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Bis-5,5-Nortrachelogenin 是从 Wikstroemia indica 根中分离得到的活性提取物。Bis-5,5-Nortrachelogenin 抑制脂多糖 (LPS) 和重组小鼠干扰素-γ (IFN-γ) 激活的小鼠巨噬细胞样细胞系 RAW 264.7 中一氧化氮 (NO) 的生成，IC50 值为 48.6 mM。

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amylases (1) Apoptosis (9) Bacterial (1) Bcl-2 Family (1) Caspase (2) COX (4) Endogenous Metabolite (1) Epigenetic Reader Domain (1) ERK (3) Fungal (1) Glucosidase (1) HDAC (1) Histone Acetyltransferase (1) HIV Protease (1) IFNAR (5) IKK (2) Indoleamine 2,3-Dioxygenase (IDO) (1) Influenza Virus (1) Interleukin Related (7) Isotope-Labeled Compounds (2) JAK (1) Keap1-Nrf2 (3) Lipoxygenase (1) Mitochondrial Metabolism (1) MyD88 (1) Na+/H+ Exchanger (NHE) (1) nAChR (1) NF-κB (19) NO Synthase (27) NOD-like Receptor (NLR) (2) p38 MAPK (2) PGE synthase (2) Phosphatase (1) Phosphodiesterase (PDE) (1) PI3K (2) PKC (1) PPAR (1) Pyroptosis (1) RANKL/RANK (2) Reactive Oxygen Species (3) STAT (1) TNF Receptor (10) Toll-like Receptor (TLR) (4)
By Research Areas:	Cancer (14) Cardiovascular Disease (3) Endocrinology (1) Infection (4) Inflammation/Immunology (76) Metabolic Disease (7) Neurological Disease (5)

By Targets:

Amylases (1)

Apoptosis (9)

Bacterial (1)

Bcl-2 Family (1)

Caspase (2)

COX (4)

Endogenous Metabolite (1)

Epigenetic Reader Domain (1)

ERK (3)

Fungal (1)

Glucosidase (1)

HDAC (1)

Histone Acetyltransferase (1)

HIV Protease (1)

IFNAR (5)

IKK (2)

Indoleamine 2,3-Dioxygenase (IDO) (1)

Influenza Virus (1)

Interleukin Related (7)

Isotope-Labeled Compounds (2)

JAK (1)

Keap1-Nrf2 (3)

Lipoxygenase (1)

Mitochondrial Metabolism (1)

MyD88 (1)

Na+/H+ Exchanger (NHE) (1)

nAChR (1)

NF-κB (19)

NO Synthase (27)

NOD-like Receptor (NLR) (2)

p38 MAPK (2)

PGE synthase (2)

Phosphatase (1)

Phosphodiesterase (PDE) (1)

PI3K (2)

PKC (1)

PPAR (1)

Pyroptosis (1)

RANKL/RANK (2)

Reactive Oxygen Species (3)

STAT (1)

TNF Receptor (10)

Toll-like Receptor (TLR) (4)

By Research Areas:

Cancer (14)

Cardiovascular Disease (3)

Endocrinology (1)

Infection (4)

Inflammation/Immunology (76)

Metabolic Disease (7)

Neurological Disease (5)

100

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N3171A

(+)-Nortrachelogenin Wikstromol	Apoptosis PI3K	Cancer
(+)-Nortrachelogenin (Wikstromol), a pharmacologically ligand from from wikstroemia indica, possesses antileukemic activity .

HY-N10120

Methylsyringin	Others	Inflammation/Immunology
Methylsyringin exhibits anti-inflammatory activity in the LPS-stimulated RAW264.7 cells.

HY-N2939

**Bis-5,5-Nortrachelogenin**	Others	Others
Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC₅₀ value of 48.6 mM .

HY-N13175

Panaxcerol B	NO Synthase	Cancer
Panaxcerol B is a monogalactosyl monoacylglyceride, with an IC₅₀ of 59.4 μM for NO production in LPS-stimulated RAW264.7 cells .

HY-N3548

Catalpalactone	NF-κB	Inflammation/Immunology
Catalpalactone has anti-inflammatory effect. Catalpalactone inhibits LPS-induced NO production and iNOS expression in RAW264.7 cells, and also inhibits IRF3, NF-κB, and *IFN-β/STAT-1* activation. Catalpalactone also inhibits dopamine biosynthesis by reducing tyrosine hydroxylase (TH) and aromatic-l-amino acid decarboxylase (AADC) activities .

HY-125495

Telmesteine	Others	Inflammation/Immunology
Telmesteine is an amucolitic agent. Telmesteine has anti-protease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used for research of inflammation, such as acute and chronic bronchitis and obstructive airways disease .

HY-N10111

Siegesbeckialide I	IKK	Inflammation/Immunology
Siegesbeckialide I most potently inhibits LPS-induced NO production in RAW264.7 murine macrophages by directly binding to IKKα/β.

HY-N9000

Loganic acid 6′-O-β-D-glucoside	TNF Receptor	Inflammation/Immunology
Loganic acid 6′-O-β-D-glucoside, a iridoidal glucoside, is isolated from the whole plant of Gentiana rhodantha (Gentianaceae). Loganic acid 6′-O-β-D-glucoside inhibits LPS-induced NO and TNF-α production in macrophage RAW264.7 cells .

HY-W573700

Methyl everninate	Others	Others
Methyl everninate is the major constituent of the deuterochloroform. Methyl everninate, rhodomollosides A and B are the derivatives of Methyl everninate, with cytotoxicity against RAW264.7 cells. Both of they shows inhibitory effects with a lipopolysaccharide (LPS)-stimulated murine macrophages RAW 264.7 cells model .

HY-153762

COX-2-IN-32	NO Synthase NF-κB COX	Inflammation/Immunology
COX-2-IN-32 (Compound 2f) is an iNOS and COX-2 inhibitor. COX-2-IN-32 decreases the expression of NF-κB. COX-2-IN-32 has anti-inflammatory activity by inhibits NO production in LPS-induced RAW264.7 macrophages (IC₅₀: 11.2 μM) .

HY-N2989

3-O-Acetyl-16α-hydroxydehydrotrametenolic acid	NO Synthase	Inflammation/Immunology
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid, an anti-inflammatory triterpenoid, inhibits NO production and iNOS expression in LPS-stimulated Raw264.7 cells .

HY-N11544

Inflexuside B	NO Synthase	Inflammation/Immunology
Inflexuside B, an abietane diterpenoid, can be isolated from the aerial parts of Isodon inflexus. Inflexuside B strongly inhibits lipopolysaccharide (LPS)-activated NO Synthase in RAW264.7 macrophages .

HY-N11548

Inflexuside A	NO Synthase	Inflammation/Immunology
Inflexuside A, an abietane diterpenoid, can be isolated from the aerial parts of Isodon inflexus. Inflexuside B strongly inhibits lipopolysaccharide (LPS)-activated NO production (NO Synthase) in RAW264.7 macrophages .

HY-N1912

Andropanolide	Others	Cancer
Andropanolide is a natural product that exerts cytotoxicity toward carcinoma cells and significantly inhibits the overproduction of nitric oxide (NO) in Lipopolysaccharides (HY-D1056) (LPS)-stimulated RAW264.7 macrophages .

HY-N12283

NF-κB-IN-13	NF-κB	Inflammation/Immunology
NF-κB-IN-13 (compound 12) can significantly inhibit LPS-induced NF-κB activation and NO production in RAW264.7 macrophages. NF-κB-IN-13 has anti-inflammatory effects .

HY-N13184

Giraldoid B	TNF Receptor	Inflammation/Immunology
Giraldoid B is an active ingredient that can be isolated from Girald Daphne Bark. Giraldoid B can inhibit LPS induced NO and b>TNF-α production in RAW264.7 and has anti-inflammatory activity .

HY-149671

Anti-inflammatory agent 63	Others	Inflammation/Immunology
Anti-inflammatory agent 63 is an anti-inflammatory agent that shows optimal inhibitory activity (EC₅₀ = 5.33±0.57 μM) against the production of nitric oxide (NO) induced by lipopolysaccharide (LPS) in RAW264.7 cells .

HY-N13138

Angulasaponin B	NO Synthase	Inflammation/Immunology
Angulasaponin B, a natural product, can be obtained from Vigna angularis. Angulasaponin B inhibits nitric oxide production in LPS-activated RAW264.7 macrophages with IC₅₀ values ranging from 13 μM to 24 μM .

HY-N12494

Diplacol	NO Synthase	Inflammation/Immunology
Diplacol is a geranylated flavanone that can be isolated from paulownia trees (Paulownia coreana UYEKI). Diplacol has anti-inflammatory activity. Diplacol inhibits NO production in LPS-stimulated Raw264.7 cells with an IC₅₀ value of 4.53 μM .

HY-N3171

*Nortrachelogenin* (-)-Wikstromol; (-)-Nortrachelogenin	Apoptosis	Cancer
Nortrachelogenin ((-)-Wikstromol) from Partrinia scabiosaefolia elicits an apoptotic response in Candida albicans .

HY-N12042

Taxamairin B	TNF Receptor PI3K Reactive Oxygen Species Interleukin Related	Inflammation/Immunology
Taxamairin B is a potent anti-inflammatory agent. Taxamairin B decreases proinflammatory cytokines (TNF-α, IL-1β and IL-6) expression and the production of NO and ROS in LPS-induced RAW264.7 cells. Taxamairin B exhibits significant protective effects in LPS-induced acute lung injury in mice .

HY-N8805

Nortrachelogenin-8'-O-β-glucoside	Others	Cancer
Nortrachelogenin-8'-O-β-glucoside is a natural product that can be isolated from the dried roots of Pulsatilla koreana. Nortrachelogenin-8'-O-β-glucoside inhibits cancer cell proliferation and reduces hormone dependence .

