TH - tyrosine hydroxylase Gene

Homo sapiens

Also known as TYH; DYT14; DYT5b

Gene ID: 7054 | Gene type: protein coding

About TH

Cytogenetic location: 11p15.5 Genomic coordinates (GRCh38): 11:2,163,929-2,171,815 (from NCBI)

This gene has 11 transcripts (splice variants), 188 orthologues, 3 paralogues and is associated with 3 phenotypes. Restricted expression toward adrenal (RPKM 42.8).

Summary

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting Enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

TH Products(3)

mRNA	Protein	Name
NM_000360.4	NP_000351.2	tyrosine 3-monooxygenase isoform b
NM_199292.3	NP_954986.2	tyrosine 3-monooxygenase isoform a
NM_199293.3	NP_954987.2	tyrosine 3-monooxygenase isoform c

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables enzyme binding	IPI IPI: Inferred from physical interaction	19703902	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	11943812	GOA
enables tyrosine 3-monooxygenase activity	IDA IDA: Inferred from direct assay	1680128	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in dopamine biosynthetic process	IDA IDA: Inferred from direct assay	12457228	GOA
involved in epinephrine biosynthetic process	IDA IDA: Inferred from direct assay	12457228	GOA
involved in norepinephrine biosynthetic process	IDA IDA: Inferred from direct assay	12457228	GOA
involved in response to ethanol	IDA IDA: Inferred from direct assay	18343820	GOA
involved in response to hypoxia	IDA IDA: Inferred from direct assay	17520326	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	10907721	GOA
located in cytoplasmic side of plasma membrane	IDA IDA: Inferred from direct assay	12457228	GOA
located in cytoplasmic vesicle	IDA IDA: Inferred from direct assay	12457228	GOA
located in melanosome membrane	IDA IDA: Inferred from direct assay	12631248	GOA
located in neuron projection	IDA IDA: Inferred from direct assay	17135716	GOA
located in nucleus	IDA IDA: Inferred from direct assay	21392500	GOA
located in smooth endoplasmic reticulum	IDA IDA: Inferred from direct assay	12457228	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TH Protein Structure

TOH_N

Biopterin_H

0
100
200
300
400
500
528 a.a.

Protein Preferred Names

Protein Names

tyrosine 3-monooxygenase

dystonia 14

Recombinant TH Proteins

Cat. No.	Product Name	Accession	Purity
HY-P73564	Tyrosine Hydroxylase Protein, Human (sf9, His)	P07101-3 (P2-G497)	≥95%

Related Diseases

Diseases

Alias

Segawa Syndrome, Autosomal Recessive

Tyrosine Hydroxylase Deficiency	Dystonia, Dopa-Responsive, Autosomal Recessive
Parkinsonism, Infantile, Autosomal Recessive	Segawa Syndrome, Recessive
Dyt5b	Th-Deficient Drd
Tyrosine Hydroxylase-Deficient Dopa-Responsive Dystonia	Autosomal Recessive Infantile Parkinsonism
Autosomal Recessive Dopa-Responsive Dystonia	Autosomal Recessive Dopa Responsive Dystonia
Dopa-Responsive Dystonia, Autosomal Recessive	Dopa Responsive Dystonia, Autosomal Recessive
Dyt/Park-Th	Dystonia, Dopa Responsive, Autosomal Recessive
Th Deficiency	Autosomal Recessive Segawa Syndrome
Thy	Segawa Syndrome Autosomal Recessive
ARSEGS	Thd
Dystonia, Dopa-Responsive, With Or Without Hyperphenylalaninemia, Autosomal Recessive

Dystonia

Dystonic Disease	Dystonic Disorder
Dystonia Disorders	Neuroleptic Dyskinesia

Dystonia, Dopa-Responsive

Dystonia 5	Dopa-Responsive Dystonia
DRD	Dyt5
Dystonia-Parkinsonism With Diurnal Fluctuation	Dyt-Th
Hpd With Diurnal Fluctuation	Hereditary Progressive Dystonia With Diurnal Fluctuation
Dystonia, Progressive, With Diurnal Variation	Segawa Syndrome, Autosomal Dominant
Dystonia, Dopa-Responsive, Autosomal Dominant	Dopa-Responsive Dystonia, Autosomal Dominant
Dystonia, Dopa-Responsive, With Or Without Hyperphenylalaninemia	Dyt-Gch1
Dyt-Spr	Dystonia 5, Dopa-Responsive Type
Hereditary Progressive Dystonia With Marked Diurnal Fluctuation	Autosomal Dominant Dopa-Responsive Dystonia
Autosomal Dominant Segawa Syndrome	Dystonia-5
Progressive Dystonia With Diurnal Fluctuation	Dystonia, Type 5, Dopa-Responsive Type

Placental Insufficiency

Uteroplacental Vascular Insufficiency

Hyperphenylalaninemia, Bh4-Deficient, B

Gtp Cyclohydrolase I Deficiency	HPABH4B
Hyperphenylalaninemia, Tetrahydrobiopterin-Deficient, Due To Gtp Cyclohydrolase I Deficiency	Bh4-Deficient Hyperphenylalaninemia B
Gtp Cyclohydrolase 1 Deficiency	Tetrahydrobiopterin-Deficient Hyperphenylalaninemia B
Hyperphenylalaninemia, Tetrahydrobiopterin-Deficient, Due To Gtp Cyclohydrolase 1 Deficiency	Gtpch Deficiency
Hyperphenylalaninemia Due To Gtp Cyclohydrolase Deficiency	Atypical Severe Phenylketonuria Due To Gtp Cyclohydrolase I Deficiency
Gch1 Deficiency	Guanosine Triphosphate Cyclohydrolase I Deficiency
Hyperphenylalaninemia With Neopterin Deficiency

Phenylketonuria

Phenylalanine Hydroxylase Deficiency	PKU
Pah Deficiency	Folling Disease
Maternal Phenylketonuria	Phenylketonurias
Oligophrenia Phenylpyruvica	Hyperphenylalaninemia, Non-Pku Mild
Folling'S Disease	Phenylalaninemia
Mild Phenylketonuria	Mild Pku
Variant Pku	Variant Phenylketonuria
Mpku	Deficiency Disease, Phenylalanine Hydroxylase
Phenylketonuria, Maternal	Phenylalanine Hydroxylase Deficiency Disease
Hyperphenylalaninemic Embryopathy	Maternal Pku
Maternal Hyperphenylalaninemia	Phenylketonuric Embryopathy
Hyperphenylalaninemia	HPA
Non-Phenylketonuria Hyperphenylalaninemia	NON-PKU HPA
Phenylketonuria Maternal	Classical Phenylketonuria
Hyperphenylalaninaemia	Pku - [Phenylketonuria]

