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Results for "

platelet receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	PDGFR (19) Platelet-activating Factor Receptor (PAFR) (23) 5-HT Receptor (8) Acyltransferase (1) Adenosine Receptor (4) Adenylate Cyclase (4) Adrenergic Receptor (5) Angiotensin Receptor (1) Antibiotic (1) Apoptosis (22) Autophagy (12) Bacterial (9) Biochemical Assay Reagents (1) c-Fms (1) c-Kit (3) Calcium Channel (5) CDK (1) COX (3) Cyclin G-associated Kinase (GAK) (1) Cytochrome P450 (1) Dengue Virus (1) Dopamine Receptor (1) Drug Isomer (1) Drug Metabolite (7) EGFR (1) Endogenous Metabolite (18) ERK (2) Estrogen Receptor/ERR (3) FGFR (1) Flavivirus (1) FLT3 (1) FXR (2) G Protein-coupled Receptor Kinase (GRK) (1) Glycoprotein VI (4) Histamine Receptor (1) Insulin Receptor (1) Integrin (27) Isotope-Labeled Compounds (14) JAK (4) LDLR (1) Leukotriene Receptor (3) Liposome (1) Lipoxygenase (1) MEK (1) Nucleoside Antimetabolite/Analog (7) Organoid (2) P2X Receptor (2) P2Y Receptor (39) p38 MAPK (2) PARP (1) Phosphodiesterase (PDE) (1) Phospholipase (1) PKC (4) PPAR (2) Prostaglandin Receptor (30) Protease Activated Receptor (PAR) (21) RET (1) Serotonin Transporter (1) SHP2 (2) Src (1) STAT (1) Survivin (1) Syk (3) Thrombin (3) Thrombopoietin Receptor (15) Vasopressin Receptor (4) VEGFR (4)
By Research Areas:	Cancer (58) Cardiovascular Disease (154) Endocrinology (18) Infection (10) Inflammation/Immunology (50) Metabolic Disease (17) Neurological Disease (7)
Oligonucleotides:	Aptamers (3) Phospholipids (2)

250

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

R-96544	5-HT Receptor	Cardiovascular Disease
R-96544 is an orally active 5-HT_2A receptor antagonist. R-96544 can inhibit platelet aggregation in vitro .

TRAP-6 4 Publications Verification PAR-1 agonist peptide; Thrombin receptor Activator Peptide 6	Protease Activated Receptor (PAR)	Inflammation/Immunology
TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective *protease activating receptor* 1 (PAR1)** agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4 .

Atopaxar E5555; ER-172594-00	Protease Activated Receptor (PAR) JAK Apoptosis	Cardiovascular Disease Cancer
Atopaxar (E5555) is a potent, orally active, selective and reversible thrombin receptor *protease-activated receptor-1 (PAR-1)* antagonist. Atopaxar, an antiplatelet agent, interferes with platelet signaling. Atopaxar can be used for the research of atherothrombotic disease .

Parmodulin 2 2 Publications Verification ML161	Protease Activated Receptor (PAR)	Cardiovascular Disease
Parmodulin 2 (ML161) is an allosteric inhibitor of *protease-activated receptor* 1 (PAR1) with an IC₅₀** of 0.26 μM . Parmodulin 2 is a potent and non-competitive inhibitor of SFLLRN-induced P-selectin expression leading to inhibition of platelet aggregation in vitro and platelet thrombus formation in vivo .

Benafentrine maleate AH 21-132	Platelet-activating Factor Receptor (PAFR) Phosphodiesterase (PDE)	Cancer
Benafentrine maleate is a platelet activating factor receptor (PAFR) antagonist and a PDE 4 inhibitor .

Roxifiban	Integrin	Cardiovascular Disease
Roxifiban is a **platelet glycoprotein (GP) IIb/IIIa receptor** inhibitor that can be used in the study of angina .

AH23848 hemicalcium salt	Prostaglandin Receptor	Cardiovascular Disease
AH23848 hemicalcium salt is a potent, specific and orally active thromboxane receptor blocker. AH23848 hemicalcium salt inhibits platelet deposition .

Roxifiban acetate DMP 754	Integrin	Cardiovascular Disease
Roxifiban (acetate) is the acetate form of Roxifiban (HY-10307). Roxifiban (acetate) is a **platelet glycoprotein (GP) IIb/IIIa receptor** inhibitor that can be used in research related to angina .

Atopaxar hydrobromide E5555 hydrobromide; ER 172594-06	Protease Activated Receptor (PAR) JAK Apoptosis	Cardiovascular Disease Cancer
Atopaxar (E5555) hydrobromide is a potent, orally active, selective and reversible thrombin receptor *protease-activated receptor-1 (PAR-1)* antagonist. Atopaxar hydrobromide, an antiplatelet agent, interferes with platelet signaling. Atopaxar hydrobromide can be used for the research of atherothrombotic disease .

R-96544 free base	5-HT Receptor	Inflammation/Immunology
R-96544 (free base) is a potent, selective and competitive 5-HT2 receptor antagonist. R-96544 (free base) inhibits platelet aggregation induced by serotonin, and inhibits 5-HT2A receptor-mediated contraction of guinea pig trachea .

Elarofiban RWJ-53308	Integrin	Cardiovascular Disease
Elarofiban (RWJ-53308) is a nonpeptide, orally active antagonist for *fibrinogen receptor* α_IIbβ₃ (GPIIb/IIIa), with an IC₅₀** of 0.15 nM. Elarofiban has the potential for platelet mediated thrombotic disorders research .

Lamifiban Ro 44-9883	Integrin	Cardiovascular Disease
Lamifiban is a nonpeptide glycoprotein IIb/IIIa receptor and platelet aggregation antagonist. Lamifiban in combination with thrombolytic therapy effectively restores coronary arterial patency. Lamifiban is promising for research of acute coronary syndromes .

Lamifiban TFA	Integrin	Cardiovascular Disease
Lamifiban TFA is a nonpeptide glycoprotein IIb/IIIa receptor and platelet aggregation antagonist. Lamifiban TFA in combination with thrombolytic therapy effectively restores coronary arterial patency. Lamifiban TFA is promising for research of acute coronary syndromes .

Elarofiban diTFA	Integrin	Cardiovascular Disease
Elarofiban diTFA is the salt form of Elarofiban (HY-10315) with two TFA. Elarofiban diTFA is a nonpeptide, orally active antagonist for *fibrinogen receptor* α_IIbβ₃ (GPIIb/IIIa), with an IC₅₀** of 0.15 nM. Elarofiban diTFA has the potential for platelet mediated thrombotic disorders research .

