HAPLN1 - hyaluronan and proteoglycan link protein 1 Gene

Homo sapiens

Also known as CRT1; CRTL1

Gene ID: 1404 | Gene type: protein coding

About HAPLN1

Cytogenetic location: 5q14.3 Genomic coordinates (GRCh38): 5:83,637,805-83,720,855 (from NCBI)

This gene has 7 transcripts (splice variants), 206 orthologues and 7 paralogues. Biased expression in placenta (RPKM 20.1), small intestine (RPKM 4.0) and 5 other tissues.

Summary

Predicted to enable hyaluronic acid binding activity. Predicted to be an extracellular matrix structural constituent conferring compression resistance. Predicted to be involved in central nervous system development and skeletal system development. Colocalizes with collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

HAPLN1 Products(1)

mRNA	Protein	Name
NM_001884.4	NP_001875.1	hyaluronan and proteoglycan link protein 1 precursor

HAPLN1 Protein Structure

V-set

Xlink

0
100
200
300
354 a.a.

Protein Preferred Names

Protein Names

hyaluronan and proteoglycan link protein 1

Cartilage link protein

HAPLN1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	CRYAA	P02489	HEL-S-101	Homo sapiens	V9HW27	Validated Y2H	25416956
Intra	CRYAA	P02489	HEL-S-101	Homo sapiens	V9HW27	Y2H Array	25416956
Intra	CRYAA	P02489	SGSM1	Homo sapiens	Q2NKQ1-4	Validated Y2H	32814053
Intra	CRYAA	P02489	SGSM1	Homo sapiens	Q2NKQ1-4	Y2H Pooling	32814053
Intra	CRYAA	P02489	SGSM1	Homo sapiens	Q2NKQ1-4	Y2H Array	32814053
Intra	CRYAA	P02489	ESRP1	Homo sapiens	Q6NXG1	Y2H Array	32814053
Intra	CRYAA	P02489	ESRP1	Homo sapiens	Q6NXG1	Y2H Pooling	32814053
Intra	CRYAA	P02489	ESRP1	Homo sapiens	Q6NXG1	Validated Y2H	32814053
Intra	CRYAA	P02489	KRTAP19-7	Homo sapiens	Q3SYF9	Validated Y2H	32814053
Intra	CRYAA	P02489	KRTAP19-7	Homo sapiens	Q3SYF9	Y2H Array	32814053
Intra	CRYAA	P02489	KRTAP19-7	Homo sapiens	Q3SYF9	Y2H Pooling	32814053
Intra	CRYAA	P02489	COX4I1	Homo sapiens	Q86WV2	Validated Y2H	32814053
Intra	CRYAA	P02489	COX4I1	Homo sapiens	Q86WV2	Y2H Array	32814053
Intra	CRYAA	P02489	COX4I1	Homo sapiens	Q86WV2	Y2H Pooling	32814053
Intra	CRYAA	P02489	KRTAP8-1	Homo sapiens	Q8IUC2	Validated Y2H	32814053
Intra	CRYAA	P02489	KRTAP8-1	Homo sapiens	Q8IUC2	Y2H Pooling	32814053
Intra	CRYAA	P02489	KRTAP8-1	Homo sapiens	Q8IUC2	Y2H Array	32814053
Intra	CRYAA	P02489	NEUROG1	Homo sapiens	Q92886	Y2H Array	32814053
Intra	CRYAA	P02489	NEUROG1	Homo sapiens	Q92886	Y2H Pooling	32814053
Intra	CRYAA	P02489	NEUROG1	Homo sapiens	Q92886	Validated Y2H	32814053
Intra	CRYAA	P02489	WBP1L	Homo sapiens	Q9NX94	Validated Y2H	32814053
Intra	CRYAA	P02489	WBP1L	Homo sapiens	Q9NX94	Y2H Array	32814053
Intra	CRYAA	P02489	WBP1L	Homo sapiens	Q9NX94	Y2H Pooling	32814053
Intra	CRYAA	P02489	KRTAP19-5	Homo sapiens	Q3LI72	Y2H Pooling	32814053
Intra	CRYAA	P02489	KRTAP19-5	Homo sapiens	Q3LI72	Validated Y2H	32814053
Intra	CRYAA	P02489	KRTAP19-5	Homo sapiens	Q3LI72	Y2H Array	32814053
Intra	CRYAA	P02489	UBE2V1	Homo sapiens	Q13404	Validated Y2H	32814053
Intra	CRYAA	P02489	UBE2V1	Homo sapiens	Q13404	Y2H Array	32814053
Intra	CRYAA	P02489	UBE2V1	Homo sapiens	Q13404	Y2H Pooling	32814053
Intra	CRYAA	P02489	NOD1	Homo sapiens	Q9Y239	Validated Y2H	32814053
Intra	CRYAA	P02489	NOD1	Homo sapiens	Q9Y239	Y2H Pooling	32814053
