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Results for "

NHS Group

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Cytotoxin (2) ADC Linker (78) Biochemical Assay Reagents (59) DNA Stain (1) Drug Derivative (1) Drug Intermediate (2) Drug-Linker Conjugates for ADC (3) E3 Ligase Ligand-Linker Conjugates (1) Fluorescent Dye (62) Ligands for E3 Ligase (1) Liposome (2) Microtubule/Tubulin (2) PROTAC Linkers (78) Radionuclide-Drug Conjugates (RDCs) (1) Reactive Oxygen Species (1)
By Research Areas:	Cancer (143) Inflammation/Immunology (1) Metabolic Disease (1)
Click Chemistry:	ADC Synthesis (51) TCO (14) Labeling and Fluorescence Imaging (1) DBCO (27) PROTAC Synthesis (65) BCN (10) Azide (40) Tetrazine (15) Alkynes (17)
Oligonucleotides:	Phospholipids (1)

280

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

MCE Kits

123

Click Chemistry

Oligonucleotides

Targets Recommended: HMG Family

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-160773A

DBCO-C3-amide-PEG6-NHS ester	Biochemical Assay Reagents	Others
DBCO-C3-amide-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-C3-amide-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-145090

DBCO-N-bis(PEG4-NHS ester)	PROTAC Linkers ADC Linker	Others
DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling. DBCO-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-160773

DBCO-PEG6-NHS ester	Biochemical Assay Reagents	Others
DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-W800684

Benzyloxy carbonyl-PEG4-NHS ester	Biochemical Assay Reagents	Others
Benzyloxy carbonyl-PEG4-NHS ester is a reagent with a benzyl protecting group and an NHS ester. The NHS ester reacts with primary amines (-NH2). The benzyl protecting group can be removed by hydrogenolysis.

HY-W615173

NHS ester-C2-NHCO-C2-NHS	Biochemical Assay Reagents	Others
NHS ester-C2-NHCO-C2-NHS is a heterobifunctional PEG linker, featuring a terminal NHS ester that can be used to label amine compounds and maleimide group for reactions with thiol groups.

HY-D2801

FITC-PEG-NHS (MW 400)	Fluorescent Dye	Others
FITC-PEG-NHS (MW 400) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG-NHS (MW 400) can be used for fluorescent labeling and imaging .

HY-D2801A

FITC-PEG-NHS (MW 1000)	Fluorescent Dye	Others
FITC-PEG-NHS (MW 1000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG-NHS (MW 1000) can be used for fluorescent labeling and imaging .

HY-D2801B

FITC-PEG-NHS (MW 3400)	Fluorescent Dye	Others
FITC-PEG-NHS (MW 3400) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG-NHS (MW 3400) can be used for fluorescent labeling and imaging .

HY-D2801C

FITC-PEG-NHS (MW 5000)	Fluorescent Dye	Others
FITC-PEG-NHS (MW 5000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG-NHS (MW 5000) can be used for fluorescent labeling and imaging .

HY-D2477

Sulfo-QSY21-NHS	Fluorescent Dye	Others
Sulfo-QSY21-NHS is a fluorescent dye, which contains a NHS group that can react with amine groups (-NH2) in proteins or other molecules to form stable amide bonds. Sulfo-QSY21-NHS can be used in the synthesis of activity-based probes (ABPs) .

HY-141121

T-Butoxycarbonyl-PEG1-NHS ester	Drug Intermediate	Others
T-Butoxycarbonyl-PEG1-NHS ester contains a t-boc protecting group and an NHS ester moiety. T-Butoxycarbonyl-PEG1-NHS ester can be used for the modification and labeling of biomolecules.

HY-130085

Mal-PEG6-NHS ester	ADC Linker	Cancer
Mal-PEG6-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester.

HY-126504

Mal-PEG2-NHS ester	ADC Linker	Cancer
Mal-PEG2-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and an NHS ester.