Eptifibatide acetate 5+ Cited Publications	Integrin	Cardiovascular Disease
Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

Eptifibatide 5+ Cited Publications	Integrin	Cardiovascular Disease
Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

Eptifibatide monoacetate	Integrin	Cardiovascular Disease
Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

L662,025	Platelet-activating Factor Receptor (PAFR)	Metabolic Disease Inflammation/Immunology
L662,025 is a specific, photolabile and irreversible **Platelet-activating factor (PAF-receptor) antagonist, with IC₅₀** values of 5.6 μM (platelet aggregation) and 1 μM (receptor binding), respectively .

(±)-Clopidogrel hydrochloride	P2Y Receptor	Cardiovascular Disease
(±)-Clopidogrel hydrochloride is an antithrombotic agent that is ADP-selective and orally available. (±)-Clopidogrel hydrochloride inhibits platelet aggregation by inhibiting the binding of ADP to its platelet receptors .

EP 171	Thrombin	Cardiovascular Disease
EP 171 is a TP receptor agonist and human platelet activator. EP 171 can induce constriction of guinea pig trachea, and the constriction can be inhibited by the TP receptor antagonist EP 092. EP 171 binds to TP receptors on intact human platelets with an IC₅₀ of 2.9 nM .

PSB-0739 1 Publications Verification	P2Y Receptor	Cardiovascular Disease
PSB-0739 is a high-affinity potent, competitive, nonselective platelet P2Y₁₂ receptor antagonist with a K_i values of 24.9 nM. The P2Y₁₂ receptor plays a crucial role in platelet aggregation. Antithrombotic effect .

E-6123	Platelet-activating Factor Receptor (PAFR)	Inflammation/Immunology
E-6123 is a platelet-activating factor (PAF) receptor antagonist.

PAF-AN-1	Platelet-activating Factor Receptor (PAFR)	Cardiovascular Disease Inflammation/Immunology
PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist.

Hexanolamino PAF C-16 1-O-Hexa-decyl-2-acetyl-sn-glycero-3-phospho(N,N,N-trimethyl)-hexanolamine	Platelet-activating Factor Receptor (PAFR)	Cardiovascular Disease
Hexanolamino PAF C-16 (1-O-hexadecyl-2-acetyl-sn-glycero-3-phospho (N,N,N trimethyl) hexanolamine) is a Platelet-activating Factor Receptor (PAFR) Modulator with partial agonist activity. Hexanolamino PAF C-16 induces platelet aggregation and macrophage production but fails to increase [Ca2+]i in platelets, suggesting that PAF receptors may interact with PAF receptors through Ca ²⁺-dependent and -independent pathways. Related to platelet aggregation .

Fibrinogen-Binding Peptide 1 Publications Verification	Thrombin	Cardiovascular Disease
Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin .

CP-96486	Leukotriene Receptor	Inflammation/Immunology
CP-96486 is a potent and orally active leukotriene D₄ (LTD₄)/platelet activating factor (PAF) receptor antagonist with K_is of 20 and 24 nM, respectively.

BN 52111	Platelet-activating Factor Receptor (PAFR)	Cardiovascular Disease
BN 52111 is a potent platelet-activating factor (PAF) receptor antagonist .

Fibrinogen-Binding Peptide TFA 1 Publications Verification	Integrin	Cardiovascular Disease
Fibrinogen-Binding Peptide TFA (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide TFA binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin .

L 651142	Platelet-activating Factor Receptor (PAFR)	Cardiovascular Disease
L 651142 is a weak **platelet activating factor (PAF) receptor** antagonist. L 651142 inhibits the binding of [ ³H]PAF to rabbit platelet, human platelet or human lung membranes with K_is of 0.839 μM, 1.82 μM, 3.64 μM, respectively .

Prasugrel PCR 4099	P2Y Receptor	Cardiovascular Disease
Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .

KUM 32	Adrenergic Receptor Adenylate Cyclase	Cardiovascular Disease
KUM 32 is a potent antagonist of epinephrine-induced platelet aggregation. KUM 32 is an adenylate cyclase activity inhibitor. KUM 32 binds to the alpha 2 adrenergic receptor of human platelets .

Prasugrel hydrochloride PCR 4099 hydrochloride	P2Y Receptor	Cardiovascular Disease
Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .

R-138727	P2Y Receptor	Cardiovascular Disease
R-138727, the thiol-containing active metabolite of Prasugrel, is an irreversible platelet P2Y12 receptor inhibitor. R-138727 inhibits ADP-induced platelet aggregation .

Eptifibatide (acetate) (Standard)	Integrin	Cardiovascular Disease
Eptifibatide (acetate) (Standard) is the analytical standard of Eptifibatide (acetate). This product is intended for research and analytical applications. Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

16(S)-Iloprost	Prostaglandin Receptor	Cardiovascular Disease
16(S)-Iloprost is a stereoisomer of Iloprost. 16(S)-Iloprost inhibited platelet aggregation with IC₅₀ value of 3.5 nM, and balanced binding with platelet membrane receptors K_d value of 13.4 nM .

Prasugrel (Maleic acid) PCR 4099 (Maleic acid)	P2Y Receptor	Cardiovascular Disease
Prasugrel (PCR 4099) Maleic acid is a thienopyridine and proagent, inhibits platelet function. Prasugrel Maleic acid is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .

CP-96021 hydrochloride	Leukotriene Receptor	Inflammation/Immunology
CP-96021 hydrochloride is a balanced, combined, potent and orally active *leukotriene D4 (LTD4)/platelet* activating factor (PAF)** receptor antagonist with K_i values of 34 nM and 37 nM, respectively .

Troleandomycin (Standard)	Antibiotic Cytochrome P450 Bacterial	Infection Inflammation/Immunology
Eptifibatide (acetate) (Standard) is the analytical standard of Eptifibatide (acetate). This product is intended for research and analytical applications. Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

Ticlopidine hydrochloride 1 Publications Verification	Adenosine Receptor	Cardiovascular Disease
Ticlopidine hydrochloride is an adenosine diphosphate (ADP) receptor inhibitor against platelet aggregation with IC50 of ~2 μM.

