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Results for "

immunomodulatory activities

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (1) Aminoacyl-tRNA Synthetase (1) AMPK (2) Antibiotic (6) Antibody-Drug Conjugates (ADCs) (1) Apoptosis (20) Autophagy (8) Bacterial (11) Bcl-2 Family (1) Biochemical Assay Reagents (1) c-Fms (1) Calcium Channel (2) CDK (1) Cholinesterase (ChE) (2) Complement System (2) COX (1) Cyclin G-associated Kinase (GAK) (1) DNA-PK (1) E1/E2/E3 Enzyme (2) Endogenous Metabolite (4) Enterovirus (1) Epigenetic Reader Domain (1) ERK (4) Ferroptosis (1) Fungal (4) Glutathione S-transferase (1) GSK-3 (1) HBV (1) HCV (1) HDAC (1) HIV (1) HSP (2) HSV (2) IFNAR (1) Influenza Virus (1) Integrin (1) Interleukin Related (7) JNK (1) LPL Receptor (2) MAGL (1) MEK (1) Microtubule/Tubulin (1) Molecular Glues (2) mTOR (1) Necroptosis (1) NF-κB (5) NO Synthase (4) NOD-like Receptor (NLR) (2) Nucleoside Antimetabolite/Analog (11) P-glycoprotein (1) p38 MAPK (1) Parasite (1) PD-1/PD-L1 (1) Phosphodiesterase (PDE) (1) PKC (1) Prostaglandin Receptor (1) Raf (1) RAR/RXR (1) Ras (1) Reactive Oxygen Species (3) Salt-inducible Kinase (SIK) (1) Serotonin Transporter (3) SOD (1) Tau Protein (1) Tie (1) TNF Receptor (1) VEGFR (1) Virus Protease (2)
By Research Areas:	Cancer (31) Cardiovascular Disease (3) Endocrinology (4) Infection (19) Inflammation/Immunology (58) Metabolic Disease (4) Neurological Disease (10)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Nucleosides and their Analogs (11)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-104069

S1P1 agonist 1	LPL Receptor	Inflammation/Immunology
S1P1 Agonist 1 is a S1P1 agonist with immunomodulatory activities.

HY-66012

Proparacaine Hydrochloride 1 Publications Verification Proxymetacaine Hydrochloride	Apoptosis	Inflammation/Immunology
Proparacaine Hydrochloride (Proxymetacaine Hydrochloride) is a derivative of lidocaine (HY-B0185), with immunomodulatory effect and glucocorticomimetic activity .

HY-75247

Coumaran 2 Publications Verification 2,3-Dihydrobenzofuran	Cholinesterase (ChE) Endogenous Metabolite Parasite	Infection Neurological Disease Inflammation/Immunology
Coumaran (2,3-Dihydrobenzofuran) is an AChE inhibitor with antileishmanial activity. Coumaran may acquire antiparasitic capabilities through activation of macrophages and exert immunomodulatory activity. Coumaran can be used as a biopesticide. .

HY-P10639A

C5aR2 agonist P32 acetate	Complement System	Inflammation/Immunology
C5aR2 agonist P32 (Ac-RHYPYWR-OH) acetate is a C5aR2-selective agonist. C5aR2 agonist P32 acetate has been shown to elicit multiple immunomodulatory activities, both by down-regulating the C5aR1-mediated cell signalling, and acting in a C5aR1-independent fashion, in vitro and in vivo .

HY-N10084

Cordifolioside A	Others	Inflammation/Immunology
Cordifolioside A is a natural phenyl propanoid glycoside with immunomodulatory activity .

HY-N2965

Bryonolic acid	NO Synthase	Neurological Disease Inflammation/Immunology Cancer
Bryonolic acid is an active triterpenoid compound with immunomodulatory, anti-inflammatory, antioxidant and anticancer activities .

HY-123590

BC12-4	Interleukin Related	Inflammation/Immunology
BC12-4 is a potent IL-2 secretion inhibitor with immunomodulatory activity .

HY-N9369

Verbascose	Others	Inflammation/Immunology
Verbascose, an alacto-oligosac-charides (GOS), has potent immunostimulatory activity. Verbascose acts as a potential natural immunomodulatory agent .

