SGTA - small glutamine rich tetratricopeptide repeat co-chaperone alpha Gene

Homo sapiens

Also known as SGT; Vpu; SGT1; hSGT; alphaSGT

Gene ID: 6449 | Gene type: protein coding

About SGTA

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:2,754,715-2,783,273 (from NCBI)

This gene has 18 transcripts (splice variants), 209 orthologues and 18 paralogues. Ubiquitous expression in testis (RPKM 22.5), brain (RPKM 21.2) and 25 other tissues.

Summary

This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function. [provided by RefSeq, Jul 2008]

SGTA Products(1)

mRNA	Protein	Name
NM_003021.4	NP_003012.1	small glutamine-rich tetratricopeptide repeat-containing protein alpha

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables BAT3 complex binding	IPI IPI: Inferred from physical interaction	23246001	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	25036637	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	14667819	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in ERAD pathway	IDA IDA: Inferred from direct assay	23129660	GOA
involved in negative regulation of ERAD pathway	IDA IDA: Inferred from direct assay	23129660	GOA
involved in negative regulation of ubiquitin-dependent protein catabolic process	IDA IDA: Inferred from direct assay	23129660	GOA
involved in positive regulation of ERAD pathway	IMP IMP: Inferred from mutant phenotype	23246001	GOA
involved in positive regulation of ubiquitin-dependent protein catabolic process	IMP IMP: Inferred from mutant phenotype	23246001	GOA
involved in tail-anchored membrane protein insertion into ER membrane	IDA IDA: Inferred from direct assay	25535373	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	16580629	GOA
located in cytosol	IDA IDA: Inferred from direct assay	23246001	GOA
located in membrane	IDA IDA: Inferred from direct assay	23246001	GOA
located in nucleus	IDA IDA: Inferred from direct assay	16580629	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SGTA Protein Structure

TPR_11

TPR_1

0
100
200
313 a.a.