Mood Disorder

Mood Disorders

Episodic Mood Disorder

Parkinsonism

Parkinsonism-Plus	Idiopathic Parkinsonism
Primary Parkinsonism	Paralysis Agitans Syndrome
Parkinsonian Syndrome	Trembling Paralysis
Paralysis Agitans	Shaking Palsy
Shaking Paralysis

Pheochromocytoma

Pheochromocytoma, Susceptibility To	Phaeochromocytoma
Adrenal Gland Chromaffin Paraganglioma	Adrenal Gland Chromaffinoma
Adrenal Gland Paraganglioma	Adrenal Gland Pheochromocytoma
Chromaffin Paraganglioma Of The Adrenal Gland	Intraadrenal Paraganglioma
PCC	Chromaffin Cell Tumor
Medullary Chromaffinoma	Medullary Paraganglioma
Pheochromoblastoma	Pheochromocytomas
Chromaffin Cell Neoplasm	Pheochromocytoma, Malignant

Sudden Infant Death Syndrome

SIDS	Sudden Infant Death Syndrome, Susceptibility To
Cot Death	Crib Death
Sudden Death Of Nonspecific Cause In Infancy	Sudden Infant Death
Death, Sudden, Syndrome, Infant

Multiple System Atrophy 1

Multiple System Atrophy	Shy-Drager Syndrome
Msa	MSA1
Multiple System Atrophy 1, Susceptibility To	Sporadic Olivopontocerebellar Atrophy
Multisystem Atrophy	Msa1, Susceptibility To
Multiple System Atrophy, Susceptibility To	Opca
Progressive Autonomic Failure With Multiple System Atrophy	Sds

Dementia, Lewy Body

Lewy Body Dementia	Lewy Body Disease
Diffuse Lewy Body Disease	Dementia With Lewy Bodies
DLB	Autosomal Dominant Diffuse Lewy Body Disease
Cortical Lewy Body Disease	Dementia, Lewy Body, Susceptibility To
Lewy Body Dementia, Susceptibility To	Senile Dementia Of The Lewy Body Type
Dementia Of The Lewy Body Type	Lbd
Diffuse Lewy Body Disease With Gaze Palsy	Dysphasic Dementia Hereditary
Lewy Body Type Senile Dementia	Lewy Body Variant Of Alzheimer Disease
Lewy Bodies	Lewy Body
Dlbd - [Diffuse Lewy Body Disease]	Clbd - [Cortical Lewy Body Disease]

Paraganglioma

Chemodectoma	Glomus Body Tumor
Paragangliomas	Carotid Body Paraganglioma
Extra-Adrenal Paraganglioma

Stiff-Person Syndrome

SPS	Stiff-Man Syndrome
Stiff Man Syndrome	Stiff Person Syndrome
Moersch-Woltman Syndrome	Sms
Stiff-Trunk Syndrome	Morsch Woltman Syndrome
Stiff Person Syndrome And Related Disorders	Stiff Person Spectrum Disorder
Classic Stiff Person Syndrome	Classic Sps
Focal Stiff Limb Syndrome	Focal Stiff-Person Syndrome
Stiff Leg Syndrome	Progressive Encephalomyelitis With Rigidity

Parkinson Disease, Late-Onset

Parkinson Disease	Parkinson'S Disease
PD	PARK
Parkinson Disease, Susceptibility To	Late Onset Parkinson'S Disease
Late Onset Parkinson Disease	Paralysis Agitans
Primary Parkinsonism	Idiopathic Parkinson Disease
Parkinson'S	Parkinson Disease, Late-Onset, Susceptibility To
Parkinson Disease, Age Of Onset, Modifier	Lewy Body Parkinson Disease
Idiopathic Parkinson'S Disease	Pd - [Parkinson Disease]
Parkinson Disease Nos	Parkinson, Nos
Primary Parkinson Disease

Ganglioglioma

Childhood Ganglioglioma	Adult Ganglioglioma
Cns Ganglioglioma	Mixed Cell Tumors Containing Both Neural Ganglionic Cells And Neural Glial Cell Components

Gilles De La Tourette Syndrome

Tourette Syndrome	Tourette Disorder
GTS	Ts
Gilles De La Tourette'S Syndrome	Motor-Verbal Tic Disorder
Guinon'S Disease	Psychogenic Tics
Tourette'S Syndrome	Chronic Motor And Vocal Tic Disorder
Td	Tourette'S Disease
Combined Vocal And Multiple Motor Tic Disorder [De La Tourette]	Combined Vocal And Multiple Motor Tic Disorder
Tic De La Tourette

Bipolar Disorder

Bipolar Depression	Manic Disorder
Depression, Bipolar	Bipolar Disorder Manic Phase
Depressive-Manic Psych.	Manic Bipolar Affective Disorder
Manic Bipolar I Disorder	Manic Depression
Manic Depressive Disorder	Mixed Bipolar Disorder
Bipolar Affective Disorder	Bipolar Affective Psychosis
Bipolar Spectrum Disorder	Manic Depressive Illness
Depression Bipolar	Bipolar Disorder, Mixed
Major Affective Disorder	Major Affective Disorder 1
Major Affective Disorder 2

Wolfram Syndrome

Didmoad Syndrome	Didmoad
Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness	Wfs
Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, And Deafness	Didmoadud
Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Deafness Syndrome	Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Hearing Loss Syndrome

Rett Syndrome

Atypical Rett Syndrome	RTT
Rett Disorder	Rts
Autism, Dementia, Ataxia, And Loss Of Purposeful Hand Use	Rett Syndrome, Preserved Speech Variant
Rett Syndrome, Atypical	Rett'S Disorder
Rett Syndrome Variant	Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use Syndrome
Cerebroatrophic Hyperammonemia	Rett Like Syndrome
Rett'S Syndrome	Atypical Rtt
Autism-Dementia-Ataxia-Loss Of Purposeful Hand Use	Rett Syndrome Preserved Speech Variant
Rett Syndrome Zappella Variant	Rett Syndrome, Zappella Variant

Von Hippel-Lindau Syndrome

Von Hippel-Lindau Disease	Vhl
Vhl Syndrome	VHLS
Von Hippel-Lindau Syndrome, Modifier Of	Hippel Lindau Syndrome
Angiomatosis Retinae	Cerebelloretinal Angiomatosis, Familial
Hippel-Lindau Disease	Familial Cerebelloretinal Angiomatosis
Lindau Disease	VHLD

