Search Result

Results for "

Coumarins

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Aminoacyl-tRNA Synthetase (1) AMPK (4) Antibiotic (3) Apoptosis (18) Autophagy (2) Bacterial (27) Bcl-2 Family (2) Biochemical Assay Reagents (4) Cannabinoid Receptor (1) Carbonic Anhydrase (4) Caspase (3) Cathepsin (1) Cholinesterase (ChE) (8) COX (5) Cytochrome P450 (4) DNA/RNA Synthesis (4) EGFR (2) Endogenous Metabolite (11) ERK (5) Ferroptosis (1) Fluorescent Dye (33) Fungal (17) Glucosidase (2) Glutathione Peroxidase (1) Glutathione S-transferase (1) HCV Protease (1) HDAC (1) HIV (2) Influenza Virus (4) Interleukin Related (1) Isotope-Labeled Compounds (6) JNK (2) Keap1-Nrf2 (2) Lactate Dehydrogenase (1) Lipoxygenase (5) MAGL (1) Methylenetetrahydrofolate Dehydrogenase (MTHFD) (2) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) MMP (2) Monoamine Oxidase (3) Monocarboxylate Transporter (1) mTOR (2) NO Synthase (2) Oxidative Phosphorylation (1) p38 MAPK (5) PAI-1 (2) Parasite (4) PARP (2) Phosphatase (2) Phosphodiesterase (PDE) (3) Phospholipase (1) PKA (2) PKC (2) Reactive Oxygen Species (3) Sirtuin (2) TGF-beta/Smad (1) Toll-like Receptor (TLR) (2) TRP Channel (1) Tyrosinase (2)
By Research Areas:	Cancer (62) Cardiovascular Disease (9) Endocrinology (3) Infection (39) Inflammation/Immunology (41) Metabolic Disease (16) Neurological Disease (26)
Click Chemistry:	Labeling and Fluorescence Imaging (6) TCO (3) BCN (2) Tetrazine (1) Alkynes (1)

299

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

196

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0709R

Coumarin (Standard)	Bacterial Fungal	Infection Neurological Disease Inflammation/Immunology Cancer
Coumarin (Standard) is the analytical standard of Coumarin. This product is intended for research and analytical applications. Coumarin is a potent and orally active anti-inflammatory agent. Coumarin shows an antinociceptive effect. Coumarin shows antibacterial, antifungal and anticancer activity .

HY-N4273

Oxyimperatorin (±)-Heraclenin	Others	Others
Oxyimperatorin ((±)-Heraclenin) is a coumarin isolated from Angelica dahurica.

HY-126829

Coumarin-SAHA	HDAC	Cancer
Coumarin-SAHA is a fluorescent probe for determining the binding affinities (k_d) and the dissociation off-rates (k_off) of the HDAC8-inhibitor complexes .

HY-W110772

Coumarin153 Coumarin 540A	Others	Others
Coumarin153 is a coumarin. Coumarin153 can used as a fluorescence probe of Na dodecyl sulfate and cetyltrimethylammonium bromide .

HY-W077359

7-(Dimethylamino)-4-methylcoumarin	Others	Others
7-(Dimethylamino)-4-methylcoumarin is a coumarin. 7-(Dimethylamino)-4-methylcoumarin can be used in study coumarin fluorescent brightener solution .

HY-D2099

Coumarin-PEG2-SCO	Fluorescent Dye	Others
Coumarin-PEG2-SCO, a Coumarin (HY-N0709) deravitive, is a fluorescent dye, and can be used for labeling of small molecules and biomolecules .

HY-137933

5,6,7-Trimethoxycoumarin	Others	Others
5,6,7-Trimethoxycoumarin is a coumarin that can be isolated from Artemisia apiacea .

HY-N10029

Edgeworoside C	Others	Others
Edgeworoside C (compound 5) is a coumarin isolated from the flower buds of Edgeworthia chrysantha .

HY-N9531

3'-Hydroxyxanthyletin	Bacterial	Infection
3'-Hydroxyxanthyletin is a coumarin compound with antimycobacterial activities .

HY-N8791

Qianhucoumarin G	Others	Others
Qianhucoumarin G is a natural coumarin derivative found in Ligustici Radix .

HY-N4273R

Oxyimperatorin (Standard)	Others	Others
Oxyimperatorin (Standard) is the analytical standard of Oxyimperatorin. This product is intended for research and analytical applications. Oxyimperatorin ((±)-Heraclenin) is a coumarin isolated from Angelica dahurica.

HY-N8817

Decuroside V	Others	Others
Decuroside V is a coumarin-glycoside found in a Chinese agent “Qian-Hu” .

HY-N8632

Qianhucoumarin A	Others	Others
Qianhucoumarin A is a natural coumarin compound found in the roots of Peucedanum praeruptorum Dunn .

HY-N10169

Edgeworin	Others	Others
Edgeworin is a coumarin compound can be isolated from the root and stem of Edgeworthia .

HY-N7689

Mexoticin	Others	Others
Mexoticin is a naturally occurring coumarin that can be isolated from the leaves of Murraya omphalocarpa .

HY-N0947

(-)-Anomalin (-)-Praeruptorin B	Others	Inflammation/Immunology
(-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of Angelica anomala .

