe-Arg-p-nitroanilide (pNa) is the substrate for kallikrein and can be used to assay the activity of kallikrein .
Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes .
H-Phe-Arg-OH is a dipeptide containing phenylalanine and arginine. H-Phe-Arg-OH can be separated from Bradykinin (HY-P0206) through Angiotensin-converting enzyme (ACE, HY-P2983). H-Phe-Arg-OH can be used for metabolic research .
Bz-Ala-Arg TFA is a dipeptide. Bz-Ala-Arg TFA is also a spectrophotometric substrate (0.4 M pyridine formate, pH 4.25) of human pancreatic carboxypeptidase B and plasma carboxypeptidase N. Bz-Ala-Arg TFA can be used to screen competitive inhibitors of these two enzymes .
H-Arg-OtBu (dihydrochloride) is a membrane-targeting antimicrobial. H-Arg-OtBu (dihydrochloride) targets the negatively charged bacterial membrane via a combination of electrostatic and hydrophobic interactions. H-Arg-OtBu (dihydrochloride) can be used for bacterial infections diseases research .
Arg-Flipper 34 is one of the flipper probes which have been introduced as small molecule fluorophores to image membrane tension in living systems. Arg-Flipper 34 can be used to assess the mechanics of early endocytosis .
(Arg)9 (Nona-L-arginine) is a cell-penetrating peptide (CPP) made up of 9 arginine residues, which is an inhibitor of serine endoprotease Furin. (Arg)9 has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model .
Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .
Boc-L-Arg(Mtr)-OH (Boc-Arg(Mtr)-OH) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antithrombotic activity .
Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) TFA is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes .
Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor, and inhibits serine/threonine proteases. Dansyl-Glu-Gly-Arg-Chloromethylketone inhibits activated porcine factor IX .
Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity .
H-Gly-Arg-pNA hydrochloride (GR-pNA hydrochloride) is a colorimetric substrate for thrombin. H-Gly-Arg-pNA is preferentially bound by thrombin and cleaves the Gly-Arg (GR) peptide sequence, releasing p-nitroaniline (pNA) that can be detected colorimetrically at 405 nm. H-Gly-Arg-pNA hydrochloride is used as a fluorescent dye to measure thrombin activity .
Cho-Arg TFA is a steroid-based cationic lipid with an L-Arginine headgroup. Cho-Arg TFA shows a remarkably high optimized plasmid DNA transfection efficacy .
Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm) .
Boc-LRR-AMC TFA (Boc-Leu-Arg-Arg-AMC TFA) is the TFA salt form of Boc-LRR-AMC (HY-115391). Boc-LRR-AMC TFA is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
Arg-Flipper 34 is one of the flipper probes which have been introduced as small molecule fluorophores to image membrane tension in living systems. Arg-Flipper 34 can be used to assess the mechanics of early endocytosis .
H-Gly-Arg-pNA hydrochloride (GR-pNA hydrochloride) is a colorimetric substrate for thrombin. H-Gly-Arg-pNA is preferentially bound by thrombin and cleaves the Gly-Arg (GR) peptide sequence, releasing p-nitroaniline (pNA) that can be detected colorimetrically at 405 nm. H-Gly-Arg-pNA hydrochloride is used as a fluorescent dye to measure thrombin activity .
Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm) .
(Arg)9, FAM-labeled, a cell-penetrating peptide (CPP), is a nona-arginine (ARG) with FAM label. CPPs have emerged as powerful tools for delivering bioactive cargoes into the cytosol of intact cells .
Arg-Arg-AMC acetate is the acetate salt form of Arg-Arg-AMC (HY-P4340). Arg-Arg-AMC acetate is a fluorescent substrate for cathepsin B and used in the cathepsin B activity assay .
Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) acetate is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg acetate is a substrate of EGF receptor protein kinase C and can be used to measure protein kinase C activity .
Cys(Npys)-(Arg)9 is a cell penetrating peptide. Cys(Npys)-(Arg)9 is comprised of 9 D-Arginine residues and an activated cysteine residue C(Npys). Cys(Npys)-(Arg)9 can be used as a carrier peptide applicable in conjugation and cell permable studies .
Cys(NPys)-D{Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg}-NH2 is a cell-penetrating polypeptide composed of nine arginines and cysteines, used to carry therapeutic agent into the cell .
Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of protein kinase C from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of protein kinase C .
Arg-Arg-AMC is a highly selective substrate of Cathepsin B. Arg-Arg-AMC can be used to cathepsin B activity assay in cancer cells, while cathepsin B is assocaited with cell invasive and metastatic phenotype in numerous types of cancer .
c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] (Compound 9C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 25 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .
Boc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) is an inhibitor for chitinase. Cyclo(Arg-Pro) inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) inhibits the morphological change of Candida albicans from yeast form to filamentous form .
Bz-Nle-Lys-Arg-Arg-AMC can be used for protease activity assay. In 0.1mL Tris-HCl buffer (50 mM, pH 7.8), Bz-Nle-Lys-Arg-Arg-AMC was hydrolyzed, and the release rate of AMC was observed and calculated at λex/λem=380 nm/460 nm .
Z-Arg-Arg-βNA acetate is a sensitive dipeptide substrate of the protease Cathepsin B and resistant to proteases H and L. Z-Arg-Arg-βNA acetate can serve as an important tool for distinguishing non-Cathepsin B type proteins .
(Arg)9 biotin labeled is a cell-permeable peptide. (Arg)9 biotin labeled can be used for drug delivery. (Arg)9 biotin labeled can traverse the plasma membrane of eukaryotic cells .
CaMKI (299-320) refers to a peptide consisting of residues 299-320 of Calcium/calmodulin-dependent protein kinase I (CaMKI). CaMKI (299-320), as a protein kinase, has a high affinity interaction with Ca 2+-CAM (Kd≤1 nM≤1 nM), which can phosphorylate specific substrate proteins, thereby regulating their activity. CaMKI (299-320) contains the CAM-binding domain and the self-inhibition domain, and CaMKI (299-320) can be used to study cell physiological processes, including cell proliferation, differentiation, and apoptosis .
c[Arg-Arg-Arg-Arg-Dip-Dip-Dip] (Compound 8C) shows broad-spectrum activity against drug-resistant Gram-positive and Gram-negative bacteria, with MICs of 3.1, 3,1, 12.5, and 12.5 μg/mL for MRSA (ATCC BAA-1556), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27883), and E. coli (ATCC 25922), respectively .
