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Results for "

5’-AMP

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (20) Cyclic GMP-AMP Synthase (13) Adenosine Deaminase (1) Adenosine Receptor (6) Adrenergic Receptor (4) Aminoacyl-tRNA Synthetase (1) Antibiotic (9) AP-1 (1) Apoptosis (7) ATP Synthase (1) Autophagy (4) Bacterial (31) Biochemical Assay Reagents (4) Calcium Channel (3) CaMK (2) CD73 (7) Checkpoint Kinase (Chk) (1) DNA/RNA Synthesis (3) Endogenous Metabolite (33) Endonuclease (1) ERK (3) FAK (1) FBPase (1) Fluorescent Dye (2) Fungal (7) GLP Receptor (1) Glucosidase (2) Glucosylceramide Synthase (GCS) (1) GLUT (1) HBV (1) HSP (2) HSV (1) IFNAR (2) iGluR (1) Influenza Virus (6) Insulin Receptor (1) IRAK (1) Isotope-Labeled Compounds (13) JNK (1) Keap1-Nrf2 (1) MAPKAPK2 (MK2) (1) MARCKS (1) mGluR (1) Mitochondrial Metabolism (1) NF-κB (2) Nucleoside Antimetabolite/Analog (2) Opioid Receptor (2) Organoid (1) Orthopoxvirus (2) Oxidative Phosphorylation (1) P2Y Receptor (5) Parasite (1) Phosphodiesterase (PDE) (19) PKA (20) PKC (3) PKG (1) Potassium Channel (2) PPAR (1) Prostaglandin Receptor (3) Ras (1) Reactive Oxygen Species (1) Somatostatin Receptor (2) STING (8) Taste Receptor (1) TGF-β Receptor (2) TNF Receptor (1) Toll-like Receptor (TLR) (1) Topoisomerase (1) Vasopressin Receptor (1) β-catenin (1)
By Research Areas:	Cancer (35) Cardiovascular Disease (16) Endocrinology (3) Infection (35) Inflammation/Immunology (41) Metabolic Disease (58) Neurological Disease (23)
Oligonucleotides:	Nucleotides and their Analogs (2)

206

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Targets Recommended: Cyclic GMP-AMP Synthase AMPK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W587488

Adenosine 3′-monophosphate 3′-AMP	Nucleoside Antimetabolite/Analog	Cancer
Adenosine 3′-monophosphate (3′-AMP), a nucleotide, is a cyclic AMP production agonist .

HY-114615

AMP-Deoxynojirimycin AMP-DNM	Glucosidase Glucosylceramide Synthase (GCS)	Neurological Disease
AMP-Deoxynojirimycin (AMP-DNM) is a potent ceramide glucosyltransferase and GCase 2 inhibitor. AMP-Deoxynojirimycin also is a GlcCer biosynthesis inhibitor .

HY-134332

8-pCPT-5'-AMP 8-(4-Chlorophenylthio)-5'-AMP	PKA PKG	Others
8-pCPT-5'-AMP is an analogue of 5'-AMP and a lipophilic activator of PKA, PKG and Epac (exchange protein activated by cAMP) .

HY-131773

2-Cl-5'-AMP	Others	Others
2-Cl-5'-AMP is a 5'-AMP analogue and can be used for receptor mapping research .

HY-15073

Becampanel AMP 397	iGluR	Neurological Disease
Becampanel (AMP397) is the first competitive AMPA antagonist and an antiepileptic agent.

HY-19310

AMP-579	Adenosine Receptor	Cardiovascular Disease Metabolic Disease
AMP-579 is an adenosine receptor agonist that primarily targets adenosine A1 and A2_A receptors (with K_i values of 1.7 and 4.5 nM for the A1 receptor in rat brain and adipocytes, and a K_i value of 56 nM for the A2_A receptor in rat brain). AMP-579 inhibits lipolysis, restores insulin-dependent glucose transport, and reduces heart rate through the activation of A1 receptors, while it induces vasodilation, particularly in coronary arteries, through the activation of A2_A receptors (with an IC₅₀ of 0.3 μM in porcine coronary arterial rings). AMP 579 shows potential for application in cardioprotection and the treatment of acute myocardial infarction .

HY-106723

AMP-PCP	HSP	Cancer
AMP-PCP is an ATP analogue and can bind to Hsp90 N-terminal domain with a K_d value of 3.8 μM. AMP-PCP binding favors the formation of the active homodimer of Hsp90 .

HY-117543

Ethonafide AMP-53; 6-Ethoxyazonafide	Topoisomerase	Cancer
Ethonafide (AMP-53) is an anthracene-containing derivative of Amonafide that belongs to the Azonafide series of anticancer agents. Ethonafide (AMP-53) inhibits topoisomerase II activity by stabilizing the enzyme-DNA complex, involving both topoisomerase IIα and β .

HY-P3417

Amp1EP9	Bacterial	Infection
Amp1EP9 is an antimicrobial peptide. Amp1EP9 is a powerful tool for developing potent and nontoxic antimicrobial agents. Amp1EP9 has the potential for the research of multidrug-resistant bacterial infections .

HY-103064

*2-Methylthio-AMP* sodium**	P2Y Receptor	Cardiovascular Disease
2-Methylthio-AMP sodium is a selective and direct P2Y₁₂ antagonist. 2-Methylthio-AMP sodium is an inhibitor of ADP-dependent platelet aggregation .

HY-164556A

*3′-Deoxy-5′-AMP* sodium**	DNA/RNA Synthesis	Others
3′-Deoxy-5′-AMP sodiumIt can be used to study various physiological processes such as energy metabolism and information transmission.

HY-106723A

AMP-PCP disodium	HSP	Cancer
AMP-PCP disodium is an ATP analogue and can bind to Hsp90 N-terminal domain with a K_d value of 3.8 μM. AMP-PCP disodium binding favors the formation of the active homodimer of Hsp90 .

HY-W802013

DOTA-4AMP	Biochemical Assay Reagents	Others
DOTA-4AMPis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-4AMP can be used for conjugation of peptides and radionuclides.

HY-137721

Cyclic tri-AMP	Endonuclease	Infection
Cyclic tri-AMP is a component of the cyclic oligonucleotide-based anti-phage signaling system (CBASS), and acts as the second messenger in the immune response against viral infection. Cyclic tri-AMP binds to and activates DNA endonuclease NucC, results in cell death and exhibits antiviral activity .

HY-12326

c-di-AMP Cyclic diadenylate; Cyclic-di-AMP	STING Bacterial Endogenous Metabolite	Inflammation/Immunology
c-di-AMP (Cyclic diadenylate) is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP (Cyclic diadenylate) is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP (Cyclic diadenylate) acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .

HY-130777

AMP-PNP Adenylyl imidodiphosphate	Biochemical Assay Reagents	Others
AMP-PNP (Adenylyl imidodiphosphate) is a non-hydrolysable ATP analogue .

HY-B1511A

*Cyclic AMP* sodium** 5+ Cited Publications Cyclic adenosine monophosphate sodium; Adenosine cyclic 3', 5'-monophosphate sodium; cAMP sodium; Cyclic AMP sodium	Biochemical Assay Reagents	Neurological Disease Metabolic Disease Cancer
Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes .

HY-160199

3'-L-Histidyl-AMP	Others	Others
3'-L-Histidyl-AMP is applicable for nucleoside modification (DNA, RNA) .

HY-12326A

*c-di-AMP* disodium** 2 Publications Verification Cyclic diadenylate disodium; Cyclic-di-AMP disodium	STING Bacterial Endogenous Metabolite	Inflammation/Immunology
c-di-AMP (Cyclic diadenylate) sodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP sodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP sodium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .

HY-12326B

*c-di-AMP* diammonium** 2 Publications Verification Cyclic diadenylate diammonium; Cyclic-di-AMP diammonium	STING Bacterial Endogenous Metabolite	Inflammation/Immunology
c-di-AMP diammonium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP diammonium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP diammonium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .

HY-145652

Narmafotinib AMP-945	FAK	Cancer
Narmafotinib (AMP-945) is an inhibitor of the enzyme focal adhesion kinase (FAK, K_D=0.21 nM). Narmafotinib inhibits autophosphorylation of 397Y-FAK in MDA-MB-231 cells with an IC₅₀=7 nM and exhibits low general cellular toxicity (IC₅₀=2.7 μM, MDA-MB-231 cells) .

HY-124151

Adenosine-2'-monophosphate 2'-AMP; Adenosine 2'-phosphate; AMP 2'-phosphate	Adenosine Receptor Endogenous Metabolite	Neurological Disease
Adenosine-2'-monophosphate (2'-AMP) is converted by extracellular 2’,3'-CAMP. Adenosine-2'-monophosphate is further metabolized to extracellular adenosine (a mechanism called the extracellular 2’,3’-cAMP-adenosine pathway). Adenosine-2'-monophosphate inhibits LPS-induced TNF-α and CXCL10 production via A_2A receptor activation .

HY-160199A

*3'-L-histidyl-AMP* disodium**	Others	Others
3'-L-histidyl-AMP (disodium) is applicable for nucleoside modification (DNA, RNA) .