Variabilin Homopisatin	Integrin	Cardiovascular Disease
Variabilin (Homopisatin) is a potent RGD-containing antagonist of glycoprotein IIb-IIIa and platelet aggregation inhibitor from the hard tick Dermacentor variabilis. Variabilin potently inhibits platelet aggregation induced by the platelet agonists ADP, collagen, and thrombin receptor peptide SFLLRNP. Variabilin also blocks platelet adhesion to immobilized Fg. In addition, Variabilin inhibits binding of purified human GPIIb-IIIa to immobilized Fg .

Epiyangambin	Platelet-activating Factor Receptor (PAFR)	Inflammation/Immunology Cancer
Epiyangambin is a competitive platelet activating factor receptor (PAF) antagonist that dose-dependently inhibits PAF-induced platelet aggregation. Epiyangambin also inhibits the growth of human colon cancer cells (SW480 cells) .

(S)-S007-1558 1 Publications Verification GPVI antagonist 1	Glycoprotein VI	Cardiovascular Disease
(S)-S007-1558 (compound 5) is a glycoprotein VI (GPVI) platelet receptor antagonist. (S)-S007-1558 inhibits collagen-induced platelet aggregation with an IC₅₀ of 25.3 μM .

SQ 26655	Prostaglandin Receptor	Cardiovascular Disease
SQ 26655 is a TxA₂ receptor agonist. SQ 26655 induces human platelet aggregation .

Gantofiban	Integrin	Cardiovascular Disease
Gantofiban is a GPIIb/IIIa integrin receptor antagonist. By binding to this receptor, Gantofiban can effectively inhibit platelet aggregation, thereby exerting its antithrombotic effect .

Ticagrelor 5+ Cited Publications AZD6140; AR-C 126532XX	P2Y Receptor	Cardiovascular Disease Cancer
Ticagrelor (AZD6140) is a reversible oral P2Y12 receptor antagonist for the treatment of platelet aggregation.

UR-2922	Integrin	Others
UR-2922 is a platelet GPIIb/IIIa antagonist with antiplatelet aggregation and cardiovascular disease inhibition activities. UR-2922 has high affinity for human platelet receptors and has good pharmacokinetic properties, and can be used to inhibit cardiovascular diseases.

Cat. No.	Product Name	Type

HY-W127502

1-Hexadecylglycero-3-phosphate 1-Hex-GPA	Cell Assay Reagents
1-Hexadecyl lysophosphatidic acid is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group in the sn-1 position. LPA binds to five different G protein-coupled receptors and mediates a variety of biological responses, including cell proliferation, smooth muscle contraction, platelet aggregation, neurite contraction, and cell motility.

Cat. No.	Product Name	Target	Research Area

HY-P0078

TRAP-6 4 Publications Verification PAR-1 agonist peptide; Thrombin receptor Activator Peptide 6	Protease Activated Receptor (PAR)	Inflammation/Immunology
TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective *protease activating receptor* 1 (PAR1)** agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4 .

HY-B0686B

Eptifibatide acetate Maximum Cited Publications 7 Publications Verification	Integrin	Cardiovascular Disease
Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

HY-B0686

Eptifibatide Maximum Cited Publications 7 Publications Verification	Integrin	Cardiovascular Disease
Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

HY-P1741

Fibrinogen-Binding Peptide 1 Publications Verification	Thrombin	Cardiovascular Disease
Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin .

HY-P1741A

Fibrinogen-Binding Peptide TFA 1 Publications Verification	Integrin	Cardiovascular Disease
Fibrinogen-Binding Peptide TFA (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide TFA binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin .

HY-P3531

Fibrinogen γ-chain (397-411)	Peptides	Others
Fibrinogen γ-chain (397-411), a esidues 397-411 of the γ chain of fibrinogen, is a site recognizing the platelet receptor, which is distinct from the site(s) involved in polymerization of fibrin monomers .

HY-B0686A

Eptifibatide monoacetate	Integrin	Cardiovascular Disease
Eptifibatide monoacetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

HY-B0686BR

Eptifibatide (acetate) (Standard)	Integrin	Cardiovascular Disease
Eptifibatide (acetate) (Standard) is the analytical standard of Eptifibatide (acetate). This product is intended for research and analytical applications. Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity .

HY-P1711

L 366763	Peptides	Cardiovascular Disease
L 366763 is a potent peptide that acts as a fibrinogen receptor antagonist, preventing collagen-induced platelet aggregation and adhesion. L 366763 inhibits platelet deposition and maintains blood flow in a baboon thrombosis model, significantly prolonging bleeding time. L 366763 has antithrombotic efficacy, whereas recombinant LAPP does not have the same effect .

HY-P3082

SKF 106760	Peptides	Cardiovascular Disease
SKF 106760 is a potent platelet fibrin receptor (glycoprotein IIb/IIIa) antagonist with significant antiplatelet and antithrombotic activities. SKF 106760 inhibits platelet aggregation in dogs in vitro and prevents thrombus formation in stenotic carotid arteries. SKF 106760 has also shown elimination effects against aspirin-resistant thrombi that develop in the setting of high-grade stenosis .

HY-P10918

F11R peptide TFA	Peptides	Inflammation/Immunology
F11R peptide TFA is a F11 receptor molecule. F11R peptide TFA inhibits anti-F11R antibody-induced platelet aggregation, and inhibits the adhesion of platelets to cytokine (TNFα and INF-γ)-inflammed endothelial cells. F11R peptide TFA can be used for research of atherosclerotic plaques and associated thrombotic disease .

HY-P4004

PAR-4 (1-6) amide (human)	Protease Activated Receptor (PAR)	Inflammation/Immunology
PAR-4 (1-6) amide human is an N-terminal fragment of protease-activated receptor 4 (PAR4). PAR-4 (1-6) amide human induce platelet aggregation .

HY-P1313A

PAR 4 (1-6) (TFA) GYPGQV TFA	Protease Activated Receptor (PAR)	Others
PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide, is a fragment of protease-activated receptor 4 (PAR₄). PAR 4 (1-6) TFA acts as a PAR₄-specific agonist .

HY-P10577

RAG8 peptide	Protease Activated Receptor (PAR)	Cardiovascular Disease
RAG8 peptide is an antagonist for *protease-activated receptor* 4 (PAR 4*), which inhibits late-stage platelet* activation, and reduces thrombosis without altering hemostasis or increasing bleeding risk. RAG8 peptide can be used for atherosclerosis research .

HY-P10119

PDGFR Y1021 peptide (non-phosphorylation)	PDGFR	Others
PDGFR Y1021 peptide (non-phosphorylation) is the non-phosphorylated fragment of platelet-derived growth factor receptor (PDGFR). PDGFR Y1021 peptide (non-phosphorylation) blocks the PLCγ association to PDGFR through PLCγSH2 domain, and thus inhibits mitogenic response .