HY-N8712

Umckalin	Others	Others
Umckalin is a oxygenated coumarin from Pelargonium sidoides .

HY-N2775

8-Hydroxy-5-O-beta-D-glucosylpsoralen	Others	Others
8-Hydroxy-5-O-beta-D-glucosylpsoralen is a natural coumarin glucoside .

HY-N9532

Isobyakangelicol Anhydrobyakangelicin	Others	Cancer
Isobyakangelicol is a coumarin that can be found in the roots of Angelica dahurica. Isobyakangelicol inhibits the growth of HeLa and HepG2 cells, with IC₅₀s of 70.04 μM and 17.97 μM .

HY-N3258

Micromelin Micromelumin	Others	Others
Micromelin is a coumarin from Micromelum minutum (Forst. f.) Seem (family Rutaceae) .

HY-N11791

Qianhucoumarin B	Others	Others
Qianhucoumarin B is a coumarin derivative. Qianhucoumarin B can be isolated from from the traditional Chinese medicine Qianhu, roots of Peucedanum praeruptorum .

HY-W072009

5,7-Dihydroxycoumarin 5,7-dihydroxychromen-2-one	Bacterial	Infection
5,7-Dihydroxycoumarin is a coumarin isolated from the inflorescences of Macaranga triloba. 5,7-Dihydroxycoumarin has antibacterial activities .

HY-N2811

Acetyldihydromicromelin A	Others	Others
Acetyldihydromicromelin A is a coumarin isolated from the leaves of Micromelum integerrimum .

HY-D0078

DCIA	Fluorescent Dye	Others
DCIA is a fluorescent dye. DCIA contains a coumarin fluorophore and conjugates specifically with free cysteines in the protein .

HY-N2910

Auraptenol	Others	Others
Auraptenol is a coumarin that can be isolated from the leaves of Murraya paniculata .

HY-N0947R

(-)-Anomalin (Standard)	Others	Inflammation/Immunology
(-)-Anomalin (Standard) is the analytical standard of (-)-Anomalin. This product is intended for research and analytical applications. (-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of Angelica anomala .

HY-N10662

Angelicone Glabralactone	Others	Others
Angelicone (Glabralactone) is a coumarin. Angelicone can be isolated from Fatoua villosa .

HY-N3986

Hainanmurpanin	Others	Others
Hainanmurpanin is a coumarin that can be isolated from the aerial parts of Murraya paniculata .

HY-148937

Oroselol	Others	Others
Oroselol is a coumarin commonly found in a variety of plants, especially in the roots of angelica plants and the bark of cinnamon trees. Oroselol has potential medicinal properties, including anti-inflammatory, antioxidant and anti-tumor effects. Oroselol can be used in the production of fragrances, flavors and medicines

HY-N7672

Isoeuphorbetin	HCV Protease	Infection
Isoeuphorbetin, a dimeric coumarin isolated from Viola philippica, is a potent HCV protease inhibitor with an IC₅₀ of 3.63 µg/mL .

HY-121770

Rutarin	Others	Others
Rutarin is a Coumarin (HY-N0709) derivative, that can be isolated from the aerial parts of the plant Atalantta racemosa .

HY-N8712R

Umckalin (Standard)	Others	Others
Umckalin (Standard) is the analytical standard of Umckalin. This product is intended for research and analytical applications. Umckalin is a oxygenated coumarin from Pelargonium sidoides .

HY-N8340

Luvangetin	Others	Others
Luvangetin is a coumarin that can be isolated from Zanthoxylum avicennae .

HY-N9630

Qianhucoumarin C	Others	Others
Qianhucoumarin C is a coumarin derivative, which can be isolated from the roots of Peucedanum praeruptorum. Qianhuoumarin C has been studied for potential medicinal properties, including anti-inflammatory, antioxidant and anticancer effects. Qianhucoumarin C is an important ingredient in a variety of industrial processes, especially in the production of pharmaceuticals and herbal medicines .

HY-N2984

Calanolide E	Bacterial	Infection
Calanolide E is a natural coumarin with weakly inhibitory towards the Bacilli strains with MIC values ranging from 0.25-0.50 mg/mL .

HY-N3180

Norbraylin	Phosphodiesterase (PDE)	Inflammation/Immunology
Norbraylin, a natural prenylated coumarin, is a PDE4D2 inhibitor with an IC₅₀ value of 7.15 μM .

HY-149828

MTHFD2-IN-4	Methylenetetrahydrofolate Dehydrogenase (MTHFD)	Cancer
MTHFD2-IN-4, tricyclic coumarin derivative, is a potent MTHFD2 inhibitor. MTHFD2-IN-4 can be used in research of cancer .

HY-149828A

MTHFD2-IN-4 sodium	Methylenetetrahydrofolate Dehydrogenase (MTHFD)	Cancer
MTHFD2-IN-4 sodium, tricyclic coumarin derivative, is a potent MTHFD2 inhibitor. MTHFD2-IN-4 sodium can be used in research of cancer .

HY-N5092

7-Methylcoumarin	Others	Metabolic Disease
7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

HY-N1278

Selinidin Secryptotaenin A	Others	Others
Selinidin is a coumarin that can be isolated from Selinum vaginatum clarke .

HY-N8131

Pangelin	Bacterial	Infection Cancer
Pangelin is a coumarin that can be found in Ducrosia anethifolia. Pangelin exhibits anti-mycobacterial and anti-tumor activities .