Intra	CRYAA	P02489	NOD1	Homo sapiens	Q9Y239	Y2H Array	32814053
Intra	CRYAA	P02489	LARP4B	Homo sapiens	Q92615	Y2H Array	32814053
Intra	CRYAA	P02489	LARP4B	Homo sapiens	Q92615	Y2H Pooling	32814053
Intra	CRYAA	P02489	LARP4B	Homo sapiens	Q92615	Validated Y2H	32814053
Intra	CRYAA	P02489	METTL13	Homo sapiens	Q8N6R0	Validated Y2H	32814053
Intra	CRYAA	P02489	METTL13	Homo sapiens	Q8N6R0	Y2H Pooling	32814053
Intra	CRYAA	P02489	METTL13	Homo sapiens	Q8N6R0	Y2H Array	32814053
Intra	CRYAA	P02489	POLR1C	Homo sapiens	O15160	Validated Y2H	32814053
Intra	CRYAA	P02489	POLR1C	Homo sapiens	O15160	Y2H Pooling	32814053
Intra	CRYAA	P02489	POLR1C	Homo sapiens	O15160	Y2H Array	32814053
Intra	CRYAA	P02489	SDCCAG8	Homo sapiens	Q86SQ7-2	Y2H Pooling	32814053
Intra	CRYAA	P02489	SDCCAG8	Homo sapiens	Q86SQ7-2	Validated Y2H	32814053
Intra	CRYAA	P02489	SDCCAG8	Homo sapiens	Q86SQ7-2	Y2H Array	32814053
Intra	CRYAA	P02489	KIF1B	Homo sapiens	O60333-2	Y2H Pooling	32814053
Intra	CRYAA	P02489	KIF1B	Homo sapiens	O60333-2	Validated Y2H	32814053
Intra	CRYAA	P02489	KIF1B	Homo sapiens	O60333-2	Y2H Array	32814053
Intra	CRYAA	P02489	CDK8	Homo sapiens	P49336-2	Validated Y2H	32814053
Intra	CRYAA	P02489	CDK8	Homo sapiens	P49336-2	Y2H Array	32814053
Intra	CRYAA	P02489	CDK8	Homo sapiens	P49336-2	Y2H Pooling	32814053
Intra	CRYAA	P02489	FAM163A	Homo sapiens	Q96GL9	Y2H Array	32814053
Intra	CRYAA	P02489	FAM163A	Homo sapiens	Q96GL9	Validated Y2H	32814053
Intra	CRYAA	P02489	FAM163A	Homo sapiens	Q96GL9	Y2H Pooling	32814053
Intra	CRYAA	P02489	UQCC1	Homo sapiens	Q9NVA1	Y2H Pooling	32814053
Intra	CRYAA	P02489	UQCC1	Homo sapiens	Q9NVA1	Validated Y2H	32814053
Intra	CRYAA	P02489	UQCC1	Homo sapiens	Q9NVA1	Y2H Array	32814053
Intra	CRYAA	P02489	ZNF444	Homo sapiens	Q8N0Y2-2	Y2H Array	32814053
Intra	CRYAA	P02489	ZNF444	Homo sapiens	Q8N0Y2-2	Validated Y2H	32814053
Intra	CRYAA	P02489	ZNF444	Homo sapiens	Q8N0Y2-2	Y2H Pooling	32814053
Intra	CRYAA	P02489	FAAP20	Homo sapiens	Q6NZ36-4	Validated Y2H	32814053
Intra	CRYAA	P02489	FAAP20	Homo sapiens	Q6NZ36-4	Y2H Array	32814053
Intra	CRYAA	P02489	FAAP20	Homo sapiens	Q6NZ36-4	Y2H Pooling	32814053
Intra	CRYAA	P02489	WWOX	Homo sapiens	Q9NZC7-5	Validated Y2H	32814053
Intra	CRYAA	P02489	WWOX	Homo sapiens	Q9NZC7-5	Y2H Array	32814053
Intra	CRYAA	P02489	WWOX	Homo sapiens	Q9NZC7-5	Y2H Pooling	32814053
Intra	CRYAA	P02489	TEX12	Homo sapiens	Q9BXU0	Y2H Pooling	32814053
Intra	CRYAA	P02489	TEX12	Homo sapiens	Q9BXU0	Validated Y2H	32814053
Intra	CRYAA	P02489	TEX12	Homo sapiens	Q9BXU0	Y2H Array	32814053
Intra	CRYAA	P02489	C11orf54	Homo sapiens	Q9H0W9-3	Y2H Pooling	32814053
Intra	CRYAA	P02489	C11orf54	Homo sapiens	Q9H0W9-3	Validated Y2H	32814053
Intra	CRYAA	P02489	C11orf54	Homo sapiens	Q9H0W9-3	Y2H Array	32814053
Intra	CRYAA	P02489	RBFOX1	Homo sapiens	Q9NWB1-5	Validated Y2H	32814053
Intra	CRYAA	P02489	RBFOX1	Homo sapiens	Q9NWB1-5	Y2H Pooling	32814053
Intra	CRYAA	P02489	RBFOX1	Homo sapiens	Q9NWB1-5	Y2H Array	32814053
Intra	CRYAA	P02489	CD209	Homo sapiens	Q9NNX6-10	Y2H Pooling	32814053
Intra	CRYAA	P02489	CD209	Homo sapiens	Q9NNX6-10	Validated Y2H	32814053
Intra	CRYAA	P02489	CD209	Homo sapiens	Q9NNX6-10	Y2H Array	32814053
Intra	CRYAA	P02489	GRB10	Homo sapiens	Q13322-4	Y2H Array	32814053