HY-P10270

PDGFR Y1021 peptide (phosphorylation)	PDGFR	Others
PDGFR Y1021 peptide (phosphorylation) is the phosphorylated fragment of platelet-derived growth factor receptor (PDGFR). PDGFR Y1021 peptide (phosphorylation) supports association of PLCγ to PDGFR through PLCγSH2 domains, and thus promotes the production of inositol phosphates and mitogenic response .

HY-P3444

CD31 PECAM-1	SHP2 Bacterial	Metabolic Disease Inflammation/Immunology
CD31 (PECAM-1) is platelet endothelial cell adhesion molecule-1, serves as the endothelial cell-specific receptor of clostridium perfringens b-Toxin (CPB). CD31 is also an ER-MP12 antigen, acts as a linker between mechanical stress, metabolism and inflammation. CD31 peptide is able to sustain phosphorylation of the CD31 ITIM₆₈₆ and of SHP2 and to inhibit TCR-induced T-cell activation ^- .

HY-P5875

P4pal10	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
P4pal10 is an antagonist for *protease-activated receptor* 4 (PAR4)*. P4pal10 inhibits the platelet* aggregation, inhibits tissue factor (TF)-induced thrombin generation, and exhibits anticoagulant and antithrombotic activities. P4pal10 reduces the oedema and the granulocyte infiltration induced by Carrageenan (HY-125474). P4pal10 ameliorates the injury in mice myocardial ischemia/reperfusion (I/R) models .

HY-P3444A

CD31 TFA PECAM-1 TFA	SHP2 Bacterial	Metabolic Disease Inflammation/Immunology
CD31 (PECAM-1) TFA is platelet endothelial cell adhesion molecule-1, serves as the endothelial cell-specific receptor of clostridium perfringens b-Toxin (CPB). CD31 TFA is also an ER-MP12 antigen, acts as a linker between mechanical stress, metabolism and inflammation. CD31 TFA peptide is able to sustain phosphorylation of the CD31 ITIM₆₈₆ and of SHP2 and to inhibit TCR-induced T-cell activation ^- .

HY-P5875A

P4pal10 TFA	Protease Activated Receptor (PAR)	Cardiovascular Disease Inflammation/Immunology
P4pal10 TFA is the TFA salt form of P4pal10 (HY-P5875). P4pal10 TFA is an antagonist for *protease-activated receptor* 4 (PAR4)*. P4pal10 TFA inhibits the platelet* aggregation, inhibits tissue factor (TF)-induced thrombin generation, and exhibits anticoagulant and antithrombotic activities. P4pal10 TFA reduces the oedema and the granulocyte infiltration induced by Carrageenan (HY-125474). P4pal10 TFA ameliorates the injury in rats myocardial ischemia/reperfusion (I/R) models .

Cat. No.	Product Name	Target	Research Area

HY-P990685

Romiplostim	Thrombopoietin Receptor	Inflammation/Immunology
Romiplostim is a fusion protein analogue of TPO (thrombopoietin protein) Fc peptide, and is a peptide-body molecule. Romiplostim increases platelet production by activating the thrombopoietin receptor TPO receptor. The peptidosome molecule has two identical single-stranded subunits, each consisting of 269 amino acid residues .

HY-P9922

Olaratumab IMC-3G3; LY3012207	PDGFR	Cancer
Olaratumab (IMC-3G3; LY3012207) is an anti-platelet-derived growth factor receptor alpha (PDGFRα) human monoclonal IgG1 antibody with antitumor activity .

HY-P9934

Abciximab 1 Publications Verification C7E3	Integrin	Cardiovascular Disease
Abciximab (C7E3), a chimeric mouse/human monoclonal antibody fragment, is a glycoprotein (GP) IIb/IIIa inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors .

Species:	Human (13) Rhesus Macaque (4) Mouse (4) Rat (6) Cynomolgus (3)
Tag:	His (18) Avi (3) Fc (12)
Source:	HEK293 (28) Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P70180

	GPVI Protein, Mouse (HEK293, His) 1 Publications Verification rMuGlycoprotein 6 (platelet)/GPVI, His ; Glycoprotein 6; glycoprotein VI (platelet); GP6; GPIV; GPVI; GPVIplatelet collagen receptor; MGC138168; platelet glycoprotein VI	Mouse	HEK293
	GPVI Protein is a platelet membrane protein with a molecular weight of ~62 kDa that is a physiological collagen receptor. GPVI is present as a complex with the homodimeric Fc receptor y-chain. GPVI must form such a dimeric complex to exhibit high affinity binding to collagen. The GPVI-induced activation mechanism is initiated by tyrosine phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of the FcR gamma-chain, and then this signal is transduced to many related proteins, mainly by tyrosine phosphorylation. Interaction of platelets with collagen via the receptor GPVI results in platelet activation and adhesion. GPVI Protein, Mouse (HEK293, His) is the recombinant mouse-derived GPVI protein, expressed by HEK293 , with C-6*His labeled tag. The total length of GPVI Protein, Mouse (HEK293, His) is 244 a.a., with molecular weight of 40-60 kDa.

HY-P73721

	PDGF R alpha Protein, Rat (HEK293, His) platelet-derived growth factor receptor alpha; PDGFR-alpha; PDGFR-2; CD140a; PDGFRA	Rat	HEK293
	PDGF R alpha protein is a tyrosine protein kinase receptor for PDGFA, PDGFB, and PDGFC that coordinates embryonic development, cell proliferation, survival, and chemotaxis. Their functions vary, promoting or inhibiting cell proliferation and migration depending on the situation. PDGF R alpha Protein, Rat (HEK293, His) is the recombinant rat-derived PDGF R alpha protein, expressed by HEK293 , with C-His labeled tag.

HY-P72494

	PDGF R beta Protein, Human (HEK293, His) platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB	Human	HEK293
	TRF1 protein is a telomere-binding protein that plays a crucial role in telomere maintenance and chromosome stability. It is involved in regulating telomere length and preventing DNA damage. PDGF R beta Protein, Human (HEK293, His) is the recombinant human-derived PDGF R beta protein, expressed by HEK293 , with C-6*His labeled tag. The total length of PDGF R beta Protein, Human (HEK293, His) is 499 a.a., with molecular weight of 85-130 kDa.