HY-126511

Propargyl-C1-NHS ester 1 Publications Verification	ADC Linker	Cancer
Propargyl-C1-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-126512

Propargyl-C2-NHS ester	ADC Linker	Cancer
Propargyl-C2-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-129526

Mal-PEG3-NHS ester	ADC Linker	Cancer
Mal-PEG3-NHS ester is a noncleavable ADC linker containing a Maleimide group. Mal-PEG3-NHS ester is used for making antibody-drug conjugate .

HY-D2105

TAMRA-PEG3-NHS	Fluorescent Dye	Others
TAMRA-PEG3-NHS is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-D2106

TAMRA-PEG4-NHS	Fluorescent Dye	Others
TAMRA-PEG4-NHS is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-D2107

TAMRA-PEG8-NHS	Fluorescent Dye	Others
TAMRA-PEG8-NHS is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-141167B

(S)-TCO-PEG4-NHS ester	ADC Linker	Cancer
(S)-TCO-PEG4-NHS ester is an ADC linker containing 4 PEG units. (S)-TCO-PEG4-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

HY-141169B

(R,E)-TCO-PEG8-NHS ester	ADC Linker	Cancer
(R)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (R)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

HY-141169A

(S,E)-TCO2-PEG8-NHS ester	ADC Linker	Cancer
(S)-TCO-PEG8-NHS ester is an ADC linker containing 8 PEG units. (S)-TCO-PEG8-NHS ester can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.

HY-140025

Propargyl-PEG4-CH2CO2-NHS	ADC Linker	Cancer
Propargyl-PEG4-CH2CO2-NHS (compound P-7) is a PEG derivative containing a propargyl group and an NHS group. Propargyl-PEG4-CH2CO2-NHS is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG4-CH2CO2-NHS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-156491

Me-Tet-PEG9-NHS	ADC Linker	Cancer
Me-Tet-PEG9-NHS is an ADC Linker containing 9 PEG units. Me-Tet-PEG9-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

HY-156476

Me-Tet-PEG2-NHS	ADC Linker	Cancer
Me-Tet-PEG2-NHS is an ADC Linker containing 2 PEG units. Me-Tet-PEG2-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

HY-156313

Me-Tet-PEG4-NHS	ADC Linker	Cancer
Me-Tet-PEG4-NHS is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

HY-156490

Me-Tet-PEG5-NHS	ADC Linker	Cancer
Me-Tet-PEG5-NHS is an ADC Linker containing 5 PEG units. Me-Tet-PEG5-NHS can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups.

HY-164165

Paclitaxel-2′-succinate NHS ester	Microtubule/Tubulin Drug Derivative	Cancer
Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy .

HY-140272

DBCO-PEG4-NHS ester 1 Publications Verification	PROTAC Linkers	Cancer
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140273

DBCO-PEG8-NHS ester	PROTAC Linkers	Cancer
DBCO-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG8-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-138744

DBCO-PEG13-NHS ester	PROTAC Linkers	Cancer
DBCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG13-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-133439

BCN-PEG4-NHS ester	PROTAC Linkers ADC Linker	Cancer
BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140274

DBCO-PEG12-NHS ester	PROTAC Linkers	Cancer
DBCO-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG12-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140271

DBCO-PEG1-NHS ester	PROTAC Linkers	Cancer
DBCO-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG1-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-138734

Propargyl-PEG2-NHS ester	PROTAC Linkers	Cancer
Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG2-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151758

Methyltetrazine-PEG12-NHS ester	ADC Linker	Others
Methyltetrazine-PEG12-NHS ester is a click chemistry reagent containing an azide group. Methyltetrazine-PEG12-NHS ester reacts with compounds containing TCO to form stable covalent bonds .