Ala-Arg-Arg-Pro-Glu-Gly-Arg-Thr-Trp-Ala-Gln-Pro-Gly-Tyr is a peptide. Ala-Arg-Arg-Pro-Glu-Gly-Arg-Thr-Trp-Ala-Gln-Pro-Gly-Tyr can easily be formed with more than one positive charge .
Gly-Gly-Arg is a tripeptide, and a “pumping pheromone” released from the hatching eggs. Gly-Gly-Arg induces pleopod pumping activity, with the threshold concentration of 10 nM. Gly-Gly-Arg shows maximum percentage response of 58.3%. Gly-Gly-Arg act as pheromones and controlls larval release in subtidal crustaceans .
FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO). FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL)-treated cells, PRL regulates CPD mRNA levels in cells .
Pyr-Arg-Thr-Lys-Arg-AMC is a AMC peptide. AMC is a decapeptide that is specifically hydrolyzed by proteases such as trypsin and thrombin. The AMC peptide can be used to determine the activity of protease and the potency of enzyme inhibitors .
Pyr-Arg-Thr-Lys-Arg-AMC TFA is a AMC peptide. AMC is a decapeptide that is specifically hydrolyzed by proteases such as trypsin and thrombin. The AMC peptide can be used to determine the activity of protease and the potency of enzyme inhibitors .
N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat .
Boc-LRR-AMC (Boc-Leu-Arg-Arg-AMC) is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
Met-Arg-Phe-Ala is a peptide. Met-Arg-Phe-Ala also is a potent competitive inhibitor for enkephalin-generating endopeptidase (EGE). Met-Arg-Phe-Ala can be used for the research of neurological disease .
Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) TFA is a chitinase inhibitor. Cyclo(Arg-Pro) TFA inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) TFA inhibits the morphological change of Candida albicans from yeast form to filamentous form .
Bz-Ala-Arg is a dipeptide. Bz-Ala-Arg is also a spectrophotometric substrate (0.4 M pyridine formate, pH 4.25) of human pancreatic carboxypeptidase B and plasma carboxypeptidase N. Bz-Ala-Arg can be used to screen competitive inhibitors of these two enzymes .
H-Arg-Phe-OH is an amphipathic peptide. H-Arg-Phe-OH has the ability to induce native-like protein aggregation. H-Arg-Phe-OH can induce aggregation of the neutral model protein yeast alcohol dehydrogenase (ADH) .
D-Val-Leu-Arg-pNA (acetate) is the acetate form of D-Pro-Phe-Arg-p-nitroanilide (pNa). D-Pro-Phe-Arg-p-nitroanilide (pNa) is the substrate for kallikrein and can be used to assay the activity of kallikrein .
Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes .
H-Phe-Arg-OH is a dipeptide containing phenylalanine and arginine. H-Phe-Arg-OH can be separated from Bradykinin (HY-P0206) through Angiotensin-converting enzyme (ACE, HY-P2983). H-Phe-Arg-OH can be used for metabolic research .
Bz-Ala-Arg TFA is a dipeptide. Bz-Ala-Arg TFA is also a spectrophotometric substrate (0.4 M pyridine formate, pH 4.25) of human pancreatic carboxypeptidase B and plasma carboxypeptidase N. Bz-Ala-Arg TFA can be used to screen competitive inhibitors of these two enzymes .
(Arg)9 (Nona-L-arginine) is a cell-penetrating peptide (CPP) made up of 9 arginine residues, which is an inhibitor of serine endoprotease Furin. (Arg)9 has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model .
Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM -1s -1), and can be used for detection of proteinase 3 (PR3) activity .
Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) .
Boc-L-Arg(Mtr)-OH (Boc-Arg(Mtr)-OH) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antithrombotic activity .
Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) TFA is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes .
Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor, and inhibits serine/threonine proteases. Dansyl-Glu-Gly-Arg-Chloromethylketone inhibits activated porcine factor IX .
Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity .
[Leu144,Arg147]-PLP (139-151) is a mutant peptide fragment of myelin proteolipid protein (PLP), with the tryptophan and histidine at positions 144 and 147 respectively replaced by leucine and arginine. [Leu144,Arg147]-PLP (139-151) also serves as a T cell receptor (TCR) antagonist for encephalitogenic Th1 clones, blocking their activation in vitro. Furthermore, [Leu144,Arg147]-PLP (139-151) can inhibit the development of experimental autoimmune encephalomyelitis (EAE) .
Boc-LRR-AMC TFA (Boc-Leu-Arg-Arg-AMC TFA) is the TFA salt form of Boc-LRR-AMC (HY-115391). Boc-LRR-AMC TFA is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
Cys(Npys)-(D-Arg)9 is an amphipathic R9 cell penetrating peptide (CPP). Cys(Npys)-(D-Arg)9 has cytotoxicity for microspore cells with the amount higher than 1 nmol .
H-Gly-Pro-Arg-Pro-NH2 is a peptide that mimics the N-terminal Gly-Pro-Arg region in the a chain of fibrin protein. H-Gly-Pro-Arg-Pro-NH2 prevents fibrin polymerization .
Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor (GM-CSF) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death .
Beauverolide Ja, a cyclotetradepsipeptide, is a potent calmodulin (CaM) inhibitor with a Kd of 0.078 μM and a Ki of 0.39 μM for Ca 2+-CaM. Beauverolide Ja is a secondary metabolite of Isaria fumosorosea .
Calmodulin Protein, Human is a recombinant human Calmodulin expressed in E. coli. Calmodulin is a low molecular weight, acidic, calcium binding protein which mediates the Ca2+ regulation of a wide range of physiological processes throughout eukaryotic organisms.
The L1CAM protein is a neural cell adhesion molecule that plays a key role in cell adhesion dynamics and transmembrane signaling during brain development.It contributes to neuronal migration, axonal growth, fasciculation, and synaptogenesis.L1CAM Protein, Mouse (HEK293, His) is the recombinant mouse-derived L1CAM protein, expressed by HEK293 , with C-His labeled tag.
The CAMKK1 protein is a calcium/calmodulin-dependent kinase and a key player in calcium-triggered signaling cascades involved in various cellular processes. It phosphorylates multiple members of the CAMK1 family, including CAMK1, CAMK1D, CAMK1G, and CAMK4. CAMKK1 Protein, Human (Sf9) is the recombinant human-derived CAMKK1 protein, expressed by Sf9 insect cells , with tag free. The total length of CAMKK1 Protein, Human (Sf9) is 505 a.a., .
