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S-Sulfo-DL-cysteine-2,3,3-d<sub>3</sub>-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (19) Amino Acid Derivatives (8) Bacterial (1) Beta-lactamase (1) Biochemical Assay Reagents (5) Cathepsin (2) Cholinesterase (ChE) (1) Drug-Linker Conjugates for ADC (3) Endogenous Metabolite (11) Fluorescent Dye (27) Glyoxalase (GLO) (1) Isotope-Labeled Compounds (6) Oxytocin Receptor (1) PROTAC Linkers (8) Reactive Oxygen Species (2) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (35) Cardiovascular Disease (2) Infection (2) Inflammation/Immunology (2) Metabolic Disease (11) Neurological Disease (4)
Click Chemistry:	ADC Synthesis (3) Labeling and Fluorescence Imaging (5) TCO (1) DBCO (6) PROTAC Synthesis (1) Azide (2) Tetrazine (5)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: ASCT P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-131516

*Tiopronin-cysteine* disulfide**	Others	Others
Tiopronin-cysteine disulfide is a disulfide formed by Tiopronin (HY-B0373) and cysteine .

HY-134495

*N-Acetyl-L-cysteine* ethyl ester** 5 Publications Verification N-Acetylcysteine ethyl ester; NACET	Reactive Oxygen Species	Metabolic Disease
N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC). N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H₂S) and can be used as an H₂S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant .

HY-121765

Dacisteine N,S-Diacetyl-L-cysteine	Endogenous Metabolite	Metabolic Disease
Dacisteine (N,S-Diacetyl-L-cysteine) is a cysteine derivative and displays a less New Delhi metallo-beta-lactamase-1 (NDM-1) inhibitor with an IC₅₀ value of 1000 μM . Dacisteine can be used for the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation .

HY-136158A

*6-Maleimidocaproic acid sulfo-NHS sodium* Sulfo-EMCS	PROTAC Linkers	Cancer
6-Maleimidocaproic acid sulfo-NHS (Sulfo-EMCS) sodium is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-151789

Sulfo DBCO-TFP Ester	ADC Linker	Others
Sulfo DBCO-TFP Ester is a water-soluble, sulfo-containing click chemistry reagent. Sulfo DBCO-TFP Ester enables simple and efficient incorporation of sulfo-DBCO moieties onto amine-containing molecules .

HY-146656S

*S-Sulfo-DL-cysteine-2,3,3-d3*	Glyoxalase (GLO) Isotope-Labeled Compounds	Others
S-Sulfo-DL-cysteine-2,3,3-d₃ is the deuterium labeled S-Sulfo-DL-cysteine-2,3,3.

HY-151215S

*S-Sulfo-DL-cysteine-2,3,3-d3-1*	Isotope-Labeled Compounds	Others
S-Sulfo-DL-cysteine-2,3,3-d₃-1 is the deuterium labeled S-Sulfo-DL-cysteine[1].

HY-137251

Sulfo-MBS sodium	Biochemical Assay Reagents	Others
Sulfo-MBS sodium is a heterobifunctional crosslinker with a maleimide group and an N-hydroxysuccinimide (NHS) ester group, which can react with cysteine residues and lysine residues on proteins. Sulfo-MBS sodium be used for protein cross-linking studies .

HY-P10533

Cysteine peptide	Biochemical Assay Reagents	Others
Cysteine peptide is a heptapeptide containing a cysteine residue whose thiol group makes it susceptible to a range of oxidative modifications. Cysteine peptide is used to detect the skin sensitization potential of chemicals including cosmetic ingredients .

HY-157203

*Cholic acid-cysteine-cyanuric chloride complex*	Others	Others
Cholic acid-cysteine-cyanuric chloride complex is a hapten linker molecule comprising of the antigen, cholic acid and the reactive group for covalent attachment, cyanuric chloride .

HY-140341A

Sulfo-NHS-Acetate sodium	PROTAC Linkers	Others
Sulfo-NHS-Acetate sodium is an alkyl chain-based PROTAC linker. Sulfo-NHS-Acetate sodium can be used in the synthesis of PROTACs .

HY-W123009

Sulfo-KMUS sodium salt 11-Maleimidoundecanoic acid Sulfo-N-succinimidyl ester sodium salt	Biochemical Assay Reagents	Others
Sulfo-KMUS (sodium salt) acts as a crosslinker .

HY-129525

Sulfo-SIAB	ADC Linker	Cancer
Sulfo-SIAB is a nonclaevable monovalent bilinker.

HY-129525A

Sulfo-SIAB sodium	ADC Linker	Cancer
Sulfo-SIAB sodium is a nonclaevable monovalent bilinker.

HY-W123028

Sulfo-SANPAH sodium	Biochemical Assay Reagents
Sulfo-SANPAH (sodium) is a biochemical reagent .

HY-W002074

*D-Cysteine* hydrochloride**	Amino Acid Derivatives	Others
D-Cysteine hydrochloride is a cysteine derivative .

HY-W055811

*D-Cysteine* hydrochloride hydrate**	Amino Acid Derivatives	Others
D-Cysteine hydrochloride hydrate is a cysteine derivative .

HY-128954

Sulfo-PDBA-DM4	Drug-Linker Conjugates for ADC	Inflammation/Immunology Cancer
Sulfo-PDBA-DM4 is a agent-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Sulfo-PDBA to make antibody agent conjugate (ADC). Sulfo-PDBA is a gluthatione cleavable linker.

HY-107783

Sulfo-GMBS	Others	Cancer
Sulfo-GMBS is a cross-linker. Among the amine-sulfhydryl cross-linkers, Sulfo-GMBS generated the largest number of cross-links and covered most of the cross-links that were identified with AMAS and GMBS .

HY-D1566

Sulfo-Cy7.5 maleimide	Fluorescent Dye	Others
Sulfo-Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .

HY-Y0337

L-Cysteine 4 Publications Verification cysteine	Endogenous Metabolite	Metabolic Disease Cancer
L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans .

HY-117080

Sulfo-EGS	Biochemical Assay Reagents	Others
Sulfo-EGS is a homobifunctional, amine-reactive chemical crosslinker. Sulfo-EGS is used to study protein-protein or protein-peptide interactions, which can determine the spatial proximity of amino acid residues in a protein complex, without relying on standards .

HY-129377

Sulfo-SPP	ADC Linker	Cancer
Sulfo-SPP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.

HY-129377A

Sulfo-SPP sodium	ADC Linker	Cancer
Sulfo-SPP sodium a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.

HY-D2241

Sulfo-Cy7-DBCO	Fluorescent Dye	Others
Sulfo-Cy7-DBCO is the water-soluble version of cyanine 7. Sulfo-Cy7-DBCO spectral properties are similar to Cy7. Sulfo-Cy7-DBCO is a near-infrared fluorescent dye .

HY-137383

Sulfo-SANPAH	Others	Cardiovascular Disease
Sulfo-SANPAH is a primary amine-nitrobenzene azide cross-linker .

HY-160255

N-Cbz-L-Cysteine Cbz-cysteine	Beta-lactamase	Infection
N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) is a potent β-lactamase II inhibitor with a K_i value of 97 µM .

HY-17541

Cysteine Protease inhibitor 3 Publications Verification	Cathepsin	Others
Cysteine Protease inhibitor is an inhibitor of cysteine protease.

HY-17541A

Cysteine Protease inhibitor hydrochloride 3 Publications Verification	Cathepsin	Others
Cysteine Protease inhibitor hydrochloride is an inhibitor of cysteine protease.

HY-101141

sulfo-SPDB-DM4	Drug-Linker Conjugates for ADC	Cancer
sulfo-SPDB-DM4 is a agent-linker conjugate for ADC by using the maytansinebased payload (DM4, an antitubulin agent) via the sulfo-SPDB linker.

HY-D1375A

Sulfo-Cy5 amine hydrochloride	Fluorescent Dye	Others
Sulfo-Cy5 amine hydrochloride is a near-infrared (NIR) amino fluorescent dye. Sulfo-Cy5 amine hydrochloride reacts with electrophilic substances .

HY-D1352

Sulfo-Cyanine7 NHS ester potassium	Fluorescent Dye	Others
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.

HY-129376

Sulfo-SNPB	ADC Linker	Cancer
Sulfo-SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).

HY-153631

Sulfo-TAG NHS ester disodium	Others	Inflammation/Immunology
Sulfo-TAG NHS ester (disodium) is an N-hydroxysuccinimide ester that can be coupled to proteins via primary amine groups. Sulfo-TAG NHS ester (disodium) can be used for antibody labeling .

HY-D1598

Sulfo-CY3 tetrazine potassium	Fluorescent Dye	Others
Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates . Sulfo-CY3 tetrazine (potassium) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-P4895

(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin	Oxytocin Receptor	Neurological Disease
(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin (OVT) is an oxytocin receptor antagonist. (d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin can be used for the research of neurological disease .

HY-129373

SPDMV-sulfo	ADC Linker	Cancer
SPDMV-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).

HY-W018555

D-Cysteine	Endogenous Metabolite Bacterial	Infection Neurological Disease
D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of *Escherichia coli* growth. D-cysteine is mediated by D-amino acid oxidase to produce H₂S and is a neuroprotectant against cerebellar ataxias. D-Cysteine could inhibit the growth and cariogenic virulence of dual-species biofilms formed by *S. mutans* and *S. sanguinis* .

HY-136291

Sulfo-SPDB-DGN462	Drug-Linker Conjugates for ADC	Cancer
Sulfo-SPDB-DGN462 is a agent-linker conjugate for ADC. Sulfo-SPDB-DGN462 consists a toxin DGN462 (HY-101150) conjugated to the cleavable Sulfo-SPDB linker. DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML).

HY-151712

Sulfo-Cy5-Methyltetrazine	Fluorescent Dye	Others
Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.