HY-N11657

Sanggenon A Sanggenone A	NF-κB Keap1-Nrf2	Inflammation/Immunology
Sanggenon A (Sanggenone A) exerts anti-inflammatory effects by regulating NF-κB and HO-1/Nrf2 signaling pathways in BV2 and RAW264.7 cells. Sanggenon A markedly inhibits the Lipopolysaccharide (LPS; HY-D1056)-induced production of nitric oxide .

HY-N13239

Dandelion Extract	Others	Inflammation/Immunology
Dandelion Extract is a dandelion extract, and its ingredients include: Flavone. Dandelion Extract can reduce LPS-induced inflammatory responses in RAW264.7 cells by regulating cell polarization and apoptosis. Dandelion Extract can also reduce CuSO₄-induced inflammatory response in zebrafish larvae. .

HY-147770

NF-κB-IN-6	NF-κB	Inflammation/Immunology
NF-κB-IN-6 (Compound 3d) is an anti-inflammatory agent through the mechanism of decreasing the protein expressions of iNOS and COX-2 by suppressing NF-κB signaling pathway. NF-κB-IN-6 inhibits NO production in LPS-induced RAW264.7 cells with an IC₅₀ of 23.1 μM .

HY-N0634

Cimifugin 1 Publications Verification Cimitin	NF-κB	Inflammation/Immunology
Cimifugin (Cimitin) is a bioactive component of Cimicifuga racemosa, a Chinese herb. Cimifugin suppresses allergic inflammation by reducing epithelial derived initiative key factors via regulating tight junctions . Cimifugin reduces the migration and chemotaxis of RAW264.7 cells and inhibits the release of inflammatory factors and activation of MAPKs and NF-κB signaling pathways induced by LPS .

HY-N12235

Sarglaroids F	Caspase	Inflammation/Immunology
Sarglaroids F (compound 6) is an anti-inflammatory agent isolated from the roots of Grass Coral. Sarglaroids F inhibits LPS/ATP-induced IL-1β release by affecting K+ efflux and reducing Caspase-1(P20) levels. Sarglaroids F is not cytotoxic to RAW264.7 cells .

HY-N2838

Alismol	NO Synthase	Inflammation/Immunology
Alismol is a natural sesquiterpene. Alismol shows promising inhibitory effects on INF-γ-induced nitric oxide production in murine macrophage RAW264.7 cells .

HY-164173

LPS-PG	Toll-like Receptor (TLR) MyD88	Inflammation/Immunology
LPS-PG is a lipopolysaccharide from Porphyromonas gingivalis (P. gingivalis). LPS-PG is an important virulence factor in the pathogenesis of periodontal disease and activates immune cells via Toll-like receptor 2 (TLR2), rather than the receptor for Escherichia coli (E. coli), Toll-like receptor 4 (TLR4). A lipoprotein from LPS-PG has been shown to be the major component responsible for TLR2-mediated cell activation .

HY-N1494

(+)-14-Deoxy-ε-caesalpin 14-Deoxy-ε-caesalpin	NO Synthase	Inflammation/Immunology
(+)-14-Deoxy-ε-caesalpin (14-Deoxy-ε-caesalpin), a cassane diterpenoid, inhibits nitric oxide (NO) production release of RAW 264.7 cells stimulated by Lipopolysaccharide (LPS) .

HY-N10062

Amakusamine	RANKL/RANK	Others
Amakusamine inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced formation of multinuclear osteoclasts with an IC₅₀ value of 10.5 μM in RAW264.7 cells.

HY-130787

Apterin	NO Synthase	Inflammation/Immunology
Apterin is a natural compound with anti-inflammatory activity. Apterin shows significantly inhibitory activity on NO production in RAW264.7 cells with an IC₅₀ value of 41.8 μM .

HY-N13160

Sanggenon F	Others	Metabolic Disease Inflammation/Immunology
Sanggenon F is a flavonoid compound derived from Morus alba var. multicaulis. It inhibits the differentiation of 3T3-L1 adipocytes and the production of nitric oxide (NO) in RAW264.7 cells induced by lipopolysaccharides (HY-D1056) and IFN-γ (IC₅₀ of 19 nM). Sanggenon F has potential application value in the fields of anti-inflammatory and metabolic diseases .

HY-161043

ECDD-S16	Pyroptosis	Inflammation/Immunology
ECDD-S16 is a potent inhibitor of pyroptosis. ECDD-S16 inhibits surface and endosomal TLR ligands activated pyroptosis in Raw264.7 cells .

HY-149647

HD-2a	Others	Inflammation/Immunology
HA-2a can inhibit the JAK2/STAT3 pathway via downregulates circDcbld2 expression in RAW264.7 cells .

HY-N2535

Coniferaldehyde 1 Publications Verification 4-Hydroxy-3-methoxycinnamaldehyde	Keap1-Nrf2 Apoptosis	Inflammation/Immunology
Coniferaldehyde (4-Hydroxy-3-methoxycinnamaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. Coniferaldehyde has antioxidant and anti-inflammatory activities .

HY-159516

Sabialimon P	NO Synthase TNF Receptor NF-κB COX Interleukin Related	Inflammation/Immunology
Sabialimon P (compound 16) is a NO release inhibitor (IC₅₀=18.12 μM) with anti-inflammatory activity. Sabialimon P significantly reduces the secretion of TNF-α, iNOS, IL-6 and NF-κB and inhibits the expression of COX-2 and NF-κB/p65 in RAW264.7 cells induced by LPS (HY-D1056) .

HY-N1695

Demethylregelin Regelin acid	NO Synthase	Inflammation/Immunology
Demethylregelin (Regelin acid), a triterpene, effectively reduces the expression of iNOS protein and subsequent nitric oxide production induced by lipopolysaccharide (HY-D1056) in RAW264.7 cells. Demethylregelin has anti-inflammatory activities .

HY-N11990

Nortrachelogenin 4'-O-β-gentiobioside	Others	Others
Nortrachelogenin 4'-O-β-gentiobioside (compound 20) is a lignan isolated from the aerial parts of Trachelospermius .

HY-149351

NF-κB-IN-10	NF-κB	Cardiovascular Disease
NF-κB-IN-10 (compound E1) is an NF-κB inhibitor that can improve heart failure by reducing oxidative stress and inflammation by regulating Nrf2/NF-κB signaling pathway. NF-κB-IN-10 inhibits LPS-induced NO production and expression of iNOS and COX-2 in RAW264.7 cells. NF-κB-IN-10 can be used in the research of cardiovascular diseases .

HY-N0634R

Cimifugin (Standard)	NF-κB	Inflammation/Immunology
Cimifugin (Standard) is the analytical standard of Cimifugin. This product is intended for research and analytical applications. Cimifugin (Cimitin) is a bioactive component of Cimicifuga racemosa, a Chinese herb. Cimifugin suppresses allergic inflammation by reducing epithelial derived initiative key factors via regulating tight junctions . Cimifugin reduces the migration and chemotaxis of RAW264.7 cells and inhibits the release of inflammatory factors and activation of MAPKs and NF-κB signaling pathways induced by LPS .

HY-N3392

Lethedoside A	NO Synthase	Inflammation/Immunology
Lethedoside A is a natural flavonoid that shows inhibitory activity for LPS-induced NO production in RAW 264.7 cells .

HY-N11988

Nortrachelogenin 5'-C-β-glucopyranoside	Others	Others
Nortrachelogenin 5'-C-β-glucopyranoside (compound 3) is a glycoside compound that can be isolated from the aerial parts of Trachelospermia vine .

HY-164361

2′-Hydroxy-2,3-dimethoxychalcone	NO Synthase	Inflammation/Immunology
α-Gracinoic acid is a Chalcone (HY-121054) derivative with anti-inflammatory activity. α-Gracinoic acid inhibits nitric oxide production catalyzed by inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS)-treated RAW 264.7 cells .

HY-N2620

Rutaevin	Reactive Oxygen Species	Inflammation/Immunology
Rutaevin is isolated from the fruits of Euodia rutaecarpa. Rutaevin inhibits NO production in LPS-induced RAW 264.7 macrophages .

HY-N9337

Amaroswerin	NO Synthase	Metabolic Disease Inflammation/Immunology Cancer
Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC₅₀ value of 5.42 μg/mL in RAW264.7 cells .

HY-155820

Anti-inflammatory agent 54	NF-κB NO Synthase TNF Receptor Interleukin Related	Inflammation/Immunology
Anti-inflammatory agent 54 (compound 9c) is a derivative of Coixol and has anti-inflammatory activity. Anti-inflammatory agent 54 inhibits the NF-κB pathway and downregulates the expression of iNOS, TNF-α, IL-6 and IL-1β. Anti-inflammatory agent 54 inhibits LPS-induced nitric oxide (NO) production in RAW264.7 macrophages (IC₅₀: 2.4 μM) and exerts in vivo anti-inflammatory activity in a mouse auricular edema model .

HY-155821

Anti-inflammatory agent 55	NF-κB NO Synthase TNF Receptor Interleukin Related	Inflammation/Immunology
Anti-inflammatory agent 55 (compound 9j) is a derivative of Coixol and has anti-inflammatory activity. Anti-inflammatory agent 54 inhibits the NF-κB pathway and downregulates the expression of iNOS, TNF-α, IL-6 and IL-1β. Anti-inflammatory agent 54 inhibits LPS-induced nitric oxide (NO) production in RAW264.7 macrophages (IC₅₀: 0.8 μM) and exerts in vivo anti-inflammatory activity in a mouse auricular edema model .