HY-131844

6-Bnz-5'-AMP N6-Benzoyladenosine-5'-O-monophosphate	Others	Others
6-Bnz-5'-AMP is a lipophilic analogue of adenosine-5'-O-monophosphate and a potential metabolite of N ⁶-Benzoyl-cAMP. 6-Bnz-5'-AMP exhibits some cytokinin activity in tobacco and soybean tissue culture assays .

HY-111673

*8-CPT-Cyclic AMP* sodium** 8-CPT-cAMP sodium; 8-(p-Chlorophenylthio)-cAMP sodium	PKA Phosphodiesterase (PDE)	Inflammation/Immunology
8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of *cyclic AMP-dependent protein kinase (PKA). 8-CPT-Cyclic AMP* sodium is also a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC₅₀ of 0.9 μM. 8-CPT-Cyclic AMP sodium also inhibits PDE III and PDE IV with IC₅₀AMP sodium is a very high affinity for Epac and is a potent Epac activator .

HY-128933

AMP-PNP tetralithium 1 Publications Verification Adenylyl-imidodiphosphate tetralithium	Potassium Channel	Metabolic Disease
AMP-PNP tetralithium (Adenylyl-imidodiphosphate tetralithium) is a non-hydrolysable analogue of ATP and inhibits K_ATP channels .

HY-B1511R

*Cyclic AMP* (Standard)** Cyclic adenosine monophosphate (Standard); Adenosine cyclic 3', 5'-monophosphate (Standard); cAMP (Standard)	Endogenous Metabolite	Cancer
Cyclic AMP (Standard) is the analytical standard of Cyclic AMP. Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .

HY-134266

8-Bromo-AMP 1 Publications Verification 8-Bromoadenosine 5'-monophosphate; 8-Bromoadenylic acid	Others	Cardiovascular Disease
8-Bromo-AMP (8-Bromoadenosine 5'-monophosphate) is a membrane permeable cAMP analogue. 8-Bromo-AMP can improve the ability of the heart to recover from ischemia and reperfusion by increasing the levels of ATP, ADP, and total adenine nucleotides .

HY-B1511

Cyclic AMP 5+ Cited Publications Cyclic adenosine monophosphate; Adenosine cyclic 3', 5'-monophosphate; cAMP	Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .

HY-134245

7-Deazaadenosine 5'-phosphate Tubercidin 5'-phosphate; 7-Deaza-AMP	Others	Others
7-Deazaadenosine 5'-phosphate (Tubercidin 5'-phosphate; 7-Deaza-AMP) is a potential substrate or competitive inhibitor of enzymes that interact with 5′-adenylic acid monophosphate. As a nucleotide derivative, 7-Deazaadenosine 5'-phosphate can regulate cellular functions by affecting intracellular signaling pathways, especially in signaling involving AMP .

HY-125989

2-Methylthio-AMP 1 Publications Verification 2-MeSAMP; 2-Methylthioadenosine 5′-monophosphate; 2-Methylthioadenosine 5′-phosphate	P2Y Receptor	Cardiovascular Disease
2-Methylthio-AMP (2-MeSAMP) is a selective and direct P2Y₁₂ antagonist. 2-Methylthio-AMP is an inhibitor of ADP-dependent platelet aggregation .

HY-B0277A

Vidarabine phosphate ara-AMP; ara-A 5'-monophosphate	HBV Antibiotic	Infection
Vidarabine phosphate (Ara-AMP), an antiviral agent, inhibits chronic HBV infection . Vidarabine phosphate also against herpes simplex and varicella zoster viruses .

HY-120993

1,N6-Ethenoadenosine 5'-monophosphate sodium 1,N6-Etheno-AMP sodium; 1,N6-ε-AMP sodium	Fluorescent Dye	Others
1,N6-Ethenoadenosine 5'-monophosphate (1,N6-Etheno-AMP) sodium is a highly fluorescent analog of adenosine 5'-monophosphate (AMP). 1,N6-Ethenoadenosine 5'-monophosphate sodium is a powerful probe for systems involving adenosine 5'-monophosphate and can be detected at low concentration. 1,N6-Ethenoadenosine 5'-monophosphate sodium has long wavelength of excitation (250-300 nm), and emission at 415 nm .

HY-131763

2'-O-MB-cAMP sodium 2'-O-Monobutyryl cyclic AMP sodium	Others	Others
2'-O-MB-cAMP (2'-O-Monobutyryl cyclic AM) sodium is an activatable proagent of Cyclic AMP (HY-B1511) .

HY-125989B

*2-Methylthio-AMP* diTEA** 2-MeSAMP diTEA; 2-Methylthioadenosine 5′-monophosphate diTEA; 2-Methylthioadenosine 5′-phosphate diTEA	P2Y Receptor	Cardiovascular Disease
2-Methylthio-AMP (2-MeSAMP) diTEA is a selective and direct P2Y₁₂ antagonist. 2-Methylthio-AMP diTEA is an inhibitor of ADP-dependent platelet aggregation .

HY-B1511S

*Cyclic AMP-13C5* Cyclic adenosine monophosphate-¹³C₅; Adenosine cyclic 3', 5'-monophosphate-¹³C₅; cAMP-¹³C₅	Isotope-Labeled Compounds	Others
Cyclic AMP- ¹³C₅ is a deuterated cyclic AMP.

HY-100564A

2',3'-cGAMP sodium 10+ Cited Publications 2'-3'-cyclic GMP-AMP sodium	Endogenous Metabolite STING IFNAR	Metabolic Disease
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm .

HY-100564

2',3'-cGAMP 10+ Cited Publications 2'-3'-cyclic GMP-AMP	Endogenous Metabolite STING IFNAR	Metabolic Disease
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm .

HY-A0181S2

Adenosine monophosphate-d12 dilithium AMP-d₁₂ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Others
Adenosine monophosphate-d₁₂ (AMP-d₁₂) dilithium is deuterium labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

HY-A0181S3

Adenosine monophosphate-13C10 dilithium AMP-¹³C₁₀ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Others
Adenosine monophosphate- ¹³C₁₀ (AMP- ¹³C₁₀) dilithium is ¹³C-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

HY-B0272S3

Rifampicin-d11 RifAMPin-d₁₁; Rifamycin AMP-d₁₁	Isotope-Labeled Compounds	Others
Rifampicin-d₁₁ (Rifampin-d₁₁; Rifamycin AMP-d₁₁)is the deuterium labeledRifampicin(HY-B0272) . Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. Rifampicin shows anti-orthopoxvirus activity .

HY-131810

5'-AMPS	Others	Others
5'-AMPS is an analogue of 5'-AMP and a substrate and competitive inhibitor or regulator of enzymes that interact with 5'-AMP .

HY-W011256

Adenosine 2',3'-cyclic phosphate sodium	Endogenous Metabolite	Metabolic Disease
Adenosine 2',3'-cyclic phosphate sodium is a 2',3'-cyclic purine nucleotide, which can be degrade to 2'-AMP and 3'-AMP .

HY-A0181S5

Adenosine monophosphate-15N5,d12 dilithium AMP-¹⁵N₅,d₁₂ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Others
Adenosine monophosphate- ¹⁵N₅,d₁₂ (AMP- ¹⁵N₅,d₁₂) dilithium is deuterium and ¹⁵N labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

HY-113401

Adenosine 2',3'-cyclic phosphate	Endogenous Metabolite	Metabolic Disease
Adenosine 2',3'-cyclic phosphate is a 2',3'-cyclic purine nucleotide. Adenosine 2',3'-cyclic phosphate can be degrade to 2'-AMP and 3'-AMP .

HY-A0181

Adenosine monophosphate 5+ Cited Publications AMP	Endogenous Metabolite	Others
Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

HY-120547

UCB-11056	Others	Neurological Disease Metabolic Disease
UCB-11056 is a modulator of *cyclic AMP* generation*. UCB-11056 can rapidly increase cyclic AMP* levels in the rat brain in vivo and potentiate stimulated cyclic AMP formation in vitro. UCB-11056 does not stimulate cAMP formation on its own. UCB-11056 is a potential nootropic drug .

HY-A0181S4

Adenosine monophosphate-13C10,15N5,d12 dilithium AMP-¹³C₁₀,¹⁵N₅,d₁₂ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Others
Adenosine monophosphate- ¹³C₁₀, ¹⁵N₅,d₁₂ (AMP- ¹³C₁₀, ¹⁵N₅,d₁₂) dilithium is ¹³C and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

HY-131846

6-Cl-5'-PuMP 6-Chloropurine 5'-ribonucleotide	Others	Others
6-Cl-5'-PuMP is a reactive analogue of adenosine 5’-O-monophosphate (5’-AMP), and is suitable for modifying position 6 using various nucleophiles .

HY-B0272

Rifampicin 20+ Cited Publications RifAMPin; Rifamycin AMP	Bacterial Influenza Virus Antibiotic Orthopoxvirus	Infection Cancer
Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. Rifampicin shows anti-orthopoxvirus activity.

Cat. No.	Product Name	Type

HY-P0136AF

FAM-SAMS TFA	Dyes
FAM-SAMS TFA is a 5-FAM (HY-66022) labeled SAMS (HY-P0136). SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK) .

