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co-factor

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155

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2

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1

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6

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6

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1

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7

Click Chemistry

6

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100196
    Pyrroloquinoline quinone
    4 Publications Verification

    PQQ; Methoxatin

    Endogenous Metabolite Inflammation/Immunology
    Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .
    Pyrroloquinoline quinone
  • HY-100196A
    Pyrroloquinoline quinone disodium salt
    4 Publications Verification

    PQQ disodium salt; Methoxatin disodium salt

    Endogenous Metabolite Inflammation/Immunology
    Pyrroloquinoline quinone disodium salt, a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function .
    Pyrroloquinoline quinone disodium salt
  • HY-B2246
    L-Carnitine hydrochloride
    15+ Cited Publications

    (R)-Carnitine hydrochloride; Levocarnitine hydrochloride

    Endogenous Metabolite Metabolic Disease Cancer
    L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .
    L-Carnitine hydrochloride
  • HY-B0511S

    Vitamin B7 d2-1; Vitamin H d2-1; D-Biotin d2-1

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Biotin-d2-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
    Biotin-d2-1
  • HY-B0511S1

    rel-Vitamin B7-d4; rel-Vitamin H-d4; rel-D-Biotin-d4

    Endogenous Metabolite Metabolic Disease
    rel-Biotin-d4 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
    rel-Biotin-d4
  • HY-100196S1

    PQQ-13C3 sodium; Methoxatin-13C3 sodium

    Endogenous Metabolite Inflammation/Immunology
    Pyrroloquinoline quinone-13C3 (sodium) is an isotope of Pyrroloquinoline quinone. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .
    Pyrroloquinoline quinone-13C3 sodium
  • HY-100196R

    Endogenous Metabolite Inflammation/Immunology
    Pyrroloquinoline quinone (Standard) is the analytical standard of Pyrroloquinoline quinone. This product is intended for research and analytical applications. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .
    Pyrroloquinoline quinone (Standard)
  • HY-B0511S2

    Vitamin B7-d2; Vitamin H-d2; D-Biotin-d2

    Endogenous Metabolite Metabolic Disease
    Biotin-d2 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
    Biotin-d2
  • HY-B2246R

    Endogenous Metabolite Metabolic Disease Cancer
    L-Carnitine (hydrochloride) (Standard) is the analytical standard of L-Carnitine (hydrochloride). This product is intended for research and analytical applications. L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .
    L-Carnitine (hydrochloride) (Standard)
  • HY-140656F

    Fluorescent Dye Others
    Biotin-PEG-Biotin (MW 20000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity.
    Biotin-PEG-Biotin (MW 20000)
  • HY-147207C

    Liposome Others
    Phospholipid-PEG-Biotin (MW 5000) is a phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic “head” and two hydrophobic “tails”; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein .
    Phospholipid-PEG-Biotin (MW 5000)
  • HY-147207A

    Liposome Others
    Phospholipid-PEG-Biotin (MW 2000) is a Biotin labeled phospholipid PEG derivative, can be used for modify liposome and cells surface, and pancreatic islets for cell transplantation. Phospholipid is a class of lipid containing a hydrophilic “head” and two hydrophobic “tails”; PEG is a hydrophilic and water-soluble polymer with low toxicity; Biotin is an enzyme co-factor, can be used for labeling protein .
    Phospholipid-PEG-Biotin (MW 2000)
  • HY-129056

    Thrombin Cardiovascular Disease
    Melagatran is a direct and orally active inhibitor of thrombin, without interacting with any other enzymes in the coagulation cascade or fibrinolytic enzymes aside from thrombin. Melagatran does not require endogenous co-factors for its antithrombin effect and may help to alleviate some of the damaging effects of endotoxemia . Melagatran has the potential to provide a rational approach in the prevention of arterial occlusion .
    Melagatran
  • HY-B1746

    Endogenous Metabolite Neurological Disease
    Pyridoxamine 5′-phosphate is the active form of vitamin B6 bound to phosphoric acid. Pyridoxamine 5′-phosphate is the aminated form of pyridoxal 5'-phosphate hydrate (HY-W011727A) and as co-factor of a variety of enzymes central metabolite, potent antioxidant, vitamin B6 vitamer and enzyme substrate. Pyridoxamine 5′-phosphate can be interconverted with pyridoxal 5'-phosphate hydrate .
    Pyridoxamine 5′-phosphate
  • HY-B0399
    L-Carnitine
    15+ Cited Publications

    (R)-Carnitine; Levocarnitine

    Endogenous Metabolite Neurological Disease Cancer
    L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .
    L-Carnitine
  • HY-B2246S

    (R)-Carnitine-d9 chloride; Levocarnitine-d9 chloride

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    L-Carnitine-d9 (chloride)e is the deuterium labeled L-Carnitine chloride. L-Carnitine chloride, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine chloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine chloride is an antioxidant. L-Carnitine chloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3].
    L-Carnitine-d9 chloride
  • HY-B0399G