HY-129370

SPDB-sulfo	ADC Linker	Cancer
SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) .

HY-140341

Sulfo-NHS-Acetate	PROTAC Linkers	Cancer
Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-101151

sulfo-SPDB	ADC Linker	Cancer
sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-133543

SPDP-sulfo	ADC Linker	Cancer
SPDP-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-D2132

Sulfo-Cy5.5-ALN	Fluorescent Dye	Cancer
Sulfo-Cy5.5-ALN is a fluorescent labeled alendronate, which targets bone. Sulfo-Cy5.5-ALN binds to hydroxyapatite and differentiated osteoblasts in vitro. Sulfo-Cy5.5-ALN selectively binds to the mineralized areas of the tumor. Sulfo-Cy5.5-ALN can be used to detect bone overgrowth in prostate bone metastasis .

HY-151713

Sulfo-Cy3-Methyltetrazine	Fluorescent Dye	Others
Sulfo-Cy3-Methyltetrazine (figure 7 compound 5) is a click chemistry reagent containing methyltetrazine and a water-soluble dye. Sulfo-Cy3-Methyltetrazine shows good stability at physiological pH. Sulfo-Cy3-Methyltetrazine can be coupled to trans-cyclooctene and is also highly reactive towards cyclooctene .

HY-111496

Sulfo-NHS-SS-Biotin sodium 1 Publications Verification	Fluorescent Dye	Others
Sulfo-NHS-SS-biotin is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin can be used for the labeling and purifying of cell-surface protein .

HY-D2223

Sulfo-Cy5 dUTP	Fluorescent Dye	Others
Sulfo-Cy5 dUTP is a modified nucleoside triphosphate used for DNase labeling. Sulfo-Cy5 dUTP is a bright far-red emitting dye for the Cy5 channel .

HY-126495

Sulfo-LC-SPDP	ADC Linker	Cancer
Sulfo-LC-SPDP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.

HY-126503

*trans-Sulfo-SMCC*	ADC Linker	Cancer
trans-Sulfo-SMCC is a non-cleavable and membrane permeable ADC crosslinker.

Cat. No.	Product Name

HY-L153

Cysteine Targeted Covalent Library

4,845 compounds

Covalent inhibitors are small molecules that can bind specifically to target proteins through covalent bonds and inhibit their biological functions. Although for a long time, covalent targeting has been playing a subordinate role in drug discovery, with an increasing number of reports on successful clinical applications of such drugs, the potential of these agents is now being acknowledged. Currently, cysteine is the most common covalent amino acid residue in a variety of covalent drugs, and various warheads have been developed that can react with cysteine, providing the key building blocks for covalent drugs to form covalent bonds.

To meet the development needs of covalent inhibitors targeting cysteine, MCE has designed a unique collection of 4,845 compounds with different covalent warheads that target cysteine. The MCE Cysteine Targeted Covalent Library is designed using the following covalent warheads: Acrylamides, Propiolic acid ester, Dimethylamine functionalized acrylamides, Chloroacetamides, Acrylonitrile, 2-Cyanoacrylamide, Aziridine, Haloacetamide, etc.

HY-L154

Cysteine Targeted Covalent Fragment Library

3,389 compounds

To meet the development needs of covalent inhibitors targeting cysteine, MCE has designed a unique collection of 3,389 fragments with different covalent warheads that target cysteine. The MCE Cysteine Targeted Covalent Fragment Library is designed using the following covalent warheads: Acrylamides, Propiolic acid ester, Dimethylamine functionalized acrylamides, Chloroacetamides, Acrylonitrile, 2-Cyanoacrylamide, Aziridine, Haloacetamide, etc. All fragments are pre-filtered with the Rule of Three restrictions which can be used for fragment-based covalent drug development.

HY-L915

Lysine Focused Covalent Fragment Library

445 compounds

Lysine is the second most common target residue used in the design of TCIs and related covalent ligands. Its appeal lies in its abundance in human proteins, which is approximately three times higher than that of cysteine (5.8% vs. 1.9%). This significantly increases the number of proteins suitable for covalent targeting, especially given that many human proteins lack ligandable cysteine residues. Moreover, it has been suggested that functional lysines have a lower probability of being replaced by mutation, as they often play a crucial role in catalysis by acting as bases or nucleophiles. Additionally, lysines are essential for maintaining the structural integrity of proteins and for regulating post-translational modifications (PTMs). Consequently, targeting lysine has garnered significant interest in recent years.

Through careful selection, we constructed a structural filter containing over 110 electrophilic groups. By analyzing the electrophilic fragments selected by the structural filter, we removed any molecules with trivial or undesirable structural features. Ultimately, we obtained 445 fragment molecules which can target lysine residue and can be used for fragment-based covalent drug discovery.

HY-L175

Inflammasomes related Compound Library

82 compounds

Inflammasomes are classic pattern recognition receptors for natural immune responses. Inflammasomes are polymeric protein complexes that regulate inflammatory responses and pyrolytic cell death, thereby exerting the host's defense against microorganisms. Inflammasomes sensors are associated with adapter proteins, activating inflammatory caspase-1, releasing inflammatory cytokines and inducing cell death, endowing the host with defense against pathogens. NLRP1, NLRP3, NLRC4, AIM2, and pyrin are considered typical inflammasomes because they convert cysteine asparaginase-1 into catalytically active capsaicin-1. In addition to infectious diseases, the importance of inflammasomes is also related to various clinical diseases, such as autoimmune diseases, neurodegeneration and metabolic disorders, and the development of cancer. Therefore, it is necessary to strictly regulate the activation and function of inflammasomes to avoid accidental host tissue damage while inducing pathogens to kill the inflammatory response.

MCE designs a unique collection of 82 inflammasomes related compounds. It is a good tool to be used for research on Inflammation, cancer and other diseases.

HY-L081

Phosphatase Inhibitor Library

117 compounds

Protein phosphorylation is a key post-translational modification underlying the regulation of many cellular processes. Phosphatases and kinases contribute to the regulation of protein phosphorylation homeostasis in the cell. This reversible regulation of protein phosphorylation is critical for the proper control of a wide range of cellular activities, including cell cycle, proliferation and differentiation, metabolism, cell-cell interactions, etc.

Protein phosphatases have evolved in separate families that are structurally and mechanistically distinct. Based on substrate specificity and functional diversity, protein phosphatases are classified into two superfamilies: Protein serine/threonine phosphatases and Protein tyrosine phosphatases. Ser/Thr phosphatases are metalloenzymes belonging to two major gene families termed PPP (phosphoprotein phosphatase) and PPM (metal-dependent protein phosphatases), whereas protein tyrosine phosphatases (PTPs) belong to distinct classes of enzymes that utilize a phospho-cysteine enzyme intermediate as a part of their catalytic action.

MCE supplies a unique collection of 117 phosphatase inhibitors that mainly targeting protein tyrosine phosphatases (PTPs) and serine/threonine-specific protein phosphatases. MCE Phosphatase Inhibitor Library is a useful tool for phosphatase drug discovery and related research.

HY-L908

Lead-like Covalent Screening Library

1,049 compounds

Small molecule covalent inhibitors, or irreversible inhibitors, are a type of inhibitors that exert their biological functions by irreversibly binding to target through covalent bonds. Compared with non-covalent inhibitors, covalent inhibitors have obvious advantages in bioactivity, such that covalent warheads can target rare residues of a particular target protein, thus leading to the development of highly selective inhibitors and achieving a more complete and continued target occupancy in living systems. In recent years, the distinct strengths of covalent inhibitors in overcoming drug resistance had been recognized. However, toxicity can be a real challenge related to this class of therapeutics due to their potential for off-target reactivity and has led to these drugs being disfavored as a drug class. The drug design and optimization of covalent inhibitors has become a hot spot in drug discovery.

MCE Lead-like Covalent Screening Library offers a valuable resource of 1,049 lead-like compounds with commonly used covalent warheads. These warheads, such as acrylamide, activated terminal alkyne, acyloxymethyl ketone, and boronic acid, are capable of reacting with specific amino acid residues, including cysteine, lysine, serine, and histidine. The inclusion of these reactive warheads in the library allows researchers to explore the potential of covalent inhibition, a powerful approach in drug discovery.

HY-L913

Tyrosine Focused Covalent Fragment Library

124 compounds

Recently, significant advancements in tyrosine-targeting electrophiles have primarily occurred in the field of protein-protein interactions (PPIs), where cysteine residues are often underrepresented and novel chemistries are needed to address these interfaces. In this context, tyrosines are frequently more accessible compared to more buried binding sites. Moreover, they are commonly found at "hot spots," which are functional epitopes of PPIs, with 12.3% of the residues consisting of tyrosines. This prevalence is likely due to the hydrophobic nature of tyrosine, its ability to participate in aromatic π-interactions, and its capacity for hydrogen bonding. Beyond PPIs, some progress has also been made in covalent tyrosine targeting in other areas where more commonly addressed side chains are lacking. Even though tyrosine has a slightly lower pKa value compared to the protonated lysine side chain (approximately 10 vs. 10.5 for the unprotected amino acid side chains), significantly less progress has been made in the development of tyrosine-targeted covalent ligands compared to lysine. This is likely due to the reduced flexibility of the tyrosine side chain and the greater steric hindrance of its hydroxy group, which makes it more challenging to adopt suitable reaction geometries.

Through careful selection, we constructed a structural filter containing over 110 electrophilic groups. By analyzing the electrophilic fragments selected by the structural filter, we removed any molecules with trivial or undesirable structural features. Ultimately, we obtained 124 fragment molecules which can target tyrosine residue and can be used for fragment-based covalent drug discovery.

Cat. No.	Product Name	Type

HY-D1566

Sulfo-Cy7.5 maleimide

Fluorescent Dyes/Probes

Sulfo-Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .

