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Results for "

peptide-1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (14) CGRP Receptor (2) Formyl Peptide Receptor (FPR) (2) ADC Linker (1) Amino Acid Derivatives (7) Angiotensin Receptor (6) Angiotensin-converting Enzyme (ACE) (3) Antibiotic (1) Apoptosis (3) Bacterial (4) Bcl-2 Family (1) Biochemical Assay Reagents (7) Calmodulin (1) Cathepsin (1) CD47 (1) Cholinesterase (ChE) (1) Complement System (1) Deubiquitinase (1) Dipeptidyl Peptidase (9) Endogenous Metabolite (5) FAAH (1) Fluorescent Dye (5) Fungal (1) Gap Junction Protein (2) GCGR (61) GLP Receptor (31) GnRH Receptor (3) GPR119 (2) GPR35 (1) GSK-3 (3) HCV (2) HCV Protease (2) Histamine Receptor (1) HIV (1) IFNAR (1) Insulin Receptor (1) Integrin (2) Interleukin Related (2) Isotope-Labeled Compounds (3) Liposome (1) NOD-like Receptor (NLR) (2) Opioid Receptor (1) p38 MAPK (2) PKC (1) Protease Activated Receptor (PAR) (5) Proteasome (1) SARS-CoV (2) Src (1) Tau Protein (1) TGF-beta/Smad (2) TRP Channel (1) Vasopressin Receptor (1)
By Research Areas:	Cancer (18) Cardiovascular Disease (19) Endocrinology (6) Infection (12) Inflammation/Immunology (14) Metabolic Disease (103) Neurological Disease (40)
Click Chemistry:	TCO (1)
Oligonucleotides:	Phospholipids (1) Polymers (2)

202

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

198

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

*Proteasome-activating peptide 1* TFA** 1 Publications Verification	Proteasome	Neurological Disease
Proteasome-activating peptide 1 TFA is a peptide and a potent proteasome activator. Proteasome-activating peptide 1 TFA increases the chymotrypsin-like proteasomal catalytic activity and, consequently, proteolytic rates both in vitro and in culture. Proteasome-activating peptide 1 TFA prevents protein aggregation in a cellular model of amyotrophic lateral sclerosis ^[1].

*Glucagon-like peptide 1* (1-37), human TFA** 1 Publications Verification HuGLP-1 TFA	GCGR	Metabolic Disease
Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor.

*IL-23R inhibitor peptide-1*	Interleukin Related	Inflammation/Immunology
IL-23R inhibitor peptide-1 (comp 475) is an interleukin-23 receptor inhibitor, with an IC₅₀ of 0.0069 μM ^[1].

Tyrosine Kinase Peptide 1	Src	Others
Tyrosine Kinase Peptide 1 is a control substrate peptide for c-Src assay ^[1].

Calmodulin Binding Peptide 1	Calmodulin	Neurological Disease
Calmodulin Binding Peptide 1 is a high affinity (pM) CaM-binding peptide derived from smooth muscle myosin light-chain kinase (MLCK peptide), which strongly inhibits IP3-induced Ca ²⁺ release ^[1].

IFN-α Receptor Recognition Peptide 1 IRRP1	IFNAR	Infection
IFN-α Receptor Recognition Peptide 1 is a peptide of IFN-α associated with receptor interactions ^[1].

*Biotin-Glucagon-Like Peptide 1* (7-36) amide, human**	Fluorescent Dye	Others
Biotin-Glucagon-Like Peptide 1 (7-36) amide, human is a biologically active peptide. Biotin-Glucagon-Like Peptide 1 (7-36) amide, human can be used for the research of various biochemical studies.

Klotho-derived peptide 1 KP1 (human)	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model ^[1].

*Klotho-derived peptide 1* hydrochloride** KP1 (human) hydrochloride	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) hydrochloride blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model ^[1].

*Glucagon-like peptide 1* (1-37), human** HuGLP-1	GCGR	Metabolic Disease
Glucagon-like peptide 1 (1-37), human is a highly potent agonist of the GLP-1 receptor.

*Glucagon-Like Peptide 1* (GLP-1) (7-36)-Lys (Biotin), amide, human**	GLP Receptor	Metabolic Disease
Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human is an C-terminal-labelled biotinylated GLP-1 (7-36) amide.

Cochinchinenin C	GCGR	Metabolic Disease
Cochinchinenin C is a nonpolypeptide agonist of *glucagon-like peptide-1* (GLP-1) receptor**. Cochinchinenin C can be used for the research of diabetes ^[1] .

GLP-1 (1-36) amide (human, rat) Glucagon-like peptide 1 (1-36) amide (human, rat)	GLP Receptor GCGR	Metabolic Disease
GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat) ) is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells ^[1].

GLP-1 (1-36) amide (human, rat) (TFA) Glucagon-like peptide 1 (1-36) amide (human, rat) (TFA)	GLP Receptor GCGR	Metabolic Disease
GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat) ) TFA is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) TFA can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells ^[1].