HY-138756

PC DBCO-PEG4-NHS ester	PROTAC Linkers	Cancer
PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . PC DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-141171

TCO-PEG24-NHS ester	PROTAC Linkers	Cancer
TCO-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG24-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-140070

endo-BCN-PEG8-NHS ester	PROTAC Linkers	Cancer
endo-BCN-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG8-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-141167A

TCO-PEG4-NHS ester	PROTAC Linkers	Cancer
TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-140276

DBCO-NHCO-PEG13-NHS ester	PROTAC Linkers	Cancer
DBCO-NHCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG13-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140069

endo-BCN-PEG4-NHS ester	PROTAC Linkers	Cancer
endo-BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-126513

Propargyl-PEG1-NHS ester	ADC Linker	Cancer
Propargyl-PEG1-NHS ester is a nonclaevable 1-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140275

DBCO-NHCO-PEG5-NHS ester	PROTAC Linkers	Cancer
DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-126516

Propargyl-PEG4-NHS ester	ADC Linker	Cancer
Propargyl-PEG4-NHS ester is a nonclaevable 4-unit PEG linker for antibody-agent-conjugation (ADC). Propargyl-PEG4-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-140068

endo-BCN-PEG3-NHS ester	PROTAC Linkers	Cancer
endo-BCN-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . endo-BCN-PEG3-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-141166A

(S,E)-TCO2-PEG3-NHS ester	Biochemical Assay Reagents	Cancer
(S,E)-TCO2-PEG3-NHS ester is NH₂ reactive, and can be used in chemical synthesis. (S,E)-TCO2-PEG3-NHS ester contains TCO groups, which can undergo specific "click" reactions with tetrazine groups .

HY-133375

DBCO-NHCO-PEG2-NHS ester	PROTAC Linkers	Cancer
DBCO-NHCO-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG2-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-126974

Propargyl-PEG3-NHS ester	ADC Linker PROTAC Linkers	Cancer
Propargyl-PEG3-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG3-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG3-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-126885

DBCO-PEG5-NHS ester	ADC Linker PROTAC Linkers	Cancer
DBCO-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG5-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Cat. No.	Product Name	Type

HY-D2801

FITC-PEG-NHS (MW 400)	Fluorescent Dyes/Probes
FITC-PEG-NHS (MW 400) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG-NHS (MW 400) can be used for fluorescent labeling and imaging .

HY-D2801A

FITC-PEG-NHS (MW 1000)	Fluorescent Dyes/Probes
FITC-PEG-NHS (MW 1000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG-NHS (MW 1000) can be used for fluorescent labeling and imaging .

HY-D2801B

FITC-PEG-NHS (MW 3400)	Fluorescent Dyes/Probes
FITC-PEG-NHS (MW 3400) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG-NHS (MW 3400) can be used for fluorescent labeling and imaging .

HY-D2801C

FITC-PEG-NHS (MW 5000)	Fluorescent Dyes/Probes
FITC-PEG-NHS (MW 5000) is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and a hydroxysuccinimide (NHS) group. The NHS group can react with amine-containing groups. FITC-PEG-NHS (MW 5000) can be used for fluorescent labeling and imaging .

HY-D2477

Sulfo-QSY21-NHS	Fluorescent Dyes/Probes
Sulfo-QSY21-NHS is a fluorescent dye, which contains a NHS group that can react with amine groups (-NH2) in proteins or other molecules to form stable amide bonds. Sulfo-QSY21-NHS can be used in the synthesis of activity-based probes (ABPs) .

HY-D2105

TAMRA-PEG3-NHS	Fluorescent Dyes/Probes
TAMRA-PEG3-NHS is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-D2106

TAMRA-PEG4-NHS	Fluorescent Dyes/Probes
TAMRA-PEG4-NHS is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-D2107

TAMRA-PEG8-NHS	Fluorescent Dyes/Probes
TAMRA-PEG8-NHS is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-D1309

Sulfo-cyanine3 NHS ester sodium	Fluorescent Dyes/Probes
Sulfo-cyanine3 NHS ester sodium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.

