Search Result
Results for "
nanoparticle
" in MedChemExpress (MCE) Product Catalog:
205
Biochemical Assay Reagents
11
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P99974
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nanoparticle albumin-bound Paclitaxel; nanoparticle albumin-bound ABI-007
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Microtubule/Tubulin
Apoptosis
Autophagy
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Cancer
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Nab-Paclitaxel is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015). Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel (Paclitaxel: human albumin=1:9), in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug. Nab-Paclitaxel was associated with higher response rates and better tolerability, with favorable pharmacokinetic properties . (The product size below only indicate the effective content of Paclitaxel. The actual albumin quality depends on the batch. The ratio of each component in this product is Paclitaxel: albumin = 1:7-1:11.)
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- HY-141629
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Sphingomyelin 16:0
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Liposome
Endogenous Metabolite
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Others
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N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles .
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- HY-148648
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Liposome
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Others
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Lipid 29 is an ionizable amino lipid. Lipid 29 can be used to form lipid nanoparticles .
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- HY-158796
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Liposome
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Others
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L202 is an ionizable cationic lipid (pKa=6.04) that can be used for the study of mRNA and lipid nanoparticles .
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- HY-159725
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Liposome
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Others
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BAmP-O16B is an ionizable cationic amino lipid that can be used to generate lipid nanoparticles (LNPs) .
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- HY-W441014
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DSPE-PEG2000-NHS
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Liposome
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Others
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DSPE-PEG-NHS, MW 2000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
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- HY-168392
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Biochemical Assay Reagents
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Others
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Propylene glycol monopalmitate can be used to synthesize solid lipid nanoparticles (SLNs) for the delivery of bioactive compounds .
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- HY-153187
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Liposome
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Others
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LNP Lipid-4 (Compound 8-8) is a lipid compound. LNP Lipid-4 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-4 has potential applications in the transportation of biologically active substances .
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- HY-150241
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Liposome
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Others
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DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .
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- HY-168381
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Biochemical Assay Reagents
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Others
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Lipid A6 is a biodegradable alkyne lipid that can be used to synthesize lipid-like nanoparticles (LNPs) for delivery of mRNA .
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- HY-126721
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- HY-W040193
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DSPC
4 Publications Verification
1,2-Distearoyl-sn-glycero-3-PC; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine
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Liposome
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Others
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DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
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- HY-134541
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SM-102
Maximum Cited Publications
19 Publications Verification
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Liposome
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Infection
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SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
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- HY-W040193A
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1,2-Distearoyl-sn-glycero-3-PC (Excipient); 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (Excipient)
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Liposome
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Others
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DSPC Excipient (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC Excipient is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
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- HY-46759
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Liposome
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Infection
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Genevant CL1 is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery [1][2].
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- HY-134541A
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Liposome
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Infection
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SM-102 Excipient is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 Excipient has higher transfection efficiency. SM-102 Excipient plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
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- HY-133952
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Liposome
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Cancer
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7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents .
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- HY-141674
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Liposome
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Metabolic Disease
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DMG-PEG is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
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- HY-143700
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- HY-W094581
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Biochemical Assay Reagents
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Others
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Gold (III) chloride trihydrate is a reducing agent. Gold (III) chromium trihydrate can be used for chemical synthesis of gold nanoparticles (NP) and spirochromene derivatives .
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- HY-Y0102
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2-Mercaptobenzoic acid
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Biochemical Assay Reagents
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Others
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Thiosalicylic acid (2-Mercaptobenzoic acid) is a stabilizer that can be used in the synthesis of metal nanoparticles. Thiosalicylic acid is a biomaterial or organic compound that can be used in life science research .
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- HY-D2514
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Fluorescent Dye
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Others
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Cy3-PEG-DSPE (MW 1000) is a compound for the labeling and visualization of nanoparticles or other materials. Cy3-PEG-DSPE (MW 1000) has a variety of applications including drug delivery, cellular imaging, tracing of bioprocesses, and the study of interactions at the molecular level.
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- HY-D2518
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Fluorescent Dye
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Others
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Cy3-PEG-DSPE (MW 10000) is a compound for the labeling and visualization of nanoparticles or other materials. Cy3-PEG-DSPE (MW 10000) has a variety of applications including drug delivery, cellular imaging, tracing of bioprocesses, and the study of interactions at the molecular level.
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- HY-159717
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Liposome
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Others
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Lipid 331 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 331 is a carrier for both siRNA and mRNA .
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- HY-159865
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Liposome
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Others
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CL15F6 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
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- HY-159726
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Liposome
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Others
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C10-200 is an ionizable cationic lipid that can be used to generate lipid nanoparticles (LNPs). C10-200 is used in the study of mRNA delivery .
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- HY-145794
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Liposome
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Cancer
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ZA3-Ep10 is a zwitterionic lipid used in lipid nanoparticles formulation for in vivo RNA delivery and non-viral CRISPR/Cas gene editing.
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- HY-159856
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Diphosphatidylglycerol (16:0)
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Liposome
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Others
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16:0 Cardiolipin (Diphosphatidylglycerol (16:0)) is a phospholipid derived from Palmitic acid (16:0) that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
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- HY-159709
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Liposome
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Others
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VL-422 is an ionizable cationic lipid that can be used for lipid nanoparticle (LNP) and drug delivery research .
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- HY-159862
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Liposome
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Infection
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IM21.7c is a cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
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- HY-159716
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Liposome
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Others
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Lipid 50 (compound 50) is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 50 is a carrier for both siRNA and mRNA .
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- HY-159715
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Liposome
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Others
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Lipid DIM1 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid DIM1 is a carrier for both siRNA and mRNA .
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- HY-159714
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Liposome
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Others
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Lipid HTO12 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid HTO12 is a carrier for both siRNA and mRNA .
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- HY-159853
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Liposome
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Inflammation/Immunology
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C14-A1 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
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- HY-148033
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N,N,N-Trimethylchitosan
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Drug Derivative
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Others
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Trimethyl chitosan (N,N,N-Trimethylchitosan) is a water-soluble multifunctional polymer which is a Chitosan (HY-B2144A) derivative. Trimethyl chitosan can be used for drug delivery and to synthesize nanoparticles .
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- HY-159854
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Liposome
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Cancer
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C14-O2 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
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- HY-P10510
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Biochemical Assay Reagents
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Others
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R5 peptide is one of the repeating peptide sequences that form the protein diatom in Cylindrotheca fusiformis. R5 peptide can be used as a template for the synthesis of Pd (palladium) nanoparticles (NPs). R5 peptide forms complexes with metal ions through the amine groups in its sequence, and the self-assembled structure of the peptide provides a confined spatial environment for the reduction of metal ions and the nucleation of nanoparticles. R5 peptide can be used in the research of biomimetic nanomaterials .
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- HY-138170
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Liposome
SARS-CoV
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Infection
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ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
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- HY-153376
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Liposome
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Others
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LNP Lipid-6 (Compound Lipid 5) is an ionizable lipid (amino lipid). LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) .
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- HY-153375
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Liposome
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Others
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LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP) .
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- HY-P10679
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MMP
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Cancer
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GPLGLAGGWGERDGS is a peptide with MMP enzyme responsiveness and tumor targeting function, which can be used to monitor enzyme-guided nanoparticle assembly in tumors .
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- HY-138170A
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Liposome
SARS-CoV
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Infection
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ALC-0315 Excipient is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 Excipient can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
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- HY-160045
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Cholecystokinin Receptor
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Cancer
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AP1153 aptamer sodium is a DNA aptamer that specifically binds to the cholecystokinin receptor CCKBR (Kd: ~15 pM), but does not activate CCKBR-related signaling pathways. AP1153 aptamer sodium is internalized by pancreatic ductal adenocarcinoma (PDAC) cells in a receptor-mediated manner. AP1153 aptamer sodium can bioconjugate to the surface of fluorescent nanoparticles to facilitate nanoparticle delivery to PDAC tumors in vivo .
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- HY-160439
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Liposome
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Others
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Ionizable lipid-2 (compound 1) is an ionizable lipid used for nucleic acid delivery and construct lipid nanoparticles (LNPs) .
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- HY-148363
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Liposome
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Inflammation/Immunology
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Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .
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- HY-P5533
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Biochemical Assay Reagents
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Cancer
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CRT, an iron peptide mimic, can bind to apo-transferrin (apo-Tf). CRT can be used to modify nanoparticles, and enhances drug delivery efficiency .
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- HY-W035091
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Biochemical Assay Reagents
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Others
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Tetrachloroauric acid is an inorganic compound with the chemical formula H[AuCl4] and can be formed when gold is dissolved in aqua regia. Tetrachloroauric acid can be utilized in gold plating or preparation of gold nanoparticles .
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- HY-151507
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Liposome
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Others
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306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
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- HY-W440835
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DSPE-PEG(2000)-DBCO
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Liposome
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Others
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DSPE-PEG-DBCO, MW 2000 is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG-DBCO, MW 2000 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- HY-155902B
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Maleimide-PEG-Hydroxy (MW 1000)
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Biochemical Assay Reagents
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Others
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Mal-PEG-OH (MW 1000) was used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
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- HY-159855
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Cholesterol-amino-phosphate 2 hydrochloride
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Liposome
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Others
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CAP 2 (Cholesterol-amino-phosphate 2) hydrochloride is Cholesterol-amino-phosphate (CAP) lipid. CAP 2 can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
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- HY-155902A
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Maleimide-PEG-Hydroxy (MW 2000)
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Biochemical Assay Reagents
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Others
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Mal-PEG-OH (MW 2000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
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- HY-155902
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Maleimide-PEG-Hydroxy (MW 5000)
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Biochemical Assay Reagents
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Others
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Mal-PEG-OH (MW 5000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
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- HY-171114
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Liposome
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Others
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DMT7 is an ionizable cationic lipid (pKa = 6.5) that can be used to generate lipid nanoparticles (LNPs) for delivery of mRNA and anticancer drugs in the body .
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- HY-P1781A
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Secretin Receptor
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Cancer
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Peptide C105Y TFA, a synthetic and cell-penetrating peptide based on the amino acid sequence corresponding to residues 359-374 of α1-antitrypsin, enhances gene expression from DNA nanoparticles .
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- HY-W441002
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Liposome
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Others
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DSPE-succinic acid is a phophalipid capped with a carboxylic acid moiety. The carboxylic acid moiety is reactive with amine to from a stable amide linkage. DSPE-succinic acid can be used to prepare nanoparticles or liposomes for agent nanocarrier to deliver therapeutics .
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- HY-158255
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Biochemical Assay Reagents
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Others
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mPEG-PLGA (2000-80000) (LA/GA 50:50) is a copolymer, which consists of hydrophilic mPEG and biodegradable PLGA (molar ratio is 50:50) with a molecular weight of 2000 (mPEG) + 80000 (PLGA). mPEG-PLGA (2000-80000) (LA/GA 50:50) forms nanoparticles or microparticles, which is stable in aqueous solution at different pH values and elevated temperatures as well as in serum. mPEG-PLGA (2000-80000) (LA/GA 50:50) is utilized as carrier material in drug delivery systems .
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- HY-P10646
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Biochemical Assay Reagents
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Neurological Disease
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Muscle homing peptide M12 can preferentially bind to surface protein of muscle cells. Muscle homing peptide M12 mediates enhanced cellular uptake of nanoparticles (NPs) in myoblasts in vitro. Muscle homing peptide M12 is covalently conjugated to PLGA-PEG NPs via the N-terminal α-amino groups of peptides using the N-hydroxysuccinimide ester reaction .
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- HY-159858
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Liposome
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Cancer
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Lipid 16 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads. Lipid 16 as a potent cell type-specific ionizable lipid for the CD11bhi macrophage population without an additional targeting moiety .
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- HY-W105426
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[3-(Methacryloyloxy)propyl]trimethoxysilane
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Biochemical Assay Reagents
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Others
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3-(Trimethoxysilyl)propyl methacrylate ([3-(Methacryloyloxy)propyl]trimethoxysilane) is a silane coupling agent that can be used to modify TiO2 nanoparticles. 3-(Trimethoxysilyl)propyl methacrylate is a biomaterial or organic compound that can be used for life science research .
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- HY-159869
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Liposome
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Others
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G0-C14 analog is a G0-C14 derivative. G0-C14 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles (LNP) .
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- HY-112752
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Liposome
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Others
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Gal-C4-Chol is a glycosylated cholesterol derivative. Gal-C4-Chol can be used as a ligand for asialoglycoprotein receptors (ASGPR) to prepare Galactosylated (Gal) liposomes. Gal-C4-Chol can be used to prepare simple lipid-based nanoparticles .
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- HY-125924
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DSPE-PEG-NH2, MW 2000 ammonium; DSPE-PEG(2000) Amine ammonium
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Liposome
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Others
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DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents .
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- HY-136304
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- HY-112760
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DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium
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Liposome
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Cancer
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18:0 mPEG2000 PE sodium can be used for the preparation of stabilized nucleic acid-lipid particllipid particles (SNALPs). SNALPs represent some of the earliest and best functional siRNA-ABC nanoparticles described .
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- HY-112764
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Liposome
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Metabolic Disease
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DMG-PEG 2000 is used?for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the?lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
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- HY-112764A
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Liposome
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Metabolic Disease
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DMG-PEG Excipient is used?for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG Excipient is also used for the?lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
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- HY-157252
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Liposome
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Cancer
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CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice .
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- HY-139306
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Liposome
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Inflammation/Immunology
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BAMEAO16B is a lipid nanoparticle. BAMEAO16B integrated with disulfide bonds, can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA in response to the reductive intracellular environment for genome editing. BAMEAO16B can be used for the research of gene editing .
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- HY-D0917
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DNA Stain
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Cancer
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TO-PRO 1 is a DNA binding fluorochrome, that atached to the surface of the Feraheme (FH) nanoparticle (NP), to obtain a fluorochrome-functionalized NP. TO-PRO 1 binds DNA through intercalation, and acts as a vital fluorochrome for necrotic cells .
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- HY-151508
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Liposome
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Cancer
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Diamino lipid DAL4 is diamino lipid for the preparation of lipid nanoparticles (LNPs) encapsulated with mRNAs encoding cytokines including IL-12, IL-27 and GM-CSF. Diamino lipid DAL4 delivers mRNA to tumor cells to exert anti-tumor activity .
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- HY-156985
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Isotope-Labeled Compounds
Liposome
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Others
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Lipid AX4 is an ionizable cationic lipid with the pKa of 6.89， and can be used the study for the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo .
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- HY-N6613
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Galacturonic acid polymer
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Others
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Infection
Inflammation/Immunology
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Polygalacturonic acid (Galacturonic acid polymer) is transparent colloid, is a major component of the cell wall. Polygalacturonic acid can be used to prepare silver nanoparticles (AgNPs), as an antioxidant and anti-inflammatory that protect cells from destructive effect of elevated ROS and accelerate wound healing. Polygalacturonic acid nanoparticles also displays anti-bacterial activity .
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- HY-W414069
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Endogenous Metabolite
Liposome
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Others
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Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery .
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- HY-N2362
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DL-2-Aminopropionic acid
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Endogenous Metabolite
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Metabolic Disease
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DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .
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- HY-P10674
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Biochemical Assay Reagents
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Neurological Disease
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QMT-CBT is a near-infrared aggregation-induced luminescent photon. After activation of caspase1 (Cas1), QMT-CBT undergoes a CBT-Cys click reaction to form a cyclic dimer QMT-Dimer (the first aggregate) and assembles into nanoparticles (the second aggregate), turning the AIE signal "on" to enhance imaging of Alzheimer's disease (AD) .
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- HY-160552
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Liposome
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Others
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244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels .
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- HY-P4115
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FABP
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Cancer
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CooP is a linear glioblastoma-targeting nonapeptide. CooP binds to the mammary-derived growth inhibitor/fatty acid binding protein 3 (FABP3) in the glioblastoma cells and its associated vasculature. CooP is used for the targeted delivery of chemotherapy and different nanoparticles .
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- HY-D1540
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Cy 5.5 amine; Lumiprobe Cy 5.5 amine
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Fluorescent Dye
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Others
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Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
|
-
- HY-154974
-
|
|
Liposome
|
Cancer
|
|
LNP Lipid-8 (11-A-M) is an ionizable lipid, which can be used for lipid nanoparticles (LNP) to deliver siRNA to T cells without targeting to ligands. LNP LIPs-8 loaded with GFP siRNA (siGFP), and significantly causes GFP gene silencing in mice model .
|
-
- HY-W145518
-
|
|
Endogenous Metabolite
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Pectin is a heteropolysaccharide, derived from the cell wall of higher plants. Pectin involves in the formation of nanoparticles as a delivery vehicle of agents. Pectin is also an adsorbent, a broad-spectrum antimicrobial agent that binds to bacteria toxins and other irritants in the intestinal mucosa, relieves irritated mucosa .
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-
- HY-172168A
-
|
|
Fluorescent Dye
|
Others
|
|
Orange Fluorescent PLGA nanoparticles, 200nm a nanoparticle made from the polymer PLGA and labeled with an orange fluorescent dye. Orange Fluorescent PLGA nanoparticles, 200nm can be used for drug delivery and for tracing .
|
-
- HY-172174
-
|
|
Fluorescent Dye
|
Others
|
|
Red Fluorescent PLGA nanoparticles, 100nm is a nanoparticle made from the polymer PLGA and labeled with a red fluorescent dye. Red Fluorescent PLGA nanoparticles, 100nm can be used for drug delivery and for tracing .
|
-
- HY-172168B
-
|
|
Fluorescent Dye
|
Others
|
|
Orange Fluorescent PLGA nanoparticles, 500nm a nanoparticle made from the polymer PLGA and labeled with an orange fluorescent dye. Orange Fluorescent PLGA nanoparticles, 500nm can be used for drug delivery and for tracing .
|
-
- HY-172168
-
|
|
Fluorescent Dye
|
Others
|
|
Orange Fluorescent PLGA nanoparticles, 100nm a nanoparticle made from the polymer PLGA and labeled with an orange fluorescent dye. Orange Fluorescent PLGA nanoparticles, 100nm can be used for drug delivery and for tracing .
|
-
- HY-172174B
-
|
|
Fluorescent Dye
|
Others
|
|
Red Fluorescent PLGA nanoparticles, 500nm is a nanoparticle made from the polymer PLGA and labeled with a red fluorescent dye. Red Fluorescent PLGA nanoparticles, 500nm can be used for drug delivery and for tracing .
|
-
- HY-172174A
-
|
|
Fluorescent Dye
|
Others
|
|
Red Fluorescent PLGA nanoparticles, 200nm is a nanoparticle made from the polymer PLGA and labeled with a red fluorescent dye. Red Fluorescent PLGA nanoparticles, 200nm can be used for drug delivery and for tracing .
|
-
- HY-172376
-
-
- HY-168943
-
-
- HY-172376A
-
-
- HY-168943A
-
-
- HY-168943B
-
-
- HY-168943C
-
-
- HY-W011696
-
|
cis-1-Amino-9-octadecene, 80-90%
|
Biochemical Assay Reagents
|
Others
|
|
Oleylamine, 80-90% (cis-1-Amino-9-octadecene, 80-90%) is a long-chain primary alkylamine, which can be used in nanoparticle synthesis as a solvent, surfactant, and reducing agent. Oleylamine, 80-90% forms metastable complexes with metal ions, which can be controllably decomposed to produce nanoparticles. Oleylamine, 80-90% can control the morphology of nanoparticle, prevent the nanoparticle aggregation, and reduce metal precursors to metal nanoparticles .
|
-
- HY-168947A
-
|
|
Fluorescent Dye
|
Others
|
|
Green Fluorescent PLGA nanoparticles, 200nm is a PLGA nanoparticle labeled with a green fluorescent dye and is commonly used in imaging and diagnostic applications.
|
-
- HY-168947B
-
|
|
Fluorescent Dye
|
Others
|
|
Green Fluorescent PLGA nanoparticles, 500nm is a PLGA nanoparticle labeled with a green fluorescent dye and is commonly used in imaging and diagnostic applications.
|
-
- HY-168947
-
|
|
Fluorescent Dye
|
Others
|
|
Green Fluorescent PLGA nanoparticles, 100nm is a PLGA nanoparticle labeled with a green fluorescent dye and is commonly used in imaging and diagnostic applications.
|
-
- HY-147081
-
|
AGRO-100
|
Histone Methyltransferase
Bcl-2 Family
|
Cancer
|
|
AS 1411 (AGRO-100) is an oligonucleotide aptamer targeting nucleoproteins. AS 1411 inhibits tumor cell proliferation by affecting the activity of nucleoprotein-containing complexes and can be used as a carrier to precisely deliver nanoparticles, oligonucleotides and small molecules to cancer cells. AS 1411 reduces PRMT5 expression to inhibit tumor growth in DU145 prostate cancer cells. AS 1411 works by blocking the binding of nucleoproteins to bcl-2 mRNA in MCF-7 breast cancer cells. AS 1411-coupled Jin nanospheres can inhibit breast cancer cell proliferation in vitro and in mouse models, has the ability to cross the blood-brain barrier with low tissue toxicity .
|
-
- HY-D2314
-
|
|
Liposome
|
Others
|
|
Cyanine 7-amine (chloride hydrochloride) can be used to label cationic nanoparticles (NPs) or to NP conjugates (NPCs). It can track the residence time and clearance of nanoparticles in the body .
|
-
- HY-144012A
-
|
16:0 PEG350 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Liposome
|
Others
|
|
DPPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144012B
-
|
16:0 PEG550 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
DPPE-PEG550 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155926
-
|
14:0 PEG750 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
Liposome
|
Others
|
|
DMPE-PEG750 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155931
-
|
DOPE-PEG550; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Liposome
|
Others
|
|
18:1 PEG550 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013H
-
|
DSPE-mPEG5000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Liposome
|
Others
|
|
18:0 mPEG5000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013B
-
|
DSPE-mPEG550 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
18:0 mPEG550 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144012C
-
|
16:0 PEG750 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
DPPE-PEG750 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155924
-
|
14:0 PEG350 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Liposome
|
Others
|
|
DMPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155927
-
|
14:0 PEG1000 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Liposome
|
Others
|
|
DMPE-PEG1000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144012E
-
|
16:0 PEG3000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Liposome
|
Others
|
|
DPPE-PEG3000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013A
-
|
DSPE-mPEG350 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Liposome
|
Others
|
|
18:0 mPEG350 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013D
-
|
DSPE-mPEG1000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Liposome
|
Others
|
|
18:0 mPEG1000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155934
-
|
DOPE-PEG5000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Liposome
|
Others
|
|
18:1 PEG5000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144012D
-
|
16:0 PEG1000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Liposome
|
Others
|
|
DPPE-PEG1000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155933
-
|
DOPE-PEG3000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Liposome
|
Others
|
|
18:1 PEG3000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155932
-
|
DOPE-PEG1000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Liposome
|
Others
|
|
18:1 PEG1000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144012H
-
|
16:0 PEG5000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Liposome
|
Others
|
|
DPPE-PEG5000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155925
-
|
14:0 PEG550 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Liposome
|
Others
|
|
DMPE-PEG550 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013E
-
|
DSPE-mPEG3000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Liposome
|
Others
|
|
18:0 mPEG3000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155930
-
|
DOPE-PEG350; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Liposome
|
Others
|
|
18:1 PEG350 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-144013C
-
|
DSPE-mPEG750 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
18:0 mPEG750 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155929
-
|
14:0 PEG5000 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Liposome
|
Others
|
|
DMPE-PEG5000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-155928
-
|
14:0 PEG3000 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Liposome
|
Others
|
|
DMPE-PEG3000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
-
- HY-W440810
-
|
|
Liposome
|
Others
|
|
Undecyl 6-bromohexanoate can be useful for the preparation of lipid nanoparticles.