The CAMKK1 protein is a calcium/calmodulin-dependent kinase and a key player in calcium-triggered signaling cascades involved in various cellular processes. It phosphorylates multiple members of the CAMK1 family, including CAMK1, CAMK1D, CAMK1G, and CAMK4. CAMKK1 Protein, Human (Sf9, His) is the recombinant human-derived CAMKK1 protein, expressed by Sf9 insect cells , with N-6*His labeled tag. The total length of CAMKK1 Protein, Human (Sf9, His) is 505 a.a., .
The PNCK protein is a calcium/calmodulin-dependent protein kinase and a key component of the calcium-triggered signaling cascade. In vitro, PNCK exhibits the ability to phosphorylate CREB1 and SYN1/synapsin I, emphasizing its involvement in regulating cellular processes associated with these substrates. PNCK Protein, Human (Sf9, GST) is the recombinant human-derived PNCK protein, expressed by Sf9 insect cells , with GST tagged. The total length of PNCK Protein, Human (Sf9, GST) is 342 a.a., .
The PNCK protein is a calcium/calmodulin-dependent protein kinase and a key component of the calcium-triggered signaling cascade. In vitro, PNCK exhibits the ability to phosphorylate CREB1 and SYN1/synapsin I, emphasizing its involvement in regulating cellular processes associated with these substrates. PNCK Protein, Human (Sf9, His, GST) is the recombinant human-derived PNCK protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of PNCK Protein, Human (Sf9, His, GST) is 342 a.a., .
CAMKK1 Protein, Rat (F230G, sf9, GST) is the recombinant rat-derived CAMKK1, expressed by Sf9 insect cells , with GST labeled tag. The total length of CAMKK1 Protein, Rat (F230G, sf9, GST) is 505 a.a.,
CAMK1 delta Protein, Human (sf9, GST) is the recombinant human-derived CAMK1 delta, expressed by Sf9 insect cells , with GST labeled tag. The total length of CAMK1 delta Protein, Human (sf9, GST) is 384 a.a.,
VCAM-1/CD106 proteins expressed on endothelial cells critically regulate leukocyte adhesion through integrin interactions, initiating calcium channel activation and RAC1-mediated transendothelial migration during inflammation. VCAM-1/CD106 Protein, Human (Biotinylated, HEK293, hFc) is the recombinant human-derived VCAM-1/CD106 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of VCAM-1/CD106 Protein, Human (Biotinylated, HEK293, hFc) is 673 a.a., with molecular weight of ~101 kDa.
Arginase-2/ARG2 Protein, Human (His) expresses in E. coli with a His tag at the N-terminus. Arginase-2 (Arg2) acts as a fasting-induced hepatocyte factor that protects against hepatic and peripheral fat accumulation, hepatic inflammatory responses, and insulin and glucose intolerance in obese murine models.
The CALM2 protein is an important component of calcium signaling, controlling enzymes, ion channels, and aquaporins through calcium binding. CALM2 Protein, Human (His) is the recombinant human-derived CALM2 protein, expressed by E. coli , with N-His labeled tag. The total length of CALM2 Protein, Human (His) is 149 a.a., with molecular weight of ~19 kDa.
CAMKIV/CAMK4 protein phosphorylates transcriptional activators (CREB1, MEF2D, JUN, RORA) involved in immune response, inflammation, and memory consolidation.CAMKIV/CAMK4 regulate T cell selection, cytokine production, osteoclast/dendritic cell differentiation, and survival.CAMKIV/CAMK4 Protein, Rat (His) is the recombinant rat-derived CAMKIV/CAMK4 protein, expressed by E.coli , with N-6*His labeled tag.
Arginase-1 Protein, Human (C-His) expresses in E. coli with a His tag at the C-terminus. Arginase-1 Protein inhibits the growth of the arginine-depleting enzyme arginine deiminase (ADI)-resistant Hep3B tumor cells in mice.
Arginase-1 (ARG1) protein, crucial in the urea cycle, converts L-arginine to urea and L-ornithine. ARG1 also regulates L-arginine levels outside the liver, impacting immune responses. ARG1's release by granulocytes suppresses T cell and NK cell functions. In ILC2s, ARG1 promotes lung inflammation. However, ARG1's role in human monocytic/macrophage/dendritic cells is unclear. Arginase-1/ARG1 Protein, Human (N-His) is the recombinant human-derived Arginase-1/ARG1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of Arginase-1/ARG1 Protein, Human (N-His) is 322 a.a., with molecular weight of ~40 kDa.
Arginase-1 Protein, Human (HEK293, His) expresses in HEK293 cells with a His tag at the C-terminus. Arginase-1 Protein inhibits the growth of the arginine-depleting enzyme arginine deiminase (ADI)-resistant Hep3B tumor cells in mice.
The L1CAM protein is a neural cell adhesion molecule that plays a critical role in cell adhesion dynamics and initiation of tyrosine kinase receptor transmembrane signaling. Its importance spans brain development, affecting processes such as neuronal migration, axonal growth, fasciculations, and synaptogenesis. L1CAM Protein, Human (HEK293, His) is the recombinant human-derived L1CAM protein, expressed by HEK293 , with C-His labeled tag. The total length of L1CAM Protein, Human (HEK293, His) is 1101 a.a., with molecular weight of 160-200 kDa.
Neuronal cell adhesion molecule (NRCAM) is a member of the immunoglobulin superfamily and a cell adhesion protein. NRCAM is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system while being crucial for the saltatory propagation of action potentials along myelinated axons. NRCAM also plays a general role in cell-cell communication. NRCAM Protein, Human (HEK293, Fc) is the recombinant human-derived NRCAM protein, expressed by HEK293 , with C-hFc labeled tag. The total length of NRCAM Protein, Human (HEK293, Fc) is 576 a.a., with molecular weight of ~114.0 kDa.
CALM3 Protein, Tetronarce californica is the recombinant CALM3, expressed by E. coli , with tag Free labeled tag. The total length of CALM3 Protein, Tetronarce californica is 149 a.a., .
Arginase-1 (ARG1) plays a key role in the urea cycle, converting L-arginine into urea and L-ornithine. This cycle maintains L-arginine homeostasis, which is critical for nitric oxide synthase to compete for arginine. Arginase-1/ARG1 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Arginase-1/ARG1 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of Arginase-1/ARG1 Protein, Mouse (P.pastoris, His) is 323 a.a., with molecular weight of ~36.8 kDa.