Protein Preferred Names

Protein Names

small glutamine-rich tetratricopeptide repeat-containing protein alpha

UBP

SGTA Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	SGTA	O43765	ADIPOQ	Homo sapiens	A8K660	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	GYPA	Homo sapiens	B8Q183	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	GYPA	Homo sapiens	B8Q183	Validated Y2H	25416956
Intra	SGTA	O43765	GYPA	Homo sapiens	B8Q183	Y2H Array	25416956
Intra	SGTA	O43765	FERD3L	Homo sapiens	Q96RJ6	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	UPK3A	Homo sapiens	O75631	Y2H Array	25416956
Intra	SGTA	O43765	MSMB	Homo sapiens	P08118	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	MSMB	Homo sapiens	P08118	Validated Y2H	25416956
Intra	SGTA	O43765	SOD3	Homo sapiens	P08294	Y2H Array	25416956
Intra	SGTA	O43765	SOD3	Homo sapiens	P08294	Validated Y2H	25416956
Intra	SGTA	O43765	CDH15	Homo sapiens	P55291	Validated Y2H	25416956
Intra	SGTA	O43765	CDH15	Homo sapiens	P55291	Validated Y2H	32296183
Intra	SGTA	O43765	CDH15	Homo sapiens	P55291	Y2H Array	25416956
Intra	SGTA	O43765	CDH15	Homo sapiens	P55291	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	FXYD7	Homo sapiens	P58549	Validated Y2H	32296183
Intra	SGTA	O43765	FXYD7	Homo sapiens	P58549	Y2H Array	25416956
Intra	SGTA	O43765	FXYD7	Homo sapiens	P58549	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	TFF3	Homo sapiens	Q07654	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	TFF3	Homo sapiens	Q07654	Validated Y2H	25416956
Intra	SGTA	O43765	SMAGP	Homo sapiens	Q0VAQ4	Validated Y2H	25416956
Intra	SGTA	O43765	SMAGP	Homo sapiens	Q0VAQ4	Y2H Array	25416956
Intra	SGTA	O43765	GPErik	Homo sapiens	Q14440	Validated Y2H	25416956
Intra	SGTA	O43765	TTMP	Homo sapiens	Q5BVD1	Validated Y2H	32296183
Intra	SGTA	O43765	TTMP	Homo sapiens	Q5BVD1	Validated Y2H	25416956
Intra	SGTA	O43765	TTMP	Homo sapiens	Q5BVD1	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	PAGE3	Homo sapiens	Q5JUK9	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	PAGE3	Homo sapiens	Q5JUK9	Validated Y2H	32296183
Intra	SGTA	O43765	PAGE3	Homo sapiens	Q5JUK9	Y2H Array	32296183
Intra	SGTA	O43765	TMEM31	Homo sapiens	Q5JXX7	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	TMEM31	Homo sapiens	Q5JXX7	Validated Y2H	25416956
Intra	SGTA	O43765	LAIR2	Homo sapiens	Q6ISS4	Validated Y2H	32296183
Intra	SGTA	O43765	LAIR2	Homo sapiens	Q6ISS4	Validated Y2H	25416956
Intra	SGTA	O43765	LSMEM2	Homo sapiens	Q8N112	Validated Y2H	32296183
Intra	SGTA	O43765	LSMEM2	Homo sapiens	Q8N112	Y2H Array	32296183
Intra	SGTA	O43765	LSMEM2	Homo sapiens	Q8N112	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	PRRG2	Homo sapiens	Q8TAS3	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	PRRG2	Homo sapiens	Q8TAS3	Y2H Array	32296183
Intra	SGTA	O43765	PRRG2	Homo sapiens	Q8TAS3	Validated Y2H	32296183
Intra	SGTA	O43765	TMEM174	Homo sapiens	Q8WUU8	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	TMEM174	Homo sapiens	Q8WUU8	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	TMEM174	Homo sapiens	Q8WUU8	Validated Y2H	32296183
Intra	SGTA	O43765	TMEM174	Homo sapiens	Q8WUU8	Y2H Array	32296183
Intra	SGTA	O43765	C1QTNF6	Homo sapiens	Q9BXI9	Y2H Array	25416956
Intra	SGTA	O43765	C1QTNF6	Homo sapiens	Q9BXI9	Y2H Array	32296183
Intra	SGTA	O43765	C1QTNF6	Homo sapiens	Q9BXI9	Validated Y2H	32296183
Intra	SGTA	O43765	C1QTNF6	Homo sapiens	Q9BXI9	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	C1QTNF6	Homo sapiens	Q9BXI9	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	TWSG1	Homo sapiens	Q9GZX9	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	TWSG1	Homo sapiens	Q9GZX9	Y2H Array	25416956
