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albicans

" in MedChemExpress (MCE) Product Catalog:

205

Inhibitors & Agonists

1

Fluorescent Dye

1

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36

Peptides

47

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7

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0101
    Fluconazole
    Maximum Cited Publications
    12 Publications Verification

    UK-49858

    Fungal Antibiotic Bacterial Infection Cancer
    Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
    Fluconazole
  • HY-N11772

    Fungal Infection
    Mutanocyclin is a potent antifungal agent. Mutanocyclin inhibits Candida albicans (C. albicans) filamentation. Mutanocyclin decreases the mRNA expression of HWP1, ECE1, FLO8, TEC1. Mutanocyclin inhibits yeast-form in ex vivo mouse .
    Mutanocyclin
  • HY-W142410

    Fungal Others
    2-Dodecanol inhibits hyphal formation and SIR2 expression in C. albicans .
    2-Dodecanol
  • HY-B0101R

    Fungal Antibiotic Bacterial Infection Cancer
    Fluconazole (Standard) is the analytical standard of Fluconazole. This product is intended for research and analytical applications. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
    Fluconazole (Standard)
  • HY-143405

    Fungal Infection
    Antifungal agent 24 (Compound 6) is an antifungal agent against Candida albicans with a MIC value of 0.03 μg/mL .
    Antifungal agent 24
  • HY-N7784

    Antibiotic Bacterial Infection
    Liriodenine methiodide is an antibiotic that is active against C. albicans and S. cereuisiae with antimicrobial activities .
    Liriodenine methiodide
  • HY-146116

    Fungal Infection
    Antifungal agent 32 (compound 1a) is a potent antifungal agent. Antifungal agent 32 inhibits Candida albicans filamentation and biofilm formation. Antifungal agent 32 inhibits the morphological switching of Candida albicans and its adherence to epithelial cells. Antifungal agent 32 can be used for Candida albicans infections research .
    Antifungal agent 32
  • HY-147238

    Fungal Infection
    Antifungal agent 35 (compound 24) is a potent antifungal agent. Antifungal agent 35 is a potent enhancer of antifungal activity of Fluconazole against C. albicans .
    Antifungal agent 35
  • HY-121169

    Ro 14-4767; Ro 14-4767/000

    Fungal Infection
    Amorolfine (Ro 14-4767) is an antifungal agent. Amorolfine ameliorates the onychomycosis through inhibition of ergosterol biosynthesis. Amorolfine inhibits Candida albicans with a MIC of 0.404 µg/mL .
    Amorolfine
  • HY-150584

    Fungal Infection
    Chitin synthase inhibitor 3 (compound 2d) is a potent chitin synthase inhibitor with an IC50 value of 0.16 mM, and MIC of 1 µg/mL against candida albicans. Antifungal activity .
    Chitin synthase inhibitor 3
  • HY-P10304A

    Cyclo(Pro-Arg) TFA

    Parasite Infection
    Cyclo(Arg-Pro) (Cyclo(Pro-Arg)) TFA is a chitinase inhibitor. Cyclo(Arg-Pro) TFA inhibits cell separation of Saccharomyces cerevisiae, without affecting its growth. Cyclo(Arg-Pro) TFA inhibits the morphological change of Candida albicans from yeast form to filamentous form .
    Cyclo(Arg-Pro) TFA
  • HY-143334

    Fungal Infection
    Antibacterial agent 84 is an antifungal compound. Antibacterial agent 84 inhibits candidiasis in a CNB1-dependent way. Antibacterial agent 84 inhibits the C. albicans biofilm's viability .
    Antifungal agent 84
  • HY-163540

    Aminoacyl-tRNA Synthetase Fungal Infection
    NP-BTA is an allosteric inhibitor for glutaminyl-tRNA synthetase (GlnRS). NP-BTA exhibits antifungal efficacy against Candida albicans, with MIC50 of 6.25 μM .
    NP-BTA
  • HY-122134

    Fungal Infection
    SC-58272 is a potent and selective dipeptide N-myristoyltransferase (Nmt) inhibitor with an IC50 of 56 nM for C. albicans (strain B311) Nmt. SC-58272 shows 250-fold selective for the fungal enzyme compared to human enzyme .
    SC-58272
  • HY-125152