HY-120993

1,N6-Ethenoadenosine 5'-monophosphate sodium

1,N6-Etheno-AMP sodium; 1,N6-ε-AMP sodium

Fluorescent Dyes/Probes

1,N6-Ethenoadenosine 5'-monophosphate (1,N6-Etheno-AMP) sodium is a highly fluorescent analog of adenosine 5'-monophosphate (AMP). 1,N6-Ethenoadenosine 5'-monophosphate sodium is a powerful probe for systems involving adenosine 5'-monophosphate and can be detected at low concentration. 1,N6-Ethenoadenosine 5'-monophosphate sodium has long wavelength of excitation (250-300 nm), and emission at 415 nm .

Cat. No.	Product Name	Type

HY-B1511A

*Cyclic AMP* sodium** Maximum Cited Publications 10 Publications Verification Cyclic adenosine monophosphate sodium; Adenosine cyclic 3', 5'-monophosphate sodium; cAMP sodium; Cyclic AMP sodium	Biochemical Assay Reagents
Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes .

HY-130777A

AMP-PNP lithium hydrate 1 Publications Verification Adenylyl imidodiphosphate lithium hydrate	Gene Sequencing and Synthesis
AMP-PNP lithium hydrate is a non-hydrolyzable analog of ATP. AMP-PNP can replace ATP for biological research and is not hydrolyzed by intracellular enzymes. In the study of BtuCD-F, a vitamin B12 transporter, it was found that AMP-PNP can block the channel formed by the two BtuCDs of the BtuCD-F complex, thereby preventing the entry of vitamin B12 .

HY-W010968

5'-Adenylic acid sodium hydrate 5+ Cited Publications A-5'-P sodium hydrate; AMP sodium hydrate; Adenosine 5'-monophosphate sodium hydrate	Biochemical Assay Reagents
5'-Adenylic acid (sodium hydrate) (A-5'-P (sodium hydrate); AMP (sodium hydrate); Adenosine 5'-monophosphate (sodium hydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .

HY-W802013

DOTA-4AMP	Chelators
DOTA-4AMPis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-4AMP can be used for conjugation of peptides and radionuclides.

HY-130777

AMP-PNP Adenylyl imidodiphosphate	Gene Sequencing and Synthesis
AMP-PNP (Adenylyl imidodiphosphate) is a non-hydrolysable ATP analogue .

HY-W010759

Inosine-5′-monophosphate disodium salt octahydrate	Gene Sequencing and Synthesis
Inosine-5'-monophosphate disodium salt octahydrate is a purine nucleotide that can be used as an umami tastant as well as a precursor of GMP and AMP .

Cat. No.	Product Name	Target	Research Area

HY-P0136

SAMS 2 Publications Verification	AMPK	Metabolic Disease
SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK).

HY-P5474

PMAP-23	Bacterial	Others
PMAP-23 is a biological active peptide. (an antimicrobial peptide (AMP) derived from porcine myeloid.)

HY-P3915

Esculentin 1A	Bacterial	Infection
Esculentin 1A is a frog skin-derived antimicrobial peptide (AMP) with potent in vitro anti-Pseudomonas activity .

HY-P3929A

PKI (14-24)amide TFA	PKA	Cancer
PKI (14-24)amide TFA is a potent PKA inhibitor. PKI (14-24)amide strongly inhibited cyclic AMP-dependent protein kinase activity in the cell homogenate .

HY-P0136AF

FAM-SAMS TFA	Fluorescent Dye	Others
FAM-SAMS TFA is a 5-FAM (HY-66022) labeled SAMS (HY-P0136). SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK) .

HY-P3417

Amp1EP9	Bacterial	Infection
Amp1EP9 is an antimicrobial peptide. Amp1EP9 is a powerful tool for developing potent and nontoxic antimicrobial agents. Amp1EP9 has the potential for the research of multidrug-resistant bacterial infections .

HY-P5468

NRC-16	Peptides	Others
NRC-16 is a biological active peptide. (pleurocidin-like cationic AMP)

HY-P3929

PKI (14-24)amide	PKA	Cancer
PKI (14-24)amide is a potent PKA inhibitor. PKI (14-24)amide strongly inhibited cyclic AMP-dependent protein kinase activity in the cell homogenate .

HY-P0136F

FAM-SAMS	Peptides	Others
FAM-SAMS is a 5-FAM (HY-66022) labeled SAMS (HY-P0136). SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK) .

HY-P4816

Pseudin-2	Bacterial Fungal	Infection Inflammation/Immunology
Pseudin-2, an AMP thast could be isolated from the skin of the South American paradoxical frog Pseudis paradoxa, exert a potent growth inhibitory effect against Gram-negative bacteria .

HY-P2148

P-113	Bacterial Antibiotic	Infection Inflammation/Immunology
P-113 is an antimicrobial peptide (AMP) derived from the human salivary protein histatin 5. P-113 is active against clinically important microorganisms such as Pseudomonas spp., Staphylococcus spp., and C. albicans .

HY-P3777

β-Bag cell peptide	Potassium Channel	Neurological Disease
β-Bag cell peptide is a neuroactive peptide. β-Bag cell peptide elevates cyclic AMP levels in the bag cell neurons. β-Bag cell peptide decreases the amplitudes of the voltage-dependent potassium currents .

HY-P4012

[Asu1,6-Arg8]Vasopressin	Vasopressin Receptor	Endocrinology
[Asu1,6-Arg8]Vasopressin is an vasopressin agonist which potentiates cyclic AMP accumulation and ACTH release induced by corticotropin-releasing factor (CRF) in rat anterior pituitary cells in culture .

HY-P3785

PKI(5-22)amide	PKA	Neurological Disease
PKI(5-22)amide is the active inhibitory fragment of the inhibitor of the *cyclic AMP-dependent protein kinase* (PKA). PKI(5-22)amide inhibits PKA activation, but fails to attenuate homologous desensitization of CRF1 receptors .

HY-P3899

[Nle8] Somatostatin (1-28)	Somatostatin Receptor	Metabolic Disease
[Nle8] Somatostatin (1-28) is a derivative of somatosttin (1-28) with norleucine replacing methionine in position 8. [Nle8] Somatostatin (1-28) increases the amylase release.[Nle8] Somatostatin (1-28) increases the cyclic AMP in pancreatic acini .

HY-163315

YPLP	Keap1-Nrf2 AMPK	Metabolic Disease
YPLP is a yeast-derived peptide Tyr-Pro-Leu-Pro, which exhibits activity in anti fatigue mechanisms through the nuclear factor erythroid-2-related factor 2 (Nrf2)- and AMP-activated protein kinase (AMPK) pathway. YPLP is orally active .

HY-P3899A

[Nle8] Somatostatin (1-28) (TFA)	Somatostatin Receptor	Metabolic Disease
[Nle8] Somatostatin (1-28) TFA is a derivative of somatosttin (1-28) with norleucine replacing methionine in position 8. [Nle8] Somatostatin (1-28) TFA increases the amylase release.[Nle8] Somatostatin (1-28) TFA increases the cyclic AMP in pancreatic acini .

HY-P2289

β-defesin 1 (pig) pBD-1	Bacterial	Infection
β-defesin 1 (pig) (pBD-1) is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites. β-defesin 1 (pig) has antimicrobial activities and contributes to mucosal and systemic host defenses in pigs .

HY-P1954

Epinecidin-1 Piscidin-1 (22-42)	Bacterial	Infection Cancer
Epinecidin-1 (Piscidin-1 (22-42)) is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). Epinecidin-1 has many functional usages including antibacterial, antifungal, antiviral, antiprotozoal, anticancer, immunomodulatory, and wound healing properties .

HY-P1954A

Epinecidin-1 TFA Piscidin-1 (22-42) TFA	Bacterial	Infection Cancer
Epinecidin-1 (Piscidin-1 (22-42)) TFA is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). Epinecidin-1 TFA has many functional usages including antibacterial, antifungal, antiviral, antiprotozoal, anticancer, immunomodulatory, and wound healing properties .

HY-126810A

NP213 TFA	Fungal	Infection
NP213 TFA is a rapidly acting, novel, first-in-class synthetic antimicrobial peptide (AMP), has anti-fungal activities. NP213 TFA targets the fungal cytoplasmic membrane and plays it role via membrane perturbation and disruption. NP213 TFA is effective and well-tolerated in resolving nail fungal infections .

HY-P2289A

β-defesin 1 (pig) (TFA) pBD-1 TFA	Bacterial	Infection
β-defesin 1 (pig) (pBD-1) TFA is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites. β-defesin 1 (pig) TFA has antimicrobial activities and contributes to mucosal and systemic host defenses in pigs .

HY-P1978

CysHHC10	Bacterial	Infection
CysHHC10 is a synthetic antimicrobial peptide (AMP), and exhibits strong anti-microbial properties against both Gram-positive and Gram-negative bacteria. The MIC values of CysHHC10 against *E. coli, P. aeruginosa, S. aureus* and *S. epidermidis* are 10.1 mM, 20.2 mM, 2.5 mM and 1.3 mM, respectively .

HY-P5680

SpHistin	Bacterial	Inflammation/Immunology
SpHistin is an antimicrobial peptide (AMP). SpHistin can bind to LPS (HY-D1056) and permeabilize the bacterial membrane. SpHistin combined with Rifampicin (HY-B0272) and Azithromycin (HY-17506) promotes the intracellular uptake of the antibiotics and subsequently enhances the bactericidal activity of both agents against P. aeruginosa .