HY-111496

Sulfo-NHS-SS-Biotin sodium 1 Publications Verification	Dyes
Sulfo-NHS-SS-biotin is a long-chain cleavable and cell-impermeant amine-reactive biotinylation reagent. Sulfo-NHS-SS-biotin can be used for the labeling and purifying of cell-surface protein .

HY-D2241

Sulfo-Cy7-DBCO	Fluorescent Dyes/Probes
Sulfo-Cy7-DBCO is the water-soluble version of cyanine 7. Sulfo-Cy7-DBCO spectral properties are similar to Cy7. Sulfo-Cy7-DBCO is a near-infrared fluorescent dye .

HY-D1375A

Sulfo-Cy5 amine hydrochloride	Fluorescent Dyes/Probes
Sulfo-Cy5 amine hydrochloride is a near-infrared (NIR) amino fluorescent dye. Sulfo-Cy5 amine hydrochloride reacts with electrophilic substances .

HY-D1352

Sulfo-Cyanine7 NHS ester potassium	Fluorescent Dyes/Probes
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.

HY-D1598

Sulfo-CY3 tetrazine potassium

Fluorescent Dyes/Probes

Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates . Sulfo-CY3 tetrazine (potassium) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-151712

Sulfo-Cy5-Methyltetrazine	Fluorescent Dyes/Probes
Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.

HY-D2132

Sulfo-Cy5.5-ALN	Fluorescent Dyes/Probes
Sulfo-Cy5.5-ALN is a fluorescent labeled alendronate, which targets bone. Sulfo-Cy5.5-ALN binds to hydroxyapatite and differentiated osteoblasts in vitro. Sulfo-Cy5.5-ALN selectively binds to the mineralized areas of the tumor. Sulfo-Cy5.5-ALN can be used to detect bone overgrowth in prostate bone metastasis .

HY-151713

Sulfo-Cy3-Methyltetrazine	Fluorescent Dyes/Probes
Sulfo-Cy3-Methyltetrazine (figure 7 compound 5) is a click chemistry reagent containing methyltetrazine and a water-soluble dye. Sulfo-Cy3-Methyltetrazine shows good stability at physiological pH. Sulfo-Cy3-Methyltetrazine can be coupled to trans-cyclooctene and is also highly reactive towards cyclooctene .

HY-D2223

Sulfo-Cy5 dUTP	Fluorescent Dyes/Probes
Sulfo-Cy5 dUTP is a modified nucleoside triphosphate used for DNase labeling. Sulfo-Cy5 dUTP is a bright far-red emitting dye for the Cy5 channel .

HY-D1541

Sulfo-Cyanine5.5 alkyne	Fluorescent Dyes/Probes
Sulfo-Cyanine5.5 alkyne, a near-infrared (NIR) fluorescent dye, is an alkyne modified Sulfo-Cyanine5.5 (Ex=67 8nm, Em=694 nm). Sulfo-Cyanine5.5 alkyne can react with azides for Click Chemistry labeling.

HY-137098

Sulfo-Cy3 maleimide potassium	Fluorescent Dyes/Probes
Sulfo-Cy3 maleimide potassium is a fluorescent dye with a maleimide functionality at the end a short alkyl linker. Sulfo-Cy3 maleimide potassium can be used for the labeling of antibodies and other labile proteins .

HY-D1600

Sulfo-Cyanine5.5 maleimide potassium	Dyes
Sulfo-Cyanine5.5 maleimide potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .

HY-D1352A

Sulfo-Cyanine7 NHS ester TEA	Fluorescent Dyes/Probes
Sulfo-Cyanine7 NHS ester (TEA) is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester (TEA) reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.

HY-123687

*DBCO-Sulfo-NHS ester sodium*	Dyes
DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-D1272

Sulfo-Cy3 amine

Sulfo-Cyanine3 amine

Fluorescent Dyes/Probes

Sulfo-Cy3 amine is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.

HY-D1390A

Sulfo-Cy5-Mal	Fluorescent Dyes/Probes
Sulfo-Cy5-Mal is a fluorescent dye with the form of active ester that reacts with thiol groups in proteins to form stable conjugates. Sulfo-Cy5-Mal that can be used to label protein .

HY-D2219

Sulfo-Cy7 tetrazine	Fluorescent Dyes/Probes
Sulfo-Cy7 tetrazine is a near-infrared water-soluble fluorophore. Sulfo-Cy7 tetrazine contains the methyltetrazine group for rapid, efficient, and metal-free conjugation to cycloolefin in a reaction called TCO linkage .

HY-151759

Sulfo-Cy5-TCO	Dyes
Sulfo-Cy5-TCO is a click chemistry reagent containing a TCO group. Sulfo-Cy5-TCO is water soluble dye, which is highly reactive with tetrazines and methyltetrazines with the fastest bioconjugation speed .

HY-D1366

Sulfo-Cyanine5.5 carboxylic acid	Fluorescent Dyes/Probes
Sulfo-Cyanine5.5 carboxylic acidCI Pigment violet 32 is a water-soluble, far-red emitting fluorophore. Due to its four sulfo groups, this dye has a negative charge at neutral pH and is very hydrophilic. As a cyanine dye, sulfo-Cyanine5.5 shows a very low dependence of fluorescence on pH and a very high extinction coefficient.

HY-D1365

Sulfo-Cy3(Me)COOH	Fluorescent Dyes/Probes
Sulfo-Cy3(Me)COOH is a sulfo-Cyanine3 derivative. Cyanine3 is an orange-fluorescent label dye for protein and nucleic acid (Ex=554 nm, Em=568 nm) .

HY-D1568

Sulfo-Cy7.5 NHS ester	Dyes
Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .

HY-D1848

Sulfo-Cy3-NHS disodium	Fluorescent Dyes/Probes
Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.

HY-D1374

Sulfo-Cy5 carboxylic acid potassium	Fluorescent Dyes/Probes
Sulfo-Cy5 carboxylic acid potassium is a water-soluble, inactive Cy5 carboxylic acid.

HY-D1096

Sulfo-Cy5 diacid potassium	Dyes
Sulfo-Cy5 diacid potassium is a water-soluble, inactive Cy5 carboxylic acid.

HY-D1881

Sulfo-Cy7 carboxylic acid	Fluorescent Dyes/Probes
Sulfo-Cy7 carboxylic acid (compound 6m) is a cyanine dye .

HY-145746

Sulfo-Cy5 azide

Fluorescent Dyes/Probes

Sulfo-Cy5 azide is a fluorescent dye and nontargeted contrast agent. Sulfo-Cy5 azide has been used to label and image RNA . Sulfo-Cy5 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-D1389

Sulfo-CY-5.5 NHS ester tripotassium Sulfo-Cyanine5.5 NHS ester tripotassium	Fluorescent Dyes/Probes
Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-121765

Dacisteine N,S-Diacetyl-L-cysteine	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Dacisteine (N,S-Diacetyl-L-cysteine) is a cysteine derivative and displays a less New Delhi metallo-beta-lactamase-1 (NDM-1) inhibitor with an IC₅₀ value of 1000 μM . Dacisteine can be used for the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation .

HY-Y0337

L-Cysteine 4 Publications Verification cysteine	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans .

HY-W018555

D-Cysteine	Structural Classification Human Gut Microbiota Metabolites Microorganisms Source classification Amino acids Endogenous metabolite	Endogenous Metabolite Bacterial
D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of *Escherichia coli* growth. D-cysteine is mediated by D-amino acid oxidase to produce H₂S and is a neuroprotectant against cerebellar ataxias. D-Cysteine could inhibit the growth and cariogenic virulence of dual-species biofilms formed by *S. mutans* and *S. sanguinis* .

HY-Y0337A

*L-Cysteine* hydrochloride** 4 Publications Verification	Structural Classification Classification of Application Fields Anti-aging Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) .

HY-W016715

*L-Cysteine* hydrochloride hydrate** 4 Publications Verification	Structural Classification Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Cysteine hydrochloride hydrate is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride hydrate suppresses ghrelin and reduces appetite in rodents and humans .

HY-W016715R

*L-Cysteine* hydrochloride hydrate (Standard)**	Structural Classification Source classification Amino acids Endogenous metabolite	Endogenous Metabolite
L-Cysteine (hydrochloride hydrate) (Standard) is the analytical standard of L-Cysteine (hydrochloride hydrate). This product is intended for research and analytical applications. L-Cysteine hydrochloride hydrate is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride hydrate suppresses ghrelin and reduces appetite in rodents and humans .

HY-Y0337R

*L-Cysteine* (Standard)**	Structural Classification Human Gut Microbiota Metabolites Microorganisms Source classification Amino acids Endogenous metabolite	Endogenous Metabolite
L-Cysteine (Standard) is the analytical standard of L-Cysteine. This product is intended for research and analytical applications. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans .

HY-Y0337AR

*L-Cysteine* hydrochloride (Standard)**	Structural Classification Source classification Amino acids Endogenous metabolite	Endogenous Metabolite
L-Cysteine (hydrochloride) (Standard) is the analytical standard of L-Cysteine (hydrochloride). This product is intended for research and analytical applications. L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) [4].

Species:	Human (41) Mouse (13) Rat (1) Bovine (2) E.coli (2) Staphylococcus aureus (1) Pig (1)
Tag:	GFP (3) His (49) SUMO (3) Tag Free (5) Strep (6) Myc (1) GST (2) Trx (1) Fc (5) Flag (7)
Source:	HEK293 (32) Sf9 insect cells (4) E. coli (25)

Cat. No.	Compare	Product Name	Species	Source

HY-P70897A

	Legumain Protein, Human (HEK293, C-His) Legumain; Asparaginyl Endopeptidase; Protease cysteine 1; LGMN; PRSC1	Human	HEK293
	Legumain proteins can slowly cleave aspartyl bonds, especially under acidic conditions.Legumain Protein, Human (HEK293, C-His) is the recombinant human-derived Legumain protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P77438

	Legumain Protein, Pig (416a.a, HEK293, His) Legumain; Asparaginyl Endopeptidase; Protease cysteine 1; LGMN; PRSC1	Pig	HEK293
	Legumain proteins can slowly cleave aspartyl bonds, especially under acidic conditions. Legumain Protein, Pig (416a.a, HEK293, His) is the recombinant pig-derived Legumain protein, expressed by HEK293 , with N-His labeled tag. The total length of Legumain Protein, Pig (416a.a, HEK293, His) is 416 a.a., with molecular weight of ~52.5 kDa.