Movement Disease

Movement Disorders

Movement Disorder

Constipation

Multiple Endocrine Neoplasia

Men	Multiple Endocrine Adenomatosis
Multiple Endocrine Neoplasia Syndrome	Adenomatosis, Familial Endocrine
Endocrine Neoplasia, Multiple	Familial Endocrine Adenomatosis
Mea	Multiple Endocrine Neoplasms
Multiple Endocrine Neoplasia Type 1

Supranuclear Palsy, Progressive, 1

Progressive Supranuclear Palsy	Steele-Richardson-Olszewski Syndrome
Supranuclear Palsy, Progressive	Progressive Supranuclear Ophthalmoplegia
Psp	PSNP1
Familial Progressive Supranuclear Palsy	Richardson'S Syndrome
Psp Syndrome	Progressive Supranuclear Palsy 1
Supranuclear Palsy Progressive	Ophthalmoplegia, Supranuclear, Progressive
Steele-Richardson-Olszewksi Syndrome

Ganglioneuroblastoma

Borderline Personality Disorder

Personality Disorder

Personality Disorders	Character Disorder
Personality	Specific Personality Disorders
Enduring Personality Change After Psychiatric Illness

Toxic Encephalopathy

Neurotoxicity	Neurotoxicity Syndromes
Neurotoxicity Syndrome	Encephalopathy, Toxic

Dopamine Beta-Hydroxylase Deficiency

Noradrenaline Deficiency	Norepinephrine Deficiency
Dopamine Beta Hydroxylase Deficiency	Congenital Dopamine Beta-Hydroxylase Deficiency
Dopamine Beta-Hydroxylase Deficiency, Congenital	Dopamine Β-Hydroxylase
Dbh Deficiency

Gastroparesis

Gastroparesis Syndrome	Delayed Gastric Emptying
Gastric Atonia	Gastroparalysis

Central Hypoventilation Syndrome, Congenital, 1

Cchs	CCHS1
Central Hypoventilation Syndrome, Congenital, 1, With Or Without Hirschsprung Disease	Central Hypoventilation Syndrome, Congenital
Congenital Failure Of Autonomic Control	Autonomic Control, Congenital Failure Of
Ondine Curse, Congenital	Ondine Curse
Central Hypoventilation Syndrome, Congenital, 1, With Or Without Hirschsprung	Hypoventilation, Central, Syndrome, Congenital, Type 1
Congenital Central Hypoventilation	Sleep Apnea, Central
Central Alveolar Hypoventilation Syndrome	Cchs With Hirschsprung Disease
Congenital Central Alveolar Hypoventilation Syndrome	Sleep-Related Respiratory Failure
Hypoventilation

Ganglioneuroma

Amphetamine Abuse

Aromatic L-Amino Acid Decarboxylase Deficiency

Aadc Deficiency	Dopa Decarboxylase Deficiency
Ddc Deficiency	Aromatic Amino Acid Decarboxylase Deficiency
Deficiency Of Aromatic-L-Amino-Acid Decarboxylase	AADCD
Aromatic-L-Amino-Acid Decarboxylase Deficiency	Aromatic L-Amino-Acid Decarboxylase Deficiency

Hydrocephalus Due To Congenital Stenosis Of Aqueduct Of Sylvius

Aqueductal Stenosis	Aqueductal Stenosis, X-Linked
Hsas	Hsas1
Hycx	Hydrocephalus, X-Linked
Xlas	X-Linked Hydrocephalus Syndrome

Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder	ADHD
Attention Deficit Disorder	Attention Deficit-Hyperactivity Disorder, Susceptibility To
Attention Deficit Disorder With Hyperactivity	Hyperkinetic Disorder
Hyperactivity Of Childhood	Attention-Deficit/Hyperactivity Disorder
Add	Addh
Attention Deficit	Attention Deficit Disorder Of Childhood With Hyperactivity
Attention Deficit Disorder With Hyperactivity Syndrome	Hyperkinetic Syndrome
Attention-Deficit Hyperactivity Disorder	Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type
Disturbance Of Activity And Attention	Disorder Of Activity And Attention
Adhd - [Attention Deficit Hyperactivity Disorder]	Hyperkinetic Disorders
Disorder Of Activity And Attention With Hyperkinesia	Attention Deficit Syndrome With Hyperactivity

Dystonia, Dopa-Responsive, Due To Sepiapterin Reductase Deficiency

Sepiapterin Reductase Deficiency	Spr Deficiency
Dopa-Responsive Dystonia Due To Sepiapterin Reductase Deficiency	Srd
Drd Due To Srd	Dopa-Responsive Hypersomnia
Dyt-Spr	Dyt/Park-Spr
Sr-Deficient Drd	Autosomal Recessive Sepiapterin Reductase-Deficient Drd
Spr	DRDSPRD
Motor And Cognitive Disorder Due To Sepiapterin Reductase Deficiency	Psychomotor Disorders

Hyperphenylalaninemia, Bh4-Deficient, A

6-Pyruvoyl-Tetrahydropterin Synthase Deficiency	Pts Deficiency
HPABH4A	Hyperphenylalaninemia, Tetrahydrobiopterin-Deficient, Due To Pts Deficiency
Ptsd	Bh4-Deficient Hyperphenylalaninemia A
Hyperphenylalaninemia Due To 6-Pyruvoyltetrahydropterin Synthase Deficiency	Tetrahydobioperin-Deficient Hyperphenylalaninemia Due To Pts Deficiency
Hyperphenylalanemia, Bh4-Deficient, A	Hyperphenylalaninemia Due To 6-Pyruvoyl-Tetrahydropterin Synthase Deficiency
6-Pyruvoyltetrahydropterin Synthase Deficiency	Hyperphenylalaninemia Tetrahydrobiopterin-Deficient Due To Pts Deficiency
Ptpsd	Hyperphenylalaninemia, Bh4-Deficient, Type A

Adjustment Disorder

Adjustment Reaction	Adjustment Disorders
Adjustment Disease	Brief Situational Non-Psychotic Disorder
Adaptation Reaction Nos	Emotional Crisis
Situational Disorder	Situational Disturbance
Situational Maladjustment	Situational Reaction
Situational Reaction With Maladjustment	Transient Situational Disturbance

Autoimmune Polyendocrine Syndrome, Type I, With Or Without Reversible Metaphyseal Dysplasia