The ALCAM/CD166 protein is a cell adhesion molecule that coordinates heterotypic and homotypic cell interactions, particularly with CD6. It promotes T cell activation, immune synapse formation, dendritic cell attachment, and inhibits endothelial cell migration while promoting tube formation. ALCAM/CD166 Protein, Mouse (HEK293, His) is the recombinant mouse-derived ALCAM/CD166 protein, expressed by HEK293 , with C-His labeled tag. The total length of ALCAM/CD166 Protein, Mouse (HEK293, His) is 500 a.a., with molecular weight of 70-100 kDa.
The ALCAM/CD166 protein is a cell adhesion molecule that mediates heterotypic and homotypic cell-to-cell contacts, promoting T cell activation, immune synapse formation, and LILRB4-mediated inhibition of T cell proliferation. ALCAM/CD166 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived ALCAM/CD166 protein, expressed by HEK293 , with C-His labeled tag. The total length of ALCAM/CD166 Protein, Human (Biotinylated, HEK293, His) is 499 a.a., with molecular weight of 70-80 kDa.
NCAM-1/CD56 protein is an important cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, and neurite outgrowth. It interacts with MDK and forms a complex with SLC39A6 and SLC39A10, complexly regulating NCAM-1 phosphorylation. NCAM-1/CD56 Protein, Mouse (HEK293, His) is the recombinant mouse-derived NCAM-1/CD56 protein, expressed by HEK293 , with C-His, C-10*His labeled tag.
CamK1; calcium/calmodulin-dependent protein kinase I; calcium/calmodulin-dependent protein kinase type 1; CamKI; Cam-KI; CamKI-alpha; Cam kinase I alpha; CamKI; MGC120317; MGC120318
CAMK1 alpha Protein, Human (sf9, His, GST) is the recombinant human-derived CAMK1 alpha, expressed by Sf9 insect cells , with His, GST labeled tag. The total length of CAMK1 alpha Protein, Human (sf9, His, GST) is 370 a.a.,
Arginase-2 (ARG2) is a multifunctional regulator central to the regulation of arginine metabolism and nitric oxide synthesis outside the urea cycle. In addition to its hepatic effects, ARG2 affects innate and adaptive immune responses, negatively affecting the survival of activated CD4(+) and CD8(+) T cells. Arginase-2/ARG2 Protein, Mouse (His-SUMO) is the recombinant mouse-derived Arginase-2/ARG2 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of Arginase-2/ARG2 Protein, Mouse (His-SUMO) is 332 a.a., with molecular weight of ~52.4 kDa.
The ALCAM/CD166 protein is a cell adhesion molecule that mediates heterotypic and homotypic cell-to-cell contacts, promoting T cell activation, immune synapse formation, and LILRB4-mediated inhibition of T cell proliferation. ALCAM/CD166 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived ALCAM/CD166 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of ALCAM/CD166 Protein, Human (Biotinylated, HEK293, His-Avi) is 499 a.a., with molecular weight of 72-80 kDa.
The ALCAM/CD166 protein is a cell adhesion molecule that coordinates heterotypic and homotypic cell interactions, particularly with CD6. It promotes T cell activation, immune synapse formation, dendritic cell attachment, and inhibits endothelial cell migration while promoting tube formation. ALCAM/CD166 Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived ALCAM/CD166 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of ALCAM/CD166 Protein, Mouse (Biotinylated, HEK293, His-Avi) is 500 a.a., with molecular weight of 75-85 kDa.
CALL3_HUMAN; CALML3; Calmodulin like 3; Calmodulin related protein NB 1; Calmodulin-like protein 3; Calmodulin-related protein NB-1; Cam like protein; Cam-like protein; CLP; OTTHUMP00000019004
The CALML3 protein has a dual role, acting as a specific light chain of unconventional myosin 10 (MYO10) and enhancing MYO10 translation. CALML3 has a potential molecular chaperone role and contributes to the synthesis of the emerging MYO10 heavy chain protein. CALML3 Protein, Human (GST) is the recombinant human-derived CALML3 protein, expressed by E. coli , with N-GST labeled tag. The total length of CALML3 Protein, Human (GST) is 149 a.a., with molecular weight of ~43.9 kDa.
BCAM Protein, acting as a laminin alpha-5 receptor, potentially participates in intracellular signaling, indicated by its resemblance to related proteins. BCAM Protein, Mouse (HEK293, His) is the recombinant mouse-derived BCAM protein, expressed by HEK293 , with C-His labeled tag. The total length of BCAM Protein, Mouse (HEK293, His) is 516 a.a., with molecular weight of 70-90 kDa.
Nectin-2/CD112 Protein, functioning as a laminin alpha-5 receptor, displays potential involvement in intracellular signaling, reflecting its similarity to related proteins. BCAM Protein, Rat (HEK293, His) is the recombinant rat-derived BCAM protein, expressed by HEK293 , with C-His labeled tag.
The EpCAM/TROP1 protein serves as a multifunctional molecule that promotes homogeneous interactions between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) in the mucosal epithelium. This suggests a crucial role in establishing an immune barrier against mucosal infection. EpCAM/TROP1 Protein, Rat (HEK293, His) is the recombinant rat-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-His labeled tag. The total length of EpCAM/TROP1 Protein, Rat (HEK293, His) is 243 a.a., with molecular weight of 30-36 kDa.
The EpCAM/TROP1 protein serves as a multifunctional molecule that promotes homogeneous interactions between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) in the mucosal epithelium. This suggests a crucial role in establishing an immune barrier against mucosal infection. EpCAM/TROP1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag.
Cadherin-1/CD324 protein, a calcium-dependent adhesion molecule, mediates cell processes. It interacts homophilically with other cadherin molecules, sorting and organizing cell types. CDH1 regulates adhesion, mobility, and proliferation of epithelial cells. It serves as an integrin ligand, suppressing invasion and promoting non-amyloidogenic degradation. CDH1 inhibits APP C99 and C83 production. Cadherin-1/CD324 Protein, Rat (HEK293, His) is the recombinant rat-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-His labeled tag.
Cadherin-1/CD324 protein, a calcium-dependent adhesion molecule, mediates cell processes. It interacts homophilically with other cadherin molecules, sorting and organizing cell types. CDH1 regulates adhesion, mobility, and proliferation of epithelial cells. It serves as an integrin ligand, suppressing invasion and promoting non-amyloidogenic degradation. CDH1 inhibits APP C99 and C83 production. Cadherin-1/CD324 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Cadherin-1/CD324 protein, expressed by HEK293, with C-hFc labeled tag. The total length of Cadherin-1/CD324 Protein, Rat (HEK293, Fc) is 690 a.a., with molecular weight of 95-130 kDa.