Dulaglutide 1 Publications Verification LY2189265	GCGR	Metabolic Disease
Dulaglutide (LY2189265) is a glucagon-like peptide-1 (GLP-1) receptor agonist. Dulaglutide can be uesd for the research of type 2 diabetes (T2D) ^[1] .

HKPao Hunter-killer peptide ao; Prohibitin-targeting peptide 1; prohibitin-TP01; Adipotide	Apoptosis	Cancer
HKPao (Hunter-killer peptide ao) is a biologically active peptide. HKPao (Hunter-killer peptide ao) has anti-obesity and anti-tumor pro-apoptotic activity to cause release of cytochrome c from vesicles ^[1].

2-Oleoylglycerol	GPR119	Metabolic Disease
2-Oleoylglycerol is a dietary naturally occurring lipid. 2-Oleoylglycerol is a GPR119 agonist, with an EC₅₀ of 2.5 μM for human GPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol stimulates glucagon-like peptide-1 (GLP-1) secretion in vivo ^[1] .

Des His1, Glu8 Exendin-4	GCGR	Metabolic Disease
Des His1, Glu8 Exendin-4 is a potent glucagon-like peptide-1 receptor (GLP-1-R) antagonist. Des His1, Glu8 Exendin-4 improves glucose homeostasis by regulating both insulin secretion and glucose production. Des His1, Glu8 Exendin-4 can be used for the research of type 2 diabetic and gastrointestinal ^[1].

Retatrutide 1 Publications Verification LY3437943	GCGR GLP Receptor	Metabolic Disease
Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds human GCGR, GIPR, and GLP-1R with EC₅₀ values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity ^[1].

Retatrutide acetate LY3437943 acetate	GCGR GLP Receptor	Metabolic Disease
Retatrutide (LY3437943) acetate is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC₅₀ values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide acetate can be used for the research of obesity ^[1].

Exendin-4 (3-39)	GCGR	Neurological Disease Endocrinology
Exendin-4 (3-39) is a *peptide. Exendin-4 (3-39) is a truncated form of Exendin-4 (HY-13443) that lacks the first two amino acids. Exendin-4 is a potent Glucagon-like peptide-1* receptor (GLP-1r) agonist. Exendin-4 (3-39) and Exendin-4 can be used for the research of diabetic and hypothalamic-pituitary-adrenal (HPA) axis ^[1] .

Retatrutide TFA 1 Publications Verification LY3437943 TFA	GLP Receptor GCGR	Metabolic Disease
Retatrutide (LY3437943) TFA is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide TFA binds human GCGR, GIPR, and GLP-1R with EC₅₀ values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide TFA can be used for the research of obesity ^[1].

Liraglutide 20+ Cited Publications	GCGR GLP Receptor	Metabolic Disease
Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.

GLP-1 receptor agonist 2	GCGR	Others
GLP-1 receptor agonist 2 is a glucagon-like peptide-1 receptor *(GLP-1R)* agonist.

LSN3318839	GCGR	Metabolic Disease
LSN3318839 is an orally efficacious positive allosteric modulator of the glucagon-like peptide-1 receptor (GLP-1R).

I-070	GLP Receptor	Metabolic Disease
I-070 is an agonist for glucagon-like peptide-1 receptor (GLP-1 receptor), with EC₅₀ of 0.0187 nM ^[1].

I-128	GLP Receptor	Metabolic Disease
I-128 is an agonist for glucagon-like peptide-1 receptor (GLP-1 receptor), with EC₅₀ of 0.0122 nM ^[1].

Albiglutide fragment TFA GLP-1-Gly8 TFA; GLP-1 (7-36) analog TFA	GLP Receptor	Metabolic Disease
Albiglutide fragment (GLP-1 (7-36) analog) TFA is an active fragment of Albiglutide (7-36) and a glucagon-like peptide-1 (GLP-1) analog (a long-acting *GLP-1* receptor agonist). Albiglutide is produced by the fusion of DPP-4 resistant GLP-1 dimer with the human albumin gene. Moreover, Albiglutide fragment TFA significantly reduces glycosylated hemoglobin (A1C) and is used in type 2 diabetes (T2D) studies ^[1] .

Albiglutide fragment GLP-1-Gly8; GLP-1 (7-36) analog	GLP Receptor	Metabolic Disease
Albiglutide fragment (GLP-1 (7-36) analog) is an active fragment of Albiglutide (7-36) and a glucagon-like peptide-1 (GLP-1) analog (a long-acting *GLP-1* receptor agonist). Albiglutide is produced by the fusion of DPP-4 resistant GLP-1 dimer with the human albumin gene. Moreover, Albiglutide fragment significantly reduces glycosylated hemoglobin (A1C) and is used in type 2 diabetes (T2D) studies ^[1] .

Exendin-4 Maximum Cited Publications 45 Publications Verification Exenatide	GCGR	Metabolic Disease
Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC₅₀ of 3.22 nM.

Exendin-4 acetate Maximum Cited Publications 45 Publications Verification Exenatide acetate	GCGR	Metabolic Disease
Exendin-4 acetate (Exenatide acetate), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC₅₀ of 3.22 nM.