HY-W140869

3-Acetyl-6-bromocoumarin	Others	Others
3-Acetyl-6-bromocoumarin is a coumarin. 3-Acetyl-6-bromocoumarin exhibites potent antioxidant activity at 56% .

HY-N2958

Braylin	Phosphodiesterase (PDE)	Inflammation/Immunology
Braylin, a coumarin, is a potent phosphodiesterase-4 (PDE4) inhibitor and is involved in anti-inflammatory and immunomodulation, which may serve as a potential target for the study of immunoinflammatory diseases .

HY-N9206

Kimcuongin	Others	Cardiovascular Disease
Kimcuongin (compound 1)is a coumarin that can be found in Murraya paniculata. Kimcuongin shows vasorelaxant activity with an IC₅₀ value of 37.7 μM. Kimcuongin can be used as a vasodilator .

HY-N3320

Marmin	Others	Neurological Disease
Marmin is a coumarin, that can be isolated from the immature bark of Aegle marmelos Correa. Marmin antagonizes the Histamine (HY-B1204)-induced contraction in competitive manner .

HY-N7252

Daphnin	Bacterial	Infection
Daphnin is one of the major coumarin bioactive components with antibacterial activity. Daphnin is isolated from the whole herb of Daphne odora (Thunb.), which is a folk medicine in China for the relief of fever .

HY-N10978

(-)-8-Methoxyobliquin	Others	Others
(-)-8-Methoxyobliquin is a coumarin that can be extracted from the aerial parts of Helianthus heterophyllus .

HY-D0039

3-Cyanoumbelliferone	Fluorescent Dye	Others
3-Cyanoumbelliferone is a coumarin derivative, acting as molecular probe and fluorescent dye. 3-Cyanoumbelliferone is also a macrophage migration inhibitory factor (MIF) tautomerase inhibitor with a K_i of 2.9 μM .

HY-W267897

7-Benzyloxy-4-(trifluoromethyl)coumarin 7-BFC	Cytochrome P450	Others
7-Benzyloxy-4-(trifluoromethyl)coumarin (7-BFC) is a coumarin fluorescent substrate. 7-Benzyloxy-4-(trifluoromethyl)coumarin is a substrate for cDNA-expressed CYP1A2 and CYP3A4 and is metabolized to 7-hydroxy-4-trifluoromethylcoumarin (HFC). 7-Benzyloxy-4-(trifluoromethyl)coumarin is used for rapid CYP isoform metabolism and inhibition screening studies .

HY-N3086

Phebalosin	Others	Others
Phebalosin is a coumarin that can be isolated from Polygala paniculata. Phebalosin shows biological activity but very unstable in aqueous solution .

Cat. No.	Product Name

HY-L0107V

Life Chemicals Natural Product-like Compound Library

13,236 compounds

Natural products are small molecules produced naturally by any organism including primary and secondary metabolites. Nowadays, new drugs based on Natural products are successfully applied to treat tumors, viral and bacterial diseases, and nervous disorders. In response to the current drug discovery demand, we created this natural product-like compound library with 13,236 in-stock synthetic compounds similar to natural ones. The library was designed by 2D fingerprint similarity filtering, chemical descriptor-based and natural-likeness scoring selection. These compounds are useful tools for high throughput screening (HTS) and high content screening (HCS) programs.

Cat. No.	Product Name	Type

HY-D0078

DCIA	Fluorescent Dyes/Probes
DCIA is a fluorescent dye. DCIA contains a coumarin fluorophore and conjugates specifically with free cysteines in the protein .

HY-101887

Calcein Blue 1 Publications Verification	Fluorescent Dyes/Probes
Calcein Blue, a membrane-impermeant fluorescent dye, is a coumarin derivative that contains an iminodiacetic acid structure. Calcein Blue is also a metallofluorochromic indicator .

HY-W027544

MCA	Fluorescent Dyes/Probes
MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .

HY-121930

Coumarin 6H	Fluorescent Dyes/Probes
Coumarin 6H, a Coumarin (Coumarin (HY-N0709)) derivative, is a laser dye. The fluorescence emission of Coumarin 6H can be enhanced by hydrogen bonding interactions .

HY-D0027

7-Amino-4-methylcoumarin

Coumarin 120; AMC

Fluorescent Dyes/Probes

7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively.

HY-D2099

Coumarin-PEG2-SCO	Dyes
Coumarin-PEG2-SCO, a Coumarin (HY-N0709) deravitive, is a fluorescent dye, and can be used for labeling of small molecules and biomolecules .

HY-D0066

7-Diethylaminocoumarin-3-carbohydrazide DCCH	Dyes
7-Diethylaminocoumarin-3-carbohydrazide is a coumarin. 7-Diethylaminocoumarin-3-carbohydrazide can be used to detect sugar chains and quantify biological carbonyl compounds .

HY-D0092

7-Ethoxy-4-methylcoumarin	Fluorescent Dyes/Probes
7-Ethoxy-4-methylcoumarin is a coumarin derivative and can be used as a substrate probe of mammalian cytochromes P450 1A1, 2B4 and 2B6 .