The Cadherin-1/CD324 protein is a calcium-dependent cell adhesion protein that interacts with homology in junctional cells to facilitate cell type sorting. CDH1 is involved in regulating intercellular adhesion, mobility, and epithelial cell proliferation. Cadherin-1/CD324 Protein, Human (HEK293, Fc) is the recombinant human-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-hFc labeled tag.
BCAM Protein, acting as a laminin alpha-5 receptor, potentially participates in intracellular signaling, indicated by its resemblance to related proteins. BCAM Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived BCAM protein, expressed by HEK293 , with C-hFc labeled tag. The total length of BCAM Protein, Mouse (HEK293, Fc) is 541 a.a., with molecular weight of 95-105 kDa.
EpCAM/TROP1 proteins play key roles in multiple processes as homogeneous interacting molecules that facilitate communication between mucosal epithelial midgut epithelial cells (IECs) and intraepithelial lymphocytes (IELs) to establish immunity against mucosal infections force. EpCAM/TROP1 Protein, Rhesus Macaque (HEK293) is the recombinant Rhesus Macaque-derived EpCAM/TROP1 protein, expressed by HEK293 , with tag free.
Neural cell adhesion molecule 1 (NCAM1) is a cell adhesion molecule which enables LRR domain binding activity and phosphatase binding activity. NCAM1 plays a role in the cell development and differentiation as well as immune surveillance. NCAM1 plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and activating FAK, MAPK and PI3K. FITC-Labeled NCAM-1/CD56 Protein, Human (HEK293, His) is the recombinant human-derived FITC-Labeled NCAM-1/CD56 protein, expressed by HEK293 , with C-His labeled tag. The total length of FITC-Labeled NCAM-1/CD56 Protein, Human (HEK293, His) is 699 a.a., with molecular weight of 90-116 kDa.
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. Animal-Free EpCAM/TROP1 Protein, Human (His) is the recombinant human-derived animal-FreeEpCAM/TROP1 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free EpCAM/TROP1 Protein, Human (His) is 242 a.a., with molecular weight of ~28.36 kDa.
ALCAM/CD166 protein is a multifunctional cell adhesion molecule involved in various cell-cell interactions. It promotes T cell activation and immune synapse formation by interacting with CD6. ALCAM/CD166 Protein, Rat (HEK293, Fc) is the recombinant rat-derived ALCAM/CD166 protein, expressed by HEK293 , with C-hFc labeled tag.
ALCAM/CD166 protein is a multifunctional cell adhesion molecule involved in various cell-cell interactions. It promotes T cell activation and immune synapse formation by interacting with CD6. ALCAM/CD166 Protein, Rat (HEK293, His) is the recombinant rat-derived ALCAM/CD166 protein, expressed by HEK293 , with C-His labeled tag. The total length of ALCAM/CD166 Protein, Rat (HEK293, His) is 500 a.a., with molecular weight of 68-95 kDa.
EpCAM/TROP1 proteins play key roles in multiple processes as homogeneous interacting molecules that facilitate communication between mucosal epithelial midgut epithelial cells (IECs) and intraepithelial lymphocytes (IELs) to establish immunity against mucosal infections force. EpCAM/TROP1 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag.
The Cadherin-1/CD324 protein is a calcium-dependent cell adhesion protein that interacts with homology in junctional cells to facilitate cell type sorting. CDH1 is involved in regulating intercellular adhesion, mobility, and epithelial cell proliferation. Cadherin-1/CD324 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Cadherin-1/CD324 Protein, Human (Biotinylated, HEK293, Fc) is 685 a.a., with molecular weight of ~87.1 KDa.
SHP-2 protein is a phosphatase enzyme that plays a crucial role in cell signaling. It is involved in regulating cellular processes such as cell growth, differentiation, and survival. Dysregulation of SHP-2 protein has been implicated in various diseases, including cancer and developmental disorders. EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, Fc) is the recombinant human-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, Fc) is 242 a.a., with molecular weight of ~54.1 KDa.
SHP-2 protein is a phosphatase enzyme that plays a crucial role in cell signaling. It is involved in regulating cellular processes such as cell growth, differentiation, and survival. Dysregulation of SHP-2 protein has been implicated in various diseases, including cancer and developmental disorders. EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived EpCAM/TROP1 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, His) is 242 a.a., with molecular weight of ~29 KDa.
Cadherin-1/CD324 is a calcium-dependent cell adhesion protein that orchestrates homogeneous interactions, promoting cell cohesion and potential cell type sorting. CDH1 regulates epithelial cell adhesion, mobility, and proliferation and acts as an invasive suppressor. Cadherin-1/CD324 Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-6*His labeled tag.
NCAM-1/CD56 protein is an important cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, and neurite outgrowth. It interacts with MDK and forms a complex with SLC39A6 and SLC39A10, complexly regulating NCAM-1 phosphorylation. NCAM-1/CD56 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived NCAM-1/CD56 protein, expressed by HEK293 , with C-His labeled tag. The total length of NCAM-1/CD56 Protein, Cynomolgus (HEK293, His) is 699 a.a., with molecular weight of 95-115 kDa.
The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Human (HEK293, His) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-6*His labeled tag.
Siglec-2/CD22 is a B cell surface receptor that mediates B cell interactions and is involved in B cell localization within lymphoid tissues. It selectively binds α-2,6-linked sialic acids, including CD45, and its sialic acid recognition site may be regulated by cis interactions. Siglec-2/CD22 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Siglec-2/CD22 Protein, Mouse (HEK293, His) is 681 a.a., with molecular weight of 95-130 kDa.
The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues.It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface.CD22 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived CD22 protein, expressed by HEK293 , with C-hFc labeled tag.
The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues.It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface.CD22 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived CD22 protein, expressed by HEK293 , with C-His labeled tag.
The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-2/CD22 Protein, Human (Biotinylated, HEK293, His) is 687 a.a., with molecular weight of ~76.6 KDa.
ETF1 Protein, Human is the recombinant human-derived ETF1, expressed by E. coli , with tag Free labeled tag. The total length of ETF1 Protein, Human is 135 a.a.,
BCAM Protein, operating as a laminin alpha-5 receptor, potentially engages in mediating intracellular signaling. BCAM Protein, Human (HEK293, His) is the recombinant human-derived BCAM protein, expressed by HEK293 , with C-6*His labeled tag.