HY-P10602

PKA Regulatory Subunit II Substrate RII phosphopeptide	Peptides	Others
PKA Regulatory Subunit II Substrate (RII phosphopeptide) is a tool peptide derived from the regulatory subunit Type II (RII) of cyclic AMP-dependent protein kinase (PKA). PKA Regulatory Subunit II Substrate is commonly used to mimic the phosphorylation of protein kinases and as a specific substrate for protein phosphatases to assess the activities of these enzymes .

HY-P2048A

MOTS-c(human) acetate	AMPK GLUT	Metabolic Disease
MOTS-c(human) acetate is a mitochondrial-derived peptide. MOTS-c(human) acetate induces the accumulation of AMP analog AICAR, increases activation of AMPK and expression of its downstream GLUT4. MOTS-c(human) acetate induces glucose uptake and improves insulin sensitivity. MOTS-c(human) acetate has implications in the regulation of obesity, diabetes, exercise, and longevity .

HY-P1978A

CysHHC10 TFA	Bacterial	Infection
CysHHC10 TFA is a synthetic antimicrobial peptide (AMP), and exhibits strong anti-microbial properties against both Gram-positive and Gram-negative bacteria. The MIC values of CysHHC10 TFA against *E. coli, P. aeruginosa, S. aureus* and *S. epidermidis* are 10.1 mM, 20.2 mM, 2.5 mM and 1.3 mM, respectively .

HY-P5435

LKBtide	Peptides	Others
LKBtide is a biological active peptide. (This is a peptide substrate that is phosphorylated by Serine/Threonine kinase 11 (STK11), also known as LKB1. LKBtide is derived from sucrose non-fermenting 1 (SNF1) protein kinase, which is normally activated by the LKB1/AMP-activated protein kinase (AMPK) signaling pathway.)

HY-P10367

Ziptide	MAPKAPK2 (MK2) Checkpoint Kinase (Chk) AMPK	Others
Ziptide is a substrate for MAPK activated protein kinase 2 (MAPKAPK2, K_m = 5 μM), MAPKAPK3 (K_m = 30 μM), PARK (K_m = 40 μM), checkpoint kinase 1 (Chk1, K_m = 5 μM), AMP-activated protein kinase (AMPK, K_m = 75 μM), and calcium/calmodulin-dependent protein kinase II (CamKII, K_m = 300 μM) .

HY-P0270

Magainin 2 Magainin II	Bacterial Antibiotic Fungal	Infection
Magainin 2 (Magainin II) is an?antimicrobial?peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .

HY-P1821

Myelin Basic Protein MHP4-14	PKC	Neurological Disease
Myelin Basic Protein (MHP4-14), a synthetic peptide comprising residues 4-14 of myelin basic protein, is a very selective PKC substrate (K_m=7 μM). Myelin Basic Protein is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca ²⁺/calmodulin-dependent protein kinase II, or phosphorylase kinase, and can be routinely used for the assay of protein kinase C with low background in the crude tissue extracts .

HY-P5601

Thanatin	Bacterial Fungal	Infection
Thanatin is an inducible cationic antimicrobial peptide. Thanatin is a pathogen-inducible single-disulfide-bond-containing β-hairpin AMP. Thanatin displays broad-spectrum activity against both Gram-negative and Gram-positive bacteria as well as against various species of fungi with MICs of 0.3-40 µM, 0.6-40 µM and 0.6-20 µM, respectively. Thanatin has the property of competitive replacement of divalent cations from bacterial outer membrane (OM), leading to OM disruption .

HY-P5601A

Thanatin TFA	Bacterial Fungal	Infection
Thanatin TFA is an inducible cationic antimicrobial peptide. Thanatin TFA s a pathogen-inducible single-disulfide-bond-containing β-hairpin AMP. Thanatin TFA displays broad-spectrum activity against both Gram-negative and Gram-positive bacteria as well as against various species of fungi with MICs of 0.3-40 µM, 0.6-40 µM and 0.6-20 µM, respectively. Thanatin TFA has the property of competitive replacement of divalent cations from bacterial outer membrane (OM), leading to OM disruption .

HY-P1320

[Nphe1]Nociceptin(1-13)NH2	Opioid Receptor	Inflammation/Immunology
[Nphe1]Nociceptin(1-13)NH2, a novel nociceptin/orphanin FQ (NC) endogenous ligand, is a selective and competitive ociceptin receptor antagonist without any residual agonist activity. [Nphe1]nociceptin(1-13)NH2 binds selectively to recombinant nociceptin receptors (pK_i=8.4) and antagonizes the inhibitory effects of nociceptin on cyclic AMP accumulation in CHO cells (pA₂=6.0). [Nphe1]Nociceptin(1-13)NH2 has the potential to act as an analgesic agent .

HY-P1320A

[Nphe1]Nociceptin(1-13)NH2 TFA	Opioid Receptor	Inflammation/Immunology
[Nphe1]Nociceptin(1-13)NH2, a novel nociceptin/orphanin FQ (NC) endogenous ligand, is a selective and competitive ociceptin receptor antagonist without any residual agonist activity. [Nphe1]nociceptin(1-13)NH2?binds selectively to recombinant nociceptin receptors (pK_i=8.4) and antagonizes the inhibitory effects of nociceptin on cyclic AMP accumulation in CHO cells (pA₂=6.0). [Nphe1]Nociceptin(1-13)NH2 has the potential to act as an analgesic agent .

Cat. No.	Product Name	Target	Research Area

HY-P99169

Uliledlimab TJ004309	CD73	Cancer
Uliledlimab is a potent against CD73 humanizedized monoclonal antibody. Uliledlimab inhibits the conversion of extracellular adenosine monophosphate (AMP) to adenosine. Uliledlimab can be used in research of cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-12326A

*c-di-AMP* disodium** 2 Publications Verification Cyclic diadenylate disodium; Cyclic-di-AMP disodium	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	STING Bacterial Endogenous Metabolite
c-di-AMP (Cyclic diadenylate) sodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP sodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP sodium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .

HY-12326B

*c-di-AMP* diammonium** 2 Publications Verification Cyclic diadenylate diammonium; Cyclic-di-AMP diammonium	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	STING Bacterial Endogenous Metabolite
c-di-AMP diammonium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP diammonium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP diammonium acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .

HY-124151

Adenosine-2'-monophosphate 2'-AMP; Adenosine 2'-phosphate; AMP 2'-phosphate	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Adenosine Receptor Endogenous Metabolite
Adenosine-2'-monophosphate (2'-AMP) is converted by extracellular 2’,3'-CAMP. Adenosine-2'-monophosphate is further metabolized to extracellular adenosine (a mechanism called the extracellular 2’,3’-cAMP-adenosine pathway). Adenosine-2'-monophosphate inhibits LPS-induced TNF-α and CXCL10 production via A_2A receptor activation .

HY-B1511

Cyclic AMP 5+ Cited Publications Cyclic adenosine monophosphate; Adenosine cyclic 3', 5'-monophosphate; cAMP	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .

HY-100564A

2',3'-cGAMP sodium Maximum Cited Publications 14 Publications Verification 2'-3'-cyclic GMP-AMP sodium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite STING IFNAR
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP sodium is produced in mammalian cells in response to DNA in the cytoplasm .

HY-100564

2',3'-cGAMP Maximum Cited Publications 14 Publications Verification 2'-3'-cyclic GMP-AMP	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite STING IFNAR
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2',3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2',3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm .

HY-A0181

Adenosine monophosphate 5+ Cited Publications AMP	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

HY-A0181A

Adenosine 5'-monophosphate monohydrate 5+ Cited Publications 5'-AMP monohydrate	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Adenosine Receptor HSV Endogenous Metabolite
Adenosine 5'-monophosphate monohydrate is an adenosine A₁ receptor agonist. Adenosine 5'-monophosphate monohydrate has significant antiviral activity against HSV-1 and HSV-2.

HY-12326

c-di-AMP Cyclic diadenylate; Cyclic-di-AMP	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	STING Bacterial Endogenous Metabolite
c-di-AMP (Cyclic diadenylate) is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP (Cyclic diadenylate) is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response. c-di-AMP (Cyclic diadenylate) acts as a potent mucosal adjuvant stimulating both humoral and cellular responses .

HY-113401

Adenosine 2',3'-cyclic phosphate	Microorganisms Source classification	Endogenous Metabolite
Adenosine 2',3'-cyclic phosphate is a 2',3'-cyclic purine nucleotide. Adenosine 2',3'-cyclic phosphate can be degrade to 2'-AMP and 3'-AMP .

HY-129665

GS-389 (±)-O,O-Dimethylcoclaurine	Structural Classification Alkaloids Source classification Cocculus laurifolius DC. Plants Isoquinoline Alkaloids Menispermaceae	Endogenous Metabolite
GS 389 ((±)-O,O-Dimethylcoclaurine) is a tetrahydroisoquinoline. GS-389 inhibites Cyclic *AMP* and cyclic *AMP* dependent phosphodiesterases from rat atrial and ventricular tissue. GS-389 relaxes the contraction induced by phenylephrine and high K ⁺ in rat aortic rings .

HY-113284

Succinyladenosine N6-Succinyl adenosine	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency .

HY-W010759

Inosine-5′-monophosphate disodium salt octahydrate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Inosine-5'-monophosphate disodium salt octahydrate is a purine nucleotide that can be used as an umami tastant as well as a precursor of GMP and AMP .

HY-N8209

(+)-Medioresinol Di-O-β-D-glucopyranoside	Natural Products Eucommia ulmoides Oliver Classification of Application Fields Source classification Eucommiaceae Plants Disease Research Fields Inflammation/Immunology	Phosphodiesterase (PDE)
(+)-Medioresinol Di-O-β-D-glucopyranoside is a lignan glucoside with strong inhibitory activity of *3', 5'-cyclic monophosphate (cyclic AMP) phosphodiesterase* .

HY-127136

Griseolic acid	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Phosphodiesterase (PDE)
Griseolic acid a potent inhibitor of cyclic adenosine 3',5'-monophosphate (cyclic AMP) phosphodiesterase, with I₅₀ of 0.01-0.1 μM .

HY-N1289

Sequosempervirin B	Structural Classification Cupressaceae Source classification Phenols Polyphenols Plants Sequoia sempervirens (D. Don) Endl.	Fungal Phosphodiesterase (PDE)
Sequosempervirin B, a norlignan isolated from the branches and leaves of Sequoia sempervirens, has antifungal properties. Sequosempervirin B has an inhibitory effect on cyclic AMP phosphodiesterase .

HY-N7517

Adenosine 5′-monophosphoramidate sodium	Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Nucleoside Antimetabolite/Analog
Adenosine 5′-monophosphoramidate sodium is an adenosine derivative and can be used as an intermediate for nucleotide synthesis. Adenosine 5′-monophosphoramidate has a significant effect on the accumulation of cyclic AMP .

HY-110385

cGAMP disodium 10+ Cited Publications Cyclic GMP-AMP disodium; 3',3'-cGAMP disodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	STING Endogenous Metabolite
cGAMP (Cyclic GMP-AMPP) disodium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .

HY-110385A

cGAMP diammonium 10+ Cited Publications Cyclic GMP-AMP diammonium; 3',3'-cGAMP diammonium	Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Inflammation/Immunology	STING Endogenous Metabolite
cGAMP (Cyclic GMP-AMPP) diammonium functions as an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. cGAMP diammonium activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators .

HY-N6077

Thalidezine	Structural Classification Alkaloids Source classification Nelumbo nucifera Gaertn. Plants Nymphaeaceae Alkaloid Dimers	Others
Thalidezine is a novel activator of AMP-activated protein kinase (AMPK). Thalidezine can eliminate anti-apoptotic cancer cells through energy-mediated autophagy death. Thalidezine can be used to study apoptosis intervention .

HY-N6258

Kahweol	Structural Classification other families Classification of Application Fields Terpenoids Source classification Rubiaceae Metabolic Disease Diterpenoids Plants Disease Research Fields Coffea arabica L.	AMPK Apoptosis
Kahweol is one of the consituents of the coffee from Coffea Arabica with anti-inflammatory anti-angiogenic, and anti-cancerous activities. Kahweol inhibits adipogenesis and increase glucose uptake by AMP-activated protein kinase (AMPK) activation. Kahweol induces apoptosis.

HY-W016009

2'-Deoxyadenosine-5'-monophosphate	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage .

HY-N0579

Fraxin 3 Publications Verification Fraxoside	Structural Classification Oleaceae Classification of Application Fields Fraxinus rhynchophylla Hance Source classification Coumarins Plants Monophenols other families Phenols Phenylpropanoids Inflammation/Immunology Disease Research Fields	Phosphodiesterase (PDE)
Fraxin isolated from Cortex Fraxini, is a glucoside of fraxetin and reported to exert potent anti-oxidative stress action , anti-inflammatory and antimetastatic properties. Fraxin shows its antioxidative effect through inhibition of cyclo AMP phosphodiesterase enzyme .

HY-W105272

2′-Deoxyadenosine 5′-monophosphate disodium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage .

HY-N6258R

Kahweol (Standard)	Structural Classification other families Terpenoids Source classification Rubiaceae Diterpenoids Plants Coffea arabica L.	AMPK Apoptosis
Kahweol (Standard) is the analytical standard of Kahweol. This product is intended for research and analytical applications. Kahweol is one of the consituents of the coffee from Coffea Arabica with anti-inflammatory anti-angiogenic, and anti-cancerous activities. Kahweol inhibits adipogenesis and increase glucose uptake by AMP-activated protein kinase (AMPK) activation. Kahweol induces apoptosis.

HY-N0579R

Fraxin (Standard)	Structural Classification Monophenols other families Oleaceae Fraxinus rhynchophylla Hance Source classification Coumarins Phenols Phenylpropanoids Plants	Phosphodiesterase (PDE)
Fraxin (Standard) is the analytical standard of Fraxin. This product is intended for research and analytical applications. Fraxin isolated from Cortex Fraxini, is a glucoside of fraxetin and reported to exert potent anti-oxidative stress action , anti-inflammatory and antimetastatic properties. Fraxin shows its antioxidative effect through inhibition of cyclo AMP phosphodiesterase enzyme .

HY-N1074

Warangalone Scandenolone	Structural Classification Flavonoids Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields Isoflavones Erythrina variegata Linn.	Parasite PKA
Warangalone is an anti-malarial compound which can inhibit the growth of both strains of parasite 3D7 (chloroquine sensitive) and K1 (chloroquine resistant) with IC₅₀s of 4.8 μg/mL and 3.7 μg/mL, respectively. Warangalone can also inhibit *cyclic AMP-dependent protein kinase catalytic subunit* (cAK) with an IC₅₀ of 3.5 μM.

HY-P0270

Magainin 2 Magainin II	Infection Structural Classification Natural Products Animals Classification of Application Fields Source classification Disease Research Fields	Bacterial Antibiotic Fungal
Magainin 2 (Magainin II) is an?antimicrobial?peptide (AMP) isolated from the skin of the African clawed frog Xenopus laevis. Magainin 2 displays antibiotic activity against numerous gram-negative and gram-positive bacteria. Magainin 2 also is active against protozoa . Magainin 2 exerts its cytotoxicity effects by preferential interactions with anionic phospholipids abundant in bacterial membranes .

HY-100126

Tubercidin 5 Publications Verification 7-Deazaadenosine	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antiviral Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial DNA/RNA Synthesis Influenza Virus Antibiotic
Tubercidin (7-Deazaadenosine) is an antibiotic obtained from Streptomyces tubercidicus. Tubercidin inhibits the growth of Streptococcus faecalis (8043) with an IC₅₀ of 0.02 μM . Tubercidin inhibits polymerases by incorporating DNA or RNA, thereby inhibiting DNA replication, RNA and protein synthesis . Tubercidin is a weak inhibitor of adenosine phosphorylase, and interferes with the phosphorylation of adenosine and AMP . Tubercidin has antiviral activity .

HY-N7515

Pinocembrin chalcone 2',4',6'-Trihydroxychalcone	Structural Classification Chalcones Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	Bacterial AMPK
Pinocembrin chalcone (2',4',6'-Trihydroxychalcone) is an antibacterial compound from Helichrysum Trilineatum. Pinocembrin chalcone facilitates AMP-activated protein kinase (AMPK) activation, improves glucose tolerance, increases muscle FAO and reduces fat accumulation in the liver and skeletal muscles in high-fat diet-induced (HFD) diabetic mice. Pinocembrin chalcone is promising for research of gastric ulcers and diabetes .

HY-W016009R

2'-Deoxyadenosine-5'-monophosphate (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite	Endogenous Metabolite
2'-Deoxyadenosine-5'-monophosphate (Standard) is the analytical standard of 2'-Deoxyadenosine-5'-monophosphate. This product is intended for research and analytical applications. 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage .

HY-121197

Balanol Ophiocordin; Azepinostatin	Structural Classification Natural Products Microorganisms Source classification	MARCKS PKA PKC
Balanol (Ophiocordin; Azepinostatin) is a potent and ATP competitive PKC/PKA inhibitor against human PKC isozymes α, β-I, β-II, γ, δ, ε, η (IC₅₀s=4-9 nM) and ζ (IC₅₀=150 nM). Balanol also blocks the phosphorylation of *cyclic AMP* response element-binding protein (CREB) and myristoylated alanine-rich C kinase substrate (MARCKS)*. Balanol can be isolated from the fungus Verticillium balanoides* .

HY-113366

Prostaglandin J2 PGJ2	Structural Classification Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Prostaglandin Receptor Endogenous Metabolite
Prostaglandin J2 (PGJ2), an endogenous metabolite of Prostaglandin D2 (PGD2; HY-101988), is a potent PGD2 receptor (DP) agonist with K_is of 0.9 nM and 6.6 nM for hDP and hCRTH2, respectively. Prostaglandin J2 stimulates intracellular cyclic AMP production with an EC₅₀ value of 1.2 nM. Prostaglandin J2 induces oxidative stress and neuronal apoptosis. Prostaglandin J2 induces the accumulation/aggregation of ubiquitinated (Ub) proteins. Prostaglandin J2 is highly neurotoxic and potentially contributes to many neurodegenerative conditions, including Alzheimer's (AD) and Parkinson's diseases (PD) .