Intra	CRYAA	P02489	GRB10	Homo sapiens	Q13322-4	Validated Y2H	32814053
Intra	CRYAA	P02489	GRB10	Homo sapiens	Q13322-4	Y2H Pooling	32814053
Intra	CRYAA	P02489	UNKL	Homo sapiens	Q9H9P5-5	Y2H Pooling	32814053
Intra	CRYAA	P02489	UNKL	Homo sapiens	Q9H9P5-5	Validated Y2H	32814053
Intra	CRYAA	P02489	UNKL	Homo sapiens	Q9H9P5-5	Y2H Array	32814053
Intra	CRYAA	P02489	IL16	Homo sapiens	Q14005-2	Y2H Pooling	32814053
Intra	CRYAA	P02489	IL16	Homo sapiens	Q14005-2	Validated Y2H	32814053
Intra	CRYAA	P02489	IL16	Homo sapiens	Q14005-2	Y2H Array	32814053
Intra	CRYAA	P02489	PANX2	Homo sapiens	Q495U3	Y2H Pooling	32814053
Intra	CRYAA	P02489	PANX2	Homo sapiens	Q495U3	Validated Y2H	32814053
Intra	CRYAA	P02489	PANX2	Homo sapiens	Q495U3	Y2H Array	32814053
Intra	CRYAA	P02489	HOXB1	Homo sapiens	Q4VB01	Y2H Pooling	32814053
Intra	CRYAA	P02489	HOXB1	Homo sapiens	Q4VB01	Validated Y2H	32814053
Intra	CRYAA	P02489	HOXB1	Homo sapiens	Q4VB01	Y2H Array	32814053
Intra	CRYAA	P02489	CDCA4	Homo sapiens	Q9BXL8	Y2H Array	32814053
Intra	CRYAA	P02489	CDCA4	Homo sapiens	Q9BXL8	Validated Y2H	32814053
Intra	CRYAA	P02489	CDCA4	Homo sapiens	Q9BXL8	Y2H Pooling	32814053
Intra	CRYAA	P02489	CRYBB3	Homo sapiens	P26998	Y2H Array	32814053
Intra	CRYAA	P02489	CRYBB3	Homo sapiens	P26998	Validated Y2H	32814053
Intra	CRYAA	P02489	CRYBB3	Homo sapiens	P26998	Y2H Pooling	32814053
Intra	CRYAA	P02489	ESRP1	Homo sapiens	Q6NXG1-3	Y2H Pooling	32814053
Intra	CRYAA	P02489	ESRP1	Homo sapiens	Q6NXG1-3	Validated Y2H	32814053
Intra	CRYAA	P02489	ESRP1	Homo sapiens	Q6NXG1-3	Y2H Array	32814053
Intra	CRYAA	P02489	RNF34	Homo sapiens	Q969K3	Validated Y2H	32814053
Intra	CRYAA	P02489	RNF34	Homo sapiens	Q969K3	Y2H Pooling	32814053
Intra	CRYAA	P02489	RNF34	Homo sapiens	Q969K3	Y2H Array	32814053
Intra	CRYAA	P02489	TIMM17B	Homo sapiens	O60830	Y2H Array	32814053
Intra	CRYAA	P02489	TIMM17B	Homo sapiens	O60830	Y2H Pooling	32814053
Intra	CRYAA	P02489	TIMM17B	Homo sapiens	O60830	Validated Y2H	32814053
Intra	CRYAA	P02489	TNIP3	Homo sapiens	Q96KP6	Validated Y2H	32814053
Intra	CRYAA	P02489	TNIP3	Homo sapiens	Q96KP6	Y2H Array	32814053
Intra	CRYAA	P02489	TNIP3	Homo sapiens	Q96KP6	Y2H Pooling	32814053
Intra	CRYAA	P02489	COL9A1	Homo sapiens	P20849	Y2H Array	32814053
Intra	CRYAA	P02489	COL9A1	Homo sapiens	P20849	Y2H Pooling	32814053
Intra	CRYAA	P02489	COL9A1	Homo sapiens	P20849	Validated Y2H	32814053
Intra	CRYAA	P02489	ZHX1-C8orf76	Homo sapiens	Q96EF9	Validated Y2H	32814053
Intra	CRYAA	P02489	ZHX1-C8orf76	Homo sapiens	Q96EF9	Y2H Pooling	32814053
Intra	CRYAA	P02489	ZHX1-C8orf76	Homo sapiens	Q96EF9	Y2H Array	32814053
Intra	CRYAA	P02489	RGR	Homo sapiens	P47804-3	Y2H Array	32814053
Intra	CRYAA	P02489	RGR	Homo sapiens	P47804-3	Validated Y2H	32814053
Intra	CRYAA	P02489	RGR	Homo sapiens	P47804-3	Y2H Pooling	32814053
Intra	CRYAA	P02489	PPP1R21	Homo sapiens	Q6ZMI0-5	Validated Y2H	32814053
Intra	CRYAA	P02489	PPP1R21	Homo sapiens	Q6ZMI0-5	Y2H Pooling	32814053
Intra	CRYAA	P02489	PPP1R21	Homo sapiens	Q6ZMI0-5	Y2H Array	32814053
Intra	CRYAA	P02489	SCAPER	Homo sapiens	Q9BY12-3	Y2H Pooling	32814053
Intra	CRYAA	P02489	SCAPER	Homo sapiens	Q9BY12-3	Validated Y2H	32814053
Intra	CRYAA	P02489	SCAPER	Homo sapiens	Q9BY12-3	Y2H Array	32814053