GLP-1(7-36), amide acetate 5+ Cited Publications Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate; Human GLP-1 (7-36), amide acetate	GCGR	Metabolic Disease
GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.

GLP-1(7-36), amide Glucagon-like peptide-1 (GLP-1)(7-36), amide; Human GLP-1 (7-36), amide	GCGR	Metabolic Disease
GLP-1(7-36), amide is a physiological incretin hormone that stimulates insulin secretion.

Pegloxenatide PEX 168	GLP Receptor	Metabolic Disease
Pegloxenatide is a *glucagon-like peptide-1* receptor (GLP-1 RA) agonist. Pegloxenatide can be used for type 2 diabetes** research ^[1].

Lixisenatide acetate 2 Publications Verification	GCGR	Metabolic Disease
Lixisenatide acetate is a *glucagon-like peptide-1* (GLP-1) receptor** agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM).

Semaglutide 4 Publications Verification	GCGR	Metabolic Disease
Semaglutide, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 *(GLP-1)* receptor agonist. Semaglutide has the potential for type 2 diabetes treatment.

Semaglutide acetate 4 Publications Verification	GCGR	Metabolic Disease
Semaglutide acetate, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 *(GLP-1)* receptor agonist. Semaglutide acetate has the potential for type 2 diabetes treatment.

GLP-1R agonist 26	GLP Receptor	Metabolic Disease
GLP-1R agonist 26 (compound 1) is a glucagon-like peptide-1 receptor (GLP-1R) agonist with an EC₅₀ of <10 nM ^[1].

*C-Peptide 1* (rat)**	GSK-3	Cancer
C-Peptide 1 (rat), a peptide, is aβ-catenin/GSK-3β activator. C-Peptide 1 (rat) can regulate the Wnt/β-catenin signaling pathway. C-Peptide 1 (rat) can be used for the research of cancer ^[1].

BETP 1 Publications Verification	GCGR	Metabolic Disease
BETP is an agonist of *glucagon-like peptide-1* (GLP-1) receptor, with EC₅₀*s of 0.66 and 0.755 μM for human and rat GLP*-1 receptor, respectively.

Semaglutide TFA 4 Publications Verification	GCGR	Metabolic Disease
Semaglutide TFA, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 *(GLP-1)* receptor agonist. Semaglutide TFA has the potential for type 2 diabetes treatment.

Pal-Glu(OSu)-OH	GLP Receptor	Others
Pal-Glu(OSu)-OH is a side chain of Liraglutide. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used for type 2 diabetes mellitus research ^[1].

Eicosapentaenoyl serotonin EPA-5-HT	FAAH	Metabolic Disease
Eicosapentaenoyl serotonin (EPA-5-HT) is an N-acyl serotonin, a novel lipid present in the gut. Eicosapentaenoyl serotonin inhibits glucagon-like peptide-1 secretion and FAAH activity ^[1].

GLP-1R agonist 20	GLP Receptor	Metabolic Disease
GLP-1R agonist 20 (Compound I-132) is an agonist for glucagon-like peptide-1 receptor (GLP-1 receptor), with EC₅₀ of 0.0162 nM ^[1].

GLP-1R agonist 21	GLP Receptor	Metabolic Disease
GLP-1R agonist 21 (Compound I-134) is an agonist for glucagon-like peptide-1 receptor (GLP-1 receptor), with EC₅₀ of 0.0104 nM ^[1].

GLP-1R agonist 22	GLP Receptor	Metabolic Disease
GLP-1R agonist 22 (Compound I-135) is an agonist for glucagon-like peptide-1 receptor (GLP-1 receptor), with EC₅₀ of 0.0165 nM ^[1].

Cat. No.	Product Name	Type

HY-114118F

Semaglutide, FITC labeled	Fluorescent Dyes/Probes
Semaglutide, FITC labeled is a FITC labeled Semaglutide. Semaglutide, a long-acting *GLP-1* alogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide has the potential for type 2 diabetes treatment ^[1].

HY-P1363F3

5-FAM-β-Amyloid (1-42), human Tris 5-FAM-Amyloid β-peptide (1-42) (human) Tris	Fluorescent Dyes/Probes
5-FAM-β-Amyloid (1-42), human (5-FAM-Amyloid β-peptide (1-42) (human) TFA is a5-FAM labeled β-Amyloid (1-42), human TFA (HY-P1363).

HY-D1423

Dibromobimane	Fluorescent Dyes/Probes
Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides .

HY-W039519

7-Methoxycoumarin-3-carboxylic acid	Fluorescent Dyes/Probes
7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye with an excitation peak at 355 nm and an emission peak at 405 nm. 7-Methoxycoumarin-3-carboxylic acid can be used to label peptide .

HY-D1592

BODIPY TMR C5-maleimide	Fluorescent Dyes/Probes
BODIPY TMR C5-maleimide is a fluorescent dye. BODIPY TMR C5-maleimide is a high quantum yield fluorophore which can be coupled with peptides .