HY-D0092R

7-Ethoxy-4-methylcoumarin (Standard)	Fluorescent Dyes/Probes
7-Ethoxy-4-methylcoumarin (Standard) is the analytical standard of 7-Ethoxy-4-methylcoumarin. This product is intended for research and analytical applications. 7-Ethoxy-4-methylcoumarin is a coumarin derivative and can be used as a substrate probe of mammalian cytochromes P450 1A1, 2B4 and 2B6 .

HY-D2157

Coumarin 343 X NHS ester Coumarin 343-aminohexanoic acid-NHS ester	Fluorescent Dyes/Probes
Coumarin 343 X NHS ester is a homologue of Coumarin 343 (HY-W267364). Coumarin 343 is a hydrophilic fluorescent probe for use in microfluids.

HY-W324391

Coumarin 106 Coumarin 478	Dyes
Coumarin 106 (Coumarin 478) is a dipolar laser dye. Coumarin 106 is an inhibitor of AChE and BChE. Coumarin 106 displays mixed-type AChE inhibition with a pIC₅₀=4.97 and K_i=2.36 μM. Coumarin 106 inhibits BChE with slightly lower potency (pIC₅₀=4.56) .

HY-125750

Coumarin 7	Protein Labeling
Coumarin 7 is a coumarin laser dye in plants in the form of glycosides .

HY-D0027R

7-Amino-4-methylcoumarin (Standard)

Fluorescent Dyes/Probes

7-Amino-4-methylcoumarin (Standard) is the analytical standard of 7-Amino-4-methylcoumarin. This product is intended for research and analytical applications. 7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively. [4]

HY-156302

Coumarin-PEG2-endoBCN	Dyes
Coumarin-PEG2-endoBCN is a fluorescent dye containing a coumarin fluorophore and can be used as a click chemistry reagent .

HY-156304

Coumarin-C2-TCO	Fluorescent Dyes/Probes
Coumarin-C2-TCO is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.

HY-D0981

7-Amino-4-(trifluoromethyl)coumarin 1 Publications Verification Coumarin 151; AFC	Fluorescent Dyes/Probes
7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a fluorescent marker for the sensitive detection of proteinases. The excitation and emission wavelengths are 400 and 490 nm, respectively.

HY-156303

Coumarin-PEG2-TCO	Fluorescent Dyes/Probes
Coumarin-PEG2-TCO is a dye derivative of Coumarin (HY-N0709) containing 2 PEG units. Coumarin-PEG2-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.

HY-156306

Coumarin-PEG3-TCO	Fluorescent Dyes/Probes
Coumarin-PEG3-TCO is a dye derivative of Coumarin (HY-N0709) containing 3 PEG units. Coumarin-PEG3-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.

HY-156309

Coumarin-PEG8-tetrazine	Fluorescent Dyes/Probes
Coumarin-PEG8-tetrazine is a dye derivative of Coumarin (HY-N0709) containing 8 PEG units. Coumarin-PEG8-tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-156305

Coumarin-C2-exo-BCN	Fluorescent Dyes/Probes
Coumarin-C2-exoBCN is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-exoBCN contains the lyophilic bidentate macrocyclic ligand exo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to generate stable triazoles under catalyst-free conditions.

HY-W027857

Coumarin 314	Dyes
Coumarin 314 is a dye which has an intense absorption in the visible and additionally presents a large solvent dependence .

HY-W267393

4,6-Dimethyl-7-ethylaminocoumarin	Dyes
4,6-Dimethyl-7-ethylaminocoumarin is a laser dye for pulse and continuous operation .

HY-124197

Coumarin hydrazine	Fluorescent Dyes/Probes
Coumarin hydrazine is a fluorescent chemical probe (λ_ex=420–450/λ_em=468nm) to label cellular protein- and lipid-bound carbonyls .

HY-162075

RF16	Fluorescent Dyes/Probes
RF16 is a fluorescent macromolecular material. RF16 precisely retains in cells to track IRE1-Halo protein with the HaloTag ligand .

HY-137845

4-Methylumbelliferyl β-D-galactopyranoside 1 Publications Verification	Fluorescent Dyes/Probes
4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase which, when cleaved, produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer .

HY-D2266

FluoBar1	Fluorescent Dyes/Probes
FluoBar1 is an imaging fluorescence probe modified by a barbiturate ligand with fluorescent coumarin. FluoBar1 can monitor L-type voltage-gated calcium channels (LTCC) in living cells in real time for the study of neurological diseases .

HY-N7131

Coumarin 6 Maximum Cited Publications 7 Publications Verification	Fluorescent Dyes/Probes
Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λ_exc=450 nm, λ_em=505 nm) .

HY-D1085

AMCA-X SE	Fluorescent Dyes/Probes
AMCA-X-SE is a coumarin derivative that generates fixed blue fluorescence and an NHS-activated ester that forms stable amide bonds with primary amine groups. It is used as a reactive dye for labeling amino groups of peptides, proteins, and oligonucleotides. Maximum excitation/emission wavelength: 354/442 nm .

HY-D0025

7-Amino-4-methylcoumarin-3-acetic acid	Fluorescent Dyes/Probes
7-Amino-4-methylcoumarin-3-acetic acid is a fluorescent protein labelling agent. 7-Amino-4-methylcoumarin-3-acetic acid emits in the blue region (440-460 nm) on activation with UV light (350 nm) .