HY-P3917

LfcinB (20–30)	Bacterial	Infection
LfcinB (20–30) is a fragment of bovine lactoferricin. LfcinB (20–30) has bactericidal, antifungal, antiparasitic, antitumor, antiviral and immunomodulatory activities.

HY-129577

Aplysin	Necroptosis	Inflammation/Immunology Cancer
Aplysin is a brominated sesquiterpene with an isoprene backbone that exhibits hepatoprotective, immunomodulatory, and antitumor activities. Aplysin effectively prevents spontaneous pancreatic necrosis and inflammatory responses in NOD mice .

HY-N0017

Bergenin 4 Publications Verification Cuscutin	NF-κB Autophagy Apoptosis Bacterial Fungal Virus Protease	Infection Inflammation/Immunology Cancer
Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties .

HY-14801

Sivifene A-007	Others	Inflammation/Immunology Cancer
Sivifene (A-007) is a triaryl hydrazone. Sivifene has anticancer activity and immunomodulatory effects. Sivifene regulates immune regulation by upregulating CD45 T lymphocyte surface receptors .

HY-66012R

Proparacaine Hydrochloride (Standard)	Apoptosis	Inflammation/Immunology
Proparacaine (Hydrochloride) (Standard) is the analytical standard of Proparacaine (Hydrochloride). This product is intended for research and analytical applications. Proparacaine Hydrochloride (Proxymetacaine Hydrochloride) is a derivative of lidocaine (HY-B0185), with immunomodulatory effect and glucocorticomimetic activity .

HY-153832

MSU-42011	RAR/RXR NO Synthase	Cancer
MSU-42011 is an orally active retinoid X receptor (RXR) agonist. MSU-42011 inhibits the iNOS activity and reduces the expression of p-ERK protein. MSU-42011 has immunomodulatory and antitumor activity .

HY-P5729

LL-25	Fungal	Infection
LL-25 is a fragment of LL-37 (HY-P1222) but devoid of the immunomodulatory properties of LL-37. LL-25 has antifungal and candidacidal activity .

HY-113471

Perillic acid	Apoptosis HSV	Infection Inflammation/Immunology Cancer
Perillic acid is the metabolite of Perillyl alcohol (HY-N7000). Perillic acid induces lung cancer cell cycle arrest and apoptosis. Perillic acid shows anti-HSV-1 and immunomodulatory activities .

HY-106765A

Thymotrinan TFA RGH-0205 TFA; TP3 TFA		Inflammation/Immunology
Thymotrinan (RGH-0205) TFA is a biologically active fragment of the naturally occurring thymus hormone thymopoietin and a immunomodulating peptide. Thymotrinan TFA exerts similar immunomodulatory activities to TP5 and to affect humoral as well as cellular responses .

HY-P5842

Citrullinated LL-37 3cit	Bacterial Influenza Virus	Infection
Citrullinated LL-37 3cit is a host defense peptide (HDP) with broad immunomodulatory and antimicrobial activities. Citrullinated LL-37 3cit exhibits direct antiviral effects against human rhinoviruses (HRV) .

HY-N7696

Physalin F	Apoptosis	Inflammation/Immunology
Physalin F is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBMC, decreasing the spontaneous proliferation and cytokine production caused by Human T-lymphotropic virus type 1 (HTLV-1) infection .

HY-156089

Triptoquinone H	Others	Inflammation/Immunology Cancer
Triptoquinone H is a class of natural product isolated from traditional Chinese medicine Tripterygium hypoglaucu. Triptoquinone H has strong cytotoxic, immunomodulatory and anti-inflammatory activities. Triptoquinone H can be used for cancer or inflammatory diseases research .

HY-N0206

Ardisiacrispin A Deglucocyclamin; LTS-4; Saxifragifolin B	Antibiotic	Cancer
Ardisiacrispin A (Deglucocyclamin) is a common triterpenoid saponin from Ardisia species. Ardisiacrispin A has similar biological properties with some triterpenoid saponins in A. crenata which is one of the species of genus Ardisia and exhibits cytotoxic effect on tumor cells, immunomodulatory and antiviral activities .

HY-N12714

Interiorin C	Others	Others
Interiorin C is the key active ingredient and key bioactivity marker in Schisandra chinensis (K. Interiorin) that is directly related to the improvement of hematopoietic function. Modern pharmacological research attributes Schisandra chinensis's blood-tonifying effects to its antioxidant and immunomodulatory activities .

