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Results for "

AMC

" in MedChemExpress (MCE) Product Catalog:

122

Inhibitors & Agonists

28

Fluorescent Dye

1

Biochemical Assay Reagents

115

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0027

    Coumarin 120; AMC

    Fluorescent Dye Antibiotic Fungal Infection
    7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively.
    7-Amino-4-methylcoumarin
  • HY-114568

    Eukaryotic Initiation Factor (eIF) Apoptosis Inflammation/Immunology
    AMC-01 is a potent chemical probe that regulates eIF2-α activity. AMC-01 induces protein kinase RNA activation (PKR) kinase and nuclear factor κb (NF-κB). AMC-01 inhibits apoptosis .
    AMC-01
  • HY-P2237

    Amino Acid Derivatives Endocrinology
    Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic assays .
    Boc-Leu-Gly-Arg-AMC
  • HY-P1003
    Ac-DEVD-AMC
    4 Publications Verification

    Fluorescent Dye Others
    Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
    Ac-DEVD-AMC
  • HY-P3363

    Caspase Cancer
    Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .
    Z-DEVD-AMC
  • HY-28325

    Reactive Oxygen Species p38 MAPK Cancer
    AMC-04 is an unfolded protein response (UPR) activator, which activates UPR pathway through ROS and p38 MAPK signaling and induces apoptotic cell death. AMC-04 can be used for cancer research .
    AMC-04
  • HY-143285

    Fluorescent Dye Infection
    AMC-GlcNAc (compound 1) is a potent fluorogenic probe for detection and characterization of β-hexosaminidase enzyme activity. AMC-GlcNAc enables continuous monitoring by turn-on fluorescence and fluorescence signal is constant over a wide pH range (Ex=325 nm, Em=390 nm). AMC-GlcNAc enables ratiometric fluorescence detection with high sensitivity and low background, which can be used to screen for recombinant dispersin B activity in E. coli cell lysate .
    AMC-GlcNAc
  • HY-120957

    AMC-AA; 7-Amino-4-methyl coumarin-arachidonamide

    Endogenous Metabolite Metabolic Disease
    AMC arachidonoyl amide (AMC-AA) is one of several fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.1 FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its nominal endogenous substrate anandamide.2 Exposure of AMC-AA to FAAH activity results in the release of the fluorescent aminomethyl coumarin that absorbs at 360 nm and emits at 465 nm. This allows the fast and convenient measurement of FAAH activity using a simple cuvette or microplate fluorometer.
    AMC Arachidonoyl Amide
  • HY-D0002

    Coumarin 120 hydrogensulfate; AMC hydrogensulfate

    Fluorescent Dye Others
    7-Amino-4-methylcoumarin hydrogensulfate (Coumarin 120 hydrogensulfate; AMC hydrogensulfate) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    7-Amino-4-methylcoumarin hydrogensulfate
  • HY-P10317

    Fluorescent Dye Others
    Suc-YVAD-AMC is used to measure the cysteine proteins of the proteasome.Suc-YVAD-AMC releases fluorescent AMC when cleaved by cysteine proteases to assess the enzymatic activity of the proteasome .
    Suc-YVAD-AMC
  • HY-P1759

    Z-FR-AMC

    Cathepsin Others
    N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes .
    N-CBZ-Phe-Arg-AMC
  • HY-135070

    Ac-Arg-Leu-Arg-AMC

    Proteasome Others
    Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes .
    Ac-RLR-AMC
  • HY-W753820A

    Boc-Leu-Arg-Arg-AMC TFA

    Biochemical Assay Reagents Others
    Boc-LRR-AMC TFA (Boc-Leu-Arg-Arg-AMC TFA) is the TFA salt form of Boc-LRR-AMC (HY-115391). Boc-LRR-AMC TFA is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
    Boc-LRR-AMC TFA
  • HY-P2008
    Boc-Ile-Glu-Gly-Arg-AMC
    1 Publications Verification

    IEGR-AMC

    Factor Xa Cardiovascular Disease
    Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) is an activated factor X (FXa) specific fluorogenic peptide substrate used for Factor VIII determination .
    Boc-Ile-Glu-Gly-Arg-AMC
  • HY-P2717