Intra	SGTA	O43765	IL6ST	Homo sapiens	P40189	Validated Y2H	32296183
Intra	SGTA	O43765	EVA1B	Homo sapiens	Q9NVM1	Validated Y2H	25416956
Intra	SGTA	O43765	EVA1B	Homo sapiens	Q9NVM1	Validated Y2H	32296183
Intra	SGTA	O43765	PLAAT4	Homo sapiens	Q9UL19	Y2H Array	25416956
Intra	SGTA	O43765	PLAAT4	Homo sapiens	Q9UL19	Y2H Array	31515488
Intra	SGTA	O43765	TGFA	Homo sapiens	P01135	Y2H Array	25416956
Intra	SGTA	O43765	CST1	Homo sapiens	P01037	Y2H Array	25416956
Intra	SGTA	O43765	CST1	Homo sapiens	P01037	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	CST1	Homo sapiens	P01037	Validated Y2H	25416956
Intra	SGTA	O43765	ADIPOQ	Homo sapiens	Q15848	Y2H Array	31515488
Intra	SGTA	O43765	ADIPOQ	Homo sapiens	Q15848	Validated Y2H	32296183
Intra	SGTA	O43765	BAG6	Homo sapiens	P46379-2	Validated Y2H	32296183
Intra	SGTA	O43765	MYOC	Homo sapiens	Q99972	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	MYOC	Homo sapiens	Q99972	Validated Y2H	32296183
Intra	SGTA	O43765	MYOC	Homo sapiens	Q99972	Y2H Array	32296183
Intra	SGTA	O43765	CTAG1A	Homo sapiens	P78358	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	CTAG1A	Homo sapiens	P78358	Validated Y2H	32296183
Intra	SGTA	O43765	CTAG1A	Homo sapiens	P78358	Y2H Array	32296183
Intra	SGTA	O43765	LCN2	Homo sapiens	P80188	Validated Y2H	32296183
Intra	SGTA	O43765	WFDC12	Homo sapiens	Q8WWY7	Validated Y2H	32296183
Intra	SGTA	O43765	PSORS1C2	Homo sapiens	Q9UIG4	Validated Y2H	32296183
Intra	SGTA	O43765	CHRNG	Homo sapiens	P07510-2	Validated Y2H	32296183
Intra	SGTA	O43765	KCNE5	Homo sapiens	Q9UJ90	Validated Y2H	32296183
Intra	SGTA	O43765	C5orf46	Homo sapiens	Q6UWT4	Validated Y2H	32296183
Intra	SGTA	O43765	KTN1	Homo sapiens	Q86UP2-3	Validated Y2H	32296183
Intra	SGTA	O43765	WFDC13	Homo sapiens	Q8IUB5	Validated Y2H	32296183
Intra	SGTA	O43765	ADAM21	Homo sapiens	Q9UKJ8	Validated Y2H	32296183
Intra	SGTA	O43765	RNF170	Homo sapiens	Q96K19-5	Validated Y2H	32296183
Intra	SGTA	O43765	C1QL4	Homo sapiens	Q86Z23	Validated Y2H	32296183
Intra	SGTA	O43765	TNFRSF19	Homo sapiens	Q9NS68-2	Validated Y2H	32296183
Intra	SGTA	O43765	WFDC5	Homo sapiens	Q8TCV5	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	WFDC5	Homo sapiens	Q8TCV5	Validated Y2H	32296183
Intra	SGTA	O43765	WFDC5	Homo sapiens	Q8TCV5	Y2H Array	32296183
Intra	SGTA	O43765	CTSL	Homo sapiens	P07711	Validated Y2H	25416956
Intra	SGTA	O43765	LAT	Homo sapiens	O43561	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	GALP	Homo sapiens	Q9UBC7	Validated Y2H	32296183
Intra	SGTA	O43765	GUCA2A	Homo sapiens	Q02747	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	GUCA2A	Homo sapiens	Q02747	Y2H Array	32296183
Intra	SGTA	O43765	GUCA2A	Homo sapiens	Q02747	Validated Y2H	32296183
Intra	SGTA	O43765	KCNA10	Homo sapiens	Q16322	Validated Y2H	32296183
Intra	SGTA	O43765	KCNA10	Homo sapiens	Q16322	Y2H Array	32296183
Intra	SGTA	O43765	KCNA10	Homo sapiens	Q16322	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	SRL	Homo sapiens	Q86TD4-2	Validated Y2H	32296183
Intra	SGTA	O43765	DEFB131A	Homo sapiens	P59861	Validated Y2H	32296183
Intra	SGTA	O43765	SMIM5	Homo sapiens	Q71RC9	Validated Y2H	32296183
Intra	SGTA	O43765	SMIM5	Homo sapiens	Q71RC9	Complementation	32296183
Intra	SGTA	O43765	SMIM5	Homo sapiens	Q71RC9	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	SMIM5	Homo sapiens	Q71RC9	Y2H Array	32296183
Intra	SGTA	O43765	ITPRIPL1	Homo sapiens	Q6GPH6-2	Validated Y2H	32296183
Intra	SGTA	O43765	TGFA	Homo sapiens	P01135-2	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	TGFA	Homo sapiens	P01135-2	Y2H Array	32296183