HY-P72495

	PDGF R alpha Protein, Human (HEK293, His) platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-2; CD140a; PDGFRA	Human	HEK293
	PDGF R α is a tyrosine protein kinase and an important cell surface receptor for PDGFA, PDGFB and PDGFC, affecting embryonic development, cell proliferation, survival and chemotaxis. Its effects on cell behavior vary, promoting or inhibiting proliferation and migration depending on environmental cues. PDGF R alpha Protein, Human (HEK293, His) is the recombinant human-derived PDGF R alpha protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72496

	PDGF R alpha Protein, Mouse (HEK293, His) platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-2; CD140a; PDGFRA	Mouse	HEK293
	PDGF R α is a tyrosine-protein kinase receptor with critical effects on embryonic development, cell proliferation, survival, and chemotaxis.Its effects on cell behavior vary depending on the environment and is critical for differentiation of bone marrow mesenchymal stem cells, normal skeletal development, embryonic skull closure, and gastrointestinal mucosal formation.PDGF R alpha Protein, Mouse (HEK293, His) is the recombinant mouse-derived PDGF R alpha protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P702756

	PDGF R beta Protein, Human (Biotinylated, sf9, His, Avi) PDGFRB; platelet-derived growth factor receptor, beta polypeptide; PDGFR; platelet-derived growth factor receptor beta; CD140b; JTK12; PDGFR1; PDGFR-beta; PDGF-R-beta; CD140 antigen-like family member B; platelet-derived growth factor receptor 1; beta-type platelet-derived growth factor receptor; CD140B; PDGFR-1	Human	Sf9 insect cells
	PDGF Rβ protein is integral in embryonic development and regulates cell proliferation, survival, differentiation, chemotaxis, migration, and vascular development. It crucially recruits pericytes and smooth muscle cells to the endothelium, promoting vascular smooth muscle cell migration and neointimal formation at the site of injury. PDGF R beta Protein, Human (Biotinylated, sf9, His, Avi) is the recombinant human-derived PDGF R beta, expressed by Sf9 insect cells , with Avi, His labeled tag. ,

HY-P75969

	PEAR1 Protein, Rat (sf9, His) platelet endothelial aggregation receptor 1; Multiple EGF-like domains protein 12; PEAR1; MEGF12	Rat	Sf9 insect cells
	The PEAR1 protein is characterized by the absence of conserved residues critical for feature annotation propagation, prompting exploration of its structural and functional implications. This unique feature indicates potential changes in molecular interactions and biological activity. PEAR1 Protein, Rat (sf9, His) is the recombinant rat-derived PEAR1 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of PEAR1 Protein, Rat (sf9, His) is 752 a.a., with molecular weight of ~78.9 kDa.

HY-P73356

	PDGF R alpha Protein, Human (HEK293, Fc) platelet-derived growth factor receptor alpha; PDGFR-alpha; PDGFR-2; CD140a; PDGFRA	Human	HEK293
	PDGF R α is a tyrosine protein kinase and an important cell surface receptor for PDGFA, PDGFB and PDGFC, affecting embryonic development, cell proliferation, survival and chemotaxis. Its effects on cell behavior vary, promoting or inhibiting proliferation and migration depending on environmental cues. PDGF R alpha Protein, Human (HEK293, Fc) is the recombinant human-derived PDGF R alpha protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P73722

	PDGF R alpha Protein, Rat (HEK293, Fc) platelet-derived growth factor receptor alpha; PDGFR-alpha; PDGFR-2; CD140a; PDGFRA	Rat	HEK293
	PDGF R alpha protein is a tyrosine protein kinase receptor for PDGFA, PDGFB, and PDGFC that coordinates embryonic development, cell proliferation, survival, and chemotaxis. Their functions vary, promoting or inhibiting cell proliferation and migration depending on the situation. PDGF R alpha Protein, Rat (HEK293, Fc) is the recombinant rat-derived PDGF R alpha protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P74645

	PDGF R alpha Protein, Mouse (HEK293, Fc) platelet-derived growth factor receptor alpha; PDGFR-alpha; PDGFR-2; CD140a; PDGFRA	Mouse	HEK293
	PDGF R α is a tyrosine-protein kinase receptor with critical effects on embryonic development, cell proliferation, survival, and chemotaxis. Its effects on cell behavior vary depending on the environment and is critical for differentiation of bone marrow mesenchymal stem cells, normal skeletal development, embryonic skull closure, and gastrointestinal mucosal formation. PDGF R alpha Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived PDGF R alpha protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P73360

	PDGF R beta Protein, Rat (HEK293, His) platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB	Rat	HEK293
	PDGF R beta Protein, a receptor tyrosine kinase, binds ligands PDGFA, PDGFB, and PDGFD, forming homodimers or heterodimers.Ligand binding activates diverse signaling cascades in PDGF R beta, with responses contingent on the specific ligand.The modulation of responses involves heterodimer formation with another receptor, PDGFRB.PDGF R beta Protein, Rat (HEK293, His) is the recombinant rat-derived PDGF R beta protein, expressed by HEK293 , with C-His labeled tag.

HY-P74644

	PDGF R beta Protein, Rat (HEK293, Fc) platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB	Rat	HEK293
	PDGF R beta Protein, a receptor tyrosine kinase, binds ligands PDGFA, PDGFB, and PDGFD, forming homodimers or heterodimers.Ligand binding activates diverse signaling cascades in PDGF R beta, with responses contingent on the specific ligand.The modulation of responses involves heterodimer formation with another receptor, PDGFRB.PDGF R beta Protein, Rat (HEK293, Fc) is the recombinant rat-derived PDGF R beta protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77124

	PDGF R beta Protein, Human (HEK293, Fc) platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB	Human	HEK293
	TRF1 protein is a telomere-binding protein that plays a crucial role in telomere maintenance and chromosome stability. It is involved in regulating telomere length and preventing DNA damage. PDGF R beta Protein, Human (HEK293, Fc) is the recombinant human-derived PDGF R beta protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PDGF R beta Protein, Human (HEK293, Fc) is 498 a.a., with molecular weight of ~82.8 KDa.

HY-P703816

	PDGF R beta Protein, Cynomolgus (HEK293, His) platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB	Cynomolgus	HEK293

HY-P77127

	PDGF R beta Protein, Human (Biotinylated, HEK293, His) platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB	Human	HEK293
	TRF1 protein is a telomere-binding protein that plays a crucial role in telomere maintenance and chromosome stability. It is involved in regulating telomere length and preventing DNA damage. PDGF R beta Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived PDGF R beta protein, expressed by HEK293 , with C-His labeled tag. The total length of PDGF R beta Protein, Human (Biotinylated, HEK293, His) is 499 a.a., with molecular weight of ~57.6 KDa.