Intra	CRYAA	P02489	RFFL	Homo sapiens	Q8WZ73-3	Y2H Pooling	32814053
Intra	CRYAA	P02489	RFFL	Homo sapiens	Q8WZ73-3	Validated Y2H	32814053
Intra	CRYAA	P02489	RFFL	Homo sapiens	Q8WZ73-3	Y2H Array	32814053
Intra	CRYAA	P02489	TMPRSS6	Homo sapiens	Q8IU80-2	Y2H Array	32814053
Intra	CRYAA	P02489	TMPRSS6	Homo sapiens	Q8IU80-2	Y2H Pooling	32814053
Intra	CRYAA	P02489	TMPRSS6	Homo sapiens	Q8IU80-2	Validated Y2H	32814053
Intra	CRYAA	P02489	SPSB1	Homo sapiens	Q96BD6	Validated Y2H	32814053
Intra	CRYAA	P02489	SPSB1	Homo sapiens	Q96BD6	Y2H Array	32814053
Intra	CRYAA	P02489	SPSB1	Homo sapiens	Q96BD6	Y2H Pooling	32814053
Intra	CRYAA	P02489	ADD1	Homo sapiens	P35611	Validated Y2H	32814053
Intra	CRYAA	P02489	ADD1	Homo sapiens	P35611	Y2H Array	32814053
Intra	CRYAA	P02489	ADD1	Homo sapiens	P35611	Y2H Pooling	32814053
Intra	CRYAA	P02489	RBM4	Homo sapiens	Q9BWF3	Y2H Pooling	32814053
Intra	CRYAA	P02489	RBM4	Homo sapiens	Q9BWF3	Validated Y2H	32814053
Intra	CRYAA	P02489	RBM4	Homo sapiens	Q9BWF3	Y2H Array	32814053
Intra	CRYAA	P02489	PRAM1	Homo sapiens	Q96QH2	Y2H Array	32814053
Intra	CRYAA	P02489	PRAM1	Homo sapiens	Q96QH2	Y2H Pooling	32814053
Intra	CRYAA	P02489	PRAM1	Homo sapiens	Q96QH2	Validated Y2H	32814053
Intra	CRYAA	P02489	ARFGAP3	Homo sapiens	Q9NP61	Y2H Array	32814053
Intra	CRYAA	P02489	ARFGAP3	Homo sapiens	Q9NP61	Y2H Pooling	32814053
Intra	CRYAA	P02489	ARFGAP3	Homo sapiens	Q9NP61	Validated Y2H	32814053
Intra	CRYAA	P02489	MAPK11	Homo sapiens	Q15759	Y2H Array	32814053
Intra	CRYAA	P02489	MAPK11	Homo sapiens	Q15759	Validated Y2H	32814053
Intra	CRYAA	P02489	MAPK11	Homo sapiens	Q15759	Y2H Pooling	32814053
Intra	CRYAA	P02489	DUSP10	Homo sapiens	Q9Y6W6	Y2H Pooling	32814053
Intra	CRYAA	P02489	DUSP10	Homo sapiens	Q9Y6W6	Validated Y2H	32814053
Intra	CRYAA	P02489	DUSP10	Homo sapiens	Q9Y6W6	Y2H Array	32814053
Intra	CRYAA	P02489	EIF3E	Homo sapiens	P60228	Validated Y2H	32814053
Intra	CRYAA	P02489	EIF3E	Homo sapiens	P60228	Y2H Array	32814053
Intra	CRYAA	P02489	EIF3E	Homo sapiens	P60228	Y2H Pooling	32814053
Intra	CRYAA	P02489	HSPB1	Homo sapiens	P04792	Anti Bait CoIP	12601044
Intra	CRYAA	P02489	HSPB1	Homo sapiens	P04792	Pull Down	11700327
Intra	CRYAA	P02489	HSPB1	Homo sapiens	P04792	Validated Y2H	32814053
Intra	CRYAA	P02489	HSPB1	Homo sapiens	P04792	Y2H Pooling	32814053
Intra	CRYAA	P02489	HSPB1	Homo sapiens	P04792	Anti Tag CoIP	33961781
Intra	CRYAA	P02489	HSPB1	Homo sapiens	P04792	Y2H Array	32814053
Intra	CRYAA	P02489	RPSA	Homo sapiens	P08865	Y2H Array	32814053
Intra	CRYAA	P02489	RPSA	Homo sapiens	P08865	Y2H Pooling	32814053
Intra	CRYAA	P02489	RPSA	Homo sapiens	P08865	Validated Y2H	32814053
Intra	CRYAA	P02489	SPRY4	Homo sapiens	Q9C004	Validated Y2H	32814053
Intra	CRYAA	P02489	SPRY4	Homo sapiens	Q9C004	Y2H Pooling	32814053
Intra	CRYAA	P02489	SPRY4	Homo sapiens	Q9C004	Y2H Array	32814053
Intra	CRYAA	P02489	PSME3	Homo sapiens	P61289	Validated Y2H	32814053
Intra	CRYAA	P02489	PSME3	Homo sapiens	P61289	Y2H Array	32814053
Intra	CRYAA	P02489	PSME3	Homo sapiens	P61289	Y2H Pooling	32814053
Intra	CRYAA	P02489	NUDC	Homo sapiens	Q9Y266	Y2H Array	32814053
Intra	CRYAA	P02489	NUDC	Homo sapiens	Q9Y266	Y2H Pooling	32814053
Intra	CRYAA	P02489	NUDC	Homo sapiens	Q9Y266	Validated Y2H	32814053