    CndD

    Antibiotic Fungal Infection
    Candicidin D (CndD) is an antibiotic, which exhibits antifungal activity through interaction with steroids in cell membranes. Candicidin D inhibits S. cerevisiae, Candida albicans and other Candida spp. with MIC of 0.25-1 μg/mL in RPMI-1640 medium.
    Candicidin D
  • HY-129260

    3-Amino-3-deoxyglucose

    Fungal Infection
    Kanosamine (3-Amino-3-deoxyglucose) is an antibiotic against Saccharomyces cerevisiae and human pathogenic fungi Candida albicans. Kanosamine exhibits antifungal activity through inhibition of cell wall synthesis and inhibition of GlcN-6-P synthase with phosphorylated kanosamine-6-phosphate in cytoplasma .
    Kanosamine
  • HY-135445

    21-Norrapamycin

    Fungal Infection
    Prolylrapamycin (21-Norrapamycin) is the derivative of Rapamycin (HY-10219). Prolylrapamycin exhibits antifungal activity, that inhibits Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum with MIC of 0.125-2 μg/mL .
    Prolylrapamycin
  • HY-164620

    Fungal Infection
    Antifungal agent 112 (Compound 1e) exhibits antifungal activity against Candida albicans, Aspergillus niger and Aspergillus fumigatus with MIC of 0.0024, 0.0022 and 0.0028 M, respectively .
    Antifungal agent 112
  • HY-146190

    Bacterial Antibiotic Infection Inflammation/Immunology
    Callophycin A, a red seaweed derived metabolite, possessing potent activity against Candida albicans with MIC of 62.5~250 mg/L. Callophycin A significantly reduces fungal burden of vaginal candidiasis induced mice, also decreases inflammatory response and immune molecules .
    Callophycin A
  • HY-136759

    Fungal Infection
    CYP51-IN-2 (compound 1i), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC80 of 62.5 for Microsporum gypseum and Candida albicans .
    CYP51-IN-9
  • HY-136762

    Fungal Infection
    CYP51-IN-2 (compound 1l), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC80 of 15.6 ng/mL for Microsporum gypseum and Candida albicans .
    CYP51-IN-12
  • HY-136764

    Fungal Infection
    CYP51-IN-2 (compound 1n), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC80 of 1 μg/mL for Microsporum gypseum and Candida albicans .
    CYP51-IN-14
  • HY-W016288

    2,3-Naphthalenedicarboxaldehyde; Naphthalene-2,3-dialdehyde

    Fungal Infection
    Naphthalene-2,3-Dicarboxaldehyde (2,3-Naphthalenedicarboxaldehyde), a phthaldehyde derivative, is a fungal ASADH inhibitor (Ki: 45 渭M). Naphthalene-2,3-Dicarboxaldehyde inhibits the growth of C. albicans CAF2-1 with IC50 of 58.2 渭M and MIC of 12 渭g/mL .
    Naphthalene-2,3-Dicarboxaldehyde
  • HY-136754

    Fungal Infection
    CYP51-IN-2 (compound 1d), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC80 of 15.6 ng/mL for Microsporum gypseum and Candida albicans .
    CYP51-IN-4
  • HY-P5625

    Bacterial Infection
    ROAD-1 is an oral mucosal α-defensin of Rhesus Macaque. ROAD-1 is active against S. aureus, E. coli, and C. albicans .
    ROAD-1
  • HY-120432

    Others Infection
    CaMdr1p-IN-1 (Compound A) is an inhibitor for the major facilitator superfamily transporter CaMdr1p. CaMdr1p-IN-1 exhibits chemosensitizing efficacy. CaMdr1p-IN-1 synergizes with Fluconazole (HY-B0101), that inhibits CaMdr1p overexpressing Candida albicans with MIC of 10 μM .
    CaMdr1p-IN-1
  • HY-W012126

    2,6-Dichloro-N-phenylaniline

    Bacterial Infection Cancer
    2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium (HY-15037) and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells.
    2,6-Dichlorodiphenylamine
  • HY-136757