The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Rat (HEK293, His) is the recombinant rat-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-His labeled tag.
The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-hFc labeled tag.
Siglec-2/CD22, a B-cell surface receptor, mediates B-cell interactions and participates in B-cell localization within lymphoid tissues. It selectively binds alpha-2,6-linked sialic acid, including CD45, with its sialic acid recognition site potentially regulated by cis interactions. In the immune response, ligand-induced tyrosine phosphorylation suggests a role in B-cell antigen receptor signaling modulation. It engages in both positive and inhibitory regulation by interacting with Src family kinases and recruiting cytoplasmic phosphatases via their SH2 domains. Interactions include LYN, SYK, PIK3R1/PIK3R2, PLCG1, SHC1, INPP5D, and GRB2 upon phosphorylation, as well as PTPN6/SHP-1 upon phosphorylation. Siglec-2/CD22 Protein, Mouse (Biotinylated, HEK293, His) is the recombinant mouse-derived Siglec-2/CD22 protein, expressed by HEK293 , with His labeled tag. The total length of Siglec-2/CD22 Protein, Mouse (Biotinylated, HEK293, His) is 681 a.a., with molecular weight of 90-110 kDa.
Cadherin-1/CD324 Protein, Human (HEK293, His) is a recombinant human E-cadherin produced in HEK293 cells, with His tag. Cadherin-1/CD324/E-cadherin is one of the most important molecules in cell-cell adhesion in epithelial tissues.
Siglec-2/CD22 Protein mediates B-cell B-cell interaction and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2/CD22 Protein, Mouse (AAA02562.1, HEK293, His) is the recombinant mouse-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Siglec-2/CD22 Protein, Mouse (AAA02562.1, HEK293, His) is 681 a.a., with molecular weight of 100-120 kDa.
VCAM-1/CD106 proteins expressed on endothelial cells critically regulate leukocyte adhesion through integrin interactions, initiating calcium channel activation and RAC1-mediated transendothelial migration during inflammation. VCAM-1/CD106 Protein, Human (HEK293, Fc) is the recombinant human-derived VCAM-1/CD106 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of VCAM-1/CD106 Protein, Human (HEK293, Fc) is 673 a.a., with molecular weight of 110-150 kDa.
VCAM-1 protein is a member of the immunoglobulin superfamily.It can act as a regulator of capillary formation and liver fibrosis, and can promote liver fibrosis.VCAM-1 Protein plays an important role in immune response and inflammatory response.VCAM-1/CD106 Protein, Mouse (HEK293, His) is the recombinant mouse-derived VCAM-1/CD106 protein, expressed by HEK293 , with C-His labeled tag.
Siglec-2/CD22 Protein, Mouse (690a.a, HEK293, Fc) is a Siglec of ~140 kDa with seven Ig-like domains and is expressed in a B-cell lineage-specific fashion, starting at the pre-B cell stage. CD22 is associated with membrane-bound IgM on the surface of B cells. Siglec-2 (CD22) specifically recognizes 伪2.6 sialic acid-containing glycans. Siglec-2 negatively regulates B cell antigen receptor (BCR) signaling by recruitment and activation of SH2-containing phosphatase 1 (SHP-1), which counteracts the phospharylation-mediated activation of signaling molecules by dephosphorylation, and reduces Ca2+ signaling by regulating the activity of the Ca2+ pump PMCA. Siglec-2/CD22 Protein, Mouse (690a.a, HEK293, Fc) is the recombinant mouse-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Siglec-2/CD22 Protein, Mouse (690a.a, HEK293, Fc) is 690 a.a., with molecular weight of ~125 kDa.
The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Human (512a.a, HEK293, His) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-2/CD22 Protein, Human (512a.a, HEK293, His) is 512 a.a., with molecular weight of 90-100 kDa.
VCAM-1 protein is a member of the immunoglobulin superfamily.It can act as a regulator of capillary formation and liver fibrosis, and can promote liver fibrosis.VCAM-1 Protein plays an important role in immune response and inflammatory response.VCAM-1/CD106 Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived VCAM-1/CD106 protein, expressed by HEK293 , with C-hFc, C-His labeled tag.
CaMKII beta/CAMK2B, a calcium/calmodulin-dependent protein kinase, autonomously functions after Ca(2+)/calmodulin-binding and autophosphorylation. It plays vital roles in dendritic spine and synapse formation, neuronal plasticity, and the regulation of sarcoplasmic reticulum Ca(2+) transport in skeletal muscle. In neurons, it contributes to actin cytoskeleton reorganization, dendritic arborization, and migration of developing neurons. Additionally, it modulates skeletal muscle function in response to exercise and participates in the JAK-STAT signaling pathway by phosphorylating STAT1. Moreover, it phosphorylates RETREG1, enhancing its reticulophagy activity under endoplasmic reticulum stress conditions. CaMKII beta/CAMK2B Protein, Human (sf9, His-GST) is the recombinant human-derived CaMKII beta/CAMK2B protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of CaMKII beta/CAMK2B Protein, Human (sf9, His-GST) is 503 a.a., with molecular weight of ~85 kDa.
The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Human (Biotinylated, 512a.a, HEK293, His) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-2/CD22 Protein, Human (Biotinylated, 512a.a, HEK293, His) is 512 a.a., with molecular weight of ~58.5 KDa.
SNAP25 is a key t-SNARE in neurotransmitter release, regulating synaptic function and plasma membrane recycling. It cooperates with CENPF to affect vesicle docking and membrane fusion. SNAP25 Protein, Human (His) is the recombinant human-derived SNAP25 protein, expressed by E. coli , with N-His labeled tag. The total length of SNAP25 Protein, Human (His) is 206 a.a., with molecular weight of ~28 kDa.
ERF1 protein, Human (sf9, GST) is the recombinant human-derived ERF1, expressed by Sf9 insect cells , with GST labeled tag. The total length of ERF1 protein, Human (sf9, GST) is 436 a.a.,
Neural cell adhesion molecule 1 (NCAM1) is a cell adhesion molecule which enables LRR domain binding activity and phosphatase binding activity. NCAM1 plays a role in the cell development and differentiation as well as immune surveillance. NCAM1 plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and activating FAK, MAPK and PI3K. NCAM-1/CD56 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived NCAM-1/CD56 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of NCAM-1/CD56 Protein, Human (Biotinylated, HEK293, His-Avi) is 584 a.a., with molecular weight of ~100 kDa.