HY-P77128

	PDGF R beta Protein, Rhesus Macaque (HEK293, Fc) platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB	Rhesus Macaque	HEK293
	PDGF R beta, a tyrosine-protein kinase receptor, crucially regulates embryonic development, overseeing cell processes like proliferation, survival, differentiation, chemotaxis, and migration. Especially vital in blood vessel development, it facilitates pericyte and smooth muscle cell proliferation, migration, and recruitment to endothelial cells, playing a significant role in blood vessel formation and maintenance. PDGF R beta Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived PDGF R beta protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77129

	PDGF R beta Protein, Rhesus Macaque (HEK293, His) platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB	Rhesus Macaque	HEK293
	PDGF R beta, a tyrosine-protein kinase receptor, crucially regulates embryonic development, overseeing cell processes like proliferation, survival, differentiation, chemotaxis, and migration. Especially vital in blood vessel development, it facilitates pericyte and smooth muscle cell proliferation, migration, and recruitment to endothelial cells, playing a significant role in blood vessel formation and maintenance. PDGF R beta Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived PDGF R beta protein, expressed by HEK293 , with C-His labeled tag. The total length of PDGF R beta Protein, Rhesus Macaque (HEK293, His) is 498 a.a., with molecular weight of ~80-96 KDa.

HY-P77123

	PDGF R beta Protein, Human (HEK293, C-His-Avi) platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB	Human	HEK293
	PDGF Rβ protein is integral in embryonic development and regulates cell proliferation, survival, differentiation, chemotaxis, migration, and vascular development. It crucially recruits pericytes and smooth muscle cells to the endothelium, promoting vascular smooth muscle cell migration and neointimal formation at the site of injury. PDGF R beta Protein, Human (HEK293, C-His-Avi) is the recombinant human-derived PDGF R beta protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

HY-P70948

	JAM-A/CD321 Protein, Human (HEK293, His) Junctional Adhesion Molecule A; JAM-A; Junctional Adhesion Molecule 1; JAM-1; platelet F11 receptor; platelet Adhesion Molecule 1; PAM-1; CD321; F11R; JAM1; JCAM	Human	HEK293
	The JAM-A/CD321 protein is critical for the formation of epithelial tight junctions, is present in early junction development, and recruits PARD3. Binding of the PARD6-PARD3 complex may hinder PARD3-JAM1 interaction, thereby impeding tight junction assembly. JAM-A/CD321 Protein, Human (HEK293, His) is the recombinant human-derived JAM-A/CD321 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70004

	CD36 Protein, Human (HEK293, Fc ) rHuplatelet glycoprotein 4/CD36, Fc; Fatty acid translocase; Glycoprotein IIIb; FATCHDS7; Leukocyte differentiation antigen CD36; PAS IV; platelet collagen receptor; SCARB3; Thrombospondin receptor; CD36	Human	HEK293
	CD36 is a multifunctional glycoprotein that serves as a receptor for a variety of ligands, including thrombospondin and oxidized low-density lipoprotein. Ligand induces CD36 clusters, initiating signal transduction and internalization. CD36 Protein, Human (HEK293, Fc ) is the recombinant human-derived CD36 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD36 Protein, Human (HEK293, Fc ) is 410 a.a., with molecular weight of 90-130 kDa.

HY-P70962

	VISTA/B7-H5 Protein, Cynomolgus (HEK293, His) platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Cynomolgus	HEK293
	VISTA/B7-H5 Protein is a B7 family member that maintains T cell and myeloid quiescence and is a promising target for combination cancer immunotherapy. VISTA not only acts as a ligand expressed on antigenpresenting cells, but also functions as a receptor on T cells. VISTA inhibits T cell activation, proliferation, and cytokine production. VISTA/B7-H5 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of VISTA/B7-H5 Protein, Cynomolgus (HEK293, His) is 162 a.a., with molecular weight of 30-50 kDa.

HY-P73482

	VISTA/B7-H5 Protein, Cynomolgus (HEK293, Fc) platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Cynomolgus	HEK293
	VISTA/B7-H5 Protein is a B7 family member that maintains T cell and myeloid quiescence and is a promising target for combination cancer immunotherapy. VISTA not only acts as a ligand expressed on antigenpresenting cells, but also functions as a receptor on T cells. VISTA inhibits T cell activation, proliferation, and cytokine production. VISTA/B7-H5 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of VISTA/B7-H5 Protein, Cynomolgus (HEK293, Fc) is 162 a.a., with molecular weight of ~44.9 kDa.

HY-P73546

	VISTA/B7-H5 Protein, Rat (HEK293, Fc) platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Rat	HEK293
	VISTA/B7-H5 protein, an immunoregulatory receptor, inhibits T-cell response and may regulate embryonic stem cell differentiation by inhibiting BMP4 signaling. It also stimulates MMP14-mediated MMP2 activation, suggesting a role in matrix metalloproteinase processes. These roles highlight the significance of VISTA/B7-H5 in immune regulation, embryonic development, and extracellular matrix dynamics. VISTA/B7-H5 Protein, Rat (HEK293, Fc) is the recombinant rat-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of VISTA/B7-H5 Protein, Rat (HEK293, Fc) is 159 a.a., with molecular weight of ~44.7 kDa.

HY-P73547

	VISTA/B7-H5 Protein, Mouse (HEK293, Fc) platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Mouse	HEK293
	VISTA/B7-H5 Protein is a type I transmembrane protein expressed primarily in white blood cells that inhibits T cell function. VISTA/B7-H5 Protein promotes embryonic stem cell differentiation by inhibiting BMP4 signaling and stimulates MMP14 mediated MMP2 activation. VISTA/B7-H5 Protein is highly expressed in tumors. VISTA/B7-H5 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P73544

	VISTA/B7-H5 Protein, Rhesus Macaque (HEK293, His) platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Rhesus Macaque	HEK293
	VISTA/B7-H5 protein is an immune regulatory receptor that can inhibit the activation of T cells and regulate immune responses as a ligand and receptor. VISTA/B7-H5 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-His labeled tag. The total length of VISTA/B7-H5 Protein, Rhesus Macaque (HEK293, His) is 162 a.a., with molecular weight of ~19.6 kDa.