Cat. No.	Product Name	Type

HY-D0878

TAPSO	Biochemical Assay Reagents
TAPSO is a common biological buffer, a pH stabilization reagent, with effective pH ranging from 7-8, and pKa values ranging from 7.5–9.0. TAPSO contains Tris groups and exhibits quite reactive activity with zwitterionic glycine peptides .

HY-Y0623

N-Hydroxysuccinimide HOSu; 1-Hydroxy-2,5-pyrrolidinedione	Biochemical Assay Reagents
N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is an activated ester commonly used in bioconjugation technologies such as protein labeling with fluorescent dyes and enzymes, chromatography supports, beads, nanoparticles, and microarrays Surface activation of glass slides, and chemically synthesized peptides .

HY-134393B

6-Me-ATP trisodium N6-Methyl-ATP trisodium	Gene Sequencing and Synthesis
6-Me-ATP (N6-Methyl-ATP) trisodium is a N ⁶-modified ATP derivative. 6-Me-ATP trisodium shows excellent binding affinity to GSK3, serving as the phosphate group donor for GSK3β-catalyzed phosphorylation of its substrate peptide .

HY-126437A

Poly-L-lysine hydrochloride

Drug Delivery

Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide. .

HY-158083

Polymethacrylate Copolymer	Drug Delivery
Polymethacrylate Copolymer forms nanodiscs spontaneously by fragmentation or solubilization of the lipid bilayers.Polymethacrylate Copolymer is used in designing of nanodisc-forming polymer to mimic the amphiphilic nature of proteins and peptides .

Cat. No.	Product Name	Target	Research Area

HY-P0122B

*iRGD peptide 1* TFA**	Peptides	Cancer
iRGD peptide 1 TFA is the prototypic tumor-specific tissue-penetrating peptide, which delivers agents deep into extravascular tumor tissue. iRGD peptide 1 TFA has anti-metastatic activity ^[1].

HY-P3414A

*Proteasome-activating peptide 1* TFA** 1 Publications Verification	Proteasome	Neurological Disease
Proteasome-activating peptide 1 TFA is a peptide and a potent proteasome activator. Proteasome-activating peptide 1 TFA increases the chymotrypsin-like proteasomal catalytic activity and, consequently, proteolytic rates both in vitro and in culture. Proteasome-activating peptide 1 TFA prevents protein aggregation in a cellular model of amyotrophic lateral sclerosis ^[1].

HY-P3756

*EPO mimetic peptide-1* EMP-1	Peptides	Inflammation/Immunology
EPO mimetic peptide-1 (EMP-1), a 20 amino acid peptide. EPO mimetic peptide-1 stimulates cell proliferation, affects cell cycle and induces the production of reticulocytes in vivo ^[1].

HY-P10383

*SPSB2-iNOS inhibitory cyclic peptide-1*	Peptides	Infection
SPSB2-iNOS inhibitory cyclic peptide-1 is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with K_D of 4.4 nM. SPSB2-iNOS inhibitory cyclic peptide-1 is resistant to the proteases pepsin, trypsin and α-chymotrypsin. SPSB2-iNOS inhibitory cyclic peptide-1 is stable in human plasma and in oxidative environment ^[1].

HY-P10723

*IL-23R inhibitor peptide-1*	Interleukin Related	Inflammation/Immunology
IL-23R inhibitor peptide-1 (comp 475) is an interleukin-23 receptor inhibitor, with an IC₅₀ of 0.0069 μM ^[1].

HY-P10383A

*SPSB2-iNOS inhibitory cyclic peptide-1 TFA*	Peptides	Infection
SPSB2-iNOS inhibitory cyclic peptide-1 TFA is the TFA salt form of SPSB2-iNOS inhibitory cyclic peptide-1(HY-P10383). SPSB2-iNOS inhibitory cyclic peptide-1 is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with K_D of 4.4 nM. SPSB2-iNOS inhibitory cyclic peptide-1 is resistant to the proteases pepsin, trypsin and α-chymotrypsin. SPSB2-iNOS inhibitory cyclic peptide-1 is stable in human plasma and in oxidative environment ^[1].

HY-P3712

Cardioexcitatory peptide 1	Peptides	Cardiovascular Disease Neurological Disease
Cardioexcitatory peptide 1 is a cardioexcitatory neuropeptide, can be isolated from Achatina atria. Cardioexcitatory peptide 1 has potent cardio-excitatory action on the hearts and also modifies the motility of muscular tissues and neural activities ^[1].

HY-P3414

Proteasome-activating peptide 1	Peptides	Neurological Disease
Proteasome-activating peptide 1 is a peptide, which increases the chymotrypsin-like proteasomal catalytic activity and, consequently, proteolytic rates both in vitro and in culture. Proteasome-activating peptide 1 prevents protein aggregation in a cellular model of amyotrophic lateral sclerosis ^[1].

HY-P2547

Tyrosine Kinase Peptide 1	Src	Others
Tyrosine Kinase Peptide 1 is a control substrate peptide for c-Src assay ^[1].