HY-P70066

	*CDO1/Cysteine* dioxygenase type 1 Protein, Human (His)** 1 Publications Verification rHucysteine dioxygenase type 1/CDO1, His; cysteine Dioxygenase Type 1; cysteine Dioxygenase Type I; CDO; CDO-I; CDO1	Human	E. coli
	Cysteine dioxygenase (CDO1) plays a crucial role in cellular metabolism by catalyzing the oxidation of cysteine to cysteine sulfenic acid, a key step involving the addition of molecular dioxygen . This enzymatic process underlies cysteine catabolism and helps regulate sulfur amino acid metabolism. CDO1/Cysteine dioxygenase type 1 Protein, Human (His) is the recombinant human-derived CDO1/Cysteine dioxygenase type 1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of CDO1/Cysteine dioxygenase type 1 Protein, Human (His) is 200 a.a., with molecular weight of 20-28 kDa.

HY-P70216A

	Legumain Protein, Mouse (HEK293, C-His) rMuLegumain/Asparaginyl Endopeptidase, His; Legumain; Lgmn; Asparaginyl endopeptidase; Protease cysteine 1; Prsc1	Mouse	HEK293
	Legumain proteins can slowly cleave aspartyl bonds, especially under acidic conditions.Legumain Protein, Mouse (HEK293, C-His) is the recombinant mouse-derived Legumain protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P701199

	CSRP3 Protein, Human (HEK293, His) cysteine and glycine-rich protein 3; CSRP3; cysteine and glycine-rich protein 3	Human	HEK293

HY-P70306

	MGMT Protein, Human (His) rHuMethylated-DNA--protein-cysteine methyltransferase/MGMT, His; Methylated-DNA--protein-cysteine methyltransferase; 6-O-methylguanine-DNAmethyltransferase; O-6-methylguanine-DNA-alkyltransferase; MGMT	Human	E. coli
	MGMT Protein crucially defends against O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA, using a suicide reaction to repair methylated nucleobases. It stoichiometrically transfers the methyl group to a cysteine residue, but this process irreversibly inactivates MGMT. The sacrificial nature of MGMT's function emphasizes its commitment to safeguarding cellular DNA integrity at the expense of its own activity. MGMT Protein, Human (His) is the recombinant human-derived MGMT protein, expressed by E. coli , with N-6*His labeled tag. The total length of MGMT Protein, Human (His) is 207 a.a., with molecular weight of ~27.0 kDa.

HY-P75331

	CRIPT Protein, Human (His) cysteine-rich PDZ-binding protein; CRIPT; HSPC139	Human	E. coli
	CRIPT, a pivotal member of the minor spliceosome, plays a crucial role in U12-type intron splicing, contributing to RNA splicing intricacies. Beyond its splicing function, CRIPT anchors DLG4 within excitatory synapses, interacts with RNF113A, SF3B1/SF3b155, SF3B2/SF3b145, and PHF5A/SF3b14b in the minor spliceosome complex, and strongly associates with the PDZ3 domain of DLG4 family members, highlighting its synaptic involvement. Additionally, CRIPT interacts with microtubules, indicating a role in cytoskeletal dynamics, showcasing its multifaceted contributions. CRIPT Protein, Human (His) is the recombinant human-derived CRIPT protein, expressed by E. coli, with N-His labeled tag. The total length of CRIPT Protein, Human (His) is 101 a.a., with molecular weight of ~14 kDa.

HY-P7619

	ATG4C Protein, Human (His) rHuATG4C, His; cysteine Protease ATG4C; AUT-Like 3 cysteine Endopeptidase; ATG4C; APG4C;	Human	E. coli
	ATG4C Protein, Human (His) is a recombinant human Autophagy Related 4 Homolog C (Atg4C) expressed in E. coli with a His tag. Atg4C, a member of a family of cysteine proteinases, is a autophagy-regulating protease.

HY-P71259

	Resistin Protein, Human (His) 1 Publications Verification Resistin; Adipose tissue-specific secretory factor; cysteine-rich secreted protein FIZZ3; C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; cysteine-rich secreted protein A12-alpha-like 2; FIZZ3; HXCP1; RSTN; RETN	Human	E. coli
	Resistin, a hormone linking obesity to diabetes, may hinder insulin's glucose uptake stimulation in adipose cells, contributing to metabolic dysregulation. Additionally, it promotes myeloid cell chemotaxis and forms homodimers through disulfide linkages, interacting with DEFA1. Resistin's involvement in diverse cellular processes suggests its pivotal role in the complex interplay of metabolism, inflammation, and insulin responsiveness. Resistin Protein, Human (His) is the recombinant human-derived Resistin protein, expressed by E. coli , with C-6*His labeled tag.

HY-P703851

	LGMN Protein, Human (HEK293, His) Legumain; Asparaginyl endopeptidase; AEP; Protease; cysteine 1; LGMN	Human	HEK293

HY-P7618

	ATG4A Protein, Human (His) rHuATG4A, His; cysteine Protease ATG4A; AUT-Like 2 cysteine Endopeptidase; ATG4A; APG4A; AUTL2	Human	E. coli
	ATG4A Protein, Human (His) is a recombinant human Autophagy Related 4 Homolog A (ATG4A) expressed in E. coli with a His tag. ATG4A, a member of a family of cysteine proteinases, is a autophagy-regulating protease.

HY-P71694

	MetC Protein, E.coli (His) metC; b3008; JW2975Cystathionine beta-lyase MetC; CBL; CL; CD; EC 4.4.1.28; cysteine lyase MetC; cysteine-S-conjugate beta-lyase MetC	E.coli	E. coli
	MetC protein is a multifunctional enzyme that catalyzes the cleavage of cystathionine to homocysteine, pyruvate, and ammonia, which is essential for methionine biosynthesis. It also acts as a cysteine desulfurase, converting cysteine into sulfide. MetC Protein, E.coli (His) is the recombinant E. coli-derived MetC protein, expressed by E. coli , with N-His labeled tag.

HY-P70926

	LMCD1 Protein, Human (His) LIM and cysteine-rich domains protein 1; LMCD1; Dyxin	Human	E. coli
	The LMCD1 protein is a transcriptional cofactor that regulates GATA6 by blocking its DNA binding, thereby inhibiting transcriptional activation in lung and heart tissues. It inhibits GATA6-mediated transactivation of tissue-specific promoters, which is critical for developmental processes. LMCD1 Protein, Human (His) is the recombinant human-derived LMCD1 protein, expressed by E. coli , with N-6His, C-6His labeled tag.

HY-P76290

	CRIP2 Protein, Human (sf9) cysteine-rich protein 2; CRP-2; Protein ESP1	Human	Sf9 insect cells
	The CRIP2 protein, also known as cysteine-rich intestinal protein 2, is a protein involved in a variety of cellular processes. CRIP2 protein interacts with TGFB1I1. CRIP2 Protein, Human (sf9) is the recombinant human-derived CRIP2 protein, expressed by Sf9 insect cells , with tag free. The total length of CRIP2 Protein, Human (sf9) is 208 a.a., with molecular weight of ~26 KDa.

HY-P71290

	SENP8 Protein, Human (His) Sentrin-Specific Protease 8; Deneddylase-1; NEDD8-Specific Protease 1; Protease cysteine 2; Sentrin/SUMO-Specific Protease SENP8; SENP8; DEN1; NEDP1; PRSC2	Human	E. coli
	SENP8 protein, a pivotal protease in the NEDD8 pathway, plays a dual role in catalyzing the processing of full-length NEDD8 into its mature form and facilitating the deconjugation of NEDD8 from specific target proteins, including cullins and p53. SENP8's dual functionality underscores its crucial role in regulating NEDD8 modification, impacting various cellular pathways and functions. SENP8 Protein, Human (His) is the recombinant human-derived SENP8 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SENP8 Protein, Human (His) is 212 a.a., with molecular weight of ~22.0 kDa.

HY-P73420

	SPARC Protein, Rat (HEK293, His) SPARC; BM-40; Osteonectin; ON; Secreted Protein Acidic and Rich in cysteine	Rat	HEK293
	SPARC protein is involved in the regulation of cell growth and may play a regulatory role by affecting the interaction of extracellular matrix and cytokines. SPRC protein can bind calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. It has two calcium binding sites: one is an acidic domain that can bind 5-8 Ca²⁺ with low affinity, and the other is an EF-hand loop that can bind Ca²⁺ ions with high affinity. SPARC Protein, Rat (HEK293, His) is the recombinant rat-derived SPARC protein, expressed by HEK293 , with C-His labeled tag. The total length of SPARC Protein, Rat (HEK293, His) is 284 a.a., with molecular weight of ~33.8-40 kDa.

HY-P75695

	CSRP1 Protein, Mouse (His) cysteine and glycine-rich protein 1; CRP; CRP1; Csrp1	Mouse	E. coli
	CSRP1 protein may contribute to neuronal development through its interactions with ASCC1, ASCC2, and TRIP4. These connections suggest a regulatory role for CSRP1 in molecular events involved in neuronal growth and differentiation. Understanding the dynamics of CSRP1 interactions with these proteins could enhance our knowledge of neuronal development and facilitate targeted interventions in neurological contexts. CSRP1 Protein, Mouse (His) is the recombinant mouse-derived CSRP1 protein, expressed by E. coli , with C-His labeled tag. The total length of CSRP1 Protein, Mouse (His) is 193 a.a., with molecular weight of ~23 kDa.