HY-161996

IDO1-IN-25	Indoleamine 2,3-Dioxygenase (IDO)	Inflammation/Immunology
IDO1-IN-25 is a dual inhibitor of IDO1/TDO2, with IC₅₀ values of 0.17 μM and 3.2 μM, respectively. IDO1-IN-25 can effectively inhibit the production of NO in RAW264.7 cells stimulated by lipopolysaccharide (LPS). IDO1-IN-25 can exert anti-inflammatory effects in a mouse ear edema acute inflammation model induced by croton oil .

HY-N2535R

Coniferaldehyde (Standard)	Keap1-Nrf2 Apoptosis	Inflammation/Immunology
Coniferaldehyde (Standard) is the analytical standard of Coniferaldehyde. This product is intended for research and analytical applications. Coniferaldehyde (4-Hydroxy-3-methoxycinnamaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. Coniferaldehyde has antioxidant and anti-inflammatory activities .

Cat. No.	Product Name

HY-L161

Cytokine Inhibitors Library

891 compounds

Cytokines are a kind of low molecular soluble proteins synthesized and secreted by immunogen, mitogen or other factors. They have functions of regulating innate and adaptive immune responses, promoting hematopoiesis, stimulating cell activation, proliferation and differentiation. The process of releasing a large number of cytokines is also called “Cytokine storm”, which can cause damage to many tissues and organs in the body. Cytokine is involved in the pathogenesis of many human diseases, including cancer, diabetes, chronic inflammatory diseases and so on. Cytokine inhibitors are a class of essential compounds that act by directly inhibiting the synthesis and release of cytokine or blocking the binding of cytokine to their receptors. Cytokine inhibitors are important compounds for the study of tumor and autoimmune diseases.

MCE designs a unique collection of 891 cytokine inhibitors, mainly targeting the receptor interleukin (IL), colony-stimulating factor (CSF), interferon (IFN), tumor necrosis factor (TNF), growth factor (GF) and chemokine, which is an effective tool for development and research of anti-cancer, anti-chronic inflammatory diseases and anti-autoimmune diseases compounds.

Cat. No.	Product Name	Type

HY-159669

Stercobilin hydrochloride (mixture of isomers)

Cell Assay Reagents

Stercobilin hydrochloride (amixture of isomers) is a bile pigment metabolized by gut bacteria, and it's also an HIV protease inhibitor, with a K_i of 4 μM. Stercobilin hydrochloride (a mixture of isomers) can induce pro-inflammatory activity in mouse macrophage RAW264 cells, including the production of TNF-α and IL-1β. Stercobilin hydrochloride (a mixture of isomers) can be used in studies of inflammation and viral infections .

Cat. No.	Product Name	Target	Research Area

HY-P4717

IFN-γ Antagonist 1	IFNAR	Inflammation/Immunology
IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) is an antagonist of interferon γ (IFN γ). IFN-γ Antagonist 1 inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells with an IC₅₀ value of approximately 35 μM. IFN-γ Antagonist 1 has potential applications in immune regulation .

HY-P4717A

IFN-γ Antagonist 1 acetate	IFNAR	Inflammation/Immunology
IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate is an antagonist of interferon γ (IFN γ). IFN-γ Antagonist 1 inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells with an IC₅₀ value of approximately 35 μM. IFN-γ Antagonist 1 has potential applications in immune regulation .

HY-P10329

KK14(R)	Fungal	Infection
KK14(R) is an analog of the de novo synthetic peptide KK14, which exhibits antifungal activity against Fusarium culmorum, Penicillium expansum and Aspergillus niger , with MICs of 6.25, 12.5 and 12.5 μg/mL, respecitvely. KK14(R) exhibits good heat- and pH-stability. KK14(R) exhibits cytotoxicity against cells Caco-2 and RAW264.7 .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N3171A

(+)-Nortrachelogenin Wikstromol	Structural Classification Natural Products Classification of Application Fields Thymelaeaceae Source classification Phenols Polyphenols Plants Disease Research Fields Wikstroemia indica Cancer	Apoptosis PI3K
(+)-Nortrachelogenin (Wikstromol), a pharmacologically ligand from from wikstroemia indica, possesses antileukemic activity .

HY-N10120

Methylsyringin	Classification of Application Fields Simple Phenylpropanols Carthamus tinctorius L. Source classification Phenylpropanoids Plants Compositae Disease Research Fields Inflammation/Immunology	Others
Methylsyringin exhibits anti-inflammatory activity in the LPS-stimulated RAW264.7 cells.

HY-N2939

**Bis-5,5-Nortrachelogenin**	Structural Classification Thymelaeaceae Source classification Lignans Phenylpropanoids Plants Wikstroemia indica	Others
Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC₅₀ value of 48.6 mM .

HY-N13175

Panaxcerol B	Panax ginseng C. A. Meyer Structural Classification Source classification Plants Saccharides Araliaceae Monosaccharides	NO Synthase
Panaxcerol B is a monogalactosyl monoacylglyceride, with an IC₅₀ of 59.4 μM for NO production in LPS-stimulated RAW264.7 cells .

HY-N3548

Catalpalactone	Structural Classification Natural Products Catalpa ovata G. Don Source classification Plants Bignoniaceae	NF-κB
Catalpalactone has anti-inflammatory effect. Catalpalactone inhibits LPS-induced NO production and iNOS expression in RAW264.7 cells, and also inhibits IRF3, NF-κB, and *IFN-β/STAT-1* activation. Catalpalactone also inhibits dopamine biosynthesis by reducing tyrosine hydroxylase (TH) and aromatic-l-amino acid decarboxylase (AADC) activities .

HY-N10111

Siegesbeckialide I	Classification of Application Fields Terpenoids Pterocarpus macrocarpus Kurz Sesquiterpenes Source classification Plants Compositae Disease Research Fields Inflammation/Immunology	IKK
Siegesbeckialide I most potently inhibits LPS-induced NO production in RAW264.7 murine macrophages by directly binding to IKKα/β.

HY-N9000

Loganic acid 6′-O-β-D-glucoside	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Gentianaceae Plants Inflammation/Immunology Disease Research Fields Gentiana rhodantha Franch. ex Hemsl.	TNF Receptor
Loganic acid 6′-O-β-D-glucoside, a iridoidal glucoside, is isolated from the whole plant of Gentiana rhodantha (Gentianaceae). Loganic acid 6′-O-β-D-glucoside inhibits LPS-induced NO and TNF-α production in macrophage RAW264.7 cells .

HY-W573700

Methyl everninate	Structural Classification other families Source classification Plagiochila bifaria (Sw.) Lindenb. Phenols Plants	Others
Methyl everninate is the major constituent of the deuterochloroform. Methyl everninate, rhodomollosides A and B are the derivatives of Methyl everninate, with cytotoxicity against RAW264.7 cells. Both of they shows inhibitory effects with a lipopolysaccharide (LPS)-stimulated murine macrophages RAW 264.7 cells model .

HY-N2989

3-O-Acetyl-16α-hydroxydehydrotrametenolic acid	Other Terpenoids Classification of Application Fields Terpenoids Source classification Polyporaceae Poria cocos Plants Disease Research Fields Inflammation/Immunology	NO Synthase
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid, an anti-inflammatory triterpenoid, inhibits NO production and iNOS expression in LPS-stimulated Raw264.7 cells .

HY-N11544

Inflexuside B	Structural Classification Natural Products Labiatae Source classification Artemisia tanacetifolia L. Plants	NO Synthase
Inflexuside B, an abietane diterpenoid, can be isolated from the aerial parts of Isodon inflexus. Inflexuside B strongly inhibits lipopolysaccharide (LPS)-activated NO Synthase in RAW264.7 macrophages .

HY-N11548

Inflexuside A	Structural Classification Terpenoids Labiatae Source classification Artemisia tanacetifolia L. Diterpenoids Plants	NO Synthase
Inflexuside A, an abietane diterpenoid, can be isolated from the aerial parts of Isodon inflexus. Inflexuside B strongly inhibits lipopolysaccharide (LPS)-activated NO production (NO Synthase) in RAW264.7 macrophages .

HY-N1912

Andropanolide	Structural Classification Natural Products Andrographis paniculata (Burm. F.) Nees Acanthaceae Classification of Application Fields Source classification Plants Inflammation/Immunology Disease Research Fields	Others
Andropanolide is a natural product that exerts cytotoxicity toward carcinoma cells and significantly inhibits the overproduction of nitric oxide (NO) in Lipopolysaccharides (HY-D1056) (LPS)-stimulated RAW264.7 macrophages .

HY-N12283

NF-κB-IN-13	Structural Classification Natural Products Thymelaeaceae Source classification Plants Aquilaria sinensis (Lour.) Spreng.	NF-κB
NF-κB-IN-13 (compound 12) can significantly inhibit LPS-induced NF-κB activation and NO production in RAW264.7 macrophages. NF-κB-IN-13 has anti-inflammatory effects .

HY-N13184

Giraldoid B	Structural Classification Thymelaeaceae Source classification Daphne giraldii Nitsche Coumarins Phenylpropanoids Plants	TNF Receptor
Giraldoid B is an active ingredient that can be isolated from Girald Daphne Bark. Giraldoid B can inhibit LPS induced NO and b>TNF-α production in RAW264.7 and has anti-inflammatory activity .

HY-N13138

Angulasaponin B	Triterpenes Structural Classification Leguminosae Terpenoids Source classification Vigna angularis (Willd.) Ohwi et Ohashi Plants	NO Synthase
Angulasaponin B, a natural product, can be obtained from Vigna angularis. Angulasaponin B inhibits nitric oxide production in LPS-activated RAW264.7 macrophages with IC₅₀ values ranging from 13 μM to 24 μM .