|
-
- HY-147332
-
|
|
Liposome
|
Neurological Disease
|
|
TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
|
-
- HY-163044
-
|
|
Liposome
|
Infection
|
|
C12-SPM is a lipid that mediates siRNA delivery. C12-SPM has no significant cytotoxicity and can be used for research on hepatoviral diseases .
|
-
- HY-150115
-
|
|
Liposome
|
Others
|
|
Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-150118
-
|
|
Liposome
|
Others
|
|
Lipid 8 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-150117
-
|
|
Liposome
|
Others
|
|
Lipid 6 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-153378
-
|
|
Liposome
|
Others
|
|
Lipid 15 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-150116
-
|
|
Liposome
|
Others
|
|
Lipid 1 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-134782
-
|
|
Liposome
|
Others
|
|
OF-Deg-Lin is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-153377
-
-
- HY-153373
-
|
|
Liposome
|
Others
|
|
4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).
|
-
- HY-160705
-
|
|
Liposome
|
Cancer
|
|
PNI 132, an ionizable lipid derived from the patent WO2020252589A, is useful in the formulation of lipid nanoparticles.
|
-
- HY-168380
-
-
- HY-142979
-
|
|
Liposome
|
Others
|
|
DSPE-PEG 2000 is a PEG-lipid that can be used to form micelles as nanoparticles for drug delivery .
|
-
- HY-153138
-
-
- HY-169484
-
|
|
Liposome
|
Others
|
|
SIL lipid is the synthetic ionized lipid, and can be used for synthesis of lipid nanoparticles (LNPs) for siRNA delivery .
|
-
- HY-W440813
-
|
|
Liposome
|
Others
|
|
Heptadecan-9-yl 8-bromooctanoate can be useful for the building or modification of lipid nanoparticles.
|
-
- HY-141892A
-
|
DSPE PEG(2000) Carboxylic Acid sodium
|
Liposome
|
Others
|
|
DSPE-PEG Carboxylic acid (sodium), MW 2000 is a PEG-lipid that can be used in the preparation of drug delivery nanoparticles .
|
-
- HY-168374A
-
-
- HY-134780
-
|
|
Liposome
|
Others
|
|
L-369 is an ionizable cationic lipid that can be used to synthesize lipid nanoparticles and deliver mRNA .
|
-
- HY-112755
-
|
|
Liposome
|
Others
|
|
DODMA is a cationic lipid that can be used to prepare lipid nanoparticles. DODMA can be used for drug delivery .
|
-
- HY-160908
-
|
|
Liposome
|
Others
|
Lipid 88 is an ionizable cationic lipid. Lipid 88 can be used to synthesize lipid nanoparticles and deliver mRNA .
|
-
- HY-W800783
-
|
CDESA
|
Liposome
|
Others
|
|
DSTAP chloride (CDESA) is a cationic lipid that used in the formation of lipid nanoparticles (LNPs). DORI chloride has high transfection efficiency .
|
-
- HY-160512
-
|
|
Liposome
|
Others
|
Lipid 9 is an ionizable lipid that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
|
-
- HY-159713
-
|
|
Liposome
|
Others
|
|
Lipid R6 is a lipid molecule that can be used to synthesize liposomes and is the lipid component in lipid nanoparticle (LNP) systems.
|
-
- HY-168775
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Lipid 29d is an unsaturated ionizable cationic lipid that can be utilized in the formation of lipid nanoparticles and the delivery of mRNA .
|
-
- HY-160576
-
|
|
Liposome
|
Cancer
|
|
DNCA is a neutral lipid that can be used in the generation of lipid nanoparticles (LNPs). DNCA can be used in nucleic acid delivery .
|
-
- HY-158082C
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 70000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran, MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye, with the molecular weight of 70 kD. TRITC-dextran, MW 70000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 70000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-158082
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 4000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran MW 4000 (Tetramethyl rhodamine isothiocyanate glucan, MW 4000) is a fluorescent dye, with the molecular weight of 4 kD. TRITC-dextran MW 4000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 4000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 4000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-158082E
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 500000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran, MW 500000 (Tetramethyl rhodamine isothiocyanate glucan, MW 500000) is a fluorescent dye, with the molecular weight of 500 kD. TRITC-dextran, MW 500000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 500000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 500000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-158082A
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 20000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran, MW 20000 (Tetramethyl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-158082B
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 40000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran, MW 40000 (Tetramethyl rhodamine isothiocyanate glucan, MW 40000) is a fluorescent dye, with the molecular weight of 40 kD. TRITC-dextran MW 40000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 40000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 40000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-158082D
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 150000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran, MW 150000 (Tetramethyl rhodamine isothiocyanate glucan, MW 150000) is a fluorescent dye, with the molecular weight of 150 kD. TRITC-dextran, MW 150000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 150000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 150000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-W036410
-
|
3-Aminopropyltrimethoxysilane
|
Biochemical Assay Reagents
|
Others
|
|
Aminopropyltrimethoxysilane (3-Aminopropyltrimethoxysilane) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-158082H
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 2000000
|
Fluorescent Dye
|
Others
|
|
TRITC-dextran, MW 2000000 (Tetramethyl rhodamine isothiocyanate glucan, MW 2000000) is a fluorescent dye, with the molecular weight of 2000 kD. TRITC-dextran, MW 2000000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 2000000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 2000000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-D0356
-
|
|
Fluorescent Dye
|
|
|
Eriochrome Black A is an azo dye that can be removed from water by an adsorbent made of magnetic NiFe2O4 nanoparticles.
|
-
- HY-171306
-
|
|
Liposome
|
Others
|
|
MK16 is a lipid material that can be used to construct blood-brain barrier penetrable lipid nanoparticles for mRNA delivery .
|
-
- HY-139671
-
-
- HY-116210
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Phenylphosphinic acid binds to metal oxide surfaces for a modification and functionalization. Phenylphosphinic acid can also be used for nanoparticles or sol-gel synthesis .
|
-
- HY-170455
-
|
|
Biochemical Assay Reagents
|
Others
|
|
18:1 PE (DOPE) pSar25 is a derivative of polyethylene glycol that can be used for liposomal and lipid nanoparticle delivery systems.
|
-
- HY-168370
-
-
- HY-160578
-
|
N-Cholesteryl succinyl glucosamine
|
Liposome
|
Others
|
|
Glucosamine Cholesterol (N-Cholesteryl succinyl glucosamine) is a glucosamine-based lipid conjugate, and can be used in the formation of lipid nanoparticles (LNPs) .
|
-
- HY-153372
-
|
|
Liposome
|
Others
|
|
93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).
|
-
- HY-153186
-
|
|
Liposome
|
Others
|
|
LNP Lipid-3 is an ionizable lipid extracted from patent WO2021113777A, and can be used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-147172
-
|
|
Fluorescent Dye
|
Others
|
|
Ru(bpy)2(dcbpy)NHS (dihexafluorophosphate) combines with gold nanoparticle amplification can be used for the determination of lysozyme with electrochemiluminescence .
|
-
- HY-170333
-
-
- HY-W344875
-
|
|
Biochemical Assay Reagents
|
|
|
Sodium ligninsulfonate is a natural polymer compound with good surface activity, which can be used as a stabilizer for liposomes, a promoter for nanocrystal production, and a dispersant for nanoparticle preparation.
|
-
- HY-W440931
-
|
|
Liposome
|
Cancer
|
|
MPEG2000-DMG is a synthetic lipid comprised of polyPEG and dimyristoyl glycerol. It is used in the creation of lipid nanoparticles (LNPs) for mRNA vaccines.
|
-
- HY-W590548
-
|
|
Liposome
|
Others
|
|
ATX-001 is an ionizable cationic lipid. ATX-001 can be used in the formation of lipid nanoparticles (LNPs) for the delivery mRNA .
|
-
- HY-W590532
-
|
|
Liposome
|
Others
|
|
306-O12B is an ionizable cationic lipid used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA .
|
-
- HY-W598178
-
|
|
Liposome
|
Others
|
|
93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .
|
-
- HY-W110707
-
|
Hexadecylamine
|
Biochemical Assay Reagents
|
Cancer
|
|
Cetylamine (Hexadecylamine) denatures proteins faster and prevents flocculation. Cetylamine can cap zinc sulfide nanoparticles and is used in cancer research .
|
-
- HY-158867
-
|
|
Liposome
|
Infection
|
|
DOSPA hydrochlorid is a frequently utilized cationic lipid in the generation of Lipid Nanoparticles (LNPs) for the development of mRNA vaccines, including the COVID-19 vaccine.
|
-
- HY-W019831
-
|
Silica; Colloidal anhydrous silica
|
Endogenous Metabolite
|
Others
|
|
Silicon dioxide (Silica) serves as the core of gold-coated silica nanoparticles, featuring a spherical structure enveloped in a layer of gold nanoparticles on its surface. This composition endows them with distinctive chemical and optical properties, rendering them highly desirable for various applications in medicine, batteries, catalysis, sensors, and spectroscopy. The silica component provides a large surface area, a non-porous nature, outstanding charge transport capabilities, and biocompatibility.
|
-
- HY-153235
-
|
|
SARS-CoV
Liposome
|
Infection
|
|
COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing mRNA encoding COVID-19 Spike Protein , suitable for detection of RNA delivery, translation efficiency, cell viability, etc. COVID-19 Spike Protein is the novel coronavirus pneumonia spike protein located on the membrane surface. COVID-19 Spike Protein undertakes the functions of virus binding to host cell membrane receptors and membrane fusion, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design .
|
-
- HY-B1620L
-
|
PVP, average Mw~40000; Polyvidone, average Mw~40000; Povidone, average Mw~40000
|
Biochemical Assay Reagents
|
Others
|
|
Polyvinylpyrrolidone, average Mw~40000 is a multifunctional synthetic polymer with an average molecular weight of 40,000. Polyvinylpyrrolidone is widely used to synthesize nanoparticles .
|
-
- HY-W250183B
-
|
Polyethylene glycol octadecyl ether (n～20)
|
Liposome
|
Others
|
|
Polyoxyethylene (20) stearyl ether (Polyethylene glycol octadecyl ether) is a polyethylene glycolated lipid surfactant that can be used in the formation and stabilization studies of nanoparticles .
|
-
- HY-B1620M
-
|
PVP, average Mw～55000; Polyvidone, average Mw～55000; Povidone, average Mw～55000
|
Biochemical Assay Reagents
|
Others
|
|
Polyvinylpyrrolidone, average Mw～55000 is a multifunctional synthetic polymer with an average molecular weight of 55,000. Polyvinylpyrrolidone is widely used to synthesize nanoparticles .
|
-
- HY-B1620J
-
|
PVP, average Mw～10000; Polyvidone, average Mw～10000; Povidone, average Mw～10000
|
Biochemical Assay Reagents
|
Others
|
|
Polyvinylpyrrolidone, average Mw～10000 is a multifunctional synthetic polymer with an average molecular weight of 10,000. Polyvinylpyrrolidone is widely used to synthesize nanoparticles .
|
-
- HY-B1620N
-
|
PVP, average Mw～360000; Polyvidone, average Mw～360000; Povidone, average Mw～360000
|
Biochemical Assay Reagents
|
Others
|
|
Polyvinylpyrrolidone, average Mw～360000 is a multifunctional synthetic polymer with an average molecular weight of 360,000. Polyvinylpyrrolidone is widely used to synthesize nanoparticles .
|
-
- HY-157524
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1,2-O-Dioctadecyl-sn-glycerol (Compound 7b) is a lipid molecule that can be used to synthesize thermostable lipid nanoparticle .
|
-
- HY-172357
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Poly (3-hydroxybutyric acid-co-3-hydroxyvaleric acid) is a biodegradable polymer that can be used to construct nanoparticles for drug delivery .
|
-
- HY-159735
-
|
|
Liposome
|
Others
|
|
Lipid 23 is an ionizable cationic amino lipid that can be used to generate lipid nanoparticles (LNP). Lipid 23 can be used for mRNA delivery .
|
-
- HY-W440811
-
|
|
Liposome
|
Others
|
|
6-Bromohexyl 2-hexyldecanoate is a lipid. 6-Bromohexyl 2-hexyldecanoate can be used to build lipid nanoparticles and nanomaterials .
|
-
- HY-W590531
-
-
- HY-149167
-
-
- HY-B1620O
-
|
PVP, average Mw~1300000; Polyvidone, average Mw~1300000; Povidone, average Mw~1300000
|
Biochemical Assay Reagents
|
Others
|
|
Polyvinylpyrrolidone, average Mw~1300000 is a multifunctional synthetic polymer with an average molecular weight of 1,300,000. Polyvinylpyrrolidone is widely used to synthesize nanoparticles .
|
-
- HY-19873
-
|
|
Photosensitizer
|
Cancer
|
|
SL-052 is a hypocrellin-based photosensitizer that has recently shown promising results in clinical and preclinical testing for cancer photodynamic therapy (PDT). SL-052 is encapsulated in biodegradable polylactic-co-glycolic acid (PLGA) polymer nanoparticles optimized using single emulsion solvent evaporation technology. The SL-052-PLGA nanoparticles were more effective in PDT treatment of subcutaneous SCCVII squamous cell carcinoma compared to polyvinylpyrrolidone (PVP)-based and standard liposomal SL-052 formulations. A longer time interval between drug injection and tumor illumination can improve tumor cure rates, and SL-052-PLGA nanoparticles showed the best therapeutic effect among all SL-052 formulations.
|
-
- HY-129563
-
|
|
HIV
HIV Protease
|
Infection
|
|
CGP 57813 is a peptidomimetic inhibitor of HIV protease that can be encapsulated by nanoparticles composed of poly(D,L-lactic acid) (PLA) and pH-sensitive methacrylic acid copolymers and delivered into the body .
|
-
- HY-112756
-
|
|
Liposome
|
Others
|
|
PEG2000-DGG is a synthetic lipid. PEG2000-DGG can be used in lipid-based nanoparticle (LNP) delivery systems .
|
-
- HY-153852
-
|
|
Liposome
|
Others
|
|
1LNP Lipid-7 (Compound 7013) is a lipid. LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) and for drug delivery .
|
-
- HY-46759A
-
|
|
Liposome
|
Infection
|
|
Genevant CL1 monohydrochloride is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery .
|
-
- HY-W441012
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-NHS, MW 600 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-149156
-
|
|
Liposome
|
Cancer
|
|
Lipid C24 is a cationic ionizable lipid, and can be used in the formation of lipid nanoparticles (LNPs). Lipid C24 can be used for research of delivery of nucleic acids .
|
-
- HY-W441016
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-NHS, MW 5000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine .
|
-
- HY-W441015A
-
|
|
Liposome
|
Others
|
|
DSPE-m-PEG-NHS (MW 3400) is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-156630
-
|
|
Liposome
|
Others
|
|
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
|
-
- HY-108989
-
|
|
Bacterial
|
Infection
Cancer
|
|
FMDP is an inhibitor of GlcN-6-P Synthase with an anti-candidal activity. FMDP can be covalently attached to a polyethylene glycol as a nanoparticle shows strong anticancer activity .
|
-
- HY-148830
-
|
|
Liposome
|
Others
|
|
Piperazine-bis(ethyl octadeca-9,12-dienoate) is a cationic lipid extracted from patent WO2023036148A1, and can be used for the generation of Lipid nanoparticles (LNPs).
|
-
- HY-156630A
-
|
|
Liposome
|
Others
|
|
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
|
-
- HY-169478
-
|
|
Liposome
|
Cancer
|
|
Lipid N2-3L is an ionizable cationic lipid (pKa = 8.99) that can be used to generate supramolecular lipid nanoparticles (SMLNPs) for mRNA delivery. Lipid nanoparticles formed by encapsulating a luciferase reporter gene with Lipid N2-3L were detected to accumulate in the lymph nodes of mice, indicating that they can effectively enter the mouse immune system. Lipid nanoparticles formed by encapsulating ovalbumin mRNA and the TLR7/8 agonist Resiquimod (HY-13740) with Lipid N2-3L were able to reduce tumor volume and increase survival in the MC-38-OVA mouse colon cancer model. Lipid N2-3L can be used in the research of drug delivery for cancer-related therapies .
|
-
- HY-W591461
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG-COOH, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal carboxylic acid can react with primary amine groups to form a stable amide bond.
|
-
- HY-W441021
-
|
|
Liposome
|
Others
|
|
DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon, and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment.
|
-
- HY-W998658
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY 564/570 is a fluorescent dye that can be used in labeling superparamagnetic nanoparticles (MNPs). BODIPY 564/570 exhibits a maximal excitation wavelength of 564 nm and a maximal emission wavelength of 570 nm .
|
-
- HY-153371
-
|
|
Liposome
|
Others
|
|
50-C2-C9-4tail has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo.
|
-
- HY-W127410
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Hexanoic anhydride is used as a reactant for the synthesis of acremomannolipin A. For the green synthesis of acyclovir dipivoxil (acyclovir proagent), for the preparation of hexanoyl-modified chitosan nanoparticles, chitosan-based polymer surfactants by N-acylation of chitosan .
|
-
- HY-160580
-
|
|
Liposome
|
Others
|
|
G1-OC2-K3-E10 is an ionizable lipid, and can be used for delivery of mRNA in lipid nanoparticles (LNPs) .
|
-
- HY-108932
-
|
Gemcitabine 5′-phosphate
|
Apoptosis
|
Cancer
|
|
Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate has a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles .
|
-
- HY-108932A
-
|
Gemcitabine 5′-phosphate disodium
|
Apoptosis
|
Cancer
|
|
Gemcitabine monophosphate (Gemcitabine 5′-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate has a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles .
|
-
- HY-W010713
-
|
Fimaporfin free base
|
Photosensitizer
|
Cancer
|
|
Meso-tetraphenylchlorin (TPCS2a) is a photosensitizer with poor water solubility, which limits its use in the blood circulation. However, TPCS2a@NPs nanoparticles can be prepared based on polylactic-co-polyethylene glycol acid (PLGA) polymer core loaded with TPCS2. Such nanoparticles can be coated with mesenchymal stem cell-derived plasma membranes (mMSCs) to form mMSC-TPCS2a@NPs, which prolongs blood circulation time and improves tumor targeting ability. Compared with uncoated TPCS2a@NPs, mMSC-TPCS2a@NPs can reduce macrophage uptake by 54% to 70% under different conditions. Both nanoparticle forms are effectively accumulated in MCF7 and MDA-MB-231 breast cancer cells, while uptake in normal breast epithelial cells MCF10A is significantly lower .
|
-
- HY-128720
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Diethyl oxalpropionate is an intermediate for poly((R,S)-3,3-dimethylmalic acid) (PDMMLA) derivative synthesis. PDMMLA derivative can be used in synthesis of nanoparticles and study of warfarin encapsulation and controlled release .
|
-
- HY-W008034
-
|
|
Amino Acid Derivatives
|
Cancer
|
|
Fmoc-L-Trp(Boc)-OH is an amino acid derivative with a protective group, which has the ability to self-assemble and form nanoparticles. Fmoc-L-Trp(Boc)-OH can be used in the study of anticancer drug delivery .
|
-
- HY-160574
-
|
|
Liposome
|
Inflammation/Immunology
Cancer
|
|
CoPoP (cobalt porphyrin-phospholipid) is a palmitic acid (16:1) phosphatidyl choline-cobal porphyrin conjugate. CoPoP formulated into lipid nanoparticles (LNPs) have successfully been used for delivery and imaging applications [1][2].
|
-
- HY-113736
-
|
|
Amino Acid Derivatives
|
Others
|
|
Glycyllysine is a polypeptide that can be used in the synthesis of antibodies and amino acid type gemini surfactants. Glycyllysine has potential applications in modifying plasmid/gemini/lipid (P/G/L) nanoparticles transport carriers .
|
-
- HY-W440995
-
|
|
Liposome
|
Cancer
|
|
DOPE-PEG-Mal (MW 2000) is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. It is also reactive with thiol at pH 6.5 tp 7.5 to form a stable thioether bond.
|
-
- HY-W590555
-
|
|
Liposome
|
Cancer
|
|
Thiol-PEG-DMG, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.
|
-
- HY-W440722
-
|
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
Cholesterol-PEG-Thiol (MW 1000) is a PEGylated lipid that forms micelles in water and can be used to prepare liposomes or nanoparticles as drug delivery systems. The thiol moiety reacts with maleimide to form a stable thioether bond .
|
-
- HY-D1005A23
-
|
PEG-PPG-PEG, 4400 (Averag)
|
Biochemical Assay Reagents
|
Others
|
|
Poloxamer 401 L121 is block polymer of polyoxyethylene and polyoxypropylene. Poloxamer 401 L121 is utilized as lymphotrophic particles in nanoparticle engineering, as inhibitor of multidrug resistance and adjuvant activities or as surfactants and emulsifying agents in cosmetics .
|
-
- HY-W440719
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-MAL (MW 2000) is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.
|
-
- HY-156936
-
|
|
Liposome
|
Others
|
|
RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .
|
-
- HY-112773
-
|
|
Liposome
|
Others
|
|
1,1′,1′′,1′′′-[1,4-Piperazinediylbis(2,1-ethanediylnitrilo)]tetrakis[2-dodecanol] is a lipid/lipidoid used in preparation of lipid-based or lipidoid nanoparticles .
|
-
![1,1′,1′′,1′′′-[1,4-Piperazinediylbis(2,1-ethanediylnitrilo)]tetrakis[2-dodecanol]](//file.medchemexpress.eu/product_pic/hy-112773.gif)
- HY-148049
-
|
|
Liposome
|
Others
|
|
TT3 is an ionizable lipid-like materials for mRNA and CRISPR/Cas9 delivery .
|
-
- HY-W590683
-
|
|
Liposome
CRISPR/Cas9
|
Others
|
|
9A1P9 is a multi-tail ionizable cationic phospholipid. 9A1P9 induces membrane destabilization. 9A1P9 can be used for CRISPR-Cas9 gene editing in mice .
|
-
- HY-W591381
-
|
DSG-PEG 2000
|
Liposome
|
Others
|
|
DSG-PEG is a type of polyethylene glycol grease. DSG-PEG can be used to prepare liposomes .
|
-
- HY-W719862
-
|
|
Liposome
|
Others
|
|
16:0 PDP PE belongs to a class of head group modified functionalized lipids. 16:0 PDP PE has been used in preparation of rhodamine high-density lipoprotein nanoparticle (Rh-HDL NP) synthesis.
|
-
- HY-W440690
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-Amine (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles.
|
-
- HY-153737
-
|
|
Liposome
|
Others
|
|
113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
|
-
- HY-W440724
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-Thiol (MW 3400) is an amphiphatic PEG derivative which forms micelles in water and can be used to prepare liposomes or nanoparticles for drug delivery system. The thiol moiety is reactive with maleimide to form a stable thioether bond.