HY-P1805

Calmodulin Binding Peptide 1	Calmodulin	Neurological Disease
Calmodulin Binding Peptide 1 is a high affinity (pM) CaM-binding peptide derived from smooth muscle myosin light-chain kinase (MLCK peptide), which strongly inhibits IP3-induced Ca ²⁺ release ^[1].

HY-P0277

Carcinoembryonic antigen peptide 1 CEA peptide	Peptides	Cancer
Carcinoembryonic antigen peptide 1 (CEA peptide) is a carcinoembryonic antigen (CEA)-derived peptide. Carcinoembryonic antigen peptide 1 is a potential HLA-A*0201-restricted CTL epitope that can be used for the study of CTL-mediated epithelial-derived cancers ^[1].

HY-P10504

C-Terminally encoded peptide 1 CEP1	Peptides	Others
C-Terminally encoded peptide 1 (CEP1) is a small secreted peptide hormone. C-Terminally encoded peptide 1 is involved in regulating plant growth and abiotic stresses through cellular communication. C-Terminally encoded peptide 1 can be used in the study of plant growth and development ^[1].

HY-P1758

IFN-α Receptor Recognition Peptide 1 IRRP1	IFNAR	Infection
IFN-α Receptor Recognition Peptide 1 is a peptide of IFN-α associated with receptor interactions ^[1].

HY-P3623

*Biotin-Glucagon-Like Peptide 1* (7-36) amide, human**	Fluorescent Dye	Others
Biotin-Glucagon-Like Peptide 1 (7-36) amide, human is a biologically active peptide. Biotin-Glucagon-Like Peptide 1 (7-36) amide, human can be used for the research of various biochemical studies.

HY-P10414

Klotho-derived peptide 1 KP1 (human)	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model ^[1].

HY-P10414A

*Klotho-derived peptide 1* hydrochloride** KP1 (human) hydrochloride	TGF-beta/Smad p38 MAPK	Inflammation/Immunology
Klotho-derived peptide 1 (KP1 human) hydrochloride blocks TGF-β/TGF-β receptor 2 interaction, inhibits TGF-β-induced activation of Smad2/3 and mitogen-activated protein kinase (MAPK), and exhibits anti-fibrotic and kidney protective effects in mouse model ^[1].

HY-P1145

*Glucagon-like peptide 1* (1-37), human** HuGLP-1	GCGR	Metabolic Disease
Glucagon-like peptide 1 (1-37), human is a highly potent agonist of the GLP-1 receptor.

HY-P1145A

*Glucagon-like peptide 1* (1-37), human TFA** 1 Publications Verification HuGLP-1 TFA	GCGR	Metabolic Disease
Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor.

HY-P2535

*Glucagon-Like Peptide 1* (GLP-1) (7-36)-Lys (Biotin), amide, human**	GLP Receptor	Metabolic Disease
Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human is an C-terminal-labelled biotinylated GLP-1 (7-36) amide.

HY-P5815

GLP-1 (1-36) amide (human, rat) Glucagon-like peptide 1 (1-36) amide (human, rat)	GLP Receptor GCGR	Metabolic Disease
GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat) ) is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells ^[1].

HY-P5815A

GLP-1 (1-36) amide (human, rat) (TFA) Glucagon-like peptide 1 (1-36) amide (human, rat) (TFA)	GLP Receptor GCGR	Metabolic Disease
GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat) ) TFA is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) TFA can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells ^[1].

HY-P0120

Dulaglutide 1 Publications Verification LY2189265	GCGR	Metabolic Disease
Dulaglutide (LY2189265) is a glucagon-like peptide-1 (GLP-1) receptor agonist. Dulaglutide can be uesd for the research of type 2 diabetes (T2D) ^[1] .

HY-P3586

HKPao Hunter-killer peptide ao; Prohibitin-targeting peptide 1; prohibitin-TP01; Adipotide	Apoptosis	Cancer
HKPao (Hunter-killer peptide ao) is a biologically active peptide. HKPao (Hunter-killer peptide ao) has anti-obesity and anti-tumor pro-apoptotic activity to cause release of cytochrome c from vesicles ^[1].

HY-P3542

Des His1, Glu8 Exendin-4	GCGR	Metabolic Disease
Des His1, Glu8 Exendin-4 is a potent glucagon-like peptide-1 receptor (GLP-1-R) antagonist. Des His1, Glu8 Exendin-4 improves glucose homeostasis by regulating both insulin secretion and glucose production. Des His1, Glu8 Exendin-4 can be used for the research of type 2 diabetic and gastrointestinal ^[1].

HY-P3506

Retatrutide 1 Publications Verification LY3437943	GCGR GLP Receptor	Metabolic Disease
Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds human GCGR, GIPR, and GLP-1R with EC₅₀ values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity ^[1].

HY-P3506B

Retatrutide acetate LY3437943 acetate	GCGR GLP Receptor	Metabolic Disease
Retatrutide (LY3437943) acetate is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC₅₀ values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide acetate can be used for the research of obesity ^[1].