HY-N2055

Kaempferol 3-O-sophoroside	Panax ginseng C. A. Meyer Flavonols Structural Classification Classification of Application Fields Source classification Plants Flavonoids other families Phenols Polyphenols Inflammation/Immunology Disease Research Fields Araliaceae	Toll-like Receptor (TLR) NF-κB TNF Receptor AMPK
Kaempferol 3-O-sophoroside is an orally active derivative of Kaempferol. It exhibits anti-inflammatory, analgesic, and antidepressant effects. Kaempferol 3-O-sophoroside is an inhibitor of the cell surface receptor toll-like receptor (TLR) 2/4 for High mobility group box 1 (HMGB1), and it also exerts anti-inflammatory effects by blocking the activation of NF-κB expression and the production of TNF-α. Kaempferol 3-O-sophoroside promotes the production of brain-derived neurotrophic factor (BDNF) and enhances autophagy by binding to AMP-activated protein kinase (AMPK), thereby exerting antidepressant effects. Kaempferol 3-O-sophoroside holds promise for research in the fields of inflammation and neurodegenerative diseases .

Species:	Human (19) Rat (1)
Tag:	His (14) SUMO (2) Tag Free (2) GST (8) Flag (1) Fc (1)
Source:	HEK293 (3) Sf9 insect cells (9) E. coli (8)

Cat. No.	Compare	Product Name	Species	Source

HY-P70713

	NKG2A-CD94 Heterodimer Protein, Human (HEK293, His-Flag) NKG2A&AMP; CD94 Heterodimer; KLRC1&AMP; CD94 Heterodimer; CD159A&AMP; KLRD1 Heterodimer	Human	HEK293
	NKG2A Protein, a crucial immune inhibitory receptor, forms a complex with KLRD1 on lymphocyte subsets for self-nonself discrimination. Recognizing HLA-E loaded with self-peptides, it monitors MHC class I expression in healthy cells, promoting self-tolerance. NKG2A transmits signals through ITIMs, recruiting tyrosine phosphatases to counteractivate receptors. As a key inhibitor on NK cells, it regulates their functions, distinguishing harmless from pathogenic antigens. In the tumor microenvironment, NKG2A acts as an immune inhibitory checkpoint, contributing to cell exhaustion. During viral infection, it inhibits NK cell cytotoxicity, facilitating viral immune escape. NKG2A-CD94 Heterodimer Protein, Human (HEK293, His-Flag) is a recombinant protein dimer complex containing human-derived NKG2A-CD94 Heterodimer protein, expressed by HEK293, with N-Flag, N-8*His labeled tag. NKG2A-CD94 Heterodimer Protein, Human (HEK293, His-Flag), has molecular weight of 25-40 kDa.

HY-P76356

	Gastrokine 1 Protein, Human (sf9, His) 18 kDa antrum mucosa protein; AMP-18; Protein CA11; GKN1; AMP18; CA11	Human	Sf9 insect cells
	Gastrokine 1 protein exerts mitogenic activity, likely preserving the structural integrity of the gastric mucosal epithelium. Gastrokine 1 Protein, Human (sf9, His) is the recombinant human-derived Gastrokine 1 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Gastrokine 1 Protein, Human (sf9, His) is 165 a.a., with molecular weight of ~24 KDa.

HY-P74427

	Adenylate Kinase 1/AK1 Protein, Rat (His) Adenylate kinase isoenzyme 1; ATP-AMP transphosphorylase 1; AK1	Rat	E. coli
	The adenylate kinase 1 (AK1) protein plays a crucial role in cellular energy homeostasis by maintaining the balance of adenylate nucleotides by catalyzing the reversible transfer of terminal phosphate groups between ATP and AMP.Adenylate Kinase 1/AK1 Protein, Rat (His) is the recombinant rat-derived Adenylate Kinase 1/AK1 protein, expressed by E.coli , with N-His labeled tag.

HY-P74428

	Adenylate Kinase 1/AK1 Protein, Human (His) Adenylate kinase isoenzyme 1; ATP-AMP transphosphorylase 1; AK1	Human	E. coli
	Adenylate Kinase 1/AK1 Protein is an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. AK1 is highly expressed in skeletal muscle, brain and erythrocytes. It facilitates cellular energy dynamics by catalyzing the reversible transfer of the terminal phosphate group between ATP and AMP. In addition, AK1 displays nucleoside diphosphate kinase activity. Adenylate Kinase 1/AK1 Protein, Human (His) is the recombinant human-derived Adenylate Kinase 1/AK1 protein, expressed by E. coli , with N-His labeled tag. The total length of Adenylate Kinase 1/AK1 Protein, Human (His) is 194 a.a., with molecular weight of ~23 kDa.

HY-P76284

	CREB3L1 Protein, Human (HEK293, His) Cyclic AMP-responsive element-binding protein 3-like protein 1; OASIS	Human	HEK293
	CREB3L1 protein is located on the endoplasmic reticulum membrane and is converted into a transcription factor processing cyclic AMP response element binding protein 3-like protein 1. During endoplasmic reticulum stress or DNA damage, it translocates to the Golgi apparatus, is cleaved by S1P/MBTPS1 and S2P/MBTPS2, and releases a cytoplasmic domain that activates gene transcription in the nucleus. CREB3L1 Protein, Human (HEK293, His) is the recombinant human-derived CREB3L1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P7615

	ATF1 Protein, Human (His) rHuATF1, His; Cyclic AMP-dependent transcription factor ATF-1; cAMP-dependent transcription factor ATF-1; Activating transcription factor 1	Human	E. coli
	ATF1 Protein, Human (His) expressed in E. coli with a His tag. ATF1 is a member of the ATF/CREB family of transcription factors (TFs), specifically interacting with the consensus ATF/CRE site ‘TGACGTCA’.

HY-P700576

	AK1 Protein, Human (His-SUMO) Adenylate kinase isoenzyme 1; ATP-AMP transphosphorylase 1	Human	E. coli
	The AK1 protein contributes to cellular energy dynamics by catalyzing the reversible transfer of terminal phosphate groups between ATP and AMP. In addition to its primary role, AK1 exhibits nucleoside diphosphate kinase activity, utilizing ATP or GTP as a phosphate donor to generate ATP, CTP, GTP, UTP, dATP, dCTP, dGTP, and dTTP. AK1 Protein, Human (His-SUMO) is the recombinant human-derived AK1 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of AK1 Protein, Human (His-SUMO) is 194 a.a., with molecular weight of 37.6 kDa.

HY-P702608

	AK2 Protein, Human (GST) Adenylate kinase 2; AK 2; ATP-AMP transphosphorylase 2; ADK2	Human	E. coli
	AK2 protein plays a key role in cellular energy homeostasis and adenine nucleotide metabolism by catalyzing the reversible transfer of terminal phosphate groups between ATP and AMP. Its adenylate kinase activity plays a key role in regulating phosphate utilization and de novo AMP biosynthetic pathways, contributing to the complex balance of cellular energy resources. AK2 Protein, Human (GST) is the recombinant human-derived AK2, expressed by E. coli , with N-GST labeled tag. The total length of AK2 Protein, Human (GST) is 239 a.a.,

HY-P76716

	AK3L1 Protein, Human (sf9) Adenylate kinase 4; Adenylate kinase 3-like; GTP:AMP phosphotransferase AK4; AK3	Human	Sf9 insect cells
	The AK3L1 protein actively maintains cellular nucleotide homeostasis by catalyzing the interconversion of nucleoside phosphates. This multifunctional enzyme efficiently phosphorylates AMP and dAMP using ATP as a phosphate donor, and selectively phosphorylates AMP when utilizing GTP. AK3L1 Protein, Human (sf9) is the recombinant human-derived AK3L1 protein, expressed by Sf9 insect cells , with tag free. The total length of AK3L1 Protein, Human (sf9) is 222 a.a., with molecular weight of ~27 kDa.

HY-P76717

	AK3L1 Protein, Human (sf9, His-GST) Adenylate kinase 4; Adenylate kinase 3-like; GTP:AMP phosphotransferase AK4; AK3	Human	Sf9 insect cells
	The AK3L1 protein actively maintains cellular nucleotide homeostasis by catalyzing the interconversion of nucleoside phosphates. This multifunctional enzyme efficiently phosphorylates AMP and dAMP using ATP as a phosphate donor, and selectively phosphorylates AMP when utilizing GTP. AK3L1 Protein, Human (sf9, His-GST) is the recombinant human-derived AK3L1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of AK3L1 Protein, Human (sf9, His-GST) is 222 a.a., with molecular weight of ~46 kDa.