HY-P76288

	CRELD2 Protein, Mouse (HEK293, Fc) cysteine-Rich With EGF-Like Domain Protein 2; CRELD2	Mouse	HEK293
	CRELD2 Protein, potentially acting as a protein disulfide isomerase, may play a role in the unfolded protein response. It is also implicated in regulating the transport of the alpha4-beta2 neuronal acetylcholine receptor, showcasing its versatility in cellular processes related to protein folding and neuronal receptor dynamics. These functions suggest CRELD2's involvement in maintaining cellular homeostasis. CRELD2 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CRELD2 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76289

	CRELD2 Protein, Mouse (HEK293, His) cysteine-Rich With EGF-Like Domain Protein 2; CRELD2	Mouse	HEK293
	CRELD2 Protein, potentially acting as a protein disulfide isomerase, may play a role in the unfolded protein response. It is also implicated in regulating the transport of the alpha4-beta2 neuronal acetylcholine receptor, showcasing its versatility in cellular processes related to protein folding and neuronal receptor dynamics. These functions suggest CRELD2's involvement in maintaining cellular homeostasis. CRELD2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CRELD2 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76291

	CRIP2 Protein, Human (sf9, His-GST) cysteine-rich protein 2; CRP-2; Protein ESP1	Human	Sf9 insect cells
	The CRIP2 protein, also known as cysteine-rich intestinal protein 2, is a protein involved in a variety of cellular processes. CRIP2 protein interacts with TGFB1I1. CRIP2 Protein, Human (sf9, His-GST) is the recombinant human-derived CRIP2 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of CRIP2 Protein, Human (sf9, His-GST) is 208 a.a., with molecular weight of ~49 KDa.

HY-P76298

	CSRP1 Protein, Human (His) cysteine and glycine-rich protein 1; CRP1; HEL-141; CSRP; CYRP	Human	E. coli
	The CSRP1 protein is a protein that may be involved in neuronal development. It is known to interact with three other proteins: ASCC1, ASCC2 and TRIP4. CSRP1 Protein, Human (His) is the recombinant human-derived CSRP1 protein, expressed by E. coli , with C-His labeled tag. The total length of CSRP1 Protein, Human (His) is 193 a.a., with molecular weight of ~22 KDa.

HY-P71624

	Staphopain B Protein, S. aureus (GST) sspB; SAV1047; Staphopain B; EC 3.4.22.-; Staphylococcal cysteine proteinase B; Staphylopain B	Staphylococcus aureus	E. coli
	Staphopain B is a cysteine protease that severely disrupts host immunity by degrading elastin, fibrin, fibronectin, and kininogen. It blocks phagocytosis of opsonized Staphylococcus aureus and induces neutrophil and monocyte death through proteolytic activity. Staphopain B Protein, S. aureus (GST) is the recombinant Staphylococcus aureus-derived Staphopain B protein, expressed by E. coli , with N-GST labeled tag.

HY-P76061

	Serpin B6b Protein, Mouse (sf9, His) NK13; Serine (Or cysteine) peptidase inhibitor, clade B, member 6B	Mouse	Sf9 insect cells
	Serpin B6b protein is an important member of the serine protease inhibitor family and plays a crucial role as a serine protease inhibitor, regulating proteolytic activity.His research enhances the understanding of cellular processes related to proteolysis and its therapeutic applications.Serpin B6b Protein, Mouse (sf9, His) is the recombinant mouse-derived Serpin B6b protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P7753

	Cathepsin L1 Protein, Mouse (HEK293, His) rMuCathepsin L, His; Cathepsin L1; Major excreted protein; p39 cysteine proteinase; CTSL1	Mouse	HEK293
	Cathepsin L Protein, Mouse (HEK293, His) is a lysosomal acid cysteine protease, which is associated with tumor occurrence, development, and metastasis.

HY-P70025

	Cystathionine gamma-lyase/CTH Protein, Human rHuCystathionine gamma-lyase/CTH; Cystathionine Gamma-Lyase; cysteine-Protein Sulfhydrase; Gamma-Cystathionase; CTH	Human	E. coli
	CTH protein is a cysteine protein sulfatase that catalyzes the final step of the transsulfuration pathway in a PLP-dependent manner. Cystathionine gamma-lyase/CTH Protein, Human is the recombinant human-derived Cystathionine gamma-lyase/CTH protein, expressed by E. coli , with tag free. The total length of Cystathionine gamma-lyase/CTH Protein, Human is 405 a.a., with molecular weight of ~50.0 kDa.

HY-P73680

	Resistin Protein, Mouse (HEK293, Fc) Resistin; Adipose tissue-specific secretory factor; cysteine-rich secreted protein FIZZ3; FIZZ3; ADSF; RSTN; RETN	Mouse	HEK293
	Resistin hormone inhibits insulin's efficacy in promoting glucose uptake into adipose cells, potentially linking obesity and diabetes. Structurally, it forms stabilizing disulfide linkages as a homodimer. The interplay between resistin and insulin reveals complex molecular mechanisms in metabolic regulation, providing insights into how resistin may contribute to the pathophysiological connections between obesity and diabetes. Resistin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Resistin protein, expressed by HEK293 , with N-hFc labeled tag. The total length of Resistin Protein, Mouse (HEK293, Fc) is 94 a.a., with molecular weight of ~39 kDa.

HY-P76285

	CRELD1 Protein, Human (HEK293, His) Protein disulfide isomerase CRELD1; cysteine-rich with EGF-like domain protein 1; CIRRIN	Human	HEK293
	CRELD1 Protein, acting as a protein disulfide isomerase, aids in the correct folding and assembly of proteins, crucial for cellular homeostasis. It also contributes to the proper localization of acetylcholine receptors (AChRs) to the plasma membrane, emphasizing its significance in maintaining protein structure and membrane receptor distribution. CRELD1 Protein, Human (HEK293, His) is the recombinant human-derived CRELD1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76286

	CRELD1 Protein, Mouse (HEK293, Fc) Protein disulfide isomerase CRELD1; cysteine-rich with EGF-like domain protein 1; CIRRIN	Mouse	HEK293
	The CRELD1 protein is a member of the protein disulfide isomerase family and is actively involved in rearrangements of disulfide bonds that contribute to important cellular processes. Of particular note is the role of CRELD1 in promoting the localization of acetylcholine receptors (AChR) to the plasma membrane. CRELD1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CRELD1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P76287

	CRELD1 Protein, Mouse (HEK293, His) Protein disulfide isomerase CRELD1; cysteine-rich with EGF-like domain protein 1; CIRRIN	Mouse	HEK293
	The CRELD1 protein is a member of the protein disulfide isomerase family and is actively involved in rearrangements of disulfide bonds that contribute to important cellular processes. Of particular note is the role of CRELD1 in promoting the localization of acetylcholine receptors (AChR) to the plasma membrane. CRELD1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CRELD1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P71094

	SPARC Protein, Human (HEK293, His) 1 Publications Verification SPARC; Basement-Membrane Protein 40; BM-40; Osteonectin; ON; Secreted Protein Acidic and Rich in cysteine; SPARC; ON	Human	HEK293
	SPARC proteins are essential for lipid transport and are involved in the production, transformation, and clearance of plasma lipoproteins. It interacts with different particles, shows a preference for HDL, and binds to cellular receptors such as LDLR and VLDLR to promote the uptake of APOE-containing lipoproteins. SPARC Protein, Human (HEK293, His) is the recombinant human-derived SPARC protein, expressed by HEK293 , with C-6*His labeled tag. The total length of SPARC Protein, Human (HEK293, His) is 286 a.a., with molecular weight of ~38.0 kDa.

HY-P72151

	CSAD Protein, Mouse (His-SUMO) Csadcysteine sulfinic acid decarboxylase; EC 4.1.1.29; Aspartate 1-decarboxylase; EC 4.1.1.11; cysteine-sulfinate decarboxylase; Sulfinoalanine decarboxylase	Mouse	E. coli
	CSAD proteins play a crucial role in the metabolism of sulfur-containing amino acids, catalyzing L-aspartate, 3-sulfinyl-L-alanine (cysteine sulfenic acid) and L-cysteine The acid is decarboxylated to produce β-alanine, hypotaurine and taurine respectively. Among these substrates, 3-sulfinyl-L-alanine is the preferred substrate for CSAD. CSAD Protein, Mouse (His-SUMO) is the recombinant mouse-derived CSAD protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of CSAD Protein, Mouse (His-SUMO) is 493 a.a., with molecular weight of ~71.1 kDa.

HY-P70081

	CRELD2 Protein, Human (HEK293, His) rHuProtein disulfide isomerase CRELD2/CRELD2, His; cysteine-Rich With EGF-Like Domain Protein 2; CRELD2	Human	HEK293
	CRELD2 Protein, potentially acting as a protein disulfide isomerase, may play a role in the unfolded protein response. It is also implicated in regulating the transport of the alpha4-beta2 neuronal acetylcholine receptor, showcasing its versatility in cellular processes related to protein folding and neuronal receptor dynamics. These functions suggest CRELD2's involvement in maintaining cellular homeostasis. CRELD2 Protein, Human (HEK293, His) is the recombinant human-derived CRELD2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CRELD2 Protein, Human (HEK293, His) is 297 a.a., with molecular weight of ~41 kDa.

HY-P76292

	CRISP-1 Protein, Mouse (HEK293, Fc) cysteine-rich secretory protein 1; CRISP1; Sperm-coating glycoprotein 1; SCP 1; Aeg-1	Mouse	HEK293
	CRISP-1 protein plays a crucial role in promoting the functional maturation of spermatozoa during their transition from the testis to the ductus deferens. Its involvement underscores its significance in the complex regulatory network governing male reproductive physiology, emphasizing its potential impact on sperm functionality and fertility as these cells navigate through the reproductive tract. CRISP-1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CRISP-1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CRISP-1 Protein, Mouse (HEK293, Fc) is 244 a.a., with molecular weight of ~52.4 KDa.