HY-P3539

Exendin-4 (3-39)	GCGR	Neurological Disease Endocrinology
Exendin-4 (3-39) is a *peptide. Exendin-4 (3-39) is a truncated form of Exendin-4 (HY-13443) that lacks the first two amino acids. Exendin-4 is a potent Glucagon-like peptide-1* receptor (GLP-1r) agonist. Exendin-4 (3-39) and Exendin-4 can be used for the research of diabetic and hypothalamic-pituitary-adrenal (HPA) axis ^[1] .

HY-P3506A

Retatrutide TFA 1 Publications Verification LY3437943 TFA	GLP Receptor GCGR	Metabolic Disease
Retatrutide (LY3437943) TFA is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide TFA binds human GCGR, GIPR, and GLP-1R with EC₅₀ values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide TFA can be used for the research of obesity ^[1].

HY-P0014

Liraglutide 20+ Cited Publications	GCGR GLP Receptor	Metabolic Disease
Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.

HY-108795A

Albiglutide fragment TFA GLP-1-Gly8 TFA; GLP-1 (7-36) analog TFA	GLP Receptor	Metabolic Disease
Albiglutide fragment (GLP-1 (7-36) analog) TFA is an active fragment of Albiglutide (7-36) and a glucagon-like peptide-1 (GLP-1) analog (a long-acting *GLP-1* receptor agonist). Albiglutide is produced by the fusion of DPP-4 resistant GLP-1 dimer with the human albumin gene. Moreover, Albiglutide fragment TFA significantly reduces glycosylated hemoglobin (A1C) and is used in type 2 diabetes (T2D) studies ^[1] .

HY-108795

Albiglutide fragment GLP-1-Gly8; GLP-1 (7-36) analog	GLP Receptor	Metabolic Disease
Albiglutide fragment (GLP-1 (7-36) analog) is an active fragment of Albiglutide (7-36) and a glucagon-like peptide-1 (GLP-1) analog (a long-acting *GLP-1* receptor agonist). Albiglutide is produced by the fusion of DPP-4 resistant GLP-1 dimer with the human albumin gene. Moreover, Albiglutide fragment significantly reduces glycosylated hemoglobin (A1C) and is used in type 2 diabetes (T2D) studies ^[1] .

HY-13443

Exendin-4 Maximum Cited Publications 45 Publications Verification Exenatide	GCGR	Metabolic Disease
Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC₅₀ of 3.22 nM.

HY-13443A

Exendin-4 acetate Maximum Cited Publications 45 Publications Verification Exenatide acetate	GCGR	Metabolic Disease
Exendin-4 acetate (Exenatide acetate), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC₅₀ of 3.22 nM.

HY-P0054

GLP-1(7-36), amide acetate 5+ Cited Publications Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate; Human GLP-1 (7-36), amide acetate	GCGR	Metabolic Disease
GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.

HY-P0054A

GLP-1(7-36), amide Glucagon-like peptide-1 (GLP-1)(7-36), amide; Human GLP-1 (7-36), amide	GCGR	Metabolic Disease
GLP-1(7-36), amide is a physiological incretin hormone that stimulates insulin secretion.

HY-P3491

Pegloxenatide PEX 168	GLP Receptor	Metabolic Disease
Pegloxenatide is a *glucagon-like peptide-1* receptor (GLP-1 RA) agonist. Pegloxenatide can be used for type 2 diabetes** research ^[1].

HY-P0119A

Lixisenatide acetate 2 Publications Verification	GCGR	Metabolic Disease
Lixisenatide acetate is a *glucagon-like peptide-1* (GLP-1) receptor** agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM).

HY-P4407

(D-Asn28)-Exenatide	Peptides	Metabolic Disease
(D-Asn28)-Exenatide is an Exenatide (HY-13443) impurity. Exenatide is a long-acting glucagon-like peptide-1 receptor agonist ^[1].

HY-P4410

(D-Asp28)-Exenatide	Peptides	Metabolic Disease
(D-Asp28)-Exenatide is an Exenatide (HY-13443) impurity. Exenatide is a long-acting glucagon-like peptide-1 receptor agonist ^[1].

HY-103303

CRSP-1	Peptides	Metabolic Disease
CRSP-1 is short for calcitonin receptor-stimulating peptide-1. CRSP-1 inhibits osteoclast formation by inhibiting the formation and activity of multinucleated osteoclast ^[1].

HY-114118

Semaglutide 4 Publications Verification	GCGR	Metabolic Disease
Semaglutide, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 *(GLP-1)* receptor agonist. Semaglutide has the potential for type 2 diabetes treatment.

HY-114118B

Semaglutide acetate 4 Publications Verification	GCGR	Metabolic Disease
Semaglutide acetate, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 *(GLP-1)* receptor agonist. Semaglutide acetate has the potential for type 2 diabetes treatment.