    Fungal Infection
    CYP51-IN-2 (compound 1g), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC80s of 62.5 and 250 ng/mL for Microsporum gypseum and Candida albicans, respectively .
    CYP51-IN-7
  • HY-136763

    Fungal Infection
    CYP51-IN-2 (compound 1m), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC80s of 62.5 and 250 ng/mL for Microsporum gypseum and Candida albicans, respectively .
    CYP51-IN-13
  • HY-N2105

    L-Dicentrine

    Fungal Bacterial Infection
    (-)-Dicentrine is an aporphine alkaloid that can be isolated from the stem bark of Talauma arcabucoana. (-)-Dicentrine shows moderate growth inhibition against Staphylococcus aureus and Candida albicans .
    (-)-Dicentrine
  • HY-136752

    Fungal Infection
    CYP51-IN-2 (compound 1b), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows 64 and 128 times higher activity than that of Fluconazole against Microsporum gypseum and Candida albicans, respectively .
    CYP51-IN-2
  • HY-136756

    Fungal Infection
    CYP51-IN-2 (compound 1f), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC80s of 62.5 and 15.6 ng/mL for Microsporum gypseum and Candida albicans, respectively .
    CYP51-IN-6
  • HY-136758

    Fungal Infection
    CYP51-IN-2 (compound 1h), a Fluconazole (HY-B0101) analog, is a potent antifungal agent. CYP51-IN-2 shows MIC80s of 15.6 and 62.5 ng/mL for Microsporum gypseum and Candida albicans, respectively .
    CYP51-IN-8
  • HY-P10408

    EGFR MMP Calcium Channel Infection Inflammation/Immunology
    Candidalysin is a cytolytic peptide toxin, which is initially isolated from Candida albicans and exhibits virulent and avirulent characters. Candidalysin activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) of host cells, activates matrix metalloproteinase (MMP) and calcium flux, resulting in inflammatory responses and recruitment of immune cells. Candidalysin exhibits cytotoxicity by dealing membran damage to host cells .
    Candidalysin
  • HY-N3837

    Isotaraxerol; 3α-Taraxerol

    Bacterial Infection
    Epitaraxerol (compound 6) is a natural product isolated from the leaves of E. neriifolia. Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes, A. niger, S. aureus, E. coli, P. aeruginosa, and B. subtilis .
    Epitaraxerol
  • HY-N12606

    Fungal Infection
    Neodidymelliosides A (compound 1)It is a secondary metabolite of fungi and has a significant inhibitory effect on Staphylococcus aureus and Candida albicans biofilms. Neodidymelliosides AIt also has anti-cancer activity and can inhibit KB3.1 (cervix),PC-3 (prostate),MCF-7(breast),SKOV-3 (ovary),A431 (skin )and A549 (lung )Cell viability of cell lines .
    Neodidymelliosides A
  • HY-146060

    Bacterial Fungal Infection
    Antibacterial agent 100 (Compound 7c) is an antibacterial and antifungal agent. Antibacterial agent 100 shows promising activity with MIC values of 4, 4 and 8 μg/mL against Staphylococcus aureus, Candida albicans and Cryptococcus neoformans, respectively .
    Antibacterial agent 100
  • HY-163631

    Fungal Endogenous Metabolite Infection
    Antibacterial agent 218 (compound d28) is an orally active sterol 24-C-Methyltransferase inhibitor with the IC50 of 0.273 μM. Antibacterial agent 218 shows antifungal activity against the C.albicans SC5314 with the IC50 of 0.25 μg/mL .
    Antibacterial agent 218
  • HY-151439

    Fungal Infection
    Antifungal agent 41 (compound B01) is an antifungal agent. Antifungal agent 41 shows inhibitory effect on Candida albicans in virto and vivo. Antifungal agent 41 can be used for the research of invasive fungal infections .
    Antifungal agent 41
  • HY-161380

    Fungal Infection
    Antifungal agent 96 (Compound WZ-2) is an antifungal agent with good blood-brain barrier permeability and brain penetration. Antifungal agent 96 inhibits the growth of C. neoformans H99 and C. albicans 0304103 with MIC values of 0.016 and 32 μg/mL, respectively .
    Antifungal agent 96
  • HY-P3916