HY-D0035

MPAC-Br	Fluorescent Dyes/Probes
MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .

HY-D0002

7-Amino-4-methylcoumarin hydrogensulfate

Coumarin 120 hydrogensulfate; AMC hydrogensulfate

Dyes

7-Amino-4-methylcoumarin hydrogensulfate (Coumarin 120 hydrogensulfate; AMC hydrogensulfate) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0709R

Coumarin (Standard)	Structural Classification Microorganisms Ambrosia psilostachya DC. Source classification Coumarins Phenylpropanoids Umbelliferae Plants	Bacterial Fungal
Coumarin (Standard) is the analytical standard of Coumarin. This product is intended for research and analytical applications. Coumarin is a potent and orally active anti-inflammatory agent. Coumarin shows an antinociceptive effect. Coumarin shows antibacterial, antifungal and anticancer activity .

HY-N4273

Oxyimperatorin (±)-Heraclenin	Chrysanthemum × morifolium (Ramat.) Hemsl. Classification of Application Fields Source classification Other Diseases Coumarins Phenylpropanoids Plants Umbelliferae Disease Research Fields	Others
Oxyimperatorin ((±)-Heraclenin) is a coumarin isolated from Angelica dahurica.

HY-137933

5,6,7-Trimethoxycoumarin	Structural Classification Natural Products Source classification Artemisia carvifolia Buch.-Ham. ex Roxb. Plants Compositae	Others
5,6,7-Trimethoxycoumarin is a coumarin that can be isolated from Artemisia apiacea .

HY-N10029

Edgeworoside C	Structural Classification Edgeworthia chrysantha Lindl. Thymelaeaceae Source classification Coumarins Phenylpropanoids Plants	Others
Edgeworoside C (compound 5) is a coumarin isolated from the flower buds of Edgeworthia chrysantha .

HY-N9531

3'-Hydroxyxanthyletin	Infection other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Disease Research Fields	Bacterial
3'-Hydroxyxanthyletin is a coumarin compound with antimycobacterial activities .

HY-N8791

Qianhucoumarin G	Structural Classification Chrysanthemum × morifolium (Ramat.) Hemsl. Source classification Coumarins Phenylpropanoids Plants Umbelliferae	Others
Qianhucoumarin G is a natural coumarin derivative found in Ligustici Radix .

HY-N4273R

Oxyimperatorin (Standard)	Structural Classification Chrysanthemum × morifolium (Ramat.) Hemsl. Source classification Coumarins Phenylpropanoids Umbelliferae Plants	Others
Oxyimperatorin (Standard) is the analytical standard of Oxyimperatorin. This product is intended for research and analytical applications. Oxyimperatorin ((±)-Heraclenin) is a coumarin isolated from Angelica dahurica.

HY-N8817

Decuroside V	Structural Classification other families Classification of Application Fields Source classification Other Diseases Coumarins Phenylpropanoids Plants Disease Research Fields	Others
Decuroside V is a coumarin-glycoside found in a Chinese agent “Qian-Hu” .

HY-N8632

Qianhucoumarin A	Structural Classification Chrysanthemum × morifolium (Ramat.) Hemsl. Source classification Coumarins Phenylpropanoids Plants Umbelliferae	Others
Qianhucoumarin A is a natural coumarin compound found in the roots of Peucedanum praeruptorum Dunn .

HY-N10169

Edgeworin	Structural Classification Edgeworthia chrysantha Lindl. Thymelaeaceae Source classification Coumarins Phenylpropanoids Plants	Others
Edgeworin is a coumarin compound can be isolated from the root and stem of Edgeworthia .

HY-N7689

Mexoticin	Classification of Application Fields Source classification Murraya paniculata (L.) Jack. Other Diseases Rutaceae Coumarins Phenylpropanoids Plants Disease Research Fields	Others
Mexoticin is a naturally occurring coumarin that can be isolated from the leaves of Murraya omphalocarpa .

HY-N0947

(-)-Anomalin (-)-Praeruptorin B	Structural Classification Classification of Application Fields Source classification Coumarins Salvia hypargeia Fisch. & C.A.Mey. Phenylpropanoids Umbelliferae Plants Inflammation/Immunology Disease Research Fields Artemisia vulgaris L.	Others
(-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of Angelica anomala .

HY-N8712

Umckalin	Monophenols Classification of Application Fields Source classification Other Diseases Coumarins Phenols Pelargonium hortorum Phenylpropanoids Plants Disease Research Fields Geraniaceae	Others
Umckalin is a oxygenated coumarin from Pelargonium sidoides .

HY-N2775

8-Hydroxy-5-O-beta-D-glucosylpsoralen	Structural Classification Source classification Coumarins Ageratina altissima (L.) R.M.King & H.Rob. Phenylpropanoids Plants Umbelliferae	Others
8-Hydroxy-5-O-beta-D-glucosylpsoralen is a natural coumarin glucoside .

HY-N9532

Isobyakangelicol Anhydrobyakangelicin	Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Umbelliferae Helogyne apaloidea Nutt. Disease Research Fields Cancer	Others
Isobyakangelicol is a coumarin that can be found in the roots of Angelica dahurica. Isobyakangelicol inhibits the growth of HeLa and HepG2 cells, with IC₅₀s of 70.04 μM and 17.97 μM .