Intra	CRYAA	P02489	PTTG1IP	Homo sapiens	P53801	Y2H Pooling	32814053
Intra	CRYAA	P02489	PTTG1IP	Homo sapiens	P53801	Validated Y2H	32814053
Intra	CRYAA	P02489	PTTG1IP	Homo sapiens	P53801	Y2H Array	32814053
Intra	CRYAA	P02489	TSPAN2	Homo sapiens	O60636	Y2H Array	32814053
Intra	CRYAA	P02489	TSPAN2	Homo sapiens	O60636	Validated Y2H	32814053
Intra	CRYAA	P02489	TSPAN2	Homo sapiens	O60636	Y2H Pooling	32814053
Intra	CRYAA	P02489	TCP10L	Homo sapiens	Q8TDR4	Y2H Pooling	32814053
Intra	CRYAA	P02489	TCP10L	Homo sapiens	Q8TDR4	Validated Y2H	32814053
Intra	CRYAA	P02489	TCP10L	Homo sapiens	Q8TDR4	Y2H Array	32814053
Intra	CRYAA	P02489	SPATS1	Homo sapiens	Q496A3	Y2H Array	32814053
Intra	CRYAA	P02489	SPATS1	Homo sapiens	Q496A3	Validated Y2H	32814053
Intra	CRYAA	P02489	SPATS1	Homo sapiens	Q496A3	Y2H Pooling	32814053
Intra	CRYAA	P02489	EGFL8	Homo sapiens	Q99944	Lumier	32814053
Intra	CRYAA	P02489	POLR2E	Homo sapiens	P19388	Validated Y2H	32814053
Intra	CRYAA	P02489	POLR2E	Homo sapiens	P19388	Y2H Array	32814053
Intra	CRYAA	P02489	POLR2E	Homo sapiens	P19388	Y2H Pooling	32814053
Intra	CRYAA	P02489	HTT	Homo sapiens	P42858	Validated Y2H	32814053
Intra	CRYAA	P02489	HTT	Homo sapiens	P42858	Y2H Pooling	32814053
Intra	CRYAA	P02489	HTT	Homo sapiens	P42858	Y2H Array	32814053
Intra	CRYAA	P02489	MAP3K5	Homo sapiens	Q99683	Validated Y2H	32814053
Intra	CRYAA	P02489	MAP3K5	Homo sapiens	Q99683	Y2H Array	32814053
Intra	CRYAA	P02489	MAP3K5	Homo sapiens	Q99683	Y2H Pooling	32814053
Intra	CRYAA	P02489	HTRA2	Homo sapiens	O43464	Y2H Pooling	32814053
Intra	CRYAA	P02489	HTRA2	Homo sapiens	O43464	Validated Y2H	32814053
Intra	CRYAA	P02489	HTRA2	Homo sapiens	O43464	Y2H Array	32814053
Intra	CRYAA	P02489	GABPB1	Homo sapiens	Q06547-2	Y2H Array	32814053
Intra	CRYAA	P02489	GABPB1	Homo sapiens	Q06547-2	Y2H Pooling	32814053
Intra	CRYAA	P02489	GABPB1	Homo sapiens	Q06547-2	Validated Y2H	32814053
Intra	CRYAA	P02489	INCA1	Homo sapiens	Q0VD86	Y2H Pooling	32814053
Intra	CRYAA	P02489	INCA1	Homo sapiens	Q0VD86	Validated Y2H	32814053
Intra	CRYAA	P02489	INCA1	Homo sapiens	Q0VD86	Y2H Array	32814053
Intra	CRYAA	P02489	CRYGC	Homo sapiens	P07315	Y2H	12601044
Intra	CRYAA	P02489	CRYGC	Homo sapiens	P07315	Experimental Interac	11700327
Intra	CRYAA	P02489	CRYGC	Homo sapiens	P07315	Y2H	11700327
Intra	CRYAA	P02489	CRYAA	Homo sapiens	P02489	GMS	19651604
Intra	CRYAA	P02489	CRYAB	Homo sapiens	P02511	GMS	22085609
Intra	CRYAA	P02489	CRYAB	Homo sapiens	P02511	Solution Sedimentation	19651604
Intra	CRYAA	P02489	CRYAB	Homo sapiens	P02511	DLS	19651604
Intra	CRYAA	P02489	CRYAB	Homo sapiens	P02511	TEM	19651604
Intra	CRYAA	P02489	CRYAA	Homo sapiens	P02489	Y2H	12601044
Intra	CRYAA	P02489	CRYAA	Homo sapiens	P02489	Anti Bait CoIP	12601044
Intra	CRYAA	P02489	CRYAB	Homo sapiens	P02511	Validated Y2H	32296183
Intra	CRYAA	P02489	CRYAA	Homo sapiens	P02489	DLS	19651604
Intra	CRYAA	P02489	CRYAB	Homo sapiens	P02511	CoIP	11700327
Intra	CRYAA	P02489	CRYAB	Homo sapiens	P02511	Y2H	12601044
Intra	CRYAA	P02489	CRYAB	Homo sapiens	P02511	GMS	19651604
Intra	CRYAA	P02489	CRYAB	Homo sapiens	P02511	Anti Bait CoIP	12601044
Intra	CRYAA	P02489	RXRG	Homo sapiens	P48443	Validated Y2H	32814053
Intra	CRYAA	P02489	RXRG	Homo sapiens	P48443	Y2H Array	32814053