HY-P702979

	AMPKG1 Protein, Human (sf9, GST) 5'-AMP-activated protein kinase subunit gamma-1; AMPK gamma1; AMPK subunit gamma-1; AMPKg; PRKAG1	Human	Sf9 insect cells
	AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK) and is an important regulator of cellular energy metabolism. It is activated by low ATP levels, enhancing energy production while inhibiting biosynthetic processes and cell growth. AMPKG1 Protein, Human (sf9, GST) is the recombinant human-derived AMPKG1, expressed by Sf9 insect cells , with GST labeled tag. The total length of AMPKG1 Protein, Human (sf9, GST) is 331 a.a.,

HY-P702656

	NUAK1 Protein, Human (sf9, GST) NUAK1; NUAK family, SNF1-like kinase, 1; NUAK family SNF1-like kinase 1; AMP activated protein kinase family member 5; ARK5; KIAA0537; NuaK1; omphalocele kinase 1; AMPK-related protein kinase 5; AMP-activated protein kinase family member 5	Human	Sf9 insect cells
	NUAK1 Protein, Human (sf9, GST) is the recombinant human-derived NUAK1, expressed by Sf9 insect cells , with GST labeled tag. ,

HY-P72337

	cGAS Protein, Human (His) 1 Publications Verification Cyclic GMP-AMP synthase; cGAMP synthase; h-cGAS; 2'3'-cGAMP synthase; Mab-21 domain-containing protein 1; MB21D1; C6orf150	Human	E. coli
	The cGAS protein is a nucleotidyl transferase that crucially mediates innate immunity by catalyzing the formation of 2',3'-cGAMP from ATP and GTP upon binding to double-stranded DNA (dsDNA). As a DNA sensor, cGAS detects exogenous and endogenous DNA, triggering STING1 activation and type I interferon production. cGAS Protein, Human (His) is the recombinant human-derived cGAS protein, expressed by E. coli , with C-6*His labeled tag. The total length of cGAS Protein, Human (His) is 522 a.a., with molecular weight of ~58.9 kDa.

HY-P76141

	AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) 1 Publications Verification 5'-AMP-activated protein kinase; AMPK; AMPK (α1, β1, γ1) Protein	Human	Sf9 insect cells
	AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK) and is an important regulator of cellular energy metabolism. It is activated by low ATP levels, enhancing energy production while inhibiting biosynthetic processes and cell growth. AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) is the recombinant human-derived AMPK gamma 1/beta 1/alpha 1 Heterotrimer protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. AMPK gamma 1/beta 1/alpha 1 Heterotrimer Protein, Human (sf9, His-GST), has molecular weight of 38 (beta-1)&40 (gamma-1)&95 (alpha-1) kDa, respectively.

HY-P76142

	AMPK gamma 1/beta 1/alpha 2 Heterotrimer Protein, Human (sf9, His-GST) 5'-AMP-activated protein kinase; AMPK; AMPK (α2, β1, γ1) Protein	Human	Sf9 insect cells
	The AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), a crucial regulator of cellular energy metabolism. Activated by low ATP levels, it enhances energy production while suppressing biosynthetic processes and cell growth. The gamma subunit mediates AMP, ADP, and ATP binding, influencing AMPK activation or inhibition. Allosteric AMP binding activates the alpha subunit, while ADP stimulates phosphorylation, and ATP promotes dephosphorylation, rendering AMPK inactive. Additionally, AMPK modulates cellular polarity and interacts with FNIP1 and FNIP2. AMPK gamma 1/beta 1/alpha 2 Heterotrimer Protein, Human (sf9, His-GST) is the recombinant human-derived AMPK gamma 1/beta 1/alpha 2 Heterotrimer protein, expressed by Sf9 insect cells, with N-His, N-GST, N-10*His labeled tag. AMPK gamma 1/beta 1/alpha 2 Heterotrimer Protein, Human (sf9, His-GST), has molecular weight of ~40 & 42 & 95 KDa, respectively.

HY-P76143

	AMPK gamma 1/beta 2/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) 5'-AMP-activated protein kinase; AMPK; AMPK (α1, β2, γ1) Protein	Human	Sf9 insect cells
	The AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), a crucial regulator of cellular energy metabolism. Activated by low ATP levels, it enhances energy production while suppressing biosynthetic processes and cell growth. The gamma subunit mediates AMP, ADP, and ATP binding, influencing AMPK activation or inhibition. Allosteric AMP binding activates the alpha subunit, while ADP stimulates phosphorylation, and ATP promotes dephosphorylation, rendering AMPK inactive. Additionally, AMPK modulates cellular polarity and interacts with FNIP1 and FNIP2. AMPK gamma 1/beta 2/alpha 1 Heterotrimer Protein, Human (sf9, His-GST) is the recombinant human-derived AMPK gamma 1/beta 2/alpha 1 Heterotrimer protein, expressed by Sf9 insect cells, with N-His, N-GST labeled tag. AMPK gamma 1/beta 2/alpha 1 Heterotrimer Protein, Human (sf9, His-GST), has molecular weight of ~35 & 37 & 95 KDa, respectively.

HY-P76144

	AMPK gamma 1/beta 2/alpha 2 Heterotrimer Protein, Human (sf9, His-GST) 5'-AMP-activated protein kinase; AMPK; AMPK (α2, β2, γ1) Protein	Human	Sf9 insect cells
	AMPK gamma 1 is the AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK) and is an important regulator of cellular energy metabolism. It is activated by low ATP levels, enhancing energy production while inhibiting biosynthetic processes and cell growth. AMPK gamma 1/beta 2/alpha 2 Heterotrimer Protein, Human (sf9, His-GST) is the recombinant human-derived AMPK gamma 1/beta 2/alpha 2 Heterotrimer protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. AMPK gamma 1/beta 2/alpha 2 Heterotrimer Protein, Human (sf9, His-GST), has molecular weight of ~35 & 37 & 95 KDa, respectively.

HY-P703577

	PDE7A1 Protein, Human High affinity 3',5'-cyclic-AMP phosphodiesterase 7A; HCP1; TM22; cAMP-specific phosphodiesterase 7A; PDE7A; Homo sapiens; Human; Hydrolase; 3.1.4.53	Human	E. coli
	PDE7A1 Protein, Human is the recombinant human-derived PDE7A1, expressed by E. coli , with tag Free labeled tag. ,

HY-P70655

	IL-15R alpha & IL-15 Protein, Human (HEK293, Fc) IL15RA&AMP; IL15; Interleukin-15; IL-15; IL15; IL-15 receptor subunit alpha; IL-15RA; IL-15R-alpha; interleukin-15 receptor subunit alpha	Human	HEK293
	IL-15R alpha is a high affinity receptor for IL-15 (K_d: 100 pM). IL-15 is essential for the development and function natural killer (NK) cell, NKT cell and memory (m) CD8+ T cell. IL-15R alpha maintains memory CD8+ T cell homeostasis and lymphocyte development. IL-15R alpha/IL-15 complex can activate the antitumor functions of NK cells and CD8+ T cells. IL-15R alpha & IL-15 Protein, Human (HEK293, Fc) is a recombinant human IL-15R alpha (I31-D96) & IL-15 (N49-S162) fusion protein with a C-Terminal hFc tag, which is produced in HEK293 cells.

HY-P71597

	cGAS Protein, Human (His-SUMO) C6orf150; cGAMP synthase; cGAS; CGAS_HUMAN; cGMP Synthase; Chromosome 6 open reading frame 150; Cyclic GMP-AMP synthase; h-cGAS; Hypothetical protein LOC115004; Mab 21 domain containing 1; Mab-21 domain-containing protein 1; MB21D1; MGC131892; MGC142166; MGC142168; OTTHUMP00000016743; OTTHUMP00000039330; protein MB21D1; Uncharacterized protein C6orf150	Human	E. coli
	The cGAS protein is a nucleotidyl transferase that crucially mediates innate immunity by catalyzing the formation of 2',3'-cGAMP from ATP and GTP upon binding to double-stranded DNA (dsDNA). As a DNA sensor, cGAS detects exogenous and endogenous DNA, triggering STING1 activation and type I interferon production. cGAS Protein, Human (His-SUMO) is the recombinant human-derived cGAS protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-B0272S

Rifampicin-d3
Rifampicin-d₃ is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities[1][2].

HY-B0272S2

Rifampicin-d4
Rifampicin-d₄ is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.

HY-B1511S

*Cyclic AMP-13C5*
Cyclic AMP- ¹³C₅ is a deuterated cyclic AMP.

HY-A0181S2

Adenosine monophosphate-d12 dilithium
Adenosine monophosphate-d₁₂ (AMP-d₁₂) dilithium is deuterium labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

HY-A0181S3

Adenosine monophosphate-13C10 dilithium
Adenosine monophosphate- ¹³C₁₀ (AMP- ¹³C₁₀) dilithium is ¹³C-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

HY-B0272S3

Rifampicin-d11
Rifampicin-d₁₁ (Rifampin-d₁₁; Rifamycin AMP-d₁₁)is the deuterium labeledRifampicin(HY-B0272) . Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities. Rifampicin shows anti-orthopoxvirus activity .

HY-A0181S5

Adenosine monophosphate-15N5,d12 dilithium
Adenosine monophosphate- ¹⁵N₅,d₁₂ (AMP- ¹⁵N₅,d₁₂) dilithium is deuterium and ¹⁵N labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

HY-A0181S4

Adenosine monophosphate-13C10,15N5,d12 dilithium
Adenosine monophosphate- ¹³C₁₀, ¹⁵N₅,d₁₂ (AMP- ¹³C₁₀, ¹⁵N₅,d₁₂) dilithium is ¹³C and ¹⁵N-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

HY-B0272S1

Rifampicin-d8
Rifampicin-d8 (Rifampin-d8) is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.