HY-100507

Avadomide Maximum Cited Publications 6 Publications Verification CC 122	E1/E2/E3 Enzyme Apoptosis Molecular Glues NF-κB	Inflammation/Immunology Cancer
Avadomide is an orally active cereblon modulator. Avadomide modulates cereblon E3 ligase activity, inhibits NF-κB pathway, arrests the cell cycle at G1 phase, and thus induces apoptosis in cancer cell PDAC. Avadomide exhibits potent antitumor and immunomodulatory activities .

HY-W250978

Ovalbumins 2 Publications Verification	Endogenous Metabolite	Infection Cardiovascular Disease Inflammation/Immunology Cancer
Ovalbumins (OVA), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues .

HY-N0017R

Bergenin (Standard)	NF-κB Autophagy Apoptosis Bacterial Fungal Virus Protease	Infection Inflammation/Immunology Cancer
Bergenin (Standard) is the analytical standard of Bergenin. This product is intended for research and analytical applications. Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties .

HY-129393

Etrumadenant Maximum Cited Publications 6 Publications Verification AB928	Adenosine Receptor	Inflammation/Immunology Cancer
Etrumadenant (AB928) is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist. Etrumadenant relieves adenosine-mediated immune suppression. Etrumadenant has immunomodulatory and antitumor activities .

HY-121370

a-D-Galactose	HIV Endogenous Metabolite	Others
α-D-Galactose is a non-starch polysaccharide isolated from the bulb tissues of Lilium davidii var. unicolor Salisb. α-D-Galactose has anti-oxidation properties, anti-tumour activities, immunomodulatory effects and anti-HIV functions .

HY-159159

MS-II-124	NOD-like Receptor (NLR)	Inflammation/Immunology
MS-II-124 is an effective and selective NLRP3 inhibitor (IC₅₀=0.12 μM) with anti-inflammatory and immunomodulatory activities, which can be used in the research of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) .

HY-P2170

XMP-629 XOMA-629	Antibiotic Bacterial	Infection Inflammation/Immunology
XMP-629 (XOMA-629), a cationic α-helical peptide, is a potent endotoxin inhibitor. XMP-629 exhibits broad-spectrum antimicrobial activity via an immunomodulatory mechanism. XOMA 629 has antimicrobial activity against Propionibacterium acnes, Staphylococcus aureus and Streptococcus pyogenesand .

HY-N9337

Amaroswerin	NO Synthase	Metabolic Disease Inflammation/Immunology Cancer
Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC₅₀ value of 5.42 μg/mL in RAW264.7 cells .

HY-P3161

Lactoferrin	HSV	Infection Inflammation/Immunology Cancer
Lactoferrin is a substance released by neutrophils. Lactoferrin is an orally active multifunctional iron binding glycoprotein. Lactoferrin prevents cell adhesion, growth and spreading of cell colonies. Lactoferrin also has antiviral activity and inhibits microbial and viral adhesion and entry into host cells. Besides, Lactoferrin has anti-inflammatory, immunomodulatory, and anti-cancer activities .

HY-112575

Tiazotic acid	Others	Infection Cardiovascular Disease Inflammation/Immunology
Tiazotic acid is a metabolic agent that has immunomodulatory, anti-inflammatory, antioxidant, anti-ischemic, cardio- and endothelioprotective, antiplatelet, hepatoprotective activities. Tiazotic acid increases the levels of eNOS. Tiazotic acid also reduces the level of D-dimer in the blood, which reduces the risks of heart attacks and strokes in post-COVID syndrome .

HY-158166

DNA-PK-IN-13	DNA-PK	Inflammation/Immunology Cancer
DNA-PK-IN-13 (Compound SK10) is a DNA-PK inhibitor that exhibits potent inhibitory activity (IC₅₀= 0.11 nM). DNA-PK-IN-13 regulates tumor cell proliferation by decreasing the expression level of γH2A.X and enhancing the sensitivity of tumor cells to chemotherapeutic agents. DNA-PK-IN-13 is suitable for oncology studies .