|
-
- HY-170704
-
|
|
Liposome
|
Metabolic Disease
|
|
DSPE-PEG2000-TCO is a PEGylated derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (HY-112530) that can be used to construct lipid nanoparticles (LNPs) .
|
-
- HY-159866
-
|
mPEG2000-Cholesterol
|
Liposome
|
Others
|
|
mPEG2000-CLS (mPEG2000-Cholesterol) is a PEGylated form of Cholesterol (HY-N0322). mPEG2000-CLS can be used to prepare liposome or nanoparticle .
|
-
- HY-160577
-
|
|
Liposome
|
Others
|
|
DOG-IM4 can be used to synthesize nanoparticles to deliver antigen-encoding nucleic acids. It could be used to try to target autoimmune diseases, rare blood or metabolic diseases, allergies, cancer or infectious diseases .
|
-
- HY-W590681
-
|
|
Liposome
|
Others
|
|
113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
|
-
- HY-W440927
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG-NHS, MW 2,000 is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The NHS ester is reactive with amine to form a stable amide bond. Reagent grade, for research purpose.
|
-
- HY-148855
-
|
|
Liposome
|
Others
|
|
OF-C4-Deg-Lin is an ionizable lipid with varied linker lengths. OF-C4-Deg-Lin can be used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA .
|
-
- HY-W440820
-
|
|
Liposome
|
Cancer
|
|
Bis(bis(2-carboxyethyl)aminopropyl)methylamine is a symmetrical branched linker featuring three tertiary amines and four carboxylic acids. Each carboxylic acid is open to forming esters or amides. It can be used in developing lipid nanoparticles.
|
-
- HY-122787
-
|
|
Others
|
Others
|
|
Tylocrebrine is a compound with anticancer activity. Its clinical research was interrupted due to toxicity issues. By making it into targeted nanoparticles, its inhibitory index can be improved, the killing effect on tumor cells can be enhanced and brain penetration can be reduced.
|
-
- HY-W590679
-
|
|
Liposome
|
Others
|
|
113-O16B is a disulfide bond-containing ionizable cationic lipidoid. 113-O16B has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
|
-
- HY-139305
-
|
|
Liposome
|
Cancer
|
|
CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response .
|
-
- HY-153936
-
|
|
Apoptosis
ROS Kinase
|
Others
|
|
Methyl 12-methyltridecanoate ((R)-betaxolol hydrochloride) is a biosurfactant extracted from Brevibacterium casei LS14.Methyl 12-methyltridecanoate provides a novel approach for functionalizing the silver nanoparticles higher biocompatibility in vivo environmental .
|
-
- HY-107799
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .
|
-
- HY-134781
-
CKK-E12
1 Publications Verification
|
Liposome
|
Others
|
|
CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,
|
-
- HY-159675
-
|
|
Liposome
|
Inflammation/Immunology
|
|
1-A-N is a lipid nanoparticle (LNP) used for in vivo delivery of siRNA. 1-A-N can regulate immune response by delivering siCD45 (siRNA targeting CD45) to T cells and silencing the CD45 gene .
|
-
- HY-W590547
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(6-(4-Hydroxybutylamino)hexyl)carbamic undecyl is a lipid with a terminal hydroxyl group, which is used to construct or modify lipid nanoparticles (LNP). (6-(4-Hydroxybutylamino)hexyl)carbamic undecyl can be used in drug delivery research .
|
-
- HY-W440917
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-FITC, MW 5000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-W440915
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-FITC, MW 2000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-W011607
-
|
|
Amino Acid Derivatives
|
Others
|
|
L-Alanyl-L-tryptophan is a dipeptide formed from L-alanyl and L-tryptophan, and is also a metabolite. L-Alanyl-L-tryptophan can be adsorbated on the surface of gold nanoparticles, and the Raman signal can be enhanced by SERS technology to obtain the enhanced Raman spectroscopy .
|
-
- HY-W013122
-
|
Cholesteryl butyrate
|
Biochemical Assay Reagents
|
Cancer
|
|
Cholesteryl n-butyrate is a cholesterol ester composed of cholesterol and butyrate, two naturally occurring substances. Cholesteryl n-butyrate can be used to synthesize solid lipid nanoparticles (SLNs) with inhibitory activity on the adhesion and migration of colon cancer cells, providing a delivery system for the anticancer drug butyrate .
|
-
- HY-W440916
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-FITC, MW 3400 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
-
- HY-W800825
-
|
|
Liposome
|
Cancer
|
|
Octadecanedioic Acid Mono-L-carnitine ester is a cationic lipid which may be used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Its terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.
|
-
- HY-171019
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Lipid 119-23 is an ionizable cationic lipid which can be utilized in the formation of lipid nanoparticles and the delivery of mRNA. Lipid 119-23 exhibits an enhanced capability to express functional mCre in several categories of immune cells, spanning the liver, spleen and lung .
|
-
- HY-168776
-
|
|
Biochemical Assay Reagents
|
Others
|
|
(S)-C12-200 is the (S)-isomer of C12-200 (HY-145405), an ionizable cationic lipid and helper lipid. (S)-C12-200 can be utilized in the formation of lipid nanoparticles and mRNA delivery .
|
-
- HY-141629S1
-
-
- HY-154971
-
|
|
Apoptosis
|
Cancer
|
|
Ara-SH is a Cytarabine mercaptopropionic acid-substituted derivative. Ara-SH is used as the trigger to fabricate a smart Cytarabine and Venetoclax-coloaded nanoparticle (AV-NP) through self-assembly. Ara-SH exhibits remarkable synergistic antileukemia effects in vitro and in vivo .
|
-
- HY-Y0623
-
|
HOSu; 1-Hydroxy-2,5-pyrrolidinedione
|
Biochemical Assay Reagents
|
Others
|
|
N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is an activated ester commonly used in bioconjugation technologies such as protein labeling with fluorescent dyes and enzymes, chromatography supports, beads, nanoparticles, and microarrays Surface activation of glass slides, and chemically synthesized peptides .
|
-
- HY-W073196
-
|
Tetrachloroauric(Ⅲ) acid hydrate (48% Au basis)
|
Biochemical Assay Reagents
|
Others
|
|
Gold(Ⅲ) chloride hydrate (48% Au basis) (Tetrachloroauric(Ⅲ) acid hydrate (48% Au basis)) can be used to prepare gold nanoparticles. Gold(Ⅲ) chloride hydrate (48% Au basis) is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-N2362R
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Cucurbitacin IIb (Standard) is the analytical standard of Cucurbitacin IIb. This product is intended for research and analytical applications. Cucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti-inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB (p65), blocks nuclear translocation of NF-κB (p65) and decreases mRNA levels of IκBα and TNF-α .
|
-
- HY-155788
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-DBCO ammonium is the ammonium salt form of DSPE-PEG-DBCO. DSPE-PEG-DBCO ammonium is utilized in copper-free click chemistry through SPAAC conjugation with an azido-functionalized peptide ligand. DSPE-PEG-DBCO ammonium is applied in drug-delivery and nanoparticle research .
|
-
- HY-168399
-
|
|
Liposome
|
Cancer
|
|
PEG(2000)-C-DMG is a PEGylated derivative of 1,2-Dimyristoyl-sn-glycerol (HY-128468). PEG(2000)-C-DMG can be used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of siRNA .
|
-
- HY-W440921
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Rhodamine, MW 5000 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-142981
-
|
DODA
|
Liposome
|
Others
|
|
Dioctadecylamine (DODA) is a secondary amine that has been shown to self-organize in plate-like structures in aqueous solution. Dioctadecylamine exhibits sufficiently hydrophobic properties of nanoparticles and good dispersibility in nonpolar solvent. Dioctadecylamine does not form a monolayer above pH 3.9 .
|
-
- HY-W440906
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-Vinylsulfone, MW 3400 is a thiol reactive PEG lipid. The polymer can self-assemble spontaneously in aqueous solution to form lipid bilayer and be used to prepare nanoparticles/liposomes for drug delivery, for example mRNA vaccine or DNA vaccine. Reagent grade, for research use only.
|
-
- HY-W440920
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Rhodamine, MW 3400 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
|
-
- HY-W075770
-
|
Nickel monoxide
|
Bacterial
Reactive Oxygen Species
|
Infection
Metabolic Disease
Cancer
|
|
Nickel(II) oxide is a chemical compound which nanoparticle form (NiO NPs) exhibits antibacterial, antifungal, antileishmanial, anti-diabetic and anticancer activities. NiO NPs can be activated by ultraviolet and visible light to generate reactive oxygen species, which may be the main cause for the antimicrobial potential .
|
-
- HY-W440891
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-OH, MW 1000 is a hydroxyl terminated phospholipid PEG polymer. The hydrophobic tails allow for the encapsulation and congregation of other hydrophobic drugs. The polymer can be used to prepare liposomes or lipid nanoparticles. Hydroxyl terminal can further derivatize the compound. Reagent grade, for research use only.
|
-
- HY-148702
-
|
|
Liposome
|
Cancer
|
|
di-Pal-MTO is a palm oil-based lipid produced by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity .
|
-
- HY-W073196A
-
|
Tetrachloroauric(Ⅲ) acid hydrate (50% Au basis)
|
Biochemical Assay Reagents
|
Others
|
|
Gold(Ⅲ) chloride hydrate (50% Au basis) (Tetrachloroauric(Ⅲ) acid hydrate (50% Au basis)) is an organic intermediate that can be used to prepare gold nanoparticles. Gold(Ⅲ) chloride hydrate (50% Au basis) is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-W073196B
-
|
Tetrachloroauric(Ⅲ) acid hydrate (52% Au basis)
|
Biochemical Assay Reagents
|
Others
|
|
Gold(Ⅲ) chloride hydrate (52% Au basis) (Tetrachloroauric(Ⅲ) acid hydrate (52% Au basis)) is an organic intermediate that can be used to prepare gold nanoparticles. Gold(Ⅲ) chloride hydrate (52% Au basis) is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-D2429
-
|
|
Fluorescent Dye
|
Others
|
|
Dextran-PEG-Cy3 is the Cy3 (HY-D0822)-labeled Dextran-PEG conjugate. Dextran-PEG is used as polymer-polymer systems for the high biocompatibility to maintain cell osmolarity. Dextran-PEG coatings can reduce nanoparticle cytotoxicity .
|
-
- HY-153136
-
|
|
Liposome
|
Others
|
|
LNP Lipid-1 (Method B) is a lipid compound. LNP Lipid-1 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-1 has potential applications in the transport of biologically active substances such as small molecule agents, proteins, and nucleic acids .
|
-
- HY-P10052
-
|
|
VEGFR
|
Cancer
|
|
CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is modified with a nearinfrared cyanine dye bearing an alkyne function, allowing both “click” coupling on azido-modified nanoparticles and fluorescence labelling .
|
-
- HY-W440910
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Cy3, MW 5000 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440909
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Cy3, MW 3400 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-148701
-
|
|
Liposome
|
Cancer
|
|
mono-Pal-MTO is a palm oil-based lipid produced by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity .
|
-
- HY-W440834
-
|
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
DSPE-PEG-Azide, MW 5000 is a click chemistry reactive phospholipid polyPEG which forms lipid bilayer or micelles in an aqueous solution. The polymer can be used to prepare liposomes or nanoparticles used for delivering nutrients or therapeutic agents, for example mRNA or DNA vaccine. Reagent grade, for research use only.
|
-
- HY-W440706
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-alcohol (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.
|
-
- HY-151506
-
|
|
Liposome
|
Cancer
|
|
Phospholipid PL1 is a phospholipid-derived nanoparticle, can deliver costimulatory receptor mRNA (CD137 or OX40) to T cells. Phospholipid PL1 could induce the activation of various immune cells, including T cells and dendritic cells (DCs) in order to boost antitumor immunity .
|
-
- HY-W440913
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Cy5, MW 5000 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440912
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Cy5, MW 3400 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440681
-
|
|
Liposome
|
Others
|
|
C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-W440684
-
|
|
Liposome
|
Others
|
|
C13-113-tetra tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tetra tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-W440683
-
|
|
Liposome
|
Others
|
|
C13-112-tetra-tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tetra-tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-152229
-
|
|
Liposome
|
Cancer
|
|
G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery .
|
-
- HY-141629S2
-
|
Sphingomyelin 16:0-d9
|
Isotope-Labeled Compounds
Liposome
Endogenous Metabolite
|
Others
|
|
N-Palmitoyl-D-sphingomyelin-d9 (Sphingomyelin 16:0-d9) is deuterium labeled N-Palmitoyl-D-sphingomyelin. N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles .
|
-
- HY-P10796
-
|
|
MAPKAPK2 (MK2)
|
Inflammation/Immunology
|
|
YARA peptide, a cell-penetrating peptide, is a MK2 inhibitor. YARA-loaded nanoparticles decreases the levels of inflammatory cytokines (IL-1β, IL-6, and TNF-α) in an ex vivo skin culture model. YARA peptide is promising for research of atopic dermatitis (AD) .
|
-
- HY-W440682
-
|
|
Liposome
|
Others
|
|
C13-113-tri tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tri tail can be formulated into a lipid nanoparticle (LNP).
|
-
- HY-W583869
-
|
1-Stearoyl-2-Oleoyl-sn-glycero-3-PE; 18:0-18:1 PE; PE(18:0/18:1)
|
Liposome
|
Metabolic Disease
|
|
1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipids that contains stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for in vitro delivery of mRNA or nuclear-targeted plasmid DNA.
|
-
- HY-D1600
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cyanine5.5 maleimide potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .
|
-
- HY-W440823B
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG(2000)-amine is a PEGylated derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (HY-112530). DSPE-PEG(2000)-amine can be used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents .
|
-
- HY-W440991
-
|
|
Liposome
|
Cancer
|
|
DOPE-PEG-Amine (MW 2000) is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring.
|
-
- HY-W440949
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Azide-PEG-Silane, MW 2000 is a click reagent which can react with a terminal alkyne via CuAAC or with a cyclooctyne (DBCO/BCN) via SPAAC to form a triazole bond. Silane is a surface modification moiety which can react with hydroxyl group of surface, such as glass, nanoparticles, etc. Reagent grade, for research use only.
|
-
- HY-W440694
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG-Azide (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. Cholesterol-PEG-Azide (MW 2000) can be reacted with alkyne via CuAAC or SPAAC click chemistry.
|
-
- HY-W440936
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG-Rhodamine, MW 5000 is a fatty acid containing PEG polymer which can self assemble in an aqueous solution to form micelles. The polymer can be used to prepare nanoparticles for drug encapsulation. The red dye rhodamine can be easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
|
-
- HY-W440935
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG-Rhodamine, MW 3400 is a fatty acid containing PEG polymer which can self assemble in an aqueous solution to form micelles. The polymer can be used to prepare nanoparticles for drug encapsulation. The red dye rhodamine can be easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
|
-
- HY-W073183
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Dibenzo-24-crown-8-ether is a phase transfer catalyst that can reduce H 2PtCl 6·6H 2O and FeCl 2·4H 2O in a thermal system to synthesize 17 nm monodispersed iron-platinum (FePt) alloy nanoparticles .
|
-
- HY-W011060
-
|
4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane
|
Biochemical Assay Reagents
|
Others
|
|
Cryptand 2.2.2 is a metal ion chelator that can be used as a reducing agent and stabilizer to prepare nanoparticles. At room temperature, Cryptand 2.2.2 can serve as a host molecule, using the chelation effect to selectively bind desired ions (such as Zn 2+, Co 2+, Ni 2+, Cu 2+) .
|
-
- HY-W441002R
-
|
|
Liposome
|
Others
|
|
Taurine (Standard) is the analytical standard of Taurine. This product is intended for research and analytical applications. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes .
|
-
- HY-145411
-
|
|
Liposome
|
Endocrinology
|
|
PEG2000-C-DMG, a pegylated lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3′ untranslated region of transthyretin mRNA .
|
-
- HY-P1116A
-
|
|
Bacterial
|
Infection
Inflammation/Immunology
|
|
PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1 . PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects .
|
-
- HY-P2299
-
|
|
HPV
|
Cancer
|
|
Protein E7(43-62) is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein) .
|
-
- HY-P2299A
-
|
|
HPV
|
Cancer
|
|
Protein E7(43-62) TFA is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein) .
|
-
- HY-W440953
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Stearic acid-PEG-CH2CO2H, MW 1000 is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The terminal carboxyl can react with amine via condensation reaction in the presence of HATU/EDC activator. Reagent grade, for research use only.
|
-
- HY-D2526
-
|
|
Fluorescent Dye
Liposome
|
Others
|
|
Cy3 IRGD-PEG-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy3 IRGD-PEG-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-164720
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-OH (MW 4000) is a hydroxy-terminated phospholipid PEG polymer. The hydrophobic tails that allows the encapsulation and aggregation of other hydrophobic drugs, and the hydroxy-terminated can be further reacted. DSPE-PEG-OH (MW 4000) can prepare liposomes or lipid nanoparticles, which can be used in drug delivery and promoting drug absorption research .
|
-
- HY-130407
-
|
|
PROTAC Linkers
|
Cancer
|
|
Lipoamido-PEG3-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG3-OH (compound TA-TEG-G2CN) can be used in the formation of a highly stable, dendronized gold nanoparticle (AuNP)-based drug delivery platform .
|
-
- HY-W440938
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG-FITC, MW 2000 is an amphiphatic polyPEG which can self assemble to form micelles in water. The polymer can be used to encapsulate therapeutic agent. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
-
- HY-160554
-
|
|
Liposome
|
Infection
Inflammation/Immunology
|
|
C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. C12-113 can also be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice .
|
-
- HY-164723
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-OH (MW 10000) is a hydroxy-terminated phospholipid PEG polymer. The hydrophobic tails that allows the encapsulation and aggregation of other hydrophobic drugs, and the hydroxy-terminated can be further reacted. DSPE-PEG-OH (MW 10000) can prepare liposomes or lipid nanoparticles, which can be used in drug delivery and promoting drug absorption research .
|
-
- HY-164721
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-OH (MW 6000) is a hydroxy-terminated phospholipid PEG polymer. The hydrophobic tails that allows the encapsulation and aggregation of other hydrophobic drugs, and the hydroxy-terminated can be further reacted. DSPE-PEG-OH (MW 6000) can prepare liposomes or lipid nanoparticles, which can be used in drug delivery and promoting drug absorption research .
|
-
- HY-164722
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-OH (MW 8000) is a hydroxy-terminated phospholipid PEG polymer. The hydrophobic tails that allows the encapsulation and aggregation of other hydrophobic drugs, and the hydroxy-terminated can be further reacted. DSPE-PEG-OH (MW 8000) can prepare liposomes or lipid nanoparticles, which can be used in drug delivery and promoting drug absorption research .
|
-
- HY-148842
-
|
|
Liposome
|
Others
|
|
C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity .
|
-
- HY-W440939
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG-FITC, MW 3400 is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
-
- HY-W591332
-
|
|
Liposome
|
Cancer
|
|
DMPE-mPEG, MW 2000 is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the other end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications.
|
-
- HY-W440940
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG-FITC, MW 5000 is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
-
- HY-W440884
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-Ald, MW 3400 is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-132141
-
|
5-Propargylamino-dUTP
|
DNA/RNA Synthesis
|
Others
|
|
5-PA-dUTP (5-Propargylamino-dUTP) is a C5-modified nucleotide and can be incorporated into DNA nanoparticles (DNPs) for photosensitizer delivery . 5-PA-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-P10680
-
|
|
Liposome
|
Others
|
|
TFE-IDAtp1-LinA is a highly potent amphiphilic carrier, containing a trifluoroethyl-iminodiacetic acid analog of Stp. TFE-IDAtp1-LinA, formed nanoparticles with Cas9 RNP/ssDNA, achieved enhanced green fluorescent protein knockouts with an ED50 of 0.38 nM Cas9/sgRNA ribonucleoproteins (RNP) .
|
-
- HY-D2517
-
|
|
Fluorescent Dye
Liposome
|
Others
|
|
Cy3-PEG-DSPE (MW 5000) is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling. Cy3-PEG-DSPE (MW 5000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-W440833
-
|
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
DSPE-PEG-Azide, MW 3400 is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond. Reagent grade, for research use only.
|
-
- HY-158861
-
|
G1-nPr-C14E
|
Liposome
|
Others
|
|
C3-K2-E14 is a multi-ionizable amino-lipid featuring a central tertiary amine with two identical branches and an n-propyl group. Each branch features a propanamide linking to a branched amine, each with two C14 arms and a hydroxyl. Ionizable lipids such as this may be applied in the development of lipid nanoparticles for drug discovery.
|
-
- HY-159702
-
|
|
Mucin
|
Others
|
|
Eudragit RS 100 is a mucoadhesive, nonbiodegradable positively charged polymer,which can be used for research of developing nanoparticles (NPs) for the ophthalmic and oral administration of Ibuprofen (HY-78131) and Cyclosporins (HY-100731), as well as nano- and micro-fibres used as scaffolds. Eudragit RS 100 NPs interacts efficiently with mucin and promotes glutathione (GSH) transmucosal absorption .
|
-
- HY-147112
-
-
- HY-145405
-
|
|
Liposome
|
Others
|
|
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
|
-
- HY-160269
-
|
|
Fluorescent Dye
|
Others
|
|
DSPE-PEG-Fluor 488,MW 2000 is a PEG-dye-lipid conjugate consisting of a DSPE phospholipid and a Fluor 488 dye. DSPE is a phospholipid that spontaneously forms micelles in a water medium, and Fluor 488 is a cyanine dye that is widely used in fluorescence microscopy. Fluor 488 has excitation and emission maxima at 499 nm and 520 nm. Polyethylene glycol lipids are commonly used for the stabilization of lipid nanoparticles .
|
-
- HY-D2544
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG-DSPE (MW 5000) is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG-DSPE (MW 5000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2542
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG-DSPE (MW 2000) is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG-DSPE (MW 2000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-Y1365
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
Cancer
|
|
Gelatins is a non-toxic, non carcinogenic, biodegradable, and non irritating natural polymer derived from partial hydrolysis of collagen. Due to its strong liquid absorption and swelling ability, Gelatins has excellent hemostatic properties and can be used as a matrix material for the reduction, growth, and stability of metal nanoparticles. Gelatins can also be used for tumor cell culture and tumor therapy [1][2][3].
|
-
- HY-D0153
-
|
|
Fluorescent Dye
|
Cancer
|
|
Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL). Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly(lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles .
|
-
- HY-153231
-
|
|
Fluorescent Dye
Liposome
|
Others
|
|
eGFP mRNA-LNP is a lipid nanoparticle (LNP) containing eGFP mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .
|
-
- HY-D2541
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG-DSPE (MW 1000) is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG-DSPE (MW 1000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2516
-
|
|
Fluorescent Dye
Liposome
|
Others
|
|
Cy3-PEG-DSPE (MW 3400) is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy3-PEG-DSPE (MW 3400) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-159176
-
|
|
Cytochrome P450
|
Cancer
|
|
Antitumor agent-183 (compound 3f) has antitumor activity with metabolic stability. Antitumor agent-183 inhibits cancer cell growth, with IC50s less than 5 nM for A549, HCT116, and HS578T cells. The albumin-bound nanoparticle formulation of Antitumor agent-183 has prolonged retention in the tumor tissues .