HY-P73545

	VISTA/B7-H5 Protein, Rhesus Macaque (HEK293, Fc) platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Rhesus Macaque	HEK293
	VISTA/B7-H5 protein is an immune regulatory receptor that can inhibit the activation of T cells and regulate immune responses as a ligand and receptor. VISTA/B7-H5 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of VISTA/B7-H5 Protein, Rhesus Macaque (HEK293, Fc) is 194 a.a., with molecular weight of ~44.9 kDa.

HY-P78936

	VISTA/B7-H5 Protein, Human (Biotinylated, HEK293, His-Avi) platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Human	HEK293
	VISTA/B7-H5 protein, an immunoregulatory receptor, inhibits T-cell response and may regulate embryonic stem cell differentiation by inhibiting BMP4 signaling. It also stimulates MMP14-mediated MMP2 activation, suggesting a role in matrix metalloproteinase processes. These roles highlight the significance of VISTA/B7-H5 in immune regulation, embryonic development, and extracellular matrix dynamics. VISTA/B7-H5 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of VISTA/B7-H5 Protein, Human (Biotinylated, HEK293, His-Avi) is 162 a.a., with molecular weight of 36-47 kDa.

HY-P75784

	G6B Protein, Human (HEK293, Fc) Megakaryocyte and platelet inhibitory receptor G6b; Protein G6b; MPIG6B; C6orf25; G6B-B	Human	HEK293
	The G6B protein is an inhibitory receptor critical for hematopoietic lineage differentiation, megakaryocyte function, and platelet production. Its effects include inhibiting platelet aggregation and activation induced by agonists such as ADP and collagen-related peptides. G6B Protein, Human (HEK293, Fc) is the recombinant human-derived G6B protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P75785

	G6B Protein, Human (HEK293, His) Megakaryocyte and platelet inhibitory receptor G6b; Protein G6b; MPIG6B; C6orf25; G6B-B	Human	HEK293
	The G6B protein is an inhibitory receptor critical for hematopoietic lineage differentiation, megakaryocyte function, and platelet production. Its effects include inhibiting platelet aggregation and activation induced by agonists such as ADP and collagen-related peptides. G6B Protein, Human (HEK293, His) is the recombinant human-derived G6B protein, expressed by HEK293 , with C-His labeled tag.

HY-P70983

	VISTA/B7-H5 Protein, Human (HEK293, His) VISTA; B7-H5; platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Human	HEK293
	VISTA/B7-H5 protein, an immunoregulatory receptor, inhibits T-cell response and may regulate embryonic stem cell differentiation by inhibiting BMP4 signaling. It also stimulates MMP14-mediated MMP2 activation, suggesting a role in matrix metalloproteinase processes. These roles highlight the significance of VISTA/B7-H5 in immune regulation, embryonic development, and extracellular matrix dynamics. VISTA/B7-H5 Protein, Human (HEK293, His) is the recombinant human-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-15284S1

Prasugrel-d3
Prasugrel-d₃ is the deuterium labeled Prasugrel. Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[1].

HY-15284S

Prasugrel-d5
Prasugrel-d₅ is deuterium labeled Prasugrel. Prasugrel (PCR 4099), a thienopyridine and prodrug, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[1].

HY-15284S2

Prasugrel-d4
Prasugrel-d₄ is the deuterium labeled Prasugrel[1]. Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation[2].

HY-15284S3

Prasugrel-13C6
Prasugrel-13C6 is a deuterated labeled Prasugrel . Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .

HY-B0153AS

Ticlopidine-d4 hydrochloride
Ticlopidine-d₄ (hydrochloride) is the deuterium labeled Ticlopidine hydrochloride. Ticlopidine hydrochloride is an adenosine diphosphate (ADP) receptor inhibitor against platelet aggregation with IC50 of ~2 μM.

HY-10064S

Ticagrelor-d7
Ticagrelor-d₇ is the deuterium labeled Ticagrelor. Ticagrelor (AZD6140) is a reversible oral P2Y12 receptor antagonist for the treatment of platelet aggregation[1][2].

HY-10064S1

Ticagrelor-d4
Ticagrelor-d₄ (AZD6140-d₄) is deuterium labeled Ticagrelor. Ticagrelor (AZD6140) is a reversible oral P2Y12 receptor antagonist for the treatment of platelet aggregation.

HY-17000S

Tolvaptan-d7
Tolvaptan-d₇ is the deuterium labeled Tolvaptan. Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation[1][2].

HY-10119S

Vorapaxar-d5
Vorapaxar-d₅ is deuterated labeled Vorapaxar (HY-10119). Vorapaxar (SCH 530348), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor *protease-activated receptor* (PAR-1) antagonist (K_i*=8.1 nM). Vorapaxar (SCH 530348) inhibits thrombin receptor-activating peptide (TRAP)-induced platelet* aggregation in a dose-dependent manner .

HY-13463BS

Avatrombopag-d8 hydrochloride

Avatrombopag-d₈ (hydrochloride) is deuterium labeled Avatrombopag (hydrochloride). Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A[1][2][3].

HY-B2158S

Chlorotrianisene-d9
Chlorotrianisene-d₉ is the deuterium labeled Chlorotrianisene. Chlorotrianisene is a long-acting non-steroidal estrogen and an orally active estrogen receptor modulator. Chlorotrianisene exhibits antiestrogenic activity. Chlorotrianisene potently inhibits the enzyme COX-1 and inhibits platelet aggregation in whole blood[1][2][3].

HY-B0228S

Adenosine-d1
Adenosine-d is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[1][2].

HY-W779021

Adenosine-15N
Adenosine- ¹⁵N (Adenine riboside- ¹⁵N) is ¹⁵N labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .

HY-B0228S1

Adenosine-13C5
Adenosine- ¹³C₅ is the ¹³C labeled Adenosine[1]. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[2][3].

HY-15306S

Eltrombopag-13C4

1 Publications Verification

Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .}

HY-130304S

8-Isoprostaglandin E2-d4

8-Isoprostaglandin E2-d₄ (iPE2-III-d₄) is deuterium labeled 8-Isoprostaglandin E2. 8-Isoprostaglandin E2 (iPE2-III) is a member of the isoprostane class of prostanoids. 8-Isoprostaglandin E2 acts at the receptor for thromboxane A₂ (the TP) in vivo to induce vasoconstriction and platelet aggregation. 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway .

HY-B0131S

Prostaglandin E1-d4

Prostaglandin E1-d₄ is the deuterium labeled Prostaglandin E1. Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases[1][2][3].