Intra	SGTA	O43765	TGFA	Homo sapiens	P01135-2	Validated Y2H	32296183
Intra	SGTA	O43765	RNASE10	Homo sapiens	Q5GAN6	Validated Y2H	32296183
Intra	SGTA	O43765	PGLYRP2	Homo sapiens	Q96PD5-2	Validated Y2H	32296183
Intra	SGTA	O43765	MS4A3	Homo sapiens	Q96HJ5	Validated Y2H	32296183
Intra	SGTA	O43765	MS4A3	Homo sapiens	Q96HJ5	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	MS4A3	Homo sapiens	Q96HJ5	Y2H Array	32296183
Intra	SGTA	O43765	TRIM5	Homo sapiens	Q9C035-3	Y2H Array	32296183
Intra	SGTA	O43765	TRIM5	Homo sapiens	Q9C035-3	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	TRIM5	Homo sapiens	Q9C035-3	Validated Y2H	32296183
Intra	SGTA	O43765	PCDHGA4	Homo sapiens	Q9Y5G9	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	PCDHGA4	Homo sapiens	Q9Y5G9	Validated Y2H	32296183
Intra	SGTA	O43765	PCDHGA4	Homo sapiens	Q9Y5G9	Y2H Array	32296183
Intra	SGTA	O43765	EDAR	Homo sapiens	Q9UNE0-2	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	EDAR	Homo sapiens	Q9UNE0-2	Y2H Array	32296183
Intra	SGTA	O43765	EDAR	Homo sapiens	Q9UNE0-2	Validated Y2H	32296183
Intra	SGTA	O43765	FXYD2	Homo sapiens	P54710-2	Validated Y2H	32296183
Intra	SGTA	O43765	SPINK9	Homo sapiens	Q5DT21	Validated Y2H	32296183
Intra	SGTA	O43765	LDLRAD4	Homo sapiens	O15165-2	Y2H Array	32296183
Intra	SGTA	O43765	LDLRAD4	Homo sapiens	O15165-2	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	PMEPA1	Homo sapiens	Q969W9-2	Validated Y2H	32296183
Intra	SGTA	O43765	PMEPA1	Homo sapiens	Q969W9-2	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	PMEPA1	Homo sapiens	Q969W9-2	Y2H Array	32296183
Intra	SGTA	O43765	TMEM154	Homo sapiens	Q6P9G4	Validated Y2H	32296183
Intra	SGTA	O43765	TMEM154	Homo sapiens	Q6P9G4	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	TMEM154	Homo sapiens	Q6P9G4	Y2H Array	32296183
Intra	SGTA	O43765	SHISA5	Homo sapiens	Q8N114-3	Y2H Array	32296183
Intra	SGTA	O43765	SHISA5	Homo sapiens	Q8N114-3	Validated Y2H	32296183
Intra	SGTA	O43765	SHISA5	Homo sapiens	Q8N114-3	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	a0a1u9x8x8_human	Homo sapiens	A0A1U9X8X8	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	a0a1u9x8x8_human	Homo sapiens	A0A1U9X8X8	Y2H Array	32296183
Intra	SGTA	O43765	IER3	Homo sapiens	P46695	Y2H Array	32296183
Intra	SGTA	O43765	IER3	Homo sapiens	P46695	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	IER3	Homo sapiens	P46695	Validated Y2H	32296183
Intra	SGTA	O43765	ZBTB8B	Homo sapiens	Q8NAP8	Y2H Array	32296183
Intra	SGTA	O43765	ZBTB8B	Homo sapiens	Q8NAP8	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	ZBTB8B	Homo sapiens	Q8NAP8	Validated Y2H	32296183
Intra	SGTA	O43765	NPVF	Homo sapiens	Q9HCQ7	Validated Y2H	32296183
Intra	SGTA	O43765	TMEM230	Homo sapiens	Q96A57-2	Validated Y2H	32296183
Intra	SGTA	O43765	SHISA4	Homo sapiens	Q96DD7	Validated Y2H	32296183
Intra	SGTA	O43765	SHISA4	Homo sapiens	Q96DD7	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	SHISA4	Homo sapiens	Q96DD7	Y2H Array	32296183
Intra	SGTA	O43765	STMP1	Homo sapiens	E0CX11	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	STMP1	Homo sapiens	E0CX11	Y2H Array	32296183
Intra	SGTA	O43765	C1QTNF5	Homo sapiens	Q9BXJ0	Validated Y2H	32296183
Intra	SGTA	O43765	C1QTNF5	Homo sapiens	Q9BXJ0	Y2H Array	32296183
Intra	SGTA	O43765	C1QTNF5	Homo sapiens	Q9BXJ0	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	PRAP1	Homo sapiens	Q96NZ9	Validated Y2H	25416956
Intra	SGTA	O43765	PRAP1	Homo sapiens	Q96NZ9	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	PRAP1	Homo sapiens	Q96NZ9	Validated Y2H	32296183