HY-N3258

Micromelin Micromelumin	other families Classification of Application Fields Source classification Other Diseases Coumarins Phenylpropanoids Plants Disease Research Fields	Others
Micromelin is a coumarin from Micromelum minutum (Forst. f.) Seem (family Rutaceae) .

HY-N11791

Qianhucoumarin B	Structural Classification Chrysanthemum × morifolium (Ramat.) Hemsl. Source classification Coumarins Phenylpropanoids Plants Umbelliferae	Others
Qianhucoumarin B is a coumarin derivative. Qianhucoumarin B can be isolated from from the traditional Chinese medicine Qianhu, roots of Peucedanum praeruptorum .

HY-W072009

5,7-Dihydroxycoumarin 5,7-dihydroxychromen-2-one	Infection other families Classification of Application Fields Source classification Coumarins Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Macaranga triloba	Bacterial
5,7-Dihydroxycoumarin is a coumarin isolated from the inflorescences of Macaranga triloba. 5,7-Dihydroxycoumarin has antibacterial activities .

HY-N2811

Acetyldihydromicromelin A	other families Classification of Application Fields Source classification Other Diseases Coumarins Phenylpropanoids Plants Disease Research Fields	Others
Acetyldihydromicromelin A is a coumarin isolated from the leaves of Micromelum integerrimum .

HY-N2910

Auraptenol	Structural Classification Source classification Rutaceae Coumarins Phenylpropanoids Plants Murraya exotica L. Mant.	Others
Auraptenol is a coumarin that can be isolated from the leaves of Murraya paniculata .

HY-N0947R

(-)-Anomalin (Standard)	Structural Classification Source classification Coumarins Salvia hypargeia Fisch. & C.A.Mey. Phenylpropanoids Umbelliferae Plants Artemisia vulgaris L.	Others
(-)-Anomalin (Standard) is the analytical standard of (-)-Anomalin. This product is intended for research and analytical applications. (-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of Angelica anomala .

HY-N10662

Angelicone Glabralactone	Structural Classification Source classification Coumarins Phenylpropanoids Plants Umbelliferae Echinacea angustifolia DC.	Others
Angelicone (Glabralactone) is a coumarin. Angelicone can be isolated from Fatoua villosa .

HY-N3986

Hainanmurpanin	Structural Classification Source classification Rutaceae Coumarins Phenylpropanoids Plants Murraya exotica L. Mant.	Others
Hainanmurpanin is a coumarin that can be isolated from the aerial parts of Murraya paniculata .

HY-148937

Oroselol	Structural Classification Carlina acaulis L. Source classification Coumarins Phenylpropanoids Plants Umbelliferae	Others
Oroselol is a coumarin commonly found in a variety of plants, especially in the roots of angelica plants and the bark of cinnamon trees. Oroselol has potential medicinal properties, including anti-inflammatory, antioxidant and anti-tumor effects. Oroselol can be used in the production of fragrances, flavors and medicines

HY-N7672

Isoeuphorbetin	Infection Classification of Application Fields Gramineae Source classification Coumarins Phenols Polyphenols Leptochloa chinensis (Linn.) Nees Phenylpropanoids Plants Disease Research Fields	HCV Protease
Isoeuphorbetin, a dimeric coumarin isolated from Viola philippica, is a potent HCV protease inhibitor with an IC₅₀ of 3.63 µg/mL .

HY-121770

Rutarin	Structural Classification Source classification Rutaceae Coumarins Glycosmis pseudoracemosa (Guill.) Swinge Phenylpropanoids Plants	Others
Rutarin is a Coumarin (HY-N0709) derivative, that can be isolated from the aerial parts of the plant Atalantta racemosa .

HY-N8712R

Umckalin (Standard)	Structural Classification Monophenols Source classification Coumarins Phenols Pelargonium hortorum Phenylpropanoids Plants Geraniaceae	Others
Umckalin (Standard) is the analytical standard of Umckalin. This product is intended for research and analytical applications. Umckalin is a oxygenated coumarin from Pelargonium sidoides .

HY-N8340

Luvangetin	Structural Classification Natural Products Source classification Rutaceae Zanthoxylum avicennae (Lam.) DC. Plants	Others
Luvangetin is a coumarin that can be isolated from Zanthoxylum avicennae .

HY-N9630

Qianhucoumarin C	Structural Classification Natural Products Chrysanthemum × morifolium (Ramat.) Hemsl. Source classification Plants Umbelliferae	Others
Qianhucoumarin C is a coumarin derivative, which can be isolated from the roots of Peucedanum praeruptorum. Qianhuoumarin C has been studied for potential medicinal properties, including anti-inflammatory, antioxidant and anticancer effects. Qianhucoumarin C is an important ingredient in a variety of industrial processes, especially in the production of pharmaceuticals and herbal medicines .

HY-N2984

Calanolide E	Structural Classification Calophyllum wallichianum Planch. & Triana Source classification Coumarins Phenylpropanoids Plants Calophyllaceae	Bacterial
Calanolide E is a natural coumarin with weakly inhibitory towards the Bacilli strains with MIC values ranging from 0.25-0.50 mg/mL .