    (R)-Carnitine; Levocarnitine

    Endogenous Metabolite Neurological Disease Cancer
    L-Carnitine (GMP) is L-Carnitine (HY-B0399) produced by using GMP guidelines. L-Carnitine, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .
    L-Carnitine
  • HY-B0399R

    Endogenous Metabolite Neurological Disease Cancer
    L-Carnitine (Standard) is the analytical standard of L-Carnitine. This product is intended for research and analytical applications. L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .
    L-Carnitine (Standard)
  • HY-147206C

    Fluorescent Dye Others
    Biotin-PEG-Alk (MW 3400) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 3400) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin-PEG-Alk (MW 3400)
  • HY-147206A

    Fluorescent Dye Others
    Biotin-PEG-Alk (MW 1000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 1000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin-PEG-Alk (MW 1000)
  • HY-147206E

    Fluorescent Dye Others
    Biotin-PEG-Alk (MW 10000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 10000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin-PEG-Alk (MW 10000)
  • HY-147206B

    Fluorescent Dye Others
    Biotin-PEG-Alk (MW 2000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 2000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin-PEG-Alk (MW 2000)
  • HY-147206F

    Fluorescent Dye Others
    Biotin-PEG-Alk (MW 20000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; Alk (Alkyne), acyclic (branched or unbranched) aliphatic hydrocarbon, can react with azido, which improve the efficiency of biotin binding targets. Biotin-PEG-Alk (MW 20000) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Biotin-PEG-Alk (MW 20000)
  • HY-W250928D

    Fluorescent Dye Others
    Biotin-PEG-azide (MW 3400) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Biotin-PEG-azide (MW 3400)
  • HY-W250928C

    Fluorescent Dye Others
    Biotin-PEG-azide (MW 2000) is a biotin labeled PEG derivative. Biotin is an enzyme co-factor, can be used for labeling protein; PEG is a hydrophilic and water-soluble polymer with low toxicity; azide, is a moderately good leaving group, can react with alkyne by Cu-catalyzation, which improve the efficiency of biotin binding targets. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Biotin-PEG-azide (MW 2000)
  • HY-107383

    (Rac)-Sapropterin

    NO Synthase Endogenous Metabolite Inflammation/Immunology
    Tetrahydrobiopterin ((Rac)-Sapropterin) is a cofactor of the aromatic amino acid hydroxylases enzymes and also acts as an essential cofactor for all nitric oxide synthase (NOS) isoforms.
    Tetrahydrobiopterin
  • HY-F0003A
    NADPH tetracyclohexanamine
    5+ Cited Publications

    Ferroptosis Endogenous Metabolite Others
    NADPH tetracyclohexanamine is a ubiquitous cofactor and biological reducing agent.
    NADPH tetracyclohexanamine
  • HY-107383R

    NO Synthase Endogenous Metabolite Inflammation/Immunology
    Tetrahydrobiopterin (Standard) is the analytical standard of Tetrahydrobiopterin. This product is intended for research and analytical applications. Tetrahydrobiopterin ((Rac)-Sapropterin) is a cofactor of the aromatic amino acid hydroxylases enzymes and also acts as an essential cofactor for all nitric oxide synthase (NOS) isoforms.
    Tetrahydrobiopterin (Standard)
  • HY-102015

    L-Biopterin

    NO Synthase Endogenous Metabolite Neurological Disease Cancer
    6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor.
    6-Biopterin
  • HY-14614A

    S-Adenosyl methionine chloride dihydrochloride; Ademetionine chloride dihydrochloride; AdoMet chloride dihydrochloride

    Endogenous Metabolite Metabolic Disease Cancer
    S-Adenosyl-L-methionine (S-Adenosyl methionine) chloride dihydrochloride is a methyl donor and cofactor .
    S-Adenosyl-L-methionine chloride dihydrochloride
  • HY-125954B

    Biochemical Assay Reagents Metabolic Disease
    UDP-galacturonic acid trisodium is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase .
    UDP-galacturonic acid trisodium
  • HY-N0111
    Coenzyme Q10
    5 Publications Verification

    coQ10; Ubiquinone-10; Ubidecarenone

    Endogenous Metabolite Reactive Oxygen Species Ferroptosis Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
    Coenzyme Q10
  • HY-145503

    Drug Derivative Metabolic Disease
    Decanoyl-L-carnitine chloride is an ester derivative of L-carnitine, which is an important cofactor of fatty acid metabolism .
    Decanoyl-L-carnitine chloride
  • HY-160653

    Bacterial Infection
    JPL is a InhA-cofactor-ligand 3FNG inhibitor, and can be used for study of tuberculosis .
    JPL
  • HY-143346

    Ligands for E3 Ligase Cancer
    CCW16 is a cofactor for the synthesis of protein degraders, such as PROTACs CCW 28-3 (HY-156774).
    CCW16
  • HY-171016