Intra	SGTA	O43765	PRAP1	Homo sapiens	Q96NZ9	Y2H Array	25416956
Intra	SGTA	O43765	PRAP1	Homo sapiens	Q96NZ9	Y2H Array	32296183
Intra	SGTA	O43765	TNFRSF21	Homo sapiens	O75509	Validated Y2H	32296183
Intra	SGTA	O43765	SDF2L1	Homo sapiens	Q9HCN8	Validated Y2H	32296183
Intra	SGTA	O43765	RNF144A	Homo sapiens	P50876	Validated Y2H	32296183
Intra	SGTA	O43765	RNF144A	Homo sapiens	P50876	Y2H Array	32296183
Intra	SGTA	O43765	RNF144A	Homo sapiens	P50876	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	FSTL1	Homo sapiens	Q12841	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	FSTL1	Homo sapiens	Q12841	Validated Y2H	32296183
Intra	SGTA	O43765	TXNDC12	Homo sapiens	O95881	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	TXNDC12	Homo sapiens	O95881	Validated Y2H	25416956
Intra	SGTA	O43765	TXNDC12	Homo sapiens	O95881	Y2H Array	25416956
Intra	SGTA	O43765	IRF3	Homo sapiens	Q14653	Anti Tag CoIP	21988832
Intra	SGTA	O43765	IRF3	Homo sapiens	Q14653	Confocal	21988832
Intra	SGTA	O43765	TMUB2	Homo sapiens	Q71RG4	Y2H Array	25416956
Intra	SGTA	O43765	TMUB2	Homo sapiens	Q71RG4	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	CD99L2	Homo sapiens	Q8TCZ2	Validated Y2H	32296183
Intra	SGTA	O43765	ETNK1	Homo sapiens	Q9HBU6	Validated Y2H	32296183
Intra	SGTA	O43765	CSF1	Homo sapiens	P09603	Y2H Array	25416956
Intra	SGTA	O43765	CSF1	Homo sapiens	P09603	Validated Y2H	32296183
Intra	SGTA	O43765	CSF1	Homo sapiens	P09603	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	CD79B	Homo sapiens	P40259	Validated Y2H	25416956
Intra	SGTA	O43765	CD79B	Homo sapiens	P40259	Y2H Array	25416956
Intra	SGTA	O43765	BAG6	Homo sapiens	P46379	Y2H Array	25416956
Intra	SGTA	O43765	BAG6	Homo sapiens	P46379	Validated Y2H	25416956
Intra	SGTA	O43765	BAG6	Homo sapiens	P46379	Anti Tag CoIP	25036637
Intra	SGTA	O43765	BAG6	Homo sapiens	P46379	Y2H Array	31515488
Intra	SGTA	O43765	EFEMP1	Homo sapiens	Q12805	Validated Y2H	25416956
Intra	SGTA	O43765	EFEMP1	Homo sapiens	Q12805	Validated Y2H	32296183
Intra	SGTA	O43765	EFEMP1	Homo sapiens	Q12805	Y2H Array	25416956
Intra	SGTA	O43765	EFEMP1	Homo sapiens	Q12805	Y2H Array	31515488
Intra	SGTA	O43765	SGCA	Homo sapiens	Q16586	Y2H Array	25416956
Intra	SGTA	O43765	BAG2	Homo sapiens	O95816	Anti Tag CoIP	25036637
Intra	SGTA	O43765	SLPI	Homo sapiens	P03973	Validated Y2H	32296183
Intra	SGTA	O43765	SLPI	Homo sapiens	P03973	Y2H Array	32296183
Intra	SGTA	O43765	SLPI	Homo sapiens	P03973	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	SLPI	Homo sapiens	P03973	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	TFRC	Homo sapiens	P02786	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	TFRC	Homo sapiens	P02786	Validated Y2H	25416956
Intra	SGTA	O43765	TFRC	Homo sapiens	P02786	Validated Y2H	32296183
Intra	SGTA	O43765	RPN1	Homo sapiens	P04843	Y2H Array	31515488
Intra	SGTA	O43765	RPN1	Homo sapiens	P04843	Validated Y2H	25416956
Intra	SGTA	O43765	RPN1	Homo sapiens	P04843	Validated Y2H	32296183
Intra	SGTA	O43765	RPN1	Homo sapiens	P04843	Y2H Array	25416956
Intra	SGTA	O43765	UBL4A	Homo sapiens	P11441	Anti Tag CoIP	25036637
Intra	SGTA	O43765	UBL4A	Homo sapiens	P11441	Validated Y2H	32296183
Intra	SGTA	O43765	PPIB	Homo sapiens	P23284	Validated Y2H	32296183
Intra	SGTA	O43765	PPIB	Homo sapiens	P23284	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	PPIB	Homo sapiens	P23284	Y2H Array	25416956
Intra	SGTA	O43765	KTN1	Homo sapiens	Q86UP2	Validated Y2H	25416956
Intra	SGTA	O43765	KTN1	Homo sapiens	Q86UP2	Y2H Array	25416956
Intra	SGTA	O43765	SMIM14	Homo sapiens	Q96QK8	Validated Y2H	32296183
Intra	SGTA	O43765	FGF21	Homo sapiens	Q9NSA1	Validated Y2H	32296183