HY-N3180

Norbraylin	Toddalia asiatica (L.) Lam. Structural Classification Source classification Rutaceae Coumarins Phenylpropanoids Plants	Phosphodiesterase (PDE)
Norbraylin, a natural prenylated coumarin, is a PDE4D2 inhibitor with an IC₅₀ value of 7.15 μM .

HY-N5092

7-Methylcoumarin	Microorganisms Source classification Coumarins Metabolic Disease Phenylpropanoids Disease Research Fields	Others
7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

HY-N1278

Selinidin Secryptotaenin A	Structural Classification Source classification Coumarins Phenylpropanoids Plants Papaveraceae	Others
Selinidin is a coumarin that can be isolated from Selinum vaginatum clarke .

HY-N8131

Pangelin	Infection Structural Classification other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Disease Research Fields	Bacterial
Pangelin is a coumarin that can be found in Ducrosia anethifolia. Pangelin exhibits anti-mycobacterial and anti-tumor activities .

HY-N2958

Braylin	Source classification Rutaceae Plants Zanthoxylum tingoassuiba A.St.-Hil.	Phosphodiesterase (PDE)
Braylin, a coumarin, is a potent phosphodiesterase-4 (PDE4) inhibitor and is involved in anti-inflammatory and immunomodulation, which may serve as a potential target for the study of immunoinflammatory diseases .

HY-N9206

Kimcuongin	Structural Classification Source classification Rutaceae Coumarins Phenylpropanoids Plants Murraya exotica L. Mant.	Others
Kimcuongin (compound 1)is a coumarin that can be found in Murraya paniculata. Kimcuongin shows vasorelaxant activity with an IC₅₀ value of 37.7 μM. Kimcuongin can be used as a vasodilator .

HY-N3320

Marmin	Structural Classification Source classification Rutaceae Coumarins Phenylpropanoids Plants Aegle marmelos (L.) Correa	Others
Marmin is a coumarin, that can be isolated from the immature bark of Aegle marmelos Correa. Marmin antagonizes the Histamine (HY-B1204)-induced contraction in competitive manner .

HY-N7252

Daphnin	Infection Structural Classification Monophenols other families Classification of Application Fields Source classification Coumarins Phenols Phenylpropanoids Plants Disease Research Fields	Bacterial
Daphnin is one of the major coumarin bioactive components with antibacterial activity. Daphnin is isolated from the whole herb of Daphne odora (Thunb.), which is a folk medicine in China for the relief of fever .

HY-N10978

(-)-8-Methoxyobliquin	Structural Classification Source classification Coumarins Phenylpropanoids Plants Compositae Albizia glaberrima (Schumach. & Thonn.) Benth.	Others
(-)-8-Methoxyobliquin is a coumarin that can be extracted from the aerial parts of Helianthus heterophyllus .

HY-N3086

Phebalosin	Structural Classification Polygala paniculata L. Source classification Polygalaceae Coumarins Phenylpropanoids Plants	Others
Phebalosin is a coumarin that can be isolated from Polygala paniculata. Phebalosin shows biological activity but very unstable in aqueous solution .

HY-N4287

Nordalbergin	Classification of Application Fields Leguminosae Source classification Coumarins Phenols Polyphenols Phenylpropanoids Dalbergia sissoo Plants Disease Research Fields Cancer	Others
Nordalbergin, a coumarin isolated from the wood bark of Dalbergia sissoo. Nordalbergin shows strong activity in the induction of differentiation of HL-60 .

HY-N0341

Scopolin	Structural Classification Classification of Application Fields Anisodus tanguticus (Maxinowicz) Pascher Source classification Coumarins Metabolic Disease Arabidopsis thaliana Phenylpropanoids Solanaceae Plants Brassicaceae Disease Research Fields	Sirtuin
Scopolin is a coumarin isolated from Arabidopsis thaliana (Arabidopsis) roots . Scopolin attenuated hepatic steatosis through activation of SIRT1-mediated signaling cascades .

HY-N5110

Marmesinin (-)-Marmesinin; Ammijin	Pseudognaphalium affine (D. Don) Anderberg Source classification Coumarins Phenylpropanoids Plants Umbelliferae	Others
Marmesinin ((-)-Marmesinin), a natural coumarin, is a biosynthetic precursor of psoralen and linear furanocoumarins. Marmesinin exhibits significant neuroprotective activities against glutamate-induced toxicity .

HY-N9535

tert-OMe-byakangelicin	Structural Classification Classification of Application Fields Source classification Coumarins Metabolic Disease Phenylpropanoids Umbelliferae Helogyne apaloidea Nutt. Plants Disease Research Fields	Others
tert-OMe-byakangelicin is a coumarin that can enhances the adrenaline-induced lipolytic effect and inhibits insulin-stimulated triglyceride synthesis from glucose in fat cells .

HY-N3102A

(E)-p-Coumaryl alcohol (E)-p-Hydroxycinnamyl alcohol	Structural Classification Monophenols Simple Phenylpropanols Source classification Phenols Alpinia officinarum Hance Phenylpropanoids Plants Zingiberaceae	Others
(E)-p-Coumaryl alcohol is a metabolite of coumarin that has significant cytotoxicity. (E)-p-Coumaryl alcohol can be isolated from Alpinia officinarum and Rhodiola rosea and can be used for inflammation research .