HY-B0944

Pidotimod 1 Publications Verification	Bacterial	Inflammation/Immunology
Pidotimod is an orally active dipeptide immunostimulant with immunomodulatory properties on the adaptive and the innate immune responses. Pidotimod increases macrophage activity and humoral immune functions. Pidotimod can be used for the research of chronic bronchitis, chronic obstructive pulmonary disease (COPD), bronchiectasis, and chronic idiopathic urticaria,et al .

HY-100507A

Avadomide hydrochloride CC 122 hydrochloride	E1/E2/E3 Enzyme Apoptosis Molecular Glues NF-κB	Inflammation/Immunology Cancer
Avadomide hydrochloride (CC 122 hydrochloride) is the hydrochloride form of Avadomide (HY-100507). Avadomide hydrochloride is an orally active cereblon modulator. Avadomide hydrochloride modulates cereblon E3 ligase activity, inhibits NF-κB pathway, arrests the cell cycle at G1 phase, and thus induces apoptosis in cancer cell PDAC. Avadomide hydrochloride exhibits potent antitumor and immunomodulatory activities .

HY-N0313

Euphol	MAGL Endogenous Metabolite	Inflammation/Immunology
Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC₅₀=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain .

HY-W094474

Lithium chloride hydrate 2 Publications Verification hydrate/monohydrateortrihydrate	GSK-3 Apoptosis	Infection Neurological Disease
Lithium chloride hydrate, an orally active mood stabilizer, is a potent virus inhibitor and effective immunomodulatory agent. Lithium chloride hydrate has antidepressant activity by inhibiting GSK3β and promoting neurogenesis. Lithium chloride hydrate alleviates cognition dysfunction and the symptoms of acute mania and depression. Lithium chloride hydrate can also be used for research of virus infection and Alzheimer's disease .

HY-162727

GCS-12	Interleukin Related IFNAR	Inflammation/Immunology Cancer
GCS-12 is a Th1/2-balanced sulfonamide glycolipid with improved interaction with CD1d. GCS-12 is an agonist for natural killer T (NKT) cell, that induces the secretion of cytokine IFN-γ and IL-4, and exhibits immunomodulatory and anti-tumor activities in mice .

HY-NP026

Spirulina C-phycocyanin C-phycocyaninfromporphyratenera	SOD Integrin	Inflammation/Immunology
Spirulina C-phycocyanin, a component of the light-harvesting phycobilisome complex in photosystem II, is a highly dominant chromoprotein in Spirulina. Spirulina C-phycocyanin can be detected by Raman spectral measurement. Spirulina C-phycocyanin has antioxidant, anti-inflammatory, antiplatelet, liver-protective and cholesterol-lowering effects .

HY-N0410

Daucosterol 5 Publications Verification Eleutheroside A; β-Sitosterol β-D-glucoside	Apoptosis Reactive Oxygen Species Autophagy	Inflammation/Immunology Cancer
Daucosterol is an orally active natural sterol compound, which has anti-inflammatory, anticancer and immunomodulatory activities. Daucosterol inhibits cancer cell proliferation by inducing autophagy through ROS-dependent manner. Daucosterol also inhibits colon cancer growth by inducing apoptosis, inhibiting cell migration and invasion and targeting caspase signalling pathway .

HY-18164

TASP0277308	LPL Receptor	Inflammation/Immunology
TASP0277308 is a highly selective S1P₁ antagonist. TASP0277308 possesses immunomodulatory activities, including lymphopenia, a block in T cell egress from the thymus, marginal zone B cell displacement, and the upregulation of CD69 expression on lymphocytes. TASP0277308 can be used for the research of collagen-induced arthritis in mice .

HY-W717504

Glucosylceramide, plant	Others
Glucosylceramide, plant is a plant-derived glycolipid with anti-inflammatory and immunomodulatory activities. Glucosylceramide, plant plays an important role in promoting cell proliferation and repair. Glucosylceramide, plant is widely used in skin care products to enhance skin barrier function. Glucosylceramide, plant has also been studied for improving nervous system health, showing potential neuroprotective effects.

HY-136571

GSK046 3 Publications Verification iBET-BD2	Epigenetic Reader Domain	Inflammation/Immunology
GSK046 (iBET-BD2) is a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC₅₀s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2) and 214 nM (BRDT BD2), respectively. GSK046 has immunomodulatory activity .