APS1	Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy
Apeced	Pga I
Hypoadrenocorticism With Hypoparathyroidism And Superficial Moniliasis	Autoimmune Polyendocrinopathy Syndrome , Type I, With Or Without Reversible Metaphyseal Dysplasia
Polyglandular Autoimmune Syndrome, Type 1	Autoimmune Polyglandular Syndrome Type 1
Autoimmune Polyendocrine Syndrome Type 1	Autoimmune Polyendocrinopathy Syndrome Type 1
Whitaker Syndrome	Aps Type 1
Polyglandular Type I Autoimmune Syndrome	Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Syndrome
Aps I	Autoimmune Polyglandular Syndrome, Type I
Polyglandular Autoimmune Syndrome, Type I	Aps 1
Autoimmune Polyglandular Syndrome Type I	Pga 1
Pga-I	Polyglandular Autoimmune Syndrome Type 1
Type I Polyglandular Autoimmune Syndrome	Aire Deficiency
Autoimmune Polyendocrinopathy With Candidiasis And Ectodermal Dystrophy	Autoimmune Polyglandular Syndrome, Type 1
Autoimmune Polyendocrinopathy Type 1	Apeced Syndrome
Autoimmune Hypoparathyroidism-Chronic Candidiasis-Addison Disease Syndrome	Ham Syndrome
Hypoparathyroidism-Addison Disease-Mucocutaneous Candidiasis Syndrome	Medac Syndrome
Multiple Endocrine Deficiency-Addison Disease-Candidiasis Syndrome	Autoimmune Polyendocrine Syndrome 1, With Or Without Reversible Metaphyseal Dysplasia
Aps-1	Autoimmune Polyendocrine Syndrome Type I
Autoimmune Polyendocrinopathy Syndrome Type I	Autosomal Dominant Autoimmune Polyendocrinopathy Syndrome Type I
Polyglandular Autoimmune Syndrome Type I	Polyglandular Deficiency Syndrome Persian-Jewish Type
Autoimmune Polyendocrinopathy Syndrome, Type I, Autosomal Dominant	Polyendocrinopathy Autoimmune, Type 1, With/Without Reversible Metaphyseal Dysplasia

Hyperphenylalaninemia

Hyperphenylalaninaemia

Schizophrenia

SCZD	Schizophrenia With Or Without An Affective Disorder
Schizophrenia 12	Schizophrenia, Susceptibility To
Schizophrenia-1	Dementia Praecox
Schizophrenia 1

Dementia

Dementias	Presenile Dementia
Alzheimer Type Dementia	Alzheimer Sclerosis
Alzheimer Disease Dementia	Alzheimer Dementia
Primary Degenerative Alzheimer Type Dementia	End Stage Alzheimer'S Dementia
Alzheimer'S Type Atypical Dementia	Alzheimer Type Presenile Dementia
Early Onset Alzheimer Dementia	Dementia In Alzheimer Disease Type 2
Dementia In Alzheimer Disease With Early Onset	Early Onset Alzheimer Type Dementia, Uncomplicated
Primary Degenerative Alzheimer Type Dementia, Early Onset	Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated
Alzheimer Disease Dementia With Early Onset	Presenile Sclerosis
Presenile Brain Sclerosis	Presenile Alzheimer Brain Sclerosis
Late Onset Alzheimer Dementia	Dementia In Alzheimer Disease Type 1
Dementia In Alzheimer Disease With Late Onset	Primary Degenerative Alzheimer Type Dementia, Late Onset
Sdat - [Senile Dementia, Alzheimer Type]	Alzheimer Disease Dementia With Late Onset
Late Onset Alzheimer Brain Sclerosis	Senile Alzheimer Brain Disease
Senile Alzheimer Brain Sclerosis	Senile Primary Degenerative Alzheimer Type Dementia
Senile Dementia Of The Alzheimer Type	Arteriosclerotic Dementia
Strategic-Infarct Dementia	Post Stroke Dementia
Vascular Cognitive Impairment	Vascular Dementia
Dementia Of The Lewy Body Type	Dementia With Lewy Bodies
Sdlt - [Senile Dementia Of The Lewy Body Type]	Senile Dementia Of The Lewy Body Type
Alcohol-Related Dementia	Alcoholic Dementia Nos
Alcohol-Induced Dementia	Alcoholic Brain Syndrome
Chronic Alcoholic Brain Syndrome	Alcohol Dementia
Late Onset Alcoholic Psychosis	Residual And Late-Onset Alcohol-Induced Psychotic Disorder
Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder	Late-Onset Psychoactive Substance-Induced Psychotic Disorder
Inhalant Dementia	Volatile Solvents Dementia
Dementia In Paralysis Agitans	Pdd - [Parkinson Disease Dementia]
Dementia Syndrome Of Parkinson Disease	Dementia In Parkinson Disease
Parkinson Related Dementia	Dementia In Huntington Chorea
Hiv - [Human Immunodeficiency Virus] Dementia	Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex
Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex	Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex
Aids Related Dementia	Dementia Due To Niacin Deficiency

Rhabdomyosarcoma 2

Alveolar Rhabdomyosarcoma	Rhabdomyosarcoma, Alveolar
Rhabdomyosarcoma Alveolar	RMS2
Rmsa	Rhabdomyosarcoma 2, Alveolar
Alveolar Childhood Rhabdomyosarcoma	Arms
Rhabdomyosarcoma, Type 2

Major Depressive Disorder

Seasonal Affective Disorder	Unipolar Depression
Depression	MDD
Depressive Disorder	Unipolar Depression, Susceptibility To
Major Depressive Disorder 1	Major Depressive Disorder, Response To Citalopram Therapy In
Major Depressive Disorder 2	Winter Depression
Single Major Depressive Episode	Sad
Clinical Depression	Major Depression
Depressive Syndrome	Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment
Seasonal Affective Disorder, Susceptibility To	Recurrent Major Depression
Affective Disorder, Seasonal	Depression In A Seasonal Pattern
Depression	Seasonal
Major Depressive Disorder With A Seasonal Pattern	Seasonal Depression
Seasonal Mood Disorder	Mental Depression
Recurrent Major Depressive Episodes

Peripheral Nervous System Benign Neoplasm

Autonomic Nervous System Benign Neoplasm

Alcohol Dependence

Alcoholism	Alcohol Dependence, Susceptibility To
Alcohol Dependence, Protection Against	Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against
Alcoholism, Susceptibility To	Alcoholic Intoxication, Chronic
Pharyngeal Neoplasms	Chronic Alcoholism
Dipsomania	Alcohol Addiction
Ethanol Dependence	Chronic Ethanolism
Chronic Alcoholic Disease Nos	Alcoholic Disease Nos
Alcoholic