HY-N12494

Diplacol	Structural Classification other families Source classification Paulownia coreana UYEKI Phenols Polyphenols Plants	NO Synthase
Diplacol is a geranylated flavanone that can be isolated from paulownia trees (Paulownia coreana UYEKI). Diplacol has anti-inflammatory activity. Diplacol inhibits NO production in LPS-stimulated Raw264.7 cells with an IC₅₀ value of 4.53 μM .

HY-N3171

*Nortrachelogenin* (-)-Wikstromol; (-)-Nortrachelogenin	Structural Classification Natural Products other families Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	Apoptosis
Nortrachelogenin ((-)-Wikstromol) from Partrinia scabiosaefolia elicits an apoptotic response in Candida albicans .

HY-N12042

Taxamairin B	Structural Classification Terpenoids Source classification Taxaceae Diterpenoids Plants Taxus wallichiana var. mairei (Lemee & H. Léveillé) L. K. Fu & Nan Li	TNF Receptor PI3K Reactive Oxygen Species Interleukin Related
Taxamairin B is a potent anti-inflammatory agent. Taxamairin B decreases proinflammatory cytokines (TNF-α, IL-1β and IL-6) expression and the production of NO and ROS in LPS-induced RAW264.7 cells. Taxamairin B exhibits significant protective effects in LPS-induced acute lung injury in mice .

HY-N8805

Nortrachelogenin-8'-O-β-glucoside	Ranunculaceae Phenols Polyphenols Plants Pulsatilla cernua (Thunb.) Bercht. et Opiz.	Others
Nortrachelogenin-8'-O-β-glucoside is a natural product that can be isolated from the dried roots of Pulsatilla koreana. Nortrachelogenin-8'-O-β-glucoside inhibits cancer cell proliferation and reduces hormone dependence .

HY-N11657

Sanggenon A Sanggenone A	Structural Classification Flavonoids Source classification Morus alba L. Plants Moraceae Other Flavonoids	NF-κB Keap1-Nrf2
Sanggenon A (Sanggenone A) exerts anti-inflammatory effects by regulating NF-κB and HO-1/Nrf2 signaling pathways in BV2 and RAW264.7 cells. Sanggenon A markedly inhibits the Lipopolysaccharide (LPS; HY-D1056)-induced production of nitric oxide .

HY-N0634

Cimifugin 1 Publications Verification Cimitin	Structural Classification Classification of Application Fields Ranunculaceae Coumarins Phenylpropanoids Plants Cimicifuga racemosa (L.) Nutt. Inflammation/Immunology Disease Research Fields	NF-κB
Cimifugin (Cimitin) is a bioactive component of Cimicifuga racemosa, a Chinese herb. Cimifugin suppresses allergic inflammation by reducing epithelial derived initiative key factors via regulating tight junctions . Cimifugin reduces the migration and chemotaxis of RAW264.7 cells and inhibits the release of inflammatory factors and activation of MAPKs and NF-κB signaling pathways induced by LPS .

HY-N12235

Sarglaroids F	Structural Classification Ketones, Aldehydes, Acids Source classification Sarcandra glabra (Thunb.) Nakai Chloranthaceae Plants	Caspase
Sarglaroids F (compound 6) is an anti-inflammatory agent isolated from the roots of Grass Coral. Sarglaroids F inhibits LPS/ATP-induced IL-1β release by affecting K+ efflux and reducing Caspase-1(P20) levels. Sarglaroids F is not cytotoxic to RAW264.7 cells .

HY-N2838

Alismol	Structural Classification Animals Terpenoids Sesquiterpenes Source classification	NO Synthase
Alismol is a natural sesquiterpene. Alismol shows promising inhibitory effects on INF-γ-induced nitric oxide production in murine macrophage RAW264.7 cells .

HY-N10062

Amakusamine	Alkaloids Structural Classification other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields Indole Alkaloids	RANKL/RANK
Amakusamine inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced formation of multinuclear osteoclasts with an IC₅₀ value of 10.5 μM in RAW264.7 cells.

HY-130787

Apterin	Structural Classification Carpesium divaricatum Siebold & Zucc. Source classification Plants Umbelliferae Saccharides Monosaccharides	NO Synthase
Apterin is a natural compound with anti-inflammatory activity. Apterin shows significantly inhibitory activity on NO production in RAW264.7 cells with an IC₅₀ value of 41.8 μM .

HY-N13160

Sanggenon F	Structural Classification Flavonoids Flavonones Source classification Plants Moraceae Morus alba Linn.	Others
Sanggenon F is a flavonoid compound derived from Morus alba var. multicaulis. It inhibits the differentiation of 3T3-L1 adipocytes and the production of nitric oxide (NO) in RAW264.7 cells induced by lipopolysaccharides (HY-D1056) and IFN-γ (IC₅₀ of 19 nM). Sanggenon F has potential application value in the fields of anti-inflammatory and metabolic diseases .

HY-N2535

Coniferaldehyde 1 Publications Verification 4-Hydroxy-3-methoxycinnamaldehyde	Structural Classification Monophenols other families Classification of Application Fields Simple Phenylpropanols Source classification Phenols Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Keap1-Nrf2 Apoptosis
Coniferaldehyde (4-Hydroxy-3-methoxycinnamaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. Coniferaldehyde has antioxidant and anti-inflammatory activities .

HY-N1695

Demethylregelin Regelin acid	Structural Classification Terpenoids Source classification Celastraceae Plants Pentacyclic Triterpenoids Euonymus alatus (Thunb.) Sieb.	NO Synthase
Demethylregelin (Regelin acid), a triterpene, effectively reduces the expression of iNOS protein and subsequent nitric oxide production induced by lipopolysaccharide (HY-D1056) in RAW264.7 cells. Demethylregelin has anti-inflammatory activities .

HY-N11990

Nortrachelogenin 4'-O-β-gentiobioside	Apocynaceae Structural Classification Monophenols Source classification Lignans Phenols Phenylpropanoids Plants Trachelospermum jasminoides (Lindl.) Lem.	Others
Nortrachelogenin 4'-O-β-gentiobioside (compound 20) is a lignan isolated from the aerial parts of Trachelospermius .

HY-N0634R

Cimifugin (Standard)	Structural Classification Ranunculaceae Coumarins Phenylpropanoids Plants Cimicifuga racemosa (L.) Nutt.	NF-κB
Cimifugin (Standard) is the analytical standard of Cimifugin. This product is intended for research and analytical applications. Cimifugin (Cimitin) is a bioactive component of Cimicifuga racemosa, a Chinese herb. Cimifugin suppresses allergic inflammation by reducing epithelial derived initiative key factors via regulating tight junctions . Cimifugin reduces the migration and chemotaxis of RAW264.7 cells and inhibits the release of inflammatory factors and activation of MAPKs and NF-κB signaling pathways induced by LPS .

HY-N3392

Lethedoside A	Structural Classification Flavonoids Flavones Thymelaeaceae Source classification Plants Aquilaria sinensis (Lour.) Spreng.	NO Synthase
Lethedoside A is a natural flavonoid that shows inhibitory activity for LPS-induced NO production in RAW 264.7 cells .

HY-N11988

Nortrachelogenin 5'-C-β-glucopyranoside	Apocynaceae Structural Classification Source classification Lignans Phenols Polyphenols Phenylpropanoids Plants Trachelospermum jasminoides (Lindl.) Lem.	Others
Nortrachelogenin 5'-C-β-glucopyranoside (compound 3) is a glycoside compound that can be isolated from the aerial parts of Trachelospermia vine .

HY-N2620

Rutaevin	Other Terpenoids Classification of Application Fields Terpenoids Source classification Evodia rutaecarpa (Juss.) Benth. Rutaceae Plants Disease Research Fields Inflammation/Immunology	Reactive Oxygen Species
Rutaevin is isolated from the fruits of Euodia rutaecarpa. Rutaevin inhibits NO production in LPS-induced RAW 264.7 macrophages .

HY-N9337

Amaroswerin	Iridoids Classification of Application Fields Terpenoids Source classification Gentianaceae Phenols Polyphenols Metabolic Disease Swertia mussotii Franch. Plants Disease Research Fields Inflammation/Immunology	NO Synthase
Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC₅₀ value of 5.42 μg/mL in RAW264.7 cells .

HY-N2535R

Coniferaldehyde (Standard)	Structural Classification Monophenols other families Simple Phenylpropanols Source classification Phenols Phenylpropanoids Plants	Keap1-Nrf2 Apoptosis
Coniferaldehyde (Standard) is the analytical standard of Coniferaldehyde. This product is intended for research and analytical applications. Coniferaldehyde (4-Hydroxy-3-methoxycinnamaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. Coniferaldehyde has antioxidant and anti-inflammatory activities .

HY-N10114

Hyperectumine	Alkaloids Classification of Application Fields Source classification Hypecoum erectum L. Plants Isoquinoline Alkaloids Disease Research Fields Inflammation/Immunology Papaveraceae	Others
Hyperectumine exhibits moderate anti-inflammatory activity via suppression of LPS-activated inflammatory mediators in RAW 264.7 macrophage cells.

HY-N3383

Ligustroside Ligstroside	Monophenols Iridoids Oleaceae Ligustrum japonicum Thunb. Terpenoids Source classification Phenols Plants	Mitochondrial Metabolism
Ligustroside (Ligstroside), a secoiridoid derivative, has outstanding performance on mitochondrial bioenergetics in models of early Alzheimer's disease (AD) and brain ageing by mechanisms that may not interfere with Aβ production. Ligustroside significantly inhibits nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophages .

HY-N0997

*(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one*	Structural Classification Classification of Application Fields Source classification Phenols Curcuma kwangsiensis S. K. Lee & C. F. Liang Plants Inflammation/Immunology Disease Research Fields Cancer Zingiberaceae	NO Synthase
(6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one (compound7) is a nature product isolated from rhizomes of Curcuma kwangsiensis. (6E)-1,7-Bis(4-hydroxyphenyl)-6-hepten-3-one has inhibitory effect on NO production induced by LPS in macrophages with an IC₅₀ value of 8.93 μM .

HY-N6257

Cafestol 1 Publications Verification	Structural Classification Classification of Application Fields Terpenoids Rubiaceae Diterpenoids Plants Inflammation/Immunology Disease Research Fields Cancer	ERK PGE synthase COX NF-κB
Cafestol, one of the major components of coffee, is a coffee-specific diterpene from. Cafestol is a ERK inhibitor for AP-1-targeted activity against PGE₂ production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE₂ production by suppressing the NF-kB activation pathway. Cafestol contributes to its beneficial effects through various biological activities such as chemopreventive, antitumorigenic, hepatoprotective, antioxidative and antiinflammatory effects .

HY-N9896

Anhydronotoptol	Structural Classification Natural Products Source classification Plants Umbelliferae Kleinia odora (Forssk.) DC.	NO Synthase
Anhydronotoptol is a potent nitric oxide inhibitory coumarin. Anhydronotoptol inhibits NO production in RAW 264.7 cells induced by LPS with an IC₅₀ value of 36.6 μM .

HY-N10297

Curindolizine	Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Inflammation/Immunology	Others
Curindolizine, indolizine alkaloid , displays an anti-inflammatory action in lipopolyssacharide (LPS)-induced RAW 264.7 macrophages with an IC₅₀ value of 5.31 μM .

HY-N6257R

Cafestol (Standard)	Structural Classification Terpenoids Rubiaceae Diterpenoids Plants	ERK PGE synthase COX NF-κB
Cafestol (Standard) is the analytical standard of Cafestol. This product is intended for research and analytical applications. Cafestol, one of the major components of coffee, is a coffee-specific diterpene from. Cafestol is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway. Cafestol contributes to its beneficial effects through various biological activities such as chemopreventive, antitumorigenic, hepatoprotective, antioxidative and antiinflammatory effects .

HY-N8910

(7R)-Methoxy-8-epi-matairesinol	Structural Classification Thymelaeaceae Source classification Lignans Phenylpropanoids Plants Wikstroemia indica	Others
(7R)-Methoxy-8-epi-matairesinol is a Lignans product that can be isolated from the roots of Wikstroemia indica .

HY-N10865

Chloranthalactone E	Structural Classification Terpenoids Sesquiterpenes Source classification Chloranthaceae Plants	NO Synthase
Chloranthalactone E (compound 6), a labdane diterpene, can be isolated from the aerial parts of Chloranthus serratus. Chloranthalactone E inhibits NO production in LPS-activated RAW 264.7 macrophages .

HY-N1080

Vitexdoin A	Structural Classification Verbenaceae Source classification Lignans Phenylpropanoids Plants Vitex negundo Linn.	Others
Vitexdoin A is a nitric oxide scavenging lignin. Vitexdoin A inhibits NO production with an IC₅₀ of 0.38 μM in LPS (HY-D1056)-stimulated RAW 264.7 cells .

HY-N9891

12-Dehydrogingerdione 12-DHGD	Zingiber officinale Roscoe Structural Classification Monophenols Source classification Phenols Plants Zingiberaceae	NO Synthase Interleukin Related
12-Dehydrogingerdione is an inhibitor of NO Synthase. 12-Dehydrogingerdione signi?cantly inhibits LPS-stimulated production of NO, IL-6 and PGE2 in Raw 264.7 cells .

HY-N3289A

(E)-Methyl 3,4,5-trimethoxycinnamate	Simple Phenylpropanols Piper tuberculatum jacq. Source classification Piperaceae Phenylpropanoids Plants	Others
(E)-Methyl 3,4,5-trimethoxycinnamate is a bioactive natural phenylpropanoid. (E)-Methyl 3,4,5-trimethoxycinnamate suppresses inflammation in RAW264.7 macrophages and blocks macrophage-adipocyte interaction. (E)-Methyl 3,4,5-trimethoxycinnamate also has antiarrhythmic effect, leads to suppression of triggered activities in rabbit myocytes .

HY-N11570

Phaeocaulisin E	Structural Classification Terpenoids Sesquiterpenes Source classification Plants Curcuma phaeocaulis Valeton Zingiberaceae	Others
Phaeocaulisin E (Compound 5) is a guaiane-type sesquiterpene that inhibits LPS HY-(HY-D1056)-induced NO production in RAW 264.7 macrophages with an IC₅₀ of 10.3 μM .

HY-N10156

1,3,5-Trihydroxy-4-prenylxanthone	Flavonoids Leguminosae Source classification Plants Other Flavonoids Erythrina variegata Linn.	Na+/H+ Exchanger (NHE) Phosphodiesterase (PDE) NO Synthase
1,3,5-Trihydroxy-4-prenylxanthone is a Na ⁺/H ⁺ exchange system (Na+/H+ Exchanger (NHE)) inhibitor with a minimum inhibitory concentration of 10 μg/mL . 1,3,5-Trihydroxy-4-prenylxanthone is a phosphodiesterase type 5 (PDE5) (Phosphodiesterase (PDE)) inhibitor with an IC₅₀ value of 3.0 μM . 1,3,5-Trihydroxy-4-prenylxanthone inhibits Lipopolysaccharide (LPS) (Lipopolysaccharides (HY-D1056))-induced NO production in RAW264.7 macrophages, and has anti-inflammatory activities .

HY-N2794

9-Hydroxy-α-lapachone α-Dihydrocaryopterone	Quinones Structural Classification Catalpa ovata G. Don Monophenols Source classification Phenols Plants Bignoniaceae Naphthalene Quinones	NO Synthase
9-Hydroxy-α-lapachone (α-Dihydrocaryopterone) is a natural phenol, exhibits potent inhibitory effects with an IC₅₀ of 4.64 µM on LPS-induced NO production in RAW 264.7 cells .

Species:	Human (45) Rhesus Macaque (4) Mouse (27) Rat (7) Bovine (1) Cynomolgus (8) Sheep (1) Canine (1) Pig (2)
Tag:	His (50) SUMO (1) Tag Free (25) Avi (5) Myc (1) Fc (21) Flag (1)
Source:	HEK293 (59) CHO (3) P. pastoris (10) E. coli (26)

Cat. No.	Compare	Product Name	Species	Source

HY-P79295

	IFN-gamma Protein, Canine Interferon gamma; IFN-gamma; IFNG	Canine	E. coli
	IFN-gamma (interferon-gamma) is a type II interferon produced by immune cells such as T cells and NK cells, and plays a key role in activating antibacterial, antiviral, and antitumor responses. Through the JAK-STAT pathway, its interaction with the receptor IFNGR1 triggers gene regulation. IFN-gamma Protein, Canine is the recombinant canine-derived IFN-gamma protein, expressed by E. coli , with tag free. The total length of IFN-gamma Protein, Canine is 143 a.a., with molecular weight of ~16.25 kDa.

HY-P79429

	IFN-gamma Protein, Pig Interferon gamma; IFNG; IFN-gamma	Pig	E. coli
	IFN-gamma (interferon-gamma) is a type II interferon produced by immune cells such as T cells and NK cells. It plays a key role in antibacterial, antiviral and anti-tumor responses by activating effector immune cells and enhancing antigen presentation. effect. Its main signaling pathway involves the JAK-STAT pathway that interacts with its receptor IFNGR1, affecting gene regulation. IFN-gamma Protein, Pig is the recombinant Pig-derived IFN-gamma protein, expressed by E. coli , with tag free.

HY-P72245

	IFN-gamma Protein, Sheep (His) IFNG; Interferon gamma; IFN-gamma	Sheep	E. coli
	IFN-gamma (interferon-gamma) is a type II interferon produced by T cells and NK cells, which can significantly activate antibacterial, antiviral and antitumor responses. It acts through the JAK-STAT pathway and its receptor IFNGR1 to affect gene regulation. IFN-gamma Protein, Sheep (His) is the recombinant sheep-derived IFN-gamma protein, expressed by E. coli , with N-6*His labeled tag. The total length of IFN-gamma Protein, Sheep (His) is 143 a.a., with molecular weight of ~21 kDa.

HY-P7071

	IFN-gamma Protein, Mouse 10+ Cited Publications rMuIFN-γ; IFNG; IFN-gamma; Interferon gamma	Mouse	E. coli
	IFN-gamma Protein, Mouse is a pro-inflammatory cytokine with potent immunomodulatory, anti-proliferative, and antiviral properties.

HY-P7095

	IFN-gamma Protein, Rat 2 Publications Verification rRtIFN-γ; IFNG; IFN-gamma; Interferon gamma	Rat	E. coli
	IFN-gamma Protein, Rat is a pro-inflammatory cytokine with potent immunomodulatory, anti-proliferative, and antiviral properties.

HY-P7025

	IFN-gamma Protein, Human Maximum Cited Publications 30 Publications Verification rHuIFN-γ; IFNG; IFN-gamma; Interferon gamma	Human	E. coli
	IFN-gamma Protein, Human is a cytokine with potent immunomodulatory, antiviral and antitumor activities.

HY-P70667

	IFN-gamma Protein, Mouse (HEK293) IFNg; Interferon gamma; IFN-gamma	Mouse	HEK293
	IFN-gamma is a type II interferon family cytokine that participates in antiviral, antibacterial, and antitumor responses. IFN-gamma Protein, Mouse (HEK293) is the recombinant mouse-derived IFN-gamma protein, expressed by HEK293 , with tag free.