    Caspase Infection
    Ac-YVAD-AMC is an inhibitor for caspase. Ac-YVAD-AMC inhibits bacteria-induced cell death of hypersensitive response (HR) cells .
    Ac-YVAD-AMC
  • HY-115391

    Boc-Leu-Arg-Arg-AMC

    Biochemical Assay Reagents Others
    Boc-LRR-AMC (Boc-Leu-Arg-Arg-AMC) is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
    Boc-LRR-AMC
  • HY-135070B

    Ac-Arg-Leu-Arg-AMC TFA

    Proteasome Others
    Ac-RLR-AMC (Ac-Arg-Leu-Arg-AMC) TFA is a fluorogenic substrate for the 26S proteasome (Ex/Em: 380/440-460 nm). AMC is released upon cleavage, and its fluorescence can be used to quantify the trypsin-like activity of 26S proteasomes .
    Ac-RLR-AMC TFA
  • HY-P10082

    Caspase Others
    Ac-VETD-AMC is a synthetic peptide substrate for caspase 8. Ac-VETD-AMC also has potential to assess functional activity of recombinant phytaspase .
    Ac-VETD-AMC
  • HY-137164A

    Fluorescent Dye Others
    Ala-Ala-Phe-AMC TFA is the TFA salt form for Ala-Ala-Phe-AMC. Ala-Ala-Phe-AMC TFA is a fluorogenic substrate, which is used to for tripeptidyl peptidase II (TPPII) activity determination .
    Ala-Ala-Phe-AMC TFA
  • HY-D1634A

    Cathepsin Others
    Bz-FVR-AMC TFA is a fluorogenic substrate for procathepsin with a kcat/Km value of 1070 mM -1s -1. The high concentration of BZ-FVR-AMC inhibits the substrate .
    Bz-FVR-AMC TFA
  • HY-W927376

    Fluorescent Dye Others
    Boc-Val-Arg-AMC is a synthetic peptide compound. As a specific fluorescent substrate, Boc-Val-Arg-AMC can be specifically cleaved by specific enzymes, especially thrombin, to release a fluorescent molecule AMC (7-amino-4-methylcoumarin), which can be used to monitor thrombin activity. Boc-Val-Arg-AMC can be used to detect thrombin activity in plasma samples .
    Boc-Val-Arg-AMC
  • HY-P10240

    Fluorescent Dye Others
    Ac-WVAD-AMC is a fluorogenic substrate for caspase 1 .
    Ac-WVAD-AMC
  • HY-P4217

    Cathepsin Others
    Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity .
    Z-Gly-Pro-Arg-AMC hydrochloride
  • HY-134434

    Cathepsin Others
    Z-Arg-Arg-AMC hydrochloride is a selective substrate of cathepsin B .
    Z-Arg-Arg-AMC hydrochloride
  • HY-129867

    Z-LLL-AMC

    Proteasome Others
    Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome .
    Z-Leu-Leu-Leu-AMC
  • HY-137199

    Biochemical Assay Reagents Others
    Pro-Phe-Arg-AMC is a synthetic peptide substrate of Cysteine peptidases (CPs) .
    Pro-Phe-Arg-AMC
  • HY-P3364

    Sirtuin Others
    Ac-QPKK(Ac)-AMC is a fluorogenic substrate for sirtuin through sirtuin deacetylation .
    Ac-QPKK(Ac)-AMC
  • HY-134961

    Fluorogenic Proteasome Substrate; Z-ARR-AMC

    Proteasome Others
    Z-Ala-Arg-Arg-AMC (Fluorogenic Proteasome Substrate) is a fluorogenic substrate for assaying trypsin-like activity of proteasome .
    Z-Ala-Arg-Arg-AMC
  • HY-P10060

    Biochemical Assay Reagents Others
    Boc-Val-Gly-Arg-AMC is a peptide substrate that can be used to study activity of the proteasome .
    Boc-Val-Gly-Arg-AMC
  • HY-P0019A
    Z-Gly-Gly-Arg-AMC acetate
    Maximum Cited Publications
    9 Publications Verification

    Fluorescent Dye Others
    Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).
    Z-Gly-Gly-Arg-AMC acetate
  • HY-P5976

    Renin Substrate I

    Renin Others
    Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-AMC (Renin Substrate I) is a renin substrate
    Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-AMC
  • HY-137844