Intra	SGTA	O43765	SDC4	Homo sapiens	P31431	Validated Y2H	32296183
Intra	SGTA	O43765	FKBP7	Homo sapiens	Q9Y680	Validated Y2H	25416956
Intra	SGTA	O43765	FKBP7	Homo sapiens	Q9Y680	Validated Y2H	32296183
Intra	SGTA	O43765	FKBP7	Homo sapiens	Q9Y680	Y2H Array	25416956
Intra	SGTA	O43765	SUOX	Homo sapiens	P51687	Validated Y2H	32296183
Intra	SGTA	O43765	AOC3	Homo sapiens	Q16853	Validated Y2H	32296183
Intra	SGTA	O43765	AGR3	Homo sapiens	Q8TD06	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	AGR3	Homo sapiens	Q8TD06	Validated Y2H	25416956
Intra	SGTA	O43765	AGR3	Homo sapiens	Q8TD06	Validated Y2H	32296183
Intra	SGTA	O43765	IRF5	Homo sapiens	Q13568	Y2H	21988832
Intra	SGTA	O43765	IRF5	Homo sapiens	Q13568	Anti Tag CoIP	21988832
Intra	SGTA	O43765	EDA2R	Homo sapiens	Q9HAV5	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	EDA2R	Homo sapiens	Q9HAV5	Validated Y2H	32296183
Intra	SGTA	O43765	EDA2R	Homo sapiens	Q9HAV5	Y2H Array	32296183
Intra	SGTA	O43765	SGCA	Homo sapiens	Q16586	Validated Y2H	25416956
Intra	SGTA	O43765	SGCA	Homo sapiens	Q16586	Validated Y2H	32296183
Intra	SGTA	O43765	BTC	Homo sapiens	P35070	Validated Y2H	32296183
Intra	SGTA	O43765	GAL	Homo sapiens	P22466	Validated Y2H	25416956
Intra	SGTA	O43765	GAL	Homo sapiens	P22466	Validated Y2H	32296183
Intra	SGTA	O43765	GAL	Homo sapiens	P22466	Y2H Array	25416956
Intra	SGTA	O43765	IGL@	Homo sapiens	Q6PIQ7	Y2H Array	25416956
Intra	SGTA	O43765	KRT6A	Homo sapiens	P02538	Y2H Array	25416956
Intra	SGTA	O43765	GYPA	Homo sapiens	P02724	Validated Y2H	32296183
Intra	SGTA	O43765	PCDHA4	Homo sapiens	Q9UN74	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	PCDHA4	Homo sapiens	Q9UN74	Y2H Array	25416956
Intra	SGTA	O43765	AGR2	Homo sapiens	O95994	Validated Y2H	32296183
Intra	SGTA	O43765	NME3	Homo sapiens	Q13232	Validated Y2H	32296183
Intra	SGTA	O43765	NME3	Homo sapiens	Q13232	Y2H Array	25416956
Intra	SGTA	O43765	NME3	Homo sapiens	Q13232	Y2H Array	32296183
Intra	SGTA	O43765	NME3	Homo sapiens	Q13232	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	MYDGF	Homo sapiens	Q969H8	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	MYDGF	Homo sapiens	Q969H8	Validated Y2H	32296183
Intra	SGTA	O43765	MYDGF	Homo sapiens	Q969H8	Y2H Array	25416956
Intra	SGTA	O43765	SPP1	Homo sapiens	P10451	Validated Y2H	25416956
Intra	SGTA	O43765	SPP1	Homo sapiens	P10451	Y2H Pooling	16189514
Intra	SGTA	O43765	NRSN2	Homo sapiens	Q9GZP1	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	NRSN2	Homo sapiens	Q9GZP1	Validated Y2H	32296183
Intra	SGTA	O43765	NRSN2	Homo sapiens	Q9GZP1	Y2H Array	32296183
Intra	SGTA	O43765	TMEM98	Homo sapiens	Q9Y2Y6	Validated Y2H	32296183
Intra	SGTA	O43765	PBXIP1	Homo sapiens	Q96AQ6	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	PBXIP1	Homo sapiens	Q96AQ6	Y2H Array	31515488
Intra	SGTA	O43765	PBXIP1	Homo sapiens	Q96AQ6	Validated Y2H	25416956
Intra	SGTA	O43765	PBXIP1	Homo sapiens	Q96AQ6	Y2H Array	25416956
Intra	SGTA	O43765	F11R	Homo sapiens	Q9Y624	Validated Y2H	32296183
Intra	SGTA	O43765	F11R	Homo sapiens	Q9Y624	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	F11R	Homo sapiens	Q9Y624	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	F11R	Homo sapiens	Q9Y624	Y2H Array	32296183
Intra	SGTA	O43765	F11R	Homo sapiens	Q9Y624	Y2H Array	25416956
Intra	SGTA	O43765	F11R	Homo sapiens	Q9Y624	Y2H Pooling	16189514
Intra	SGTA	O43765	EFEMP2	Homo sapiens	O95967	Y2H Pooling	16189514
Intra	SGTA	O43765	EFEMP2	Homo sapiens	O95967	Y2H Array	32296183
Intra	SGTA	O43765	EFEMP2	Homo sapiens	O95967	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	EFEMP2	Homo sapiens	O95967	Validated Y2H	32296183