HY-P7095A

	IFN-gamma Protein, Rat (CHO) rRtIFN-γ; IFNG; IFN-gamma; Interferon gamma	Rat	CHO
	IFN-gamma Protein, Rat (CHO) is a pro-inflammatory cytokine with potent immunomodulatory, anti-proliferative, and antiviral properties.

HY-P74863

	IFN-alpha B/IFNA8 Protein, Cynomolgus (HEK293, His) IFNA8; IFN-alpha 8; IFN-alpha B2; IFN-alpha-8; LeIF B	Cynomolgus	HEK293
	IFN-alpha B/IFNA8 protein is a member of the alpha/beta interferon family. IFN-alpha B/IFNA8 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IFN-alpha B/IFNA8 protein, expressed by HEK293, with C-His labeled tag. The total length of IFN-alpha B/IFNA8 Protein, Cynomolgus (HEK293, His) is 166 a.a., with molecular weight of ~33 kDa.

HY-P72516

	IFN-zeta/Limitin Protein, Mouse (HEK293, His) Limitin; IFN-z; BGIF; IFNz; interferon zeta; Lmtn; IFN-zeta	Mouse	HEK293
	IFN-zeta/Limitin protein is a member of the alpha/beta interferon family. IFN-zeta/Limitin Protein, Mouse (HEK293, His) is the recombinant mouse-derived IFN-zeta/Limitin protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IFN-zeta/Limitin Protein, Mouse (HEK293, His) is 161 a.a., with molecular weight of ~19 kDa.

HY-P7025A

	IFN-gamma Protein, Human (CHO) 1 Publications Verification rHuIFN-γ; IFNG; IFN-gamma; Interferon gamma	Human	CHO
	IFN-gamma Protein, Human (CHO) is a cytokine with potent immunomodulatory, antiviral and antitumor activities.

HY-P70668

	IFN-gamma Protein, Mouse (HEK293, His) IFNg; Interferon gamma; IFN-gamma	Mouse	HEK293
	IFN-gamma is a type II interferon family cytokine that participates in antiviral, antibacterial, and antitumor responses. IFN-gamma Protein, Mouse (HEK293, His) is the recombinant mouse-derived IFN-gamma protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IFN-gamma Protein, Mouse (HEK293, His) is 133 a.a., with molecular weight of 15-28 kDa.

HY-P78552

	*GMP IFN-gamma Protein, Human* Interferon Gamma; IFN-Gamma; Immune Interferon; IFNG	Human	E. coli
	IFN-gamma Protein is a dimeric soluble cytokine. It exerts antibacterial, antiviral and antitumor effects through JAK-STAT, mTOR, MAPK and PI3K/AKT signaling pathways. GMP IFN-gamma Protein, Human is the recombinant human-derived IFN-gamma protein, expressed by E. coli , with tag free. The total length of GMP IFN-gamma Protein, Human is 143 a.a., with molecular weight of ~16.7 kDa.

HY-P700091AF

	*Animal-Free IFN-gamma Protein, Human (His)* IFNG; IFN-gamma; Interferon gamma	Human	E. coli
	IFN-gamma Protein is a dimeric soluble cytokine. It exerts antibacterial, antiviral and antitumor effects through JAK-STAT, mTOR, MAPK and PI3K/AKT signaling pathways. Animal-Free IFN-gamma Protein, Human (His) is the recombinant human-derived animal-FreeIFN-gamma protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IFN-gamma Protein, Human (His) is 143 a.a., with molecular weight of ~17.7 kDa.

HY-P77391

	IFN-alpha 4 Protein, Cynomolgus (HEK293, Fc) Interferon alpha-4; IFN-alpha-4; INFA4	Cynomolgus	HEK293
	IFN-alpha 4 (IFNA4), belongs to type I interferon family, is produced by macrophages with antiviral activities. IFN-alpha 4 Protein, Cynomolgus (HEK293, Fc) contains 189 a.a. (M1-N189), produced in HEK293 cells with a C-terminal mFc-tag.

HY-P78308

	IFNAR1 Protein, Mouse (HEK293, Fc) AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC ; IFN-alpha/β R1	Mouse	HEK293
	IFNAR1, one of the subunit of IFN-α/β receptor, is a type I IFN receptor. IFNAR1 forms the heterodimeric receptor with IFNAR2. IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2). Upon activation by these IFNs, IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2. IFNAR1 Protein, Mouse (HEK293, Fc) is a recombinant mouse IFNAR1 (E27-T429) with C-terminal hFc tag, which is produced in HEK293 cells.

HY-P73861

	IFN-alpha B/IFNA8 Protein, Human (HEK293) IFNA8; IFN-alpha 8; IFN-alpha B2; Interferon alpha-8; Interferon alpha-B	Human	HEK293
	IFN-alpha B/IFNA8 Protein, synthesized by macrophages, displays potent antiviral activities. It stimulates the production of essential enzymes—a protein kinase and an oligoadenylate synthetase—that are pivotal in cellular defense against viral infections. IFN-alpha B/IFNA8 Protein, Human (HEK293) is the recombinant human-derived IFN-alpha B/IFNA8 protein, expressed by HEK293 , with tag free.

HY-P78309

	IFNAR1 Protein, Mouse (HEK293, His-Avi) AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC ; IFN-alpha/β R1	Mouse	HEK293
	IFNAR1, one of the subunit of IFN-α/β receptor, is a type I IFN receptor. IFNAR1 forms the heterodimeric receptor with IFNAR2. IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2). Upon activation by these IFNs, IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2. IFNAR1 Protein, Mouse (HEK293, Fc) is a recombinant mouse IFNAR1 (E27-T429) with C-terminal His and Avi tags, which is produced in HEK293 cells.

HY-P78457

	IFNAR1 Protein, Human (HEK293, His-Avi) AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC ; IFN-alpha/β R1	Human	HEK293
	IFNAR1, one of the subunit of IFN-α/β receptor, is a type I IFN receptor. IFNAR1 forms the heterodimeric receptor with IFNAR2. IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2). Upon activation by these IFNs, IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2. IFNAR1 Protein, Human (HEK293, His-Avi) is a recombinant human IFNAR1 (K28-K436) with C-terminal His and Avi tag, which is produced in HEK293 cells.

HY-P70610

	IFN-gamma Protein, Human (HEK293) 1 Publications Verification Interferon Gamma; IFN-Gamma; Immune Interferon; IFNG	Human	HEK293
	IFN-gamma Protein is a dimeric soluble cytokine. It exerts antibacterial, antiviral and antitumor effects through JAK-STAT, mTOR, MAPK and PI3K/AKT signaling pathways. IFN-gamma Protein, Human (HEK293) is the recombinant human-derived IFN-gamma protein, expressed by HEK293 , with tag free. The total length of IFN-gamma Protein, Human (HEK293) is 143 a.a., with molecular weight of 20-25 & 16-17 kDa, respectively.

HY-P73128

	IFN-beta Protein, Human (CHO) Interferon beta; IFN-beta; IFNB1; IFB; IFNB	Human	CHO
	IFN-β (interferon-β) is a key type I interferon cytokine that coordinates the innate immune response to infection, tumors, and inflammation. IFN-β binds to high-affinity (IFNAR2) and low-affinity (IFNAR1) heterodimeric receptors, activates Jak-STAT signaling, and modulates interferon-regulated genes. IFN-beta Protein, Human (CHO) is the recombinant human-derived IFN-beta protein, expressed by CHO , with tag free.

HY-P73860

	IFN-alpha B/IFNA8 Protein, Human (HEK293, His) IFNA8; IFN-alpha 8; IFN-alpha B2; Interferon alpha-8; Interferon alpha-B	Human	HEK293
	IFN-alpha B/IFNA8 Protein, synthesized by macrophages, displays potent antiviral activities. It stimulates the production of essential enzymes—a protein kinase and an oligoadenylate synthetase—that are pivotal in cellular defense against viral infections. IFN-alpha B/IFNA8 Protein, Human (HEK293, His) is the recombinant human-derived IFN-alpha B/IFNA8 protein, expressed by HEK293 , with C-His labeled tag.

HY-P78141

	IFNAR1 Protein, Human (Biotinylated, HEK293, His-Avi) AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC ; IFN-alpha/β R1	Human	HEK293
	IFNAR1, one of the subunit of IFN-α/β receptor, is a type I IFN receptor. IFNAR1 forms the heterodimeric receptor with IFNAR2. IFNAR1 mediates IFN-induced STAT signaling by interacting with tyrosine kinase 2 (Tyk2). Upon activation by these IFNs, IFNAR1 and IFNAR2 undergo a conformational change to promote a cascade of downstream signaling events, including the phosphorylation of Tyk2 and JAK1, STAT1 and STAT2. IFNAR1 Protein, Human (Biotinylated, HEK293, His-Avi) is a biotinylated recombinant human IFNAR1 (K28-K436) with C-terminal His and Avi tag, which is produced in HEK293 cells.

HY-P74866

	IFN-alpha 1/IFNA1 Protein, Mouse (P.pastoris, His) IFNA1; IFNalpha 1; IFN-alpha 1	Mouse	P. pastoris
	IFN-alpha 1 (IFNA1), belongs to type I interferon family, is produced by macrophages with antiviral activities. IFN-alpha 1 involves in the activation of JAK1 and TYK2 pathway, exerts function by inhibiting viral replication as well as modulating immune response. IFN-alpha 1/IFNA1 Protein, Mouse (P.pastoris, His) is produced in P.pastoris yeast cells with a C-Terminal His-tag.