|
-
- HY-153232
-
|
|
Fluorescent Dye
Liposome
|
Others
|
|
eGFP circRNA-LNP is a lipid nanoparticle (LNP) containing eGFP circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .
|
-
- HY-D2543
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG-DSPE (MW 3400) is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG-DSPE (MW 3400) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-137500
-
|
|
Liposome
|
Neurological Disease
|
|
NT1-014B is a potent NT1-lipidoid encapsulated AmB (amphotericin B). NT1-014B dopes the NT-lipidoids into BBB-impermeable lipid nanoparticles (LNPs) gave the LNPs the ability to cross the BBB. NT1-014B enhances brain delivery through intravenous injection .
|
-
- HY-D0897
-
|
N-(1-Naphthyl)-3-aminopropanesulfonic acid sodium
|
Biochemical Assay Reagents
|
Others
|
|
3-(1-naphthalenylamino)-1-Propanesulfonic acid sodium salt is a compound belonging to the class of sulfonic acids. It is commonly used in the pharmaceutical industry as a buffer and stabilizer for drugs and other medicines. 3-(1-naphthalenylamino)-1-Propanesulfonic acid sodium salt helps to maintain the pH and stability of the drug, thereby improving the efficacy and shelf life of the drug. It can also be used as a dispersant in the production of nanoparticles and other materials.
|
-
- HY-D2545
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG-DSPE (MW 10000) is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG-DSPE (MW 10000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-159700
-
|
|
Liposome
|
Infection
|
|
AA3-DLin is an ionizable cationic lipid with a pKa value of 5.8. AA3-DLin is used to delivery mRNA combined with lipid nanoparticles (LNPs). AA3-DLin LNP COVID-19 vaccines encapsulating SARS CoV-2 spike mRNAs successfully induces strong immunogenicity in a BALB/c mouse model .
|
-
- HY-W440903
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
-
- HY-112758
-
|
|
Liposome
|
Others
|
|
DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies .
|
-
- HY-113217
-
|
|
Liposome
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .
|
-
- HY-167819
-
|
|
Biochemical Assay Reagents
|
|
|
D-Erythro-sphingosyl phosphoinositol is a lipid nanoparticle covalently linked to an antibody with potential activity in targeted compound delivery. D-Erythro-sphingosyl phosphoinositol can enhance the accumulation of compounds in specific cell types. D-Erythro-sphingosyl phosphoinositol may be used as a ligand to enhance the effect of antibodies in immunosuppression. D-Erythro-sphingosyl phosphoinositol can also be used to study the mechanisms related to cell signaling and lipid metabolism.
|
-
- HY-W440926
-
|
|
Biochemical Assay Reagents
Liposome
|
Others
|
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
-
- HY-D2567
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-DSPE (MW 5000) is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG-DSPE (MW 5000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2566
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-DSPE (MW 3400) is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG-DSPE (MW 3400) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2565
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-DSPE (MW 2000) is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG-DSPE (MW 2000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2564
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-DSPE (MW 1000) is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG-DSPE (MW 1000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2568
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG-DSPE (MW 10000) is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG-DSPE (MW 10000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-153231A
-
|
|
Fluorescent Dye
Liposome
|
Others
|
|
eGFP mRNA-LNP (500ng/uL) is a lipid nanoparticle (LNP) containing eGFP mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .
|
-
- HY-112624C
-
|
|
Biochemical Assay Reagents
Endogenous Metabolite
|
Others
|
|
Dextran (MW 40000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds. Dextran has excellent solubility in water, making it useful as a viscosity modifier or stabilizer in foods, paints and adhesives. In the biomedical field, dextran is often used as a plasma expander because of its ability to increase blood volume when administered intravenously. It can also be modified to create dextran-based drug delivery systems, such as targeted nanoparticles.
|
-
- HY-112624B
-
|
Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)
|
Biochemical Assay Reagents
|
Others
|
|
Dextran T70 (MW 70,000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds. Dextran has excellent solubility in water, making it useful as a viscosity modifier or stabilizer in foods, paints and adhesives. In the biomedical field, dextran is often used as a plasma expander because of its ability to increase blood volume when administered intravenously. It can also be modified to create dextran-based drug delivery systems, such as targeted nanoparticles.
|
-
- HY-P10793
-
|
|
EGFR
Apoptosis
|
Cancer
|
|
Cyclic(YCDGFYACYMDV) is a HER2 signaling pathway inhibitor with anti-cancer activity. This compound self-assembles into nanoparticles in aqueous solution and transforms into nanofibers upon specific binding to HER2 on cancer cells. This transformation disrupts HER2 dimerization and subsequent downstream signaling events, leading to cancer cell apoptosis (Apoptosis). The inhibitory effects on HER2 positive breast cancer have been demonstrated to be effective in a murine xenograft model .
|
-
- HY-W440832
-
|
DSPE-PEG(2000) Azide
|
Liposome
|
Infection
|
|
DSPE-PEG-Azide (MW 2000) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery . DSPE-PEG-Azide (MW 2000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-W440885
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-Ald, MW 5000 is a phospholipid PEG polymer which can self-assemble spontaneously in water with their hydrophilic heads oriented toward the water (micelles). The polymer can be used to prepare liposome as a drug nanocarrier for administration of nutrients and therapeutic drugs, such as lipid nanoparticles in mRNA or DNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-145799
-
|
|
Liposome
|
Cancer
|
|
5A2-SC8 is an ionizable amino lipid in lipid nanoparticles (LNPs) that shows high delivery potential and low in vivo toxicity, enabling efficient delivery of small RNAs such as siRNA and miRNA into tumor cells. 5A2-SC8 LNPs can confer a unique delivery fate of RNA within the liver, thereby changing the therapeutic outcomes in cancer models .
|
-
- HY-153229
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing Firefly luciferase mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. Luciferase is commonly used as a bioluminescent reporter gene for gene regulation and function studies. Firefly Luciferase mRNA will express firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Common luciferase are firefly luciferase and sea kidney luciferase .
|
-
- HY-113217S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Cholesteryl oleate-d7 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .
|
-
- HY-D0948
-
|
|
Fluorescent Dye
|
Infection
|
|
Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO2 nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .
|
-
- HY-153230
-
|
|
Liposome
Biochemical Assay Reagents
|
Others
|
|
Firefly luciferase circRNA-LNP is a lipid nanoparticle (LNP) containing Firefly luciferase circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. Luciferase is commonly used as a bioluminescent reporter gene for gene regulation and function studies. Firefly Luciferase circRNA will express firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Common luciferase are firefly luciferase and sea kidney luciferase .
|
-
- HY-W011060R
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cryptand 2.2.2 (Standard) is the analytical standard of Cryptand 2.2.2. This product is intended for research and analytical applications. Cryptand 2.2.2 is a metal ion chelator that can be used as a reducing agent and stabilizer to prepare nanoparticles. At room temperature, Cryptand 2.2.2 can serve as a host molecule, using the chelation effect to selectively bind desired ions (such as Zn2+, Co2+, Ni2+, Cu2+) .
|
-
- HY-E70311
-
|
Thermomyces lanuginosus lipase
|
Endogenous Metabolite
|
Others
|
|
TLL-10X (Thermomyces lanuginosus lipase) is a high-efficiency biocatalyst, a lipase from Thermomyces lanuginosus. TLL-10X can be conjugated to magnetic nanoparticles and coupled to the surface of Fe(3)O(4)-COOH to obtain better temperature resistance and pH resistance. The activity unit (U) of lipase is defined as the amount of enzyme that produces 1 μmol of fatty acid per minute under experimental conditions .
|
-
- HY-N2894
-
|
|
Parasite
|
Infection
|
|
Piperolactam A is a natural product that can be isolated from root of Piper betle. Piperolactam A exhibits promising leishmanicidal action against wild type and drug resistant strains of Leishmania donovani .
|
-
- HY-116282D
-
|
DSS (MW 450000-550000); DXS (MW 450000-550000)
|
HIV
Influenza Virus
|
Others
|
|
Dextran sulfate sodium salt (DSS) (MW 450000-550000) is a polymer of dehydrated glucose with a molecular weight of approximately 450000-550000. DSS with different molecular weights exhibits different biological activities. Dextran sulfate sodium salt (MW 450000-550000) inhibits replication of HIV-1 and influenza A virus. Dextran sulfate sodium salt (MW 450000-550000) can be formulated as nanoparticles and shows antibacterial activity. Dextran sulfate sodium salt (MW 450000-550000) can be used for functional material preparation .
|
-
- HY-113217S1
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Cholesteryl oleate-d7-1 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .
|
-
- HY-162828
-
|
|
STAT
HDAC
|
Cancer
|
|
STAT3/HDAC-IN-2 (compound 18) is a dual inhibitor of STAT3 and HDAC, inducing autophagy and apoptosis. STAT3/HDAC-IN-2 is an amphiphilic hydroxamic acid hybrid based on the natural product isopropanol lactone (IAL) and is a nanoscale anticancer agent. STAT3/HDAC-IN-2 can self-assemble in water to form nanoparticles, which have higher tumor tissue accumulation, cellular uptake and anticancer properties compared to the free state .
|
-
- HY-137499
-
|
|
Liposome
Endogenous Metabolite
|
Neurological Disease
|
|
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
|
-
- HY-131119
-
|
Dioctadecyldimethylammonium bromide; DODAB
|
Liposome
|
Others
|
|
Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.
|
-
- HY-W010572
-
|
alpha-Thioglycerol
|
Biochemical Assay Reagents
|
Others
|
|
1-Thioglycerol, commonly used as a reducing agent in various biochemical and biophysical applications, especially in protein chemistry and molecular biology, it can protect proteins from oxidation and denaturation, and can reduce disulfide bonds to thiols base, which can then be modified or analyzed. In addition, 1-Thioglycerol has been investigated for potential medical applications, including as an inhibitor of cystic fibrosis, which may help improve the function of lung cells, and has also been studied for Used in the preparation of metal nanoparticles and as a stabilizer for certain pharmaceutical preparations.
|
-
- HY-148775B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 40:60) is a kind of poly(lactide-co-glycolide)-block-poly(ethylene glycol) (PLGA-PEG-Mal) nanoparticles. PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 40:60) has a molecular weight of 60kDA to 3.4kDA and contains a 75:25 ratio of lactic acid (LA) to glycolic acid (GA) molecules .
|
-
- HY-148775
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLGA-PEG-MAL (60kDA-3.4kDA, LA:GA ratio 75:25) is a kind of poly(lactide-co-glycolide)-block-poly(ethylene glycol) (PLGA-PEG-Mal) nanoparticles. PLGA-PEG-MAL (60kDA-3.4kDA, LA:GA ratio 75:25) has a molecular weight of 60kDA to 3.4kDA and contains a 75:25 ratio of lactic acid (LA) to glycolic acid (GA) molecules .
|
-
- HY-W040193S
-
|
1,2-Distearoyl-sn-glycero-3-PC-d70; DSPC-d70
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70 is the deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].
|
-
- HY-W040193S3
-
|
1,2-Distearoyl-sn-glycero-3-PC-d83; DSPC-d83
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d83 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].
|
-
- HY-N2362S2
-
|
DL-2-Aminopropionic acid-d3
|
Endogenous Metabolite
|
Metabolic Disease
|
|
DL-Alanine-d3 is the deuterium labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].
|
-
- HY-W250187
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DDMAB, or didodecyldimethylammonium bromide, is a cationic surfactant commonly used in a variety of industrial and research applications. It belongs to the family of quaternary ammonium compounds and has a positively charged head and a hydrophobic tail, which allows it to be used as a detergent, emulsifier and antimicrobial. Known for its ability to disrupt cell membranes, DDMAB is commonly used in microbiology to selectively isolate and identify bacteria. It is also used in nanotechnology to synthesize metal nanoparticles and other materials. In addition, DDMAB has the ability to interact with and penetrate cell membranes, which has potential applications in drug delivery, gene therapy, and other medical fields.
|
-
- HY-W013989
-
|
|
Epoxide Hydrolase
|
Cardiovascular Disease
|
|
1,3-Dicyclohexylurea (DCU) is an orally active and potent sEH (soluble epoxide hydrolase) inhibitor. Oral Delivery of 1,3-Dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive Rats .
|
-
- HY-N2362S
-
|
DL-2-Aminopropionic acid-13C-1
|
Endogenous Metabolite
|
Metabolic Disease
|
|
DL-Alanine- 13C-1 is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].
|
-
- HY-N2362S1
-
|
DL-2-Aminopropionic acid-13C-3
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
DL-Alanine- 13C-3 is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].
|
-
- HY-W250308
-
|
Epsilon-polylysine (MW 3800-4200); ε-Polylysine (MW 3800-4200); ε-PL (MW 3800-4200)
|
Bacterial
|
Others
|
|
Epsilon-polylysine is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine is also used as a liposome stabilizer .
|
-
- HY-N2362S5
-
|
DL-2-Aminopropionic acid-15N
|
Endogenous Metabolite
|
Metabolic Disease
|
|
DL-Alanine- 15N is the 15N labeled DL-Alanine[1]. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[2][3][4][5][6][7].
|
-
- HY-153233
-
|
|
CD19
Liposome
|
Inflammation/Immunology
Cancer
|
|
CD19 car mRNA (Mouse)-LNP is a lipid nanoparticle (LNP) containing CD19 car mRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car mRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .
|
-
- HY-148776
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 50:50) is a kind of poly(lactide-co-glycolide)-block-poly(ethylene glycol) (PLGA-PEG-Mal) nanoparticles. PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 50:50) has a molecular weight of 20kDA to 5.0kDA and contains a 50:50 ratio of lactic acid (LA) to glycolic acid (GA) molecules. The molecular ratio of LA to GA determines the rate of matrix degradation and protein re-release .
|
-
- HY-W250308A
-
|
Epsilon-polylysine (hydrochloride) (MV 2000-5000); ε-Polylysine (hydrochloride) (MV 2000-5000); ε-PL (hydrochloride) (MV 2000-5000)
|
Bacterial
|
Infection
|
|
ε-Poly-L-lysine hydrochloride (MV 2000-5000) is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine hydrochloride inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine hydrochloride has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine hydrochloride can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine hydrochloride is also used as a liposome stabilizer .
|
-
- HY-153234
-
|
|
CD19
Liposome
|
Inflammation/Immunology
Cancer
|
|
CD19 car circRNA-LNP is a lipid nanoparticle (LNP) containing CD19 car circRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car circRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .
|
-
- HY-W010572R
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-Thioglycerol (Standard) is the analytical standard of 1-Thioglycerol. This product is intended for research and analytical applications. 1-Thioglycerol, commonly used as a reducing agent in various biochemical and biophysical applications, especially in protein chemistry and molecular biology, it can protect proteins from oxidation and denaturation, and can reduce disulfide bonds to thiols base, which can then be modified or analyzed. In addition, 1-Thioglycerol has been investigated for potential medical applications, including as an inhibitor of cystic fibrosis, which may help improve the function of lung cells, and has also been studied for Used in the preparation of metal nanoparticles and as a stabilizer for certain pharmaceutical preparations.
|
-
- HY-164014
-
|
|
Autophagy
|
Cardiovascular Disease
|
|
9-CCN is a lipid compound that specifically targets macrophages. 9-CCN can be used in the study of cardiovascular and cerebrovascular diseases .
|
-
- HY-116604
-
|
PD 139530
|
PI3K
Akt
|
Cancer
|
|
RLX (PD 139530) is a PI3K/Akt/FoxO3a signaling inhibitor, possessing significant therapeutic potential in experimental colon cancer. RLX can effectively modulate the tumor microenvironment, enhancing the efficacy of cancer immunotherapy. RLX demonstrates the ability to improve the retention time of therapeutic agents within the tumor microenvironment by utilizing advanced nanoparticle delivery systems. RLX can be integrated with various treatment modalities, such as chemotherapy and radiotherapy, to enhance overall tumor therapy effectiveness. RLX highlights the necessity for further research into the tumor microenvironment’s dynamics to develop more tailored treatment approaches for diverse tumor types.
|
-
- HY-159746
-
|
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
|
HS801 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
|
-
- HY-159748
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
M402 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
|
-
- HY-159754
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
HS201 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
|
-
- HY-D0098
-
|
N-(5-Fluoresceinyl)maleimide
|
Fluorescent Dye
|
Others
|
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
|
-
- HY-159753
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
HS105 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
|
-
- HY-159743
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
M101 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
|
-
- HY-159751
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
HS101 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
|
-
- HY-159744
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
M103 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
|
-
- HY-159747
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
M401 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
|
-
- HY-159750
-
|
|
Toll-like Receptor (TLR)
|
Inflammation/Immunology
|
|
M903 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
|
-
- HY-169480
-
|
|
Liposome
|
Infection
Cancer
|
|
Lipid C2 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNP) for mRNA delivery in vivo. LNPs containing Lipid C2 and encapsulating an mRNA reporter selectively accumulate in the liver and spleen but not the heart, lungs, or kidneys in mice. LNP containing Lipid C2 and encapsulating mRNA encoding the Epstein-Barr virus (EBV) protein latent membrane protein 2 (LMP-2), in combination with an anti-programmed cell death protein 1 (PD-1) antibody, decrease tumor volume and reverse T cell exhaustion, as well as increase the percentage of CD3 +CD8 + central and CD3 +CD8 + effector memory T cells and decrease the percentage of CD3 + T cells expressing Pd-1, in the spleen in a CT26 murine EBV-infected colon cancer model .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0917
-
|
|
DNA Stain
|
|
TO-PRO 1 is a DNA binding fluorochrome, that atached to the surface of the Feraheme (FH) nanoparticle (NP), to obtain a fluorochrome-functionalized NP. TO-PRO 1 binds DNA through intercalation, and acts as a vital fluorochrome for necrotic cells .
|
-
- HY-D1540
-
|
Cy 5.5 amine; Lumiprobe Cy 5.5 amine
|
Fluorescent Dyes/Probes
|
|
Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
|
-
- HY-158082A
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 20000
|
Cell Assay Reagents
Fluorescent Dyes/Probes
|
|
TRITC-dextran, MW 20000 (Tetramethyl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
-
- HY-D2514
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-DSPE (MW 1000) is a compound for the labeling and visualization of nanoparticles or other materials. Cy3-PEG-DSPE (MW 1000) has a variety of applications including drug delivery, cellular imaging, tracing of bioprocesses, and the study of interactions at the molecular level.
|
-
- HY-D2518
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-DSPE (MW 10000) is a compound for the labeling and visualization of nanoparticles or other materials. Cy3-PEG-DSPE (MW 10000) has a variety of applications including drug delivery, cellular imaging, tracing of bioprocesses, and the study of interactions at the molecular level.
|
-
- HY-D2314
-
|
|
Dyes
|
|
Cyanine 7-amine (chloride hydrochloride) can be used to label cationic nanoparticles (NPs) or to NP conjugates (NPCs). It can track the residence time and clearance of nanoparticles in the body .
|
-
- HY-D0356
-
|
|
Dyes
|
|
Eriochrome Black A is an azo dye that can be removed from water by an adsorbent made of magnetic NiFe2O4 nanoparticles.
|
-
- HY-D2429
-
|
|
Fluorescent Dyes/Probes
|
|
Dextran-PEG-Cy3 is the Cy3 (HY-D0822)-labeled Dextran-PEG conjugate. Dextran-PEG is used as polymer-polymer systems for the high biocompatibility to maintain cell osmolarity. Dextran-PEG coatings can reduce nanoparticle cytotoxicity .
|
-
- HY-D1600
-
|
|
Dyes
|
|
Sulfo-Cyanine5.5 maleimide potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .
|
-
- HY-D2526
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3 IRGD-PEG-DSPE is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy3 IRGD-PEG-DSPE can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2517
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-DSPE (MW 5000) is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling. Cy3-PEG-DSPE (MW 5000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2544
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5-PEG-DSPE (MW 5000) is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG-DSPE (MW 5000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2542
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5-PEG-DSPE (MW 2000) is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG-DSPE (MW 2000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D0153
-
|
|
Fluorescent Dyes/Probes
|
|
Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL). Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly(lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles .
|
-
- HY-D2541
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5-PEG-DSPE (MW 1000) is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG-DSPE (MW 1000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2516
-
|
|
Fluorescent Dyes/Probes
|
|
Cy3-PEG-DSPE (MW 3400) is a PEG phospholipid with Cy3 (HY-D0822) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy3-PEG-DSPE (MW 3400) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2543
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5-PEG-DSPE (MW 3400) is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG-DSPE (MW 3400) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2545
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5-PEG-DSPE (MW 10000) is a PEG phospholipid with Cy5 (HY-D0821) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5-PEG-DSPE (MW 10000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2567
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-DSPE (MW 5000) is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG-DSPE (MW 5000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2566
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-DSPE (MW 3400) is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG-DSPE (MW 3400) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2565
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-DSPE (MW 2000) is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG-DSPE (MW 2000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2564
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-DSPE (MW 1000) is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG-DSPE (MW 1000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D2568
-
|
|
Fluorescent Dyes/Probes
|
|
Cy5.5-PEG-DSPE (MW 10000) is a PEG phospholipid with Cy5.5 (HY-D0924) dye used in protein/nucelic acid labeling and fluorescence microscopy. Cy5.5-PEG-DSPE (MW 10000) can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
-
- HY-D0948
-
|
|
Dyes
|
|
Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO2 nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .
|
-
- HY-D0098
-
|
N-(5-Fluoresceinyl)maleimide
|
Fluorescent Dyes/Probes
|
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
|
| Cat. No. |
Product Name |
Type |
-
- HY-141629
-
|
Sphingomyelin 16:0
|
Drug Delivery
|
|
N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles .
|
-
- HY-148648
-
|
|
Drug Delivery
|
|
Lipid 29 is an ionizable amino lipid. Lipid 29 can be used to form lipid nanoparticles .
|
-
- HY-W441014
-
|
DSPE-PEG2000-NHS
|
Drug Delivery
|
|
DSPE-PEG-NHS, MW 2000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-W040193
-
DSPC
4 Publications Verification
1,2-Distearoyl-sn-glycero-3-PC; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine
|
Drug Delivery
|
|
DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
|
-
- HY-134541
-
SM-102
Maximum Cited Publications
19 Publications Verification
|
Drug Delivery
|
|
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
|
-
- HY-46759
-
|
|
Drug Delivery
|
|
Genevant CL1 is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery [1][2].
|
-
- HY-153187
-
|
|
Drug Delivery
|
|
LNP Lipid-4 (Compound 8-8) is a lipid compound. LNP Lipid-4 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-4 has potential applications in the transportation of biologically active substances .
|
-
- HY-150241
-
|
|
Drug Delivery
|
|
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .
|
-
- HY-133952
-
|
|
Drug Delivery
|
|
7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents .
|
-
- HY-141674
-
|
|
Drug Delivery
|
|
DMG-PEG is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
|
-
- HY-143700
-
|
|
Drug Delivery
|
|
18:0 DAP can be used to formulate lipid nanoparticles (LNPs), which mRNA is encapsulated in their core .
|
-
- HY-W094581
-
|
|
Drug Delivery
|
|
Gold (III) chloride trihydrate is a reducing agent. Gold (III) chromium trihydrate can be used for chemical synthesis of gold nanoparticles (NP) and spirochromene derivatives .