Neural cell adhesion molecule 1 (NCAM1) is a cell adhesion molecule which enables LRR domain binding activity and phosphatase binding activity. NCAM1 plays a role in the cell development and differentiation as well as immune surveillance. NCAM1 plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and activating FAK, MAPK and PI3K. NCAM-1/CD56 Protein, Human (HEK293, His, solution) is the recombinant human-derived NCAM-1/CD56 protein, expressed by HEK293 , with C-His labeled tag. The total length of NCAM-1/CD56 Protein, Human (HEK293, His, solution) is 584 a.a., with molecular weight of ~66.1 kDa.
CaMKII beta/CAMK2B is a calcium/calmodulin-dependent protein kinase that functions autonomously upon Ca(2+)/calmodulin binding and autophosphorylation. It plays an important role in dendritic spine and synapse formation, neuronal plasticity, and the regulation of skeletal muscle sarcoplasmic reticulum Ca(2+) transport. CaMKII beta/CAMK2B Protein, Human (Q13554-1, sf9, GST) is the recombinant human-derived CaMKII beta/CAMK2B, expressed by Sf9 insect cells , with GST labeled tag. The total length of CaMKII beta/CAMK2B Protein, Human (Q13554-1, sf9, GST) is 665 a.a.,
CAMKI alpha/CAMK1 Protein, Human (HEK293, His), a recombinant human CAMK1 produced in HEK293 cells, has a His tag at the N-terminus. CAMK1 is involved in multiple cell functions, including calmodulin binding, ATP binding, signal transduction, development and cell differentiation.
Neural cell adhesion molecule 1 (NCAM1) is a cell adhesion molecule which enables LRR domain binding activity and phosphatase binding activity. NCAM1 plays a role in the cell development and differentiation as well as immune surveillance. NCAM1 plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and activating FAK, MAPK and PI3K. NCAM-1/CD56 Protein, Human (HEK293, His-Avi, Biotinylated) is the recombinant human-derived NCAM-1/CD56, expressed by HEK293 , with C-Avi, C-His labeled tag. ,
PDE1B protein, a cyclic nucleotide phosphodiesterase, displays dual specificity for cAMP and cGMP, essential second messengers in physiological processes. Preferring cGMP as a substrate, PDE1B fine-tunes cellular responses to cyclic nucleotide signaling. Its dual specificity underscores its regulatory role in diverse physiological pathways. PDE1B Protein, Human (sf9, His-GST) is the recombinant human-derived PDE1B protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of PDE1B Protein, Human (sf9, His-GST) is 536 a.a., with molecular weight of ~75 kDa.
Siglec-2/CD22 Protein mediates B-cell interactions, potentially guiding B-cell localization within lymphoid tissues. Recognizing sialylated glycoproteins, especially alpha-2,6-linked sialic acid, it engages in cis interactions on the cell surface. During the immune response, ligand-induced tyrosine phosphorylation suggests its role in B-cell antigen receptor signaling. Siglec-2/CD22 acts positively through Src kinases and inhibits by recruiting phosphatases. Existing as a monomer or heterodimer, its interactions with key molecules highlight a pivotal role in complex B-cell signaling. Further research is essential for precise molecular pathways and functional consequences. Siglec-2/CD22 Protein, Human (FITC, HEK293, Fc) is the recombinant human-derived Siglec-2/CD22 protein, expressed by HEK293, with C-hFc labeled tag. The total length of Siglec-2/CD22 Protein, Human (FITC, HEK293, Fc) is 668 a.a., with molecular weight of 130-140 kDa.
The Siglec-2/CD22 protein mediates B cell interactions and may direct B cell localization within lymphoid tissues. It recognizes sialylated glycoproteins, especially α-2,6-linked sialic acid, and participates in cis-interactions at the cell surface. Siglec-2/CD22 Protein, Rhesus macaque (HEK293, His) is the recombinant Rhesus Macaque-derived Siglec-2/CD22 protein, expressed by HEK293 , with C-His labeled tag. The total length of Siglec-2/CD22 Protein, Rhesus macaque (HEK293, His) is 667 a.a., with molecular weight of 100-120 kDa.
The L1CAM protein is a neural cell adhesion molecule that plays a critical role in cell adhesion dynamics and initiation of tyrosine kinase receptor transmembrane signaling. Its importance spans brain development, affecting processes such as neuronal migration, axonal growth, fasciculations, and synaptogenesis. L1CAM Protein, Human (HEK293, C-His) is the recombinant human-derived L1CAM protein, expressed by HEK293 , with C-10*His labeled tag.
CAMK2D protein regulates calcium levels and excitation-contraction coupling in the heart. CaMKII delta/CAMK2D Protein, Human (Sf9, GST) is the recombinant human-derived CAMK2D protein, expressed by Sf9 insect cells , with N-GST labeled tag.
Cadherin-1/CD324 Protein, a calcium-dependent receptor on myeloid cells, binds to carbohydrates on neutrophils and monocytes. It facilitates interaction between activated endothelial cells or platelets with leukocytes. It recognizes sialyl-Lewis X as its ligand. Through interaction with SELPLG, it mediates rapid leukocyte rolling in early inflammation. Cadherin-1/CD324 Protein also interacts with SNX17 and facilitates neutrophil adhesion and rolling, depending on sialyl-Lewis X epitope and tyrosine sulfation. Cadherin-1/CD324 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Cadherin-1/CD324 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-1/CD324 Protein, Cynomolgus (HEK293, His) is 554 a.a., with molecular weight of 68-78 kDa.
Eltrombopag- 13C4 (SB-497115- 13C4) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .
Calmodulin Antibody (YA1827) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1827), targeting Calmodulin, with a predicted molecular weight of 17 kDa (observed band size: 17 kDa). Calmodulin Antibody (YA1827) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.
VCam1; L1Cam; Vascular cell adhesion protein 1; V-Cam 1; VCam-1; INCam-100; CD antigen CD106
WB, IHC-P, IP
Human, Mouse, Rat
VCAM1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 81 kDa, targeting to VCAM1. It can be used for WB,IHC-P,IP assays with tag free, in the background of Human, Mouse, Rat.
Bravo; hBravo; Neuronal cell adhesion molecule; Ng Cam related; NgCam related cell adhesion molecule; Nr Cam; NrCam
WB, IHC-P, IHC-F, ICC/IF, ELISA
Human
NrCAM Antibody (YA2444) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2444), targeting NrCAM, with a predicted molecular weight of 144 kDa (observed band size: 144 kDa). NrCAM Antibody (YA2444) can be used for WB, IP experiment in human background.