HY-D1310

Sulfo-cyanine3.5 NHS ester tripotassium	Fluorescent Dyes/Probes
Sulfo-cyanine3.5 NHS ester tripotassium is a water-soluble cyanine dye that contains NHS ester groups and is amino-reactive.

HY-D1848

Sulfo-Cy3-NHS disodium	Fluorescent Dyes/Probes
Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.

HY-D2746

Cy5.5 bis-NHS ester	Fluorescent Dyes/Probes
Cy5.5 bis-NHS ester is a reactive cyanine dye containing NHS ester which can be used to label amine groups in peptides, proteins, and oligonucleotides.

HY-D2741

MB 488 NHS ester	Fluorescent Dyes/Probes
MB 488 NHS ester is a fluroescent agent with a terminal NHS ester group. MB 488 NHS ester is a green fluorescent, very hydrophilic dye molecule that has a maximal absorption of 501 nm and emission at 524 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

HY-123687

DBCO-Sulfo-NHS ester sodium	Dyes
DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-D2166

AF 594 NHS ester	Fluorescent Dyes/Probes
AF 594 NHS ester is a derivative of the red fluorescent dye AF 594 with high fluorescence quantum yield and high photostability (Ex=594 nm, Em=615 nm). AF 594 NHS ester can form an ester bond by reacting the NHS group with ammonia, with maximum excitation wavelength of 594 nm .

HY-D1568

Sulfo-Cy7.5 NHS ester	Dyes
Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .

HY-D1568A

Sulfo-Cy7.5 NHS ester tripotassium

Dyes

Sulfo-Cy7.5 NHS ester tripotassium is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester tripotassium contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester tripotassium can be used for the research of NIR imaging applications .

HY-135414A

Cyanine5 NHS ester bromide	Fluorescent Dyes/Probes
Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues .

HY-135414

Cyanine5 NHS ester chloride	Fluorescent Dyes/Probes
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-D1653

BDP 581/591 NHS ester

Fluorescent Dyes/Probes

BDP 581/591 NHS ester is a a borondipyrromethene dye (Ex=585 nm, Em=594 nm) that has relatively long fluorescence lifetime and two photon excitation cross section. BDP 581/591 NHS ester can be used for fluorescence polarization analysis and also reacts with reactive oxygen species (ROS) and alter fluorescence. BDP 581/591 NHS ester is also an NHS ester derivative that can be used to bind primary and secondary amine groups of proteins, peptides and other molecules.

HY-133535

PA Janelia Fluor® 646, SE

PA-JF646-NHS

Dyes

PA Janelia Fluor® 646, SE (PA-JF646-NHS), a photoactivatable fluorescent dye, is an NHS ester for coupling to primary amine groups. PA-JF646-NHS is non-fluorescent until activated at 365 nm. NHS ester can be converted to relevant substrate for use in self-labeling tag systems, e.g.HaloTag ^® and SNAP-tag ^®. PA-JF646-NHS is used for single molecule tracking and super resolution microscopy in live cells, specifically live cell sptPALM and fixed cell PALM. (λ_{Excitation/emission}~650/664 nm). Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.

HY-135414B

Cyanine5 NHS ester iodide 1 Publications Verification	Fluorescent Dyes/Probes
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-132270

FAM amine, 5-isomer	Fluorescent Dyes/Probes
FAM amine, 5-isomer is a fluorescein linker that undergoes enzymatic transamination. The addition of the amine group makes the compound more reactive with carboxylic acids, activated NHS ester and other carbonyl groups.

HY-D1849

Cy3B NHS ester	Fluorescent Dyes/Probes
Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.

HY-149117

AF430 NHS ester	Fluorescent Dyes/Probes
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .

HY-D1658

BDP 581/591 amine hydrochloride	Fluorescent Dyes/Probes
BDP 581/591 amine hydrochloride is a BODIPY dye linker. BDP 581/591 is a universal, photostable fluorophore. The addition of the amine group allows for the compound to react with carboxylic acids, activated NHS esters and other carbonyl groups .