Striatonigral Degeneration

Oculogyric Crisis

Postencephalitic Parkinson Disease

Postencephalitic Parkinsonism

Parkinson Disease, Postencephalitic

Neonatal Hypoxic And Ischemic Brain Injury

Perinatal Asphyxia	Hypoxic-Ischemic Encephalopathy
Perinatal Hypoxia	Hie
Hypoxic And Ischemic Brain Injury In The Newborn	Encephalopathy, Hypoxic Ischemic
Encephalopathies Hypoxic-Ischemic	Hypoxic Ischemic Encephalopathy
Hypoxic Ischaemic Brain Injury	Brain Hypoxia
Cerebral Hypoxia	Hypoxic Encephalopathy
Hypoxic Brain Damage	Hypoxic Brain Injury
Brainstem Hypoxia	Hypoxic Brainstem Damage

Psychotic Disorder

Psychotic Disorders	Mental Or Behavioural Disorder
Psychotic	Mental Disorders

Anxiety

Anxiety Disorder	Anxiety Disorders
Anxiety State	Anxieties
Anxiety Neurosis

Diabetic Autonomic Neuropathy

Diabetic Neuropathies

Morphine Dependence

Neuroblastoma

Nb	Neuroblastoma, Susceptibility To
Neuroblastomas	Central Neuroblastoma

Beckwith-Wiedemann Syndrome

Wiedemann-Beckwith Syndrome	BWS
Exomphalos-Macroglossia-Gigantism Syndrome	Emg Syndrome
Beckwith-Wiedemann Syndrome Due To Cdkn1c Mutation	Emg Abnormality
Wbs	Exomphalos Macroglossia Gigantism Syndrome
Beckwith-Wiedemann Syndrome Due To Nsd1 Mutation	Macroglossia Exomphalos Gigantism

Impulse Control Disorder

Disruptive, Impulse Control, And Conduct Disorders

Huntington Disease

Huntington'S Disease	Huntington Chorea
Huntington'S Chorea	HD
Huntington Chronic Progressive Hereditary Chorea	Juvenile Huntington Disease
Chronic Progressive Chorea	Chronic Progressive Hereditary Chorea
Hc - [Huntington Chorea]	Hereditary Chorea
Progressive Hereditary Chorea

Congenital Central Hypoventilation Syndrome

Cchs	Haddad Syndrome
Ondine Curse	Ondine Syndrome
Congenital Central Hypoventilation	Congenital Central Alveolar Hypoventilation Syndrome
Congenital Failure Of Autonomic Control	Ondine'S Curse
Primary Alveolar Hypoventilation	Ondine-Hirschsprung Disease
Central Congenital Hypoventilation Syndrome	Congenital Ondine Curse
Idiopathic Congenital Central Alveolar Hypoventilation	Congenital Central Alveolar Hypoventilation-Hirschsprung Disease Syndrome
Ondine-Hirschsprung Syndrome

Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex 1

Guam Disease	Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex Of Guam
Als-Pdc	Lytico-Bodig Disease
Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Complex	Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex 1, Susceptibility To
Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex, Susceptibility To	Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex
Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Of Guam Syndrome	Parkinsonism-Dementia-Als Complex
Pdals	Amyotrophic Lateral Sclerosis, Parkinsonism/Dementia Complex Of Guam
Parkinson-Dementia Complex Of Guam	G-Pdc
Guam Parkinsonism-Dementia Complex	ALS-PDC1
Als/Pdc Of Guam	Amyotrophic Lateral Sclerosis
Sclerosis, Lateral, Amyotrophic/Parkinsonism/Dementia Complex 1	Amyotrophic Lateral Sclerosis, Guam Form
Parkinsonian Disorders

Hypertension, Essential

Essential Hypertension	Hypertension
High Blood Pressure	Hypertension, Essential, Susceptibility To
Hypertensive Disease	Primary Hypertension
EHT	Hypertension, Salt-Sensitive Essential, Susceptibility To
Hyperpiesia	Idiopathic Hypertension
Hypertensive Disorder	Hypertension, Essential, Susceptibility To, 3
Hypertension, Essential 3	Hypertension, Essential, Salt-Sensitive
Hypertension, Essential, Susceptibility To, 6	Hypertension, Essential 6
Hypertension, Salt-Sensitive Essential	Hypertension, Susceptibility To
Hypertension, Essential, Susceptibility To, 4	Hypertension, Essential 4
Hypertension, Essential, Susceptibility To, 2	Hypertension, Essential 2
Hypertension, Essential, Susceptibility To, 1	Hypertension, Essential 1
Hypertension, Essential, Susceptibility To, 5	Hypertension, Essential 5
Htn	Vascular Hypertensive Disorder
Systemic Primary Arterial Hypertension	Hbp - [High Blood Pressure]
Systemic Arterial Hypertensive Disorder	Elevated Blood Pressure
Arterial Hypertension Nos	Hypertension Nos
Benign Hypertension	Systemic Arterial Hypertension
Systemic Hypertension	Artery Htn
Benign Htn	Vascular Htn
Vascular Hypertension	Cholesterol Hypertension
Cholesterol Htn	Idiopathic Htn
Malignant Hypertension	Malignant Htn
Raised Blood Pressure	Cardiovascular Hypertension
Primary Htn - [Hypertension]	High Arterial Tension
High Blood Pressure Disorder	Ht - [Hypertension]
Htn - [Hypertension]	Hypertensive Vascular Disease
Hypertensive Vascular Degeneration

Developmental And Epileptic Encephalopathy 47

DEE47	Epileptic Encephalopathy, Early Infantile, 47
Eiee47	Developmental And Epileptic Encephalopathy, 47
Early Infantile Epileptic Encephalopathy 47

Sleep Disorder

Sleep Disorders

Non-Organic Sleep Disorder

Dissociated Nystagmus

Autonomic Nervous System Disease

Autonomic Nervous System Dysfunction	Autonomic Nervous System Disorders
Autonomic Nervous System Disorder	Autonomic Nervous System Diseases
Abnormality Of The Autonomic Nervous System

Hearing Loss, Noise-Induced

Noise-Induced Hearing Loss	NIHL
Hearing Loss, Noise-Induced, Susceptibility To	Hearing Loss Noise-Induced
Noise Induced Hearing Loss

Esophageal Atresia

Tracheoesophageal Fistula	Congenital Atresia Of Esophagus
Congenital Imperforate Esophagus	Imperforate Esophagus
Oesophageal Atresia	Te Fistula
Tef	Tracheoesophageal Fistula With Or Without Esophageal Atresia