HY-P76293

	CRISP-1 Protein, Mouse (HEK293, His) cysteine-rich secretory protein 1; CRISP1; Sperm-coating glycoprotein 1; SCP 1; Aeg-1	Mouse	HEK293
	CRISP-1 protein plays a crucial role in promoting the functional maturation of spermatozoa during their transition from the testis to the ductus deferens. Its involvement underscores its significance in the complex regulatory network governing male reproductive physiology, emphasizing its potential impact on sperm functionality and fertility as these cells navigate through the reproductive tract. CRISP-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CRISP-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CRISP-1 Protein, Mouse (HEK293, His) is 244 a.a., with molecular weight of ~26 KDa.

HY-P701341

	Caspase-3/CASP3 Protein, Human 2 Publications Verification CASP3; Caspase-3; CASP-3; Apopain; cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1	Human	E. coli
	Caspase-3/CASP3 protein is a thiol protease critical in apoptosis and is activated by initiating caspases (CASP8, CASP9 and/or CASP10). It catalyzes the cleavage of multiple proteins in sympathetic neurons, including PARP1, SREBP, caspase-6, -7 and -9, huntingtin, and RET. Caspase-3/CASP3 Protein, Human is the recombinant human-derived Caspase-3/CASP3 protein, expressed by E. coli , with tag free. The total length of Caspase-3/CASP3 Protein, Human is 248 a.a., .

HY-P74650

	*PC4/SUB1 Protein, Human (His)* Activated RNA polymerase II transcriptional coactivator p15; PC4; p14; sub1; RPO2TC1	Human	E. coli
	The PC4/SUB1 protein acts as a multifunctional coactivator that cooperates with TAF to promote functional interactions between upstream activators and the general transcription machinery. Its role extends to the potential stability of multiprotein transcription complexes. PC4/SUB1 Protein, Human (His) is the recombinant human-derived PC4/SUB1 protein, expressed by E. coli , with N-His labeled tag. The total length of PC4/SUB1 Protein, Human (His) is 127 a.a., with molecular weight of ~19 kDa.

HY-P700637

	CRELD2 Protein, Human (329a.a, HEK293, His) rHuProtein disulfide isomerase CRELD2/CRELD2, His; cysteine-Rich With EGF-Like Domain Protein 2; CRELD2	Human	HEK293
	CRELD2 Protein, potentially acting as a protein disulfide isomerase, may play a role in the unfolded protein response. It is also implicated in regulating the transport of the alpha4-beta2 neuronal acetylcholine receptor, showcasing its versatility in cellular processes related to protein folding and neuronal receptor dynamics. These functions suggest CRELD2's involvement in maintaining cellular homeostasis. CRELD2 Protein, Human (329a.a, HEK293, His) is the recombinant human-derived CRELD2 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P71448

	ITGBL1 Protein, Human (Myc, His) ITGBL1; OSCP; TIED; Integrin beta-like protein 1; Osteoblast-specific cysteine-rich protein; Ten integrin EGF-like repeat domain-containing protein	Human	E. coli
	Integrin beta-like protein 1 (ITGBL1) is a beta integrin-related protein that is a member of the EGF-like protein family, containing integrin-like cysteine-rich repeats and may has integrin binding activity. ITGBL1 might be involved in cell adhesion mediated by integrin; cell-matrix adhesion; and integrin-mediated signaling pathway. ITGBL1 Protein, Human (Myc, His) is the recombinant human-derived ITGBL1 protein, expressed by E. coli , with C-Myc, N-10*His labeled tag. The total length of ITGBL1 Protein, Human (Myc, His) is 471 a.a., with molecular weight of ~67 kDa.

HY-P71511

	Gamma-GCS Protein, E.coli (His-SUMO) gshA; gsh-I; b2688; JW2663Glutamate--cysteine ligase; EC 6.3.2.2; Gamma-ECS; GCS; Gamma-glutamylcysteine synthetase	E.coli	E. coli
	Gamma-GCS protein is a key enzyme in sulfur metabolism and initiates glutathione synthesis by catalyzing the incorporation of L-cysteine and L-glutamic acid. This important molecule critical for cellular antioxidant defense is synthesized through a critical 1/2 step facilitated by γ-GCS. Gamma-GCS Protein, E.coli (His-SUMO) is the recombinant E. coli-derived Gamma-GCS protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

HY-P701342

	Caspase-3/CASP3 Protein, Human (His, Strep) CASP3; Caspase-3; CASP-3; Apopain; cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1	Human	E. coli
	Caspase-3/CASP3 protein is a thiol protease critical in apoptosis and is activated by initiating caspases (CASP8, CASP9 and/or CASP10). It catalyzes the cleavage of multiple proteins in sympathetic neurons, including PARP1, SREBP, caspase-6, -7 and -9, huntingtin, and RET. Caspase-3/CASP3 Protein, Human (His, Strep) is the recombinant human-derived Caspase-3/CASP3 protein, expressed by E. coli , with C-Strep, C-8*His labeled tag.

HY-P7822

	Cerberus 1/CER1 Protein, Human (HEK293, His) rHuCerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)/CER1, His; Cerberus; Cerberus-Related Protein; DAN Domain Family Member 4; CER1; DAND4	Human	HEK293
	The CER1 protein, a DAN family BMP antagonist, coordinates growth-promoting ureteric bud signaling by inducing BMP inhibition. CER1 also regulates embryogenesis and carcinogenesis by inhibiting NODAL signaling to SMAD2 or SMAD3 through ALK4/ALK7. Cerberus 1/CER1 Protein, Human (HEK293, His) is the recombinant human-derived Cerberus 1/CER1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Cerberus 1/CER1 Protein, Human (HEK293, His) is 250 a.a., with molecular weight of 35-42 kDa.

HY-P70042

	CRISP-3 Protein, Human (HEK293, His) rHucysteine-rich secretory protein 3/CRISP-3, His; cysteine-Rich Secretory Protein 3; CRISP-3; Specific Granule Protein of 28 kDa; SGP28; CRISP3	Human	HEK293
	The CRISP-3 protein interacts with A1BG, indicating a molecular association with potential functional implications. This suggests that CRISP-3 may be involved in processes associated with or regulated by A1BG. The specific nature and significance of this interaction require further elucidation, emphasizing the need for additional investigation into the molecular mechanisms and biological consequences of the CRISP-3 and A1BG interaction. CRISP-3 Protein, Human (HEK293, His) is the recombinant human-derived CRISP-3 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P79104

	PRDC/GREM2 Protein, Mouse Gremlin-2; Grem2; cysteine knot superfamily 1, BMP antagonist 2; Protein related to DAN and cerberus; PRDC; Cktsf1b2; Protein Related to DAN and Cerberus/Gremlin-2	Mouse	E. coli
	PRDC, encoded by the GREM2 gene, has multiple functions, including BMP and protein binding, which are critical for dorsal identity determination, embryoid body morphogenesis, and signal transduction regulation. PRDC is found extracellularly and is expressed in structures such as the cartilaginous skull, integument, intestinal smooth muscle annulus, lung, and neural tube. PRDC/GREM2 Protein, Mouse is the recombinant mouse-derived PRDC/GREM2 protein, expressed by E. coli , with tag free.

HY-P703404

	DHHC20 Protein, Human (Sf9) Palmitoyltransferase ZDHHC20; Acyltransferase ZDHHC20; 2.3.1.-; DHHC domain-containing cysteine-rich protein 20; DHHC20; Zinc finger DHHC domain-containing protein 20; ZDHHC20; Homo sapiens; Human; Acyltransferase; Transferase; 2.3.1.225	Human	Sf9 insect cells
	DHHC20 Protein, Human (Sf9) is the recombinant human-derived DHHC20, expressed by Sf9 insect cells , with tag Free labeled tag. The total length of DHHC20 Protein, Human (Sf9) is 365 a.a.,

HY-P7842

	CCN1/Cyr61 Protein, Human (HEK293, Fc) 1 Publications Verification rHuCCN family member 1/Cyr61, Fc; Protein CYR61; CCN family member 1; cysteine-rich angiogenic inducer 61; Insulin-like growth factor-binding protein 10 ; GIG1; CYR61; CCN1; IGFBP10;	Human	HEK293
	CCN1/Cyr61 proteins play critical roles in cellular processes, promoting cell proliferation, chemotaxis, angiogenesis, and adhesion. It coordinates wound healing by upregulating key genes related to angiogenesis, inflammation and matrix remodeling in skin fibroblasts and is heparin binding dependent. CCN1/Cyr61 Protein, Human (HEK293, Fc) is the recombinant human-derived CCN1/Cyr61 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CCN1/Cyr61 Protein, Human (HEK293, Fc) is 357 a.a., with molecular weight of 71-80 kDa.

HY-P703334

	ABCF3 Protein, Human (HEK293, His, Strep, Flag) ATP-binding cassette sub-family F member 3; ABCF3; Homo sapiens; Human	Human	HEK293
	ABCF3 Protein, Human (HEK293, His, Strep, Flag) is the recombinant human-derived ABCF3, expressed by HEK293 , with Strep, His, Flag labeled tag. The total length of ABCF3 Protein, Human (HEK293, His, Strep, Flag) is 708 a.a.,

HY-P7621

	ABCB5 Protein, Human (Trx) rHuABCB5, N-Trx; ATP-binding cassette sub-family B member 5; P-glycoprotein ABCB5; ABCB5	Human	E. coli
	ABCB5, N-Trx Protein, Human is a plasma membrane-spanning protein that in humans is encoded by the ABCB5 gene. ABCB5 is an ABC transporter and P-glycoprotein family member principally expressed in physiological skin and human malignant melanoma.