HY-D2328

Alexa Fluor 680 NHS ester Alexa Fluor 680 succinimidyl ester	Dyes
Alexa Fluor 680 NHS ester is a near-infrared (NIR) fluorescent dye. The Alexa Fluor 680 group has an absorption maximum at 679 nm and an emission maximum at 720 nm .

HY-D1730A

AF488 NHS ester TEA 1 Publications Verification	Fluorescent Dyes/Probes
AF488 NHS ester TEA is an amine specific fluorescence probe (λ_em=525 nm=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization. AF488 exhibits the λ_em and λ_ex wavelength of 520 nm and 470 nm, respectively .

HY-D1372

Cyanine3 amine hydrochloride	Fluorescent Dyes/Probes
Cyanine3 amine hydrochloride, an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine hydrochloride has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λ_ex=555 nm, λ_em=570 nm) .

HY-W998707

TAMRA amine, 5-isomer hydrochloride	Fluorescent Dyes/Probes
TAMRA amine, 5-isomer hydrochloride is a rhodamine dye with excitation/emission maximum 553/575 nm. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

HY-D1372A

Cyanine3 amine TFA	Fluorescent Dyes/Probes
Cyanine3 amine (TFA), an analog of Cyanine3 amine, is a potent green fluorescent dye. Cyanine3 amine (TFA) has the primary amine group and is covalently coupled with reactive groups such as NHS esters, carboxy groups (after carbodiimide activation), and epoxides. (λ_ex=555 nm, λ_em=570 nm) .

HY-D1085

AMCA-X SE	Fluorescent Dyes/Probes
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .

HY-137023

Sulfo-Cy7 amine	Fluorescent Dyes/Probes
Sulfo-Cy7 amine is a cyanine containing a free amine group, which can be conjugated with a variety of functionalities, including NHS esters, and epoxides. This NIR dye amine can be used to derivate various targets by the reaction with electrophilic groups, and also by enzymatical reactions involving transamination.

HY-D0049

6-TAMRA-SE 1 Publications Verification 6-TAMRA-NHS ester; 6-Carboxytetramethylrhodamine N-succinimidyl ester	Oligonucleotide Labeling
6-TAMRA-SE (6-TAMRA-NHS ester) is a fluorescent dye carrying the amine reactive group. 6-TAMRA-SE is one of the traditional fluorophores used for automated DNA sequencing .

HY-172284

6-TAMRA cadaverine	Fluorescent Dyes/Probes
6-TAMRA cadaverine has achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.

HY-D2735

QSY-9-succinimidyl ester

Dyes

QSY-9-succinimidyl ester is a nonfluorescent acceptor molecule with a terminal NHS ester group. QSY-9-succinimidyl ester has a wide and intense quenching range from 500-600 nm that makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with fluorescent dyes at 500 nm to 600 nm. The NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

HY-D2764

Difluorocarboxyfluorescein cadaverine, 5-isomer	Fluorescent Dyes/Probes
Difluorocarboxyfluorescein cadaverine, 5-isomer is a carbonyl reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond.

HY-D2768

BP Fluor 430 NHS ester

Fluorescent Dyes/Probes

BP Fluor 430 NHS Ester is a water-soluble, green-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10. The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 430 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection.

HY-D2771

BP Fluor 405 NHS ester

Fluorescent Dyes/Probes

BP Fluor 405 NHS Ester is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10. The NHS ester (or succinimidyl ester) is the most popular amine reactive group for labeling with the primary amines of proteins (Lys), amine-modified oligonucleotides, and other amine-containing molecules. Proteins can be labeled with BP Fluor 405 NHS Ester at high molar ratios without significant self-quenching, leading to brighter conjugates and more sensitive detection. BP Fluor 405 conjugates can also be used for the detection of abundance targets.