Parkinson Disease 4, Autosomal Dominant

Autosomal Dominant Parkinson Disease 4	PARK4
Parkinson Disease 4, Autosomal Dominant Lewy Body	Parkinson Disease 4
Parkinson'S Disease 4	Autosomal Dominant Lewy Body Parkinson Disease 4
Autosomal Dominant Parkinson'S Disease 4	Parkinson Disease 4 Autosomal Dominant Lewy Body
Parkinson Disease Autosomal Dominant 4	Parkinson Disease Familial Type 4
Parkinson Disease, Type 4

Autonomic Nervous System Neoplasm

Tumor Of Autonomic Nervous System

Alzheimer Disease, Familial, 1

Alzheimer Disease	Alzheimer'S Disease
Presenile And Senile Dementia	AD1
Alzheimer Disease, Susceptibility To	Alzheimer Disease, Late-Onset, Susceptibility To
Alzheimer Disease 1, Familial	AD
Familial Alzheimer Disease	Alzheimer Disease, Late-Onset
Alzheimers Dementia	Alzheimer Dementia
Alzheimer Sclerosis	Alzheimer Syndrome
Alzheimer-Type Dementia	Dat
Primary Senile Degenerative Dementia	Sdat
Alzheimer Disease 1	Autosomal Dominant Alzheimer Disease
Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy	Late Onset Alzheimer Disease
Alzheimers Disease	Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy
Late-Onset Alzheimers Disease	Alzheimer'S Disease Pathway Kegg
Dementia Due To Alzheimer'S Disease	Alzheimer Disease Type 1
Alzheimers

Peripheral Nervous System Neoplasm

Peripheral Nervous System Neoplasms	Nerve Sheath Neoplasm
Neoplasm Of Peripheral Nerve	Tumor Of Pns
Nerve Sheath Neoplasms	Nerve Sheath Tumors

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis	ALS
Lou Gehrig Disease	Amyotrophic Lateral Sclerosis Type 1
Charcot Disease	ALS1
Amyotrophic Lateral Sclerosis, Susceptibility To	Fals
Lou Gehrig'S Disease	Mnd
Motor Neuron Disease	Familial Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 1, Familial	Amyotrophic Lateral Sclerosis 1, Autosomal Dominant
Motor Neuron Disease, Bulbar	Motor Neurone Disease
Amyotrophic Lateral Sclerosis With Dementia	Dementia With Amyotrophic Lateral Sclerosis
Motor Neuron Disease, Amyotrophic Lateral Sclerosis	Sclerosis, Lateral, Amyotrophic
Sclerosis, Lateral, Amyotrophic, Type 1	Amyotrophic Sclerosis
Als - [Amyotrophic Lateral Sclerosis]	Wasting Palsy
Amyotrophic Paralysis	Amyotrophy Lateral Sclerosis
Wasting Paralysis	Spinal Progressive Amyotrophy
Progressive Atrophic Paralysis

Disease Of Mental Health

Mental Health

Mental Disorders

Choreatic Disease

Chorea

Hereditary Chorea

Specific Developmental Disorder

Peripheral Nervous System Disease

Peripheral Neuropathy	Peripheral Nerve Disease
Peripheral Nerve Disorders	Neuropathy, Peripheral
Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation

Stroke, Ischemic

Cerebral Infarction	Stroke
Ischemic Stroke	Cerebrovascular Accident
Cerebral Infarction, Susceptibility To	Stroke, Ischemic, Susceptibility To
Cerebral Infarct	Ischemic Stroke, Susceptibility To
Stroke, Susceptibility To	Cva - Cerebral Infarction
ISCHSTR	Ischemic Cerebrovascular Accident

Type 2 Diabetes Mellitus

Insulin Resistance	NIDDM
Type 2 Diabetes	Diabetes Mellitus, Non-Insulin-Dependent
T2D	Noninsulin-Dependent Diabetes Mellitus
Diabetes Mellitus, Type Ii	Maturity-Onset Diabetes
Insulin Resistance, Severe, Digenic	Diabetes Mellitus, Type 2
Diabetes Mellitus, Noninsulin-Dependent	Diabetes Mellitus, Noninsulin-Dependent, Association With
Diabetes Mellitus, Noninsulin-Dependent, Late Onset	Hypertension, Insulin Resistance-Related, Susceptibility To
Insulin Resistance, Susceptibility To	Non-Insulin-Dependent Diabetes Mellitus
Type Ii Diabetes Mellitus	Adult-Onset Diabetes Mellitus
Maturity-Onset Diabetes Mellitus	Diabetes Mellitus Type 2
Type Ii Diabetes	Type 2 Diabetes Mellitus, Susceptibility To
Diabetes, Type 2	Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To
Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To	Diabetes Mellitus, Type 2, Susceptibility To
Diabetes Mellitus, Noninsulin-Dependent, 2	Diabetes Mellitus, Type Ii, Susceptibility To
Hypertension, Insulin Resistance-Related	Adult-Onset Diabetes
Aodm	Diabetes Mellitus, Adult-Onset
Diabetes Mellitus Type Ii	Diabetes Mellitus Type 2, Susceptibility To
Diabetes, Type Ii, Susceptibility To	Diabetes Type 2
Diabetes Mellitus	Adult Onset Diabetes
Maturity Onset Diabetes	Nonketotic Diabetes
Non-Insulin Dependent Diabetes Mellitus	T2dm - [Type 2 Diabetes Mellitus]
Niddm - [Non Insulin Dependent Diabetes Mellitus]	Dm2
Dm Type Ii	Diabetic Type 2
Insulin Requiring Type 2 Diabetes	Noninsulin Dependent Diabetes
Non-Insulin-Dependent Diabetes Mellitus Without Complications	Diabetes Due To Insulin Secretory Defect
Diabetes Mellitus Due To Insulin Secretory Defect	Non-Insulin-Dependent Diabetes Of The Young
Senile Diabetes	Nonketotic Hyperglycaemia
Stable Diabetes

Nervous System Disease

Abnormality Of The Nervous System	Nervous System Diseases
Nervous System Disorder

Hirschsprung Disease 1

Hirschsprung Disease	Aganglionic Megacolon
Hscr	Hirschsprung'S Disease
Congenital Megacolon	Congenital Intestinal Aganglionosis
Colonic Aganglionosis	Hirschsprung Disease, Susceptibility To, 1
Hirschsprung Disease, Protection Against	HSCR1
Mgc	Pelvirectal Achalasia
Total Intestinal Aganglionosis	Megacolon, Aganglionic
Macrocolon	Hscr 1
Hirschsprung Disease Type 1	Hirschsprung Disease, Type 1
Congenital Dilatation Of Colon	Aganglionosis
Congenital Aganglionic Megacolon	Aganglionosis Of Colon
Bowel Aganglionosis	Colon Aganglionosis
Hirschsprung Megacolon