CaMK1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 41 kDa, targeting to CaMK1. It can be used for WB assays with tag free, in the background of Mouse, Rat.
Calcium/calmodulin dependent protein kinase beta; Calcium/calmodulin dependent protein kinase kinase 2; Calcium/calmodulin dependent protein kinase kinase beta; Cam kinase kinase beta; Cam KK beta; CamKK 2; CamKK; CamKK beta; CamKK beta protein; CamKKB.
WB, IHC-P, IHC-F, FC,
Human, Mouse, Rat, Sheep
CAMKK2 Antibody is an unconjugated, approximately 55 kDa, rabbit-derived, anti-CAMKK2 polyclonal antibody. CAMKK2 Antibody can be used for: WB, IHC-P, IHC-F, Flow-Cyt, expriments in human, mouse, rat, sheep, and predicted: pig, cow, horse background without labeling.
Cam kinase 2 delta; Cam kinase II delta; Cam kinase II delta subunit; Cam kinase II subunit delta; CamK 2d; CamK-II delta subunit; CamK2D; CamKI
WB
Human, Rat
CaMKII delta Antibody (YA2337) is a non-conjugated IgG antibody, targeting CaMKII delta, with a predicted molecular weight of 56 kDa (observed band size: 56 kDa). CaMKII delta Antibody (YA2337) can be used for WB experiment in human, rat background.
L1CAM Antibody (YA3149) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3149), targeting L1CAM, with a predicted molecular weight of 140 kDa (observed band size: 140 kDa). L1CAM Antibody (YA3149) can be used for WB, IHC-P experiment in human background.
KRIT1 Antibody (YA3147) is a non-conjugated IgG antibody, targeting KRIT1, with a predicted molecular weight of 84 kDa (observed band size: 84 kDa). KRIT1 Antibody (YA3147) can be used for WB experiment in human, mouse, rat background.
CD171 Antibody (YA1370) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1370), targeting CD171. CD171 Antibody (YA1370) can be used for FC, ELISA experiment in human background.
Arginase 2 Antibody (YA2893) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2893), targeting Arginase 2, with a predicted molecular weight of 39 kDa (observed band size: 39 kDa). Arginase 2 Antibody (YA2893) can be used for WB, ICC/IF, FC experiment in human background.
E Cadherin Antibody is a rabbit-derived non-conjugated IgG antibody , targeting E Cadherin, with a predicted molecular weight of 97 kDa (observed band size: 135 kDa). E Cadherin Antibody can be used for WB, IHC-P, IHC-F, ICC/IF, ELISA experiment in human, mouse, rat background.
ABL2 Antibody (YA3203) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3203), targeting ABL2, with a predicted molecular weight of 128 kDa (observed band size: 128 kDa). ABL2 Antibody (YA3203) can be used for WB, FC experiment in human, mouse, rat background.
CamK2B; Cam2; CamK2; CamKB; Calcium/calmodulin-dependent protein kinase type II subunit beta; Cam kinase II subunit beta; CamK-II subunit beta; CamK2G; CamK; CamK-II; CamKG; Calcium/calmodulin-dependent protein kinase type II subunit gamma
WB
Mouse
CaMKII beta Antibody (YA2344) is a non-conjugated IgG antibody, targeting CaMKII beta, with a predicted molecular weight of 73 kDa (observed band size: 54 kDa). CaMKII beta Antibody (YA2344) can be used for WB experiment in mouse background.
CamK4; CamK; CamK-GR; CamKIV; Calcium/calmodulin-dependent protein kinase type IV; CamK IV; Cam kinase-GR
WB
Human
CAMKIV Antibody (YA942) is a non-conjugated IgG2a antibody, targeting CAMKIV, with a predicted molecular weight of 52 kDa (observed band size: 55 kDa). CAMKIV Antibody (YA942) can be used for WB experiment in human background.
CamK4; CamK; CamK-GR; CamKIV; Calcium/calmodulin-dependent protein kinase type IV; CamK IV; Cam kinase-GR
WB, IHC-P, ICC/IF, IP, FC
Human
CAMKIV Antibody (YA943) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA943), targeting CAMKIV, with a predicted molecular weight of 52 kDa (observed band size: 52 kDa). CAMKIV Antibody (YA943) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human background.
NCAM1 Antibody (YA3222) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3222), targeting NCAM1, with a predicted molecular weight of 95 kDa (observed band size: 180 kDa). NCAM1 Antibody (YA3222) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human background.
Alpha CamKII; Calcium calmodulin dependent protein kinase II; Calcium/calmodulin dependent protein kinase II alpha B subunit; Calcium/calmodulin dependent protein kinase type II alpha chain; Calcium/calmodulin-dependent protein kinase (Cam kinase) II alpha; Calcium/calmodulin-dependent protein kinase II alpha; Calcium/calmodulin-dependent protein kinase II-alpha; Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase type IIA; Cam kinase II alpha chain; Cam kinase II alpha subunit; Cam kinase II subunit alpha; CamK II alpha subunit; CamK-II subunit alpha; Camk2a; CamKA; CamKII; CamKIINalpha; EC2.7.11.17; KCC2A_HUMAN; KIAA0968; MGC123320; MGC139375; MGC155201; mKIAA0968; PK2CDD; PKCCD; R74975; zgc:112538; zgc:123320;
WB, IP, FC, IHC-P
Human, Mouse, Rat
CaMKII alpha Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 54 kDa, targeting to CaMKII alpha. It can be used for WB,IP,FC,IHC-P assays with tag free, in the background of Human, Mouse, Rat.
Phospho-E Cadherin (Ser838/Ser840) Antibody (YA2579) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2579), targeting Phospho-E Cadherin (Ser838/Ser840), with a predicted molecular weight of 97 kDa (observed band size: 135 kDa). Phospho-E Cadherin (Ser838/Ser840) Antibody (YA2579) can be used for WB, IHC-P, IP experiment in human, mouse background.
Calcineurin A Antibody (YA2508) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2508), targeting Calcineurin A, with a predicted molecular weight of 59 kDa (observed band size: 59 kDa). Calcineurin A Antibody (YA2508) can be used for WB, ICC/IF, FC experiment in human, mouse, rat background.
L1CAM Human Pre-designed siRNA Set A contains three designed siRNAs for L1CAM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cho-Arg TFA is a steroid-based cationic lipid with an L-Arginine headgroup. Cho-Arg TFA shows a remarkably high optimized plasmid DNA transfection efficacy .
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