HY-P703309

	ABCA6 Protein, Human (HEK293, His, Strep, Flag) ATP-binding cassette sub-family A member 6; ABCA6; Homo sapiens; Human; Translocase	Human	HEK293
	ABCA6 Protein, Human (HEK293, His, Strep, Flag) is the recombinant human-derived ABCA6, expressed by HEK293 , with Strep, His, Flag labeled tag. The total length of ABCA6 Protein, Human (HEK293, His, Strep, Flag) is 1616 a.a.,

HY-P72201

	GAPDH Protein, Human (His-SUMO) G3P_HUMAN; G3PD; G3PDH; GAPD; GAPDH; Glyceraldehyde 3 phosphate dehydrogenase; glyceraldehyde 3-PDH; Glyceraldehyde-3-phosphate dehydrogenase; HEL-S-162eP; KNC-NDS6; MGC102544; OCAS; p38 component; OCT1 coactivator in S phase; 38-KD component; peptidyl cysteine S nitrosylase GAPDH	Human	E. coli
	GAPDH, a multifunctional protein, acts as a key enzyme in glycolysis, catalyzing the conversion of G3P. It also functions as a nitrosylase, impacting nuclear processes. In addition, it influences cytoskeleton organization, associates with CHP1, participates in transcript-selective translation inhibition, contributes to immune responses, and mediates nuclear events through S-nitrosylation of target proteins. GAPDH Protein, Human (His-SUMO) is the recombinant human-derived GAPDH protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P71142

	Serpin B3 Protein, Human (HEK293, His) Serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 3; Squamous cell carcinoma antigen 1; T4-A; SCCA1	Human	HEK293
	The Serpin B3 protein exhibits versatility in cellular regulation and may act as a papain-like cysteine protease inhibitor to modulate immune responses against tumor cells. Its dual role extends to inhibiting UV-induced apoptosis by inhibiting c-Jun NH(2)-terminal kinase (JNK1) activity, suggesting that Serpin B3 is involved in the stress response. Serpin B3 Protein, Human (HEK293, His) is the recombinant human-derived Serpin B3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin B3 Protein, Human (HEK293, His) is 390 a.a., with molecular weight of 41-50 kDa.

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Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-Y0337S5

*L-Cysteine-d3*
L-Cysteine-d₃ is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S6

*L-Cysteine-d2*
L-Cysteine-d₂ is the deuterium labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-Y0337S1

*L-Cysteine-15N*
L-Cysteine- ¹⁵N is the ¹⁵N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].

HY-146656S

*S-Sulfo-DL-cysteine-2,3,3-d3*
S-Sulfo-DL-cysteine-2,3,3-d₃ is the deuterium labeled S-Sulfo-DL-cysteine-2,3,3.

HY-151215S

*S-Sulfo-DL-cysteine-2,3,3-d3-1*
S-Sulfo-DL-cysteine-2,3,3-d₃-1 is the deuterium labeled S-Sulfo-DL-cysteine[1].

HY-139610S1

*3-Sulfo-glycodeoxycholic acid-d4 sodium*
3-Sulfo-glycodeoxycholic acid-d₄ (sodium) is the deuterium labeled 3-Sulfo-glycodeoxycholic acid[1].

HY-139610S

*3-Sulfo-glycodeoxycholic acid-d4 disodium*
3-Sulfo-glycodeoxycholic acid-d₄ (disodium) is the deuterium labeled 3-Sulfo-glycodeoxycholic acid disodium[1].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82724

	Legumain Antibody (YA2469) AEP; cysteine 1; Legumain; LGMN; LGMN1; PRSC1	WB	Human, Mouse, Rat
	Legumain Antibody (YA2469) is a biotin-conjugated non-conjugated IgG antibody, targeting Legumain, with a predicted molecular weight of 49 kDa (observed band size: 36,57 kDa). Legumain Antibody (YA2469) can be used for WB experiment in human, mouse, rat background.

HY-P80557

	ATG4A Antibody ATG4A; APG4A; AUTL2; cysteine protease ATG4A; AUT-like 2 cysteine endopeptidase; Autophagin-2; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; hAPG4A	WB, IHC-P, IP	Human
	ATG4A Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 45 kDa, targeting to ATG4A. It can be used for WB,IHC-P,IP assays with tag free, in the background of Human .

HY-P80558

	ATG4C Antibody ATG4C; APG4C; AUTL1; AUTL3; cysteine protease ATG4C; AUT-like 3 cysteine endopeptidase; Autophagin-3; Autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C	WB, IHC-P	Human
	ATG4C Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 52 kDa, targeting to ATG4C. It can be used for WB,IHC-P assays with tag free, in the background of Human.

HY-P83725

	ATG4C Antibody (YA3456) ATG4C; APG4C; AUTL1; AUTL3; cysteine protease ATG4C; AUT-like 3 cysteine endopeptidase; Autophagin-3; Autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C	WB, IP	Human, Mouse, Rat
	ATG4C Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 52 kDa, targeting to ATG4C. It can be used for WB,IP assays with tag free, in the background of Human,Rat,Mouse.

HY-P82707

	Cystathionase Antibody (YA2452) CTH; Cystathionine gamma lyase; cysteine desulfhydrase; Gamma cystathionase; Homoserine deaminase	WB, IP	Human
	Cystathionase Antibody (YA2452) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2452), targeting Cystathionase, with a predicted molecular weight of 45 kDa (observed band size: 42 kDa). Cystathionase Antibody (YA2452) can be used for WB, IP experiment in human background.

HY-P80935

	xCT Antibody (YA006) 3 Publications Verification CCBR1; cysteine/glutamate transporter; SLC7A11; solute carrier family 7; xCT	WB, IP	Human, Mouse
	xCT Antibody (YA006) is a non-conjugated and Rabbit origined monoclonal antibody about 55 kDa, targeting to xCT. It can be used for WB,IP assays with tag free, in the background of Human, Mouse.

HY-P81252

	Caspase-5 p20 Antibody Caspase-5 subunit p20; Apoptosis related cysteine protease; CASP 5; CASP5; Caspase-5; Caspase5; Caspase 5 apoptosis related cysteine peptidase; caspase 5 apoptosis related cysteine protease; ICE; ICE(rel) III; ICE(rel)III; ICEREL III; ICERELIII; ICH 3; ICH 3 protease; ICH3; ICH3 protease; MGC141966; TY; TY protease.	WB, IHC-P, IHC-F, ICC/IF, ELISA	Human, Mouse
	Caspase-5 p20 Antibody is a rabbit-derived non-conjugated IgG antibody, targeting Caspase-5 p20, with a predicted molecular weight of 48 kDa. Caspase-5 p20 Antibody can be used for WB, IHC-P, IHC-F, ICC/IF, ELISA experiments in human, mouse backgrounds.

HY-P82352

	Angiotensinogen Antibody (YA2097) Angiotensinogen; Serpin A8; AGT; SERPINA8; Des-Asp[1]-angiotensin II; Serine (or cysteine) proteinase inhibitor	WB, IHC-P, IP	Mouse
	Angiotensinogen Antibody (YA2097) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2097), targeting Angiotensinogen, with a predicted molecular weight of 52 kDa (observed band size: 52 kDa). Angiotensinogen Antibody (YA2097) can be used for WB, IHC-P, IP experiment in mouse background.

HY-P81662

	GCLM Antibody (YA1407) GCLM; GLCLR; Glutamate--cysteine ligase regulatory subunit; GCS light chain; Gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Glutamate--cysteine ligase modifier subunit	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	GCLM Antibody (YA1407) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1407), targeting GCLM, with a predicted molecular weight of 31 kDa (observed band size: 31 kDa). GCLM Antibody (YA1407) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P82723

	ATG4B Antibody (YA2468) ATG4B; APG4B; AUTL1; KIAA0943; cysteine protease ATG4B; AUT-like 1 cysteine endopeptidase; Autophagin-1; Autophagy-related cysteine endopeptidase 1; Autophagy-related protein 4 homolog B; hAPG4B	WB, FC	Human, Mouse, Rat
	ATG4B Antibody (YA2468) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2468), targeting ATG4B, with a predicted molecular weight of 44 kDa (observed band size: 44 kDa). ATG4B Antibody (YA2468) can be used for WB, FC experiment in human, mouse, rat background.

HY-P83153

	GCLC Antibody (YA2898) GCLC; GLCL; GLCLC; Glutamate--cysteine ligase catalytic subunit; GCS heavy chain; Gamma-ECS; Gamma-glutamylcysteine synthetase	WB	Human, Mouse, Rat
	GCLC Antibody (YA2898) is a biotin-conjugated non-conjugated IgG antibody, targeting GCLC, with a predicted molecular weight of 73 kDa (observed band size: 73 kDa). GCLC Antibody (YA2898) can be used for WB experiment in human, mouse, rat background.

HY-P81457

	SPARC Antibody (YA1202) SPARC; ON; SPARC; Basement-membrane protein 40; BM-40; Osteonectin; ON; Secreted protein acidic and rich in cysteine	IHC-P	Human
	SPARC Antibody (YA1202) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1202), targeting SPARC. SPARC Antibody (YA1202) can be used for IHC-P experiment in human background.

HY-P80725

	iNOS Antibody NOS2; NOS2A; Nitric oxide synthase; inducible; Hepatocyte NOS; HEP-NOS; Inducible NO synthase; Inducible NOS; iNOS; NOS type II; Peptidyl-cysteine S-nitrosylase NOS2	WB, IHC-P, IHC-F, ICC/IF	Human, Mouse, Rat
	iNOS Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 131 kDa, targeting to iNOS. It can be used for ICC/IF,WB,IHC-F,IHC-P,ELISA assays with tag free, in the background of Human, Mouse, Rat.