Mitochondrial Complex I Deficiency, Nuclear Type 1

Mitochondrial Complex I Deficiency	Nadh:Q(1) Oxidoreductase Deficiency
MC1DN1	Nadh-Coenzyme Q Reductase Deficiency
Isolated Mitochondrial Respiratory Chain Complex I Deficiency	Isolated Nadh-Coenzyme Q Reductase Deficiency
Isolated Nadh-Coq Reductase Deficiency	Isolated Nadh-Ubiquinone Reductase Deficiency
Mitochondrial Nadh Dehydrogenase Component Of Complex I, Deficiency Of	Nuclear Type Mitochondrial Complex I Deficiency 1
Isolated Complex I Deficiency	Complex 1 Mitochondrial Respiratory Chain Deficiency
Nadh Coenzyme Q Reductase Deficiency	Complex I Mitochondrial Respiratory Chain Deficiency
Deficiency Of Mitochondrial Nadh Dehydrogenase Component Of Complex I	Nadh:Ubiquinone Oxidoreductase Deficiency
Complex I, Mitochondrial Respiratory Chain, Deficiency Of

Related Agents

Approval

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-N0394	L-Cystine		≥98.0%	Unkown
HY-107916	Thyrotropin		/	Unkown
HY-B0976	Fenoterol	Agonist	99.08%	Unkown
HY-B0976A	Fenoterol hydrobromide	Agonist	99.90%	Unkown
HY-109520	Glatiramer acetate		≥98.0%	Unkown
HY-17002	Suplatast (Tosilate)	Inhibitor	98.33%	Unkown
HY-B0976AR	Fenoterol hydrobromide (Standard)	Agonist	/	Unkown

Inhibitory Antibodies (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P99025	Lebrikizumab	Inhibitor	99.90%	Unkown
HY-P99396	Spesolimab	Inhibitor	99.10%	Unkown
HY-P99256	Tildrakizumab	Antagonist	95.00%	Unkown

Clinical Phase

Bioactive Molecules (13)

Cat. No.	Product Name	Effect	Purity	Phase
HY-101092	QS-21	Activator	99.67%	Phase 3
HY-10535	Evofosfamide	Inducer	≥98.0%	Phase 3
HY-148074	Zelnecirnon	Inhibitor	99.84%	Phase 2
HY-124573	OBI-3424		99.23%	Phase 2
HY-15342	Timapiprant	Antagonist	99.48%	Phase 2
HY-118250	GSK2245035		99.85%	Phase 2
HY-17632	Tarloxotinib bromide	Inhibitor	99.26%	Phase 2
HY-15342A	Timapiprant sodium	Inhibitor	99.61%	Phase 2
HY-114141	BI-671800	Antagonist	99.36%	Phase 2
HY-103637A	Vimirogant hydrochloride	Inhibitor	98.39%	Phase 2
HY-12284	NVP-QAV680	Antagonist	/	Phase 2
HY-103637	Vimirogant	Inhibitor	/	Phase 2
HY-150298	Soquelitinib	Inhibitor	99.71%	Phase 1

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P990090	Rademikibart	Inhibitor	/	Phase 3