Intra	CRYAA	P02489	RXRG	Homo sapiens	P48443	Y2H Pooling	32814053
Intra	CRYAA	P02489	HMG20B	Homo sapiens	Q9P0W2	Validated Y2H	32814053
Intra	CRYAA	P02489	HMG20B	Homo sapiens	Q9P0W2	Y2H Pooling	32814053
Intra	CRYAA	P02489	HMG20B	Homo sapiens	Q9P0W2	Y2H Array	32814053
Intra	CRYAA	P02489	HMG20B	Homo sapiens	Q9P0W2	Anti Tag CoIP	33961781
Intra	CRYAA	P02489	STX11	Homo sapiens	O75558	Y2H Array	32814053
Intra	CRYAA	P02489	STX11	Homo sapiens	O75558	Validated Y2H	32814053
Intra	CRYAA	P02489	STX11	Homo sapiens	O75558	Y2H Pooling	32814053
Intra	CRYAA	P02489	KLHL20	Homo sapiens	Q9Y2M5	Y2H Pooling	32814053
Intra	CRYAA	P02489	KLHL20	Homo sapiens	Q9Y2M5	Validated Y2H	32814053
Intra	CRYAA	P02489	KLHL20	Homo sapiens	Q9Y2M5	Y2H Array	32814053
Intra	CRYAA	P02489	SDCBP	Homo sapiens	O00560	Y2H Array	31515488
Intra	CRYAA	P02489	SDCBP	Homo sapiens	O00560	Validated Y2H	25416956
Intra	CRYAA	P02489	GORASP2	Homo sapiens	Q9H8Y8	Validated Y2H	32296183
Intra	CRYAA	P02489	GORASP2	Homo sapiens	Q9H8Y8	Y2H Array	32296183
Intra	CRYAA	P02489	GORASP2	Homo sapiens	Q9H8Y8	Y2H Array	29892012
Intra	CRYAA	P02489	GORASP2	Homo sapiens	Q9H8Y8	Y2H Array	31515488
Intra	CRYAA	P02489	GORASP2	Homo sapiens	Q9H8Y8	Y2H Prey Pooling	25416956
Intra	CRYAA	P02489	GORASP2	Homo sapiens	Q9H8Y8	Y2H Prey Pooling	32296183
Intra	CRYAA	P02489	KRT81	Homo sapiens	Q14533	Validated Y2H	32814053
Intra	CRYAA	P02489	KRT81	Homo sapiens	Q14533	Y2H Pooling	32814053
Intra	CRYAA	P02489	KRT81	Homo sapiens	Q14533	Y2H Array	32814053
Intra	CRYAA	P02489	TSACC	Homo sapiens	Q96A04	Validated Y2H	32814053
Intra	CRYAA	P02489	TSACC	Homo sapiens	Q96A04	Y2H Array	32814053
Intra	CRYAA	P02489	TSACC	Homo sapiens	Q96A04	Y2H Pooling	32814053
Intra	CRYAA	P02489	NTAQ1	Homo sapiens	Q96HA8	Validated Y2H	32296183
Intra	CRYAA	P02489	NTAQ1	Homo sapiens	Q96HA8	Validated Y2H	25416956
Intra	CRYAA	P02489	NTAQ1	Homo sapiens	Q96HA8	Y2H Array	31515488
Intra	CRYAA	P02489	NTAQ1	Homo sapiens	Q96HA8	Y2H Prey Pooling	25416956
Intra	CRYAA	P02489	SPG21	Homo sapiens	Q9NZD8	Y2H Array	31515488
Intra	CRYAA	P02489	SPG21	Homo sapiens	Q9NZD8	Validated Y2H	32296183
Intra	CRYAA	P02489	SPG21	Homo sapiens	Q9NZD8	Y2H Array	25416956
Intra	CRYAA	P02489	BAHD1	Homo sapiens	Q8TBE0	Validated Y2H	32814053
Intra	CRYAA	P02489	BAHD1	Homo sapiens	Q8TBE0	Y2H Pooling	32814053
Intra	CRYAA	P02489	BAHD1	Homo sapiens	Q8TBE0	Y2H Array	32814053
Intra	CRYAA	P02489	BAG3	Homo sapiens	O95817	Anti Tag CoIP	33961781
Intra	CRYAA	P02489	BAG3	Homo sapiens	O95817	Validated Y2H	32814053
Intra	CRYAA	P02489	BAG3	Homo sapiens	O95817	Y2H Array	32814053
Intra	CRYAA	P02489	BAG3	Homo sapiens	O95817	Y2H Pooling	32814053
Intra	CRYAA	P02489	PRPS1	Homo sapiens	P60891	Y2H Pooling	32814053
Intra	CRYAA	P02489	PRPS1	Homo sapiens	P60891	Validated Y2H	32814053
Intra	CRYAA	P02489	PRPS1	Homo sapiens	P60891	Y2H Array	32814053
Intra	CRYAA	P02489	LOXL4	Homo sapiens	Q96JB6	Y2H Array	32814053
Intra	CRYAA	P02489	LOXL4	Homo sapiens	Q96JB6	Validated Y2H	32814053
Intra	CRYAA	P02489	LOXL4	Homo sapiens	Q96JB6	Y2H Pooling	32814053
Intra	CRYAA	P02489	SPATA46	Homo sapiens	Q5T0L3	Validated Y2H	32814053
Intra	CRYAA	P02489	SPATA46	Homo sapiens	Q5T0L3	Y2H Array	32814053
Intra	CRYAA	P02489	SPATA46	Homo sapiens	Q5T0L3	Y2H Pooling	32814053