    Endogenous Metabolite Neurological Disease Cancer
    D-Biopterin is an enantiomer of L-Biopterin (HY-102015). L-Biopterin, a pterin derivative, is a NO synthase cofactor .
    D-Biopterin
  • HY-P2969

    Endogenous Metabolite Metabolic Disease
    Complement factor I is a serine protease that downregulates complement activity in the fluid phase and/or on cell surfaces in conjunction with one of its cofactors, factor H (FH), complement receptor 1 (CR1/CD35), C4 binding protein (C4BP) or membrane cofactor protein (MCP/CD46) .
    Complement factor I
  • HY-P3186

    Endogenous Metabolite Metabolic Disease
    Glucose dehydrogenase, recombinant Microorganisms is a oxidoreductase. Glucose dehydrogenase (GDH) catalyzes the oxidation of β-D-glucose to β-D-glucono-1,5-lactone with simultaneous reduction of the cofactor NADP + to NADPH or, to a lesser extent, NAD + to NADH. Glucose dehydrogenase (GDH) accepts both NAD + and NADP + as cofactors and can be used for the regeneration of NADH and NADPH .
    Glucose dehydrogenase, recombinant Microorganisms
  • HY-N0680S1

    Thiamine chloride-d3 hydrochloride; Vitamin B1-d3 hydrochloride

    Isotope-Labeled Compounds Endogenous Metabolite Apoptosis HBV Neurological Disease
    Thiamine-d3 (hydrochloride) is the deuterium labeled Thiamine hydrochloride. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
    Thiamine-d3 hydrochloride
  • HY-N0680S2

    Thiamine chloride-d4 hydrochloride; Vitamin B1-d4 hydrochloride

    Endogenous Metabolite Apoptosis HBV Neurological Disease
    Thiamine-d4 (hydrochloride) is deuterium labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
    Thiamine-d4 hydrochloride
  • HY-B1654
    Flavin adenine dinucleotide
    2 Publications Verification

    FAD

    Endogenous Metabolite Cardiovascular Disease
    Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
    Flavin adenine dinucleotide
  • HY-N0680S

    Endogenous Metabolite Neurological Disease
    Thiamine monochloride- 13C4 (hydrochloride) is the deuterium labeled Thiamine hydrochloride. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
    Thiamine monochloride-13C hydrochloride
  • HY-B1654A

    FAD disodium salt; FAD-Na2

    Endogenous Metabolite Cardiovascular Disease
    Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
    Flavin adenine dinucleotide disodium salt
  • HY-112790
    Adenosylcobalamin
    1 Publications Verification

    coenzyme B12; cobamamide; AdoCbl

    Endogenous Metabolite Metabolic Disease
    Adenosylcobalamin (Coenzyme B12;Cobamamide;AdoCbl) is an active form of Vitamin B12 which is a cofactor for methylmalonyl CoA mutase
    Adenosylcobalamin
  • HY-N0680S3

    Thiamine chloride-13C3 hydrochloride; Vitamin B1-13C3 hydrochloride

    Isotope-Labeled Compounds Endogenous Metabolite Apoptosis HBV Neurological Disease
    Thiamine- 13C3 (hydrochloride) is the 13C-labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
    Thiamine-13C3 hydrochloride
  • HY-14769A

    5,10-Methylenetetrafolate calcium; ANX-510

    Endogenous Metabolite Cancer
    Folitixorin calcium is a cofactor and an analog of leucovorin. Folitixorin calcium is a promising agent for modulation of 5-FU cytotoxicity in adjuvant cancer research .
    Folitixorin calcium
  • HY-18733
    Lipoic acid
    5+ Cited Publications

    (R)-(+)-α-Lipoic acid; R-(+)-Thioctic acid

    Mitochondrial Metabolism Endogenous Metabolite Reactive Oxygen Species Inflammation/Immunology Cancer
    Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid.
    Lipoic acid
  • HY-W013046

    PRPP pentasodium

    Endogenous Metabolite Others
    Phosphoribosyl pyrophosphate (PRPP) pentasodium is an important metabolite required in the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, and the cofactors NAD and NADP .
    Phosphoribosyl pyrophosphate pentasodium
  • HY-E70522

    DHFR

    Others Others
    Dihydrofolate reductase is a key enzyme in folate metabolism and, therefore, in the production of thymidine. Its role in thymidine biosynthesis is the reduction of dihydrofolate to tetrahydrofolate using the cofactor NADPH .
    Dihydrofolate reductase
  • HY-N0680R

    Thiamine chloride (hydrochloride) (Standard); Vitamin B1 (hydrochloride) (Standard)

    Bacterial Endogenous Metabolite HBV Apoptosis Neurological Disease
    Thiamine (hydrochloride) (Standard) is the analytical standard of Thiamine (hydrochloride). This product is intended for research and analytical applications. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
    Thiamine (hydrochloride) (Standard)

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