HY-P990782

Efzofitimod	Aminoacyl-tRNA Synthetase	Inflammation/Immunology
Efzofitimod is a splice variant of the aminoacyl-tRNA synthetase HARS1, which is fused with the Fc segment of a human antibody. Efzofitimod targets the neuronal phospholipid NRP2 (neuropilin-2) and has anti-inflammatory and immunomodulatory activities. Efzofitimod can downregulate the innate and adaptive immune responses in inflammatory disease states, suppressing indirect lung disease (ILD) .

HY-B0905

Tilmicosin 2 Publications Verification LY-177370; EL-870	Bacterial Antibiotic Apoptosis Calcium Channel	Infection Inflammation/Immunology
Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin has immunomodulatory and anti-inflammatory effects .

HY-B0905A

Tilmicosin phosphate 2 Publications Verification LY-177370 phosphate; EL-870 phosphate	Bacterial Antibiotic Apoptosis NO Synthase COX	Infection Inflammation/Immunology
Tilmicosin (LY-177370) phosphate is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin phosphate mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin phosphate is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin phosphate has immunomodulatory and anti-inflammatory effects .

HY-B1490

Imipramine hydrochloride 5 Publications Verification	Serotonin Transporter Apoptosis Autophagy	Neurological Disease Inflammation/Immunology Cancer
Imipramine hydrochloride is an orally active tertiary amine tricyclic antidepressant. Imipramine hydrochloride is a Fascin1 inhibitor with antitumor activities. Imipramine hydrochloride also inhibits serotonin transporter with an IC₅₀ value of 32 nM. Imipramine hydrochloride stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine hydrochloride shows neuroprotective and immunomodulatory effects .

HY-B1490A

Imipramine 5 Publications Verification	Serotonin Transporter Autophagy Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Imipramine is an orally active tertiary amine tricyclic antidepressant. Imipramine is a Fascin1 inhibitor with antitumor activities. Imipramine also inhibits serotonin transporter with an IC₅₀ value of 32 nM. Imipramine stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine shows neuroprotective and immunomodulatory effects .

HY-152980

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

HY-154046

4,6-Diamino-1-(2-deoxy-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine	Nucleoside Antimetabolite/Analog	Others
4,6-Diamino-1-(2-deoxy-beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects .

Cat. No.	Product Name	Type

HY-W250978

Ovalbumins 2 Publications Verification	Native Proteins
Ovalbumins (OVA), the main protein found in egg whites, have various biological activities such as anticancer, antihypertensive, antibacterial, antioxidant and immunomodulatory activities. Ovalbumins are the most abundant proteins synthesized in progesterone- or estrogen-treated fallopian tubes and are commonly used as markers to study hormone regulation of gene expression in tissues .

HY-P3161

Lactoferrin

Native Proteins

Lactoferrin is a substance released by neutrophils. Lactoferrin is an orally active multifunctional iron binding glycoprotein. Lactoferrin prevents cell adhesion, growth and spreading of cell colonies. Lactoferrin also has antiviral activity and inhibits microbial and viral adhesion and entry into host cells. Besides, Lactoferrin has anti-inflammatory, immunomodulatory, and anti-cancer activities .

HY-NP026

Spirulina C-phycocyanin C-phycocyaninfromporphyratenera	Native Proteins
Spirulina C-phycocyanin, a component of the light-harvesting phycobilisome complex in photosystem II, is a highly dominant chromoprotein in Spirulina. Spirulina C-phycocyanin can be detected by Raman spectral measurement. Spirulina C-phycocyanin has antioxidant, anti-inflammatory, antiplatelet, liver-protective and cholesterol-lowering effects .

HY-158226

Elastin Methacrylated

ElaMA

3D Bioprinting

Elastin Methacrylated (ElaMA) elastin recruits and modulates innate immune cells and accelerates angiogenesis at the wound site, thereby improving wound regeneration. Elastin Methacrylated attracts large numbers of neutrophils and primarily M2 macrophages to the wound and induces their penetration into the hydrogel. Elastin Methacrylated has excellent immunomodulatory effects, leading to superior angiogenesis, collagen deposition and dermal regeneration . Elastin Methacrylated needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity.
Application: cell culture, biological 3D printing, tissue engineering, etc.