|
-
- HY-Y0102
-
|
2-Mercaptobenzoic acid
|
Drug Delivery
|
|
Thiosalicylic acid (2-Mercaptobenzoic acid) is a stabilizer that can be used in the synthesis of metal nanoparticles. Thiosalicylic acid is a biomaterial or organic compound that can be used in life science research .
|
-
- HY-145794
-
|
|
Drug Delivery
|
|
ZA3-Ep10 is a zwitterionic lipid used in lipid nanoparticles formulation for in vivo RNA delivery and non-viral CRISPR/Cas gene editing.
|
-
- HY-148033
-
|
N,N,N-Trimethylchitosan
|
Drug Delivery
|
|
Trimethyl chitosan (N,N,N-Trimethylchitosan) is a water-soluble multifunctional polymer which is a Chitosan (HY-B2144A) derivative. Trimethyl chitosan can be used for drug delivery and to synthesize nanoparticles .
|
-
- HY-138170
-
|
|
Drug Delivery
|
|
ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
|
-
- HY-153376
-
|
|
Drug Delivery
|
|
LNP Lipid-6 (Compound Lipid 5) is an ionizable lipid (amino lipid). LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) .
|
-
- HY-153375
-
|
|
Drug Delivery
|
|
LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP) .
|
-
- HY-148363
-
|
|
Drug Delivery
|
|
Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .
|
-
- HY-151507
-
|
|
Drug Delivery
|
|
306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
|
-
- HY-W440835
-
|
DSPE-PEG(2000)-DBCO
|
Drug Delivery
|
|
DSPE-PEG-DBCO, MW 2000 is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG-DBCO, MW 2000 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-155902B
-
|
Maleimide-PEG-Hydroxy (MW 1000)
|
Drug Delivery
|
|
Mal-PEG-OH (MW 1000) was used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-155902A
-
|
Maleimide-PEG-Hydroxy (MW 2000)
|
Drug Delivery
|
|
Mal-PEG-OH (MW 2000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-155902
-
|
Maleimide-PEG-Hydroxy (MW 5000)
|
Drug Delivery
|
|
Mal-PEG-OH (MW 5000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-W441002
-
|
|
Drug Delivery
|
|
DSPE-succinic acid is a phophalipid capped with a carboxylic acid moiety. The carboxylic acid moiety is reactive with amine to from a stable amide linkage. DSPE-succinic acid can be used to prepare nanoparticles or liposomes for agent nanocarrier to deliver therapeutics .
|
-
- HY-W105426
-
|
[3-(Methacryloyloxy)propyl]trimethoxysilane
|
Biochemical Assay Reagents
|
|
3-(Trimethoxysilyl)propyl methacrylate ([3-(Methacryloyloxy)propyl]trimethoxysilane) is a silane coupling agent that can be used to modify TiO2 nanoparticles. 3-(Trimethoxysilyl)propyl methacrylate is a biomaterial or organic compound that can be used for life science research .
|
-
- HY-112752
-
|
|
Drug Delivery
|
|
Gal-C4-Chol is a glycosylated cholesterol derivative. Gal-C4-Chol can be used as a ligand for asialoglycoprotein receptors (ASGPR) to prepare Galactosylated (Gal) liposomes. Gal-C4-Chol can be used to prepare simple lipid-based nanoparticles .
|
-
- HY-125924
-
|
DSPE-PEG-NH2, MW 2000 ammonium; DSPE-PEG(2000) Amine ammonium
|
Drug Delivery
|
|
DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents .
|
-
- HY-136304
-
|
|
Drug Delivery
|
|
NHS-PEG1-SS-PEG1-NHS is a reversible linker for biomacromolecule link with active small molecule. NHS-PEG1-SS-PEG1-NHS can be used in proteins liposomes or nanoparticles .
|
-
- HY-112760
-
|
DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium
|
Drug Delivery
|
|
18:0 mPEG2000 PE sodium can be used for the preparation of stabilized nucleic acid-lipid particllipid particles (SNALPs). SNALPs represent some of the earliest and best functional siRNA-ABC nanoparticles described .
|
-
- HY-112764
-
|
|
Drug Delivery
|
|
DMG-PEG 2000 is used?for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the?lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
|
-
- HY-157252
-
|
|
Drug Delivery
|
|
CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice .
|
-
- HY-139306
-
|
|
Drug Delivery
|
|
BAMEAO16B is a lipid nanoparticle. BAMEAO16B integrated with disulfide bonds, can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA in response to the reductive intracellular environment for genome editing. BAMEAO16B can be used for the research of gene editing .
|
-
- HY-151508
-
|
|
Drug Delivery
|
|
Diamino lipid DAL4 is diamino lipid for the preparation of lipid nanoparticles (LNPs) encapsulated with mRNAs encoding cytokines including IL-12, IL-27 and GM-CSF. Diamino lipid DAL4 delivers mRNA to tumor cells to exert anti-tumor activity .
|
-
- HY-W414069
-
|
|
Drug Delivery
|
|
Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery .
|
-
- HY-172168A
-
|
|
Drug Delivery
|
|
Orange Fluorescent PLGA nanoparticles, 200nm a nanoparticle made from the polymer PLGA and labeled with an orange fluorescent dye. Orange Fluorescent PLGA nanoparticles, 200nm can be used for drug delivery and for tracing .
|
-
- HY-172174
-
|
|
Drug Delivery
|
|
Red Fluorescent PLGA nanoparticles, 100nm is a nanoparticle made from the polymer PLGA and labeled with a red fluorescent dye. Red Fluorescent PLGA nanoparticles, 100nm can be used for drug delivery and for tracing .
|
-
- HY-172168B
-
|
|
Drug Delivery
|
|
Orange Fluorescent PLGA nanoparticles, 500nm a nanoparticle made from the polymer PLGA and labeled with an orange fluorescent dye. Orange Fluorescent PLGA nanoparticles, 500nm can be used for drug delivery and for tracing .
|
-
- HY-172168
-
|
|
Drug Delivery
|
|
Orange Fluorescent PLGA nanoparticles, 100nm a nanoparticle made from the polymer PLGA and labeled with an orange fluorescent dye. Orange Fluorescent PLGA nanoparticles, 100nm can be used for drug delivery and for tracing .
|
-
- HY-172174B
-
|
|
Drug Delivery
|
|
Red Fluorescent PLGA nanoparticles, 500nm is a nanoparticle made from the polymer PLGA and labeled with a red fluorescent dye. Red Fluorescent PLGA nanoparticles, 500nm can be used for drug delivery and for tracing .
|
-
- HY-172174A
-
|
|
Drug Delivery
|
|
Red Fluorescent PLGA nanoparticles, 200nm is a nanoparticle made from the polymer PLGA and labeled with a red fluorescent dye. Red Fluorescent PLGA nanoparticles, 200nm can be used for drug delivery and for tracing .
|
-
- HY-172376
-
|
|
Drug Delivery
|
|
PCL Nanoparticles, 100nm are nanoparticles made of the polymer polycaprolactone (PCL) that can be used for drug delivery .
|
-
- HY-168943
-
|
|
Drug Delivery
|
|
PLGA nanoparticles, 100 nm is a nanoparticle made from the polymer PLGA that can be used for drug delivery .
|
-
- HY-172376A
-
|
|
Drug Delivery
|
|
PCL Nanoparticles, 500nm are nanoparticles made of the polymer polycaprolactone (PCL) that can be used for drug delivery .
|
-
- HY-168943A
-
|
|
3D Bioprinting
|
|
PLGA nanoparticles, 500 nm is a nanoparticle made from the polymer PLGA that can be used for drug delivery .
|
-
- HY-168943B
-
|
|
Drug Delivery
|
|
PLGA nanoparticles, 500 nm is a nanoparticle made from the polymer PLGA that can be used for drug delivery .
|
-
- HY-168943C
-
|
|
Drug Delivery
|
|
PLGA nanoparticles, 1μm is a nanoparticle made from the polymer PLGA that can be used for drug delivery .
|
-
- HY-W011696
-
|
cis-1-Amino-9-octadecene, 80-90%
|
Surfactants
|
|
Oleylamine, 80-90% (cis-1-Amino-9-octadecene, 80-90%) is a long-chain primary alkylamine, which can be used in nanoparticle synthesis as a solvent, surfactant, and reducing agent. Oleylamine, 80-90% forms metastable complexes with metal ions, which can be controllably decomposed to produce nanoparticles. Oleylamine, 80-90% can control the morphology of nanoparticle, prevent the nanoparticle aggregation, and reduce metal precursors to metal nanoparticles .
|
-
- HY-168947A
-
|
|
Drug Delivery
|
|
Green Fluorescent PLGA nanoparticles, 200nm is a PLGA nanoparticle labeled with a green fluorescent dye and is commonly used in imaging and diagnostic applications.
|
-
- HY-168947B
-
|
|
Drug Delivery
|
|
Green Fluorescent PLGA nanoparticles, 500nm is a PLGA nanoparticle labeled with a green fluorescent dye and is commonly used in imaging and diagnostic applications.
|
- HY-168947
-
|
|
Drug Delivery
|
|
Green Fluorescent PLGA nanoparticles, 100nm is a PLGA nanoparticle labeled with a green fluorescent dye and is commonly used in imaging and diagnostic applications.
|
- HY-144012A
-
|
16:0 PEG350 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Drug Delivery
|
|
DPPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144012B
-
|
16:0 PEG550 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Drug Delivery
|
|
DPPE-PEG550 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155926
-
|
14:0 PEG750 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
Drug Delivery
|
|
DMPE-PEG750 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155931
-
|
DOPE-PEG550; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Drug Delivery
|
|
18:1 PEG550 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144013H
-
|
DSPE-mPEG5000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Drug Delivery
|
|
18:0 mPEG5000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144013B
-
|
DSPE-mPEG550 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Drug Delivery
|
|
18:0 mPEG550 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144012C
-
|
16:0 PEG750 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
Drug Delivery
|
|
DPPE-PEG750 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155924
-
|
14:0 PEG350 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Drug Delivery
|
|
DMPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155927
-
|
14:0 PEG1000 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Drug Delivery
|
|
DMPE-PEG1000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144012E
-
|
16:0 PEG3000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Drug Delivery
|
|
DPPE-PEG3000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144013A
-
|
DSPE-mPEG350 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Drug Delivery
|
|
18:0 mPEG350 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144013D
-
|
DSPE-mPEG1000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Drug Delivery
|
|
18:0 mPEG1000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155934
-
|
DOPE-PEG5000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Drug Delivery
|
|
18:1 PEG5000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144012D
-
|
16:0 PEG1000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Drug Delivery
|
|
DPPE-PEG1000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155933
-
|
DOPE-PEG3000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Drug Delivery
|
|
18:1 PEG3000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155932
-
|
DOPE-PEG1000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
Drug Delivery
|
|
18:1 PEG1000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144012H
-
|
16:0 PEG5000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Drug Delivery
|
|
DPPE-PEG5000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155925
-
|
14:0 PEG550 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
Drug Delivery
|
|
DMPE-PEG550 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144013E
-
|
DSPE-mPEG3000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Drug Delivery
|
|
18:0 mPEG3000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155930
-
|
DOPE-PEG350; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
Drug Delivery
|
|
18:1 PEG350 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144013C
-
|
DSPE-mPEG750 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
Drug Delivery
|
|
18:0 mPEG750 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155929
-
|
14:0 PEG5000 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
Drug Delivery
|
|
DMPE-PEG5000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155928
-
|
14:0 PEG3000 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
Drug Delivery
|
|
DMPE-PEG3000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-W440810
-
|
|
Drug Delivery
|
|
Undecyl 6-bromohexanoate can be useful for the preparation of lipid nanoparticles.
|
- HY-147332
-
|
|
Drug Delivery
|
|
TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
|
- HY-150115
-
|
|
Drug Delivery
|
|
Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
- HY-150118
-
|
|
Drug Delivery
|
|
Lipid 8 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
- HY-150117
-
|
|
Drug Delivery
|
|
Lipid 6 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
- HY-153378
-
|
|
Drug Delivery
|
|
Lipid 15 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
- HY-150116
-
|
|
Drug Delivery
|
|
Lipid 1 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
- HY-134782
-
|
|
Drug Delivery
|
|
OF-Deg-Lin is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
- HY-153377
-
|
|
Drug Delivery
|
|
Lipid 14 is a potent ionizable lipid and can be used to synthesize lipid nanoparticles (LNPs) .
|
- HY-153373
-
|
|
Drug Delivery
|
|
4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).
|
- HY-142979
-
|
|
Drug Delivery
|
|
DSPE-PEG 2000 is a PEG-lipid that can be used to form micelles as nanoparticles for drug delivery .
|
- HY-W440813
-
|
|
Drug Delivery
|
|
Heptadecan-9-yl 8-bromooctanoate can be useful for the building or modification of lipid nanoparticles.
|
- HY-141892A
-
|
DSPE PEG(2000) Carboxylic Acid sodium
|
Drug Delivery
|
|
DSPE-PEG Carboxylic acid (sodium), MW 2000 is a PEG-lipid that can be used in the preparation of drug delivery nanoparticles .
|
- HY-168374A
-
|
|
Drug Delivery
|
|
DSPE-PEG1000-mannose is an amphiphilic molecule that can be used to synthesize lipid nanoparticles .
|
- HY-112755
-
|
|
Drug Delivery
|
|
DODMA is a cationic lipid that can be used to prepare lipid nanoparticles. DODMA can be used for drug delivery .
|
- HY-158082C
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 70000
|
Cell Assay Reagents
|
|
TRITC-dextran, MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye, with the molecular weight of 70 kD. TRITC-dextran, MW 70000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 70000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
- HY-158082
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 4000
|
Cell Assay Reagents
|
|
TRITC-dextran MW 4000 (Tetramethyl rhodamine isothiocyanate glucan, MW 4000) is a fluorescent dye, with the molecular weight of 4 kD. TRITC-dextran MW 4000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 4000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 4000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
- HY-158082E
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 500000
|
Cell Assay Reagents
|
|
TRITC-dextran, MW 500000 (Tetramethyl rhodamine isothiocyanate glucan, MW 500000) is a fluorescent dye, with the molecular weight of 500 kD. TRITC-dextran, MW 500000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 500000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 500000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
- HY-158082A
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 20000
|
Cell Assay Reagents
Fluorescent Dyes/Probes
|
|
TRITC-dextran, MW 20000 (Tetramethyl rhodamine isothiocyanate glucan, MW 20000) is a fluorescent dye, with the molecular weight of 20 kD. TRITC-dextran MW 20000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 20000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 20000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
- HY-158082B
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 40000
|
Cell Assay Reagents
|
|
TRITC-dextran, MW 40000 (Tetramethyl rhodamine isothiocyanate glucan, MW 40000) is a fluorescent dye, with the molecular weight of 40 kD. TRITC-dextran MW 40000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 40000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 40000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
- HY-158082D
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 150000
|
Cell Assay Reagents
|
|
TRITC-dextran, MW 150000 (Tetramethyl rhodamine isothiocyanate glucan, MW 150000) is a fluorescent dye, with the molecular weight of 150 kD. TRITC-dextran, MW 150000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 150000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 150000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
- HY-W036410
-
|
3-Aminopropyltrimethoxysilane
|
Biochemical Assay Reagents
|
|
Aminopropyltrimethoxysilane (3-Aminopropyltrimethoxysilane) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
- HY-158082H
-
|
Tetramethyl rhodamine isothiocyanate glucan, MW 2000000
|
Cell Assay Reagents
|
|
TRITC-dextran, MW 2000000 (Tetramethyl rhodamine isothiocyanate glucan, MW 2000000) is a fluorescent dye, with the molecular weight of 2000 kD. TRITC-dextran, MW 2000000 exhibits an excitation wavelength of 555 nm. TRITC-dextran, MW 2000000 is follicular and vessel penetrate, which is dependent on the molecular weight. TRITC-dextran, MW 2000000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
|
- HY-170455
-
|
|
Drug Delivery
|
|
18:1 PE (DOPE) pSar25 is a derivative of polyethylene glycol that can be used for liposomal and lipid nanoparticle delivery systems.
|
- HY-153372
-
|
|
Drug Delivery
|
|
93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).
|
- HY-153186
-
|
|
Drug Delivery
|
|
LNP Lipid-3 is an ionizable lipid extracted from patent WO2021113777A, and can be used for the generation of Lipid nanoparticles (LNPs).
|
- HY-W344875
-
|
|
Drug Delivery
|
|
Sodium ligninsulfonate is a natural polymer compound with good surface activity, which can be used as a stabilizer for liposomes, a promoter for nanocrystal production, and a dispersant for nanoparticle preparation.
|
- HY-W590532
-
|
|
Drug Delivery
|
|
306-O12B is an ionizable cationic lipid used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA .
|
- HY-153235
-
|
|
Drug Delivery
|
|
COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing mRNA encoding COVID-19 Spike Protein , suitable for detection of RNA delivery, translation efficiency, cell viability, etc. COVID-19 Spike Protein is the novel coronavirus pneumonia spike protein located on the membrane surface. COVID-19 Spike Protein undertakes the functions of virus binding to host cell membrane receptors and membrane fusion, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design .
|
- HY-B1620L
-
|
PVP, average Mw~40000; Polyvidone, average Mw~40000; Povidone, average Mw~40000
|
Thickeners
|
|
Polyvinylpyrrolidone, average Mw~40000 is a multifunctional synthetic polymer with an average molecular weight of 40,000. Polyvinylpyrrolidone is widely used to synthesize nanoparticles .
|
- HY-W250183B
-
|
Polyethylene glycol octadecyl ether (n～20)
|
Surfactants
|
|
Polyoxyethylene (20) stearyl ether (Polyethylene glycol octadecyl ether) is a polyethylene glycolated lipid surfactant that can be used in the formation and stabilization studies of nanoparticles .
|
- HY-B1620M
-
|
PVP, average Mw～55000; Polyvidone, average Mw～55000; Povidone, average Mw～55000
|
Thickeners
|
|
Polyvinylpyrrolidone, average Mw～55000 is a multifunctional synthetic polymer with an average molecular weight of 55,000. Polyvinylpyrrolidone is widely used to synthesize nanoparticles .
|
- HY-B1620J
-
|
PVP, average Mw～10000; Polyvidone, average Mw～10000; Povidone, average Mw～10000
|
Thickeners
|
|
Polyvinylpyrrolidone, average Mw～10000 is a multifunctional synthetic polymer with an average molecular weight of 10,000. Polyvinylpyrrolidone is widely used to synthesize nanoparticles .
|
- HY-B1620N
-
|
PVP, average Mw～360000; Polyvidone, average Mw～360000; Povidone, average Mw～360000
|
Thickeners
|
|
Polyvinylpyrrolidone, average Mw～360000 is a multifunctional synthetic polymer with an average molecular weight of 360,000. Polyvinylpyrrolidone is widely used to synthesize nanoparticles .
|
- HY-172357
-
|
|
Drug Delivery
|
|
Poly (3-hydroxybutyric acid-co-3-hydroxyvaleric acid) is a biodegradable polymer that can be used to construct nanoparticles for drug delivery .
|
- HY-W440811
-
|
|
Drug Delivery
|
|
6-Bromohexyl 2-hexyldecanoate is a lipid. 6-Bromohexyl 2-hexyldecanoate can be used to build lipid nanoparticles and nanomaterials .
|
- HY-149167
-
|
ATX 100
|
Drug Delivery
|
|
ATX-0126 (Compound 2) is a Thiocarbamate-Based Ionizable Lipid. ATX-0126 can be used as an excipient in mRNA-encapsulating lipid nanoparticle .
|
- HY-B1620O
-
|
PVP, average Mw~1300000; Polyvidone, average Mw~1300000; Povidone, average Mw~1300000
|
Co-solvents
|
|
Polyvinylpyrrolidone, average Mw~1300000 is a multifunctional synthetic polymer with an average molecular weight of 1,300,000. Polyvinylpyrrolidone is widely used to synthesize nanoparticles .
|
- HY-112756
-
|
|
Drug Delivery
|
|
PEG2000-DGG is a synthetic lipid. PEG2000-DGG can be used in lipid-based nanoparticle (LNP) delivery systems .
|
- HY-153852
-
|
|
Drug Delivery
|
|
1LNP Lipid-7 (Compound 7013) is a lipid. LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) and for drug delivery .
|
- HY-46759A
-
|
|
Drug Delivery
|
|
Genevant CL1 monohydrochloride is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery .
|
- HY-W441012
-
|
|
Drug Delivery
|
|
DSPE-PEG-NHS, MW 600 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
- HY-149156
-
|
|
Drug Delivery
|
|
Lipid C24 is a cationic ionizable lipid, and can be used in the formation of lipid nanoparticles (LNPs). Lipid C24 can be used for research of delivery of nucleic acids .
|
- HY-W441015A
-
|
|
Drug Delivery
|
|
DSPE-m-PEG-NHS (MW 3400) is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
- HY-156630
-
|
|
Drug Delivery
|
|
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
|
- HY-148830
-
|
|
Drug Delivery
|
|
Piperazine-bis(ethyl octadeca-9,12-dienoate) is a cationic lipid extracted from patent WO2023036148A1, and can be used for the generation of Lipid nanoparticles (LNPs).
|
- HY-156630A
-
|
|
Drug Delivery
|
|
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
|
- HY-W441021
-
|
|
Drug Delivery
|
|
DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon, and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment.
|
- HY-153371
-
|
|
Drug Delivery
|
|
50-C2-C9-4tail has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo.
|
- HY-W127410
-
|
|
Biochemical Assay Reagents
|
|
Hexanoic anhydride is used as a reactant for the synthesis of acremomannolipin A. For the green synthesis of acyclovir dipivoxil (acyclovir proagent), for the preparation of hexanoyl-modified chitosan nanoparticles, chitosan-based polymer surfactants by N-acylation of chitosan .
|
- HY-W008034
-
|
|
Drug Delivery
|
|
Fmoc-L-Trp(Boc)-OH is an amino acid derivative with a protective group, which has the ability to self-assemble and form nanoparticles. Fmoc-L-Trp(Boc)-OH can be used in the study of anticancer drug delivery .
|
- HY-W440722
-
|
|
Drug Delivery
|
|
Cholesterol-PEG-Thiol (MW 1000) is a PEGylated lipid that forms micelles in water and can be used to prepare liposomes or nanoparticles as drug delivery systems. The thiol moiety reacts with maleimide to form a stable thioether bond .
|
- HY-D1005A23
-
|
PEG-PPG-PEG, 4400 (Averag)
|
Co-solvents
|
|
Poloxamer 401 L121 is block polymer of polyoxyethylene and polyoxypropylene. Poloxamer 401 L121 is utilized as lymphotrophic particles in nanoparticle engineering, as inhibitor of multidrug resistance and adjuvant activities or as surfactants and emulsifying agents in cosmetics .
|
- HY-112773
-
|
|
Drug Delivery
|
|
1,1′,1′′,1′′′-[1,4-Piperazinediylbis(2,1-ethanediylnitrilo)]tetrakis[2-dodecanol] is a lipid/lipidoid used in preparation of lipid-based or lipidoid nanoparticles .
|
- HY-148049
-
|
|
Drug Delivery
|
|
TT3 is an ionizable lipid-like materials for mRNA and CRISPR/Cas9 delivery .
|
- HY-153737
-
|
|
Drug Delivery
|
|
113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
|
- HY-148855
-
|
|
Drug Delivery
|
|
OF-C4-Deg-Lin is an ionizable lipid with varied linker lengths. OF-C4-Deg-Lin can be used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA .
|
- HY-107799
-
|
|
Co-solvents
|
|
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .
|
- HY-134781
-
CKK-E12
1 Publications Verification
|
Drug Delivery
|
|
CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,
|
- HY-W590547
-
|
|
Drug Delivery
|
|
(6-(4-Hydroxybutylamino)hexyl)carbamic undecyl is a lipid with a terminal hydroxyl group, which is used to construct or modify lipid nanoparticles (LNP). (6-(4-Hydroxybutylamino)hexyl)carbamic undecyl can be used in drug delivery research .
|
- HY-W440917
-
|
|
Drug Delivery
|
|
DSPE-PEG-FITC, MW 5000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
- HY-W440915
-
|
|
Drug Delivery
|
|
DSPE-PEG-FITC, MW 2000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
- HY-W013122
-
|
Cholesteryl butyrate
|
Biochemical Assay Reagents
|
|
Cholesteryl n-butyrate is a cholesterol ester composed of cholesterol and butyrate, two naturally occurring substances. Cholesteryl n-butyrate can be used to synthesize solid lipid nanoparticles (SLNs) with inhibitory activity on the adhesion and migration of colon cancer cells, providing a delivery system for the anticancer drug butyrate .
|
- HY-W440916
-
|
|
Drug Delivery
|
|
DSPE-PEG-FITC, MW 3400 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
|
- HY-Y0623
-
|
HOSu; 1-Hydroxy-2,5-pyrrolidinedione
|
Biochemical Assay Reagents
|
|
N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is an activated ester commonly used in bioconjugation technologies such as protein labeling with fluorescent dyes and enzymes, chromatography supports, beads, nanoparticles, and microarrays Surface activation of glass slides, and chemically synthesized peptides .
|
- HY-W073196
-
|
Tetrachloroauric(Ⅲ) acid hydrate (48% Au basis)
|
Biochemical Assay Reagents
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Gold(Ⅲ) chloride hydrate (48% Au basis) (Tetrachloroauric(Ⅲ) acid hydrate (48% Au basis)) can be used to prepare gold nanoparticles. Gold(Ⅲ) chloride hydrate (48% Au basis) is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-W440921
-
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Drug Delivery
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DSPE-PEG-Rhodamine, MW 5000 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
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- HY-142981
-
|
DODA
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Drug Delivery
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|
Dioctadecylamine (DODA) is a secondary amine that has been shown to self-organize in plate-like structures in aqueous solution. Dioctadecylamine exhibits sufficiently hydrophobic properties of nanoparticles and good dispersibility in nonpolar solvent. Dioctadecylamine does not form a monolayer above pH 3.9 .