HY-B0763S1

Ibudilast-d7

Ibudilast-d₇ is the deuterium labeled Ibudilast. Ibudilast (KC-404; AV-411; MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[1].

HY-W016009S

2'-Deoxyadenosine-5'-monophosphate-d12 dilithium
2'-Deoxyadenosine-5'-monophosphate-d₁₂ dilithium is deuterium labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.

HY-W016009S3

2'-Deoxyadenosine-5'-monophosphate-13C10 dilithium
2'-Deoxyadenosine-5'-monophosphate- ¹³C₁₀ dilithium is ¹³C-labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.

HY-W016009S2

2'-Deoxyadenosine-5'-monophosphate-15N5 dilithium
2'-Deoxyadenosine-5'-monophosphate- ¹⁵N₅ dilithium is ¹⁵N labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.

HY-10250S1

Triciribine phosphate-d3

Triciribine phosphate-d3 (TCN-P-d3) is a deuterated compound of Triciribine phosphate (TCN-P). TCN-P inhibits adenosine monophosphate (AMP)-activated protein kinase through an allosteric mechanism, affecting the first key step in de novo purine biosynthesis. Triciribine phosphate also inhibits inosine monophosphate dehydrogenase, which is the first key step in guanosine nucleotide synthesis. Triciribine phosphate does not affect ligase activity .

HY-B0763S2

Ibudilast-d7-1

Ibudilast-d₇-1 is the deuterium labeled Ibudilast[1]. Ibudilast (KC-404;AV-411;MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[2].

HY-W105272S

2′-Deoxyadenosine 5′-monophosphate-13C10,15N5 disodium

2′-Deoxyadenosine 5′-monophosphate- ¹³C₁₀, ¹⁵N₅ (disodium) is the ¹³C and ¹⁵N labeled 2′-Deoxyadenosine 5′-monophosphate disodium[1]. 2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[2].

HY-W016009S4

2'-Deoxyadenosine-5'-monophosphate-13C10,15N5 dilithium
2'-Deoxyadenosine-5'-monophosphate- ¹³C₁₀, ¹⁵N₅ dilithium is ¹³C and ¹⁵N-labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.

HY-W016009S1

2'-Deoxyadenosine-5'-monophosphate-15N5,d12 dilithium
2'-Deoxyadenosine-5'-monophosphate- ¹⁵N₅,d₁₂ dilithium is deuterium and ¹⁵N labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.

HY-A0181S

Adenosine monophosphate-13C10,15N5 1 Publications Verification
Adenosine monophosphate- ¹³C₁₀, ¹⁵N₅ is the ¹³C-labeled and ¹⁵N-labeled Adenosine monophosphate. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction[1].

HY-A0181BS

Adenosine monophosphate-13C10,15N5 disodium 1 Publications Verification
Adenosine monophosphate-13C10,15N5 (disodium) is the sodium salt form of Adenosine monophosphate-13C10,15N5. Adenosine monophosphate is a key cellular metabolite that regulates energy homeostasis and signal transduction .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80542

	AMPK beta 1 Antibody 5' ' -AMP-activated protein kinase subunit beta-1; AMP-activated; noncatalytic; beta-1; AMPK; AMPK beta 1 chain; AMPK subunit beta-1; AMPK-BETA-1; AMPKb; HAMPKb; PRKAB1	WB, IHC-P, FC, IP	Human, Mouse, Rat
	AMPK beta 1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 30 kDa, targeting to AMPK beta 1. It can be used for WB,IHC-P,FC,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P80793

	Phospho-ATF2 (Thr71) Antibody ATF2; CREB2; CREBP1; Cyclic AMP-dependent transcription factor ATF-2; cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding pro	WB, ICC/IF, IP	Human, Mouse
	Phospho-ATF2 (Thr71) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 55 kDa, targeting to Phospho-ATF2 (Thr71). It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Mouse.

HY-P80970

	FMRP Antibody CREB1; Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1	WB, ICC/IF, IHC-P	Human, Mouse, Rat
	FMRP Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 71 kDa, targeting to FMRP. It can be used for WB, IF-Cell, IF-Tissue, IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P80553

	ATF4 Antibody Cyclic AMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; DNA-binding protein TAXREB67	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	ATF4 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 39 kDa, targeting to ATF4. It can be used for WB,IHC-P,ICC/IF,IP,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P80805

	Phospho-CREB (Ser133) Antibody (YA209) CREB1; Cyclic AMP-responsive element-binding protein 1; CREB-1; cAMP-responsive element-binding protein 1	WB, IHC-P, IP	Human, Rat
	Phospho-CREB (Ser133) Antibody (YA209) is a non-conjugated and Rabbit origined monoclonal antibody about 35 kDa, targeting to Phospho-CREB (Ser133). It can be used for WB,IHC-P,IP assays with tag free, in the background of Human, Rat.

HY-P82439

	ATF5 Antibody (YA2184) ATF5; ATFX; Cyclic AMP-dependent transcription factor ATF-5; cAMP-dependent transcription factor ATF-5; Activating transcription factor 5; Transcription factor ATFx	WB, IHC-P, IP	Human, Mouse, Rat
	ATF5 Antibody (YA2184) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2184), targeting ATF5, with a predicted molecular weight of 31 kDa (observed band size: 31 kDa). ATF5 Antibody (YA2184) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

HY-P80541

	AMPK alpha Antibody PRKAA2; AMPK; AMPK2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase	WB, IP	Human
	AMPK alpha Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 62 kDa, targeting to AMPK alpha. It can be used for WB,IP assays with tag free, in the background of Human .

HY-P83667

	Phospho-ATF4 (Ser219) Antibody Cyclic AMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; DNA-binding protein TAXREB67	WB	Human

HY-P83391

	ATF1 Antibody (YA3136) Cyclic AMP-dependent transcription factor ATF-1; cAMP-dependent transcription factor ATF-1; Activating transcription factor 1 Protein TREB36; ATF1	WB, ICC/IF, IP	Human
	ATF1 Antibody (YA3136) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3136), targeting ATF1, with a predicted molecular weight of 29 kDa (observed band size: 36 kDa). ATF1 Antibody (YA3136) can be used for WB, ICC/IF, IP experiment in human background.

HY-P82906

	ATF7 Antibody (YA2651) ATF7; ATFA; Cyclic AMP-dependent transcription factor ATF-7; cAMP-dependent transcription factor ATF-7; Activating transcription factor 7; Transcription factor ATF-A	WB	Human, Mouse, Rat
	ATF7 Antibody (YA2651) is a biotin-conjugated non-conjugated IgG antibody, targeting ATF7, with a predicted molecular weight of 52 kDa (observed band size: 52 kDa). ATF7 Antibody (YA2651) can be used for WB experiment in human, mouse, rat background.

HY-P80540

	AMPK alpha 2 Antibody (YA623) PRKAA2; AMPK; AMPK2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase	WB, IP	Human, Rat
	AMPK alpha 2 Antibody (YA623) is a non-conjugated and Rabbit origined monoclonal antibody about 62 kDa, targeting to AMPK alpha 2. It can be used for WB,IP assays with tag free, in the background of Human, Rat.

HY-P80791

	Phospho-AMPK alpha 2 (Thr172) Antibody PRKAA2; AMPK; AMPK2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase	WB	Human, Mouse, Rat
	Phospho-AMPK alpha 2 (Thr172) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 62 kDa, targeting to Phospho-AMPK alpha 2 (Thr172). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80539

	AMPK alpha 1 Antibody PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	AMPK alpha 1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 64 kDa, targeting to AMPK alpha 1. It can be used for WB,IHC-P,ICC/IF,IP,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P80790

	Phospho-AMPK alpha 1 (Ser496) Antibody PRKAA1; AMPK1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	Phospho-AMPK alpha 1 (Ser496) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 64 kDa, targeting to Phospho-AMPK alpha 1 (Ser496). It can be used for WB,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P80552

	ATF2 Antibody Activating transcription factor 2 antibody; Activating transcription factor 2 splice variant ATF2 var2 antibody; ATF 2 antibody; Atf-2 antibody; Atf2 antibody; ATF2 protein antibody; ATF2_HUMAN antibody; cAMP Response Element Binding Protein 2 antibody; cAMP response element binding protein CRE BP1 antibody; cAMP response element-binding protein CRE-BP1 antibody; cAMP responsive element binding protein 2, formerly antibody; cAMP-dependent transcription factor ATF-2 antibody; cAMP-responsive element-binding protein 2 antibody; CRE BP1 antibody; CRE-BP antibody; CREB 2 antibody; CREB-2 antibody; CREB2 antibody; CREBP1 antibody; Cyclic AMP dependent transcription factor ATF 2 antibody; Cyclic AMP-dependent transcription factor ATF-2 antibody; Cyclic AMP-responsive element-binding protein 2 antibody; D130078H02Rik antibody; D18875 antibody; HB 16 antibody; HB16 antibody; Histone acetyltransferase ATF2 antibody; MGC105211 antibody; MGC105222 antibody; MGC111558 antibody; MGC142504 antibody; mXBP antibody; MXBP protein antibody; Tg(Gzma-Klra1)7Wum antibody; TREB 7 antibody; TREB7 antibody	WB	Human, Mouse, Rat
	ATF2 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 52 kDa, targeting to ATF2. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.