HY-B0228S13

Adenosine-13C10

Adenosine- ¹³C₁₀ (Adenine riboside- ¹³C₁₀; D-Adenosine- ¹³C₁₀) is ¹³C-labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

HY-B0228S12

Adenosine-d13

Adenosine-d₁₃ (Adenine riboside-d₁₃; D-Adenosine-d₁₃) is deuterium labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.

HY-B0228S11

Adenosine-15N5

Adenosine- ¹⁵N₅ (Adenine riboside- ¹⁵N₅; D-Adenosine- ¹⁵N₅) is the ¹⁵N labled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .

HY-W713365

Eltrombopag-d3

Eltrombopag-d₃ (SB-497115-d₃) is deuterium labeled Eltrombopag. Eltrombopag (SB-497115) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag can be used for the research of cardiovascular. Eltrombopag also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag can induce apoptosis in hepatocellular carcinomab (HCC) as well .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82180

	PDGFR beta Antibody (YA1925) PDGFRB; PDGFR; PDGFR1; PDGFRβ; platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; platelet-deri	WB, IP	Human, Mouse, Rat
	PDGFR beta Antibody (YA1925) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1925), targeting PDGFR beta, with a predicted molecular weight of 124 kDa (observed band size: 190 kDa). PDGFR beta Antibody (YA1925) can be used for WB, IP experiment in human, mouse, rat background.

HY-P83317

	Phospho-PDGFR beta (Tyr740) Antibody (YA3062) PDGFRB; PDGFR; PDGFR1; platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; platelet-deri	WB, ICC/IF	Mouse, Rat
	Phospho-PDGFR beta (Tyr740) Antibody (YA3062) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3062), targeting Phospho-PDGFR beta (Tyr740), with a predicted molecular weight of 124 kDa (observed band size: 190 kDa). Phospho-PDGFR beta (Tyr740) Antibody (YA3062) can be used for WB, ICC/IF experiment in mouse, rat background.

HY-P81793

	CD36 Antibody (YA1538) CD36; GP3B; GP4; platelet glycoprotein 4; Fatty acid translocase; FAT; Glycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; platelet collagen receptor; platelet glycoprotein IV; GPIV; Thrombospondin receptor; CD36	WB, IHC-P, IP	Human, Mouse, Rat
	CD36 Antibody (YA1538) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1538), targeting CD36, with a predicted molecular weight of 53 kDa (observed band size: 70-100 kDa). CD36 Antibody (YA1538) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

HY-P83362

	Integrin alpha 2 Antibody (YA3107) ITGA2; CD49B; Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD49b	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	Integrin alpha 2 Antibody (YA3107) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3107), targeting Integrin alpha 2, with a predicted molecular weight of 129 kDa (observed band size: 150 kDa). Integrin alpha 2 Antibody (YA3107) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P83737

	PDGF Receptor beta Antibody (YA3467) PDGFRB; PDGFR; PDGFR1; PDGFRβ; platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-beta; Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; platelet-deri	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	PDGF Receptor beta Antibody (YA3467) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3467), targeting PDGFR beta, with a predicted molecular weight of 124 kDa (observed band size: 190 kDa). PDGFR beta Antibody (YA3467) can be used for WB, IHC-P, IP, FC, IF-Tissue, IF-Cell, mIHC experiment in human, mouse, rat background.

HY-P83280

	Junctional Adhesion Molecule 1 Antibody (YA3025) F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; platelet F11 receptor; platelet adhesion molecule 1; PAM-1; CD321	WB, ICC/IF, IP	Human
	Junctional Adhesion Molecule 1 Antibody (YA3025) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3025), targeting Junctional Adhesion Molecule 1, with a predicted molecular weight of 33 kDa (observed band size: 33 kDa). Junctional Adhesion Molecule 1 Antibody (YA3025) can be used for WB, ICC/IF, IP experiment in human background.

HY-P81531

	VISTA Antibody (YA1276) VSIR; PP2135, UNQ730/PRO1412; C10orf54, SISP1; VISTA; V-type immunoglobulin domain-containing suppressor of T-cell activation; platelet receptor Gi24; Stress-induced secreted protein-1; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor	IHC-P	Human
	VISTA Antibody (YA1276) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1276), targeting VISTA. VISTA Antibody (YA1276) can be used for IHC-P experiment in human background.

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Cat. No.	Product Name		Classification

HY-147079A

Egaptivon pegol sodium ARC 1779 sodium		Aptamers
Egaptivon pegol sodium is an aptamer, which blocks binding of the von Willebrand Factor (VWF) to platelet GPIb receptors. Egaptivon pegol sodium has anti-thrombotic efficacy.

HY-130345

PAF (C18)		Phospholipids
C18-PAF, octadecane PAF, is the ligand of platelet-activating factor and PAF G protein-coupled receptor (PAFR). C18-PAF has renovasodilator properties and antihypertensive lipid properties. C18-PAF increases renal blood flow and causes dose-dependent systemic hypotension .

HY-147079

Egaptivon pegol ARC 1779		Aptamers
Egaptivon pegol (ARC1779) is an aptamer, which blocks binding of the von Willebrand Factor (VWF) to platelet GPIb receptors. Egaptivon pegol has anti-thrombotic efficacy.

HY-W783254

C18 LPA PA(18:0e/0:0)		Phospholipids
C18 LPA (PA(18:0e/0:0)) is a water-soluble phospholipid that functions as a signaling molecule, influencing various cellular responses through G protein-coupled receptors (GPCRs). It is known to promote smooth muscle contraction, cytoskeletal rearrangement, and chemotaxis, while also playing a role in neurotransmitter release, cell proliferation, platelet aggregation, and Ca2+ mobilization. Elevated levels of C18 LPA in human plasma are associated with ovarian cancer and atherosclerosis, suggesting its potential as a biomarker for ovarian cancer.

HY-160053

Gint4.T aptamer sodium		Aptamers
Gint4.T aptamer sodium is a nuclease-resistant RNA aptamer-based antagonist targeting platelet-derived growth factor receptor beta (PDGFRβ) (Kd: 9.6 nM). Gint4.T aptamer sodium inhibits PDGFRβ heterodimerization and EGFR transactivation. It can significantly inhibit cell migration and proliferation, induce differentiation and prevent tumor growth in vivo. Gint4.T aptamer sodium specifically inhibits PDGFRβ-mediated tropism of mesenchymal stem cells (MSCs) toward the tumor microenvironment .

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