Cat. No.	Product Name	Target	Research Area

HY-106765A

Thymotrinan TFA RGH-0205 TFA; TP3 TFA		Inflammation/Immunology
Thymotrinan (RGH-0205) TFA is a biologically active fragment of the naturally occurring thymus hormone thymopoietin and a immunomodulating peptide. Thymotrinan TFA exerts similar immunomodulatory activities to TP5 and to affect humoral as well as cellular responses .

HY-P10639

C5aR2 agonist P32	Complement System	Inflammation/Immunology
C5aR2 agonist P32 (Ac-RHYPYWR-OH) is a C5aR2-selective agonist. C5aR2 agonist P32 has been shown to elicit multiple immunomodulatory activities, both by down-regulating the C5aR1-mediated cell signalling, and acting in a C5aR1-independent fashion, in vitro and in vivo .

HY-P10639A

C5aR2 agonist P32 acetate	Complement System	Inflammation/Immunology
C5aR2 agonist P32 (Ac-RHYPYWR-OH) acetate is a C5aR2-selective agonist. C5aR2 agonist P32 acetate has been shown to elicit multiple immunomodulatory activities, both by down-regulating the C5aR1-mediated cell signalling, and acting in a C5aR1-independent fashion, in vitro and in vivo .

HY-P3917

LfcinB (20–30)	Bacterial	Infection
LfcinB (20–30) is a fragment of bovine lactoferricin. LfcinB (20–30) has bactericidal, antifungal, antiparasitic, antitumor, antiviral and immunomodulatory activities.

HY-P5729

LL-25	Fungal	Infection
LL-25 is a fragment of LL-37 (HY-P1222) but devoid of the immunomodulatory properties of LL-37. LL-25 has antifungal and candidacidal activity .

HY-106765

Thymotrinan RGH-0205; TP3	Peptides	Inflammation/Immunology
Thymotrinan (RGH-0205) is a biologically active fragment of the naturally occurring thymus hormone thymopoietin and a immunomodulating peptide. Thymotrinan exerts similar immunomodulatory activities to TP5 and to affect humoral as well as cellular responses .

HY-P5842

Citrullinated LL-37 3cit	Bacterial Influenza Virus	Infection
Citrullinated LL-37 3cit is a host defense peptide (HDP) with broad immunomodulatory and antimicrobial activities. Citrullinated LL-37 3cit exhibits direct antiviral effects against human rhinoviruses (HRV) .

HY-P2170

XMP-629 XOMA-629	Antibiotic Bacterial	Infection Inflammation/Immunology
XMP-629 (XOMA-629), a cationic α-helical peptide, is a potent endotoxin inhibitor. XMP-629 exhibits broad-spectrum antimicrobial activity via an immunomodulatory mechanism. XOMA 629 has antimicrobial activity against Propionibacterium acnes, Staphylococcus aureus and Streptococcus pyogenesand .

HY-P5843

Citrullinated LL-37 4cit	Enterovirus	Infection
Citrullinated LL-37 3cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 3cit lacks all antiviral activity at 10 μg/mL and retains some activity against HRV at 30 μg/mL. Citrullinated LL-37 3cit reduces the immunomodulatory activity of LL-37. Citrullinated LL-37 3cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

HY-P3206

Serum thymic factor Thymulin; Thymic factor	ERK	Neurological Disease Inflammation/Immunology Endocrinology
Serum thymic factor (Thymulin) is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases .

HY-P3206A

Serum thymic factor acetate Thymulin acetate; Thymic factor acetate	ERK	Neurological Disease Inflammation/Immunology Endocrinology
Serum thymic factor acetate (Thymulin acetate) is the acetate salt form of Serum thymic factor (HY-P3206). Serum thymic factor acetate is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor acetate stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor acetate protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor acetate exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor acetate can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases .

Cat. No.	Product Name	Target	Research Area

HY-P99389

Tesnatilimab	Inhibitory Antibodies	Inflammation/Immunology
Tesnatilimab is a human IgG4 monoclonal antibody that acts on the immune activating receptor NKG2D and has potential immunomodulatory and anti-inflammatory activity. Tesnatilimab can be used in the study of inflammatory bowel disease (IBD) .