HY-P70610G

	*GMP IFN-gamma Protein, Human (HEK293)* Interferon Gamma; IFN-Gamma; Immune Interferon; IFNG	Human	HEK293
	IFN-gamma Protein is a dimeric soluble cytokine. It exerts antibacterial, antiviral and antitumor effects through JAK-STAT, mTOR, MAPK and PI3K/AKT signaling pathways. GMP IFN-gamma Protein, Human (HEK293) is the recombinant human-derived IFN-gamma protein, expressed by HEK293 , with tag free. The total length of GMP IFN-gamma Protein, Human (HEK293) is 143 a.a., with molecular weight of 16 & 18 & 25 kDa, respectively.

HY-P73130

	IFN-beta Protein, Mouse (HEK293) 1 Publications Verification Interferon beta; IFN-beta; IFNB1; IFB; IFNB	Mouse	HEK293
	IFN-β protein is a type I interferon that plays a key role in the innate immune response by binding to IFNAR2 and IFNAR1 receptors and activating Jak-STAT signaling. This results in transcriptional regulation of interferon-regulated genes, affecting antiviral proteins, cell proliferation regulators, and immunomodulatory proteins. IFN-beta Protein, Mouse (HEK293) is the recombinant mouse-derived IFN-beta protein, expressed by HEK293 , with tag free.

HY-P700184AF

	*Animal-Free IFN-gamma Protein, Mouse (His)* rMuIFN-γ; IFNG; IFN-gamma; Interferon gamma	Mouse	E. coli
	IFN-gamma is a type II interferon family cytokine that participates in antiviral, antibacterial, and antitumor responses. Animal-Free IFN-gamma Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIFN-gamma protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IFN-gamma Protein, Mouse (His) is 133 a.a., with molecular weight of ~16.5 kDa.

HY-P78672

	IFN-alpha 2b/IFNA2 Protein, Human (HEK293, Fc) IFN-alpha 2b; IFNA2B; IFN-alpha 2 (alpha 2b); interferon alpha 2b	Human	HEK293
	IFN-alpha 2a, Human, a cytokine primarily produced by macrophages, displays robust antiviral activities. Its interaction with IFNAR2 is pivotal in mediating essential signaling pathways, contributing to intricate defense mechanisms against viral infections. IFN-alpha 2b/IFNA2 Protein, Human (HEK293, Fc) is the recombinant human-derived IFN-alpha 2b/IFNA2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IFN-alpha 2b/IFNA2 Protein, Human (HEK293, Fc) is 165 a.a., with molecular weight of 45-55 kDa.

HY-P701006

	IFN-gamma Protein, Cynomolgus (HEK293, His) IFN-gamma-R1; CDw119; CD119; IFNGR1; IFNGR; AVP; FLJ45734; IFN-gamma R1; IFN-gR1; type 2	Cynomolgus	HEK293
	IFN-gamma (interferon-gamma) is a type II interferon derived from immune cells such as T cells and NK cells, which can significantly activate effector immune cells and enhance antigen presentation. It affects gene regulation through the JAK-STAT pathway and its receptor IFNGR1. IFN-gamma Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IFN-gamma protein, expressed by HEK293 , with C-His labeled tag. The total length of IFN-gamma Protein, Cynomolgus (HEK293, His) is 142 a.a., with molecular weight of 25-35 kDa.

HY-P701060

	IFNAR2 Protein, Cynomolgus (HEK293, His) IFN-R-2; IFNAR2; IFNARB; IFNABR; IFN-alpha; IFN-alpha/beta R2; IFNbR2; IFN-R; β receptor 2; β receptor10;	Cynomolgus	HEK293

HY-P73202

	IFN-lambda 1/IL-29 Protein, Human (HEK293) IFN-λ1/IL-29; IL-29; IFN-lambda-1; Cytokine Zcyto21; Interleukin-29	Human	HEK293
	IFN-lambda 1 (IL-29) is a member of the Type-III interferon family. IFN-lambda 1 signals through a heterodimeric receptor complex comprising IFNλ receptor 1 (IFNLR1) and IL-10 receptor subunit-β (IL-10RB). When IFN-lambda 1 binds with the receptor complex, Jak1 and Tyk2 will be activated, and leads to subsequent tyrosine phosphorylation of the IFN-λR1, and activation of STAT1 and STAT2. IFN-lambda 1 modulates immunity in infections and autoimmune diseases. IFN-lambda 1/IL-29 Protein, Human (HEK293) is a recombinant human IFN-lambda 1 (G20-T200) without any tag, which is produced in HEK293 cell.

HY-P78772

	IFN-alpha/beta R2 Protein, Mouse (HEK293, His) IFNAR2; IFNARB; IFNABR; IFN-R-2; IFN-alpha; beta receptor 2	Mouse	HEK293
	IFN-α/β R2 protein and IFNAR1 together constitute the heterodimeric receptor of type I interferon and initiate the JAK-STAT signaling cascade. Upon binding of type I interferons, IFNAR1 and IFNAR2 activate related Janus kinases (TYK2 and JAK1) in proximity, resulting in cross-phosphorylation. IFN-alpha/beta R2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IFN-alpha/beta R2 protein, expressed by HEK293 , with C-His, C-6*His labeled tag. The total length of IFN-alpha/beta R2 Protein, Mouse (HEK293, His) is 221 a.a., with molecular weight of ~37-57 kDa.

HY-P73129

	IFN-beta Protein, Human (HEK293, Fc) 1 Publications Verification Interferon beta; IFN-beta; IFNB1; IFB; IFNB	Human	HEK293
	IFN-β (interferon-β) is a key type I interferon cytokine that coordinates the innate immune response to infection, tumors, and inflammation. IFN-β binds to high-affinity (IFNAR2) and low-affinity (IFNAR1) heterodimeric receptors, activates Jak-STAT signaling, and modulates interferon-regulated genes. IFN-beta Protein, Human (HEK293, Fc) is the recombinant human-derived IFN-beta protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P73131

	IFN-beta Protein, Mouse (HEK293, Fc) Interferon beta; IFN-beta; IFNB1; IFB; IFNB	Mouse	HEK293
	IFN-β protein is a type I interferon that plays a key role in the innate immune response by binding to IFNAR2 and IFNAR1 receptors and activating Jak-STAT signaling. This results in transcriptional regulation of interferon-regulated genes, affecting antiviral proteins, cell proliferation regulators, and immunomodulatory proteins. IFN-beta Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IFN-beta protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IFN-beta Protein, Mouse (HEK293, Fc) is 182 a.a., with molecular weight of ~58 kDa.

HY-P73132

	IFN-beta Protein, Rhesus (HEK293, Fc) Interferon beta; IFN-beta; IFNB1; IFB; IFNB	Rhesus Macaque	HEK293
	IFN-beta Protein is an immunomodulatory cytokine of the type 1 interferon family. IFN-beta Protein reduces joint inflammation by inhibiting the RANKL-c-Fos signaling pathway. IFN-beta Protein regulates mitochondrial fission through STAT5, PGAM5, and Drp1 to rescue neurodegeneration. IFN-beta Protein, Rhesus (HEK293, Fc) is the recombinant Rhesus Macaque-derived IFN-beta protein, expressed by HEK293 , with C-mFc labeled tag. The total length of IFN-beta Protein, Rhesus (HEK293, Fc) is 166 a.a., with molecular weight of ~46.4 kDa.

HY-P73252

	IFN-gamma Protein, Mouse (HEK293, Fc) IFG; IFI; IFNG; IFN-gamma; Immune interferon; Interferon gamma	Mouse	HEK293
	IFN-gamma is a type II interferon family cytokine that participates in antiviral, antibacterial, and antitumor responses. IFN-gamma Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived IFN-gamma protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IFN-gamma Protein, Mouse (HEK293, Fc) is 133 a.a., with molecular weight of ~55 kDa.

HY-P73254

	IFN-gamma Protein, Rat (HEK293, Fc) IFG; IFI; IFNG; IFN-gamma; Immune interferon; Interferon gamma	Rat	HEK293
	IFN-gamma (interferon-gamma) is a type II interferon produced by T cells and NK cells, which can significantly activate antibacterial, antiviral and antitumor responses.It acts through the JAK-STAT pathway and its receptor IFNGR1 to affect gene regulation.IFN-gamma Protein, Rat (HEK293, Fc) is the recombinant rat-derived IFN-gamma protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P74857

	IFN-gamma Protein, Ferret (HEK293, His) IFG; IFI; IFNG; IFN-gamma; Immune interferon; Interferon gamma	Others	HEK293
	IFN-gamma is a type II interferon derived from immune cells such as T cells and NK cells that crucially activates antibacterial, antiviral and antitumor responses through the JAK-STAT pathway and its receptor IFNGR1 .Binding opens the intracellular domain of IFNGR1, activating downstream components (JAK2, JAK1, STAT1), leading to STAT1 activation, nuclear translocation, and transcription of IFNG-regulated genes. IFN-gamma Protein, Ferret (HEK293, His) is the recombinant IFN-gamma protein, expressed by HEK293 , with C-His labeled tag.

HY-P700240AF

	*Animal-Free IFN-gamma Protein, Pig (His)* IFG; IFI; IFNG; IFN-gamma; Immune interferon; Interferon gamma	Pig	E. coli
	IFN-gamma (interferon-gamma) is a type II interferon produced by immune cells such as T cells and NK cells. It plays a key role in antibacterial, antiviral and anti-tumor responses by activating effector immune cells and enhancing antigen presentation. effect. Its main signaling pathway involves the JAK-STAT pathway that interacts with its receptor IFNGR1, affecting gene regulation. Animal-Free IFN-gamma Protein, Pig (His) is the recombinant pig-derived animal-FreeIFN-gamma protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IFN-gamma Protein, Pig (His) is 143 a.a., with molecular weight of ~17.7 kDa.