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- HY-W440906
-
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Drug Delivery
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|
DSPE-PEG-Vinylsulfone, MW 3400 is a thiol reactive PEG lipid. The polymer can self-assemble spontaneously in aqueous solution to form lipid bilayer and be used to prepare nanoparticles/liposomes for drug delivery, for example mRNA vaccine or DNA vaccine. Reagent grade, for research use only.
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- HY-W440920
-
|
|
Drug Delivery
|
|
DSPE-PEG-Rhodamine, MW 3400 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
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- HY-W440891
-
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Drug Delivery
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|
DSPE-PEG-OH, MW 1000 is a hydroxyl terminated phospholipid PEG polymer. The hydrophobic tails allow for the encapsulation and congregation of other hydrophobic drugs. The polymer can be used to prepare liposomes or lipid nanoparticles. Hydroxyl terminal can further derivatize the compound. Reagent grade, for research use only.
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- HY-148702
-
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Drug Delivery
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|
di-Pal-MTO is a palm oil-based lipid produced by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity .
|
- HY-W073196A
-
|
Tetrachloroauric(Ⅲ) acid hydrate (50% Au basis)
|
Biochemical Assay Reagents
|
|
Gold(Ⅲ) chloride hydrate (50% Au basis) (Tetrachloroauric(Ⅲ) acid hydrate (50% Au basis)) is an organic intermediate that can be used to prepare gold nanoparticles. Gold(Ⅲ) chloride hydrate (50% Au basis) is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-W073196B
-
|
Tetrachloroauric(Ⅲ) acid hydrate (52% Au basis)
|
Biochemical Assay Reagents
|
|
Gold(Ⅲ) chloride hydrate (52% Au basis) (Tetrachloroauric(Ⅲ) acid hydrate (52% Au basis)) is an organic intermediate that can be used to prepare gold nanoparticles. Gold(Ⅲ) chloride hydrate (52% Au basis) is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-153136
-
|
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Drug Delivery
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|
LNP Lipid-1 (Method B) is a lipid compound. LNP Lipid-1 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-1 has potential applications in the transport of biologically active substances such as small molecule agents, proteins, and nucleic acids .
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- HY-W440910
-
|
|
Drug Delivery
|
|
DSPE-PEG-Cy3, MW 5000 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-W440909
-
|
|
Drug Delivery
|
|
DSPE-PEG-Cy3, MW 3400 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
- HY-148701
-
|
|
Drug Delivery
|
|
mono-Pal-MTO is a palm oil-based lipid produced by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they show effective siRNA cell delivery and enhance anticancer activity .
|
- HY-W440834
-
|
|
Drug Delivery
|
|
DSPE-PEG-Azide, MW 5000 is a click chemistry reactive phospholipid polyPEG which forms lipid bilayer or micelles in an aqueous solution. The polymer can be used to prepare liposomes or nanoparticles used for delivering nutrients or therapeutic agents, for example mRNA or DNA vaccine. Reagent grade, for research use only.
|
- HY-151506
-
|
|
Drug Delivery
|
|
Phospholipid PL1 is a phospholipid-derived nanoparticle, can deliver costimulatory receptor mRNA (CD137 or OX40) to T cells. Phospholipid PL1 could induce the activation of various immune cells, including T cells and dendritic cells (DCs) in order to boost antitumor immunity .
|
- HY-W440913
-
|
|
Drug Delivery
|
|
DSPE-PEG-Cy5, MW 5000 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
- HY-W440912
-
|
|
Drug Delivery
|
|
DSPE-PEG-Cy5, MW 3400 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
|
- HY-W440681
-
|
|
Drug Delivery
|
|
C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).
|
- HY-W440684
-
|
|
Drug Delivery
|
|
C13-113-tetra tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tetra tail can be formulated into a lipid nanoparticle (LNP).
|
- HY-W440683
-
|
|
Drug Delivery
|
|
C13-112-tetra-tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tetra-tail can be formulated into a lipid nanoparticle (LNP).
|
- HY-152229
-
|
|
Drug Delivery
|
|
G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery .
|
- HY-W440682
-
|
|
Drug Delivery
|
|
C13-113-tri tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tri tail can be formulated into a lipid nanoparticle (LNP).
|
- HY-W440949
-
|
|
Drug Delivery
|
|
Azide-PEG-Silane, MW 2000 is a click reagent which can react with a terminal alkyne via CuAAC or with a cyclooctyne (DBCO/BCN) via SPAAC to form a triazole bond. Silane is a surface modification moiety which can react with hydroxyl group of surface, such as glass, nanoparticles, etc. Reagent grade, for research use only.
|
- HY-W440936
-
|
|
Drug Delivery
|
|
Stearic acid-PEG-Rhodamine, MW 5000 is a fatty acid containing PEG polymer which can self assemble in an aqueous solution to form micelles. The polymer can be used to prepare nanoparticles for drug encapsulation. The red dye rhodamine can be easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
|
- HY-W440935
-
|
|
Drug Delivery
|
|
Stearic acid-PEG-Rhodamine, MW 3400 is a fatty acid containing PEG polymer which can self assemble in an aqueous solution to form micelles. The polymer can be used to prepare nanoparticles for drug encapsulation. The red dye rhodamine can be easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
|
- HY-W073183
-
|
|
Chelators
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|
Dibenzo-24-crown-8-ether is a phase transfer catalyst that can reduce H 2PtCl 6·6H 2O and FeCl 2·4H 2O in a thermal system to synthesize 17 nm monodispersed iron-platinum (FePt) alloy nanoparticles .
|
- HY-W011060
-
|
4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane
|
Biochemical Assay Reagents
|
|
Cryptand 2.2.2 is a metal ion chelator that can be used as a reducing agent and stabilizer to prepare nanoparticles. At room temperature, Cryptand 2.2.2 can serve as a host molecule, using the chelation effect to selectively bind desired ions (such as Zn 2+, Co 2+, Ni 2+, Cu 2+) .
|
- HY-W441002R
-
|
|
Drug Delivery
|
|
Taurine (Standard) is the analytical standard of Taurine. This product is intended for research and analytical applications. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes .
|
- HY-145411
-
|
|
Drug Delivery
|
|
PEG2000-C-DMG, a pegylated lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3′ untranslated region of transthyretin mRNA .
|
- HY-W440953
-
|
|
Drug Delivery
|
|
Stearic acid-PEG-CH2CO2H, MW 1000 is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The terminal carboxyl can react with amine via condensation reaction in the presence of HATU/EDC activator. Reagent grade, for research use only.
|
- HY-W440938
-
|
|
Drug Delivery
|
|
Stearic acid-PEG-FITC, MW 2000 is an amphiphatic polyPEG which can self assemble to form micelles in water. The polymer can be used to encapsulate therapeutic agent. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
- HY-148842
-
|
|
Drug Delivery
|
|
C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity .
|
- HY-W440939
-
|
|
Drug Delivery
|
|
Stearic acid-PEG-FITC, MW 3400 is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
- HY-W440940
-
|
|
Drug Delivery
|
|
Stearic acid-PEG-FITC, MW 5000 is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
- HY-W440884
-
|
|
Drug Delivery
|
|
DSPE-PEG-Ald, MW 3400 is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
- HY-132141
-
|
5-Propargylamino-dUTP
|
Gene Sequencing and Synthesis
|
|
5-PA-dUTP (5-Propargylamino-dUTP) is a C5-modified nucleotide and can be incorporated into DNA nanoparticles (DNPs) for photosensitizer delivery . 5-PA-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
- HY-W440833
-
|
|
Drug Delivery
|
|
DSPE-PEG-Azide, MW 3400 is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond. Reagent grade, for research use only.
|
- HY-147112
-
|
|
Enzyme Substrates
|
|
MNP-GAL is MNPs coated with galactose. MNP-Gal can be used as substrate for the assay of NAG and beta-d-galactosidase .
|
- HY-145405
-
|
|
Drug Delivery
|
|
C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
|
- HY-Y1365
-
|
|
Thickeners
|
|
Gelatins is a non-toxic, non carcinogenic, biodegradable, and non irritating natural polymer derived from partial hydrolysis of collagen. Due to its strong liquid absorption and swelling ability, Gelatins has excellent hemostatic properties and can be used as a matrix material for the reduction, growth, and stability of metal nanoparticles. Gelatins can also be used for tumor cell culture and tumor therapy [1][2][3].
|
- HY-153231
-
|
|
Drug Delivery
|
|
eGFP mRNA-LNP is a lipid nanoparticle (LNP) containing eGFP mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .
|
- HY-153232
-
|
|
Drug Delivery
|
|
eGFP circRNA-LNP is a lipid nanoparticle (LNP) containing eGFP circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .
|
- HY-137500
-
|
|
Drug Delivery
|
|
NT1-014B is a potent NT1-lipidoid encapsulated AmB (amphotericin B). NT1-014B dopes the NT-lipidoids into BBB-impermeable lipid nanoparticles (LNPs) gave the LNPs the ability to cross the BBB. NT1-014B enhances brain delivery through intravenous injection .
|
- HY-W440903
-
|
|
Drug Delivery
|
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
- HY-112758
-
|
|
Drug Delivery
|
|
DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies .
|
- HY-113217
-
|
|
Drug Delivery
|
|
Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .
|
- HY-167819
-
|
|
Drug Delivery
|
|
D-Erythro-sphingosyl phosphoinositol is a lipid nanoparticle covalently linked to an antibody with potential activity in targeted compound delivery. D-Erythro-sphingosyl phosphoinositol can enhance the accumulation of compounds in specific cell types. D-Erythro-sphingosyl phosphoinositol may be used as a ligand to enhance the effect of antibodies in immunosuppression. D-Erythro-sphingosyl phosphoinositol can also be used to study the mechanisms related to cell signaling and lipid metabolism.
|
- HY-W440926
-
|
|
Drug Delivery
|
|
DSPE-PEG-DBCO, MW 2000 is a cyclooctyne containing phospholipid PEG polymer. The polymer can self-assemble spontaneously in water to form micelles/lipid bilayer. It can be used to prepare nanoparticles or liposomes as drug carrier in targeted drug delivery system. The DBCO can react with azide molecule via copper free click chemistry to form a stable triazole bond. Reagent grade, for research use only.
|
- HY-153231A
-
|
|
Drug Delivery
|
|
eGFP mRNA-LNP (500ng/uL) is a lipid nanoparticle (LNP) containing eGFP mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .
|
- HY-112624C
-
|
|
Thickeners
|
|
Dextran (MW 40000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds. Dextran has excellent solubility in water, making it useful as a viscosity modifier or stabilizer in foods, paints and adhesives. In the biomedical field, dextran is often used as a plasma expander because of its ability to increase blood volume when administered intravenously. It can also be modified to create dextran-based drug delivery systems, such as targeted nanoparticles.
|
- HY-112624B
-
|
Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)
|
Drug Delivery
Thickeners
|
|
Dextran T70 (MW 70,000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds. Dextran has excellent solubility in water, making it useful as a viscosity modifier or stabilizer in foods, paints and adhesives. In the biomedical field, dextran is often used as a plasma expander because of its ability to increase blood volume when administered intravenously. It can also be modified to create dextran-based drug delivery systems, such as targeted nanoparticles.
|
- HY-W440832
-
|
DSPE-PEG(2000) Azide
|
Drug Delivery
|
|
DSPE-PEG-Azide (MW 2000) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery . DSPE-PEG-Azide (MW 2000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
- HY-W440885
-
|
|
Drug Delivery
|
|
DSPE-PEG-Ald, MW 5000 is a phospholipid PEG polymer which can self-assemble spontaneously in water with their hydrophilic heads oriented toward the water (micelles). The polymer can be used to prepare liposome as a drug nanocarrier for administration of nutrients and therapeutic drugs, such as lipid nanoparticles in mRNA or DNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
- HY-145799
-
|
|
Drug Delivery
|
|
5A2-SC8 is an ionizable amino lipid in lipid nanoparticles (LNPs) that shows high delivery potential and low in vivo toxicity, enabling efficient delivery of small RNAs such as siRNA and miRNA into tumor cells. 5A2-SC8 LNPs can confer a unique delivery fate of RNA within the liver, thereby changing the therapeutic outcomes in cancer models .
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- HY-153229
-
|
|
Drug Delivery
|
|
Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing Firefly luciferase mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. Luciferase is commonly used as a bioluminescent reporter gene for gene regulation and function studies. Firefly Luciferase mRNA will express firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Common luciferase are firefly luciferase and sea kidney luciferase .
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- HY-153230
-
|
|
Drug Delivery
|
|
Firefly luciferase circRNA-LNP is a lipid nanoparticle (LNP) containing Firefly luciferase circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. Luciferase is commonly used as a bioluminescent reporter gene for gene regulation and function studies. Firefly Luciferase circRNA will express firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Common luciferase are firefly luciferase and sea kidney luciferase .
|
- HY-W011060R
-
|
|
Biochemical Assay Reagents
|
|
Cryptand 2.2.2 (Standard) is the analytical standard of Cryptand 2.2.2. This product is intended for research and analytical applications. Cryptand 2.2.2 is a metal ion chelator that can be used as a reducing agent and stabilizer to prepare nanoparticles. At room temperature, Cryptand 2.2.2 can serve as a host molecule, using the chelation effect to selectively bind desired ions (such as Zn2+, Co2+, Ni2+, Cu2+) .
|
- HY-137499
-
|
|
Drug Delivery
|
|
NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
|
- HY-131119
-
|
Dioctadecyldimethylammonium bromide; DODAB
|
Drug Delivery
|
|
Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.
|
- HY-W010572
-
|
alpha-Thioglycerol
|
Biochemical Assay Reagents
|
|
1-Thioglycerol, commonly used as a reducing agent in various biochemical and biophysical applications, especially in protein chemistry and molecular biology, it can protect proteins from oxidation and denaturation, and can reduce disulfide bonds to thiols base, which can then be modified or analyzed. In addition, 1-Thioglycerol has been investigated for potential medical applications, including as an inhibitor of cystic fibrosis, which may help improve the function of lung cells, and has also been studied for Used in the preparation of metal nanoparticles and as a stabilizer for certain pharmaceutical preparations.
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- HY-W250187
-
|
|
Biochemical Assay Reagents
|
|
DDMAB, or didodecyldimethylammonium bromide, is a cationic surfactant commonly used in a variety of industrial and research applications. It belongs to the family of quaternary ammonium compounds and has a positively charged head and a hydrophobic tail, which allows it to be used as a detergent, emulsifier and antimicrobial. Known for its ability to disrupt cell membranes, DDMAB is commonly used in microbiology to selectively isolate and identify bacteria. It is also used in nanotechnology to synthesize metal nanoparticles and other materials. In addition, DDMAB has the ability to interact with and penetrate cell membranes, which has potential applications in drug delivery, gene therapy, and other medical fields.
|
- HY-W250308
-
|
Epsilon-polylysine (MW 3800-4200); ε-Polylysine (MW 3800-4200); ε-PL (MW 3800-4200)
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Cell Assay Reagents
|
|
Epsilon-polylysine is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine is also used as a liposome stabilizer .
|
- HY-153233
-
|
|
Drug Delivery
|
|
CD19 car mRNA (Mouse)-LNP is a lipid nanoparticle (LNP) containing CD19 car mRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car mRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .
|
- HY-W250308A
-
|
Epsilon-polylysine (hydrochloride) (MV 2000-5000); ε-Polylysine (hydrochloride) (MV 2000-5000); ε-PL (hydrochloride) (MV 2000-5000)
|
Cell Assay Reagents
|
|
ε-Poly-L-lysine hydrochloride (MV 2000-5000) is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine hydrochloride inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine hydrochloride has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine hydrochloride can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine hydrochloride is also used as a liposome stabilizer .
|
- HY-153234
-
|
|
Drug Delivery
|
|
CD19 car circRNA-LNP is a lipid nanoparticle (LNP) containing CD19 car circRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car circRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .
|
- HY-W010572R
-
|
|
Biochemical Assay Reagents
|
|
1-Thioglycerol (Standard) is the analytical standard of 1-Thioglycerol. This product is intended for research and analytical applications. 1-Thioglycerol, commonly used as a reducing agent in various biochemical and biophysical applications, especially in protein chemistry and molecular biology, it can protect proteins from oxidation and denaturation, and can reduce disulfide bonds to thiols base, which can then be modified or analyzed. In addition, 1-Thioglycerol has been investigated for potential medical applications, including as an inhibitor of cystic fibrosis, which may help improve the function of lung cells, and has also been studied for Used in the preparation of metal nanoparticles and as a stabilizer for certain pharmaceutical preparations.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P5533
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
CRT, an iron peptide mimic, can bind to apo-transferrin (apo-Tf). CRT can be used to modify nanoparticles, and enhances drug delivery efficiency .
|
-
- HY-P10646
-
|
|
Biochemical Assay Reagents
|
Neurological Disease
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Muscle homing peptide M12 can preferentially bind to surface protein of muscle cells. Muscle homing peptide M12 mediates enhanced cellular uptake of nanoparticles (NPs) in myoblasts in vitro. Muscle homing peptide M12 is covalently conjugated to PLGA-PEG NPs via the N-terminal α-amino groups of peptides using the N-hydroxysuccinimide ester reaction .
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- HY-126721
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- HY-P10510
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Biochemical Assay Reagents
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Others
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R5 peptide is one of the repeating peptide sequences that form the protein diatom in Cylindrotheca fusiformis. R5 peptide can be used as a template for the synthesis of Pd (palladium) nanoparticles (NPs). R5 peptide forms complexes with metal ions through the amine groups in its sequence, and the self-assembled structure of the peptide provides a confined spatial environment for the reduction of metal ions and the nucleation of nanoparticles. R5 peptide can be used in the research of biomimetic nanomaterials .
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- HY-P10679
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MMP
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Cancer
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GPLGLAGGWGERDGS is a peptide with MMP enzyme responsiveness and tumor targeting function, which can be used to monitor enzyme-guided nanoparticle assembly in tumors .
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- HY-P1781A
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Secretin Receptor
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Cancer
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Peptide C105Y TFA, a synthetic and cell-penetrating peptide based on the amino acid sequence corresponding to residues 359-374 of α1-antitrypsin, enhances gene expression from DNA nanoparticles .
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- HY-P10674
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Biochemical Assay Reagents
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Neurological Disease
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QMT-CBT is a near-infrared aggregation-induced luminescent photon. After activation of caspase1 (Cas1), QMT-CBT undergoes a CBT-Cys click reaction to form a cyclic dimer QMT-Dimer (the first aggregate) and assembles into nanoparticles (the second aggregate), turning the AIE signal "on" to enhance imaging of Alzheimer's disease (AD) .
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- HY-P4115
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FABP
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Cancer
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CooP is a linear glioblastoma-targeting nonapeptide. CooP binds to the mammary-derived growth inhibitor/fatty acid binding protein 3 (FABP3) in the glioblastoma cells and its associated vasculature. CooP is used for the targeted delivery of chemotherapy and different nanoparticles .
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- HY-113736
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Amino Acid Derivatives
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Others
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Glycyllysine is a polypeptide that can be used in the synthesis of antibodies and amino acid type gemini surfactants. Glycyllysine has potential applications in modifying plasmid/gemini/lipid (P/G/L) nanoparticles transport carriers .
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- HY-P1781
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Peptides
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Cancer
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Peptide C105Y, a synthetic and cell-penetrating peptide based on the amino acid sequence corresponding to residues 359-374 of α1-antitrypsin, enhances gene expression from DNA nanoparticles .
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- HY-P10052
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VEGFR
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Cancer
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CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is modified with a nearinfrared cyanine dye bearing an alkyne function, allowing both “click” coupling on azido-modified nanoparticles and fluorescence labelling .
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- HY-P10796
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MAPKAPK2 (MK2)
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Inflammation/Immunology
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YARA peptide, a cell-penetrating peptide, is a MK2 inhibitor. YARA-loaded nanoparticles decreases the levels of inflammatory cytokines (IL-1β, IL-6, and TNF-α) in an ex vivo skin culture model. YARA peptide is promising for research of atopic dermatitis (AD) .
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- HY-P1116A
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Bacterial
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Infection
Inflammation/Immunology
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PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1 . PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects .
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- HY-P2299
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HPV
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Cancer
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Protein E7(43-62) is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein) .
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- HY-P2299A
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HPV
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Cancer
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Protein E7(43-62) TFA is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein) .