Intra	CRYAA	P02489	TENT5B	Homo sapiens	Q96A09	Validated Y2H	32814053
Intra	CRYAA	P02489	TENT5B	Homo sapiens	Q96A09	Y2H Array	32814053
Intra	CRYAA	P02489	TENT5B	Homo sapiens	Q96A09	Y2H Pooling	32814053
Intra	CRYAA	P02489	PRPH	Homo sapiens	P41219	Validated Y2H	32814053
Intra	CRYAA	P02489	PRPH	Homo sapiens	P41219	Y2H Pooling	32814053
Intra	CRYAA	P02489	PRPH	Homo sapiens	P41219	Y2H Array	32814053
Intra	CRYAA	P02489	RYBP	Homo sapiens	Q8N488	Y2H Pooling	32814053
Intra	CRYAA	P02489	RYBP	Homo sapiens	Q8N488	Validated Y2H	32814053
Intra	CRYAA	P02489	RYBP	Homo sapiens	Q8N488	Y2H Array	32814053
Intra	CRYAA	P02489	KLF3	Homo sapiens	P57682	Validated Y2H	32814053
Intra	CRYAA	P02489	KLF3	Homo sapiens	P57682	Y2H Array	32814053
Intra	CRYAA	P02489	KLF3	Homo sapiens	P57682	Y2H Pooling	32814053
Intra	CRYAA	P02489	GFOD1	Homo sapiens	Q9NXC2	Y2H Pooling	32814053
Intra	CRYAA	P02489	GFOD1	Homo sapiens	Q9NXC2	Validated Y2H	32814053
Intra	CRYAA	P02489	GFOD1	Homo sapiens	Q9NXC2	Y2H Array	32814053
Intra	CRYAA	P02489	ZNF296	Homo sapiens	Q8WUU4	Y2H Pooling	32814053
Intra	CRYAA	P02489	ZNF296	Homo sapiens	Q8WUU4	Validated Y2H	32814053
Intra	CRYAA	P02489	ZNF296	Homo sapiens	Q8WUU4	Y2H Array	32814053
Intra	CRYAA	P02489	LASP1	Homo sapiens	Q14847-2	Y2H Pooling	32814053
Intra	CRYAA	P02489	LASP1	Homo sapiens	Q14847-2	Validated Y2H	32814053
Intra	CRYAA	P02489	LASP1	Homo sapiens	Q14847-2	Y2H Array	32814053
Intra	CRYAA	P02489	TUT7	Homo sapiens	Q5VYS8-5	Validated Y2H	32814053
Intra	CRYAA	P02489	TUT7	Homo sapiens	Q5VYS8-5	Y2H Pooling	32814053
Intra	CRYAA	P02489	TUT7	Homo sapiens	Q5VYS8-5	Y2H Array	32814053
Intra	CRYAA	P02489	LGALS9C	Homo sapiens	Q6DKI2	Y2H Array	32814053
Intra	CRYAA	P02489	LGALS9C	Homo sapiens	Q6DKI2	Validated Y2H	32814053
Intra	CRYAA	P02489	LGALS9C	Homo sapiens	Q6DKI2	Y2H Pooling	32814053
Intra	CRYAA	P02489	TMTC1	Homo sapiens	Q8IUR5-4	Y2H Array	32814053
Intra	CRYAA	P02489	TMTC1	Homo sapiens	Q8IUR5-4	Validated Y2H	32814053
Intra	CRYAA	P02489	TMTC1	Homo sapiens	Q8IUR5-4	Y2H Pooling	32814053
Intra	CRYAA	P02489	SEMA4G	Homo sapiens	Q9NTN9-3	Y2H Pooling	32814053
Intra	CRYAA	P02489	SEMA4G	Homo sapiens	Q9NTN9-3	Validated Y2H	32814053
Intra	CRYAA	P02489	SEMA4G	Homo sapiens	Q9NTN9-3	Y2H Array	32814053
Intra	CRYAA	P02489	GATA1	Homo sapiens	P15976-2	Validated Y2H	32814053
Intra	CRYAA	P02489	GATA1	Homo sapiens	P15976-2	Y2H Array	32814053
Intra	CRYAA	P02489	GATA1	Homo sapiens	P15976-2	Y2H Pooling	32814053
Intra	CRYAA	P02489	BAIAP2	Homo sapiens	Q9UQB8-6	Y2H Pooling	32814053
Intra	CRYAA	P02489	BAIAP2	Homo sapiens	Q9UQB8-6	Validated Y2H	32814053
Intra	CRYAA	P02489	BAIAP2	Homo sapiens	Q9UQB8-6	Y2H Array	32814053
Intra	CRYAA	P02489	TCAP	Homo sapiens	O15273	Validated Y2H	32814053
Intra	CRYAA	P02489	TCAP	Homo sapiens	O15273	Y2H Array	32814053
Intra	CRYAA	P02489	TCAP	Homo sapiens	O15273	Y2H Pooling	32814053
Intra	CRYAA	P02489	EIF4B	Homo sapiens	P23588	Validated Y2H	32814053
Intra	CRYAA	P02489	EIF4B	Homo sapiens	P23588	Y2H Pooling	32814053
Intra	CRYAA	P02489	EIF4B	Homo sapiens	P23588	Y2H Array	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant HAPLN1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76379	HAPLN1 Protein, Human (HEK293, His)	P10915 (D16-N354)	≥95%