Intra	SGTA	O43765	EFEMP2	Homo sapiens	O95967	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	SGTB	Homo sapiens	Q96EQ0	Y2H Array	32296183
Intra	SGTA	O43765	SGTB	Homo sapiens	Q96EQ0	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	SGTB	Homo sapiens	Q96EQ0	Validated Y2H	32296183
Intra	SGTA	O43765	SRGN	Homo sapiens	P10124	Validated Y2H	32296183
Intra	SGTA	O43765	SRGN	Homo sapiens	P10124	Y2H Array	32296183
Intra	SGTA	O43765	SRGN	Homo sapiens	P10124	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	SRGN	Homo sapiens	P10124	Validated Y2H	25416956
Intra	SGTA	O43765	SRGN	Homo sapiens	P10124	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	ZG16	Homo sapiens	O60844	Validated Y2H	32296183
Intra	SGTA	O43765	ZG16	Homo sapiens	O60844	Y2H Array	25416956
Intra	SGTA	O43765	ZG16	Homo sapiens	O60844	Y2H Array	32296183
Intra	SGTA	O43765	ZG16	Homo sapiens	O60844	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	ZG16	Homo sapiens	O60844	Y2H Pooling	16189514
Intra	SGTA	O43765	ZG16	Homo sapiens	O60844	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	ZG16	Homo sapiens	O60844	Validated Y2H	25416956
Intra	SGTA	O43765	FZD7	Homo sapiens	O75084	Validated Y2H	32296183
Intra	SGTA	O43765	GRN	Homo sapiens	P28799	Y2H Array	31515488
Intra	SGTA	O43765	GRN	Homo sapiens	P28799	Validated Y2H	25416956
Intra	SGTA	O43765	IGL@	Homo sapiens	Q8N355	Validated Y2H	25416956
Intra	SGTA	O43765	IGL@	Homo sapiens	Q8N355	Y2H Array	25416956
Intra	SGTA	O43765	IGL@	Homo sapiens	Q8N355	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	KASH5	Homo sapiens	Q8N6L0	BFG-2H	27107012
Intra	SGTA	O43765	KASH5	Homo sapiens	Q8N6L0	Validated Y2H	25416956
Intra	SGTA	O43765	KASH5	Homo sapiens	Q8N6L0	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	KASH5	Homo sapiens	Q8N6L0	Validated Y2H	32296183
Intra	SGTA	O43765	KASH5	Homo sapiens	Q8N6L0	Y2H Array	25416956
Intra	SGTA	O43765	KASH5	Homo sapiens	Q8N6L0	Y2H Array	32296183
Intra	SGTA	O43765	GPX7	Homo sapiens	Q96SL4	Validated Y2H	32296183
Intra	SGTA	O43765	GPX7	Homo sapiens	Q96SL4	Complementation	32296183
Intra	SGTA	O43765	GPX7	Homo sapiens	Q96SL4	Y2H Array	32296183
Intra	SGTA	O43765	GPX7	Homo sapiens	Q96SL4	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	SERPINI2	Homo sapiens	O75830	Validated Y2H	32296183
Intra	SGTA	O43765	C1QTNF1	Homo sapiens	Q9BXJ1	Y2H Array	25416956
Intra	SGTA	O43765	C1QTNF1	Homo sapiens	Q9BXJ1	Y2H Pooling	16189514
Intra	SGTA	O43765	SPPL2A	Homo sapiens	Q8TCT8	Validated Y2H	32296183
Intra	SGTA	O43765	SPPL2A	Homo sapiens	Q8TCT8	Y2H Array	25416956
Intra	SGTA	O43765	SPPL2A	Homo sapiens	Q8TCT8	Y2H Pooling	16189514
Intra	SGTA	O43765	SPPL2A	Homo sapiens	Q8TCT8	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	HSPA13	Homo sapiens	P48723	Validated Y2H	32296183
Intra	SGTA	O43765	HSPA13	Homo sapiens	P48723	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	SYT4	Homo sapiens	Q9H2B2	Validated Y2H	25416956
Intra	SGTA	O43765	SYT4	Homo sapiens	Q9H2B2	Y2H Pooling	16189514
Intra	SGTA	O43765	SYT4	Homo sapiens	Q9H2B2	Validated Y2H	32296183
Intra	SGTA	O43765	SYT4	Homo sapiens	Q9H2B2	Y2H Array	25416956
Intra	SGTA	O43765	SYT11	Homo sapiens	Q9BT88	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	SYT11	Homo sapiens	Q9BT88	Validated Y2H	32296183
Intra	SGTA	O43765	TMPRSS11D	Homo sapiens	O60235	Validated Y2H	32296183
Intra	SGTA	O43765	DMKN	Homo sapiens	Q6E0U4	Validated Y2H	32296183
Intra	SGTA	O43765	DMKN	Homo sapiens	Q6E0U4	Y2H Array	32296183