HY-P4858

*C-Peptide 1* (rat)**	GSK-3	Cancer
C-Peptide 1 (rat), a peptide, is aβ-catenin/GSK-3β activator. C-Peptide 1 (rat) can regulate the Wnt/β-catenin signaling pathway. C-Peptide 1 (rat) can be used for the research of cancer ^[1].

HY-114118A

Semaglutide TFA 4 Publications Verification	GCGR	Metabolic Disease
Semaglutide TFA, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 *(GLP-1)* receptor agonist. Semaglutide TFA has the potential for type 2 diabetes treatment.

HY-P10269

GZR18	GLP Receptor	Metabolic Disease
GZR18 is an analog of glucagon-like peptide-1 (GLP-1), which exhibits agonistic activity for GLP-1 receptor, with an EC₅₀ of 0.677 nM. GZR18 ameliorates type 2 diabetes ^[1].

HY-P0054B

GLP-1(7-36), amide TFA 5+ Cited Publications Glucagon-like peptide-1 (GLP-1)(7-36), amide TFA; Human GLP-1 (7-36), amide TFA	GCGR	Metabolic Disease
GLP-1(7-36), amide TFA is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells ^[1].

HY-114118F

Semaglutide, FITC labeled	GCGR	Metabolic Disease
Semaglutide, FITC labeled is a FITC labeled Semaglutide. Semaglutide, a long-acting *GLP-1* alogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide has the potential for type 2 diabetes treatment ^[1].

HY-13443R

Exendin-4 (Standard)	GCGR	Metabolic Disease
Exendin-4 (Standard) is the analytical standard of Exendin-4. This product is intended for research and analytical applications. Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC₅₀ of 3.22 nM.

HY-P0014S2

Liraglutide-13C6,15N TFA	Isotope-Labeled Compounds	Others
Liraglutide- ¹³C₆, ¹⁵N (TFA)is the ¹³C and ¹⁵N labeledLiraglutide(HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus ^[1].

HY-P0014S1

Liraglutide-13C5,15N TFA	Isotope-Labeled Compounds	Others
Liraglutide- ¹³C₅, ¹⁵N (tetraTFA)is the ¹³C and ¹⁵N labeledLiraglutide(HY-P0014) ^[1]. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .

Cat. No.	Product Name	Target	Research Area

HY-P990013

Gulgafafusp alfa	GCGR	Metabolic Disease
Gulgafafusp alfa is a human IgG2κ antibody targeting the glucagon-like peptide 1 receptor *GLP1R* ^[1].

Species:	Human (6) Mouse (2)
Tag:	His (4) SUMO (2) Myc (1) GST (3) Fc (1)
Source:	HEK293 (3) P. pastoris (1) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P70352

	GLP1R Protein, Human (HEK293, Fc) rHuGlucagon-like peptide 1 receptor/GLP1R, Fc; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R	Human	HEK293
	The GLP1R protein is a G protein-coupled receptor for glucagon-like peptide 1 (GLP-1), which upon ligand binding activates adenylyl cyclase and increases cAMP levels. This interaction critically regulates insulin secretion, affecting cellular responses and metabolic processes associated with GLP-1 signaling. GLP1R Protein, Human (HEK293, Fc) is the recombinant human-derived GLP1R protein, expressed by HEK293 , with C-hFc labeled tag. The total length of GLP1R Protein, Human (HEK293, Fc) is 122 a.a., with molecular weight of 50-70 kDa.

HY-P700468

	GLP1R Protein, Human (HEK293, N-His, C-Myc) rHuGlucagon-like peptide 1 receptor/GLP1R, Fc; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R	Human	HEK293
	The GLP1R protein is a G protein-coupled receptor for glucagon-like peptide 1 (GLP-1), which upon ligand binding activates adenylyl cyclase and increases cAMP levels. This interaction critically regulates insulin secretion, affecting cellular responses and metabolic processes associated with GLP-1 signaling. GLP1R Protein, Human (HEK293, N-His, C-Myc) is the recombinant human-derived GLP1R protein, expressed by HEK293 , with C-Myc, N-10*His labeled tag. The total length of GLP1R Protein, Human (HEK293, N-His, C-Myc) is 122 a.a., with molecular weight of 33 kDa.

HY-P70400

	Hepcidin/HAMP Protein, Human (GST) rHuHepcidin/HAMP, GST; Liver-expressed antimicrobial peptide 1; Putative liver tumor regressor; HEPC; LEAP1	Human	E. coli
	The hepcidin/HAMP protein is a liver-produced hormone that is a major circulating regulator of iron absorption and distribution. It promotes endocytosis and degradation of ferroportin/SLC40A1, retaining iron within cells and reducing plasma iron flux. Hepcidin/HAMP Protein, Human (GST) is the recombinant human-derived Hepcidin/HAMP protein, expressed by E. coli , with N-GST labeled tag. The total length of Hepcidin/HAMP Protein, Human (GST) is 25 a.a., with molecular weight of 28-30 kDa.