    Bacterial Infection Inflammation/Immunology
    GVLSNVIGYLKKLGTGALNAVLKQ is an antimicrobial peptide with 24-amino acid. GVLSNVIGYLKKLGTGALNAVLKQ can potentially form α-helix. GVLSNVIGYLKKLGTGALNAVLKQ (PGQ) has activity against Gram-negative, Gram-positive bacteria and the yeast Candida albicans .
    GVLSNVIGYLKKLGTGALNAVLKQ
  • HY-N13025

    Verrucarin L acetate

    Fungal Infection
    8-Acetylverrucarin L (Verrucarin L acetate) is a mycotoxin, which exhibits antitumor and antimicrobial activities. 8-Acetylverrucarin L exhibits cytotoxicity to cancer cells HCT116 and A2780S, with IC100 of 9.77 and 9.77 ng/mL. 8-Acetylverrucarin L exhibits antifungal activity against Saccharomyces cerevisiae, Candida albicans and Geotrichum candidum .
    8-Acetylverrucarin L
  • HY-P10538

    Bacterial Fungal Infection
    Balteatide is an antimicrobial peptide, which can be found in skin secretion of Phyllomedusa baltea. Balteatide inhibits the gram-positive Staphylococcus aureus (MIC=435 μM), the gram-negative Escherichia coli (MIC=109 μM), and Candida albicans (MIC=27 μM). Balteatide lacks hemolytic activity (at 512 mg/L) and myotropic activity .
    Balteatide
  • HY-162418

    Bacterial Fungal Infection
    Antibacterial agent 203 (Compound 5h) has antibacterial and antifungal activity. Antibacterial agent 203 has potent antifungal activity against C. albicans, with a MIC of 3.90 μg/mL. Antibacterial agent 203 has antimicrobial activity on healthy mouse fibroblast cells (L929), with an IC50 of 75.96 μM .
    Antibacterial agent 203
  • HY-147919

    Fungal Infection
    Antifungal agent 33 (compound 4e) is a potent antifungal agent. Antifungal agent 33 exhibits remarkable antifungal activity against C. albicans, with a MIC of 16 μg/mL. Antifungal agent 33 shows potent inhibitory activity against Lanosterol 14α-demethylase (CYP51), with an IC50 of 0.19 μg/mL .
    Antifungal agent 33
  • HY-124701

    Fungal Infection
    Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay. Filastatin inhibits fungal adhesion to polystyrene and human cells, the yeast-to-hyphal morphological transition, induction of the hyphal-specific HWP1 promoter. Filastatin has potent antifungal effect .
    Filastatin
  • HY-N7626

    Fungal Glucosidase Infection
    Eleutherol is a naphthalene isolated from E. americana with antifungal activities . Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL . Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM .
    Eleutherol
  • HY-19404

    CS-758; R-120758

    Fungal Infection
    Embeconazole (CS-758; R-120758) is an antifungal agent against Candida albicans, Cryptococcus neoformans, Aspergillus fumigatus and Aspergillus flavus, with MICs of 8, 16, 63 and 250 μM, respectively .
    Embeconazole
  • HY-156090

    Mitochondrial Metabolism Fungal Infection
    PK-10 is a synergistic antibacterial agent of Fluconazole (HY-B0101) and has strong antifungal activity against a variety of Fluconazole-resistant Candida albicans strains. PK-10 combined with Fluconazole can inhibit hyphae formation and induce the accumulation of reactive oxygen species. It further causes damage to mitochondrial membrane potential, reduces intracellular ATP content, and leads to mitochondrial dysfunction .
    PK-10
  • HY-169165

    Fungal Infection
    14α-Demethylase-IN-1 (compound 2e) is a 14α-demethylase inhibitor and can be used as an antifungal agent. 14α-Demethylase-IN-1 (48 h) exhibits MIC50 values of 2.47 μM, 1.23 μM, 19.70 μM, and 19.70 μM for C. albicans, C. parapsilosis, C. krusei, and C. glabrata, respectively .
    14α-Demethylase-IN-1

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