HY-N12548

Thamnosmonin	Structural Classification Source classification Coumarins Camellia japonica L. Phenylpropanoids Plants Theaceae	Others
Thamnosmonin is a coumarin that can be isolated from Sida acuta and Sida rhombifolia. Thamnosmonin has insecticidal activity .

HY-N5092R

7-Methylcoumarin (Standard)	Microorganisms Source classification Coumarins Phenylpropanoids	Others
7-Methylcoumarin (Standard) is the analytical standard of 7-Methylcoumarin. This product is intended for research and analytical applications. 7-Methylcoumarin, a coumarin, exhibits strong hepatoprotective activity and potent antioxidant effect .

HY-N7252R

Daphnin (Standard)	Structural Classification Monophenols other families Source classification Coumarins Phenols Phenylpropanoids Plants	Bacterial
Daphnin (Standard) is the analytical standard of Daphnin. This product is intended for research and analytical applications. Daphnin is one of the major coumarin bioactive components with antibacterial activity. Daphnin is isolated from the whole herb of Daphne odora (Thunb.), which is a folk medicine in China for the relief of fever .

HY-N0825

Nodakenin	Structural Classification Classification of Application Fields Source classification Coumarins Phenylpropanoids Umbelliferae Plants Inflammation/Immunology Disease Research Fields Bidens parviflora Willd.	Cholinesterase (ChE)
Nodakenin is a major coumarin glucoside in the root of Angelica decusiva. Nodakenin inhibits acetylcholinesterase (AChE) activity with an IC₅₀ of 84.7 μM .

HY-N2554

Osthenol Ostenol	Source classification Coumarins Phenols Polyphenols Phenylpropanoids Plants Umbelliferae Kleinia odora (Forssk.) DC.	Monoamine Oxidase
Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (K_i=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC₅₀ of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B .

Cat. No.	Product Name	Chemical Structure

HY-N0709S

Coumarin-d4
Coumarin-d₄ is the deuterium labeled Coumarin. Coumarin is the primary bioactive ingredient in Radix Glehniae, named Beishashen in China, which possesses many pharmacological activities, including anticancer, anti-inflammation and antivirus activities.

HY-W015551S

trans-2-Decenal-d2
trans-2-Decenal-d₂ is deuterated labeled Coumarin (HY-N0709). Coumarin is a potent and orally active anti-inflammatory agent. Coumarin shows an antinociceptive effect. Coumarin shows antibacterial, antifungal and anticancer activity .

HY-120201S

*7-Hydroxy Coumarin-d5 β-D-glucuronide sodium*
7-Hydroxy Coumarin-d₅ β-D-glucuronide (sodium) is the deuterium labeled 7-Hydroxy Coumarin β-D-glucuronide sodium[1].

HY-131126S

Metolcarb-d3
Metolcarb-d₃ is the deuterium labeled Herniarin. Herniarin is a natural coumarin occurs in some flowering plants, with antitumor effect.

HY-N0573S

Umbelliferone-d5
Umbelliferone-d₅ is the deuterium labeled Umbelliferone. Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.

HY-W027544S

(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d3
(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d₃ is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3].

HY-N0709S1

Coumarin-d6

Coumarin-d₆ is deuterated labeled trans-2-Undecenal (HY-W127505). Trans-2-UndecenalIt is an organic compound belonging to aldehydes. It has a strong, pungent smell and is commonly found in a variety of foods, including fruits and vegetables. Trans-2-UndecenalIt has a variety of applications in the flavor and fragrance industry, especially as a fragrance agent in products such as perfume, cologne and air fresheners. In addition, it can also be used as an intermediate in the synthesis of various chemicals and drugs.

HY-W027544S1

(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6

(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d₆ is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3]. (7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-156302

Coumarin-PEG2-endoBCN		Labeling and Fluorescence Imaging BCN
Coumarin-PEG2-endoBCN is a fluorescent dye containing a coumarin fluorophore and can be used as a click chemistry reagent .

HY-156304

Coumarin-C2-TCO		TCO Labeling and Fluorescence Imaging
Coumarin-C2-TCO is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.

HY-156303

Coumarin-PEG2-TCO		TCO Labeling and Fluorescence Imaging
Coumarin-PEG2-TCO is a dye derivative of Coumarin (HY-N0709) containing 2 PEG units. Coumarin-PEG2-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.

HY-156306

Coumarin-PEG3-TCO		Labeling and Fluorescence Imaging TCO
Coumarin-PEG3-TCO is a dye derivative of Coumarin (HY-N0709) containing 3 PEG units. Coumarin-PEG3-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.

HY-156309

Coumarin-PEG8-tetrazine		Labeling and Fluorescence Imaging Tetrazine
Coumarin-PEG8-tetrazine is a dye derivative of Coumarin (HY-N0709) containing 8 PEG units. Coumarin-PEG8-tetrazine contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-156305

Coumarin-C2-exo-BCN		BCN Labeling and Fluorescence Imaging
Coumarin-C2-exoBCN is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-exoBCN contains the lyophilic bidentate macrocyclic ligand exo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, exo-BCN can react with molecules containing azide groups to generate stable triazoles under catalyst-free conditions.

HY-W027544S1

(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 5-(Dimethyl-d6-amino)-N-(prop-2-ynyl)naphthalene-1-sulfonamide		Alkynes
(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d₆ is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3]. (7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Coumarins

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Natural
Products