Intra	SGTA	O43765	DMKN	Homo sapiens	Q6E0U4	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	KCNA1	Homo sapiens	Q09470	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	KCNA1	Homo sapiens	Q09470	Y2H Array	32296183
Intra	SGTA	O43765	KCNA1	Homo sapiens	Q09470	Validated Y2H	32296183
Intra	SGTA	O43765	CREB3L3	Homo sapiens	Q68CJ9	Y2H Array	32296183
Intra	SGTA	O43765	CREB3L3	Homo sapiens	Q68CJ9	Validated Y2H	32296183
Intra	SGTA	O43765	CREB3L3	Homo sapiens	Q68CJ9	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	GIP	Homo sapiens	P09681	Validated Y2H	25416956
Intra	SGTA	O43765	GIP	Homo sapiens	P09681	Validated Y2H	32296183
Intra	SGTA	O43765	GIP	Homo sapiens	P09681	Y2H Array	25416956
Intra	SGTA	O43765	NAXD	Homo sapiens	Q8IW45	Validated Y2H	32296183
Intra	SGTA	O43765	NAXD	Homo sapiens	Q8IW45	Y2H Array	25416956
Intra	SGTA	O43765	NAXD	Homo sapiens	Q8IW45	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	NAXD	Homo sapiens	Q8IW45	Y2H	21516116
Intra	SGTA	O43765	ERP29	Homo sapiens	P30040	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	ERP29	Homo sapiens	P30040	Y2H Array	32296183
Intra	SGTA	O43765	ERP29	Homo sapiens	P30040	Validated Y2H	32296183
Intra	SGTA	O43765	IGFBP6	Homo sapiens	P24592	Validated Y2H	32296183
Intra	SGTA	O43765	UBQLN2	Homo sapiens	Q9UHD9	Validated Y2H	32296183
Intra	SGTA	O43765	UBQLN2	Homo sapiens	Q9UHD9	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	UBQLN2	Homo sapiens	Q9UHD9	Y2H Array	32296183
Intra	SGTA	O43765	RCN1	Homo sapiens	Q15293	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	RCN1	Homo sapiens	Q15293	Y2H Array	32296183
Intra	SGTA	O43765	RCN1	Homo sapiens	Q15293	Validated Y2H	32296183
Intra	SGTA	O43765	MRAP2	Homo sapiens	Q96G30	Validated Y2H	32296183
Intra	SGTA	O43765	MRAP2	Homo sapiens	Q96G30	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	MRAP2	Homo sapiens	Q96G30	Y2H Array	32296183
Intra	SGTA	O43765	ERP27	Homo sapiens	Q96DN0	Y2H Array	31515488
Intra	SGTA	O43765	ERP27	Homo sapiens	Q96DN0	Validated Y2H	25416956
Intra	SGTA	O43765	ERP27	Homo sapiens	Q96DN0	Validated Y2H	32296183
Intra	SGTA	O43765	ERP27	Homo sapiens	Q96DN0	Y2H Array	25416956
Intra	SGTA	O43765	ITPRIPL1	Homo sapiens	Q6GPH6	Validated Y2H	25416956
Intra	SGTA	O43765	ITPRIPL1	Homo sapiens	Q6GPH6	Y2H Array	25416956
Intra	SGTA	O43765	ZG16B	Homo sapiens	Q96DA0	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	ZG16B	Homo sapiens	Q96DA0	Validated Y2H	32296183
Intra	SGTA	O43765	ZG16B	Homo sapiens	Q96DA0	Y2H Array	25416956
Intra	SGTA	O43765	CYB5R1	Homo sapiens	Q9UHQ9	Validated Y2H	32296183
Intra	SGTA	O43765	PPIC	Homo sapiens	P45877	Y2H Prey Pooling	25416956
Intra	SGTA	O43765	PPIC	Homo sapiens	P45877	Validated Y2H	32296183
Intra	SGTA	O43765	SERPINE1	Homo sapiens	P05121	Validated Y2H	25416956
Intra	SGTA	O43765	SERPINE1	Homo sapiens	P05121	Validated Y2H	32296183
Intra	SGTA	O43765	DKK3	Homo sapiens	Q9UBP4	Y2H Array	32296183
Intra	SGTA	O43765	DKK3	Homo sapiens	Q9UBP4	Y2H Prey Pooling	32296183
Intra	SGTA	O43765	DKK3	Homo sapiens	Q9UBP4	Validated Y2H	32296183
Intra	SGTA	O43765	COL1A2	Homo sapiens	P08123	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant SGTA Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71033	SGTA Protein, Human (His)	O43765 (M1-E313)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-124824	Methyl gerfelin	Inhibitor	/	Unkown
HY-RS12816	SGTA Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SGTA	MGD	MGI:1098703
Rattus norvegicus	SGTA	RGD	RGD:620815
Felis catus	SGTA	VGNC	VGNC:65086
Macaca mulatta	SGTA	VGNC	VGNC:77197
Bos taurus	SGTA	VGNC	VGNC:34553
Canis familiaris	SGTA	VGNC	VGNC:46107
Others	SGTA	NCBI

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