HY-D1756

ROX NHS ester, 6-isomer	Fluorescent Dyes/Probes
ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer.

HY-D1363

BDP R6G maleimide

Fluorescent Dyes/Probes

BDP R6G maleimide is a borodipyrromethane fluorophore with absorption and emission wavelengths similar to those of R6G rhodamine. Sulfhydryl labelling is a common protein modification where the cysteine residues in the protein allow more site-specific labelling than the NHS ester of the amine group. BDP R6G maleimide is a thiol reactive dye that reacts with thiol groups to form thioester bonds .

HY-D1596

Cyanine 3.5 chloride Cy3.5 NHS ester chloride; Cy 3.5 chloride	Fluorescent Dyes/Probes
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λ_ex=591 nm, λ_em=604 nm) .

HY-D0819A

CY5-SE triethylamine salt Maximum Cited Publications 16 Publications Verification Cy5 NHS Ester triethylamine salt; Sulfo-Cyanine5 Succinimidyl Ester triethylamine salt	Fluorescent Dyes/Probes
Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm) .

HY-D1596A

Cyanine 3.5 bromide Cy3.5 NHS ester bromide; Cy 3.5 bromide	Fluorescent Dyes/Probes
Cyanine 3.5 bromide (Cy3.5 NHS ester bromide) is an analog of the Cy3.5 fluorophore. Cyanine 3.5 bromide is a red reactive fluorescent dye. Cyanine 3.5 bromide is used to label amino groups in peptides, proteins, and oligonucleotides. (λ_ex=591 nm, λ_em=604 nm) .

HY-42972G

DBCO-acid (GMP)

Fluorescent Dye

DBCO-acid GMP is a GMP grade DBCO-acid (HY-42972). DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and agent-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690) . DBCO-acid is a click chemistry reagent, itcontains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-D1794

Vari Fluor 405 SE VF 405 SE	Dyes
Vari Fluor 405 SE (VF 405 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=399 nm/421 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1791

Vari Fluor 750 SE VF 750 SE	Dyes
Vari Fluor 750 SE (VF 750 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=747 nm/770 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1797

Vari Fluor 660 SE VF 660 SE	Dyes
Vari Fluor 660 SE (VF 660 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=660 nm/679 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1802

Vari Fluor 425 SE VF 425 SE	Dyes
Vari Fluor 425 SE (VF 425 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=430 nm/475 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1800

Vari Fluor 680 SE VF 680 SE	Fluorescent Dyes/Probes
Vari Fluor 680 SE (VF 680 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=680 nm/700 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

Cat. No.	Product Name	Type

HY-D0975

Sulfo-SMCC sodium 4 Publications Verification	Biochemical Assay Reagents
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.

HY-140677

mPEG-amine (MW 5000)

mPEG-NH2 (MW 5000)

Drug Delivery

mPEG-amine (mPEG-NH2) (MW 5000) is a modifier that can replace the sulfonic acid portion of the dye molecule to increase the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes. mPEG-amine can also form amide bonds with carboxyl groups on the surface of microspheres under the mediation of EDC and Sulfo-NHS to form a PEG coating on the surface of fluorescent microspheres for large-scale rotational cytoplasmic flow studies .

HY-W437745

Desthiobiotin-NHS ester	Biochemical Assay Reagents
Desthiobiotin-NHS ester is a biotinylated biochemical assay reagent that reacts with amine groups (such as lysine residues) of proteins or other biomolecules to form stable amide bonds. Desthiobiotin-NHS ester can be used as probes for metalloproteins .

HY-42972G

DBCO-acid (GMP)

Biochemical Assay Reagents

Cat. No.	Product Name		Classification

HY-145547

1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine 14:0 Lyso PE; 1-Myristoyl-2-hydroxy-sn-glycero-3-PE; 1-Tetradecanoyl-sn-glycero-3-phosphoethanolamine		Phospholipids
1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells . Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls .

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