Related Diseases

Diseases

Alias

Juvenile Rheumatoid Arthritis

Juvenile Idiopathic Arthritis	Juvenile Chronic Polyarthritis
Monarticular Juvenile Rheumatoid Arthritis	Pauciarticular Juvenile Arthritis
Still'S Disease	Systemic Juvenile Rheumatoid Arthritis
Juvenile Chronic Arthritis	Acute Juvenile Rheumatoid Arthritis
Pauciarticular Onset Juvenile Chronic Arthritis	Arthritis, Juvenile Rheumatoid
Jia	Jra
Juvenile Ra	Arthritis Juvenile Rheumatoid
Stills Disease	Juvenile Arthritis
Acute Polyarticular Juvenile Rheumatoid Arthritis	Pauciarticular Juvenile Rheumatoid Arthritis
Rheumatoid Arthritis, Systemic Juvenile

Cerebral Creatine Deficiency Syndrome

Deficiency, Cerebral Creatine, Syndrome

Cerebral Creatine Deficiency Syndrome 1

Creatine Transporter Deficiency	Creatine Transporter Defect
Slc6a8 Deficiency	X-Linked Creatine Deficiency Syndrome
CCDS1	Creatine Deficiency Syndrome, X-Linked
X-Linked Creatine Deficiency	Creatine Deficiency, X-Linked
X-Linked Creatine Transporter Deficiency	Mental Retardation, X-Linked, With Seizures, Short Stature, And Midface Hypoplasia
Mental Retardation, X-Linked, With Creatine Transport Deficiency	Intellectual Disability, X-Linked With Seizures, Short Stature And Midface Hypoplasia
Intellectual Disability, X-Linked, With Creatine Transport Deficiency	Slc6a8-Related Creatine Transporter Deficiency
Deficiency, Cerebral Creatine, Syndrome, Type 1

Pseudoachondroplasia

PSACH	Pseudoachondroplastic Dysplasia
Pseudoachondroplastic Spondyloepiphyseal Dysplasia Syndrome	Spondyloepiphyseal Dysplasia, Pseudoachondroplastic
Pseudoachondroplastic Spondyloepiphyseal Dysplasia	Spondyloepiphyseal Dysplasia Pseudoachondroplastic

Osteoarthritis

Osteoarthrosis	Degenerative Joint Disease
Hypertrophic Arthritis	Arthropathy
Degenerative Polyarthritis	Degenerative Arthritis
Osteoarthrosis And Allied Disorder	Arthritis, Degenerative
Oa	Osteoarthritis Deformans
Osteoarthrosis Deformans	Kashin-Beck Disease

Cerebral Creatine Deficiency Syndrome 3

Arginine:Glycine Amidinotransferase Deficiency	Agat Deficiency
Gatm Deficiency	Creatine Deficiency Syndrome Due To Agat Deficiency
L-Arginine:Glycine Amidinotransferase Deficiency	CCDS3
L-Arginine:Glycine Aminidotransferase Deficiency	Deficiency, Cerebral Creatine, Syndrome, Type 3

Depersonalization Disorder

Neurotic Derealization	Depersonalization
Depersonalization/Derealization Disorder	Depersonalisation-Derealization Syndrome
Depersonalisation Disorder	Depersonalisation Neurosis
Depersonalisation Syndrome	Feeling Of Unreality
Feels Own Self Is Unreal	Neurotic State With Depersonalisation
Neurotic State With Depersonalization Episode

Cerebral Creatine Deficiency Syndrome 2

Guanidinoacetate Methyltransferase Deficiency	Gamt Deficiency
Creatine Deficiency Syndrome Due To Gamt Deficiency	Deficiency Of Guanidinoacetate Methyltransferase
CCDS2	Guanidinoacetate Methyltransferase Deficiency
Deficiency, Cerebral Creatine, Syndrome, Type 2	Language Development Disorders

Sleep Disorder

Sleep Disorders

Non-Organic Sleep Disorder

Von Economo'S Disease

Encephalitis Lethargica	Von Economo Encephalitis
Von Economo Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06001	HAPLN1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	HAPLN1	VGNC	VGNC:73220
Mus musculus	HAPLN1	MGD	MGI:1337006
Bos taurus	HAPLN1	VGNC	VGNC:29749
Canis familiaris	HAPLN1	VGNC	VGNC:41593
Felis catus	HAPLN1	VGNC	VGNC:102221
Rattus norvegicus	HAPLN1	RGD	RGD:2412
Others	HAPLN1	NCBI

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