    Leu-AMC hydrochloride

    Fluorescent Dye Others
    L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro .
    L-Leucine-7-amido-4-methylcoumarin hydrochloride
  • HY-P2176

    Z-Leu-Arg-Gly-Gly-AMC

    Biochemical Assay Reagents Others
    Z-LRGG-AMC (Z-Leu-Arg-Gly-Gly-AMC) is a fluorescent substrate that hydrolyzes and releases free fluorescent 7-amino-4-methylcoumarin (AMC). Detection wavelength of AMC: Ex/Em=360/460 nm .
    Z-LRGG-AMC
  • HY-P4417

    Fluorescent Dye Others
    Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .
    Ac-IEPD-AMC
  • HY-P4340A

    Cathepsin Others
    Arg-Arg-AMC acetate is the acetate salt form of Arg-Arg-AMC (HY-P4340). Arg-Arg-AMC acetate is a fluorescent substrate for cathepsin B and used in the cathepsin B activity assay .
    Arg-Arg-AMC acetate
  • HY-P10142

    Fluorescent Dye Others
    Ac-YEVD-AMC is a fluorescent substrate of caspase-1/11. Ac-YEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection when treating with cell lysate .
    Ac-YEVD-AMC
  • HY-136626
    Z-Ala-Ala-Asn-AMC
    3 Publications Verification

    Cbz-Ala-Ala-Asn-AMC

    Fluorescent Dye Cancer
    Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC .
    Z-Ala-Ala-Asn-AMC
  • HY-P4547

    AC-WEHD-AMC

    Caspase Others
    Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) is a potent fluorogenic substrate of caspase-1 .
    Ac-Trp-Glu-His-Asp-AMC
  • HY-P4548

    Boc-RVRR-AMC

    Furin Others
    Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin .
    Boc-Arg-Val-Arg-Arg-AMC hydrochloride
  • HY-P4449

    Caspase Cancer
    Ac-VRPR-AMC is a fluorogenic metacaspase substrate. Ac-VRPR-AMC can be used to tests metacaspase activity .
    Ac-VRPR-AMC
  • HY-P4417A

    Fluorescent Dye Others
    Ac-IEPD-AMC TFA is a fluorescent substrate used to measure protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC fluoresces under UV light irradiation and can emit fluorescent signals .
    Ac-IEPD-AMC TFA
  • HY-P4427

    Fluorescent Dye Others
    Z-VAN-AMC is a fluorogenic substrate. Z-VAN-AMC can be hydrolysed by a phytophagous mite of legumain-like activity .
    Z-VAN-AMC
  • HY-P3110

    Fluorescent Dye Others
    Ac-WLA-AMC is a fluorogenic substrate of caspase-3. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity .
    Ac-DNLD-AMC
  • HY-D1652

    Caspase Others
    Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity .
    Ac-LEHD-AMC
  • HY-P10147

    Caspase Cancer
    Ac-LDESD-AMC is a caspase-2 inhibitor. Ac-LDESD-AMC has a peptide sequence of Leu-Asp-Glu-Ser-Asp .
    Ac-LDESD-AMC
  • HY-P1759B

    Z-FR-AMC TFA

    Cathepsin Others
    N-CBZ-Phe-Arg-AMC (Z-FR-AMC) TFA is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes .
    N-CBZ-Phe-Arg-AMC TFA
  • HY-120659

    Fluorescent Dye Others
    Gly-Gly-AMC is a fluorogenic peptide substrate. Gly-Gly-AMC can be used to assess bacterial protease activity of P. aeruginosa and S. aureus .
    Gly-Gly-AMC
  • HY-142021

    Parasite Infection
    Z-Leu-Arg-AMC is a 4-methylcoumarinyl-7-amide (Amc) leucine derivative with carboxybenzoyl (Z). Z-Leu-Arg-AMC is the active site of cysteine proteinase trypanopain-Tb from Trypanosoma brucei brucei .
    Z-Leu-Arg-AMC
  • HY-134435

    Fluorescent Dye Others
    Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm) .
    Z-Arg-AMC hydrochloride
  • HY-D1634

    Cathepsin Others
    Bz-FVR-AMC is a fluorogenic substrate for procathepsin with a kcat/Km value of 1070 mM -1s -1. The high concentration of BZ-FVR-AMC inhibits the substrate .
    Bz-FVR-AMC

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