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- HY-P10680
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Liposome
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Others
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TFE-IDAtp1-LinA is a highly potent amphiphilic carrier, containing a trifluoroethyl-iminodiacetic acid analog of Stp. TFE-IDAtp1-LinA, formed nanoparticles with Cas9 RNP/ssDNA, achieved enhanced green fluorescent protein knockouts with an ED50 of 0.38 nM Cas9/sgRNA ribonucleoproteins (RNP) .
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- HY-P10453
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Peptides
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Others
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Myr5A peptide is an acylated peptide composed of apolipoprotein A1 (ApoA1) analog peptide 5A peptide coupled to the saturated fatty acid myristate. Myr5A peptide self-assembled into lipid nanostructures can be used to encapsulate anthracycline Doxorubicin (HY-15142A) and Valrubicin (HY-13772) for compound release studies in vitro .
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- HY-P10793
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EGFR
Apoptosis
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Cancer
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Cyclic(YCDGFYACYMDV) is a HER2 signaling pathway inhibitor with anti-cancer activity. This compound self-assembles into nanoparticles in aqueous solution and transforms into nanofibers upon specific binding to HER2 on cancer cells. This transformation disrupts HER2 dimerization and subsequent downstream signaling events, leading to cancer cell apoptosis (Apoptosis). The inhibitory effects on HER2 positive breast cancer have been demonstrated to be effective in a murine xenograft model .
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P99974
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nanoparticle albumin-bound Paclitaxel; nanoparticle albumin-bound ABI-007
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Microtubule/Tubulin
Apoptosis
Autophagy
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Cancer
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Nab-Paclitaxel is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015). Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel (Paclitaxel: human albumin=1:9), in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug. Nab-Paclitaxel was associated with higher response rates and better tolerability, with favorable pharmacokinetic properties . (The product size below only indicate the effective content of Paclitaxel. The actual albumin quality depends on the batch. The ratio of each component in this product is Paclitaxel: albumin = 1:7-1:11.)
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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Optimized version of product available:
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-113217S
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Cholesteryl oleate-d7 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .
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- HY-W040193S
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1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70 is the deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].
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-
- HY-N2362S2
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DL-Alanine-d3 is the deuterium labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].
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-
- HY-N2362S
-
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DL-Alanine- 13C-1 is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].
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-
-
- HY-N2362S1
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|
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DL-Alanine- 13C-3 is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].
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-
- HY-141629S1
-
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N-Palmitoyl-D-sphingomyelin-13C is a deuterated labeled N-Palmitoyl-D-sphingomyelin . N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles .
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-
-
- HY-141629S2
-
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N-Palmitoyl-D-sphingomyelin-d9 (Sphingomyelin 16:0-d9) is deuterium labeled N-Palmitoyl-D-sphingomyelin. N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles .
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-
- HY-159176
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Antitumor agent-183 (compound 3f) has antitumor activity with metabolic stability. Antitumor agent-183 inhibits cancer cell growth, with IC50s less than 5 nM for A549, HCT116, and HS578T cells. The albumin-bound nanoparticle formulation of Antitumor agent-183 has prolonged retention in the tumor tissues .
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-
-
- HY-113217S1
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|
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Cholesteryl oleate-d7-1 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .
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-
-
- HY-W040193S3
-
|
|
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1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d83 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].
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-
-
- HY-N2362S5
-
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|
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DL-Alanine- 15N is the 15N labeled DL-Alanine[1]. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[2][3][4][5][6][7].
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-
| Cat. No. |
Product Name |
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Classification |
-
- HY-W440835
-
|
DSPE-PEG(2000)-DBCO
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DBCO
|
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DSPE-PEG-DBCO, MW 2000 is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG-DBCO, MW 2000 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-155788
-
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|
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DBCO
|
|
DSPE-PEG-DBCO ammonium is the ammonium salt form of DSPE-PEG-DBCO. DSPE-PEG-DBCO ammonium is utilized in copper-free click chemistry through SPAAC conjugation with an azido-functionalized peptide ligand. DSPE-PEG-DBCO ammonium is applied in drug-delivery and nanoparticle research .
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-
- HY-W440834
-
|
|
|
Azide
|
|
DSPE-PEG-Azide, MW 5000 is a click chemistry reactive phospholipid polyPEG which forms lipid bilayer or micelles in an aqueous solution. The polymer can be used to prepare liposomes or nanoparticles used for delivering nutrients or therapeutic agents, for example mRNA or DNA vaccine. Reagent grade, for research use only.
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-
- HY-W440694
-
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|
|
Azide
|
|
Cholesterol-PEG-Azide (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. Cholesterol-PEG-Azide (MW 2000) can be reacted with alkyne via CuAAC or SPAAC click chemistry.
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-
- HY-P10680
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|
|
Azide
|
|
TFE-IDAtp1-LinA is a highly potent amphiphilic carrier, containing a trifluoroethyl-iminodiacetic acid analog of Stp. TFE-IDAtp1-LinA, formed nanoparticles with Cas9 RNP/ssDNA, achieved enhanced green fluorescent protein knockouts with an ED50 of 0.38 nM Cas9/sgRNA ribonucleoproteins (RNP) .
|
-
- HY-W440833
-
|
|
|
Azide
|
|
DSPE-PEG-Azide, MW 3400 is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelles formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form triazole bond. Reagent grade, for research use only.
|
-
- HY-W440832
-
|
DSPE-PEG(2000) Azide
|
|
Azide
|
|
DSPE-PEG-Azide (MW 2000) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery . DSPE-PEG-Azide (MW 2000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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| Cat. No. |
Product Name |
|
Classification |
-
- HY-141629
-
|
Sphingomyelin 16:0
|
|
Phospholipids
|
|
N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles .
|
-
- HY-148648
-
|
|
|
Cationic Lipids
|
|
Lipid 29 is an ionizable amino lipid. Lipid 29 can be used to form lipid nanoparticles .
|
-
- HY-158796
-
|
|
|
Cationic Lipids
|
|
L202 is an ionizable cationic lipid (pKa=6.04) that can be used for the study of mRNA and lipid nanoparticles .
|
-
- HY-159725
-
|
|
|
Cationic Lipids
|
|
BAmP-O16B is an ionizable cationic amino lipid that can be used to generate lipid nanoparticles (LNPs) .
|
-
- HY-W441014
-
|
DSPE-PEG2000-NHS
|
|
Pegylated Lipids
|
|
DSPE-PEG-NHS, MW 2000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
|
-
- HY-W040193
-
DSPC
4 Publications Verification
1,2-Distearoyl-sn-glycero-3-PC; 1,2-Distearoyl-sn-glycero-3-phosphorylcholine
|
|
Phospholipids
|
|
DSPC (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
|
-
- HY-134541
-
SM-102
Maximum Cited Publications
19 Publications Verification
|
|
Cationic Lipids
|
|
SM-102 is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 has higher transfection efficiency. SM-102 plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
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-
- HY-153187
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|
|
|
Cationic Lipids
|
|
LNP Lipid-4 (Compound 8-8) is a lipid compound. LNP Lipid-4 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-4 has potential applications in the transportation of biologically active substances .
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-
- HY-150241
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|
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Phospholipids
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|
DOPE-NHS is a linker. DOPE-NHS can be used for peptides to be conjugated to exosomes and possibly other membrane-based nanoparticles. DOPE-NHS can be used for drug delivery .
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-
- HY-W040193A
-
|
1,2-Distearoyl-sn-glycero-3-PC (Excipient); 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (Excipient)
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Emulsifiers
Liposomal Film-forming Agents
|
|
DSPC Excipient (1,2-Distearoyl-sn-glycero-3-phosphorylcholine) is a cylindrical-shaped lipid. DSPC Excipient is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system .
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-
- HY-46759
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|
|
|
Cationic Lipids
|
|
Genevant CL1 is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery [1][2].
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-
- HY-134541A
-
|
|
|
Emulsifiers
Liposomal Film-forming Agents
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|
SM-102 Excipient is an amino cationic lipid useful in the formation of lipid nanoparticles (LNPs). SM-102 Excipient has higher transfection efficiency. SM-102 Excipient plays an important role in the effectiveness of lipid nanoparticles (LNPs) in delivering mRNA therapeutics and vaccines .
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-
- HY-133952
-
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|
Cationic Lipids
|
|
7-Oxotridecanedioic acid is a biodegradable cationic lipid intermediate compound for lipid nanoparticles formation. 7-Oxotridecanedioic acid can be incorporated into a lipid particle for delivering active agents .
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-
- HY-141674
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|
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Pegylated Lipids
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DMG-PEG is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
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-
- HY-143700
-
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|
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Cationic Lipids
|
|
18:0 DAP can be used to formulate lipid nanoparticles (LNPs), which mRNA is encapsulated in their core .
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-
- HY-159717
-
|
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Cationic Lipids
|
|
Lipid 331 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 331 is a carrier for both siRNA and mRNA .
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-
- HY-159726
-
|
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Cationic Lipids
|
|
C10-200 is an ionizable cationic lipid that can be used to generate lipid nanoparticles (LNPs). C10-200 is used in the study of mRNA delivery .
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-
- HY-145794
-
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|
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Cationic Lipids
|
|
ZA3-Ep10 is a zwitterionic lipid used in lipid nanoparticles formulation for in vivo RNA delivery and non-viral CRISPR/Cas gene editing.
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-
- HY-159709
-
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|
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Cationic Lipids
|
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VL-422 is an ionizable cationic lipid that can be used for lipid nanoparticle (LNP) and drug delivery research .
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-
- HY-159716
-
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|
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Cationic Lipids
|
|
Lipid 50 (compound 50) is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid 50 is a carrier for both siRNA and mRNA .
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-
- HY-159715
-
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Cationic Lipids
|
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Lipid DIM1 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid DIM1 is a carrier for both siRNA and mRNA .
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-
- HY-159714
-
|
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Cationic Lipids
|
|
Lipid HTO12 is an ionizable lipid that can be used for the generation of lipid nanoparticles (LNPs). Lipid HTO12 is a carrier for both siRNA and mRNA .
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-
- HY-148033
-
|
N,N,N-Trimethylchitosan
|
|
Polymers
|
|
Trimethyl chitosan (N,N,N-Trimethylchitosan) is a water-soluble multifunctional polymer which is a Chitosan (HY-B2144A) derivative. Trimethyl chitosan can be used for drug delivery and to synthesize nanoparticles .
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-
- HY-138170
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Cationic Lipids
|
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ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
|
-
- HY-153376
-
|
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Cationic Lipids
|
|
LNP Lipid-6 (Compound Lipid 5) is an ionizable lipid (amino lipid). LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) .
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-
- HY-153375
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|
|
Cationic Lipids
|
|
LNP Lipid-5 (Compound Lipid 2) is an ionizable lipid (amino lipid). LNP Lipid-5 can be used to prepare lipid nanoparticles (LNP) .
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-
- HY-138170A
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|
|
Emulsifiers
Liposomal Film-forming Agents
|
|
ALC-0315 Excipient is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 Excipient can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine .
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-
- HY-160045
-
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Aptamers
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|
AP1153 aptamer sodium is a DNA aptamer that specifically binds to the cholecystokinin receptor CCKBR (Kd: ~15 pM), but does not activate CCKBR-related signaling pathways. AP1153 aptamer sodium is internalized by pancreatic ductal adenocarcinoma (PDAC) cells in a receptor-mediated manner. AP1153 aptamer sodium can bioconjugate to the surface of fluorescent nanoparticles to facilitate nanoparticle delivery to PDAC tumors in vivo .
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-
- HY-160439
-
|
|
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Cationic Lipids
|
|
Ionizable lipid-2 (compound 1) is an ionizable lipid used for nucleic acid delivery and construct lipid nanoparticles (LNPs) .
|
-
- HY-148363
-
|
|
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Cationic Lipids
|
|
Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .
|
-
- HY-151507
-
|
|
|
Cationic Lipids
|
|
306Oi10 is a branched ionizable lipid that can be used to construct lipid nanoparticles (LNPs) for delivering messenger RNA. The surface ionization of lipid nanoparticles is related to the effectiveness of mRNA delivery. The tail of 306Oi10 has a one-carbon branch, which provides it with stronger surface ionization compared to lipids with linear tails, thereby enhancing its mRNA delivery efficacy. 306Oi10 can be used in research related to mRNA delivery .
|
-
- HY-W440835
-
|
DSPE-PEG(2000)-DBCO
|
|
Pegylated Lipids
|
|
DSPE-PEG-DBCO, MW 2000 is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery . DSPE-PEG-DBCO, MW 2000 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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-
- HY-155902B
-
|
Maleimide-PEG-Hydroxy (MW 1000)
|
|
Polymers
|
|
Mal-PEG-OH (MW 1000) was used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-155902A
-
|
Maleimide-PEG-Hydroxy (MW 2000)
|
|
Polymers
|
|
Mal-PEG-OH (MW 2000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
|
-
- HY-155902
-
|
Maleimide-PEG-Hydroxy (MW 5000)
|
|
Polymers
|
|
Mal-PEG-OH (MW 5000) can be used as a macroinitiator to obtain amphiphilic diblock copolymers by ring-opening polymerization of LA. Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems. Nanoparticles encapsulate Triptolide (HY-32735), which can avoid the disadvantage of Triptolide’s poor water solubility and reduce its toxicity.
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- HY-W441002
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Phospholipids
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DSPE-succinic acid is a phophalipid capped with a carboxylic acid moiety. The carboxylic acid moiety is reactive with amine to from a stable amide linkage. DSPE-succinic acid can be used to prepare nanoparticles or liposomes for agent nanocarrier to deliver therapeutics .
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-
- HY-112752
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Cholesterol
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Gal-C4-Chol is a glycosylated cholesterol derivative. Gal-C4-Chol can be used as a ligand for asialoglycoprotein receptors (ASGPR) to prepare Galactosylated (Gal) liposomes. Gal-C4-Chol can be used to prepare simple lipid-based nanoparticles .
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-
- HY-125924
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DSPE-PEG-NH2, MW 2000 ammonium; DSPE-PEG(2000) Amine ammonium
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Pegylated Lipids
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|
DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents .
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-
- HY-112760
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|
DSPE-mPEG2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium
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Pegylated Lipids
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|
18:0 mPEG2000 PE sodium can be used for the preparation of stabilized nucleic acid-lipid particllipid particles (SNALPs). SNALPs represent some of the earliest and best functional siRNA-ABC nanoparticles described .
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-
- HY-112764
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Pegylated Lipids
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|
DMG-PEG 2000 is used?for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the?lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
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-
- HY-112764A
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Emulsifiers
Liposomal Film-forming Agents
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|
DMG-PEG Excipient is used?for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG Excipient is also used for the?lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
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-
- HY-157252
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Cationic Lipids
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CL4F8-6 is an ionizable cationic lipid with a pKa of 6.14. CL4F8-6 can be used in lipid nanoparticles (LNPs)-based mRNA therapeutics. CL4F8-6 LNPs carrying Cas9 mRNA and sgRNA could induce CRISPR-mediated gene knockdown in mice .
|
-
- HY-139306
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Cationic Lipids
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|
BAMEAO16B is a lipid nanoparticle. BAMEAO16B integrated with disulfide bonds, can efficiently deliver Cas9 mRNA and sgRNA into cells while releasing RNA in response to the reductive intracellular environment for genome editing. BAMEAO16B can be used for the research of gene editing .
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-
- HY-151508
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Cationic Lipids
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|
Diamino lipid DAL4 is diamino lipid for the preparation of lipid nanoparticles (LNPs) encapsulated with mRNAs encoding cytokines including IL-12, IL-27 and GM-CSF. Diamino lipid DAL4 delivers mRNA to tumor cells to exert anti-tumor activity .
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-
- HY-156985
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Cationic Lipids
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|
Lipid AX4 is an ionizable cationic lipid with the pKa of 6.89， and can be used the study for the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo .
|
-
- HY-W414069
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|
|
Cholesterol
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|
Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs). Thiocholesterol can be used for plasma membrane research and drug delivery .
|
-
- HY-160552
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Cationic Lipids
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|
244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels .
|
-
- HY-154974
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|
|
Cationic Lipids
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|
LNP Lipid-8 (11-A-M) is an ionizable lipid, which can be used for lipid nanoparticles (LNP) to deliver siRNA to T cells without targeting to ligands. LNP LIPs-8 loaded with GFP siRNA (siGFP), and significantly causes GFP gene silencing in mice model .
|
-
- HY-W145518
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|
Emulsifiers
Thickeners
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|
Pectin is a heteropolysaccharide, derived from the cell wall of higher plants. Pectin involves in the formation of nanoparticles as a delivery vehicle of agents. Pectin is also an adsorbent, a broad-spectrum antimicrobial agent that binds to bacteria toxins and other irritants in the intestinal mucosa, relieves irritated mucosa .
|
-
- HY-147081
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|
AGRO-100
|
|
Aptamers
|
|
AS 1411 (AGRO-100) is an oligonucleotide aptamer targeting nucleoproteins. AS 1411 inhibits tumor cell proliferation by affecting the activity of nucleoprotein-containing complexes and can be used as a carrier to precisely deliver nanoparticles, oligonucleotides and small molecules to cancer cells. AS 1411 reduces PRMT5 expression to inhibit tumor growth in DU145 prostate cancer cells. AS 1411 works by blocking the binding of nucleoproteins to bcl-2 mRNA in MCF-7 breast cancer cells. AS 1411-coupled Jin nanospheres can inhibit breast cancer cell proliferation in vitro and in mouse models, has the ability to cross the blood-brain barrier with low tissue toxicity .
|
- HY-144012A
-
|
16:0 PEG350 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
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|
Pegylated Lipids
|
|
DPPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144012B
-
|
16:0 PEG550 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
|
Pegylated Lipids
|
|
DPPE-PEG550 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155926
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|
14:0 PEG750 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
|
Pegylated Lipids
|
|
DMPE-PEG750 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155931
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|
DOPE-PEG550; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
|
Pegylated Lipids
|
|
18:1 PEG550 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144013H
-
|
DSPE-mPEG5000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
|
Pegylated Lipids
|
|
18:0 mPEG5000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144013B
-
|
DSPE-mPEG550 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
|
Pegylated Lipids
|
|
18:0 mPEG550 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144012C
-
|
16:0 PEG750 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
|
Pegylated Lipids
|
|
DPPE-PEG750 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155924
-
|
14:0 PEG350 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
|
Pegylated Lipids
|
|
DMPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155927
-
|
14:0 PEG1000 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
|
Pegylated Lipids
|
|
DMPE-PEG1000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144012E
-
|
16:0 PEG3000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
|
Pegylated Lipids
|
|
DPPE-PEG3000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144013A
-
|
DSPE-mPEG350 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
|
Pegylated Lipids
|
|
18:0 mPEG350 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144013D
-
|
DSPE-mPEG1000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
|
Pegylated Lipids
|
|
18:0 mPEG1000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155934
-
|
DOPE-PEG5000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
|
Pegylated Lipids
|
|
18:1 PEG5000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144012D
-
|
16:0 PEG1000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
|
Pegylated Lipids
|
|
DPPE-PEG1000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155933
-
|
DOPE-PEG3000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
|
Pegylated Lipids
|
|
18:1 PEG3000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155932
-
|
DOPE-PEG1000; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] ammonium
|
|
Pegylated Lipids
|
|
18:1 PEG1000 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144012H
-
|
16:0 PEG5000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
|
Pegylated Lipids
|
|
DPPE-PEG5000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155925
-
|
14:0 PEG550 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-550] ammonium
|
|
Pegylated Lipids
|
|
DMPE-PEG550 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144013E
-
|
DSPE-mPEG3000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
|
Pegylated Lipids
|
|
18:0 mPEG3000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155930
-
|
DOPE-PEG350; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-350] ammonium
|
|
Pegylated Lipids
|
|
18:1 PEG350 PE is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-144013C
-
|
DSPE-mPEG750 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-750] ammonium
|
|
Pegylated Lipids
|
|
18:0 mPEG750 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155929
-
|
14:0 PEG5000 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
|
|
Pegylated Lipids
|
|
DMPE-PEG5000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-155928
-
|
14:0 PEG3000 PE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-3000] ammonium
|
|
Pegylated Lipids
|
|
DMPE-PEG3000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
|
- HY-147332
-
|
|
|
Cationic Lipids
|
|
TCL053 is an ionizable lipid carrier and used to introduce active components, in particular nucleic acids, into cells with excellent efriciency. TCL053, together with DPPC (Dipalmitoylphosphatidylcholine), PEG-DMG (Polyethylene glycoldimyristoyl glycerol), and cholesterol, forms lipid nanoparticle (LNP) which is able to deliver Cas9 mRNA and sgRNA into skeletal muscle .
|
- HY-163044
-
|
|
|
Cationic Lipids
|
|
C12-SPM is a lipid that mediates siRNA delivery. C12-SPM has no significant cytotoxicity and can be used for research on hepatoviral diseases .
|
- HY-150115
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|
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Cationic Lipids
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|
Lipid 10 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
- HY-150118
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|
|
Cationic Lipids
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|
Lipid 8 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
- HY-150117
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|
|
Cationic Lipids
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|
Lipid 6 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
- HY-153378
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|
|
|
Cationic Lipids
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|
Lipid 15 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
- HY-150116
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|
|
|
Cationic Lipids
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|
Lipid 1 is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
- HY-134782
-
|
|
|
Cationic Lipids
|
|
OF-Deg-Lin is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
|
- HY-153377
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|
|
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Cationic Lipids
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|
Lipid 14 is a potent ionizable lipid and can be used to synthesize lipid nanoparticles (LNPs) .
|
- HY-153373
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|
|
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Cationic Lipids
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|
4A3-Cit is an ionizable lipid used for the generation of lipid nanoparticles (LNPs).
|
- HY-160705
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|
|
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Cationic Lipids
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|
PNI 132, an ionizable lipid derived from the patent WO2020252589A, is useful in the formulation of lipid nanoparticles.
|
- HY-142979
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|
|
|
Pegylated Lipids
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|
DSPE-PEG 2000 is a PEG-lipid that can be used to form micelles as nanoparticles for drug delivery .
|
- HY-153138
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|
|
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Cationic Lipids
|
|
FTT5 LLNs are functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing .
|
- HY-141892A
-
|
DSPE PEG(2000) Carboxylic Acid sodium
|
|
Pegylated Lipids
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|
DSPE-PEG Carboxylic acid (sodium), MW 2000 is a PEG-lipid that can be used in the preparation of drug delivery nanoparticles .
|
- HY-112755
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|
|
|
Cationic Lipids
|
|
DODMA is a cationic lipid that can be used to prepare lipid nanoparticles. DODMA can be used for drug delivery .
|
- HY-160908
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|
|
|
Cationic Lipids
|
Lipid 88 is an ionizable cationic lipid. Lipid 88 can be used to synthesize lipid nanoparticles and deliver mRNA .
|
- HY-W800783
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|
CDESA
|
|
Cationic Lipids
|
|
DSTAP chloride (CDESA) is a cationic lipid that used in the formation of lipid nanoparticles (LNPs). DORI chloride has high transfection efficiency .
|
- HY-159713
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|
|
|
Cationic Lipids
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|
Lipid R6 is a lipid molecule that can be used to synthesize liposomes and is the lipid component in lipid nanoparticle (LNP) systems.
|
- HY-160576
-
|
|
|
Phospholipids
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|
DNCA is a neutral lipid that can be used in the generation of lipid nanoparticles (LNPs). DNCA can be used in nucleic acid delivery .
|
- HY-160578
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|
N-Cholesteryl succinyl glucosamine
|
|
Cholesterol
|
|
Glucosamine Cholesterol (N-Cholesteryl succinyl glucosamine) is a glucosamine-based lipid conjugate, and can be used in the formation of lipid nanoparticles (LNPs) .
|
- HY-153372
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|
|
|
Cationic Lipids
|
|
93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs).
|
- HY-153186
-
|
|
|
Cationic Lipids
|
|
LNP Lipid-3 is an ionizable lipid extracted from patent WO2021113777A, and can be used for the generation of Lipid nanoparticles (LNPs).
|
- HY-W440931
-
|
|
|
Pegylated Lipids
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|
MPEG2000-DMG is a synthetic lipid comprised of polyPEG and dimyristoyl glycerol. It is used in the creation of lipid nanoparticles (LNPs) for mRNA vaccines.
|
- HY-W590548
-
|
|
|
Cationic Lipids
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|
ATX-001 is an ionizable cationic lipid. ATX-001 can be used in the formation of lipid nanoparticles (LNPs) for the delivery mRNA .
|
- HY-W590532
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|
|
|
Cationic Lipids
|
|
306-O12B is an ionizable cationic lipid used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA .
|
- HY-W598178
-
|
|
|
Cationic Lipids
|
|
93-O17O is a chalcogen-containing ionizable cationic lipidoid that used in the formation of lipid nanoparticles (LNPs) .
|
- HY-158867
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|
|
|
Cationic Lipids
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|
DOSPA hydrochlorid is a frequently utilized cationic lipid in the generation of Lipid Nanoparticles (LNPs) for the development of mRNA vaccines, including the COVID-19 vaccine.
|
- HY-153235
-
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|
mRNA
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COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing mRNA encoding COVID-19 Spike Protein , suitable for detection of RNA delivery, translation efficiency, cell viability, etc. COVID-19 Spike Protein is the novel coronavirus pneumonia spike protein located on the membrane surface. COVID-19 Spike Protein undertakes the functions of virus binding to host cell membrane receptors and membrane fusion, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design .