HY-P81251

	CASP4 Antibody Caspase-4 subunit 2; Caspase-4 subunit p10; Caspase-11; CASP-11; Protease ICH-3; Apoptosis related cysteine peptidase; Apoptotic cysteine protease Mih1/TX; CASP 4; CASP 4; CASP-4; CASP4; CASP4_HUMAN; CASP4_MOUSE; Caspase 4 apoptosis related cysteine peptidase; Caspase-4 subunit 2; Caspase4; ICE(rel) II; ICE(rel)-II; ICE(rel)II; ICEREL II; ICERELII; ICH 2; ICH 2 protease; ICH2; Mih1/TX; Mih1/TX; Protease ICH-2; Protease TX; TX; TX protease; EC:3.4.22.64.	WB, ELISA	Human, Rat
	CASP4 Antibody is a biotin-conjugated non-conjugated IgG antibody, targeting CASP4, with a predicted molecular weight of 43 kDa. CASP4 Antibody can be used for WB, ELISA experiment in human and rat background.

HY-P80623

	Cleaved-Caspase 3 p12 Antibody CASP3; CPP32; Caspase-3; CASP-3; Apopain; cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1	WB, ICC/IF	Human, Mouse, Rat
	Cleaved-Caspase 3 p12 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 32 kDa, targeting to Cleaved-Caspase 3 p12. It can be used for WB,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P81528

	LMO2 Antibody (YA1273) LMO2; RBTN2, RBTNL1, RHOM2, TTG2; Rhombotin-2; cysteine-rich protein TTG-2; LIM domain only protein 2 (LMO-2); T-cell translocation protein 2	IHC-P	Human
	LMO2 Antibody (YA1273) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1273), targeting LMO2. LMO2 Antibody (YA1273) can be used for IHC-P experiment in human background.

HY-P81177

	CD163 Antibody Scavenger receptor cysteine-rich type 1 protein M130; CD 163; CD163 antigen; CD163 molecule; Hemoglobin Scavenger Receptor; M130; M130 antigen precursor; Macrophage associated antigen; MM130; C163A_HUMAN.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse
	CD163 Antibody is an unconjugated, approximately 130 kDa, rabbit-derived, anti-CD163 polyclonal antibody. CD163 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, mouse, and predicted: rat, dog, pig, horse background without labeling.

HY-P80624

	Cleaved-Caspase 8 Antibody CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	Cleaved-Caspase 8 Antibody is a non-conjugated and Mouse origined monoclonal antibody about 55 kDa, targeting to Cleaved-Caspase 8. It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P83063

	TRAF4 Antibody (YA2808) TRAF4; CART1; MLN62; RNF83; TNF receptor-associated factor 4; cysteine-rich domain associated with RING and Traf domains protein 1; Metastatic lymph node gene 62 protein; MLN 62; RING finger protein 83	WB, ICC/IF, FC	Human, Mouse
	TRAF4 Antibody (YA2808) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2808), targeting TRAF4, with a predicted molecular weight of 54 kDa (observed band size: 54 kDa). TRAF4 Antibody (YA2808) can be used for WB, ICC/IF, FC experiment in human, mouse background.

HY-P80527

	ABCB5 Antibody (YA836) ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5	WB, ICC/IF	Human
	ABCB5 Antibody (YA836) is a non-conjugated and Mouse origined monoclonal antibody about 139 kDa, targeting to ABCB5 (8D2). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

HY-P81232

	Caspase-1 p20 Antibody caspase-1 isoform alpha p20 subunit; CASP1; ICE; IL1BC; Caspase-1 subunit p20; CASP 1; Caspase 1 apoptosis related cysteine peptidase; Caspase 1 apoptosis related cysteine protease; Caspase1; IL 1 beta converting enzyme; IL 1BC; IL1B convertase; IL1BCE; Interleukin 1 beta convertase; Interleukin 1 beta convertase precursor; Interleukin 1 beta converting enzyme; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; CASP1_HUMAN; CASP1_MOUSE.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse, Rat,
	Caspase-1 p20 Antibody is an unconjugated, approximately 46 kDa, rabbit-derived, anti-Caspase-1 p20 polyclonal antibody. Caspase-1 p20 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, mouse, rat, background without labeling.

HY-P81161

	CEBP-alpha Antibody Apoptotic cysteine protease; Apoptotic protease Mch 5; C/EBP alpha; CAP4; Caspase 8 precursor; CCAAT Enhancer Binding Protein alpha; CEBP; CEBP A; CEBP alpha; CEBPA; FADD homologous ICE/CED 3 like protease; FADD like ICE; FLICE; ICE like apoptotic protease 5; ICE8; MACH; MCH5; MORT1 associated CED 3 homolog; CEBP α, CEBP-α.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human, Rat
	CEBP-alpha Antibody is an unconjugated, approximately 39 kDa, rabbit-derived, anti-CEBP-alpha polyclonal antibody. CEBP-alpha Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, rat, and predicted: mouse, dog, pig, cow, rabbit, sheep, goat background without labeling.

HY-P80772

	P Glycoprotein Antibody p-pg; PGP; ABCB1; MDR1; PGY1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD antigen CD243	WB	Human
	P Glycoprotein Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 141 kDa, targeting to P Glycoprotein. It can be used for WB assays with tag free, in the background of Human.

HY-P81118

	MRP2 Antibody ABC30 antibody; abcC2 antibody; ATP binding cassette sub family C (CFTR/MRP) member 2 antibody; ATP binding cassette subfamily C member 2 antibody; ATP-binding cassette sub-family C member 2 antibody; Canalicular multidrug resistance protein antibody; Canalicular multispecific organic anion transporter 1 antibody; CMOAT antibody; CMOAT1 antibody; cMRP antibody; DJS antibody; KIAA1010 antibody; MRP 2 antibody; MRP2_HUMAN antibody; Multidrug resistance associated protein 2 antibody; Multidrug resistance-associated protein 2 antibody;	WB, ICC/IF, FC	Human
	MRP2/ABCC2 Antibody is an unconjugated, approximately 174 kDa, rabbit-derived, anti-MRP2/ABCC2 monoclonal antibody. MRP2/ABCC2 Antibody can be used for: WB, ICC/IF, FC expriments in human background without labeling.

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Cat. No.
Host
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Application
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Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-123687

*DBCO-Sulfo-NHS ester sodium*		ADC Synthesis DBCO
DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-NHS ester (sodium) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-151789

Sulfo DBCO-TFP Ester		DBCO
Sulfo DBCO-TFP Ester is a water-soluble, sulfo-containing click chemistry reagent. Sulfo DBCO-TFP Ester enables simple and efficient incorporation of sulfo-DBCO moieties onto amine-containing molecules .

HY-W123028

Sulfo-SANPAH sodium		Azide
Sulfo-SANPAH (sodium) is a biochemical reagent .

HY-D2241

Sulfo-Cy7-DBCO		DBCO
Sulfo-Cy7-DBCO is the water-soluble version of cyanine 7. Sulfo-Cy7-DBCO spectral properties are similar to Cy7. Sulfo-Cy7-DBCO is a near-infrared fluorescent dye .

HY-D1598

Sulfo-CY3 tetrazine potassium		Labeling and Fluorescence Imaging Tetrazine
Sulfo-CY3 tetrazine potassium is a sulfo-Cyanine3 derivative that contains methyltetrazine moiety (Ex=548 nm, Em=563 nm). Sulfo-CY3 tetrazine potassium can be used for the labeling of metabolically engineered cell-surface glycoconjugates . Sulfo-CY3 tetrazine (potassium) is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-151712

Sulfo-Cy5-Methyltetrazine		Tetrazine Labeling and Fluorescence Imaging
Sulfo-Cy5-Methyltetrazine is a click chemistry reagent containing a methyltetrazine group. Sulfo-Cy5-Methyltetrazine acts as a fluorophore linker for trans-cyclooctene-based labeling. Sulfo-Cy5-Methyltetrazine shows good stability at physiological pH and is also highly reactive towards cyclooctene.

HY-151713

Sulfo-Cy3-Methyltetrazine		Labeling and Fluorescence Imaging Tetrazine
Sulfo-Cy3-Methyltetrazine (figure 7 compound 5) is a click chemistry reagent containing methyltetrazine and a water-soluble dye. Sulfo-Cy3-Methyltetrazine shows good stability at physiological pH. Sulfo-Cy3-Methyltetrazine can be coupled to trans-cyclooctene and is also highly reactive towards cyclooctene .

HY-127056

Sulfo DBCO-amine		PROTAC Synthesis DBCO
Sulfo DBCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-140306

*Mal-Sulfo-DBCO*		DBCO ADC Synthesis
Mal-Sulfo-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Mal-Sulfo-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-D2219

Sulfo-Cy7 tetrazine		Tetrazine
Sulfo-Cy7 tetrazine is a near-infrared water-soluble fluorophore. Sulfo-Cy7 tetrazine contains the methyltetrazine group for rapid, efficient, and metal-free conjugation to cycloolefin in a reaction called TCO linkage .

HY-151759

Sulfo-Cy5-TCO		TCO Labeling and Fluorescence Imaging
Sulfo-Cy5-TCO is a click chemistry reagent containing a TCO group. Sulfo-Cy5-TCO is water soluble dye, which is highly reactive with tetrazines and methyltetrazines with the fastest bioconjugation speed .

HY-141268

*Methyltetrazine-Sulfo-NHS ester sodium*		Tetrazine
Methyltetrazine-Sulfo-NHS ester (sodium) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-145746

Sulfo-Cy5 azide		Labeling and Fluorescence Imaging Azide
Sulfo-Cy5 azide is a fluorescent dye and nontargeted contrast agent. Sulfo-Cy5 azide has been used to label and image RNA . Sulfo-Cy5 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-130810

*DBCO-Sulfo-Link-biotin*		DBCO ADC Synthesis
DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Sulfo-Link-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

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