HY-P700634

	Hepcidin/HAMP Protein, Mouse (GST) 1 Publications Verification rHuHepcidin/HAMP, GST; Liver-expressed antimicrobial peptide 1; Putative liver tumor regressor; HEPC; LEAP1	Mouse	E. coli
	The hepcidin/HAMP protein is a liver-produced hormone that is a major regulator of iron absorption and distribution. It promotes endocytosis and degradation of SLC40A1, retaining iron within cells and reducing plasma iron flux. Hepcidin/HAMP Protein, Mouse (GST) is the recombinant mouse-derived Hepcidin/HAMP protein, expressed by E. coli , with N-GST labeled tag. The total length of Hepcidin/HAMP Protein, Mouse (GST) is 25 a.a., with molecular weight of 29.4 kDa.

HY-P70239

	GLP-1/GCG Protein, Human (HEK293, His) 1 Publications Verification rHuPro-glucagon/GCG, His ; Glucagon; Glicentin; Glicentin-Related Polypeptide; GRPP; Oxyntomodulin; OXM; OXY; Glucagon; Glucagon-Like peptide 1; GLP-1; Incretin Hormone; Glucagon-like peptide 1; GLP-1; Glucagon-Like peptide 2; GLP-2; GCG	Human	HEK293
	GLP-1 and GCG are two proteins derived from the same precursor protein, which is encoded by the GCG-glucagon gene. The GCG protein is a counterregulatory hormone to insulin, playing a crucial role in glucose metabolism by increasing gluconeogenesis and reducing glycolysis to regulate blood glucose levels. GLP-1 protein, secreted by intestinal endocrine cells, promotes insulin secretion, regulates gastrointestinal motility, and inhibits the secretion of GCG protein. GLP-1/GCG protein, Human (HEK293, His), is a recombinant GLP-1/GCG protein expressed by HEK293 cells, with a His tag at the C-terminus, and is composed of 160 amino acids (R21-K180).

HY-P72206

	GLP1R Protein, Mouse (His-SUMO) Glp1r; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R	Mouse	E. coli
	GLP1R protein, a G-protein coupled receptor, binds to GLP-1, activating adenylyl cyclase and increasing intracellular cAMP levels. This interaction regulates insulin secretion and maintains glucose homeostasis. GLP1R can also form dimers with GIPR, suggesting complex regulatory mechanisms and interactions with other receptors. GLP1R Protein, Mouse (His-SUMO) is the recombinant mouse-derived GLP1R protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of GLP1R Protein, Mouse (His-SUMO) is 124 a.a., with molecular weight of ~30.4 kDa.

HY-P700614

	Calcitonin/CALCA Protein, Human (P. pastoris, His-SUMO) CALCA; CALC1Calcitonin gene-related peptide 1; Alpha-type CGRP; Calcitonin gene-related peptide I; CGRP-I	Human	P. pastoris
	Calcitonin/CALCA protein acts as a vasodilator, dilating different blood vessels, including coronary, cerebral, and systemic vessels. Its presence in the central nervous system suggests its potential role as a neurotransmitter or neuromodulator. Calcitonin/CALCA Protein, Human (P. pastoris, His-SUMO) is the recombinant human-derived Calcitonin/CALCA protein, expressed by P. pastoris , with N-SUMO, N-6*His labeled tag. The total length of Calcitonin/CALCA Protein, Human (P. pastoris, His-SUMO) is 37 a.a., with molecular weight of 22 kDa.

HY-P71702

	Calcitonin/CALCA Protein, Human (GST) CALCA; CALC1Calcitonin gene-related peptide 1; Alpha-type CGRP; Calcitonin gene-related peptide I; CGRP-I	Human	E. coli
	Calcitonin/CALCA protein acts as a vasodilator, dilating different blood vessels, including coronary, cerebral, and systemic vessels. Its presence in the central nervous system suggests its potential role as a neurotransmitter or neuromodulator. Calcitonin/CALCA Protein, Human (GST) is the recombinant human-derived Calcitonin/CALCA protein, expressed by E. coli , with N-GST labeled tag. The total length of Calcitonin/CALCA Protein, Human (GST) is 36 a.a., with molecular weight of ~30.6 kDa.

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Species
Source
Tag
Accession
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HY-P81160

	GLP-1R Antibody Glucagon like peptide-1 receptor; GLP 1 R; GLP 1 receptor; GLP 1R; Glp1r; GLP; glp1r; Glucagon like peptide 1 receptor; RATGL1RCP; Glip; MGC138331; GLP-1-R; GLP1R_HUMAN; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R; Precursor.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse, Rat
	GLP-1R Antibody is an unconjugated, approximately 51 kDa, rabbit-derived, anti-GLP-1R polyclonal antibody. GLP-1R Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, ICC, IF expriments in human, mouse, rat, and predicted: dog background without labeling.

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Cat. No.	Product Name		Classification

HY-151696

TCO-PEG3-maleimide		TCO
TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides) .

Cat. No.	Product Name		Classification

HY-130463

POPG sodium salt PG(16:0/18:1); 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol)		Phospholipids
POPG sodium salt is a phospholipid molecule having one negative charge, which can interact with the positive charges of peptides .