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- HY-W250183B
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Polyethylene glycol octadecyl ether (n～20)
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Pegylated Lipids
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Polyoxyethylene (20) stearyl ether (Polyethylene glycol octadecyl ether) is a polyethylene glycolated lipid surfactant that can be used in the formation and stabilization studies of nanoparticles .
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- HY-W590531
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Cationic Lipids
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80-O16B is an ionizable cationic lipid containing disulfide bonds that can be used to prepare lipid nanoparticles (LNP) .
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- HY-149167
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ATX 100
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Cationic Lipids
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ATX-0126 (Compound 2) is a Thiocarbamate-Based Ionizable Lipid. ATX-0126 can be used as an excipient in mRNA-encapsulating lipid nanoparticle .
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- HY-112756
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Pegylated Lipids
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PEG2000-DGG is a synthetic lipid. PEG2000-DGG can be used in lipid-based nanoparticle (LNP) delivery systems .
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- HY-153852
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Cationic Lipids
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1LNP Lipid-7 (Compound 7013) is a lipid. LNP Lipid-6 can be used to prepare lipid nanoparticles (LNP) and for drug delivery .
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- HY-46759A
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Cationic Lipids
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Genevant CL1 monohydrochloride is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery .
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- HY-W441012
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Pegylated Lipids
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DSPE-PEG-NHS, MW 600 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
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- HY-149156
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Cationic Lipids
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Lipid C24 is a cationic ionizable lipid, and can be used in the formation of lipid nanoparticles (LNPs). Lipid C24 can be used for research of delivery of nucleic acids .
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- HY-W441016
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Pegylated Lipids
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DSPE-PEG-NHS, MW 5000 is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine .
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- HY-W441015A
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Pegylated Lipids
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DSPE-m-PEG-NHS (MW 3400) is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.
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- HY-156630
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Cationic Lipids
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Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
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- HY-148830
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Cationic Lipids
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Piperazine-bis(ethyl octadeca-9,12-dienoate) is a cationic lipid extracted from patent WO2023036148A1, and can be used for the generation of Lipid nanoparticles (LNPs).
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- HY-156630A
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Cationic Lipids
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Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure .
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- HY-W591461
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Pegylated Lipids
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DSPE-PEG-COOH, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal carboxylic acid can react with primary amine groups to form a stable amide bond.
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- HY-W441021
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Phospholipids
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DSPE-Pyrene is a phospholipid molecule with polycyclic aromatic hydrocarbon, and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles. Pyrene is a fluorescent probe whose spectrum is sensitive to the polarity of its environment.
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- HY-153371
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Cationic Lipids
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50-C2-C9-4tail has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo.
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- HY-160580
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Cationic Lipids
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G1-OC2-K3-E10 is an ionizable lipid, and can be used for delivery of mRNA in lipid nanoparticles (LNPs) .
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- HY-160574
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Phospholipids
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CoPoP (cobalt porphyrin-phospholipid) is a palmitic acid (16:1) phosphatidyl choline-cobal porphyrin conjugate. CoPoP formulated into lipid nanoparticles (LNPs) have successfully been used for delivery and imaging applications [1][2].
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- HY-W440995
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Pegylated Lipids
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DOPE-PEG-Mal (MW 2000) is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. It is also reactive with thiol at pH 6.5 tp 7.5 to form a stable thioether bond.
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- HY-W590555
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Pegylated Lipids
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Thiol-PEG-DMG, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.
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- HY-W440719
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Pegylated Lipids
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Cholesterol-PEG-MAL (MW 2000) is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.
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- HY-156936
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Cationic Lipids
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RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .
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- HY-148049
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Cationic Lipids
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TT3 is an ionizable lipid-like materials for mRNA and CRISPR/Cas9 delivery .
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- HY-W590683
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Cationic Lipids
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9A1P9 is a multi-tail ionizable cationic phospholipid. 9A1P9 induces membrane destabilization. 9A1P9 can be used for CRISPR-Cas9 gene editing in mice .
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- HY-W591381
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DSG-PEG 2000
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Pegylated Lipids
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DSG-PEG is a type of polyethylene glycol grease. DSG-PEG can be used to prepare liposomes .
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- HY-W719862
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Cationic Lipids
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16:0 PDP PE belongs to a class of head group modified functionalized lipids. 16:0 PDP PE has been used in preparation of rhodamine high-density lipoprotein nanoparticle (Rh-HDL NP) synthesis.
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- HY-W440690
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Pegylated Lipids
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Cholesterol-PEG-Amine (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles.
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- HY-153737
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Cationic Lipids
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113-N16B is an ionizable cationic lipid used for the generation of lipid nanoparticles (LNPs). 113-N16B delivers mRNA preferentially to pulmonary endothelial cells.
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- HY-W440724
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Pegylated Lipids
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Cholesterol-PEG-Thiol (MW 3400) is an amphiphatic PEG derivative which forms micelles in water and can be used to prepare liposomes or nanoparticles for drug delivery system. The thiol moiety is reactive with maleimide to form a stable thioether bond.
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- HY-160577
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Cationic Lipids
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DOG-IM4 can be used to synthesize nanoparticles to deliver antigen-encoding nucleic acids. It could be used to try to target autoimmune diseases, rare blood or metabolic diseases, allergies, cancer or infectious diseases .
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- HY-W590681
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Cationic Lipids
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113-O12B is a disulfide bond-containing ionizable cationic lipidoid. 113-O12B can be used in that generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
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- HY-W440927
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Pegylated Lipids
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Stearic acid-PEG-NHS, MW 2,000 is an amphiphatic PEG polymer which forms micelles in an aqueous solution for drug-loaded nanoparticles. The NHS ester is reactive with amine to form a stable amide bond. Reagent grade, for research purpose.
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- HY-148855
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Cationic Lipids
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OF-C4-Deg-Lin is an ionizable lipid with varied linker lengths. OF-C4-Deg-Lin can be used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA .
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- HY-W440820
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Cationic Lipids
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Bis(bis(2-carboxyethyl)aminopropyl)methylamine is a symmetrical branched linker featuring three tertiary amines and four carboxylic acids. Each carboxylic acid is open to forming esters or amides. It can be used in developing lipid nanoparticles.
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- HY-W590679
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Cationic Lipids
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113-O16B is a disulfide bond-containing ionizable cationic lipidoid. 113-O16B has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA .
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- HY-139305
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Cationic Lipids
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CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response .
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- HY-107799
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Solvents
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Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .
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- HY-134781
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CKK-E12
1 Publications Verification
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Cationic Lipids
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CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based research. CKK-E12 is highly selective toward liver parenchymal cell in vivo,
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- HY-159675
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Cationic Lipids
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1-A-N is a lipid nanoparticle (LNP) used for in vivo delivery of siRNA. 1-A-N can regulate immune response by delivering siCD45 (siRNA targeting CD45) to T cells and silencing the CD45 gene .
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- HY-W440917
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG-FITC, MW 5000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
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- HY-W440915
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG-FITC, MW 2000 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
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- HY-W440916
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG-FITC, MW 3400 is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
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- HY-W800825
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Cationic Lipids
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Octadecanedioic Acid Mono-L-carnitine ester is a cationic lipid which may be used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Its terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond.
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- HY-W440921
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG-Rhodamine, MW 5000 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
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- HY-142981
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DODA
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Cationic Lipids
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Dioctadecylamine (DODA) is a secondary amine that has been shown to self-organize in plate-like structures in aqueous solution. Dioctadecylamine exhibits sufficiently hydrophobic properties of nanoparticles and good dispersibility in nonpolar solvent. Dioctadecylamine does not form a monolayer above pH 3.9 .
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- HY-W440920
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG-Rhodamine, MW 3400 is a phospholipid polyPEG with red fluorescent. The polymer can form lipid bilayer and be used to prepare nanoparticles or liposomes for targeted drug delivery. Rhodamine has maximum absorption at 570 nm and emission around 595 nm and can be easily traced using an imaging technique.
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- HY-153136
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Cationic Lipids
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LNP Lipid-1 (Method B) is a lipid compound. LNP Lipid-1 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-1 has potential applications in the transport of biologically active substances such as small molecule agents, proteins, and nucleic acids .
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- HY-W440910
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG-Cy3, MW 5000 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-W440909
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG-Cy3, MW 3400 is a phospholipid PEG polymer with Cy3 dye used in labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-W440706
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Pegylated Lipids
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Cholesterol-PEG-alcohol (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. The amine can react with an activated NHS ester to form a stable amide bond.
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- HY-151506
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Phospholipids
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Phospholipid PL1 is a phospholipid-derived nanoparticle, can deliver costimulatory receptor mRNA (CD137 or OX40) to T cells. Phospholipid PL1 could induce the activation of various immune cells, including T cells and dendritic cells (DCs) in order to boost antitumor immunity .
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- HY-W440913
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG-Cy5, MW 5000 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-W440912
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG-Cy5, MW 3400 is a PEG phospholipid with Cy5 dye used in protein/nucelic acid labeling and fluorescence microscopy. The polymer can self-assemble in aqueous solution to form micelles/lipid bilayer and used to prepare liposomes or nanoparticles for nutrients delivery such as mRNA or DNA vaccine.
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- HY-W440681
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Cationic Lipids
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C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).
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- HY-W440684
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Cationic Lipids
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C13-113-tetra tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tetra tail can be formulated into a lipid nanoparticle (LNP).
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- HY-W440683
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Cationic Lipids
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C13-112-tetra-tail is a cationic lipid-like compound containing a polar amino alcohol head group, four hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tetra-tail can be formulated into a lipid nanoparticle (LNP).
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- HY-152229
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Cationic Lipids
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G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery .
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- HY-W440682
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Cationic Lipids
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C13-113-tri tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a tertiary amine linker. C13-113-tri tail can be formulated into a lipid nanoparticle (LNP).
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- HY-W583869
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1-Stearoyl-2-Oleoyl-sn-glycero-3-PE; 18:0-18:1 PE; PE(18:0/18:1)
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Phospholipids
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1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipids that contains stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for in vitro delivery of mRNA or nuclear-targeted plasmid DNA.
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- HY-W440991
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Pegylated Lipids
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DOPE-PEG-Amine (MW 2000) is a polydisperse PEG covalently attached to a phospholipid. The polymer is an amphiphilic molecule with hydrophobic fatty acid chains and hydrophilic PEG head which enables lipid bilayer or micelle formation in water. The phospholipid PEG can be used to prepare liposome or nanoparticles for targeted drug delivery and is reactive with alkyne to form a triazole ring.
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- HY-W440694
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Pegylated Lipids
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Cholesterol-PEG-Azide (MW 2000) is a pegylated lipids which can be used for preparation of liposome or nanoparticle. The lipophilic moiety can encapsulate hydrophobic drugs whereas the hydrophilic PEG chain helps the overal water solubility of the micelles. Cholesterol-PEG-Azide (MW 2000) can be reacted with alkyne via CuAAC or SPAAC click chemistry.
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- HY-W440936
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Pegylated Lipids
Fluorescent Lipids
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Stearic acid-PEG-Rhodamine, MW 5000 is a fatty acid containing PEG polymer which can self assemble in an aqueous solution to form micelles. The polymer can be used to prepare nanoparticles for drug encapsulation. The red dye rhodamine can be easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
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- HY-W440935
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Pegylated Lipids
Fluorescent Lipids
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Stearic acid-PEG-Rhodamine, MW 3400 is a fatty acid containing PEG polymer which can self assemble in an aqueous solution to form micelles. The polymer can be used to prepare nanoparticles for drug encapsulation. The red dye rhodamine can be easily traced by fluorescence microscopy. Rhodamine has maximum absorption at 570 nm and emission around 595 nm.
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- HY-145411
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Pegylated Lipids
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PEG2000-C-DMG, a pegylated lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3′ untranslated region of transthyretin mRNA .
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- HY-W440938
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Pegylated Lipids
Fluorescent Lipids
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Stearic acid-PEG-FITC, MW 2000 is an amphiphatic polyPEG which can self assemble to form micelles in water. The polymer can be used to encapsulate therapeutic agent. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
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- HY-160554
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Cationic Lipids
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C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. C12-113 can also be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice .
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- HY-148842
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Cationic Lipids
Cationic Lipids
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C14-4 is an ionizable lipid utilized for the synthesis of lipid nanoparticles (LNPs). C14-4 enhances mRNA delivery, enabling the effective transport of mRNA to primary human T cells, which in turn induces functional protein expression. C14-4 demonstrates high transfection efficiency while maintaining low cytotoxicity .
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- HY-W440939
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Pegylated Lipids
Fluorescent Lipids
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Stearic acid-PEG-FITC, MW 3400 is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
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- HY-W591332
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Pegylated Lipids
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DMPE-mPEG, MW 2000 is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the other end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications.
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- HY-W440940
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Pegylated Lipids
Fluorescent Lipids
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Stearic acid-PEG-FITC, MW 5000 is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
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- HY-132141
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5-Propargylamino-dUTP
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Nucleotides and their Analogs
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5-PA-dUTP (5-Propargylamino-dUTP) is a C5-modified nucleotide and can be incorporated into DNA nanoparticles (DNPs) for photosensitizer delivery . 5-PA-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-158861
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G1-nPr-C14E
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Cationic Lipids
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C3-K2-E14 is a multi-ionizable amino-lipid featuring a central tertiary amine with two identical branches and an n-propyl group. Each branch features a propanamide linking to a branched amine, each with two C14 arms and a hydroxyl. Ionizable lipids such as this may be applied in the development of lipid nanoparticles for drug discovery.
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- HY-145405
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Cationic Lipids
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C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B .
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- HY-160269
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Pegylated Lipids
Fluorescent Lipids
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DSPE-PEG-Fluor 488,MW 2000 is a PEG-dye-lipid conjugate consisting of a DSPE phospholipid and a Fluor 488 dye. DSPE is a phospholipid that spontaneously forms micelles in a water medium, and Fluor 488 is a cyanine dye that is widely used in fluorescence microscopy. Fluor 488 has excitation and emission maxima at 499 nm and 520 nm. Polyethylene glycol lipids are commonly used for the stabilization of lipid nanoparticles .
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- HY-Y1365
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Emulsifiers
Disintegrants
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Gelatins is a non-toxic, non carcinogenic, biodegradable, and non irritating natural polymer derived from partial hydrolysis of collagen. Due to its strong liquid absorption and swelling ability, Gelatins has excellent hemostatic properties and can be used as a matrix material for the reduction, growth, and stability of metal nanoparticles. Gelatins can also be used for tumor cell culture and tumor therapy [1][2][3].
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- HY-153231
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mRNA
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eGFP mRNA-LNP is a lipid nanoparticle (LNP) containing eGFP mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .
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- HY-137500
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Cationic Lipids
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NT1-014B is a potent NT1-lipidoid encapsulated AmB (amphotericin B). NT1-014B dopes the NT-lipidoids into BBB-impermeable lipid nanoparticles (LNPs) gave the LNPs the ability to cross the BBB. NT1-014B enhances brain delivery through intravenous injection .
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- HY-159700
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Cationic Lipids
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AA3-DLin is an ionizable cationic lipid with a pKa value of 5.8. AA3-DLin is used to delivery mRNA combined with lipid nanoparticles (LNPs). AA3-DLin LNP COVID-19 vaccines encapsulating SARS CoV-2 spike mRNAs successfully induces strong immunogenicity in a BALB/c mouse model .
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- HY-112758
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Cationic Lipids
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DLin-KC2-DMA is an ionisable cationic lipid (pKa≈6) that is virtually non-toxic to antigen presenting cells (APCs). DLin-KC2-DMA produces significant siRNA-mediated gene silencing of GAPDH, when binds to lipid nanoparticles (LNP). DLin-KC2-DMA can be used in siRNA delivery studies .
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- HY-113217
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Cholesterol
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Cholesteryl oleate is an ester compound formed from Cholesterol (HY-N0322) and Oleic acid (HY-N1446), which is involved in lipid transport, storage and cell membrane formation in living organisms. Cholesteryl oleate may serve as a potential biomarker for prostate cancer. Cholesteryl oleate can also prepare cationic solid lipid nanoparticles (SLNs) for efficient gene silencing .
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- HY-112624B
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Dextran 70; Dextran D70; Dextran T70(MW 64000-76000)
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Polymers
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Dextran T70 (MW 70,000) is a complex carbohydrate polymer consisting of glucose molecules linked by glycosidic bonds. Dextran has excellent solubility in water, making it useful as a viscosity modifier or stabilizer in foods, paints and adhesives. In the biomedical field, dextran is often used as a plasma expander because of its ability to increase blood volume when administered intravenously. It can also be modified to create dextran-based drug delivery systems, such as targeted nanoparticles.
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- HY-W440832
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DSPE-PEG(2000) Azide
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Pegylated Lipids
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DSPE-PEG-Azide (MW 2000) is an azide containing lipid that can be used to form micelles as nanoparticles for drug delivery . DSPE-PEG-Azide (MW 2000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-145799
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Cationic Lipids
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5A2-SC8 is an ionizable amino lipid in lipid nanoparticles (LNPs) that shows high delivery potential and low in vivo toxicity, enabling efficient delivery of small RNAs such as siRNA and miRNA into tumor cells. 5A2-SC8 LNPs can confer a unique delivery fate of RNA within the liver, thereby changing the therapeutic outcomes in cancer models .
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- HY-153229
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mRNA
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Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing Firefly luciferase mRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. Luciferase is commonly used as a bioluminescent reporter gene for gene regulation and function studies. Firefly Luciferase mRNA will express firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Common luciferase are firefly luciferase and sea kidney luciferase .
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- HY-137499
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Cationic Lipids
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NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination .
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- HY-131119
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Dioctadecyldimethylammonium bromide; DODAB
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Cationic Lipids
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Dimethyldioctadecylammonium bromide is a synthetic cationic lipid commonly used in gene delivery and vaccine development. Also known as DODAB or DDAB, it consists of a positively charged ammonium head group and two long hydrophobic tails. These properties make it useful for forming liposomes and other lipid-based nanoparticles that can efficiently deliver genetic material into cells. In addition to its applications in biotechnology, DDAB is also used in surfactants, emulsifiers and fabric softeners. However, due to its potential toxicity and irritation, extreme care should be taken when handling DDAB.
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- HY-148775
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Polymers
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PLGA-PEG-MAL (60kDA-3.4kDA, LA:GA ratio 75:25) is a kind of poly(lactide-co-glycolide)-block-poly(ethylene glycol) (PLGA-PEG-Mal) nanoparticles. PLGA-PEG-MAL (60kDA-3.4kDA, LA:GA ratio 75:25) has a molecular weight of 60kDA to 3.4kDA and contains a 75:25 ratio of lactic acid (LA) to glycolic acid (GA) molecules .
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- HY-153233
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mRNA
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CD19 car mRNA (Mouse)-LNP is a lipid nanoparticle (LNP) containing CD19 car mRNA, suitable for detection of RNA delivery, translation efficiency, cell viability, etc. CD19 car mRNA can be used in chimeric antigen receptor T cell immunotherapy (CAR-CD19). The CD19 car is a chimeric antigen receptor. Among them, CD19 is a CD molecule expressed by B cells (i.e. leukocyte differentiation antigen), an important membrane antigen involved in B cell proliferation, differentiation, activation and antibody production, and can also promote BCR signal transduction .
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- HY-148776
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Polymers
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PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 50:50) is a kind of poly(lactide-co-glycolide)-block-poly(ethylene glycol) (PLGA-PEG-Mal) nanoparticles. PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 50:50) has a molecular weight of 20kDA to 5.0kDA and contains a 50:50 ratio of lactic acid (LA) to glycolic acid (GA) molecules. The molecular ratio of LA to GA determines the rate of matrix degradation and protein re-release .
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- HY-159746
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Adjuvant
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HS801 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159748
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Adjuvant
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M402 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159754
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Adjuvant
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HS201 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159753
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Adjuvant
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HS105 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159752
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Adjuvant
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HS103 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159749
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Adjuvant
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M902 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159743
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Adjuvant
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M101 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159751
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Adjuvant
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HS101 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159744
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Adjuvant
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M103 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159747
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Adjuvant
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M401 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159750
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Adjuvant
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M903 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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- HY-159745
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Adjuvant
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M107 is a vaccine adjuvant and a key component in vaccines. Adjuvants can be divided into immunostimulants and delivery systems. Adjuvants can not only enhance the intensity and durability of immune responses, but also affect the type of immune responses. On the one hand, immunostimulants promote the production of antigen signals and co-stimulatory signals by targeting Toll-like receptors (TLRs) and other pattern recognition receptors (PRRs), leading to the maturation and activation of antigen presenting cells (APCs), thereby enhancing adaptive immune responses; on the other hand, delivery systems are carrier materials that promote antigen delivery by prolonging the bioavailability of loaded antigens and targeting antigens to lymph nodes or APCs. Several common adjuvants include: saponins, TLRs agonists, polysaccharides, nanoparticles, cytokines, and mucosal adjuvants .
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![1,1′,1′′,1′′′-[1,4-Piperazinediylbis(2,1-ethanediylnitrilo)]tetrakis[2-dodecanol]](http://file.medchemexpress.eu/product_pic/hy-112773.gif)