Pre-clinical Phase

Bioactive Molecules (127)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-153808	Complete Freund's adjuvant (CFA)		/	Unkown
HY-15826	SGC-CBP30	Inhibitor	99.83%	Unkown
HY-125801	3-Oxo-5β-cholanoic acid	Inhibitor	99.37%	Unkown
HY-116961	TH1020		99.60%	Unkown
HY-12776	GSK805	Inhibitor	98.01%	Unkown
HY-126360	Oxazolone		≥98.0%	Unkown
HY-125276	TH5487	Inhibitor	98.76%	Unkown
HY-123604	TH1834		99.60%	Unkown
HY-147313	TH10785	Activator	99.93%	Unkown
HY-134771	YM-341619	Inhibitor	99.06%	Unkown
HY-106224B	Orexin A (human, rat, mouse) (acetate)	Agonist	99.93%	Unkown
HY-111818	TH34	Inhibitor	99.52%	Unkown
HY-N2279	Kurarinone		99.47%	Unkown
HY-108522	PA452	Antagonist	≥99.0%	Unkown
HY-122818	bpV(phen) trihydrate		≥98.0%	Unkown
HY-12814	TH588	Inhibitor	99.20%	Unkown
HY-123604A	TH1834 dihydrochloride		99.68%	Unkown
HY-122630	TH-257	Inhibitor	98.01%	Unkown
HY-W011220	Ciglitazone	Agonist	98.89%	Unkown
HY-16965	TH287	Inhibitor	98.29%	Unkown
HY-P3993A	(Gly14)-Humanin (human) (acetate)	Inhibitor	99.86%	Unkown
HY-155950	TH9619		99.33%	Unkown
HY-101392	Harmane	Inhibitor	99.91%	Unkown
HY-120000	MS402	Inhibitor	99.62%	Unkown
HY-N0592A	Demethyleneberberine chloride		98.93%	Unkown
HY-N4084	Thonningianin A	Inducer	99.73%	Unkown
HY-150168	TH-Z145	Inhibitor	95.50%	Unkown
HY-125209	TH5427		99.92%	Unkown
HY-P1907	Human Papillomavirus (HPV) E7 protein (49-57)		98.92%	Unkown
HY-138113	Pyrrothiogatain		96.77%	Unkown
HY-145848	ERRγ agonist-1	Agonist	98.70%	Unkown
HY-150167	TH-Z93	Inhibitor	99.00%	Unkown
HY-135909	TH1217	Modulator	99.73%	Unkown
HY-139780	JNJ-61803534	Inhibitor	99.88%	Unkown
HY-144200	CCR8 antagonist 2	Antagonist	99.71%	Unkown
HY-W677684	Nurr1 agonist 2	Agonist	99.27%	Unkown
HY-153808B	Complete Freund's adjuvant (CFA, 1 mg/ml)		/	Unkown
HY-N6636	Valencene	Inhibitor	≥70.0%	Unkown
HY-P1252	Parathyroid Hormone (1-34), bovine	Agonist	99.04%	Unkown
HY-W010520	Methylisothiazolinone		99.37%	Unkown
HY-123468	HA-1004	Inhibitor	99.03%	Unkown
HY-125390	SM-360320	Agonist	98.07%	Unkown
HY-151539	TH470	Inhibitor	99.57%	Unkown
HY-161296	TH6342	Inhibitor	98.90%	Unkown
HY-16668	Tyrphostin A1	Inhibitor	98.96%	Unkown
HY-142938	RORγt agonist 3	Agonist	98.12%	Unkown
HY-120574	TH1338	Inhibitor	98.77%	Unkown
HY-120785	SR1555	Antagonist	99.69%	Unkown
HY-136065	bpV(phen)		≥98.0%	Unkown
HY-N0592	Demethyleneberberine		≥98.0%	Unkown
HY-113238F	FITC-Lithocholic acid 3-sulfate		90.01%	Unkown
HY-B0976AS	Fenoterol-d6 hydrobromide	Agonist	95.32%	Unkown
HY-138115	7ß,27-Dihydroxycholesterol	Activator	≥99.0%	Unkown
HY-145809	FASN-IN-5	Inhibitor	99.81%	Unkown
HY-146243	TH-Z835		/	Unkown
HY-158694A	TLR7 agonist 20 hydrochloride	Agonist	99.86%	Unkown
HY-159102	PVP-037.2	Agonist	/	Unkown
HY-N10534	Lewis X trisaccharide	Inhibitor	≥99.0%	Unkown
HY-N7501	Isoformononetin	Inhibitor	99.60%	Unkown
HY-P5333A	Aβ1-14-εK-KKK-MvF5 Th acetate	Inhibitor	99.93%	Unkown
HY-W002291	p-Fluoro-L-phenylalanine		99.91%	Unkown
HY-128353	ROR agonist-1	Antagonist	/	Unkown
HY-159507	Brezivaptan		/	Unkown
HY-125209A	TH5427 hydrochloride	Inhibitor	/	Unkown
HY-126252	A-9758	Inhibitor	/	Unkown
HY-130243	RORγt Inverse agonist 6	Antagonist	98.97%	Unkown
HY-142806	RORγt inverse agonist 26		/	Unkown
HY-160040A	Cobitolimod sodium	Agonist	/	Unkown
HY-101871	Trehalose 6-behenate		/	Unkown
HY-110295	SPL-334	Inhibitor	/	Unkown
HY-112348	HA-1004 hydrochloride	Inhibitor	/	Unkown
HY-116890	CRTh2 antagonist 4		/	Unkown
HY-118250A	GSK2245035 maleate		/	Unkown
HY-120225	NJK14047	Inhibitor	/	Unkown
HY-120785A	SR1555 hydrochloride	Antagonist	/	Unkown
HY-125693	L685818	Inhibitor	/	Unkown
HY-126037	(±)-ML 209	Antagonist	99.87%	Unkown
HY-132828	Odatroltide	Inhibitor	/	Unkown
HY-132851	Corixetan		/	Unkown
HY-135773	CRTh2 antagonist 3		/	Unkown
HY-135843	TH-263		/	Unkown
HY-137292	PTB7-Th		/	Unkown
HY-139193	TH1760		/	Unkown
HY-142703	RORγt inverse agonist 28	Inhibitor	/	Unkown
HY-142937	RORγt agonist 2	Agonist	/	Unkown
HY-143885	JAK1/TYK2-IN-3	Inhibitor	/	Unkown
HY-145491	Resolvin D5		/	Unkown
HY-145577	Lafadofensine		/	Unkown
HY-149029	TH-6		95.00%	Unkown
HY-153662	TH-Z816	Inhibitor	/	Unkown
HY-153663	TH-Z827	Inhibitor	/	Unkown
HY-155219	TH9028	Inhibitor	/	Unkown
HY-155487	JTE-151	Inhibitor	/	Unkown
HY-155505	AHR agonist 4	Agonist	/	Unkown
HY-155680	BET BD2-IN-1	Inhibitor	/	Unkown
HY-157020	UniPR1449	Antagonist	/	Unkown
HY-158694	TLR7 agonist 20	Agonist	/	Unkown
HY-160040	Cobitolimod	Agonist	/	Unkown
HY-161255	3,4-DAA	Inhibitor	/	Unkown
HY-162490	TF-S14	Inhibitor	/	Unkown
HY-162727	GCS-12		/	Unkown
HY-163704	KRN7000 analog 1		/	Unkown
HY-163801	Nurr1 agonist 9	Agonist	/	Unkown
HY-164454	AJI-100	Inhibitor	/	Unkown
HY-164455	AJI-214	Inhibitor	/	Unkown
HY-167692	JI069		/	Unkown
HY-N0976	1,11b-Dihydro-11b-hydroxymedicarpin		/	Unkown
HY-N6636R	Valencene (Standard)	Inhibitor	/	Unkown
HY-N7501S	Isoformononetin-d3		98.64%	Unkown
HY-N7512	Asimilobine		/	Unkown
HY-P1052	Myelin Basic Protein(87-99)		/	Unkown
HY-P1252A	Parathyroid Hormone (1-34), bovine TFA	Agonist	/	Unkown
HY-P3993	(Gly14)-Humanin (human)	Inhibitor	/	Unkown
HY-P4790	Acetyl-Exenatide	Inhibitor	/	Unkown
HY-RS14467	TH Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-W010520R	Methylisothiazolinone (Standard)		/	Unkown
HY-W018829	10-Undecenal		97.96%	Unkown
HY-112863	RORγt inhibitor 3	Inhibitor	/	Unkown
HY-118428	Fluenetil		/	Unkown
HY-122349	Lotrifen		/	Unkown
HY-123568	PBI-1393		/	Unkown
HY-12814A	TH588 hydrochloride	Inhibitor	/	Unkown
HY-138143	N-(p-Tosyl)-GPR-pNA acetate		/	Unkown
HY-16965A	TH287 hydrochloride	Inhibitor	/	Unkown
HY-N3548	Catalpalactone	Inhibitor	/	Unkown
HY-P10463	ssK36	Inhibitor	/	Unkown
HY-11054	TH-237A		98.55%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	TH	VGNC	VGNC:66147
Rattus norvegicus	TH	RGD	RGD:3853
Bos taurus	TH	VGNC	VGNC:35816
Canis familiaris	TH	VGNC	VGNC:47322
Mus musculus	TH	MGD	MGI:98735
Macaca mulatta	TH	VGNC	VGNC:78342
Macaca fascicularis	TH	NCBI	NCBI:102134074
Canis lupus familiaris	TH	NCBI
Susscrofa domestica	TH	NCBI
Leporidae	TH	NCBI
Others	TH	NCBI