HY-P72246

	IFN-omega 1 Protein, Bovine (His-SUMO) IFNW1; IFNW; Interferon omega-1; IFN-omega-c1; Interferon alpha-II-1	Bovine	E. coli
	IFN-omega 1 protein is a member of the alpha/beta interferon family. IFN-omega 1 Protein, Bovine (His-SUMO) is the recombinant bovine-derived IFN-omega 1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of IFN-omega 1 Protein, Bovine (His-SUMO) is 172 a.a., with molecular weight of ~35.7 kDa.

HY-P76404

	IFN-alpha 7/IFNA7 Protein, Human (HEK293, Fc) Interferon alpha-7; IFN-alpha-7; Interferon alpha-J; LeIF J; IFN-alpha-J1	Human	HEK293
	IFN-alpha 7 (IFNA7), belongs to type I interferon family, is produced by macrophages with antiviral activities. IFN-alpha 7/IFNA7 Protein, Human (HEK293, Fc) contains 166 a.a. (C24-D189), produced in HEK293 cells with a N-terminal hFc-tag.

HY-P76405

	IFN-alpha 7/IFNA7 Protein, Human (P.pastoris, His) Interferon alpha-7; IFN-alpha-7; Interferon alpha-J; LeIF J; IFN-alpha-J1	Human	P. pastoris
	IFN-alpha 7 (IFNA7), belongs to type I interferon family, is produced by macrophages with antiviral activities. IFN-alpha 7/IFNA7 Protein, Human (P.pastoris, His) contains 166 a.a. (C24-D189), produced in P.pastoris yeast cells with a C-terminal His-tag.

HY-P78456

	IFN-gamma Protein, Human (HEK293, His-Avi) Interferon-gamma; Interferon-γ; interferon; gamma; IFG; IFI; IFN gamma	Human	HEK293
	IFN-gamma Protein is a dimeric soluble cytokine. It exerts antibacterial, antiviral and antitumor effects through JAK-STAT, mTOR, MAPK and PI3K/AKT signaling pathways. IFN-gamma Protein, Human (HEK293, His-Avi) is the recombinant human-derived IFN-gamma protein, expressed by HEK293 , with C-His, C-Avi labeled tag. The total length of IFN-gamma Protein, Human (HEK293, His-Avi) is 138 a.a., with molecular weight of 20-35 kDa.

HY-P73249

	IFN-alpha B/IFNA8 Protein, Cynomolgus (HEK293, Fc) IFNA8; IFN-alpha 8; Interferon alpha-B; Interferon alpha-B2; LeIF B	Cynomolgus	HEK293
	IFN-alpha B/IFNA8 protein is a member of the alpha/beta interferon family. IFN-alpha B/IFNA8 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived IFN-alpha B/IFNA8 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of IFN-alpha B/IFNA8 Protein, Cynomolgus (HEK293, Fc) is 166 a.a., with molecular weight of ~48 kDa.

HY-P75824

	IFN-gamma R1/CD119 Protein, Rat (HEK293, Fc) Interferon gamma receptor 1; IFN-gamma-R1; IFN-gamma-R-alpha; CD119; IFNGR1	Rat	HEK293
	IFN-gamma R1 (CD119), one of the subunit of IFN-gamma receptor, is a receptor for IFN-gamma. IFN-gamma R1 forms the functional receptor with IFN-gamma R2. Upon binding with IFN-gamma, IFN-gamma R1 and IFN-gamma R2 oligomerize and transphosphorylate. Then, JAK1 and JAK2 are phosphorylated and activated, and STAT1 is recruited to the receptor complex. Phosphorylated STAT1 translocates to the nucleus, where it regulates the expression of IFN-responsive genes (e.g. CD54). IFN-gamma R1/CD119 Protein, Rat (HEK293, Fc) is a recombinant mouse IFN-gamma R1 (M1-S241) with C-terminal hFc tag, which is produced in HEK293 cells.

HY-P72612A

	IFN-gamma R1/CD119 Protein, Human (HEK293, His) Interferon gamma receptor 1; IFN-gamma-R1; IFN-gamma-R-alpha; CD119; IFNgr1	Human	HEK293
	IFN-gamma R1 (CD119), one of the subunit of IFN-gamma receptor, is a receptor for IFN-gamma. IFN-gamma R1 forms the functional receptor with IFN-gamma R2. Upon binding with IFN-gamma, IFN-gamma R1 and IFN-gamma R2 oligomerize and transphosphorylate. Then, JAK1 and JAK2 are phosphorylated and activated, and STAT1 is recruited to the receptor complex. Phosphorylated STAT1 translocates to the nucleus, where it regulates the expression of IFN-responsive genes (e.g. CD54). IFN-gamma R1/CD119 Protein, Human (228a.a, HEK293, His) is a recombinant human IFN-gamma R1 (E18-G245) with C-terminal 6*His tag, which is produced in HEK293 cells.

HY-P72612

	IFN-gamma R1/CD119 Protein, Human (HEK293, His, solution) Interferon gamma receptor 1; IFN-gamma-R1; IFN-gamma-R-alpha; CD119; IFNgr1	Human	HEK293
	IFN-gamma R1 (CD119), one of the subunit of IFN-gamma receptor, is a receptor for IFN-gamma. IFN-gamma R1 forms the functional receptor with IFN-gamma R2. Upon binding with IFN-gamma,IFN-gamma R1 and IFN-gamma R2 oligomerize and transphosphorylate. Then, JAK1 and JAK2 are phosphorylated and activated, and STAT1 is recruited to the receptor complex. Phosphorylated STAT1 translocates to the nucleus, where it regulates the expression of IFN-responsive genes (e.g. CD54). IFN-gamma R1/CD119 Protein, Human (HEK293, His, solution) is a recombinant human IFN-gamma R1 (E18-G245) with C-terminal 6*His tag, which is produced in HEK293 cells.

HY-P700204AF

	*Animal-Free IFN-lambda 3/IL-28B Protein, Mouse (His)* IFN-λ3; IFL-1; INF-l; Interferon lambda-3; IFN-lambda-3; IL-28B; IFNl3	Mouse	E. coli
	The IFN-lambda 3/IL-28B protein is a cytokine with antiviral, antitumor, and immunomodulatory properties that is critical for defense against viruses, especially in epithelial tissues. It acts as a ligand for IL10RB and IFNLR1 receptor complexes, activating the JAK/STAT signaling pathway and inducing IFN-stimulated genes (ISG) into an antiviral state. Animal-Free IFN-lambda 3/IL-28B Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIFN-lambda 3/IL-28B protein, expressed by E. coli , with C-His labeled tag.

HY-P700611

	IFN-gamma R1/CD119 Protein, Human (HEK293, His-Flag) Interferon gamma receptor 1; IFN-gamma-R1; IFN-gamma-R-alpha; CD119; IFNgr1	Human	HEK293
	IFN-γ R1/CD119 is an important receptor subunit of interferon γ/INFG that activates effector immune cells and enhances antigen presentation, contributing to antibacterial, antiviral, and antitumor responses. It cooperates with IFNGR2 to form a functional receptor. IFN-gamma R1/CD119 Protein, Human (HEK293, His-Flag) is the recombinant human-derived IFN-gamma R1/CD119 protein, expressed by HEK293 , with C-6*His, C-Flag labeled tag.

HY-P73249A

	IFN-alpha B/IFNA8 Protein, Cynomolgus (HEK293, C-mFc) IFNA8; IFN-alpha 8; Interferon alpha-B; Interferon alpha-B2; LeIF B	Cynomolgus	HEK293
	IFN-alpha B/IFNA8 protein is a member of the alpha/beta interferon family. IFN-alpha B/IFNA8 Protein, Cynomolgus (HEK293, C-mFc) is the recombinant cynomolgus-derived IFN-alpha B/IFNA8, expressed by HEK293 , with C-mFc labeled tag. The total length of IFN-alpha B/IFNA8 Protein, Cynomolgus (HEK293, C-mFc) is 166 a.a.,

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Cat. No.	Product Name	Chemical Structure

HY-B1945S

DEHP-d4
DEHP-d₄ is the deuterium labeled DEHP. DEHP (Bis(2-ethylhexyl) phthalate) is an endogenous metabolite.

HY-W423530S

Bis(2-propylheptyl) phthalate-d4
Bis(2-propylheptyl) phthalate-d₄ (Phthalic acid bis(2-propylheptyl) ester-d₄) is a deuterium labeled compound.

HY-W585980S

Bis(2-butoxyethyl) 2-hydroxyethyl phosphate-d4
Bis(2-butoxyethyl) 2-hydroxyethyl phosphate-d₄ (Bis(2-butoxyethyl) 2-hydroxyethyl phosphate-d₄) is a deuterium labeled compound.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81111

	IFN gamma Antibody IFNG; IFG; IFI; IFN Gamma; IFN Immune; IFN-gamma; IFNG; IFNG_HUMAN; Immune Interferon; Interferon gamma; Interferon Gamma Precursor; Macrophage Activating Factor; MAF; T Cell Interferon; Type II Interferon.	WB, ICC/IF, FC	Human, Mouse, Rat
	IFN gamma Antibody is an unconjugated, approximately 19 kDa, rabbit-derived, anti-IFN gamma monoclonal antibody. IFN gamma Antibody can be used for: WB,ICC/IF,FC expriments in human, mouse,rat background without labeling.

HY-P81815

	Interferon beta Antibody (YA1560) Interferon beta; Interferon β; IFN-beta; IFN-β; IFNβ; Fibroblast interferon; IFB; IFNB	WB, IP	Human
	Interferon beta Antibody (YA1560) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1560), targeting Interferon beta, with a predicted molecular weight of 22 kDa (observed band size: 22 kDa). Interferon beta Antibody (YA1560) can be used for WB, IP experiment in human background.